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Receptor
PDB id Resolution Class Description Source Keywords
4P32 1.55 Å EC: 3.6.3.- CRYSTAL STRUCTURE OF E. COLI LPTB IN COMPLEX WITH ADP-MAGNES ESCHERICHIA COLI ABC TRANSPORTER NUCLEOTIDE-BINDING DOMAIN ATPASE ATP BINDHYDROLASE
Ref.: DECOUPLING CATALYTIC ACTIVITY FROM BIOLOGICAL FUNCT THE ATPASE THAT POWERS LIPOPOLYSACCHARIDE TRANSPORT PROC.NATL.ACAD.SCI.USA V. 111 4982 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:402;
B:402;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ADP B:401;
A:401;
Valid;
Valid;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6B8B 1.95 Å EC: 3.6.3.- E. COLI LPTB IN COMPLEX WITH ADP AND A NOVOBIOCIN DERIVATIVE ESCHERICHIA COLI (STRAIN K12) LPTB ABC TRANSPORTER LPS TRANSPORT LIPID TRANSPORT LIPIDTRANSPORT-ACTIVATOR COMPLEX
Ref.: THE ANTIBIOTIC NOVOBIOCIN BINDS AND ACTIVATES THE A THAT POWERS LIPOPOLYSACCHARIDE TRANSPORT. J. AM. CHEM. SOC. V. 139 17221 2017
Members (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4QC2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 4P33 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 4P32 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
4 4P31 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
5 6B89 - NOV C31 H36 N2 O11 Cc1c(ccc2c....
6 6B8B - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4QC2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 4P33 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 4P32 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
4 4P31 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
5 6B89 - NOV C31 H36 N2 O11 Cc1c(ccc2c....
6 6B8B - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4QC2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 4P33 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 4P32 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
4 4P31 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
5 6B89 - NOV C31 H36 N2 O11 Cc1c(ccc2c....
6 6B8B - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6B8B; Ligand: ADP; Similar sites found with APoc: 668
This union binding pocket(no: 1) in the query (biounit: 6b8b.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1M7B GTP None
2 2O66 FLC None
3 4Z7X 3CX None
4 3FKQ ATP 1.60643
5 1Z0K GTP 1.74419
6 3WY9 GDP 2.00803
7 3WYA GDP 2.00803
8 4TL6 ANP 2.00803
9 1WOG 16D 2.00803
10 2CXG GLC GLC 2.00803
11 5LQ8 GB 2.00803
12 5UIV ADP 2.20264
13 4U5X GNP 2.24719
14 2GJ8 ALF GDP 2.32558
15 2DT9 THR 2.39521
16 4YDS ATP 2.40964
17 5HCN GCP 2.40964
18 3RC3 ANP 2.40964
19 3EZ2 ADP 2.40964
20 5HV7 RBL 2.40964
21 5K5Z ANP 2.40964
22 2WOJ ADP ALF 2.40964
23 3ZS9 ADP ALF 2.40964
24 1F5N GNP 2.40964
25 1GWN GTP 2.43902
26 1ION ADP 2.46914
27 2GCO GNP 2.48756
28 2GCN GDP 2.48756
29 1Z83 AP5 2.55102
30 5GVR LMR 2.5641
31 4WOP CTP 2.66667
32 4J0Q GDP 2.77136
33 4DKX GDP 2.77778
34 3TMK T5A 2.77778
35 1GOJ ADP 2.81124
36 3EWA ANP 2.81124
37 1MKY GDP 2.81124
38 3HU3 AGS 2.81124
39 1SVM ATP 2.81124
40 4R43 GDP 2.81124
41 4FCW ADP 2.81124
42 4Q1A 2XZ 2.81124
43 4Q1A UDP 2.81124
44 5Z69 AGS 2.81124
45 4LJ9 ACP 2.81124
46 2QEN ADP 2.81124
47 4RD0 GDP 2.81124
48 5JVB 2PO 2.81124
49 4N4J HG1 2.81124
50 4NCN GTP 2.81124
51 3RAB GNP 2.95858
52 2W58 ADP 2.9703
53 2XTN GTP 2.99145
54 5VGR GDP 3.01624
55 1OE0 TTP 3.04348
56 3IUY AMP 3.07018
57 3PQC GDP 3.07692
58 2CHG ANP 3.09735
59 1DS6 GDP 3.125
60 5F90 LMR 3.20513
61 5F90 GLA GAL 3.20513
62 5F90 GLA GAL BGC 5VQ 3.20513
63 5W7Q GDP 3.21285
64 5ZBR ANP 3.21285
65 1G41 ADP 3.21285
66 1FNN ADP 3.21285
67 2D7D ADP 3.21285
68 2BIF SIN 3.21285
69 2BIF ANP 3.21285
70 2OM2 GDP 3.21285
71 2QZ4 ADP 3.21285
72 5Z20 OXM 3.21285
73 6AU6 GDP 3.21285
74 2WKQ GTP 3.21285
75 1ZCB GDP 3.21285
76 1SVK ALF GDP 3.21285
77 1K6M AGS 3.21285
78 1Y3A GDP 3.21285
79 5O2J 2PO 3.21285
80 4OHY ANP 3.21285
81 1BH2 GSP 3.21285
82 1GXU 2HP 3.2967
83 2Y8E GNP 3.35196
84 3ZQ6 ADP ALF 3.39506
85 1SKQ GDP 3.44828
86 2EW1 GNP 3.48259
87 1YZQ GNP 3.52941
88 2J0W ASP 3.56347
89 1U8Z GDP 3.57143
90 2ZTS ADP 3.58566
91 5XDR ADP 3.61446
92 3A1S GDP 3.61446
93 5FTB ANP 3.61446
94 5H7J GCP 3.61446
95 5FHD ADP ALF 3.61446
96 5JCP GDP ALF 3.61446
97 5AK0 8V1 3.61446
98 6HKE LMR 3.61446
99 5LEF GTP 3.61446
100 1G4U GDP 3.61446
101 1D2E GDP 3.61446
102 6HKE MLT 3.61446
103 3GJ3 GDP 3.61991
104 3GJ4 GDP 3.61991
105 3GJ0 GDP 3.61991
106 3GJ5 GDP 3.61991
107 4DID GDP 3.62694
108 3H86 AP5 3.64583
109 1A4R GDP 3.66492
110 1A4R GNH 3.66492
111 4MKG AP5 3.68664
112 4MKF AP5 3.68664
113 1S3G AP5 3.68664
114 5BXQ GDP 3.7037
115 5KUT GDP 3.7037
116 1D5C GDP 3.7037
117 1IBR GNP 3.7037
118 4LPS GDP 3.71901
119 3BOS CDP 3.71901
120 3FYH ADP 3.72671
121 2IL4 COA 3.8835
122 3IIJ ADP 3.88889
123 1RYH GNP 3.94089
124 4JLS 3ZE 3.94737
125 1F9V ADP 4.01606
126 5CK5 GDP 4.01606
127 1XKV ATP 4.01606
128 4LC1 GDP 4.01606
129 3CNL GNP 4.01606
130 1U0J ADP 4.01606
131 2CE7 ADP 4.01606
132 6G14 G4P 4.01606
133 1WDT GTP 4.01606
134 5MZN ADP 4.01606
135 1OS1 PYR 4.01606
136 1OS1 ATP 4.01606
137 2ZPT A3P 4.01606
138 2FJU GSP 4.01606
139 2XTZ GSP 4.01606
140 3FIU POP 4.01606
141 1IHU AF3 4.01606
142 4PJ3 ANP 4.01606
143 2Q8M AMP 4.01606
144 1IHU ADP 4.01606
145 2B8T THM 4.03587
146 3GJ7 GDP 4.08163
147 1AKY AP5 4.09091
148 5KSP GDP 4.21053
149 1Z06 GNP 4.2328
150 5U32 GDP 4.23729
151 2J0V GDP 4.24528
152 3SBD GNP 4.27807
153 1MH1 GNP 4.30108
154 3PCR GTP 4.32099
155 1YZN GNP 4.32432
156 3RWO GDP 4.32432
157 2JAQ DCP 4.39024
158 4AG5 ADP 4.41767
159 2RCN GDP 4.41767
160 4ZNL BEF ADP 4.41767
161 5WC2 ADP 4.41767
162 5W75 SUC 4.41767
163 5W75 GDP 4.41767
164 5H68 AGS 4.41767
165 1X6V ADP 4.41767
166 2ZPA ADP 4.41767
167 4DDY DN6 4.41767
168 3FWY ADP 4.41767
169 2G77 GDP 4.41767
170 5LLB 6YZ 4.41767
171 2FNA ADP 4.41767
172 5KDO GDP 4.41767
173 1GOT GDP 4.41767
174 4RZ3 ADP 4.41767
175 1WF3 GNP 4.41767
176 1GVF PGH 4.41767
177 1E96 GTP 4.4335
178 5O74 GDP 4.44444
179 2CDN ADP 4.47761
180 5G41 AP5 4.4843
181 2A9K GDP 4.4843
182 6BSX E7S 4.49438
183 6BSX GDP 4.49438
184 1S8F GDP 4.51977
185 2F9L GDP 4.52261
186 1WA5 GTP 4.54545
187 1HE1 AF3 4.54545
188 1HE1 GDP 4.54545
189 3NKV GNP 4.57143
190 4NU0 AP5 4.60829
191 1ZIN AP5 4.60829
192 3BC1 GNP 4.61538
193 3FB4 AP5 4.62963
194 1G3Q ADP 4.64135
195 2PL3 ADP 4.66102
196 4X8O AP5 4.6729
197 1NF3 GNP 4.6875
198 4TMK T5A 4.69484
199 1G16 GDP 4.70588
200 1OIX GDP 4.71204
201 1OIV GDP 4.71204
202 4V0K GDP 4.73373
203 1KAO GDP 4.79042
204 3COB ADP 4.81928
205 5Y6N ADP 4.81928
206 4IEE AGS 4.81928
207 4HSE ADP 4.81928
208 4YJ1 ADP 4.81928
209 5L3V GDP 4.81928
210 3DEF GDP 4.81928
211 4XGU ADP 4.81928
212 2GDJ ANP 4.81928
213 5HPY GDP 4.81928
214 1OW3 GDP 4.81928
215 4ZG4 VO4 ADP 4.81928
216 4ITR GDP 4.81928
217 1DAR GDP 4.81928
218 4FRZ ADP 4.81928
219 5IRR GSP 4.81928
220 4XTR ADP 4.81928
221 4WOH 4NP 4.81928
222 4XTR ATP 4.81928
223 3BER AMP 4.81928
224 2O0J ADP 4.81928
225 4XVU ATP 4.81928
226 2CUN 3PG 4.81928
227 6CS8 F9Y 4.81928
228 1VG0 GDP 4.83092
229 1VG8 GNP 4.83092
230 2RGX AP5 4.85437
231 3LXR GDP 4.86486
232 6BC0 GSP 4.86486
233 6BCB GSP 4.86486
234 6BCA GSP 4.86486
235 5G3Y ADP 4.86726
236 1Y63 ADP 4.8913
237 1KMQ GNP 4.8913
238 3DKP ADP 4.89796
239 1DAK DPU 4.91071
240 1DAK ADP 4.91071
241 1UKZ ADP 4.92611
242 1KY3 GDP 4.94506
243 2CJU PHX 4.95868
244 4XOI GTP 5
245 4HI0 GDP 5.02513
246 5E5U MLI 5.02513
247 4XSH GSP 5.02793
248 5JCZ GDP 5.02793
249 3T1O GDP 5.05051
250 4WEI GLC GAL 5.05415
251 1X1R GDP 5.05618
252 4LX0 BEF GDP 5.08475
253 4BQS K2Q 5.11364
254 4BQS ADP 5.11364
255 2ORV 4TA 5.12821
256 4LHW GNP 5.17241
257 3DOE GTP 5.20833
258 2WIC GNP 5.22088
259 4R98 GNH 5.22088
260 6FAA ADP 5.22088
261 1ZD9 GDP 5.22088
262 1NRJ GTP 5.22088
263 5CIC 51R 5.22088
264 4NON GDP 5.22088
265 3MJH GTP 5.22088
266 5Z21 OXM 5.22088
267 1MO9 KPC 5.22088
268 1MO9 FAD 5.22088
269 2HV8 GTP 5.23256
270 4QRH 0O2 5.2381
271 2YOH WMJ 5.2381
272 4QOS ADP 5.28302
273 2X77 GDP 5.29101
274 5UQW GDP 5.29101
275 1G7C 5GP 5.31915
276 1JJV ATP 5.33981
277 1ZUI SKM 5.35714
278 1Z2A GDP 5.35714
279 2D7C GTP 5.38922
280 3W5J GDP 5.39216
281 1VG1 GDP 5.40541
282 1VG9 GDP 5.40541
283 1GRN AF3 5.41872
284 1GRN GDP 5.41872
285 1LVG ADP 5.55556
286 5ZB0 ADP 5.55556
287 5ZB0 TYD 5.55556
288 5DIF GNP 5.59441
289 5UWI GNP 5.59441
290 5UWU GNP 5.59441
291 5UWQ GNP 5.59441
292 6CIT GNP 5.59441
293 5UWR GNP 5.59441
294 5UWJ GNP 5.59441
295 5UWO GNP 5.59441
296 5UWW GNP 5.59441
297 5UWT GNP 5.59441
298 5DHF GNP 5.59441
299 5UWP GNP 5.59441
300 5UWS GNP 5.59441
301 5DI9 GNP 5.59441
302 6A20 ADP 5.62249
303 5M04 GDP 5.62249
304 1FZQ GDP 5.62249
305 3ZFD ANP 5.62249
306 5N69 ADP 5.62249
307 1SQ5 ADP 5.62249
308 2IS6 ADP 5.62249
309 5IRN ADP 5.62249
310 4DCT GDP 5.62249
311 3TBK ANP 5.62249
312 1Z6T ADP 5.62249
313 3EC1 GDP 5.62249
314 4NE2 SH2 5.62249
315 4NE2 ADP 5.62249
316 4GOJ GNP 5.62249
317 3DZD ADP 5.62249
318 1TQ4 GDP 5.62249
319 3KJI ADP 5.62249
320 2C9O ADP 5.62249
321 4KVA GTP 5.62249
322 1NY5 ADP 5.62249
323 2JK0 ASP 5.62249
324 3WXM GTP 5.62249
325 3VMF GTP 5.62249
326 5MUL BDP 5.62249
327 2W2X GSP 5.64516
328 5Z2M GTP 5.68182
329 4HAT GNP 5.71429
330 2VOH CIT 5.73248
331 4KBF AMP 5.75342
332 1XX6 ADP 5.75916
333 1TU3 GNP 5.84795
334 2WJG GDP 5.85106
335 1R2Q GNP 5.88235
336 3AQ4 GDP 5.97826
337 4UXH T5A 5.97826
338 3UIE ANP 6
339 5FG3 GDP 6.0241
340 5YT0 GDP 6.0241
341 2DPY ADP 6.0241
342 2IYL GDP 6.0241
343 4PX9 ADP 6.0241
344 2OBM ADP 6.0241
345 5I0H ADP BEF 6.0241
346 1E2K TMC 6.0241
347 5DI3 GNP 6.0241
348 4BFW ZVW 6.0241
349 1YTM ATP 6.0241
350 3P4X ADP 6.0241
351 5H4S RAM 6.0241
352 1OYY AGS 6.0241
353 4YC7 GNP 6.0241
354 3KC1 2T6 6.0241
355 1Q19 SSC 6.0241
356 2W83 GTP 6.06061
357 1MR3 G3D 6.07735
358 1W4R TTP 6.15385
359 3N5C GDP 6.17284
360 2HF9 GSP 6.19469
361 2CJW GDP 6.25
362 1HTW ADP 6.32911
363 4PPF FLC 6.4257
364 3DC4 ADP 6.4257
365 5LB3 ADP 6.4257
366 2A5J GDP 6.4257
367 2EFE GNH 6.4257
368 4V03 ADP 6.4257
369 1P72 ADP 6.4257
370 2FAH GDP 6.4257
371 4H1V GNP 6.4257
372 1H65 GDP 6.4257
373 5IRC GDP 6.46766
374 1Z0J GTP 6.47059
375 1YVD GNP 6.50888
376 4TTQ ATP 6.51163
377 5EXT ADP 6.53846
378 1BO4 COA 6.54762
379 4KVG GTP 6.54762
380 4HDO GNP 6.58683
381 3X1Z GNP 6.58683
382 4HDQ GNP 6.58683
383 4M9Q GNP 6.60793
384 2WJH GDP 6.62651
385 2WJH FLC 6.62651
386 1SVI GDP 6.66667
387 2F3R G5P 6.76329
388 1FQK GDP 6.80272
389 1FQJ GDP 6.80272
390 4B47 GDP 6.82731
391 1Z0A GDP 6.82731
392 1UPT GTP 6.82731
393 2V7Q ADP 6.82731
394 1W0J ADP 6.82731
395 2CK3 ANP 6.82731
396 1CR1 TTP 6.82731
397 6B4K ANP 6.82731
398 6H5E ANP 6.82731
399 2BCG GDP 6.82731
400 2CK3 ADP 6.82731
401 3Q9L ATP 6.82731
402 1W0J ADP BEF 6.82731
403 2V7Q ATP 6.82731
404 1R4A GNP 6.82731
405 1UJ2 C5P 6.82731
406 2FH5 GTP 6.82731
407 4Y4V DAL 6.82731
408 1G7S GDP 6.82731
409 3CPJ GDP 6.82731
410 3QVV A3P 6.82731
411 3QVV 3QV 6.82731
412 2F5X ASP 6.82731
413 1UJ2 ADP 6.82731
414 5OCG GNP 6.87831
415 2HT6 GDP 6.89655
416 3AB3 GDP 6.91057
417 2C5L GTP 6.93642
418 6FA4 GNP 6.93642
419 1NN5 ANP 6.97674
420 1NN5 2DT 6.97674
421 4K81 GTP 7.01754
422 5O2T GSP 7.10059
423 5E95 GDP 7.14286
424 3LRE ADP 7.22892
425 3A4M ADP 7.22892
426 1V8K ANP 7.22892
427 5W76 GDP 7.22892
428 1CLU DBG 7.22892
429 5M7P ADP 7.22892
430 1WQ1 AF3 7.22892
431 5XKT GNP 7.22892
432 3DDC GNP 7.22892
433 1WQ1 GDP 7.22892
434 4CVN ADP 7.29927
435 3WYF GTP 7.30594
436 3M1I GTP 7.30594
437 5XC5 GTP 7.38636
438 2QN6 GDP 7.52688
439 2B4B COA 7.60234
440 2B4D COA 7.60234
441 3GJ8 GDP 7.6087
442 2QQ0 ANP 7.6087
443 2QQ0 THM 7.6087
444 2QQ0 TMP 7.6087
445 2QQ0 ADP 7.6087
446 2OG2 MLI 7.63052
447 1KK1 GNP 7.63052
448 1R6B ADP 7.63052
449 4E03 ADP 7.63052
450 5IFS ADP 7.63052
451 1NJF ADP 7.63052
452 1NJF AGS 7.63052
453 3R7F CP 7.63052
454 3SFV GDP 7.63052
455 1VHT BA3 7.63052
456 3E70 GDP 7.63052
457 3TNF GNP 7.63052
458 2VTD LKM 7.63052
459 2ODE ALF GDP 7.63052
460 3TKL GTP 7.63052
461 3CH5 GDP 7.69231
462 2OFW ADX 7.69231
463 1QF9 ADP 7.73196
464 1QF9 ALF 7.73196
465 1QF9 C5P 7.73196
466 1Z0F GDP 7.82123
467 1G8S MET 7.82609
468 5J1S ATP 7.94979
469 1M7G AV2 8.03213
470 5LTJ ADP 8.03213
471 5LTJ BEF 8.03213
472 4D0N GDP 8.03213
473 4IHQ ADP 8.03213
474 3T5G GDP 8.03213
475 5TB5 GDP 8.03213
476 3QKT ANP 8.03213
477 5TAR GDP 8.03213
478 2Q2Y ADP 8.03213
479 2Q2Y MKR 8.03213
480 5VHC BEF ADP 8.03213
481 4A4Z ANP 8.03213
482 1KSH GDP 8.03213
483 1M7G ADP 8.03213
484 1M7G ADX 8.03213
485 5HR5 ADP 8.03213
486 5J1J ANP 8.03213
487 2BME GNP 8.06452
488 2FFQ GSP 8.18713
489 5WDR GNP 8.18713
490 4ZI2 GNP 8.27068
491 2QTV GNP 8.38323
492 4C4P GNP 8.41121
493 5TSH ADP 8.43373
494 5TSH ANP 8.43373
495 1G6O ADP 8.43373
496 2WMO GTP 8.43373
497 5KSZ GCP 8.43373
498 2C77 GNP 8.43373
499 4P4T GDP 8.43373
500 2ZEJ GDP 8.43373
501 2C78 GNP 8.43373
502 2NGR AF3 8.54701
503 2NGR GDP 8.54701
504 4D0G GTP 8.69565
505 4QM7 GTP 8.77193
506 2A5F GTP 8.80829
507 3B9Q MLI 8.83534
508 2ZFI ADP 8.83534
509 5BN3 ADP 8.83534
510 3TK1 GDP 8.83534
511 5L3R GCP 8.83534
512 6DEF GCP 8.83534
513 3CX8 GSP 8.86699
514 1I4D GDP 8.92857
515 2PEZ GGZ 8.93855
516 2PEZ DAT 8.93855
517 1UAD GNP 9.09091
518 1X8J A3P 9.11681
519 1BG2 ADP 9.23695
520 4KFU ACP 9.23695
521 3U6B GDP 9.23695
522 4P3Y GDP 9.23695
523 1D8T GDP 9.23695
524 4G5G GDP 9.23695
525 5JBQ GDP 9.23695
526 3U6K GDP 9.23695
527 4PC3 GDP 9.23695
528 2BVN GNP 9.23695
529 3IO3 ADP 9.23695
530 2FSH ANP 9.23695
531 3REF GDP 9.27835
532 1CXZ GSP 9.30233
533 2I6U CP 9.44625
534 4R2I ANP 9.52381
535 2Y65 ADP 9.63855
536 2GKS ADP 9.63855
537 1XMV ADP 9.63855
538 3BFV ADP 9.63855
539 5H7K GDP 9.63855
540 6C90 ADP 9.63855
541 3GJX GTP 9.63855
542 3QDK QDK 9.63855
543 2BEK ATP 9.63855
544 1CS4 GSP 9.77778
545 3QF7 ANP 10
546 3QBT GNP 10
547 1RRC ADP 10.0402
548 3MD0 GDP 10.0402
549 5L3W GDP 10.0402
550 1W5T ANP 10.0402
551 5L3S G 10.0402
552 2OZE AGS 10.0402
553 5L3S GNP 10.0402
554 6D5M GNP 10.0402
555 6D55 GNP 10.0402
556 6D5L GNP 10.0402
557 6D5G GNP 10.0402
558 6D5J GNP 10.0402
559 6D56 GNP 10.0402
560 6D59 GNP 10.0402
561 6BVJ GNP 10.0402
562 6D5E GNP 10.0402
563 6BVK GNP 10.0402
564 6D5V GNP 10.0402
565 6BVM GNP 10.0402
566 6BVL GNP 10.0402
567 6BVI GNP 10.0402
568 6D5H GNP 10.0402
569 1NVV GNP 10.0402
570 1W5T ADP 10.0402
571 5BQ5 ADP BEF 10.0529
572 5UPK GNP 10.4167
573 3B7G ANP 10.4348
574 3KTA AP5 10.4396
575 2VVG ADP 10.4418
576 2ZR9 DTP 10.4418
577 3Q85 GNP 10.4418
578 4LYA ATP 10.4418
579 1IN4 ADP 10.4418
580 4OI4 ATP 10.4418
581 3VX3 ADP 10.4839
582 1F6B GDP 10.6061
583 5EE5 GTP 10.7981
584 2KIN ADP 10.8434
585 1T5C ADP 10.8434
586 1YRB GDP 10.8434
587 1LVK MNT BEF 10.8434
588 1KO8 6PG 10.8571
589 4BAS GNP 11.0553
590 3H4S ADP 11.1111
591 5SZH GNP 11.1111
592 4JLV ADP 11.245
593 5YLF BGC 11.245
594 2JLR ANP 11.245
595 1XP8 AGS 11.245
596 2VB6 ADP BEF 11.245
597 1W7J ADP BEF 11.245
598 4PFO ADP 11.245
599 5LV1 78T 11.245
600 2WHX ADP 12.0482
601 1VKJ A3P 12.0482
602 2J5V PCA 12.4498
603 3T12 GDP ALF 12.5
604 1LFD GNP 12.6437
605 3ZIA ADP 12.6984
606 3ZIA ATP 12.6984
607 2XAU ADP 12.8514
608 1FP6 ADP 12.8514
609 4WZA ACP 12.8514
610 4WZA ADP 12.8514
611 1OFH ADP 12.8514
612 2XT3 ADP 13.253
613 2UZI GTP 13.4615
614 2HCJ GDP 13.5135
615 1F2U ATP 13.5135
616 1RJ9 GCP 13.6546
617 4ZKD GDP 14.0562
618 3AB4 THR 14.0562
619 2DTJ THR 14.0562
620 5H67 ATP 14.3617
621 5OEC GDP 14.7541
622 5GOE GDP 14.8594
623 2NCD ADP 15.261
624 1EK0 GNP 15.2941
625 1ZJ6 G3D 16.4659
626 1ZC3 GNP 16.8142
627 3Q72 GNP 16.8675
628 6CRK GDP 16.9014
629 1GP2 GDP 16.9014
630 1RE0 GDP 17.2691
631 1S9D GDP 17.2691
632 1XEX ATP 17.4419
633 1XPJ TLA 18.254
634 2X7I CIT 18.5065
635 3WYG GTP 18.6813
636 4YLG GDP 18.8755
637 1PUJ GNP 18.8755
638 5MVR ADP 19.1358
639 1M2O GNP 20.8835
640 4KAX GTP 21.7391
641 4D81 ADP 22.8916
642 1B7T ADP 23.0769
643 3N9R TD3 23.2932
644 1KK8 BEF ADP 23.3766
645 1YZG GDP 23.4637
646 1O3Y GTP 25.9036
647 1J2J GTP 25.9036
648 2J59 GTP 25.9036
649 5WLB GNP 26.4706
650 3KUD GDP 28.3951
651 1GUA GNP 28.3951
652 2CBZ ATP 30.8017
653 5YV5 ADP 31.3253
654 2GK6 ADP 31.3253
655 5ZXD ATP 32.9317
656 3NHB ADP 34.5382
657 1YQT ADP 34.9398
658 1R0X ATP 40.9639
659 4WZ6 ATP 41.3655
660 1JJ7 ADP 42.9719
661 2PZE ATP 44.9782
662 2IXE ATP 45.3815
663 1L2T ATP 46.383
664 5X40 ACP 46.5863
665 4U00 ADP 47.7912
666 2AWN ADP 48.996
667 3RLF ANP 48.996
668 2D2F ADP 49.7992
669 5UWH GNP 50
Pocket No.: 2; Query (leader) PDB : 6B8B; Ligand: CZJ; Similar sites found with APoc: 10
This union binding pocket(no: 2) in the query (biounit: 6b8b.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 3W9F I3P 2.00803
2 2QFY AKG 2.81124
3 1HEX NAD 3.21285
4 4G86 BNT 4.01606
5 4FC7 COA 4.01606
6 4FC7 NAP 4.01606
7 4DDY DN6 4.41767
8 1M4I PAP 6.07735
9 1M4I KAN 6.07735
10 1M4I COA 6.07735
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