Receptor
PDB id Resolution Class Description Source Keywords
4R9W 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF PLATELET FACTOR 4 COMPLEXED WITH FONDAP HOMO SAPIENS PF4 FONDAPARINUX CXC CHEMOKINE PLATELET FACTOR GLYCOSAMIPLATELET CYTOKINE
Ref.: ATOMIC DESCRIPTION OF THE IMMUNE COMPLEX INVOLVED I HEPARIN-INDUCED THROMBOCYTOPENIA. NAT COMMUN V. 6 8277 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ZDO IDS SUS BDP SGN C:1;
Valid;
none;
submit data
1498.18 n/a S(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4R9W 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF PLATELET FACTOR 4 COMPLEXED WITH FONDAP HOMO SAPIENS PF4 FONDAPARINUX CXC CHEMOKINE PLATELET FACTOR GLYCOSAMIPLATELET CYTOKINE
Ref.: ATOMIC DESCRIPTION OF THE IMMUNE COMPLEX INVOLVED I HEPARIN-INDUCED THROMBOCYTOPENIA. NAT COMMUN V. 6 8277 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 4R9W - ZDO IDS SUS BDP SGN n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 4R9W - ZDO IDS SUS BDP SGN n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 4R9W - ZDO IDS SUS BDP SGN n/a n/a
2 1F9P - ESA ESA ESA n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ZDO IDS SUS BDP SGN; Similar ligands found: 16
No: Ligand ECFP6 Tc MDL keys Tc
1 ZDO IDS SUS BDP SGN 1 1
2 IDS SGN IDS SGN IDS SUS IDS SGN 0.761062 0.969231
3 IDY SGN 0.641509 0.984615
4 SGN IDS SGN IDS 0.584746 0.953846
5 IDY SUS 0.558559 0.953846
6 SGN IDS SGN IDS SGN 0.543307 0.954545
7 IDS SGN IDS SGN IDS SGN 0.539062 0.954545
8 SGN IDS SGN IDS SGN UAP 0.534884 0.925373
9 SGN IDS SGN UAP 0.534884 0.925373
10 IDS SGN IDS SGN IDS 0.51938 0.939394
11 BDP NPO GNS IDS GNS BDP GNS 0.514706 0.828947
12 IDS SGN IDS SGN UAP 0.5 0.925373
13 IDY GNX 0.46087 0.939394
14 BDP NPO GNS BDP GNS BDP GNS 0.411765 0.828947
15 GNS IDR GNS IDR GNS IDR GNS IDR 0.409449 0.939394
16 BDP GNS BDP GNS BDP GNS BDP 0.401575 0.939394
Similar Ligands (3D)
Ligand no: 1; Ligand: ZDO IDS SUS BDP SGN; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4R9W; Ligand: ZDO IDS SUS BDP SGN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4r9w.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback