Receptor
PDB id Resolution Class Description Source Keywords
4PO2 2 Å NON-ENZYME: FOLDING CRYSTAL STRUCTURE OF THE STRESS-INDUCIBLE HUMAN HEAT SHOCK P HSP70 SUBSTRATE-BINDING DOMAIN IN COMPLEX WITH PEPTIDE SUBS HOMO SAPIENS HELICAL BUNDLE CHAPERONE SUBSTRATE BINDING
Ref.: CRYSTAL STRUCTURE OF THE STRESS-INDUCIBLE HUMAN HEA PROTEIN 70 SUBSTRATE-BINDING DOMAIN IN COMPLEX WITH SUBSTRATE. PLOS ONE V. 9 03518 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ASN ARG LEU LEU LEU THR GLY D:1;
C:1;
Valid;
Valid;
none;
none;
submit data
713.878 n/a O=C([...
SO4 A:701;
B:701;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
PO4 A:702;
Invalid;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4PO2 2 Å NON-ENZYME: FOLDING CRYSTAL STRUCTURE OF THE STRESS-INDUCIBLE HUMAN HEAT SHOCK P HSP70 SUBSTRATE-BINDING DOMAIN IN COMPLEX WITH PEPTIDE SUBS HOMO SAPIENS HELICAL BUNDLE CHAPERONE SUBSTRATE BINDING
Ref.: CRYSTAL STRUCTURE OF THE STRESS-INDUCIBLE HUMAN HEA PROTEIN 70 SUBSTRATE-BINDING DOMAIN IN COMPLEX WITH SUBSTRATE. PLOS ONE V. 9 03518 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 22 families.
1 4PO2 - ASN ARG LEU LEU LEU THR GLY n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 4PO2 - ASN ARG LEU LEU LEU THR GLY n/a n/a
50% Homology Family (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 4EZX Kd = 1.6 uM ASN ARG LEU MET LEU THR GLY n/a n/a
2 4R5I Kd ~ 10 uM ASN ARG LEU LEU LEU THR GLY n/a n/a
3 4JWI - PRO ARG PRO ILE LEU LEU PRO TRP ARG NH2 n/a n/a
4 4EZQ Kd = 6.3 uM PRO PRO ARG PRO ILE TYR ASN ARG ASN n/a n/a
5 4EZR Kd = 6.3 uM SER HIS PRO ARG PRO ILE ARG VAL n/a n/a
6 4EZZ Kd = 6.4 uM GLU LEU PRO LEU VAL LYS ILE n/a n/a
7 4F00 - ASN ARG PRO VAL TYR ILE PRO PRO PRO PRO n/a n/a
8 1DKX - ASN ARG LEU LEU LEU THR GLY n/a n/a
9 4E81 - ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO n/a n/a
10 1DKZ - ASN ARG LEU LEU LEU THR GLY n/a n/a
11 4EZT Kd = 7.4 uM PRO ARG ARG PRO VAL ILE MET ARG ARG n/a n/a
12 4EZW Kd = 1 uM ASN ARG LEU LEU LEU THR GLY n/a n/a
13 4EZY Kd = 2.26 uM ASN ARG LEU ILE LEU THR GLY n/a n/a
14 1U00 - GLU LEU PRO PRO VAL LYS ILE HIS CYS n/a n/a
15 4PO2 - ASN ARG LEU LEU LEU THR GLY n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ASN ARG LEU LEU LEU THR GLY; Similar ligands found: 50
No: Ligand ECFP6 Tc MDL keys Tc
1 ASN ARG LEU LEU LEU THR GLY 1 1
2 ASN ARG LEU MET LEU THR GLY 0.67033 0.877193
3 ALA ALA LEU THR ARG ALA 0.526882 0.941176
4 ARG LEU GLN ARG ARG ARG GLU THR GLN VAL 0.490196 0.943396
5 THR ARG ARG GLU THR GLN LEU 0.474747 0.943396
6 ASP LEU THR ARG PRO 0.466667 0.769231
7 ALA PRO ALA LEU ARG VAL VAL LYS 0.452632 0.830189
8 GLU ALA GLN THR ARG LEU 0.451923 0.980392
9 ALA ARG LYS LEU ASP 0.450549 0.867925
10 MET ABA LEU ARG MET THR ALA VAL MET 0.45045 0.859649
11 ALA ARG THR GLU LEU TYR ARG SER LEU 0.444444 0.833333
12 PHE ARG TYR LEU GLY 0.444444 0.783333
13 ALA ARG THR MLY GLN 0.444444 0.864407
14 ALA ARG MLY SER THR GLY GLY ALY 0.443478 0.822581
15 PHE ALA GLY LEU ARG GLN ALA VAL THR GLN 0.439252 0.961538
16 VAL ARG SER ARG ARG CYS LEU ARG LEU 0.438776 0.872727
17 MET CYS LEU ARG MET THR ALA VAL MET 0.438596 0.859649
18 ALA ARG THR MLY GLN THR ALA ARG LYS SER 0.4375 0.903846
19 MET CYS LEU ARG NLE THR ALA VAL MET 0.435897 0.844828
20 ALA ARG MLZ SER THR GLY GLY ALY 0.434783 0.847458
21 VAL LEU ARG ASP ASP LEU LEU GLU ALA 0.434343 0.867925
22 ALA ARG M3L SER THR GLY GLY ALY 0.431034 0.796875
23 VAL ARG SER ARG ARG ABA LEU ARG LEU 0.43 0.872727
24 ARG ARG ARG TRP ARG ARG LEU THR VAL 0.42735 0.765625
25 ASN ARG LEU ILE LEU THR GLY 0.425743 0.830189
26 ALA ARG THR ALY GLN THR ALA 0.423077 0.872727
27 ALA ARG THR MLY GLN THR ALA ARG MLY SER 0.421569 0.847458
28 THR ILE MET MET GLN ARG GLY 0.420561 0.844828
29 LEU TYR LEU VAL CYS GLY GLU ARG GLY 0.419355 0.813559
30 SAC ARG GLY THR GLN THR GLU 0.418182 0.907407
31 ALA ARG LYS SEP THR GLY GLY LYS 0.417391 0.746032
32 LYS ALA ARG VAL LEU ALA GLU ALA MET SER 0.415929 0.818182
33 ALA GLN THR ALA ARG ALY SER THR 0.415929 0.857143
34 LYS ALA ARG VAL LEU ALA GLU ALA MET 0.415929 0.818182
35 ALA ARG THR 4WQ GLN THR ALA ARG LYS SER 0.414141 0.875
36 SER ARG LYS ILE ASP ASN LEU ASP 0.413793 0.844828
37 LYS PRO VAL LEU ARG THR ALA 0.411765 0.753846
38 ARG ARG LEU ILE PHE NH2 0.411215 0.75
39 ALA ARG THR LYS GLN THR ALA ARG LYS SER 0.411215 0.87037
40 ALA MET ALA PRO ARG THR LEU LEU LEU 0.409836 0.724638
41 LYS GLN THR ALA ARG M3L SER THR GLY 0.409091 0.793651
42 LEU LYS THR LYS LEU LEU 0.408602 0.773585
43 ALA ARG LYS ILE ASP ASN LEU ASP 0.40708 0.824561
44 ALA ARG THR MLY GLN THR ALA 0.40566 0.833333
45 ALA ARG THR MLY GLN THR ALA ARG LYS TYR 0.40566 0.833333
46 SER GLU LEU GLU ILE LYS ARG TYR 0.404959 0.819672
47 ACE ALA ARG THR LYS GLN 0.40404 0.867925
48 LYS THR LYS LEU LEU 0.402174 0.773585
49 THR ALA ARG M3L SER THR GLY GLY LYS ALA 0.401639 0.793651
50 ALA ARG THR M3L GLN THR ALA ARG 0.4 0.822581
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4PO2; Ligand: ASN ARG LEU LEU LEU THR GLY; Similar sites found: 467
This union binding pocket(no: 1) in the query (biounit: 4po2.bio3) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1SS4 CIT 0.0003132 0.58693 None
2 1PTR PRB 0.0005319 0.48243 None
3 1SS4 GSH 0.00476 0.4786 None
4 2ALG DAO 0.0005711 0.46566 None
5 1UO5 PIH 0.006211 0.46484 None
6 3QDW NDG 0.002319 0.4525 None
7 3QDW A2G 0.006348 0.44635 None
8 3QDV NDG 0.003488 0.4442 None
9 3QDV A2G 0.01093 0.43435 None
10 3QDT A2G GAL 0.008171 0.43347 None
11 1UO4 PIH 0.01832 0.43026 None
12 1NU4 MLA 0.02103 0.42706 None
13 3QDY CBS 0.0106 0.42155 None
14 2BOI MFU 0.004962 0.41929 None
15 2FR6 CTN 0.001146 0.4113 None
16 2FR6 URI 0.001622 0.40613 None
17 3QDY A2G GAL 0.03192 0.40444 None
18 3UST FAD 0.003797 0.40104 0.374532
19 4B9E FAH 0.0195 0.40907 0.851064
20 4P9Z NMI PTR 02K ASN NH2 0.001342 0.44323 0.854701
21 1Y9Q MED 0.003588 0.43699 1.04167
22 1Z42 HBA 0.0002483 0.54582 1.2766
23 1Z44 NPO 0.0009247 0.51082 1.2766
24 2QV7 ADP 0.00006547 0.46491 1.2766
25 4BI7 PGA 0.001928 0.43098 1.2766
26 4LIT AKG 0.00385 0.42954 1.2766
27 1TRD PGH 0.001369 0.42648 1.2766
28 1Z42 FMN 0.003183 0.41241 1.2766
29 2OWZ CIT 0.01309 0.41154 1.2766
30 1Z48 FMN 0.003434 0.40262 1.2766
31 4EXO PYR 0.0008333 0.48175 1.36986
32 3EW2 BTN 0.0001386 0.47761 1.48148
33 2V5E SCR 0.0004851 0.51395 1.5
34 1ZZ7 S0H 0.0007496 0.45389 1.51515
35 3SCH TB6 0.005588 0.42829 1.51515
36 1ZJ6 G3D 0.003652 0.41012 1.60428
37 3S9K CIT 0.004689 0.48237 1.69492
38 2ZE3 AKG 0.0003147 0.47693 1.70213
39 2WGC SIA GAL BGC 0.02498 0.43105 1.75439
40 1WGC SIA GAL BGC 0.02234 0.42565 1.75439
41 2JBH 5GP 0.002658 0.42529 1.77778
42 1N9L FMN 0.000603 0.42086 1.83486
43 4K30 NLG 0.005107 0.41876 1.875
44 4TMK T5A 0.01674 0.41654 1.87793
45 3UDG TMP 0.0005168 0.50159 2.12766
46 1Y7I SAL 0.0001773 0.48026 2.12766
47 2QCX PF1 0.0004869 0.46868 2.12766
48 1KTC NGA 0.0007585 0.45367 2.12766
49 1T3D CYS 0.003405 0.44469 2.12766
50 1WDA BAG 0.001446 0.43608 2.12766
51 3CEV ARG 0.002843 0.42409 2.12766
52 2NVK NAP 0.004068 0.42293 2.12766
53 1UAY ADN 0.002026 0.41532 2.12766
54 3NFZ 3NF 0.002776 0.4147 2.12766
55 4N02 FNR 0.005272 0.41036 2.12766
56 1XX4 BAM 0.01334 0.4035 2.12766
57 2V7T SAH 0.02823 0.40051 2.12766
58 2IUW AKG 0.01085 0.4003 2.12766
59 2XI7 XI7 0.00001187 0.61585 2.17391
60 3E6J DR2 0.03234 0.41353 2.18341
61 2Q37 3AL 0.0006172 0.46419 2.20994
62 3I6B KDO 0.0001089 0.48918 2.22222
63 1OGD RIP 0.004692 0.42031 2.29008
64 3CH5 GDP 0.003115 0.41278 2.31481
65 3NNF AKG 0.002475 0.44427 2.32558
66 4A6F SEP 0.003202 0.47053 2.5
67 1E2S CSN 0.0001953 0.45317 2.55319
68 2DVZ GLU 0.0004743 0.4498 2.55319
69 2XDQ MGX 0.006257 0.44666 2.55319
70 1ZUW DGL 0.001019 0.44227 2.55319
71 4WVH ASP HIS ASP ALA HIS ALA 0.001104 0.44085 2.55319
72 4QVH FLC 0.02307 0.43441 2.55319
73 4CIB 7UZ 0.003586 0.43089 2.55319
74 1NML CIT 0.002652 0.43076 2.55319
75 3U1T MLI 0.007345 0.42903 2.55319
76 1P72 THM 0.00313 0.42773 2.55319
77 3I8P 840 0.00076 0.42636 2.55319
78 4KSY 1SY 0.002583 0.4258 2.55319
79 1V7R CIT 0.02478 0.42324 2.55319
80 3O2K QRP 0.002358 0.42226 2.55319
81 2OI2 DP6 0.001796 0.42196 2.55319
82 2YVF NAD 0.003885 0.42111 2.55319
83 2YVF FAD 0.00372 0.42111 2.55319
84 2Y7G AAE 0.001112 0.42037 2.55319
85 1MZV AMP 0.003093 0.41759 2.55319
86 2QF7 COA 0.002081 0.41488 2.55319
87 1A5V Y3 0.009445 0.41252 2.55319
88 1YHM AHD 0.009826 0.41177 2.55319
89 3N5O GSH 0.001225 0.41031 2.55319
90 4BT5 23B 0.007636 0.40655 2.55319
91 1QB7 ADE 0.006161 0.40574 2.55319
92 4AMV F6R 0.003073 0.40437 2.55319
93 1E5F PLP 0.003077 0.40435 2.55319
94 4JEJ 1GP 0.005695 0.40271 2.55319
95 1II5 GLU 0.001758 0.44439 2.57511
96 1QH9 LAC 0.001518 0.45386 2.58621
97 3KYF 5GP 5GP 0.00286 0.41894 2.5974
98 2X0K PPV 0.006822 0.41602 2.66272
99 1GU3 BGC BGC BGC BGC BGC 0.002527 0.43165 2.68456
100 2HVW DDN 0.001272 0.42285 2.71739
101 2Y7P SAL 0.002762 0.43002 2.75229
102 3BY8 MLT 0.004003 0.4414 2.8169
103 2BO4 FLC 0.002171 0.45384 2.97872
104 2B7N NTM 0.001658 0.4455 2.97872
105 4HZO COA 0.001314 0.44362 2.97872
106 2VQ5 LDP 0.008825 0.43907 2.97872
107 3PLN U5P 0.002047 0.4355 2.97872
108 1GVF PGH 0.002476 0.43202 2.97872
109 1VBH PEP 0.004404 0.427 2.97872
110 1Z45 GAL 0.004459 0.42124 2.97872
111 3Q9T FAY 0.001325 0.41933 2.97872
112 1NHZ 486 0.0002939 0.41856 2.97872
113 2R00 OEG 0.01497 0.41449 2.97872
114 2VQ5 HBA 0.01893 0.40968 2.97872
115 3V1U HXC 0.006001 0.40619 2.97872
116 4C6F DOR 0.006274 0.40543 2.97872
117 4C6F NCD 0.006274 0.40543 2.97872
118 1WUR 8DG 0.000805 0.4047 2.97872
119 3PNL ADP 0.0009451 0.40249 2.97872
120 1JAC AMG 0.001854 0.48311 3.00752
121 2PR5 FMN 0.00006117 0.45492 3.0303
122 1VQ2 DDN 0.001207 0.41469 3.10881
123 1Y7P RIP 0.009562 0.43013 3.13901
124 3GD8 BOG 0.01435 0.42151 3.13901
125 1R37 NAD 0.00242 0.40567 3.17003
126 4BCS BTN 0.002282 0.40906 3.2
127 1NXJ TLA 0.001643 0.41207 3.27869
128 1NXJ GLV 0.007409 0.40709 3.27869
129 2YD6 FLC 0.0004673 0.54358 3.30189
130 2GJ3 FAD 0.000577 0.40928 3.33333
131 3BHO B4P 0.007209 0.45183 3.36538
132 3ZPG 5GP 0.001918 0.47272 3.40314
133 1RYI GOA 0.002595 0.48643 3.40426
134 2VDJ HSE 0.000784 0.48303 3.40426
135 1GJW GLC 0.0006168 0.47942 3.40426
136 1DXY COI 0.001703 0.47534 3.40426
137 3K3G MMU 0.0003451 0.47156 3.40426
138 2HFK E4H 0.0005265 0.46035 3.40426
139 3CL5 SIO 0.001706 0.45875 3.40426
140 1O68 KIV 0.0008033 0.45262 3.40426
141 3SHR CMP 0.0009664 0.43758 3.40426
142 4M2K PLP 0.001467 0.43582 3.40426
143 1FBL HTA 0.001094 0.43546 3.40426
144 3GJB AKG 0.001657 0.43366 3.40426
145 1GJW MAL 0.001302 0.43246 3.40426
146 4CCO OGA 0.004645 0.42049 3.40426
147 1V5F TPP 0.0223 0.4199 3.40426
148 1V5F FAD 0.0223 0.4199 3.40426
149 4JLV ADP 0.03828 0.41672 3.40426
150 2RCN GDP 0.0037 0.41451 3.40426
151 2YFT DQR 0.001891 0.41202 3.40426
152 3CF6 SP1 0.001921 0.41177 3.40426
153 2OKK ABU 0.02334 0.41114 3.40426
154 3FXU TSU 0.0002646 0.40957 3.40426
155 1B5E DCM 0.006843 0.4085 3.40426
156 3P0F BAU 0.003741 0.40128 3.40426
157 1Q3Q ANP 0.0107 0.40068 3.40426
158 2WQP WQP 0.00182 0.40017 3.40426
159 3CBG FER 0.004323 0.45482 3.44828
160 3CBG 4FE 0.01063 0.44288 3.44828
161 3CBG SAH 0.001111 0.41596 3.44828
162 6FIV 3TL 0.002871 0.40967 3.53982
163 1JGS SAL 0.0008295 0.51344 3.62319
164 1C1L GAL BGC 0.004964 0.43701 3.64964
165 3E81 SLB 0.01162 0.40858 3.65854
166 2O66 FLC 0.004103 0.42834 3.7037
167 1YOE RIB 0.001634 0.43391 3.72671
168 3L6R MLI 0.0006149 0.47948 3.75723
169 1BTN I3P 0.0002533 0.54757 3.77358
170 3F81 STT 0.007246 0.44343 3.82514
171 4B16 NAG 0.0002205 0.53208 3.82979
172 3I7S PYR 0.0001936 0.51257 3.82979
173 3ZGE ASP 0.0005126 0.49201 3.82979
174 2Q8H TF4 0.0008055 0.49182 3.82979
175 3VPD BUA 0.003343 0.48655 3.82979
176 2ZJ5 ADP 0.0004523 0.47007 3.82979
177 3BK2 U5P 0.0001436 0.46406 3.82979
178 3VPD CIT 0.005391 0.45853 3.82979
179 1O9U ADZ 0.005652 0.44891 3.82979
180 4ME6 ADP 0.001731 0.44468 3.82979
181 2W8Q SIN 0.005511 0.43489 3.82979
182 3MAG 3MA 0.01509 0.43476 3.82979
183 4F2Q QUS 0.001568 0.41947 3.82979
184 2JC9 ADN 0.004982 0.41921 3.82979
185 3P3N AKG 0.01087 0.41522 3.82979
186 1T8U A3P 0.0007248 0.41395 3.82979
187 2Q1A 2KT 0.01318 0.41141 3.82979
188 2FOI JPA 0.004823 0.40995 3.82979
189 2XUM OGA 0.01465 0.40933 3.82979
190 3MCT 3MC 0.009769 0.40685 3.82979
191 1KYQ NAD 0.001963 0.40329 3.82979
192 1C3V PDC 0.01703 0.4013 3.82979
193 4Q0A 4OA 0.002345 0.40064 3.82979
194 3PNA CMP 0.0009925 0.44274 3.8961
195 2BZ1 TAU 0.04007 0.41947 4.08163
196 2WMO GTP 0.003554 0.40621 4.20561
197 3DDC GNP 0.0001858 0.40929 4.21687
198 2HGS GSH 0.00008526 0.46658 4.25532
199 4C2G ALA ALA ALA ALA 0.0003161 0.46301 4.25532
200 1AX2 NDG GAL 0.0005997 0.45797 4.25532
201 1I1Q TRP 0.0005243 0.45405 4.25532
202 3W54 RNB 0.0002569 0.44873 4.25532
203 1WTC ACP 0.006036 0.43303 4.25532
204 1PX8 XYP 0.003703 0.43028 4.25532
205 4N7U 2JA 0.0164 0.42536 4.25532
206 3JDW ORN 0.0008656 0.42431 4.25532
207 4B4D FAD 0.0002771 0.42354 4.25532
208 2ZJF BSU 0.003496 0.41549 4.25532
209 2OHV NHL 0.004696 0.41519 4.25532
210 4KCF FMN 0.002581 0.40712 4.25532
211 2BII MTV 0.0005399 0.40541 4.25532
212 1ZGA SAH 0.004778 0.40142 4.25532
213 2WCV FUC 0.001199 0.4394 4.28571
214 3WUC GLC GAL 0.01084 0.41527 4.37956
215 1NPL MAN 0.02221 0.4011 4.58716
216 3O03 GCO 0.001337 0.48067 4.68085
217 1CKN GTP 0.0001779 0.47319 4.68085
218 1Y42 TYR 0.0002979 0.47077 4.68085
219 1CKM GTP 0.0004277 0.45765 4.68085
220 3L24 GOA 0.005013 0.45156 4.68085
221 1VR0 3SL 0.0008247 0.44603 4.68085
222 1WRA PC 0.003994 0.44144 4.68085
223 1SQ5 PAU 0.002634 0.43089 4.68085
224 4JWX 1N4 0.002687 0.43053 4.68085
225 1YBH P22 0.002058 0.42459 4.68085
226 1TV5 N8E 0.0004925 0.42388 4.68085
227 1SQ5 ADP 0.002283 0.41796 4.68085
228 1ZED PNP 0.01268 0.41789 4.68085
229 3K56 IS3 0.002351 0.41291 4.68085
230 1YRO UDP 0.04209 0.40897 4.68085
231 2HGZ PBF 0.0003049 0.40724 4.68085
232 3VCA PRO 0.0111 0.40693 4.68085
233 4F8L GAL 0.005322 0.46857 4.82759
234 1YRX FMN 0.001877 0.41655 4.95868
235 1UW1 ADP 0.0008421 0.45832 5
236 3JQM GTP 0.009134 0.40337 5.09554
237 3UBW 6SP 0.00006345 0.58851 5.10638
238 4WBD ADP 0.0005245 0.48272 5.10638
239 4W6Z ETF 0.0034 0.46011 5.10638
240 3QV9 QV7 0.0009905 0.45524 5.10638
241 4KCT FDP 0.0002697 0.45355 5.10638
242 4O8A 2OP 0.004649 0.45322 5.10638
243 1RZM E4P 0.004432 0.43932 5.10638
244 4KOA NDP 0.00036 0.4332 5.10638
245 3I0O SMI 0.005138 0.42408 5.10638
246 4JP3 CIT 0.001745 0.42244 5.10638
247 2PTZ PAH 0.00005699 0.42244 5.10638
248 3I0O ADP 0.002498 0.42127 5.10638
249 4KCT PYR 0.003411 0.42086 5.10638
250 3JQ3 ADP 0.004085 0.41281 5.10638
251 3MD0 GDP 0.005472 0.41247 5.10638
252 4WBD CIT 0.02281 0.41163 5.10638
253 2FGQ MLT 0.0156 0.40809 5.10638
254 1RZM PEP 0.0105 0.40553 5.10638
255 3I51 45C 0.005629 0.4029 5.10638
256 1KYZ SAH 0.002386 0.40038 5.10638
257 4Q3F TLA 0.0007863 0.46674 5.12821
258 1QY1 PRZ 0.001188 0.40298 5.17241
259 2F2U M77 0.003259 0.4167 5.22388
260 3R6K FUC GAL GLA 0.01285 0.41762 5.2459
261 1TUV VK3 0.002097 0.47076 5.26316
262 1JH7 UVC 0.001213 0.45141 5.29101
263 4K7O EKZ 0.01766 0.41111 5.35714
264 4JCA CIT 0.006383 0.45464 5.38922
265 1XE7 GUN 0.001196 0.48313 5.41872
266 3UEC ALA ARG TPO LYS 0.005202 0.43606 5.47945
267 1V6A TRE 0.0009448 0.45614 5.53191
268 4M51 BEZ 0.005664 0.44123 5.53191
269 1Q11 TYE 0.002727 0.43025 5.53191
270 1LYX PGA 0.002647 0.41099 5.53191
271 1AUA BOG 0.009815 0.40677 5.53191
272 3ZUY TCH 0.007201 0.40305 5.53191
273 4L1F COS 0.0006454 0.40267 5.53191
274 3A2Y TS5 0.002907 0.40124 5.58376
275 1XIU REA 0.0003831 0.43225 5.65217
276 3GM5 CIT 0.001314 0.45668 5.66038
277 3DCM SAM 0.001258 0.40596 5.72917
278 2F59 INI 0.0007078 0.41847 5.73248
279 4R3L COA 0.000703 0.42525 5.78035
280 4COQ SAN 0.00021 0.4926 5.95745
281 4UAL 3FV 0.0005357 0.42712 5.95745
282 1UBY DMA 0.0009713 0.41802 5.95745
283 2NCD ADP 0.008517 0.41449 5.95745
284 2C5S AMP 0.005476 0.41246 5.95745
285 3TXO 07U 0.003793 0.40516 5.95745
286 1POC GEL 0.0008385 0.42027 5.97015
287 3KJQ B94 0.002779 0.41468 6.09756
288 2UZ2 BTN 0.001619 0.41446 6.15385
289 3H86 AP5 0.003696 0.41634 6.25
290 1M1B SPV 0.001861 0.44331 6.38298
291 3P7I P7I 0.001478 0.44146 6.38298
292 2ZYF AKG 0.001855 0.43167 6.38298
293 4LHM AZZ 0.004344 0.42726 6.38298
294 3SIX GDP 0.003112 0.41279 6.38298
295 1UF5 CDT 0.004399 0.41154 6.38298
296 1CBF SAH 0.001972 0.41136 6.38298
297 3LST SAH 0.003817 0.40938 6.38298
298 4DYO SD4 0.007338 0.40726 6.38298
299 1PR9 NAP 0.002348 0.40487 6.38298
300 1H8P PC 0.0007206 0.49428 6.42202
301 2IYG FMN 0.0009453 0.43266 6.45161
302 1QR0 COA 0.003893 0.41364 6.57895
303 3WUD GLC GAL 0.009849 0.42951 6.61765
304 4FGC PQ0 0.0007066 0.46163 6.66667
305 3NCQ ATP 0.0003237 0.42134 6.72269
306 2VPR TDC 0.003251 0.40349 6.76329
307 1P9B HDA 0.001484 0.4476 6.78733
308 1B74 DGN 0.0001197 0.52273 6.80851
309 1HQL GLA MBG 0.0005704 0.48101 6.80851
310 1PEA ACM 0.002112 0.4621 6.80851
311 1R6W 164 0.0007511 0.42654 6.80851
312 1T10 F6P 0.004671 0.42588 6.80851
313 1A59 CIT 0.01215 0.41876 6.80851
314 3PJU C2E 0.000821 0.41143 6.80851
315 1SC3 MLI 0.003244 0.45303 6.81818
316 4AF5 CIT 0.009417 0.41803 6.84211
317 1TH8 ADP 0.00593 0.4064 6.89655
318 4DN8 BMA 0.004098 0.43438 7.05128
319 4NPT 017 0.007188 0.40308 7.07071
320 1HFA PIO 0.0007319 0.54245 7.23404
321 3SQG COM 0.003672 0.46738 7.23404
322 2Q3M MLA 0.004721 0.45288 7.23404
323 2JFV FLC 0.004435 0.43283 7.23404
324 3CQ5 PMP 0.002278 0.42802 7.23404
325 4KGM ATP 0.002 0.42016 7.23404
326 1QDS PGA 0.00407 0.41287 7.23404
327 4USS GSH 0.0096 0.40717 7.23404
328 3A1I UNU 0.005883 0.40653 7.23404
329 2FYU FDN 0.001083 0.41214 7.27273
330 2AZ3 CDP 0.002603 0.4311 7.31707
331 1ECM TSA 0.002256 0.42819 7.33945
332 4INB 1F6 0.0014 0.4044 7.53425
333 2W3L DRO 0.03681 0.40734 7.63889
334 3IHB TRS 0.0006194 0.52549 7.65957
335 3IHB GLU 0.000462 0.48529 7.65957
336 1X8X TYR 0.00009097 0.47815 7.65957
337 2YIV NBN 0.001715 0.45863 7.65957
338 3TFC PEP 0.002254 0.43374 7.65957
339 1OIK AKG 0.01105 0.41489 7.65957
340 2WE5 ADP 0.002631 0.41108 7.65957
341 2YIV YIV 0.03292 0.40378 7.65957
342 1FIQ MTE 0.00236 0.40085 7.65957
343 1FIQ SAL 0.002836 0.40085 7.65957
344 2ZSC BTN 0.0002045 0.45243 7.80142
345 4F4S EFO 0.0031 0.42791 7.89474
346 1UJ5 5RP 0.00422 0.40771 7.92952
347 2XRH NIO 0.00009359 0.51773 8
348 2E1A MSE 0.000127 0.47916 8
349 1GPJ CIT 0.00001924 0.53941 8.08511
350 3HZL 6PC 0.003713 0.45818 8.08511
351 1KC7 PPR 0.008648 0.4257 8.08511
352 4GYW UDP 0.001093 0.41474 8.08511
353 3PMA SCR 0.008281 0.40989 8.08511
354 4OB6 S2T 0.0002599 0.44323 8.21114
355 1NF8 BOG 0.002417 0.45166 8.21256
356 1NF8 ISC 0.002371 0.41733 8.21256
357 1Q3P GLU ALA GLN THR ARG LEU 0.0004985 0.43299 8.25688
358 2YCD GTB 0.001336 0.4269 8.26087
359 2D0V PQQ 0.00115 0.40726 8.33333
360 2QLX RM4 0.02547 0.40359 8.33333
361 4LO6 SIA GAL 0.00008095 0.52571 8.42105
362 2X2T GAL NGA 0.001421 0.47933 8.49673
363 3TKA CTN 0.001345 0.48527 8.51064
364 2P69 PLP 0.0003462 0.47513 8.51064
365 3TKA SAM 0.0008546 0.40763 8.51064
366 2H6T IVA VAL VAL STA ALA STA 0.003134 0.40009 8.51064
367 1UCN ADP 0.004599 0.40203 8.55263
368 4CCN OGA 0.004237 0.43372 8.57143
369 3BRE C2E 0.00126 0.45751 8.65922
370 1G8S MET 0.001437 0.45493 8.69565
371 1Q6O LG6 0.0006461 0.42891 8.7963
372 3WCS MAN NAG GAL 0.0005634 0.44685 8.93617
373 3WCS MAN NAG 0.002237 0.43388 8.93617
374 2PUL ACP 0.0006549 0.4287 8.93617
375 2IZ1 ATR 0.005948 0.42706 8.93617
376 2BH9 NAP 0.001739 0.41334 8.93617
377 3IB9 BTN 0.01832 0.41326 8.93617
378 2DTJ THR 0.006045 0.40607 8.98876
379 1WHT BZS 0.001393 0.45554 9.15033
380 1ULE GLA GAL NAG 0.0115 0.42622 9.33333
381 2QGI UDP 0.01416 0.40482 9.3617
382 1UOU CMU 0.004502 0.40238 9.3617
383 1F1V DHY 0.01073 0.4005 9.3617
384 1T0I FMN 0.001455 0.40775 9.42408
385 3GF2 SAL 0.03188 0.40447 9.58904
386 1L1Q 9DA 0.0002869 0.42738 9.67742
387 1QO0 BMD 0.004329 0.4333 9.69388
388 1RYD GLC 0.004596 0.43213 9.78723
389 1SOW OXL 0.01708 0.42446 9.78723
390 3DG6 MUC 0.001418 0.42109 9.78723
391 1EYQ NAR 0.0008786 0.4449 9.90991
392 5FIT AP2 0.001119 0.42984 10.2041
393 3LTW HLZ 0.0007388 0.46796 10.2128
394 4RJK PYR 0.006394 0.43866 10.2128
395 4NAO AKG 0.005681 0.43427 10.2128
396 1I0Z OXM 0.01272 0.43099 10.2128
397 3T1A 5MA 0.0008892 0.41508 10.2128
398 1PFK ADP 0.00167 0.41397 10.2128
399 1IYE PGU 0.002622 0.40068 10.2128
400 3RF4 FUN 0.001945 0.43644 10.3448
401 2OFD NGA 0.0003008 0.48556 10.5634
402 2OFE NAG 0.001311 0.45673 10.5634
403 2YP9 SIA CMO 0.0002367 0.44213 10.6383
404 3K5X P8D 0.001462 0.43047 10.6383
405 4DQ2 BTX 0.0003639 0.42622 10.6383
406 2D5X L35 0.008517 0.41449 10.6383
407 5D63 FUC GLA GLA 0.02055 0.40264 10.6383
408 4JHG ZEA 0.002846 0.40558 10.7143
409 4WX0 HXD 0.001597 0.41468 11.0266
410 1T0S BML 0.001653 0.46727 11.0638
411 3GTD MLI 0.002224 0.43994 11.0638
412 1Y13 BIO 0.005011 0.4093 11.0638
413 2WCI GSH 0.01204 0.40791 11.1111
414 3R51 MMA 0.0005971 0.49841 11.25
415 4N7C AEF 0.001195 0.46597 11.3636
416 2HW1 FRU 0.001261 0.45068 11.4894
417 1FMB HYB 0.005536 0.40318 11.5385
418 4G4S LDZ 0.0000727 0.45767 11.811
419 1H16 PYR 0.0004916 0.49289 11.9149
420 9LDT OXM 0.01051 0.44313 11.9149
421 9LDB OXM 0.026 0.42212 11.9149
422 4E28 9MZ 0.01086 0.41522 11.9149
423 3ZF8 GDP 0.003692 0.41455 11.9149
424 3RKR NAP 0.004951 0.4095 11.9149
425 1H16 DTL 0.03599 0.40784 11.9149
426 4E28 0MZ 0.01579 0.40274 11.9149
427 4EPL JAI 0.004017 0.40015 11.9149
428 4NC7 I3C 0.01032 0.42209 12.1212
429 1EB9 HBA 0.003148 0.4126 12.3404
430 3NKS ACJ 0.003145 0.40401 12.3404
431 1ZS6 ADP 0.008812 0.40401 12.426
432 2YLD CMO 0.009772 0.4173 12.5984
433 1JN2 SFP 0.009987 0.47674 12.6582
434 3W8S GSH 0.01169 0.40846 12.766
435 1Y1A GSH 0.02418 0.43521 13.1148
436 1YFZ IMP 0.001332 0.44964 13.1707
437 2EB5 OXL 0.0002808 0.48691 13.1915
438 3NOJ PYR 0.00634 0.41739 13.4454
439 4LKK SIA GAL 0.00178 0.40474 13.6905
440 4HA6 PXM 0.0005807 0.46534 14.0426
441 2ZWS PLM 0.003116 0.4815 14.4681
442 2DWU DGL 0.001376 0.43695 14.4681
443 1H8G CHT 0.0004601 0.52766 14.7368
444 4U9W SER GLY ARG GLY LYS NH2 0.005719 0.42488 14.8936
445 4U9W COA 0.001381 0.40654 14.8936
446 1VE3 SAM 0.0003104 0.43074 14.978
447 1FW1 GSH 0.000751 0.43138 15.2778
448 4M5P MLA 0.003991 0.46546 15.3191
449 4M5P 23W 0.004111 0.44801 15.3191
450 1Y2W NAG 0.001817 0.45033 15.493
451 3O7B SAH 0.0005615 0.42192 15.5738
452 5RHN 8BR 0.002527 0.40745 15.6522
453 2NZU BG6 0.007016 0.41293 15.9091
454 4G28 0W8 0.001936 0.43091 16.1074
455 1H2M OGA 0.01312 0.41151 17.3077
456 1FWE HAE 0.009136 0.40336 17.8723
457 2OYS FMN 0.0005989 0.41265 18.1818
458 1QD0 RR6 0.003343 0.4116 18.75
459 1NME 159 0.003072 0.40858 19.1781
460 1YOA FMN 0.01312 0.44672 20.1258
461 2VAR KDG 0.00009979 0.47011 23.4043
462 2VAR AMP 0.0004086 0.45236 23.4043
463 2VAR KDF 0.0008275 0.43487 23.4043
464 1Y75 NAG 0.005696 0.41176 23.7288
465 1U3I GSH 0.01583 0.4027 28.91
466 3EYK EYK 0.01463 0.40935 31.3953
467 2P8O BVA 0.00164 0.41 46.1538
Pocket No.: 2; Query (leader) PDB : 4PO2; Ligand: ASN ARG LEU LEU LEU THR GLY; Similar sites found: 74
This union binding pocket(no: 2) in the query (biounit: 4po2.bio3) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1MQ0 BRD 0.001846 0.4203 None
2 3SJ0 DXC 0.027 0.40532 None
3 1Z44 FMN 0.0005888 0.43902 1.2766
4 2Q8M AMP 0.007516 0.40126 1.2766
5 2IMP LAC 0.001672 0.40532 1.70213
6 1QZZ SAM 0.001725 0.42141 2.12766
7 2Q09 DI6 0.005144 0.41684 2.12766
8 2Z9V PXM 0.0008746 0.45469 2.55319
9 2R42 FPS 0.0009369 0.41384 2.55319
10 5T0A A3P 0.004495 0.41217 2.55319
11 1MOQ GLP 0.002545 0.40283 2.55319
12 2YDW WSH 0.009445 0.40152 2.61438
13 1U5R ATP 0.001771 0.41654 2.97872
14 4LSJ LSJ 0.0003536 0.40286 2.97872
15 2JGS BTN 0.01019 0.41167 3.07692
16 1V2G OCA 0.004966 0.40827 3.15789
17 1W3R PYR 0.00704 0.43983 3.24074
18 2GWD GLU 0.003016 0.42642 3.40426
19 1EYE PMM 0.002473 0.42005 3.40426
20 4J7H TLO 0.002953 0.40058 3.40426
21 1F5F DHT 0.0009129 0.42259 3.41463
22 1B55 4IP 0.0009171 0.43176 3.5503
23 4B7E OGA 0.00009228 0.50421 3.82979
24 2WA4 069 0.000822 0.43862 3.82979
25 2Y0I AKG 0.01211 0.4109 3.82979
26 2HEK GDP 0.00857 0.40322 3.82979
27 2PYU IMP 0.01925 0.40197 4.10959
28 4L7I SAM 0.0004676 0.43296 4.25532
29 1ZGA HMK 0.002718 0.41845 4.25532
30 1H0C AOA 0.01705 0.41486 4.25532
31 4IHQ ADP 0.00647 0.41272 4.25532
32 4OYA 1VE 0.01663 0.40797 4.25532
33 3K3K A8S 0.001733 0.4048 4.2654
34 2Y6P CTP 0.0007622 0.44531 4.2735
35 1NPL MAN MAN 0.02682 0.41111 4.58716
36 1AUX AGS 0.0008119 0.4244 4.68085
37 1GSA GSH 0.001746 0.40852 4.68085
38 1WVG CXY 0.0008272 0.40796 4.68085
39 1OGZ EQU 0.001033 0.43477 4.8
40 2PFC PLM 0.0001037 0.47352 4.91803
41 1E4E ADP 0.0003801 0.43152 5.10638
42 1E4E PHY 0.003025 0.408 5.10638
43 3B96 MYA 0.002253 0.40094 5.10638
44 3UCJ AZM 0.005815 0.41464 5.28634
45 4AQL TXC 0.0002621 0.44192 5.53191
46 3DGB MUC 0.00248 0.41999 5.53191
47 1Z4V DAN 0.003539 0.41399 5.53191
48 1S8F GDP 0.004485 0.40574 5.64972
49 3D2Y AH0 ALA FGA LYS 0.001042 0.41632 5.95745
50 4GO7 THR 0.008148 0.4041 6
51 2P4Q FLC 0.009332 0.42136 6.38298
52 2XNJ FAD 0.01213 0.40597 6.38298
53 3DX5 DHB 0.009176 0.40203 6.38298
54 2C31 TZD 0.004999 0.41689 6.80851
55 2C31 ADP 0.007807 0.40928 6.80851
56 1H2B OCA 0.01354 0.40875 6.80851
57 3RGG AIR 0.00261 0.42392 6.91824
58 2Q9U FMN 0.0009018 0.41849 7.23404
59 3SQG TP7 0.001825 0.41605 7.23404
60 3A2Q ACA ACA 0.003887 0.40012 7.65957
61 3ANK NG6 GCD 0.004866 0.41308 8.08511
62 3VPQ GSH 0.00456 0.42963 8.33333
63 2C2A ADP 0.001385 0.41612 8.51064
64 1A8S PPI 0.00693 0.40475 8.51064
65 1R5A GTS 0.006866 0.41165 9.17431
66 3QP4 HL0 0.002556 0.41068 9.34066
67 4NM5 ADP 0.0004367 0.41688 10.2128
68 3UIE ANP 0.004105 0.41604 11
69 3UIE ADX 0.003083 0.41189 11
70 1NP0 NGT 0.01216 0.41611 11.4894
71 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.005484 0.44517 17.0068
72 1DL7 NCH 0.02817 0.43104 19.6429
73 3MTW M3R 0.002938 0.40846 20
74 1H2K OGA 0.005973 0.43022 21.9512
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