Receptor
PDB id Resolution Class Description Source Keywords
4PAH 2 Å EC: 1.14.16.1 HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH ADRENALINE INHIBITOR HOMO SAPIENS NON-HEME IRON-CONTAINING MONOOXYGENASE OXIDOREDUCTASE MONO
Ref.: CRYSTALLOGRAPHIC ANALYSIS OF THE HUMAN PHENYLALANIN HYDROXYLASE CATALYTIC DOMAIN WITH BOUND CATECHOL IN AT 2.0 A RESOLUTION. BIOCHEMISTRY V. 37 15638 1998
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FE A:425;
Part of Protein;
none;
submit data
55.845 Fe [Fe+3...
LNR A:600;
Valid;
none;
submit data
169.178 C8 H11 N O3 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4ANP 2.11 Å EC: 1.14.16.1 CRYSTAL STRUCTURE OF HUMAN PHENYLALANINE HYDROXYLASE IN COMPLEX WITH A PHARMACOLOGICAL CHAPERONE HOMO SAPIENS OXIDOREDUCTASE PHENYLKETONURIA FOLDING MECHANISM
Ref.: STRUCTURAL AND MECHANISTIC BASIS OF THE INTERACTION A PHARMACOLOGICAL CHAPERONE AND HUMAN PHENYLALANINE HYDROXYLASE. CHEMBIOCHEM V. 13 1266 2012
Members (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1TG2 - H2B C9 H13 N5 O3 C[C@@H]([C....
2 1J8U - H4B C9 H15 N5 O3 C[C@@H]([C....
3 1MMT - H4B C9 H15 N5 O3 C[C@@H]([C....
4 1LRM - HBI C9 H13 N5 O3 C[C@@H]([C....
5 1DMW - HBI C9 H13 N5 O3 C[C@@H]([C....
6 1KW0 - H4B C9 H15 N5 O3 C[C@@H]([C....
7 6PAH - DAH C9 H11 N O4 c1cc(c(cc1....
8 1MMK - H4B C9 H15 N5 O3 C[C@@H]([C....
9 5PAH - LDP C8 H11 N O2 c1cc(c(cc1....
10 4ANP Ki = 200 uM 3QI C14 H13 N3 O S2 Cc1ccnc(c1....
11 3PAH - XDE C9 H13 N O3 CNC[C@H](c....
12 4PAH - LNR C8 H11 N O3 c1cc(c(cc1....
70% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1TG2 - H2B C9 H13 N5 O3 C[C@@H]([C....
2 1J8U - H4B C9 H15 N5 O3 C[C@@H]([C....
3 1MMT - H4B C9 H15 N5 O3 C[C@@H]([C....
4 1LRM - HBI C9 H13 N5 O3 C[C@@H]([C....
5 1DMW - HBI C9 H13 N5 O3 C[C@@H]([C....
6 1KW0 - H4B C9 H15 N5 O3 C[C@@H]([C....
7 6PAH - DAH C9 H11 N O4 c1cc(c(cc1....
8 1MMK - H4B C9 H15 N5 O3 C[C@@H]([C....
9 5PAH - LDP C8 H11 N O2 c1cc(c(cc1....
10 4ANP Ki = 200 uM 3QI C14 H13 N3 O S2 Cc1ccnc(c1....
11 3PAH - XDE C9 H13 N O3 CNC[C@H](c....
12 4PAH - LNR C8 H11 N O3 c1cc(c(cc1....
13 3HF6 ic50 = 0.026 uM LX0 C24 H24 N6 O2 C[C@H](c1c....
14 5TPG ic50 = 14 nM 7H5 C28 H29 Cl F3 N5 O5 S CS(=O)(=O)....
15 3HF8 Ki = 0.31 uM ML0 C27 H22 F4 N4 O3 c1cc(cc(c1....
16 3HFB Ki = 0.03 uM ML4 C27 H26 N4 O2 Cc1ccccc1c....
17 5J6D ic50 = 6 nM 6H5 C30 H35 N5 O5 [H]/N=C(/N....
18 1MLW - HBI C9 H13 N5 O3 C[C@@H]([C....
19 2TOH Ki = 70 uM HBI C9 H13 N5 O3 C[C@@H]([C....
50% Homology Family (20)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1TG2 - H2B C9 H13 N5 O3 C[C@@H]([C....
2 1J8U - H4B C9 H15 N5 O3 C[C@@H]([C....
3 1MMT - H4B C9 H15 N5 O3 C[C@@H]([C....
4 1LRM - HBI C9 H13 N5 O3 C[C@@H]([C....
5 1DMW - HBI C9 H13 N5 O3 C[C@@H]([C....
6 1KW0 - H4B C9 H15 N5 O3 C[C@@H]([C....
7 6PAH - DAH C9 H11 N O4 c1cc(c(cc1....
8 1MMK - H4B C9 H15 N5 O3 C[C@@H]([C....
9 5PAH - LDP C8 H11 N O2 c1cc(c(cc1....
10 4ANP Ki = 200 uM 3QI C14 H13 N3 O S2 Cc1ccnc(c1....
11 3PAH - XDE C9 H13 N O3 CNC[C@H](c....
12 4PAH - LNR C8 H11 N O3 c1cc(c(cc1....
13 3HF6 ic50 = 0.026 uM LX0 C24 H24 N6 O2 C[C@H](c1c....
14 5TPG ic50 = 14 nM 7H5 C28 H29 Cl F3 N5 O5 S CS(=O)(=O)....
15 3HF8 Ki = 0.31 uM ML0 C27 H22 F4 N4 O3 c1cc(cc(c1....
16 3HFB Ki = 0.03 uM ML4 C27 H26 N4 O2 Cc1ccccc1c....
17 5J6D ic50 = 6 nM 6H5 C30 H35 N5 O5 [H]/N=C(/N....
18 1MLW - HBI C9 H13 N5 O3 C[C@@H]([C....
19 5L01 ic50 = 33 nM 6Z4 C27 H27 Cl F3 N5 O3 c1ccc(cc1)....
20 2TOH Ki = 70 uM HBI C9 H13 N5 O3 C[C@@H]([C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: LNR; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 LNR 1 1
2 ALE 0.552632 0.823529
3 XDE 0.552632 0.823529
4 5FW 0.525 0.823529
5 OTR 0.432432 0.862069
Similar Ligands (3D)
Ligand no: 1; Ligand: LNR; Similar ligands found: 1504
No: Ligand Similarity coefficient
1 L99 0.9991
2 INO 0.9755
3 4SX 0.9742
4 4NC 0.9727
5 J9T 0.9712
6 93K 0.9704
7 DHB 0.9702
8 LDP 0.9696
9 2HO 0.9673
10 VXX 0.9667
11 P9P 0.9664
12 069 0.9660
13 CHB 0.9654
14 MYJ 0.9652
15 45L 0.9642
16 HDH 0.9631
17 X0V 0.9629
18 9TW 0.9617
19 H4E 0.9601
20 IHB 0.9600
21 QSB 0.9587
22 42J 0.9582
23 IFP 0.9572
24 XX2 0.9565
25 F4E 0.9563
26 EKZ 0.9550
27 ISZ 0.9533
28 7MU 0.9525
29 DHY 0.9522
30 GJZ 0.9516
31 PH3 0.9509
32 JLZ 0.9485
33 BHO 0.9484
34 GDE 0.9480
35 4P5 0.9479
36 ASC 0.9478
37 NIZ 0.9477
38 0HO 0.9473
39 3A9 0.9473
40 DHK 0.9472
41 4FH 0.9468
42 8WO 0.9468
43 AC6 0.9468
44 EDR 0.9467
45 92P 0.9465
46 3LR 0.9456
47 XIY 0.9453
48 CFI 0.9453
49 PHB 0.9450
50 HC4 0.9449
51 4FA 0.9443
52 ODO 0.9442
53 KTA 0.9441
54 VNL 0.9437
55 NPO 0.9437
56 1M2 0.9436
57 M4E 0.9435
58 2LY 0.9434
59 A29 0.9434
60 6NT 0.9433
61 GAB 0.9429
62 C2Y 0.9428
63 L5V 0.9427
64 MNN 0.9427
65 1DJ 0.9427
66 PAB 0.9423
67 1A7 0.9420
68 1F1 0.9415
69 7MX 0.9414
70 R20 0.9414
71 2ZM 0.9414
72 H7Y 0.9413
73 SAF 0.9413
74 DHS 0.9411
75 BZ2 0.9410
76 HQJ 0.9409
77 3OC 0.9408
78 3PF 0.9407
79 BNF 0.9406
80 EGR 0.9406
81 3NT 0.9404
82 6FZ 0.9402
83 LT2 0.9400
84 3HB 0.9400
85 SHA 0.9399
86 4AA 0.9398
87 2FY 0.9397
88 HHH 0.9397
89 MSR 0.9397
90 MPV 0.9393
91 0HN 0.9392
92 EOL 0.9386
93 5NI 0.9386
94 ABI 0.9386
95 GZL 0.9386
96 JAW 0.9385
97 AEH 0.9384
98 I1E 0.9383
99 BDP 0.9382
100 4J8 0.9382
101 N2I 0.9381
102 3C4 0.9380
103 YRL 0.9379
104 4ZA 0.9378
105 QBM 0.9377
106 PBZ 0.9377
107 QSH 0.9375
108 4A3 0.9373
109 FCR 0.9371
110 AEF 0.9370
111 PHE 0.9370
112 3NY 0.9368
113 FHB 0.9366
114 KOJ 0.9362
115 OVV 0.9360
116 NNO 0.9358
117 3HM 0.9355
118 ESP 0.9355
119 4Z4 0.9351
120 FEH 0.9350
121 6TZ 0.9347
122 HBD 0.9346
123 268 0.9344
124 53C 0.9344
125 3QM 0.9343
126 J0Z 0.9343
127 T9G 0.9343
128 6NI 0.9343
129 E7S 0.9343
130 ZXD 0.9340
131 M4T 0.9340
132 SAN 0.9339
133 WCE 0.9339
134 F31 0.9336
135 DOB 0.9335
136 JB8 0.9334
137 JDN 0.9334
138 HA5 0.9333
139 TAG 0.9332
140 4XV 0.9328
141 MS9 0.9327
142 TSU 0.9327
143 0JD 0.9326
144 I3E 0.9326
145 4MA 0.9326
146 E7Z 0.9325
147 CPZ 0.9322
148 9R5 0.9321
149 IWT 0.9321
150 8XL 0.9320
151 MR1 0.9319
152 4HP 0.9317
153 4WL 0.9317
154 SKM 0.9315
155 M5H 0.9312
156 263 0.9312
157 PRZ 0.9311
158 PZI 0.9311
159 FBS 0.9311
160 HQD 0.9307
161 UFV 0.9307
162 YTX 0.9306
163 7VP 0.9306
164 J6W 0.9306
165 ICO 0.9305
166 P72 0.9305
167 MXN 0.9305
168 61M 0.9304
169 258 0.9302
170 8ZE 0.9302
171 BZ3 0.9302
172 UNJ 0.9302
173 9ZE 0.9301
174 F9P 0.9301
175 DHC 0.9301
176 4CS 0.9301
177 RBJ 0.9300
178 N1E 0.9299
179 A5E 0.9299
180 QY9 0.9299
181 KJU 0.9297
182 1QP 0.9296
183 B40 0.9296
184 8WT 0.9296
185 PPY 0.9296
186 0F9 0.9295
187 2AL 0.9295
188 NYL 0.9293
189 1Y6 0.9292
190 JND 0.9291
191 MAJ 0.9291
192 TYL 0.9291
193 M3H 0.9290
194 5QY 0.9290
195 FBM 0.9290
196 GVG 0.9290
197 J9N 0.9290
198 FA1 0.9289
199 Z82 0.9289
200 5CU 0.9289
201 ESX 0.9289
202 BCU 0.9288
203 ASO 0.9288
204 3AB 0.9288
205 5OB 0.9287
206 FUD 0.9285
207 2BG 0.9285
208 TSS 0.9284
209 SMN 0.9284
210 9FL 0.9284
211 0P6 0.9284
212 173 0.9281
213 ICB 0.9280
214 AMS 0.9280
215 3HA 0.9279
216 ONR 0.9278
217 5RO 0.9278
218 XXG 0.9278
219 SVD 0.9278
220 S2P 0.9270
221 BNL 0.9269
222 FA0 0.9268
223 4ME 0.9267
224 JFJ 0.9266
225 264 0.9261
226 D48 0.9260
227 RJY 0.9259
228 SW7 0.9257
229 8NB 0.9257
230 4JQ 0.9255
231 E35 0.9254
232 DE5 0.9252
233 36Y 0.9251
234 PO6 0.9250
235 PAC 0.9250
236 FK8 0.9247
237 3ZB 0.9247
238 J5I 0.9246
239 51R 0.9246
240 AEG 0.9245
241 G3E 0.9245
242 HX3 0.9244
243 BHA 0.9244
244 36E 0.9243
245 FBW 0.9242
246 4YO 0.9242
247 SE2 0.9241
248 AKG 0.9241
249 4XS 0.9239
250 K5W 0.9238
251 5XC 0.9237
252 3Z8 0.9237
253 717 0.9236
254 R9S 0.9235
255 15E 0.9235
256 OGA 0.9235
257 ANN 0.9235
258 HCI 0.9234
259 BEZ 0.9231
260 FBV 0.9230
261 A09 0.9228
262 N2Z 0.9227
263 5QX 0.9227
264 PRA 0.9223
265 FF2 0.9222
266 2A9 0.9220
267 GRO 0.9220
268 TZF 0.9219
269 TYE 0.9219
270 PPT 0.9219
271 ZZ2 0.9215
272 TSR 0.9214
273 94W 0.9213
274 5RG 0.9213
275 HX4 0.9212
276 CXP 0.9212
277 PNZ 0.9210
278 6RQ 0.9210
279 CH9 0.9208
280 ES2 0.9208
281 TTL 0.9208
282 269 0.9207
283 4HM 0.9206
284 URS 0.9206
285 YOF 0.9206
286 FAN 0.9206
287 5NU 0.9206
288 HNL 0.9205
289 3HP 0.9205
290 8U3 0.9203
291 EUG 0.9203
292 GTQ 0.9203
293 2HQ 0.9202
294 L22 0.9202
295 9BF 0.9202
296 5GU 0.9201
297 XCZ 0.9200
298 92K 0.9199
299 4M0 0.9199
300 428 0.9198
301 52C 0.9198
302 PHU 0.9197
303 PIY 0.9196
304 DBH 0.9195
305 23J 0.9195
306 535 0.9195
307 PIM 0.9193
308 3BZ 0.9193
309 5RN 0.9192
310 6PC 0.9192
311 SNU 0.9189
312 4M4 0.9188
313 15N 0.9187
314 HIS 0.9187
315 2O6 0.9186
316 OMD 0.9186
317 KTW 0.9185
318 R2P 0.9184
319 1P8 0.9184
320 PH2 0.9180
321 N9J 0.9179
322 FB1 0.9177
323 HNK 0.9175
324 JTH 0.9175
325 I3A 0.9175
326 V55 0.9174
327 TGX 0.9174
328 ENO 0.9174
329 D8Q 0.9173
330 7OD 0.9173
331 XDK 0.9173
332 N3W 0.9173
333 CS2 0.9172
334 MPK 0.9172
335 X0U 0.9170
336 SS2 0.9169
337 IAC 0.9168
338 CN0 0.9167
339 5M0 0.9167
340 X48 0.9166
341 7N0 0.9165
342 AAS 0.9163
343 4XR 0.9163
344 IYR 0.9163
345 REL 0.9161
346 363 0.9159
347 TT4 0.9159
348 PJW 0.9159
349 XM0 0.9157
350 BEN 0.9157
351 B3U 0.9155
352 0LH 0.9155
353 NMJ 0.9155
354 8OZ 0.9155
355 4VY 0.9154
356 LYL 0.9154
357 TPA 0.9154
358 9RW 0.9153
359 N7I 0.9153
360 AMH 0.9153
361 8W9 0.9153
362 M2K 0.9151
363 DHR 0.9150
364 EXD 0.9150
365 JXZ 0.9150
366 FGZ 0.9150
367 PBC 0.9150
368 3M0 0.9149
369 GO2 0.9149
370 ZZZ 0.9149
371 YPN 0.9147
372 PBA 0.9147
373 KBB 0.9147
374 DEE 0.9147
375 G4D 0.9145
376 GZQ 0.9145
377 CWJ 0.9145
378 BE2 0.9144
379 3IT 0.9143
380 GCU 0.9140
381 QMP 0.9139
382 PEA 0.9139
383 6Q3 0.9138
384 NCT 0.9138
385 R8V 0.9138
386 EN1 0.9135
387 QUS 0.9134
388 M6Z 0.9132
389 C1M 0.9131
390 DEW 0.9131
391 AX3 0.9131
392 ORO 0.9131
393 EYK 0.9131
394 HPS 0.9130
395 P58 0.9129
396 BNS 0.9127
397 QIC 0.9127
398 3FH 0.9127
399 97T 0.9126
400 ISD 0.9125
401 HY1 0.9125
402 AOS 0.9124
403 4BY 0.9124
404 XX3 0.9123
405 ADA 0.9123
406 EVA 0.9123
407 UNU 0.9123
408 HBA 0.9122
409 DIR 0.9121
410 GF4 0.9121
411 ESI 0.9121
412 36M 0.9121
413 2LP 0.9120
414 2EC 0.9120
415 A13 0.9120
416 EMZ 0.9119
417 AMR 0.9117
418 PSJ 0.9117
419 54G 0.9117
420 F9Y 0.9116
421 DQA 0.9116
422 NCA 0.9115
423 GYE 0.9114
424 EYV 0.9113
425 F0J 0.9113
426 SAL 0.9113
427 9TZ 0.9111
428 MTL 0.9108
429 KTJ 0.9107
430 HIC 0.9107
431 BGC 0.9107
432 SLS 0.9106
433 TLM 0.9105
434 JRB 0.9104
435 0N7 0.9104
436 9FE 0.9104
437 BAM 0.9104
438 HFA 0.9103
439 4V2 0.9103
440 SRO 0.9102
441 RSO 0.9101
442 AAN 0.9100
443 GZ2 0.9100
444 HJH 0.9100
445 N8Y 0.9099
446 NDH 0.9099
447 TWO 0.9098
448 AL0 0.9097
449 KDV 0.9097
450 GTR 0.9097
451 CK2 0.9097
452 ES6 0.9097
453 SD4 0.9096
454 O2A 0.9096
455 IPB 0.9096
456 NIO 0.9096
457 PMB 0.9096
458 KUF 0.9095
459 TYR 0.9095
460 QBS 0.9094
461 0FK 0.9093
462 FB2 0.9093
463 LPK 0.9091
464 XIZ 0.9091
465 92G 0.9090
466 44V 0.9090
467 OXC 0.9089
468 MXD 0.9088
469 GLU 0.9088
470 RM1 0.9087
471 J9Q 0.9087
472 FA3 0.9087
473 ARP 0.9086
474 SYV 0.9086
475 CWS 0.9086
476 NVU 0.9085
477 CTS 0.9085
478 BPY 0.9083
479 3F0 0.9083
480 7ME 0.9083
481 5LA 0.9082
482 IOP 0.9082
483 7B4 0.9082
484 1LQ 0.9082
485 NFM 0.9080
486 8GC 0.9080
487 HNH 0.9080
488 0W1 0.9080
489 PZA 0.9080
490 Q88 0.9079
491 GLC 0.9079
492 SQV 0.9077
493 BP7 0.9077
494 R67 0.9076
495 2HU 0.9075
496 DGJ 0.9075
497 B62 0.9075
498 IV2 0.9074
499 C9E 0.9073
500 15L 0.9073
501 FP1 0.9073
502 3AL 0.9073
503 IP0 0.9073
504 1KP 0.9072
505 AY4 0.9071
506 RMN 0.9071
507 2FX 0.9071
508 XQI 0.9071
509 GWM 0.9071
510 NOJ 0.9071
511 GLO 0.9070
512 HL5 0.9070
513 E1P 0.9070
514 DOR 0.9070
515 PEL 0.9070
516 12Q 0.9070
517 SS1 0.9070
518 8S0 0.9069
519 4BZ 0.9069
520 TZM 0.9068
521 JZ4 0.9068
522 1X4 0.9067
523 86J 0.9067
524 CIY 0.9067
525 PEP 0.9067
526 CXH 0.9066
527 6ME 0.9066
528 S0G 0.9065
529 RUY 0.9065
530 AJV 0.9065
531 57O 0.9065
532 F4K 0.9065
533 3U4 0.9065
534 HDL 0.9064
535 AS3 0.9064
536 HL4 0.9063
537 1Z6 0.9063
538 JXN 0.9063
539 OAA 0.9063
540 G3F 0.9063
541 4TU 0.9063
542 SRT 0.9062
543 7HQ 0.9061
544 VNJ 0.9061
545 1XA 0.9060
546 M1Z 0.9059
547 P7Y 0.9059
548 8NX 0.9059
549 1P3 0.9058
550 4ZD 0.9056
551 DGN 0.9056
552 1L5 0.9056
553 12T 0.9055
554 7WR 0.9055
555 H42 0.9054
556 APS 0.9054
557 6KT 0.9054
558 4PN 0.9053
559 NBZ 0.9052
560 SN4 0.9051
561 GXY 0.9051
562 7C3 0.9050
563 Q6T 0.9050
564 OVM 0.9050
565 GOJ 0.9049
566 B85 0.9048
567 34D 0.9047
568 3MB 0.9047
569 PBN 0.9046
570 1P7 0.9046
571 IF7 0.9045
572 JF6 0.9045
573 4I8 0.9045
574 R9Y 0.9045
575 F52 0.9045
576 42C 0.9045
577 PKU 0.9044
578 CXF 0.9044
579 SKA 0.9044
580 GJP 0.9044
581 DNF 0.9042
582 MMS 0.9041
583 826 0.9041
584 3ID 0.9041
585 HIO 0.9040
586 IOS 0.9040
587 261 0.9040
588 M1Q 0.9040
589 E5X 0.9040
590 KF5 0.9039
591 5MK 0.9039
592 1IT 0.9038
593 MWP 0.9037
594 FE DB1 0.9036
595 YZM 0.9036
596 KMY 0.9036
597 XCG 0.9035
598 9PY 0.9035
599 QX4 0.9035
600 D1X 0.9034
601 OHP 0.9033
602 FBU 0.9033
603 M78 0.9030
604 ZON 0.9030
605 2HC 0.9030
606 CEE 0.9030
607 ASP 0.9030
608 TMG 0.9030
609 TOF 0.9029
610 DQU 0.9029
611 LFC 0.9028
612 PRY 0.9027
613 GAL 0.9027
614 O45 0.9026
615 40E 0.9026
616 PRF 0.9026
617 V1T 0.9026
618 HHA 0.9024
619 MQN 0.9024
620 LMR 0.9024
621 6J9 0.9023
622 5B1 0.9023
623 AW5 0.9022
624 BSX 0.9021
625 BQ2 0.9021
626 4JT 0.9021
627 8GK 0.9020
628 3VX 0.9020
629 VOH 0.9019
630 CK1 0.9019
631 M45 0.9019
632 HHR 0.9019
633 RHU 0.9019
634 GCS 0.9018
635 GO8 0.9017
636 DBX 0.9016
637 S24 0.9015
638 CWM 0.9015
639 L14 0.9015
640 LYS 0.9015
641 9UL 0.9014
642 SOR 0.9013
643 MLT 0.9013
644 APG 0.9013
645 1WC 0.9013
646 9CA 0.9012
647 DAH 0.9011
648 DX3 0.9011
649 2FQ 0.9010
650 ZME 0.9008
651 DPN 0.9007
652 6M4 0.9006
653 MNP 0.9005
654 EV0 0.9004
655 QSC 0.9004
656 M4S 0.9004
657 K7M 0.9003
658 MJ2 0.9003
659 4VP 0.9002
660 AHR 0.9002
661 4LW 0.9002
662 URC 0.9002
663 3XX 0.9001
664 KKN 0.9000
665 TIU 0.9000
666 SOE 0.9000
667 FOT 0.8999
668 0BP 0.8998
669 BZX 0.8998
670 B4O 0.8997
671 FOC 0.8997
672 F05 0.8997
673 KMH 0.8996
674 S8V 0.8995
675 X05 0.8995
676 TH7 0.8995
677 BPW 0.8994
678 LEU 0.8994
679 1SA 0.8994
680 IFL 0.8993
681 CFA 0.8993
682 NF3 0.8993
683 BRT 0.8992
684 MRW 0.8992
685 TRP 0.8992
686 FDR 0.8991
687 TCA 0.8989
688 XQ0 0.8989
689 2HG 0.8988
690 293 0.8988
691 DIN 0.8988
692 DC5 0.8987
693 RAT 0.8987
694 5WZ 0.8987
695 ES7 0.8987
696 271 0.8987
697 HPP 0.8987
698 EVF 0.8986
699 S2G 0.8986
700 KDG 0.8983
701 GLN 0.8983
702 JZ7 0.8983
703 6CS 0.8983
704 B09 0.8982
705 AZ9 0.8982
706 2F6 0.8981
707 COU 0.8981
708 DMD 0.8981
709 HGA 0.8980
710 0TU 0.8980
711 M3P 0.8980
712 NFA 0.8980
713 ISN 0.8980
714 S8D 0.8978
715 B41 0.8978
716 BZE 0.8976
717 SDD 0.8976
718 B2J 0.8976
719 2BX 0.8976
720 7W1 0.8976
721 IJZ 0.8976
722 2IT 0.8975
723 GGL 0.8975
724 DAL DAL 0.8975
725 BPN 0.8975
726 FHC 0.8974
727 SOL 0.8973
728 3BU 0.8973
729 E1T 0.8972
730 PD2 0.8972
731 0W8 0.8972
732 3HG 0.8971
733 4FS 0.8971
734 SQ4 0.8971
735 JKE 0.8971
736 8TX 0.8971
737 6ZX 0.8970
738 4NM 0.8970
739 LT1 0.8969
740 3SL 0.8969
741 AOT 0.8968
742 ES5 0.8968
743 42A 0.8968
744 HQT 0.8968
745 PTU 0.8967
746 3SK 0.8967
747 SYC 0.8966
748 1LN 0.8966
749 GCB 0.8965
750 GLF 0.8965
751 HF2 0.8965
752 BZJ 0.8965
753 1VK 0.8964
754 ET2 0.8964
755 OW4 0.8964
756 7MW 0.8963
757 5HN 0.8963
758 5WV 0.8963
759 HSO 0.8963
760 A9P 0.8960
761 BRH 0.8960
762 46P 0.8960
763 COI 0.8960
764 54X 0.8959
765 2QC 0.8959
766 C2U 0.8959
767 KGK 0.8959
768 505 0.8958
769 ES0 0.8958
770 D3G 0.8958
771 G2F 0.8958
772 NTN 0.8957
773 K97 0.8957
774 F69 0.8956
775 449 0.8956
776 EYJ 0.8956
777 M58 0.8956
778 NAG 0.8954
779 JG8 0.8953
780 I2E 0.8952
781 4JC 0.8952
782 FBB 0.8952
783 LZM 0.8951
784 XRX 0.8951
785 AJY 0.8951
786 7MK 0.8951
787 SQ7 0.8949
788 RNO 0.8949
789 56D 0.8948
790 03V 0.8948
791 7VS 0.8948
792 9MG 0.8948
793 L13 0.8946
794 OCH 0.8946
795 5WU 0.8945
796 LL1 0.8945
797 YCP 0.8945
798 TEO 0.8943
799 PZM 0.8942
800 463 0.8942
801 KT7 0.8942
802 ONH 0.8941
803 GUA 0.8941
804 A7W 0.8940
805 AHC 0.8940
806 K34 0.8940
807 FBA 0.8939
808 PA1 0.8939
809 ZYR 0.8939
810 AX7 0.8938
811 3DO 0.8937
812 DS0 0.8937
813 JYB 0.8937
814 SKF 0.8936
815 30G 0.8936
816 SHI 0.8935
817 2AQ 0.8935
818 PDC 0.8935
819 LCN 0.8934
820 259 0.8933
821 TTY 0.8931
822 XBT 0.8931
823 SX1 0.8931
824 9KH 0.8931
825 N4B 0.8930
826 Z5P 0.8930
827 SNO 0.8930
828 2K8 0.8930
829 A7H 0.8929
830 JB5 0.8929
831 HMH 0.8929
832 M74 0.8928
833 DGL 0.8928
834 50C 0.8927
835 8CM 0.8926
836 AHN 0.8925
837 N91 0.8925
838 SJ5 0.8924
839 QWN 0.8924
840 MET 0.8924
841 C2B 0.8924
842 VGD 0.8924
843 VGL 0.8924
844 4HC 0.8924
845 Y3L 0.8924
846 RD4 0.8923
847 1AL 0.8923
848 F1A 0.8923
849 80G 0.8922
850 OOG 0.8922
851 DHI 0.8922
852 3CR 0.8922
853 4RU 0.8921
854 174 0.8921
855 SBK 0.8920
856 TZL 0.8920
857 NOY 0.8919
858 DAS 0.8919
859 UN1 0.8919
860 39O 0.8919
861 OW7 0.8918
862 K2T 0.8918
863 0NX 0.8917
864 3R6 0.8917
865 SR1 0.8917
866 KJH 0.8916
867 5XB 0.8915
868 ORN 0.8914
869 Q24 0.8914
870 CTL 0.8913
871 GZ3 0.8913
872 FYU 0.8912
873 P80 0.8912
874 M0W 0.8912
875 FQI 0.8911
876 13P 0.8911
877 2C2 0.8910
878 FTV 0.8910
879 149 0.8910
880 KBG 0.8910
881 NPA 0.8909
882 CUW 0.8909
883 LSQ 0.8909
884 2CZ 0.8908
885 152 0.8908
886 PQ0 0.8908
887 X8Z 0.8907
888 6VD 0.8907
889 HQ9 0.8907
890 OK7 0.8907
891 A3M 0.8907
892 AKH 0.8906
893 0FN 0.8906
894 JXW 0.8904
895 PEQ 0.8904
896 PMF 0.8904
897 41K 0.8903
898 AMQ 0.8903
899 DRL 0.8903
900 LGC 0.8903
901 5VM 0.8902
902 MOK 0.8901
903 TIH 0.8901
904 24W 0.8901
905 M6H 0.8900
906 82I 0.8900
907 4XF 0.8900
908 2FG 0.8900
909 ALL 0.8900
910 RNT 0.8899
911 Q02 0.8899
912 UAN 0.8899
913 FBT 0.8899
914 7BC 0.8898
915 DA4 0.8897
916 XXP 0.8897
917 DYA 0.8896
918 3YP 0.8895
919 M5E 0.8895
920 PQK 0.8895
921 JF2 0.8894
922 SYM 0.8893
923 KMT 0.8893
924 GT4 0.8893
925 2H5 0.8893
926 2UB 0.8892
927 NGT 0.8892
928 TLA 0.8892
929 TL6 0.8891
930 SSB 0.8890
931 RNS 0.8890
932 GLA 0.8890
933 6DP 0.8889
934 INE 0.8888
935 W29 0.8887
936 GAF 0.8887
937 PXL 0.8887
938 X6X 0.8884
939 4SV 0.8883
940 MO8 0.8883
941 4JL 0.8883
942 QXW 0.8882
943 0XT 0.8882
944 X09 0.8882
945 1BN 0.8881
946 DI6 0.8881
947 5VL 0.8881
948 M1H 0.8881
949 QH3 0.8880
950 4LV 0.8879
951 49F 0.8877
952 FBJ 0.8877
953 2CK 0.8877
954 WOO 0.8876
955 P81 0.8876
956 F12 0.8876
957 URO 0.8875
958 3VW 0.8875
959 DHQ 0.8875
960 HHS 0.8874
961 BK9 0.8872
962 6OT 0.8872
963 HNM 0.8872
964 GVY 0.8872
965 DTY 0.8871
966 67N 0.8871
967 AFR 0.8871
968 CFF 0.8871
969 1HN 0.8868
970 AH8 0.8868
971 KBZ 0.8868
972 KJY 0.8868
973 27B 0.8867
974 ETV 0.8865
975 UFO 0.8865
976 44W 0.8864
977 HA7 0.8864
978 3TC 0.8862
979 3R4 0.8862
980 LTT 0.8861
981 TYC 0.8858
982 JBK 0.8857
983 HXX 0.8857
984 2KA 0.8857
985 AES 0.8855
986 OVP 0.8855
987 2MI 0.8854
988 7Q1 0.8854
989 L7T 0.8854
990 HKD 0.8854
991 ASN 0.8853
992 AC0 0.8851
993 7O4 0.8850
994 K4V 0.8850
995 8HC 0.8850
996 DE3 0.8850
997 NDG 0.8850
998 DJN 0.8849
999 GCO 0.8849
1000 S0E 0.8849
1001 4NB 0.8849
1002 I4B 0.8848
1003 DNC 0.8848
1004 9H2 0.8847
1005 5DS 0.8847
1006 ATX 0.8846
1007 NQH 0.8846
1008 2PG 0.8846
1009 6HO 0.8845
1010 36R 0.8845
1011 NBG 0.8844
1012 ZBT 0.8844
1013 PFF 0.8843
1014 4BL 0.8843
1015 LAO 0.8843
1016 CLZ 0.8843
1017 MQB 0.8842
1018 GXL 0.8841
1019 CCV 0.8840
1020 33S 0.8839
1021 A9O 0.8839
1022 LJ3 0.8839
1023 1WD 0.8839
1024 X0W 0.8838
1025 SWA 0.8838
1026 8H8 0.8837
1027 OQC 0.8837
1028 B57 0.8837
1029 HPT 0.8836
1030 HBO 0.8836
1031 2D0 0.8835
1032 Q03 0.8835
1033 DIU 0.8835
1034 ABF 0.8834
1035 SME 0.8834
1036 AN3 0.8834
1037 M1A 0.8833
1038 7B3 0.8833
1039 CLW 0.8832
1040 3PG 0.8832
1041 ROI 0.8831
1042 GIV 0.8831
1043 M3E 0.8830
1044 IT2 0.8830
1045 ABV 0.8828
1046 0FO 0.8828
1047 BEA 0.8827
1048 7WG 0.8827
1049 32X 0.8825
1050 JAE 0.8824
1051 NOK 0.8823
1052 QPR 0.8823
1053 94B 0.8823
1054 EA1 0.8823
1055 JZA 0.8822
1056 E4P 0.8822
1057 6HX 0.8821
1058 49O 0.8821
1059 B2Y 0.8821
1060 HXY 0.8820
1061 FER 0.8820
1062 24B 0.8820
1063 6SD 0.8819
1064 2D8 0.8818
1065 4Z3 0.8818
1066 1U6 0.8818
1067 RB5 0.8818
1068 TB8 0.8817
1069 7W4 0.8817
1070 270 0.8816
1071 3QO 0.8816
1072 RP5 0.8816
1073 MBG 0.8813
1074 GLT 0.8812
1075 B1J 0.8811
1076 TAR 0.8811
1077 4JM 0.8810
1078 SYR 0.8809
1079 C82 0.8809
1080 DFB 0.8809
1081 4TB 0.8808
1082 6QF 0.8808
1083 BNT 0.8808
1084 RKV 0.8807
1085 ES9 0.8803
1086 3Y7 0.8803
1087 XHP 0.8803
1088 2V0 0.8801
1089 XUL 0.8799
1090 JF1 0.8799
1091 0OL 0.8799
1092 1GN 0.8799
1093 L46 0.8798
1094 KJM 0.8798
1095 HHI 0.8798
1096 HPA 0.8798
1097 SHG 0.8797
1098 1SQ 0.8795
1099 GV9 0.8795
1100 DDU 0.8794
1101 J9W 0.8794
1102 4KL 0.8794
1103 091 0.8793
1104 1DV 0.8793
1105 NSP 0.8792
1106 YIE 0.8792
1107 977 0.8791
1108 F06 0.8791
1109 H8N 0.8790
1110 MIL 0.8789
1111 KP6 0.8788
1112 NLE 0.8788
1113 G5V 0.8788
1114 4MU 0.8787
1115 5NE 0.8786
1116 SYA 0.8786
1117 54D 0.8785
1118 4BF 0.8785
1119 NGW 0.8785
1120 PEY 0.8785
1121 SYE 0.8784
1122 492 0.8783
1123 5NS 0.8783
1124 MZB 0.8782
1125 2AK 0.8782
1126 6R8 0.8781
1127 MCO 0.8781
1128 5WY 0.8780
1129 HMU 0.8780
1130 SEP 0.8779
1131 9W5 0.8777
1132 CC5 0.8777
1133 DTR 0.8776
1134 9GP 0.8776
1135 NLA 0.8776
1136 209 0.8776
1137 28N 0.8776
1138 MUA 0.8775
1139 5F5 0.8775
1140 IFM 0.8775
1141 HLZ 0.8775
1142 C2A 0.8773
1143 MAQ 0.8772
1144 JA8 0.8772
1145 1NP 0.8772
1146 XFE 0.8771
1147 7QS 0.8771
1148 OTW 0.8770
1149 2FT 0.8769
1150 5MI 0.8769
1151 P84 0.8769
1152 EUE 0.8769
1153 8IG 0.8769
1154 7WV 0.8768
1155 FH2 0.8768
1156 SYG 0.8768
1157 5O6 0.8768
1158 SG2 0.8767
1159 0V5 0.8767
1160 MPP 0.8766
1161 6M9 0.8766
1162 75K 0.8766
1163 LZ2 0.8765
1164 B55 0.8764
1165 SLC 0.8763
1166 BP3 0.8762
1167 CIT 0.8761
1168 MVN 0.8761
1169 6XI 0.8761
1170 H4N 0.8760
1171 XAZ 0.8760
1172 5MB 0.8759
1173 NCD 0.8759
1174 14W 0.8758
1175 3QV 0.8758
1176 QBK 0.8758
1177 68A 0.8757
1178 RBL 0.8756
1179 SDF 0.8756
1180 S0W 0.8755
1181 XYL 0.8755
1182 GRE 0.8755
1183 FK1 0.8754
1184 ANC 0.8754
1185 9RH 0.8753
1186 22L 0.8752
1187 11S 0.8752
1188 MNM 0.8752
1189 GDL 0.8751
1190 CTE 0.8751
1191 1SV 0.8750
1192 C9M 0.8749
1193 SV4 0.8749
1194 F60 0.8749
1195 FWD 0.8748
1196 RA7 0.8747
1197 RIB 0.8747
1198 1LM 0.8747
1199 5H1 0.8746
1200 JBH 0.8746
1201 A7N 0.8745
1202 AHB 0.8745
1203 C53 0.8743
1204 BE7 0.8743
1205 FZM 0.8743
1206 8GL 0.8742
1207 14O 0.8742
1208 XI7 0.8742
1209 GJK 0.8741
1210 1FD 0.8741
1211 F2W 0.8741
1212 OHJ 0.8739
1213 MD6 0.8739
1214 6F0 0.8737
1215 54E 0.8736
1216 H62 0.8736
1217 795 0.8735
1218 XEN 0.8734
1219 2ZQ 0.8734
1220 ES1 0.8732
1221 CLU 0.8731
1222 BTY 0.8730
1223 MP5 0.8730
1224 8K2 0.8730
1225 6M1 0.8730
1226 QDK 0.8729
1227 HSX 0.8729
1228 FDK 0.8727
1229 MZG 0.8725
1230 2K4 0.8725
1231 PCA 0.8725
1232 88L 0.8724
1233 BR9 0.8724
1234 DVQ 0.8724
1235 N5J 0.8724
1236 3DM 0.8724
1237 OA3 0.8724
1238 NGO 0.8723
1239 STX 0.8722
1240 GC3 0.8722
1241 2SX 0.8721
1242 X11 0.8721
1243 27Y 0.8720
1244 0A1 0.8720
1245 89J 0.8719
1246 5JL 0.8717
1247 AIN 0.8716
1248 EHM 0.8715
1249 NPY 0.8715
1250 3MF 0.8715
1251 O72 0.8715
1252 4AV 0.8715
1253 ZEC 0.8715
1254 MEQ 0.8714
1255 P9E 0.8714
1256 1SS 0.8714
1257 6HP 0.8713
1258 UA5 0.8713
1259 5JC 0.8713
1260 BZQ 0.8712
1261 VM1 0.8712
1262 MWJ 0.8712
1263 PGH 0.8712
1264 GNM 0.8711
1265 4P0 0.8710
1266 QMS 0.8710
1267 LKA 0.8709
1268 4NG 0.8708
1269 UNC 0.8708
1270 LQ2 0.8708
1271 6AI 0.8707
1272 L5E 0.8707
1273 4OG 0.8707
1274 5SG 0.8706
1275 948 0.8706
1276 HBI 0.8705
1277 ZZT 0.8705
1278 OXZ 0.8704
1279 YIO 0.8703
1280 B60 0.8703
1281 5TY 0.8703
1282 SJK 0.8702
1283 M6W 0.8702
1284 344 0.8701
1285 3Z7 0.8701
1286 MAH 0.8700
1287 FA6 0.8700
1288 GIF 0.8700
1289 HG3 0.8699
1290 5IQ 0.8699
1291 ADZ 0.8698
1292 KG1 0.8697
1293 JPZ 0.8697
1294 BCK 0.8696
1295 THA 0.8696
1296 4NZ 0.8695
1297 4JJ 0.8694
1298 PE0 0.8694
1299 N2M 0.8694
1300 URF 0.8694
1301 PFB 0.8694
1302 4CL 0.8693
1303 G6P 0.8693
1304 XSP 0.8693
1305 7ZL 0.8693
1306 GBN 0.8693
1307 BHH 0.8692
1308 EWG 0.8692
1309 4YS 0.8692
1310 QUZ 0.8692
1311 DPT 0.8691
1312 BDI 0.8690
1313 KDF 0.8690
1314 G12 0.8688
1315 2CQ 0.8688
1316 EE8 0.8688
1317 XAN 0.8687
1318 DBJ 0.8687
1319 XQG 0.8686
1320 9FH 0.8686
1321 OKG 0.8684
1322 LI6 0.8684
1323 9KT 0.8684
1324 CCU 0.8684
1325 20J 0.8684
1326 MIG 0.8683
1327 N2Y 0.8683
1328 8NY 0.8683
1329 APZ 0.8683
1330 FBF 0.8683
1331 45C 0.8682
1332 5OO 0.8681
1333 AJ2 0.8681
1334 K82 0.8680
1335 MT5 0.8680
1336 2KU 0.8679
1337 78U 0.8678
1338 S7S 0.8678
1339 EV2 0.8677
1340 CWD 0.8677
1341 CR1 0.8677
1342 TR4 0.8677
1343 B5D 0.8677
1344 5JQ 0.8676
1345 Q06 0.8676
1346 ADE 0.8676
1347 657 0.8675
1348 289 0.8675
1349 JYT 0.8674
1350 JR2 0.8674
1351 37T 0.8674
1352 TZE 0.8674
1353 GUN 0.8674
1354 MCT 0.8673
1355 MEW 0.8673
1356 HJP 0.8673
1357 PLU 0.8673
1358 JAH 0.8672
1359 ISA 0.8672
1360 86L 0.8670
1361 4HO 0.8669
1362 AQO 0.8669
1363 H33 0.8668
1364 5Q0 0.8667
1365 3AE 0.8667
1366 X1P 0.8667
1367 FF3 0.8666
1368 7I2 0.8664
1369 JYD 0.8664
1370 8G0 0.8664
1371 LR5 0.8664
1372 G3H 0.8664
1373 W81 0.8664
1374 0RW 0.8663
1375 M5K 0.8661
1376 4FE 0.8660
1377 DMJ 0.8660
1378 Y4L 0.8660
1379 PXM 0.8659
1380 MAN 0.8658
1381 Q04 0.8657
1382 BWD 0.8656
1383 G14 0.8655
1384 1DW 0.8654
1385 IPZ 0.8654
1386 AZ8 0.8652
1387 HQY 0.8652
1388 4A5 0.8651
1389 3RI 0.8651
1390 PLR 0.8651
1391 AC2 0.8651
1392 S7J 0.8650
1393 BGP 0.8650
1394 0OC 0.8649
1395 ZZ3 0.8648
1396 FCD 0.8647
1397 LTN 0.8645
1398 1MC 0.8644
1399 PLP 0.8643
1400 2YU 0.8642
1401 M0Q 0.8642
1402 SC2 0.8642
1403 PFL 0.8642
1404 E3X 0.8641
1405 JZ2 0.8641
1406 KYA 0.8641
1407 K80 0.8641
1408 M3Q 0.8640
1409 TC7 0.8640
1410 S76 0.8639
1411 Z13 0.8639
1412 4XH 0.8638
1413 0QW 0.8637
1414 MRZ 0.8635
1415 2AC 0.8634
1416 MZT 0.8634
1417 23A 0.8634
1418 2GS 0.8634
1419 C0H 0.8631
1420 AVI 0.8631
1421 CRN 0.8631
1422 RP3 0.8630
1423 WBU 0.8630
1424 ABN 0.8629
1425 AZM 0.8629
1426 G3P 0.8628
1427 LDC 0.8627
1428 M6N 0.8627
1429 D2G 0.8627
1430 XBZ 0.8625
1431 HWD 0.8624
1432 K3Q 0.8623
1433 55D 0.8622
1434 TOH 0.8621
1435 YF3 0.8619
1436 SWX 0.8618
1437 FDB 0.8617
1438 A1U 0.8617
1439 0R0 0.8617
1440 6X9 0.8617
1441 R8S 0.8615
1442 IWD 0.8614
1443 DIE 0.8614
1444 JVN 0.8614
1445 4ZE 0.8612
1446 4NS 0.8611
1447 5MH 0.8611
1448 9EW 0.8611
1449 TH0 0.8610
1450 AGK 0.8609
1451 NGA 0.8608
1452 5AD 0.8607
1453 R9G 0.8607
1454 HH8 0.8606
1455 FMQ 0.8604
1456 SVN 0.8603
1457 P3K 0.8601
1458 Q71 0.8601
1459 Y8I 0.8599
1460 MWM 0.8598
1461 7NI 0.8597
1462 46M 0.8595
1463 FLC 0.8595
1464 KYN 0.8592
1465 2A7 0.8590
1466 MES 0.8589
1467 GCW 0.8589
1468 AG2 0.8586
1469 ICP 0.8585
1470 BDF 0.8585
1471 791 0.8584
1472 H5B 0.8583
1473 TDR 0.8581
1474 HT4 0.8580
1475 AA 0.8576
1476 ODK 0.8573
1477 1GP 0.8570
1478 2B4 0.8569
1479 NID 0.8566
1480 ARG 0.8564
1481 LRH 0.8562
1482 51F 0.8557
1483 ANF 0.8557
1484 1PS 0.8555
1485 3MG 0.8555
1486 4ZC 0.8553
1487 0VT 0.8552
1488 RAM 0.8548
1489 GLY PRO 0.8547
1490 PQZ 0.8546
1491 2D2 0.8546
1492 IPD 0.8539
1493 F81 0.8537
1494 5GT 0.8536
1495 HSM 0.8535
1496 PLP PMP 0.8531
1497 1XM 0.8529
1498 MEV 0.8526
1499 92O 0.8524
1500 MHK 0.8523
1501 DCZ 0.8517
1502 PJL 0.8517
1503 GHM 0.8516
1504 Q77 0.8504
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4ANP; Ligand: 3QI; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4anp.bio1) has 31 residues
No: Leader PDB Ligand Sequence Similarity
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