Receptor
PDB id Resolution Class Description Source Keywords
4QFX 2.2 Å EC: 3.1.5.- CRYSTAL STRUCTURE OF THE TETRAMERIC DGTP/DATP-BOUND SAMHD1 ( MUTANT CATALYTIC CORE HOMO SAPIENS DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE 2-prime -DEOXYNU5-prime -TRIPHOSPHATE HIV RESTRICTION FACTOR DNTPASE HYDROLASE
Ref.: STRUCTURAL BASIS OF ALLOSTERIC ACTIVATION OF STERIL MOTIF AND HISTIDINE-ASPARTATE DOMAIN-CONTAINING PRO (SAMHD1) BY NUCLEOSIDE TRIPHOSPHATES. J.BIOL.CHEM. V. 289 32617 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DGT C:703;
A:704;
A:701;
B:701;
D:702;
B:702;
C:702;
A:702;
 Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
none;
none;
none;
none;
 submit data
507.181 C10 H16 N5 O13 P3 c1nc2...
DTP A:703;
B:703;
D:701;
C:701;
 Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
 submit data
491.182 C10 H16 N5 O12 P3 c1nc(...
MG A:707;
B:704;
A:705;
C:704;
D:703;
C:705;
A:706;
C:706;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
 submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6XU1 2.2 Å EC: 3.1.5.- CRYSTAL STRUCTURE OF TETRAMERIC HUMAN H215A-SAMHD1 (RESIDUES WITH GTP, DAMPNPP AND MG HOMO SAPIENS TRIPHOSPHOHYDROLASE METALLO-ENZYME BINUCLEAR HD HYDROLAS
Ref.: CRYSTAL STRUCTURES OF SAMHD1 INHIBITOR COMPLEXES RE MECHANISM OF WATER-MEDIATED DNTP HYDROLYSIS. NAT COMMUN V. 11 3165 2020
Members (33)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4QFX - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
2 6TXF - DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
3 6DW4 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 6TX0 - DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
5 4BZB - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
6 4TO6 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
7 4RXQ - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
8 6DW7 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
9 4QFY - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
10 4MZ7 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
11 4TNX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
12 4RXP - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
13 4QG4 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
14 4TO4 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
15 6DWD - HDV C11 H17 F N5 O12 P3 Cc1nc(c2c(....
16 6DW5 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
17 4ZWG - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
18 4TNZ - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
19 4RXR - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
20 4RXS - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
21 4TO2 - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
22 6CM2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
23 6DWJ - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
24 6DW3 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
25 4TO3 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
26 6DWK - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
27 4QG0 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
28 4TO0 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
29 4QG2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
30 6XU1 Ki = 0.78 uM DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
31 4QG1 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
32 4TNP - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
33 4QFZ - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
70% Homology Family (33)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4QFX - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
2 6TXF - DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
3 6DW4 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 6TX0 - DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
5 4BZB - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
6 4TO6 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
7 4RXQ - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
8 6DW7 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
9 4QFY - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
10 4MZ7 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
11 4TNX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
12 4RXP - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
13 4QG4 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
14 4TO4 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
15 6DWD - HDV C11 H17 F N5 O12 P3 Cc1nc(c2c(....
16 6DW5 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
17 4ZWG - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
18 4TNZ - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
19 4RXR - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
20 4RXS - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
21 4TO2 - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
22 6CM2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
23 6DWJ - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
24 6DW3 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
25 4TO3 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
26 6DWK - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
27 4QG0 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
28 4TO0 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
29 4QG2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
30 6XU1 Ki = 0.78 uM DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
31 4QG1 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
32 4TNP - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
33 4QFZ - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
50% Homology Family (33)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4QFX - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
2 6TXF - DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
3 6DW4 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 6TX0 - DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
5 4BZB - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
6 4TO6 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
7 4RXQ - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
8 6DW7 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
9 4QFY - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
10 4MZ7 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
11 4TNX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
12 4RXP - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
13 4QG4 - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
14 4TO4 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
15 6DWD - HDV C11 H17 F N5 O12 P3 Cc1nc(c2c(....
16 6DW5 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
17 4ZWG - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
18 4TNZ - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
19 4RXR - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
20 4RXS - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
21 4TO2 - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
22 6CM2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
23 6DWJ - DTP C10 H16 N5 O12 P3 c1nc(c2c(n....
24 6DW3 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
25 4TO3 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
26 6DWK - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
27 4QG0 - DGT C10 H16 N5 O13 P3 c1nc2c(n1[....
28 4TO0 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
29 4QG2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
30 6XU1 Ki = 0.78 uM DZ4 C10 H17 N6 O11 P3 c1nc(c2c(n....
31 4QG1 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
32 4TNP - DCP C9 H16 N3 O13 P3 C1[C@@H]([....
33 4QFZ - TTP C10 H17 N2 O14 P3 CC1=CN(C(=....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: DGT; Similar ligands found: 97
No: Ligand ECFP6 Tc MDL keys Tc
1 DGT 1 1
2 DGI 0.897436 1
3 DGP 0.775 0.986842
4 DG 0.775 0.986842
5 GH3 0.673913 0.948052
6 GTP 0.659341 0.923077
7 0O2 0.622449 0.935065
8 CGP 0.6 0.914634
9 GP3 0.597826 0.9
10 GDP 0.591398 0.923077
11 GSP 0.561224 0.878049
12 G3D 0.561224 0.935065
13 DTP 0.557895 0.909091
14 HF7 0.556701 0.897436
15 GAV 0.55 0.888889
16 G4P 0.55 0.935065
17 GNH 0.536082 0.911392
18 G1R 0.535354 0.911392
19 G2R 0.533981 0.961538
20 9GM 0.53 0.9
21 GNP 0.53 0.9
22 G 0.521277 0.910256
23 5GP 0.521277 0.910256
24 GCP 0.52 0.924051
25 GPX 0.514563 0.922078
26 GPD 0.513514 0.902439
27 G5P 0.509091 0.9
28 GTG 0.504587 0.86747
29 G2P 0.5 0.936709
30 G3A 0.5 0.9
31 GKE 0.495413 0.888889
32 GDD 0.495413 0.888889
33 GDC 0.495413 0.888889
34 GMV 0.49505 0.9
35 DI 0.494737 0.960526
36 6CK 0.486486 0.86747
37 DAT 0.484536 0.909091
38 Y9Z 0.481818 0.880952
39 GP2 0.48 0.936709
40 JB2 0.477876 0.888889
41 GFB 0.477477 0.888889
42 GDR 0.477477 0.888889
43 QBQ 0.475248 0.910256
44 GPG 0.472222 0.888889
45 2GP 0.46875 0.935065
46 3GP 0.46875 0.897436
47 ALF 5GP 0.466019 0.823529
48 GKD 0.464912 0.888889
49 BGO 0.462185 0.878049
50 8DG 0.461538 0.857143
51 GDP BEF 0.461538 0.864198
52 GDX 0.46087 0.9
53 P2G 0.459184 0.860759
54 GTP MG 0.457143 0.886076
55 MGP 0.456311 0.888889
56 JB3 0.453782 0.878049
57 GDP ALF 0.453704 0.823529
58 6G0 0.451923 0.888889
59 CAG 0.451613 0.818182
60 GMP 0.450549 0.810127
61 P1G 0.45 0.873418
62 NGD 0.45 0.888889
63 YGP 0.446429 0.835294
64 3PD UM3 0.446281 0.86747
65 G1G 0.444444 0.857143
66 GDP AF3 0.440367 0.823529
67 F6G 0.44 0.8375
68 N5P 0.439252 0.75
69 DUT 0.438776 0.7875
70 01G 0.433628 0.903614
71 C1Z 0.432432 0.935065
72 TPG 0.430769 0.782609
73 DCP 0.43 0.848101
74 CF2 0.428571 0.802326
75 GGM 0.427419 0.857143
76 2MD 0.427419 0.827586
77 U2G 0.42623 0.86747
78 CZF 0.423077 0.860759
79 CG2 0.419355 0.86747
80 KB7 0.419048 0.785714
81 MGD 0.417323 0.827586
82 TTP 0.415842 0.759036
83 MD1 0.415385 0.848837
84 PGD 0.415385 0.857143
85 FEG 0.414634 0.858824
86 ZGP 0.41129 0.848837
87 3AT 0.409524 0.871795
88 DDS 0.409524 0.858974
89 DBG 0.409091 0.878049
90 3ZE 0.407767 0.886076
91 6U4 0.407407 0.853659
92 GDP 7MG 0.40678 0.843373
93 GPC 0.40625 0.816092
94 523 0.403846 0.788235
95 SGP 0.401961 0.807229
96 7D4 0.401961 0.814815
97 AGO 0.401575 0.86747
Ligand no: 2; Ligand: DTP; Similar ligands found: 187
No: Ligand ECFP6 Tc MDL keys Tc
1 DTP 1 1
2 DAT 0.891892 1
3 DA 0.773333 0.971831
4 D5M 0.773333 0.971831
5 DZ4 0.705882 0.972603
6 AS 0.696203 0.92
7 DDS 0.694118 0.944444
8 HF7 0.689655 0.986111
9 3AT 0.655172 0.931507
10 7D4 0.635294 0.893333
11 ATP 0.627907 0.905405
12 HEJ 0.627907 0.905405
13 3D1 0.626667 0.835616
14 3L1 0.626667 0.835616
15 AQP 0.62069 0.905405
16 5FA 0.62069 0.905405
17 CPA 0.584906 0.8625
18 ZDA 0.577778 0.853333
19 B4P 0.574713 0.88
20 AP5 0.574713 0.88
21 CUU 0.573034 0.931507
22 5F1 0.56962 0.794521
23 BA3 0.563218 0.88
24 DGT 0.557895 0.909091
25 ADP 0.556818 0.905405
26 101 0.552941 0.917808
27 7D3 0.551724 0.893333
28 A2D 0.54023 0.88
29 6MA 0.539326 0.931507
30 DOI 0.539326 0.917808
31 2A5 0.532609 0.932432
32 6YZ 0.53125 0.906667
33 25L 0.529412 0.893333
34 PAP 0.526882 0.917808
35 AGS 0.526882 0.858974
36 ATR 0.526882 0.930556
37 T99 0.515789 0.87013
38 TAT 0.515789 0.87013
39 103 0.505747 0.826667
40 AN2 0.5 0.893333
41 AT4 0.5 0.87013
42 APR 0.5 0.88
43 AR6 0.5 0.88
44 ACQ 0.5 0.906667
45 A3R 0.49505 0.921053
46 A1R 0.49505 0.921053
47 AD9 0.494737 0.881579
48 M33 0.494624 0.868421
49 AV2 0.489796 0.88
50 ACP 0.489362 0.906667
51 A 0.488636 0.878378
52 AMP 0.488636 0.878378
53 7D5 0.488372 0.866667
54 T5A 0.486957 0.853659
55 NA7 0.485437 0.945946
56 DGI 0.484536 0.909091
57 ANP 0.484536 0.881579
58 128 0.482143 0.747126
59 HQG 0.48 0.893333
60 A2R 0.48 0.893333
61 CA0 0.478723 0.857143
62 ADX 0.478723 0.795181
63 A22 0.475248 0.893333
64 HDV 0.474747 0.881579
65 JSQ 0.474227 0.858974
66 HFD 0.474227 0.858974
67 KG4 0.473684 0.857143
68 45A 0.472527 0.831169
69 ABM 0.472527 0.831169
70 PRX 0.46875 0.833333
71 APC 0.46875 0.92
72 ADQ 0.466019 0.857143
73 PPS 0.464646 0.817073
74 ITT 0.463158 0.853333
75 6OG 0.463158 0.907895
76 A3P 0.462366 0.90411
77 A2P 0.462366 0.916667
78 ATF 0.46 0.87013
79 50T 0.458333 0.868421
80 N5P 0.456311 0.797468
81 4AD 0.451923 0.883117
82 AMP MG 0.450549 0.84
83 8LE 0.45 0.8125
84 5AL 0.45 0.844156
85 3OD 0.448598 0.857143
86 JNT 0.447619 0.906667
87 A12 0.446809 0.92
88 AP2 0.446809 0.92
89 QA7 0.446602 0.8125
90 G5P 0.446429 0.8375
91 A4P 0.444444 0.790698
92 UP5 0.443478 0.835443
93 OAD 0.443396 0.857143
94 9X8 0.443396 0.835443
95 MDR 0.44186 0.783784
96 SRP 0.441176 0.87013
97 8LH 0.441176 0.822785
98 7DT 0.438776 0.891892
99 ADP BEF 0.4375 0.853333
100 ADP MG 0.4375 0.853333
101 G3A 0.4375 0.8375
102 AP0 0.435897 0.814815
103 NB8 0.435185 0.860759
104 SRA 0.434783 0.833333
105 APC MG 0.434343 0.855263
106 DLL 0.433962 0.844156
107 00A 0.433962 0.802469
108 2AM 0.433333 0.90411
109 AU1 0.43299 0.881579
110 DCP 0.43299 0.831169
111 8LQ 0.432692 0.846154
112 6V0 0.431034 0.814815
113 NAI 0.431034 0.825
114 GTA 0.429825 0.807229
115 3AM 0.428571 0.864865
116 OOB 0.428571 0.844156
117 8QN 0.428571 0.844156
118 OZV 0.428571 0.88
119 5SV 0.428571 0.814815
120 25A 0.428571 0.88
121 9SN 0.427273 0.792683
122 WAQ 0.425926 0.871795
123 PR8 0.425926 0.8625
124 V3L 0.425743 0.88
125 NDP 0.425 0.8375
126 139 0.425 0.8625
127 AMO 0.424528 0.894737
128 PAJ 0.424528 0.804878
129 KMQ 0.423423 0.846154
130 PTJ 0.422018 0.814815
131 FYA 0.422018 0.893333
132 1ZZ 0.422018 0.807229
133 BIS 0.422018 0.848101
134 NZQ 0.421488 0.85
135 ADV 0.42 0.894737
136 ADP PO3 0.42 0.853333
137 ATP MG 0.42 0.853333
138 RBY 0.42 0.894737
139 OVE 0.419355 0.868421
140 MAP 0.419048 0.858974
141 GGZ 0.419048 0.792683
142 TXD 0.418803 0.848101
143 3AD 0.418605 0.77027
144 VO4 ADP 0.417476 0.857143
145 ALF ADP 0.417476 0.790123
146 ANP MG 0.417476 0.844156
147 KF5 0.416667 0.635135
148 3UK 0.416667 0.833333
149 BEF ADP 0.415842 0.831169
150 TXE 0.415254 0.848101
151 0WD 0.414634 0.8375
152 12D 0.413793 0.755814
153 LAD 0.412844 0.85
154 B5V 0.412844 0.822785
155 GAP 0.411765 0.810127
156 2FD 0.411111 0.805195
157 FA5 0.410714 0.87013
158 48N 0.410256 0.8375
159 CNA 0.409836 0.87013
160 TXP 0.409836 0.860759
161 PUA 0.409449 0.897436
162 TXA 0.409091 0.846154
163 ME8 0.409091 0.807229
164 AFH 0.408696 0.82716
165 DGP 0.408163 0.896104
166 SON 0.408163 0.894737
167 DG 0.408163 0.896104
168 V2G 0.407767 0.860759
169 AHX 0.407407 0.860759
170 NAX 0.40678 0.839506
171 DND 0.40678 0.846154
172 NJP 0.406504 0.858974
173 DAL AMP 0.40566 0.820513
174 DQV 0.405172 0.868421
175 7D7 0.404762 0.733333
176 OMR 0.403361 0.819277
177 GH3 0.401869 0.858974
178 LAQ 0.401709 0.807229
179 NPW 0.401639 0.851852
180 ADS THS THS THS 0.401575 0.770115
181 XYA 0.4 0.76
182 RAB 0.4 0.76
183 F6G 0.4 0.797468
184 CL9 0.4 0.805195
185 J4G 0.4 0.883117
186 L3W 0.4 0.846154
187 ADN 0.4 0.76
Similar Ligands (3D)
Ligand no: 1; Ligand: DGT; Similar ligands found: 24
No: Ligand Similarity coefficient
1 HDV 0.9878
2 DZ4 0.9790
3 JSQ 0.9693
4 HFD 0.9578
5 HEJ 0.9531
6 ANP 0.9413
7 AGS 0.9355
8 ATP 0.9177
9 ACP 0.9114
10 ADP BEF 0.9102
11 ADP ALF 0.9081
12 MGT 0.9047
13 HF4 0.9026
14 APC 0.9014
15 ALF ADP 0.8890
16 2KH 0.8809
17 UTP 0.8773
18 8GD 0.8707
19 ADP 0.8685
20 SAM 0.8665
21 8QN 0.8658
22 CTP 0.8611
23 BEF ADP 0.8591
24 IDP 0.8537
Ligand no: 2; Ligand: DTP; Similar ligands found: 32
No: Ligand Similarity coefficient
1 TTP 0.9873
2 GNP 0.9719
3 GTP 0.9699
4 GSP 0.9655
5 GDP BEF 0.9613
6 BEF GDP 0.9585
7 GCP 0.9553
8 GDP AF3 0.9521
9 DUT 0.9505
10 9GM 0.9499
11 ALF GDP 0.9474
12 GDP ALF 0.9469
13 DBG 0.9381
14 ADP ALF 0.9354
15 UTP 0.9313
16 CTP 0.9261
17 HF4 0.9191
18 ADP AF3 0.9091
19 GDP MG 0.8952
20 MGT 0.8868
21 SSA 0.8856
22 GNH 0.8843
23 GDP 0.8842
24 GTF 0.8819
25 DSZ 0.8793
26 SAM 0.8779
27 Y9Z 0.8743
28 D3T 0.8721
29 2KH 0.8700
30 A5A 0.8669
31 SAH 0.8653
32 IDP 0.8579
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 6xu1.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
2 2HEK GDP 36.9272
Pocket No.: 2; Query (leader) PDB : 6XU1; Ligand: GTP; Similar sites found with APoc: 2
This union binding pocket(no: 2) in the query (biounit: 6xu1.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
2 2HEK GDP 36.9272
Pocket No.: 3; Query (leader) PDB : 6XU1; Ligand: GTP; Similar sites found with APoc: 2
This union binding pocket(no: 3) in the query (biounit: 6xu1.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
2 2HEK GDP 36.9272
Pocket No.: 4; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: 2
This union binding pocket(no: 4) in the query (biounit: 6xu1.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
2 2HEK GDP 36.9272
Pocket No.: 5; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 6xu1.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 6XU1; Ligand: GTP; Similar sites found with APoc: 2
This union binding pocket(no: 6) in the query (biounit: 6xu1.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
2 2HEK GDP 36.9272
Pocket No.: 7; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: 2
This union binding pocket(no: 7) in the query (biounit: 6xu1.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
2 2HEK GDP 36.9272
Pocket No.: 8; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 6xu1.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 6xu1.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: 2
This union binding pocket(no: 10) in the query (biounit: 6xu1.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
2 2HEK GDP 36.9272
Pocket No.: 11; Query (leader) PDB : 6XU1; Ligand: GTP; Similar sites found with APoc: 2
This union binding pocket(no: 11) in the query (biounit: 6xu1.bio1) has 126 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
2 2HEK GDP 36.9272
Pocket No.: 12; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 6xu1.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 13; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 13) in the query (biounit: 6xu1.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 14; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 14) in the query (biounit: 6xu1.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 15; Query (leader) PDB : 6XU1; Ligand: GTP; Similar sites found with APoc: 1
This union binding pocket(no: 15) in the query (biounit: 6xu1.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
Pocket No.: 16; Query (leader) PDB : 6XU1; Ligand: GTP; Similar sites found with APoc: 1
This union binding pocket(no: 16) in the query (biounit: 6xu1.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
Pocket No.: 17; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 17) in the query (biounit: 6xu1.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 18; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 18) in the query (biounit: 6xu1.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 19; Query (leader) PDB : 6XU1; Ligand: GTP; Similar sites found with APoc: 1
This union binding pocket(no: 19) in the query (biounit: 6xu1.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
Pocket No.: 20; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 20) in the query (biounit: 6xu1.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 21; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 21) in the query (biounit: 6xu1.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 22; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 22) in the query (biounit: 6xu1.bio2) has 20 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 23; Query (leader) PDB : 6XU1; Ligand: DZ4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 23) in the query (biounit: 6xu1.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 24; Query (leader) PDB : 6XU1; Ligand: GTP; Similar sites found with APoc: 1
This union binding pocket(no: 24) in the query (biounit: 6xu1.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 2HEK GDP 36.9272
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