-->
Receptor
PDB id Resolution Class Description Source Keywords
4QM7 1.8 Å EC: 2.7.1.78 STRUCTURE OF BACTERIAL POLYNUCLEOTIDE KINASE BOUND TO GTP AN RUMINICLOSTRIDIUM THERMOCELLUM RNA REPAIR P-LOOP PHOSPHOTRANSFERASE POLYNUCLEOTIDE KINASEHYDROLASE-DNA COMPLEX TRANSFERASE-DNA COMPLEX
Ref.: STRUCTURES OF BACTERIAL POLYNUCLEOTIDE KINASE IN A COMPLEX WITH NUCLEOSIDE TRIPHOSPHATE (NTP)-MG2+ AND RNA AND A MIXED SUBSTRATE-PRODUCT COMPLEX WITH NTP-A 5'-PHOSPHORYLATED OLIGONUCLEOTIDE. J.BACTERIOL. V. 196 4285 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GTP A:1001;
B:1001;
Valid;
Valid;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG A:1002;
B:1002;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
DC DC DT DG C:1;
Valid;
none;
submit data
974.509 n/a P(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4QM7 1.8 Å EC: 2.7.1.78 STRUCTURE OF BACTERIAL POLYNUCLEOTIDE KINASE BOUND TO GTP AN RUMINICLOSTRIDIUM THERMOCELLUM RNA REPAIR P-LOOP PHOSPHOTRANSFERASE POLYNUCLEOTIDE KINASEHYDROLASE-DNA COMPLEX TRANSFERASE-DNA COMPLEX
Ref.: STRUCTURES OF BACTERIAL POLYNUCLEOTIDE KINASE IN A COMPLEX WITH NUCLEOSIDE TRIPHOSPHATE (NTP)-MG2+ AND RNA AND A MIXED SUBSTRATE-PRODUCT COMPLEX WITH NTP-A 5'-PHOSPHORYLATED OLIGONUCLEOTIDE. J.BACTERIOL. V. 196 4285 2014
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4JT2 - CTP C9 H16 N3 O14 P3 C1=CN(C(=O....
2 4JT4 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
3 4JST - UTP C9 H15 N2 O15 P3 C1=CN(C(=O....
4 4QM7 - DC DC DT DG n/a n/a
5 4JSY - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4JT2 - CTP C9 H16 N3 O14 P3 C1=CN(C(=O....
2 4JT4 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
3 4JST - UTP C9 H15 N2 O15 P3 C1=CN(C(=O....
4 4QM7 - DC DC DT DG n/a n/a
5 4JSY - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4JT2 - CTP C9 H16 N3 O14 P3 C1=CN(C(=O....
2 4JT4 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
3 4JST - UTP C9 H15 N2 O15 P3 C1=CN(C(=O....
4 4QM7 - DC DC DT DG n/a n/a
5 4JSY - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 156
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 9GM 0.809524 0.973684
9 GNP 0.809524 0.973684
10 GCP 0.797619 0.973684
11 5GP 0.797468 0.986486
12 G 0.797468 0.986486
13 GMV 0.764706 0.973684
14 G2R 0.764045 0.961039
15 G5P 0.755319 0.973684
16 GTG 0.752688 0.936709
17 G2P 0.747126 0.961039
18 G3A 0.744681 0.973684
19 GDD 0.741935 0.961039
20 GDC 0.741935 0.961039
21 GKE 0.741935 0.961039
22 0O2 0.736264 0.986486
23 GP2 0.729412 0.961039
24 6CK 0.726316 0.936709
25 Y9Z 0.723404 0.902439
26 GPG 0.717391 0.961039
27 GFB 0.715789 0.961039
28 GDR 0.715789 0.961039
29 GPD 0.704082 0.925
30 GKD 0.693878 0.961039
31 JB2 0.693878 0.961039
32 GDX 0.686869 0.973684
33 ALF 5GP 0.685393 0.888889
34 GH3 0.681319 0.973333
35 YGP 0.677083 0.901235
36 G3D 0.67033 0.986486
37 GDP AF3 0.659574 0.888889
38 ALF GDP 0.659574 0.888889
39 GDP ALF 0.659574 0.888889
40 DGT 0.659341 0.923077
41 GMP 0.658228 0.88
42 G4P 0.655914 0.986486
43 JB3 0.653846 0.948718
44 NGD 0.647619 0.961039
45 CAG 0.642202 0.880952
46 2MD 0.62963 0.891566
47 MGP 0.619565 0.961039
48 U2G 0.616822 0.936709
49 6G0 0.612903 0.961039
50 MGD 0.612613 0.891566
51 TPG 0.608696 0.840909
52 CG2 0.605505 0.936709
53 GDP 7MG 0.601942 0.911392
54 FEG 0.601852 0.879518
55 G G 0.598039 0.948052
56 ZGP 0.59633 0.869048
57 PGD 0.591304 0.925
58 MD1 0.591304 0.891566
59 3GP 0.590909 0.946667
60 GPX 0.581633 0.946667
61 DGI 0.580645 0.923077
62 IDP 0.576087 0.972973
63 DBG 0.567797 0.948718
64 2GP 0.555556 0.96
65 FE9 0.555556 0.776596
66 G4M 0.547619 0.880952
67 BGO 0.544643 0.924051
68 GCP G 0.543689 0.921053
69 ATP 0.537634 0.92
70 HEJ 0.537634 0.92
71 G1G 0.533898 0.925
72 AQP 0.531915 0.92
73 5FA 0.531915 0.92
74 A G 0.525862 0.935065
75 G A A A 0.525862 0.923077
76 U A G G 0.521368 0.935065
77 HFD 0.520833 0.873418
78 R5I 0.520408 0.946667
79 R7I 0.520408 0.946667
80 01G 0.518868 0.902439
81 P2G 0.510638 0.883117
82 ITT 0.510638 0.868421
83 AKW 0.504348 0.890244
84 GGM 0.504274 0.901235
85 G1R G1R 0.504065 0.924051
86 DGP 0.5 0.910256
87 PGD O 0.5 0.850575
88 MGO 0.5 0.864198
89 DG 0.5 0.910256
90 P1G 0.5 0.871795
91 GTA 0.495495 0.936709
92 PRT 0.490741 0.959459
93 B4P 0.489362 0.894737
94 AP5 0.489362 0.894737
95 IMP 0.489362 0.959459
96 G U 0.487179 0.9
97 7DT 0.484536 0.906667
98 GPC 0.479339 0.879518
99 G C 0.478992 0.9
100 BA3 0.478723 0.894737
101 ADP 0.473684 0.92
102 G2Q 0.471698 0.961039
103 6YZ 0.470588 0.896104
104 G7M 0.46875 0.948052
105 C1Z 0.462963 0.986486
106 25L 0.458716 0.907895
107 A2D 0.457447 0.894737
108 RGT 0.45045 0.909091
109 AGS 0.45 0.873418
110 SAP 0.45 0.873418
111 SGP 0.44898 0.82716
112 A4P 0.445378 0.869048
113 G G G RPC 0.442623 0.875
114 ANP 0.441176 0.896104
115 ACQ 0.441176 0.896104
116 8GT 0.441176 0.875
117 APC G U 0.44 0.886076
118 AT4 0.438776 0.884615
119 G U34 0.438017 0.888889
120 6AD 0.436893 0.841463
121 G G G C 0.433071 0.9125
122 UP5 0.432203 0.873418
123 PCG 0.431373 0.933333
124 C2E 0.431373 0.921053
125 35G 0.431373 0.933333
126 A G C C 0.429688 0.911392
127 T99 0.427184 0.884615
128 5GP 5GP 0.427184 0.883117
129 TAT 0.427184 0.884615
130 AR6 0.425743 0.894737
131 APR 0.425743 0.894737
132 7DD 0.424242 0.906667
133 AN2 0.424242 0.907895
134 DG DG 0.423423 0.865854
135 AD9 0.421569 0.896104
136 M33 0.42 0.883117
137 7D4 0.42 0.835443
138 UCG 0.419847 0.911392
139 HDV 0.419048 0.825
140 H6Y 0.419048 0.946667
141 G C C C 0.416667 0.924051
142 ACP 0.415842 0.896104
143 T5A 0.414634 0.802326
144 A1R 0.412844 0.839506
145 ADQ 0.412844 0.871795
146 MGQ 0.412844 0.935897
147 A3R 0.412844 0.839506
148 MGT 0.411215 0.823529
149 A G U 0.410072 0.888889
150 93A 0.41 0.833333
151 A22 0.407407 0.907895
152 CA0 0.405941 0.896104
153 ATF 0.40566 0.884615
154 AGO 0.404762 0.888889
155 MGV 0.401786 0.890244
156 CGP 0.4 0.86747
Ligand no: 2; Ligand: DC DC DT DG ; Similar ligands found: 23
No: Ligand ECFP6 Tc MDL keys Tc
1 DC DC DT DG 1 1
2 DT DT DT 0.653061 0.891892
3 DT DC 0.642202 0.958904
4 DT DT PST 0.609524 0.846154
5 DT ME6 DT 0.582609 0.92
6 DT DA DC DG 0.58042 0.833333
7 DC DG DT DA 0.576389 0.833333
8 DT DT DT DT DT 0.560748 0.868421
9 THP 0.505155 0.864865
10 DT MA7 DT 0.496296 0.841463
11 DA DT DA DA 0.477612 0.839506
12 DC DG 0.460938 0.797619
13 DU DU DU DU BRU DU DU 0.45082 0.820513
14 PAX 0.448529 0.829268
15 T3P 0.443299 0.864865
16 ATY 0.435185 0.820513
17 DC DG DA DC 0.431507 0.785714
18 DG DC 0.430657 0.785714
19 DG DA DC DG 0.426667 0.788235
20 DU DU DU DU BRU DG DU 0.425532 0.790698
21 DA DC DG DA 0.422078 0.776471
22 NYM 0.421569 0.855263
23 3PD UM3 0.412214 0.817073
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4QM7; Ligand: GTP; Similar sites found with APoc: 913
This union binding pocket(no: 1) in the query (biounit: 4qm7.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 3LRE ADP None
2 4YDS ATP None
3 1VG1 GDP None
4 1DAK ADP None
5 1DAK DPU None
6 4DKX GDP None
7 2BEK ATP None
8 4XGU ADP None
9 1IN4 ADP None
10 2IL4 COA None
11 4U5X GNP None
12 2Q4V ACO None
13 4I4B NAD None
14 2WPX ACO None
15 6G96 ACO None
16 3REF GDP None
17 3K9U ACO None
18 5FII PHE None
19 1OBV FMN None
20 1U3G THF None
21 2O66 FLC None
22 2WPW ACO None
23 1C3Q TZE None
24 2VOH CIT None
25 2X77 GDP 1.16959
26 3FKQ ATP 1.16959
27 4YJ1 ADP 1.16959
28 4D9M 0JO 1.16959
29 6BMM OLB 1.16959
30 3LN9 FLC 1.43885
31 5O3Q CMP 1.66667
32 1Y63 ADP 1.75439
33 2WKQ GTP 1.75439
34 5TIV A3P 1.75439
35 2VOS ADP 1.75439
36 5BYK OAQ 1.75439
37 5BYK A3P 1.75439
38 3QVV 3QV 1.75439
39 3QVV A3P 1.75439
40 4BAS GNP 1.75439
41 3MGB PAP 1.75439
42 3AB4 THR 1.75439
43 1GY8 NAD 1.75439
44 1TIQ COA 1.75439
45 4KOT CE3 1.85185
46 4KVX ACO 1.92308
47 5DXV NAP 1.92308
48 2OZE AGS 2.33918
49 3SBD GNP 2.33918
50 5WC2 ADP 2.33918
51 3RC3 ANP 2.33918
52 5BQ5 ADP BEF 2.33918
53 3IO3 ADP 2.33918
54 4FCW ADP 2.33918
55 4LJ9 ACP 2.33918
56 1NST A3P 2.33918
57 3SXN COA 2.33918
58 5T2U NAP 2.33918
59 1YBH FAD 2.33918
60 3H4L ANP 2.33918
61 1MH1 GNP 2.33918
62 4M3P HCS 2.33918
63 5A96 GTP 2.33918
64 2PD4 NAD 2.33918
65 2PD4 DCN 2.33918
66 1BO4 COA 2.38095
67 1SQ5 ADP 2.92398
68 2YOH WMJ 2.92398
69 4TTQ ATP 2.92398
70 3ZQ6 ADP ALF 2.92398
71 5FG3 GDP 2.92398
72 4J0Q GDP 2.92398
73 3WY9 GDP 2.92398
74 5Z69 AGS 2.92398
75 5KSP GDP 2.92398
76 3WYA GDP 2.92398
77 5W7Q GDP 2.92398
78 1HSK FAD 2.92398
79 5MEX PAP 2.92398
80 1M7B GTP 2.92398
81 2TPL HPP 2.92398
82 1GWN GTP 2.92398
83 3AYI HCI 2.92398
84 1EBG PAH 2.92398
85 2W2X GSP 2.92398
86 4NE2 ADP 2.92398
87 3AYI FAD 2.92398
88 5MEX SZZ 2.92398
89 3MB5 SAM 2.92398
90 2AL2 2PG 2.92398
91 2AL2 PEP 2.92398
92 4NE2 SH2 2.92398
93 3TE4 ACO 2.92398
94 4X7G 3Y8 2.92398
95 1ESM COA 2.92398
96 1Z2A GDP 2.97619
97 1CJW COT 3.01205
98 4RZ3 ADP 3.05085
99 5G1N PAL 3.18471
100 4PPF FLC 3.50877
101 1GOJ ADP 3.50877
102 1BG2 ADP 3.50877
103 1M7G AV2 3.50877
104 2WHX ADP 3.50877
105 5UIV ADP 3.50877
106 2QQ0 TMP 3.50877
107 2QQ0 ADP 3.50877
108 2QQ0 ANP 3.50877
109 2QQ0 THM 3.50877
110 1YZQ GNP 3.50877
111 3QXC ATP 3.50877
112 2WOJ ADP ALF 3.50877
113 3ZS9 ADP ALF 3.50877
114 1I4D GDP 3.50877
115 4E03 ADP 3.50877
116 4PX9 ADP 3.50877
117 3DKP ADP 3.50877
118 4GOX A3P 3.50877
119 4PJ3 ANP 3.50877
120 1RYH GNP 3.50877
121 3KC1 2T6 3.50877
122 2CHG ANP 3.50877
123 1P3D ANP 3.50877
124 1M7G ADP 3.50877
125 2ZW5 COA 3.50877
126 1GQY ACP 3.50877
127 1M7G ADX 3.50877
128 5NM7 GLY 3.50877
129 2JJK R15 3.50877
130 1YY5 FAD 3.50877
131 4ZCC NAI 3.50877
132 1RSG FAD 3.50877
133 1DL5 SAH 3.50877
134 2PTZ PAH 3.50877
135 6H5E ANP 3.50877
136 5J5R 6G1 3.50877
137 5J5R IMP 3.50877
138 1VG8 GNP 3.50877
139 3W8X FTK 3.50877
140 3W8X FAD 3.50877
141 1PVN MZP 3.50877
142 1VKO NAD 3.50877
143 3HVJ 705 3.50877
144 4R3L COA 3.50877
145 1WUU ANP 3.50877
146 3B8I OXL 3.50877
147 6CB2 OLC 3.50877
148 3C3Y SAH 3.50877
149 4FUT ATP 3.50877
150 4KAX GTP 3.5503
151 4WOP CTP 3.55556
152 5FAG PPI 3.65854
153 3N5C GDP 3.7037
154 1KSH GDP 3.94737
155 3COB ADP 4.09357
156 6A20 ADP 4.09357
157 1F9V ADP 4.09357
158 2GDJ ANP 4.09357
159 2NCD ADP 4.09357
160 2JLR ANP 4.09357
161 1V8K ANP 4.09357
162 2Y8E GNP 4.09357
163 2FFQ GSP 4.09357
164 4LC1 GDP 4.09357
165 1DAR GDP 4.09357
166 1NHX PEP 4.09357
167 1NHX FTB 4.09357
168 5ZBR ANP 4.09357
169 2GMV PEP 4.09357
170 3B7G ANP 4.09357
171 3T34 GDP 4.09357
172 3FYH ADP 4.09357
173 1G3Q ADP 4.09357
174 4UTG ANP 4.09357
175 4R43 GDP 4.09357
176 2GMV UN8 4.09357
177 1H74 ADP 4.09357
178 5H7K GDP 4.09357
179 5WRJ A3P 4.09357
180 4B5P ACO 4.09357
181 2GK6 ADP 4.09357
182 5WRI A3P 4.09357
183 4GBM A3P 4.09357
184 4H6U ACO 4.09357
185 3PCR GTP 4.09357
186 2C9O ADP 4.09357
187 1ION ADP 4.09357
188 2A5F GTP 4.09357
189 2MBR EPU 4.09357
190 2MBR FAD 4.09357
191 1OJ4 ANP 4.09357
192 2FH5 GTP 4.09357
193 4AVB ACO 4.09357
194 1U7Z PMT 4.09357
195 4JLS 3ZE 4.09357
196 5H4S RAM 4.09357
197 1NV8 SAM 4.09357
198 1NV8 MEQ 4.09357
199 3BY9 SIN 4.09357
200 4ZDJ UTP 4.09357
201 4N9I PCG 4.09357
202 5KF9 ACO 4.09357
203 2ZX2 RAM 4.09357
204 4ZBA GDS 4.09357
205 1H65 GDP 4.09357
206 4DV8 0LX 4.09357
207 1H74 ILE 4.09357
208 5J7X FAD 4.09357
209 1N2X SAM 4.09357
210 1RM6 FAD 4.09357
211 5GM1 SAH 4.09357
212 1XTT U5P 4.09357
213 4N02 FNR 4.09357
214 1WWZ ACO 4.40252
215 1HE1 GDP 4.44444
216 5K5Z ANP 4.4586
217 3TMK T5A 4.62963
218 4Q1A 2XZ 4.67836
219 4Q1A UDP 4.67836
220 2XT3 ADP 4.67836
221 1T5C ADP 4.67836
222 5GVR LMR 4.67836
223 4ZKD GDP 4.67836
224 2RCN GDP 4.67836
225 1F5N GNP 4.67836
226 2ZE7 AMP 4.67836
227 1WF3 GNP 4.67836
228 1KMQ GNP 4.67836
229 2HCJ GDP 4.67836
230 1VG9 GDP 4.67836
231 4XOI GTP 4.67836
232 1KK1 GNP 4.67836
233 1TX4 ALF GDP 4.67836
234 1VG0 GDP 4.67836
235 1S7N COA 4.67836
236 5BVE 4VG 4.67836
237 4ZCW 4NG 4.67836
238 3EZ2 ADP 4.67836
239 1NY5 ADP 4.67836
240 5HPY GDP 4.67836
241 1GHE ACO 4.67836
242 4WEI GLC GAL 4.67836
243 5K04 COA 4.67836
244 5JCP GDP ALF 4.67836
245 4JB1 NAP 4.67836
246 4JB1 FAD 4.67836
247 2J5V PCA 4.67836
248 4XSH GSP 4.67836
249 5IRC GDP 4.67836
250 2VZZ SCA 4.67836
251 2GWH A3P 4.67836
252 2VVM PRO 4.67836
253 2VVM FAD 4.67836
254 1OTH PAO 4.67836
255 1BZY IMU 4.67836
256 1ZRH A3P 4.67836
257 2ZE7 DST 4.67836
258 4TMZ GSP 4.67836
259 2HS3 FGR 4.67836
260 4NCN GTP 4.67836
261 5J1J ANP 4.67836
262 3M31 FAD 4.67836
263 1ZBQ NAD 4.67836
264 1G3M A3P 4.7619
265 1G3M PCQ 4.7619
266 5Z2M GTP 5.07246
267 4ZNL BEF ADP 5.10949
268 2VVG ADP 5.26316
269 5U32 GDP 5.26316
270 3DC4 ADP 5.26316
271 3W5J GDP 5.26316
272 3HU3 AGS 5.26316
273 3P4X ADP 5.26316
274 2ZR9 DTP 5.26316
275 5W75 SUC 5.26316
276 3ZFD ANP 5.26316
277 5LB3 ADP 5.26316
278 1UJ2 C5P 5.26316
279 4LYA ATP 5.26316
280 4UXH T5A 5.26316
281 1UJ2 ADP 5.26316
282 5MZN ADP 5.26316
283 5W75 GDP 5.26316
284 2J0V GDP 5.26316
285 2WJG GDP 5.26316
286 5IFS ADP 5.26316
287 3QF7 ANP 5.26316
288 4D81 ADP 5.26316
289 3V2U ATP 5.26316
290 4V03 ADP 5.26316
291 5TVJ 7LF 5.26316
292 3BER AMP 5.26316
293 5TVJ COA 5.26316
294 1QSM ACO 5.26316
295 3R7F CP 5.26316
296 2FNA ADP 5.26316
297 5AE2 FYC 5.26316
298 2Z3Y F2N 5.26316
299 1VKJ A3P 5.26316
300 1JQ3 AAT 5.26316
301 5AE2 FAD 5.26316
302 1M2O GNP 5.26316
303 4XTR ADP 5.26316
304 3Q9L ATP 5.26316
305 4XTR ATP 5.26316
306 4XVU ATP 5.26316
307 1PK8 ATP 5.26316
308 5LU5 M7P 5.26316
309 1QAN SAH 5.26316
310 1OW3 GDP 5.3719
311 2QTV GNP 5.38922
312 2WJH GDP 5.42169
313 2WJH FLC 5.42169
314 2VBQ BSJ 5.45455
315 1B0U ATP 5.72519
316 5ZXD ATP 5.84795
317 4P4T GDP 5.84795
318 4TMK T5A 5.84795
319 1XP8 AGS 5.84795
320 5LEF GTP 5.84795
321 2QZ4 ADP 5.84795
322 2DPY ADP 5.84795
323 4IHQ ADP 5.84795
324 5O74 GDP 5.84795
325 1KY3 GDP 5.84795
326 6G14 G4P 5.84795
327 4KBF AMP 5.84795
328 2YG3 FAD 5.84795
329 1ZD9 GDP 5.84795
330 2VTD LKM 5.84795
331 2ZPA ADP 5.84795
332 1G7C 5GP 5.84795
333 2FAH GDP 5.84795
334 4RFM 3P6 5.84795
335 1QF5 RPL 5.84795
336 1QF5 GDP 5.84795
337 4RD0 GDP 5.84795
338 3OJF NDP 5.84795
339 3OJF IMJ 5.84795
340 4JK3 NAD 5.84795
341 3NKV GNP 5.84795
342 5THY SAH 5.84795
343 1OYY AGS 5.84795
344 2B8T THM 5.84795
345 5SZH GNP 5.84795
346 2ZPA ACO 5.84795
347 1KAO GDP 5.98802
348 3BFX A3P 6.41892
349 1G6H ADP 6.43275
350 2KIN ADP 6.43275
351 1X6V ADP 6.43275
352 1TQ4 GDP 6.43275
353 2Y65 ADP 6.43275
354 1OIV GDP 6.43275
355 1SVM ATP 6.43275
356 5TSH ADP 6.43275
357 1JJV ATP 6.43275
358 5JCZ GDP 6.43275
359 2JAQ DCP 6.43275
360 5TSH ANP 6.43275
361 1ZC3 GNP 6.43275
362 5M04 GDP 6.43275
363 4QOS ADP 6.43275
364 6BSX E7S 6.43275
365 2CJW GDP 6.43275
366 2ORV 4TA 6.43275
367 4LPS GDP 6.43275
368 4P3Y GDP 6.43275
369 3U6B GDP 6.43275
370 2PL3 ADP 6.43275
371 5XDR ADP 6.43275
372 2B8W ALF 5GP 6.43275
373 1D8T GDP 6.43275
374 5JBQ GDP 6.43275
375 1F6B GDP 6.43275
376 4G5G GDP 6.43275
377 4IOK XPO 6.43275
378 4IOK ADP 6.43275
379 1VHT BA3 6.43275
380 3U6K GDP 6.43275
381 1R6B ADP 6.43275
382 2OBM ADP 6.43275
383 4DCT GDP 6.43275
384 4HI0 GDP 6.43275
385 1B7T ADP 6.43275
386 3A1S GDP 6.43275
387 3DZD ADP 6.43275
388 4PC3 GDP 6.43275
389 4PFO ADP 6.43275
390 1JBW ACQ 6.43275
391 2A9K GDP 6.43275
392 2BCG GDP 6.43275
393 1FP6 ADP 6.43275
394 2BVN GNP 6.43275
395 1X8J A3P 6.43275
396 1JBW TMF 6.43275
397 5EE5 GTP 6.43275
398 3ZJ0 ACO 6.43275
399 5J1S ATP 6.43275
400 4DDY DN6 6.43275
401 3FWY ADP 6.43275
402 3IUY AMP 6.43275
403 2PEZ GGZ 6.43275
404 2PEZ DAT 6.43275
405 4M9Q GNP 6.43275
406 1DUV PSQ 6.43275
407 3QKT ANP 6.43275
408 1Q19 APC 6.43275
409 2F9L GDP 6.43275
410 2XTN GTP 6.43275
411 2OFW ADX 6.43275
412 3ZL8 ADP 6.43275
413 2GAG NAD 6.43275
414 1OIX GDP 6.43275
415 1Q19 SSC 6.43275
416 4C4P GNP 6.43275
417 2UUU FAD 6.43275
418 3IAE D7K 6.43275
419 3RWO GDP 6.43275
420 4LX0 BEF GDP 6.43275
421 6BSX GDP 6.43275
422 4UA3 COA 6.43275
423 1YZN GNP 6.43275
424 1V0C ACO 6.43564
425 1V0C KNC 6.43564
426 1U8Z GDP 6.54762
427 2D7C GTP 6.58683
428 5FVJ ACO 6.62651
429 2ZTS ADP 6.77291
430 2CDN ADP 7.01754
431 2PZE ATP 7.01754
432 1LVK MNT BEF 7.01754
433 4WZ6 ATP 7.01754
434 3UIE ANP 7.01754
435 1S3G AP5 7.01754
436 1W7J ADP BEF 7.01754
437 4MKF AP5 7.01754
438 1OXV ANP 7.01754
439 3DOE GTP 7.01754
440 3EWA ANP 7.01754
441 1Z0F GDP 7.01754
442 5FHD ADP ALF 7.01754
443 5EXT ADP 7.01754
444 5CK5 GDP 7.01754
445 5LTJ ADP 7.01754
446 4OHY ANP 7.01754
447 3VMF GTP 7.01754
448 6BC0 GSP 7.01754
449 1XX6 ADP 7.01754
450 1G7S GDP 7.01754
451 5LTJ BEF 7.01754
452 1S8F GDP 7.01754
453 4D0N GDP 7.01754
454 2XAU ADP 7.01754
455 5GOE GDP 7.01754
456 5W76 GDP 7.01754
457 3BFV ADP 7.01754
458 5FTB ANP 7.01754
459 4YS0 ADP 7.01754
460 2CE7 ADP 7.01754
461 4P8K 38C 7.01754
462 4P8K FAD 7.01754
463 6CS8 F9Y 7.01754
464 3DEF GDP 7.01754
465 1WDT GTP 7.01754
466 4C12 ADP 7.01754
467 1FNN ADP 7.01754
468 4ZG4 VO4 ADP 7.01754
469 4HUT ATP 7.01754
470 1NJF ADP 7.01754
471 1NJF AGS 7.01754
472 3ITJ CIT 7.01754
473 2Q4W FAD 7.01754
474 2GCO GNP 7.01754
475 2B4B COA 7.01754
476 1AQU A3P 7.01754
477 1UKG MMA 7.01754
478 4D0G GTP 7.01754
479 5ZB0 ADP 7.01754
480 5ZB0 TYD 7.01754
481 1Q8V MAN MAN 7.01754
482 5XC5 GTP 7.01754
483 2B4D COA 7.01754
484 1BOB ACO 7.01754
485 1Q8O MAN MMA 7.01754
486 1CXZ GSP 7.01754
487 2ZEJ GDP 7.01754
488 2GCN GDP 7.01754
489 5BW4 SAM 7.01754
490 1IWE IMP 7.01754
491 1UKZ ADP 7.01754
492 3MJH GTP 7.14286
493 4KVG GTP 7.14286
494 3X1Z GNP 7.18563
495 2DT9 THR 7.18563
496 1KK8 BEF ADP 7.19424
497 3Q72 GNP 7.22892
498 1F2U ATP 7.38255
499 2IYL GDP 7.39437
500 5MVR ADP 7.40741
501 1KO8 6PG 7.42857
502 4U00 ADP 7.60234
503 2RGX AP5 7.60234
504 2OG2 MLI 7.60234
505 5G41 AP5 7.60234
506 5G3Y ADP 7.60234
507 1ZIN AP5 7.60234
508 2BIF ANP 7.60234
509 2BIF SIN 7.60234
510 4MKG AP5 7.60234
511 3B9Q MLI 7.60234
512 1SVK ALF GDP 7.60234
513 6AU6 GDP 7.60234
514 6CRK GDP 7.60234
515 1YRB GDP 7.60234
516 1GP2 GDP 7.60234
517 3FVQ ATP 7.60234
518 1RJ9 GCP 7.60234
519 1GOT GDP 7.60234
520 2F3R G5P 7.60234
521 2Q2Y ADP 7.60234
522 2Q2Y MKR 7.60234
523 3CPJ GDP 7.60234
524 6DEF GCP 7.60234
525 2XTZ GSP 7.60234
526 2ODE ALF GDP 7.60234
527 1BH2 GSP 7.60234
528 1D2E GDP 7.60234
529 2IS6 ADP 7.60234
530 1TAD ALF 7.60234
531 1TAD GDP 7.60234
532 1SKQ GDP 7.60234
533 1DS6 GDP 7.60234
534 2OM2 GDP 7.60234
535 1CR1 TTP 7.60234
536 5M7P ADP 7.60234
537 5HH0 COA 7.60234
538 2VHJ ADP 7.60234
539 5HGZ ACO 7.60234
540 1Q20 A3P 7.60234
541 1Q20 PLO 7.60234
542 1WY7 SAH 7.60234
543 1Y3A GDP 7.60234
544 1IHU ADP 7.60234
545 5ERG SAM 7.60234
546 5L3R GCP 7.60234
547 1UM0 FMN 7.60234
548 1IHU AF3 7.60234
549 1FQK GDP 7.60234
550 1TU3 GNP 7.60234
551 1FQJ GDP 7.60234
552 2WA2 SAM 7.60234
553 1J99 AND 7.60234
554 1R2Q GNP 7.64706
555 3PQC GDP 7.69231
556 4V0K GDP 7.69231
557 2HIM ASN 7.82123
558 1I1D COA 8.07453
559 1I1D 16G 8.07453
560 4BQS ADP 8.18713
561 4BQS K2Q 8.18713
562 4KFU ACP 8.18713
563 1NN5 ANP 8.18713
564 1NN5 2DT 8.18713
565 3MD0 GDP 8.18713
566 3BOS CDP 8.18713
567 1Z0A GDP 8.18713
568 5YT0 GDP 8.18713
569 5L3V GDP 8.18713
570 5IRN ADP 8.18713
571 2A5J GDP 8.18713
572 5KSZ GCP 8.18713
573 1G41 ADP 8.18713
574 3KTA AP5 8.18713
575 3SFV GDP 8.18713
576 3LXR GDP 8.18713
577 2I4I AMP 8.18713
578 1N62 FAD 8.18713
579 5EP2 AZU 8.18713
580 1Z06 GNP 8.18713
581 4QRH 0O2 8.18713
582 2FXV 5GP 8.18713
583 2C77 GNP 8.18713
584 4R2I ANP 8.18713
585 6GAS FAD 8.18713
586 5YGE ACO 8.18713
587 5YGE GLU 8.18713
588 3TKL GTP 8.18713
589 2HF9 GSP 8.18713
590 1JGT APC 8.18713
591 2C78 GNP 8.18713
592 1JGT CMA 8.18713
593 1XEX ATP 8.18713
594 3VYW SAM 8.18713
595 1Z0J GTP 8.23529
596 1YVD GNP 8.28402
597 1ZUI SKM 8.33333
598 5XKT GNP 8.5
599 1LVG ADP 8.77193
600 4BFW ZVW 8.77193
601 4CVN ADP 8.77193
602 1YQT ADP 8.77193
603 5YV5 ADP 8.77193
604 6B8B ADP 8.77193
605 4HAT GNP 8.77193
606 1WA5 GTP 8.77193
607 5VHC BEF ADP 8.77193
608 3GJ4 GDP 8.77193
609 3GJ0 GDP 8.77193
610 3GJ7 GDP 8.77193
611 2CBZ ATP 8.77193
612 1CS4 GSP 8.77193
613 1R0X ATP 8.77193
614 3T12 GDP ALF 8.77193
615 5BXQ GDP 8.77193
616 4HSE ADP 8.77193
617 1MKY GDP 8.77193
618 6FAA ADP 8.77193
619 5OEC GDP 8.77193
620 3T1O GDP 8.77193
621 4AUT FAD 8.77193
622 5H7J GCP 8.77193
623 5I0H ADP BEF 8.77193
624 2G77 GDP 8.77193
625 5X40 ACP 8.77193
626 2ZPT A3P 8.77193
627 6AIC AMP 8.77193
628 4ITM ATP 8.77193
629 2G77 AF3 8.77193
630 5G3U FDA 8.77193
631 2JEV NHQ 8.77193
632 2Q8M AMP 8.77193
633 1N71 COA 8.77193
634 6CUZ FEV 8.77193
635 2JB2 FAD 8.77193
636 2JB2 PHE 8.77193
637 5G5G FAD 8.77193
638 1D2N ANP 8.77193
639 6AMI TRP 8.77193
640 2O0J ADP 8.77193
641 1IBR GNP 8.77193
642 1HTW ADP 8.86076
643 3GJ3 GDP 9.09091
644 5H68 AGS 9.11765
645 1D5C GDP 9.25926
646 3FB4 AP5 9.35672
647 1JI0 ATP 9.35672
648 1G6O ADP 9.35672
649 5N69 ADP 9.35672
650 5BN3 ADP 9.35672
651 1FZQ GDP 9.35672
652 5HCN GCP 9.35672
653 3CNL GNP 9.35672
654 1YZG GDP 9.35672
655 1ZJ6 G3D 9.35672
656 6C90 ADP 9.35672
657 2AJ4 ANP 9.35672
658 2D2F ADP 9.35672
659 1Z0K GTP 9.35672
660 4GOJ GNP 9.35672
661 4ZI2 GNP 9.35672
662 3WR7 COA 9.35672
663 3L6C MLI 9.35672
664 4R57 ACO 9.35672
665 2PZM UDP 9.35672
666 2PZM NAD 9.35672
667 2BME GNP 9.35672
668 4NSQ COA 9.35672
669 3F8K COA 9.375
670 3RAB GNP 9.46746
671 4Y7U 2KH 9.52381
672 1CM0 COA 9.52381
673 5DI3 GNP 9.72973
674 4H1V GNP 9.7561
675 6BCA GSP 9.93377
676 1JJ7 ADP 9.94152
677 3NHB ADP 9.94152
678 3B5J 12D 9.94152
679 3M1I GTP 9.94152
680 3WYF GTP 9.94152
681 3WYG GTP 9.94152
682 2QEN ADP 9.94152
683 2GJ8 ALF GDP 9.94152
684 3AQ4 GDP 9.94152
685 4A4Z ANP 9.94152
686 4YLG GDP 9.94152
687 1Z6T ADP 9.94152
688 2IXE ATP 9.94152
689 1T8U UAP SGN IDS SGN 9.94152
690 1W78 PD8 9.94152
691 1W78 ADP 9.94152
692 1T8U A3P 9.94152
693 4IV9 FAD 9.94152
694 5MW4 5JU 9.94152
695 5E5U MLI 9.94152
696 1FFU FAD 9.94152
697 3BD9 A3P 9.94152
698 4B47 GDP 10.1928
699 1O3Y GTP 10.241
700 1J2J GTP 10.241
701 2AWN ADP 10.5263
702 1AKY AP5 10.5263
703 2HT6 GDP 10.5263
704 4HDO GNP 10.5263
705 1MR3 G3D 10.5263
706 4HDQ GNP 10.5263
707 4JLV ADP 10.5263
708 3RLF ANP 10.5263
709 1T3Q MCN 10.5263
710 1Q3Q ANP 10.5263
711 3FV1 DYH 10.5263
712 5CMK GLU 10.5263
713 4QC6 30N 10.6145
714 1W4R TTP 10.7692
715 4X8O AP5 11.1111
716 3IIJ ADP 11.1111
717 2GKS ADP 11.1111
718 3TNF GNP 11.1111
719 2FJU GSP 11.1111
720 5L3W GDP 11.1111
721 5Y6N ADP 11.1111
722 2D7D ADP 11.1111
723 1YTM ATP 11.1111
724 2R42 FPS 11.1111
725 3KJI ADP 11.1111
726 5VGR GDP 11.1111
727 5L3S GNP 11.1111
728 2A2C NG1 11.1111
729 2A2C ADP 11.1111
730 2EW1 GNP 11.1111
731 5TS5 FAD 11.1111
732 4LHW GNP 11.1111
733 3QBT GNP 11.1111
734 3OU2 SAH 11.1111
735 5L3S G 11.1111
736 1G16 GDP 11.1765
737 2ZFZ ARG 11.3924
738 4YMU ATP 11.6959
739 1Z83 AP5 11.6959
740 4WZA ADP 11.6959
741 4WZA ACP 11.6959
742 1OS1 ATP 11.6959
743 1OS1 PYR 11.6959
744 1OFH ADP 11.6959
745 1PUJ GNP 11.6959
746 3E70 GDP 11.6959
747 1NRJ GTP 11.6959
748 2GQT FAD 11.6959
749 5LLB 6YZ 11.6959
750 5LS7 ACO 11.7647
751 5GK9 ACO 12
752 2W58 ADP 12.2807
753 5UWO GNP 12.2807
754 5UWP GNP 12.2807
755 5UWU GNP 12.2807
756 5UWQ GNP 12.2807
757 5UWS GNP 12.2807
758 5DI9 GNP 12.2807
759 2V7Q ATP 12.2807
760 1NF3 GNP 12.2807
761 4YC7 GNP 12.2807
762 2NGR GDP 12.2807
763 2CK3 ANP 12.2807
764 1W0J ADP 12.2807
765 1W0J ADP BEF 12.2807
766 2V7Q ADP 12.2807
767 2WMO GTP 12.2807
768 2CK3 ADP 12.2807
769 1A4R GNH 12.2807
770 1A4R GDP 12.2807
771 1GRN GDP 12.2807
772 4ITR GDP 12.2807
773 4QDI ATP 12.2807
774 6CIT GNP 12.2807
775 5UWH GNP 12.2807
776 5DIF GNP 12.2807
777 5DHF GNP 12.2807
778 5UWW GNP 12.2807
779 5UWI GNP 12.2807
780 5UWT GNP 12.2807
781 5UWR GNP 12.2807
782 5UWJ GNP 12.2807
783 4CRZ ACO 12.5874
784 5UQW GDP 12.6984
785 2ZFI ADP 12.8655
786 1U0J ADP 12.8655
787 6B4K ANP 12.8655
788 2Z5F A3P 12.8655
789 6EDV COA 12.8655
790 1L3I SAH 12.8655
791 1B1C FMN 12.8655
792 2W83 GTP 12.987
793 4IEE AGS 13.4503
794 1XKV ATP 13.4503
795 3TBK ANP 13.4503
796 2V2V V12 13.4503
797 5IRR GSP 13.4503
798 1EK0 GNP 13.5294
799 1LFD GNP 13.7725
800 3DDC GNP 13.8554
801 6FA4 GNP 13.8728
802 3H4S ADP 14.0351
803 4AG5 ADP 14.0351
804 4FRZ ADP 14.0351
805 3TK1 GDP 14.0351
806 5OCG GNP 14.0351
807 1E96 GTP 14.0351
808 5KUT GDP 14.0351
809 2WIC GNP 14.0351
810 2EFE GNH 14.0351
811 4R98 GNH 14.0351
812 4H8N NDP 14.0351
813 2HV8 GTP 14.0625
814 1UAD GNP 14.1414
815 5O2T GSP 14.2012
816 6D55 GNP 14.3713
817 6D5L GNP 14.3713
818 6D56 GNP 14.3713
819 6D5M GNP 14.3713
820 6D59 GNP 14.3713
821 6D5J GNP 14.3713
822 6D5E GNP 14.3713
823 6BVJ GNP 14.3713
824 6BVK GNP 14.3713
825 6D5V GNP 14.3713
826 6D5G GNP 14.3713
827 6BVM GNP 14.3713
828 6BVL GNP 14.3713
829 6D5H GNP 14.3713
830 6BVI GNP 14.3713
831 1CLU DBG 14.4578
832 2UZI GTP 14.4578
833 1NVV GNP 14.4578
834 5WLB GNP 14.4578
835 1WQ1 AF3 14.4578
836 1WQ1 GDP 14.4578
837 2X7I CIT 14.6199
838 3AB3 GDP 14.6199
839 4R6W SAH 14.6199
840 1ZCB GDP 14.6199
841 3GJX GTP 15.2047
842 3WXM GTP 15.2047
843 3EC1 GDP 15.2047
844 3R96 ACO 15.2047
845 3R96 AMP 15.2047
846 1QHG ATP 15.2047
847 1W5T ADP 15.2047
848 1W5T ANP 15.2047
849 1G55 SAH 15.2047
850 3CH5 GDP 15.3846
851 1QHH ATP 15.5689
852 2C5L GTP 15.6069
853 1XMV ADP 15.7895
854 5TB5 GDP 15.7895
855 4IDN GNP 15.7895
856 5TAR GDP 15.7895
857 3T5G GDP 15.7895
858 1G4U GDP 15.7895
859 4YRY FAD 15.7895
860 4K81 GTP 15.7895
861 5Z54 0HZ 15.7895
862 5E95 GDP 16.0714
863 3CX8 GSP 16.3743
864 1K6M AGS 16.3743
865 3H86 AP5 16.3743
866 5H67 ATP 16.3743
867 1PS9 FAD 16.3743
868 1UPT GTP 16.6667
869 2VB6 ADP BEF 16.7785
870 2J9C ATP 16.8067
871 1P72 ADP 16.9591
872 5WDR GNP 16.9591
873 1I9G SAM 16.9591
874 1Z08 GNP 16.9591
875 4NU0 AP5 17.5439
876 4NON GDP 17.5439
877 1J0D 5PA 17.5439
878 3GJ5 GDP 17.6471
879 1L2T ATP 18.1287
880 2QN6 GDP 18.2796
881 1OE0 TTP 19.2982
882 4DID GDP 19.7368
883 1GUA GNP 19.7531
884 4TL6 ANP 19.883
885 3VX3 ADP 19.883
886 3ZIA ATP 20.6349
887 3ZIA ADP 20.6349
888 3KUD GDP 20.9877
889 1E2K TMC 21.0526
890 2J59 GTP 22.0238
891 2FSH ANP 22.2222
892 6BCB GSP 22.6027
893 1X1R GDP 25.8427
894 3E5H GNP 26.3158
895 3Q85 GNP 27.2189
896 1GXU 2HP 27.4725
897 4KVA GTP 27.4854
898 3GJ8 GDP 28.2609
899 3BC1 GNP 28.8136
900 4D9C PMP 29.2398
901 1S9D GDP 29.878
902 1RE0 GDP 29.878
903 5AK0 8V1 30.4094
904 1SVI GDP 30.4094
905 5KDO GDP 31.0811
906 5HR5 ADP 31.5789
907 2QG6 NMN 33.3333
908 3A4M ADP 35.0877
909 5UPK GNP 35.4167
910 1R4A GNP 37.2549
911 1QF9 ALF 38.5965
912 1QF9 ADP 38.5965
913 1QF9 C5P 38.5965
Pocket No.: 2; Query (leader) PDB : 4QM7; Ligand: GTP; Similar sites found with APoc: 18
This union binding pocket(no: 2) in the query (biounit: 4qm7.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 3LEK BCW None
2 2B99 RDL 2.92398
3 4JD3 COA 2.92398
4 3X0V FAD 4.67836
5 3E4O SIN 4.67836
6 2VVL FAD 4.67836
7 5NDB 8TW 5.84795
8 2UUU PL3 6.43275
9 3WCA FPS 6.43275
10 1M4I KAN 7.60234
11 1M4I COA 7.60234
12 4R74 F6P 7.60234
13 1M4I PAP 7.60234
14 6AM8 PLT 8.77193
15 3GGO ENO 9.35672
16 3GGO NAI 9.35672
17 5J3R GSH 10.5263
18 3QDK QDK 11.1111
APoc FAQ
Feedback