Receptor
PDB id Resolution Class Description Source Keywords
4PXQ 2.2 Å EC: 5.1.3.17 CRYSTAL STRUCTURE OF D-GLUCURONYL C5-EPIMERASE IN COMPLEX WI HEXASACCHARIDE DANIO RERIO EPIMERIZATION ENZYME MULTIPLE DOMAIN STRUCTURE HEPARAN SULEPIMERASE HEPARIN HEPARAN SULFATE ISOMERASE
Ref.: STRUCTURAL AND FUNCTIONAL STUDY OF D-GLUCURONYL C5-EPIMERASE. J.BIOL.CHEM. V. 290 4620 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
UAP SGN IDS SGN IDS SGN B:801;
A:801;
Valid;
Valid;
none;
none;
submit data
1720.31 n/a [S+2]...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4PXQ 2.2 Å EC: 5.1.3.17 CRYSTAL STRUCTURE OF D-GLUCURONYL C5-EPIMERASE IN COMPLEX WI HEXASACCHARIDE DANIO RERIO EPIMERIZATION ENZYME MULTIPLE DOMAIN STRUCTURE HEPARAN SULEPIMERASE HEPARIN HEPARAN SULFATE ISOMERASE
Ref.: STRUCTURAL AND FUNCTIONAL STUDY OF D-GLUCURONYL C5-EPIMERASE. J.BIOL.CHEM. V. 290 4620 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4PXQ - UAP SGN IDS SGN IDS SGN n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4PXQ - UAP SGN IDS SGN IDS SGN n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4PXQ - UAP SGN IDS SGN IDS SGN n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: UAP SGN IDS SGN IDS SGN; Similar ligands found: 17
No: Ligand ECFP6 Tc MDL keys Tc
1 SGN IDS UAP SGN IDS SGN 1 1
2 SGN IDS UAP SGN 1 1
3 UAP SGN IDS SGN IDS SGN 1 1
4 UAP SGN IDS SGN 1 1
5 UAP SGN IDS SGN IDS 0.839623 1
6 SGN IDS SGN IDS 0.72381 0.967742
7 SGN IDS SGN IDS SGN 0.66087 0.9375
8 SGN IDS SGN IDS SGN IDS 0.60177 0.952381
9 IDS SGN IDS SGN IDS 0.561983 0.952381
10 IDS SGN IDS SGN IDS IDS 0.548387 0.9375
11 IDS SGN IDS SGN IDS SUS IDS SGN 0.548387 0.952381
12 SGN IDY 0.495495 0.876923
13 IDU SGN 0.491071 0.904762
14 SGN IXD 0.491071 0.904762
15 NGY BDP SGN IDS SGN BDP 0.485507 0.895522
16 SUS IDY 0.448276 0.846154
17 GNS BDP GNS IDS GNS BDP NPO 0.431655 0.810811
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4PXQ; Ligand: UAP SGN IDS SGN IDS SGN; Similar sites found: 2
This union binding pocket(no: 1) in the query (biounit: 4pxq.bio1) has 29 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4X8D AVI 0.007027 0.44443 3.13199
2 3ZJQ NCA 0.02393 0.40038 4.10256
Pocket No.: 2; Query (leader) PDB : 4PXQ; Ligand: UAP SGN IDS SGN IDS SGN; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4pxq.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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