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Receptor
PDB id Resolution Class Description Source Keywords
4PSB 1.42 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF PHYTOHORMONE BINDING PROTEIN FROM VIGNA IN COMPLEX WITH GIBBERELLIC ACID (GA3) VIGNA RADIATA CYTOKININ SPECIFIC BINDING PROTEIN (CSBP) PR-10 FOLD GIBBECYTOKININ PLANT HORMONE BINDING PLANT PROTEIN
Ref.: SPECIFIC BINDING OF GIBBERELLIC ACID BY CYTOKININ-S BINDING PROTEINS: A NEW ASPECT OF PLANT HORMONE-BIN PROTEINS WITH THE PR-10 FOLD. ACTA CRYSTALLOGR.,SECT.D V. 70 2032 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GA3 A:201;
Valid;
none;
Kd = 23 uM
346.374 C19 H22 O6 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4PSB 1.42 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF PHYTOHORMONE BINDING PROTEIN FROM VIGNA IN COMPLEX WITH GIBBERELLIC ACID (GA3) VIGNA RADIATA CYTOKININ SPECIFIC BINDING PROTEIN (CSBP) PR-10 FOLD GIBBECYTOKININ PLANT HORMONE BINDING PLANT PROTEIN
Ref.: SPECIFIC BINDING OF GIBBERELLIC ACID BY CYTOKININ-S BINDING PROTEINS: A NEW ASPECT OF PLANT HORMONE-BIN PROTEINS WITH THE PR-10 FOLD. ACTA CRYSTALLOGR.,SECT.D V. 70 2032 2014
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 3C0V - ZEA C10 H13 N5 O C/C(=CCNc1....
2 2FLH Kd = 148 uM ZEA C10 H13 N5 O C/C(=CCNc1....
3 4PSB Kd = 23 uM GA3 C19 H22 O6 C[C@@]12[C....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 3C0V - ZEA C10 H13 N5 O C/C(=CCNc1....
2 2FLH Kd = 148 uM ZEA C10 H13 N5 O C/C(=CCNc1....
3 4PSB Kd = 23 uM GA3 C19 H22 O6 C[C@@]12[C....
4 4Q0K Kd = 13.4 uM GA3 C19 H22 O6 C[C@@]12[C....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 3C0V - ZEA C10 H13 N5 O C/C(=CCNc1....
2 2FLH Kd = 148 uM ZEA C10 H13 N5 O C/C(=CCNc1....
3 4PSB Kd = 23 uM GA3 C19 H22 O6 C[C@@]12[C....
4 4Q0K Kd = 13.4 uM GA3 C19 H22 O6 C[C@@]12[C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GA3; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 GA3 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4PSB; Ligand: GA3; Similar sites found with APoc: 194
This union binding pocket(no: 1) in the query (biounit: 4psb.bio1) has 34 residues
No: Leader PDB Ligand Sequence Similarity
1 5VGS 9A7 None
2 5VGS 9A4 None
3 5N1X 8HH None
4 5FPX GLY SER SER HIS HIS HIS HIS HIS None
5 5VKI THR NGA GAL NAG None
6 2YIP YIO None
7 1OGZ EQU None
8 5AIG VPR None
9 4ZU4 4TG None
10 3W21 AKG None
11 2AGC DAO None
12 1NWW HPN None
13 3BRN SRO None
14 2ARC ARA None
15 1OYJ GSH None
16 5HV0 AKG None
17 5EPQ OLA None
18 6GNO XDI None
19 4RW3 IPD None
20 2BOS GLA GAL GLC None
21 1SDW IYT None
22 4MZU TYD None
23 1FMB HYB None
24 3A51 VDY None
25 3M3E GAL A2G NPO 1.29032
26 3GFZ FMN 1.29032
27 5OO5 UUA 1.6129
28 1X8D RNS 1.92308
29 1I06 TZL 1.93548
30 5VX9 FUC GAL NAG GAL BGC 1.93548
31 4FHT DHB 1.93548
32 5H2D ERG 1.93548
33 2ET1 GLV 1.93548
34 3BMO AX4 1.93548
35 2CM4 RCL 2
36 5KEW 6SB 2.08333
37 1DTL BEP 2.58065
38 4L4J NAG NAG BMA MAN NAG 2.58065
39 5MWJ EBU 2.58065
40 4WGF HX2 2.58065
41 1SGJ OAA 2.58065
42 4OR7 25U 2.58065
43 5GP0 GPP 2.68456
44 4WVO 3UZ 3.22581
45 5UR6 8KM 3.22581
46 2OVD DAO 3.22581
47 2IUW AKG 3.22581
48 4D1J DGJ 3.22581
49 3TL1 JRO 3.22581
50 3N9P OGA 3.22581
51 5DGR GCS 3.22581
52 2YJD YJD 3.22581
53 1U3R 338 3.22581
54 4AZC NGW 3.22581
55 5HA0 LTD 3.22581
56 4QDC ASD 3.87097
57 4U0W 16G 3.87097
58 5U83 ZN8 3.87097
59 4P7X AKG 3.87097
60 4P7X YCP 3.87097
61 4L9I 8PR 3.87097
62 2P1E LAC 3.87097
63 4QCK ASD 3.87097
64 4LIT AKG 3.87097
65 5TBM 79A 4.34783
66 4JH6 FCN 4.34783
67 4N2R FUB 4.51613
68 1UMZ BGC BGC XYS BGC XYS GAL 4.51613
69 4M3P HCS 4.51613
70 5X7Q GLC GLC GLC GLC GLC 4.51613
71 5X7Q GLC GLC GLC GLC 4.51613
72 4KYS VIB 4.51613
73 4CJN QNZ 4.51613
74 5DZT AMP 4.51613
75 2FUE M1P 4.51613
76 2OVW CBI 4.51613
77 4A69 I0P 4.51613
78 4TV1 36M 5.16129
79 5XEG AKG 5.16129
80 1I9Z 2IP 5.16129
81 2QZO KN1 5.16129
82 5HYR EST 5.16129
83 3UUD EST 5.16129
84 3UU7 2OH 5.16129
85 4MGB XDH 5.16129
86 4MG8 27J 5.16129
87 5O9W AKG 5.16129
88 2R5A MLZ 5.16129
89 4TUZ 36J 5.16129
90 4MG7 27H 5.16129
91 4MGD 27N 5.16129
92 1OGX EQU 5.34351
93 5K21 6QF 5.67376
94 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 5.80645
95 4IAW LIZ 5.80645
96 3PB9 1BN 5.80645
97 1XIM XYL 5.80645
98 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 5.80645
99 4WOE ADP 5.80645
100 6F5U CQN 5.80645
101 5GNX BGC 5.80645
102 1GQG DCD 5.80645
103 1ZB6 GST 5.80645
104 4UDG NDG 5.80645
105 5MN0 A8S 6.45161
106 5MOB A8S 6.45161
107 4C91 REL 6.45161
108 2HZQ STR 6.45161
109 5I0U DCY 6.45161
110 2VFT SOR 6.45161
111 3SI2 PBD 6.45161
112 1GT4 UNA 6.45161
113 4XJ6 GH3 7.09677
114 5ISY NAD 7.09677
115 5I8T LAC 7.09677
116 6B9T 2HE 7.09677
117 4B1L FRU 7.09677
118 2YG2 S1P 7.09677
119 3MMH SME 7.09677
120 2P7Q GG6 7.5188
121 1Y7P RIP 7.62332
122 2DIO EOD 7.74194
123 3VV1 GAL FUC 7.74194
124 4ZXA H8N 7.74194
125 2QL9 CIT 7.74194
126 3N29 NSD 7.74194
127 3FW9 SLX 7.74194
128 4FFG LBS 7.74194
129 1I82 BGC BGC 8.3871
130 3GM5 CIT 8.3871
131 4COQ SAN 8.3871
132 1J3R 6PG 8.3871
133 4KIB 56D 8.3871
134 3QP8 HL0 8.3871
135 5F1V 3VN 8.3871
136 4XCB AKG 8.3871
137 4UHL VFV 9.03226
138 4LSJ LSJ 9.03226
139 2EAE FUL 9.03226
140 5NGL NOJ BGC 9.03226
141 1M6P M6P 9.21053
142 1NSZ GLC 9.67742
143 3PQB VGP 9.67742
144 4H69 10Y 10.3093
145 5INJ 6C7 10.3226
146 2R5V HHH 10.3226
147 5U9J GER 10.3226
148 1U0A BGC BGC BGC BGC 10.3226
149 1DJX I3P 10.3226
150 4NPL AKG 10.9677
151 1KKR 2AS 10.9677
152 4H6B 10Y 11.6129
153 5AVF TAU 11.6129
154 4G7A AZM 11.6129
155 4H6B 10X 11.6129
156 1YKD CMP 11.6129
157 4X5S AZM 12.2581
158 2IF8 ADP 12.2581
159 1LFO OLA 13.2812
160 1I7M PUT 13.4328
161 3DZ6 PUT 13.4328
162 4BXF AKG 13.5484
163 5BVB DOG 13.6364
164 5W0N UPU 14.1935
165 5EO8 TFU 14.1935
166 2PSJ CEI 15.4839
167 3W9R A8S 16.129
168 4DA5 0H7 16.129
169 3THR C2F 16.7742
170 2Q4X HMH 16.7742
171 4MJ0 BGC SIA SIA GAL 16.7742
172 2F2G HMH 16.7742
173 5NCF 8T5 16.8142
174 4H2X G5A 17.4757
175 3ZO7 K6H 19.1489
176 3JRS A8S 19.7115
177 5VNF VAL THR SER VAL VAL 20
178 6B9R 2HE 20.6452
179 3KDJ A8S 20.7921
180 5I8F ML1 21.2903
181 1B4U DHB 22.3022
182 4REI 3MV 22.5166
183 4LA7 A1O 22.5806
184 3NMV PYV 22.5806
185 5JNN 6LM 22.5806
186 4OIC A8S 27.7419
187 5JO1 6LM 30.3226
188 3OJI PYV 30.3226
189 4DS8 A8S 30.3226
190 4JHG ZEA 32.9032
191 2VQ5 LDP 38.0645
192 4MA6 28E 38.7097
193 4RYV ZEA 41.2903
194 4MNS 2AX 47.7419
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