Receptor
PDB id Resolution Class Description Source Keywords
4OTI 1.93 Å EC: 2.7.11.13 CRYSTAL STRUCTURE OF PRK1 CATALYTIC DOMAIN IN COMPLEX WITH T HOMO SAPIENS PRK1 PKN1 PROTEIN KINASE C RELATED KINASE 1 KINASE PROTEKINASE ATP BINDING PHOSPHORYLATION TRANSFERASE-TRANSFERAINHIBITOR COMPLEX
Ref.: CRYSTAL STRUCTURES OF PRK1 IN COMPLEX WITH THE CLIN COMPOUNDS LESTAURTINIB AND TOFACITINIB REVEAL LIGAN CONFORMATIONAL CHANGES. PLOS ONE V. 9 03638 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MI1 A:1001;
Valid;
none;
ic50 = 43 nM
312.37 C16 H20 N6 O C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4OTH 1.8 Å EC: 2.7.11.13 CRYSTAL STRUCTURE OF PRK1 CATALYTIC DOMAIN IN COMPLEX WITH R HOMO SAPIENS PRK1 PKN1 PROTEIN KINASE C RELATED KINASE 1 KINASE PROTEKINASE ATP BINDING PHOSPHORYLATION TRANSFERASE-TRANSFERAINHIBITOR COMPLEX
Ref.: CRYSTAL STRUCTURES OF PRK1 IN COMPLEX WITH THE CLIN COMPOUNDS LESTAURTINIB AND TOFACITINIB REVEAL LIGAN CONFORMATIONAL CHANGES. PLOS ONE V. 9 03638 2014
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4OTH ic50 = 9 nM DRN C25 H23 N5 O2 S [H]/N=C(/N....
2 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4OTH ic50 = 9 nM DRN C25 H23 N5 O2 S [H]/N=C(/N....
2 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
50% Homology Family (492)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 2E9O ic50 = 20 nM A58 C25 H27 N3 O2 CC1CCC(CC1....
2 2WMQ - ZYQ C9 H11 N3 O2 S CC(=O)Nc1n....
3 2BRO ic50 = 1.4 uM DF2 C21 H20 N4 O2 c1ccc(cc1)....
4 2QHN ic50 = 980 nM 582 C13 H13 N3 O CCN1c2cccc....
5 4RVM ic50 = 1 nM 3X7 C23 H21 N5 c1cc(ccc1C....
6 5DLS ic50 = 4.4 nM 5CV C31 H34 N6 O3 CC(C)(CN(C....
7 3TKI ic50 = 0.05 nM S25 C20 H23 N7 O2 S c1cnc(cc1N....
8 2YM5 ic50 = 0.43 uM YM5 C18 H21 N5 O2 c1cc(cc(c1....
9 4HYH ic50 = 1 nM 1AM C22 H22 N6 O3 S COc1ccc2c(....
10 1NVS Ki = 15 nM UCM C24 H15 N3 O3 c1ccc2c(c1....
11 2YDK ic50 = 0.007 uM YDK C17 H20 N4 O2 S c1ccc(cc1)....
12 3OT3 ic50 = 0.005 uM 22K C16 H20 Br N7 Cn1cc(cn1)....
13 2HXQ ic50 = 144 nM 373 C24 H26 N4 O c1ccc2c(c1....
14 2QHM ic50 = 660 nM 7CS C16 H19 N3 O2 CN1[C@H]2C....
15 2BRH ic50 = 22 uM DFW C20 H15 N3 O3 c1ccc(cc1)....
16 2R0U ic50 = 1 nM M54 C25 H22 N4 O2 c1cc(cc(c1....
17 1NVR Ki = 7.8 nM STU C28 H26 N4 O3 C[C@@]12[C....
18 3OT8 ic50 = 0.009 uM MI5 C19 H22 N8 S Cc1cc(sn1)....
19 2YM4 ic50 = 1.5 uM 4YM C21 H22 N6 O3 CCOC(=O)c1....
20 4HYI ic50 = 2 nM 1AO C21 H20 N6 O S c1ccc2c(c1....
21 4RVL ic50 = 41.7 nM 3XL C17 H10 N4 O c1ccc(c(c1....
22 2XF0 ic50 = 30 uM 4UB C15 H11 N5 c1ccc(cc1)....
23 2YM6 ic50 = 0.88 uM YM6 C14 H16 N6 O c1cncc2c1c....
24 4QYG ic50 = 0.0041 uM 3DW C22 H21 N5 O2 CN1CCN(CC1....
25 3TKH ic50 = 47 nM 07S C23 H27 N7 O2 S c1cc(cnc1)....
26 2XEZ ic50 = 1.5 uM XEZ C12 H9 N7 c1c[nH]nc1....
27 2HXL ic50 = 12 nM 422 C23 H24 N6 c1cc2c(cc1....
28 5F4N ic50 = 2.2 nM 5UY C17 H19 N7 O3 COC(=O)c1c....
29 2C3J Ki = 0.659 uM DBQ C11 H11 N5 O2 c1c[nH]c2c....
30 2YM7 ic50 = 0.13 uM YM7 C15 H18 N8 c1c(ncnc1N....
31 2X8I ic50 = 0.19 uM X8I C17 H13 N3 O2 CC1=CC2=NN....
32 2YDJ ic50 = 0.005 uM YDJ C17 H19 F N4 O2 S c1cc(cc(c1....
33 4QYE ic50 = 1.2 uM 3DL C17 H12 N2 O3 c1cc(cc(c1....
34 2BRG ic50 = 6.1 uM DFY C21 H19 N3 O2 CN(CCO)c1c....
35 2CGU ic50 = 13.4 uM 3A3 C17 H13 N O7 c1cc-2c(cc....
36 2WMR ic50 = 52 uM ZYR C10 H10 N2 O S C1CCc2c(c3....
37 3PA5 ic50 = 2 nM C73 C17 H19 Cl N4 O2 S c1cc(ccc1c....
38 2WMV ic50 = 9.2 uM ZYV C10 H14 N6 O c1[nH]c2c(....
39 2CGX ic50 = 15.6 uM 3D3 C7 H8 N6 O S c1nc(c2c(n....
40 4QYF - 3DV C17 H13 N3 O3 c1cc(cc(c1....
41 3JVS Ki = 0.146 uM AGY C22 H22 N4 O4 CC(C)(C)c1....
42 2WMW ic50 = 0.39 uM ZYW C11 H14 Br N5 O c1c2c(c(cn....
43 2BR1 Ki = 7.2 uM PFP C22 H21 N3 O4 COc1ccc(cc....
44 2C3L Ki = 0.026 uM IDZ C14 H10 N4 c1ccc2c(c1....
45 2X8E ic50 = 0.014 uM X8E C16 H12 N4 O CC1=CC2=NN....
46 2X8D ic50 = 0.8 uM X8D C11 H9 N3 O CC1=CC2=NN....
47 2YEX ic50 = 0.0001 uM YEX C15 H12 N4 O CC1=CC2=NN....
48 2BRM Ki = 1.3 uM DFZ C20 H18 N4 O c1ccc(cc1)....
49 1NVQ Ki = 5.6 nM UCN C28 H26 N4 O4 C[C@@]12[C....
50 3PA4 ic50 = 3 nM C72 C19 H19 Cl N4 O S c1cc(ccc1c....
51 1JSV - U55 C10 H11 N5 O2 S c1cc(ccc1N....
52 1OIQ ic50 = 2.9 uM HDU C14 H13 N5 O Cc1c(n2ccc....
53 2W17 ic50 = 0.002 uM I19 C24 H30 F N7 O Cc1ncc(n1C....
54 2VTP ic50 = 0.003 uM LZ9 C17 H11 F3 N4 O2 c1cc(c(c(c....
55 1JVP ic50 = 1.6 uM LIG C15 H11 N3 c1ccc-2c(c....
56 1FVT - 106 C14 H9 Br N4 O3 S c1cc(ccc1/....
57 4KD1 - 1QK C21 H29 N6 O2 CCc1cnn2c1....
58 3LE6 ic50 = 0.035 uM 2BZ C17 H10 Cl N5 O2 Cc1c-2nc(c....
59 2VTI ic50 = 0.66 uM LZ3 C14 H12 N4 O3 S c1ccc2c(c1....
60 3LFS Ki = 2.5 uM A07 C17 H16 Cl N3 O CCCC(=O)Nc....
61 1PXI - CK1 C8 H5 Cl2 N3 S c1cnc(nc1c....
62 4LYN - 1YG C20 H23 N3 O2 S2 C[C@@H](c1....
63 1YKR ic50 = 0.56 uM 628 C20 H14 Cl2 N4 O3 S c1cc(c(c(c....
64 1PXN Ki ~ 0.32 uM CK6 C15 H15 N5 O S Cc1c(sc(n1....
65 2R3J ic50 = 10 nM SCJ C18 H14 Br N5 c1ccc(cc1)....
66 3IG7 ic50 = 9 nM EFP C18 H22 N4 O3 CC(=O)NC1C....
67 2VTS ic50 = 0.03 uM LZC C16 H23 N7 CC(C)Nc1cc....
68 1P2A ic50 = 12 nM 5BN C17 H15 F N4 O c1cc([nH]c....
69 2BHE ic50 = 1 uM BRY C16 H9 Br N2 O2 c1ccc2c(c1....
70 3UNK ic50 = 15 uM 0BY C17 H13 Cl N4 O2 c1ccc(c(c1....
71 2VTQ ic50 = 0.14 uM LZA C16 H17 F2 N5 O2 c1cc(c(c(c....
72 2C68 ic50 = 1.8 uM CT6 C18 H15 Br N5 c1cc(cc(c1....
73 3TIZ - 3TI C17 H13 N O2 c1ccc2c(c1....
74 3PXY ic50 = 5.9 uM JWS C10 H11 N5 O2 COc1ccc(c(....
75 2R3M ic50 = 10 nM SCX C19 H17 F2 N7 CCc1cnn2c1....
76 5JQ5 Kd = 2341 nM I74 C22 H30 N6 O CC(C)c1cnn....
77 2C6O - 4SP C18 H22 N6 O3 S c1cc(ccc1N....
78 1V1K Ki = 35 uM 3FP C22 H23 F4 N5 O2 CN(C)C[C@H....
79 2VTJ ic50 = 1.9 uM LZ4 C10 H9 Cl N4 O2 S c1cc(ccc1N....
80 3EZV - EZV C25 H25 N7 CN1CCN(CC1....
81 3PXZ Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
82 1W0X - OLO C15 H18 N6 O Cn1cnc2c1n....
83 2XMY Ki = 0.11 nM CDK C18 H21 N5 O4 S2 CC1=C(SC(=....
84 2UZO ic50 = 18 uM C62 C14 H10 N2 O5 S2 c1cc(ccc1c....
85 1KE7 ic50 = 8.9 nM LS3 C20 H15 N3 O4 S c1cc2c(cc1....
86 1DM2 - HMD C11 H10 Br N5 O2 C1CNC(=O)C....
87 1DI8 ic50 = 1 uM DTQ C16 H15 N3 O3 COc1cc2c(c....
88 5JQ8 - I73 C22 H30 N6 O CC(C)c1cnn....
89 1GIJ - 2PU C19 H22 N6 O2 c1cc2c(c(c....
90 2R3P ic50 = 900 nM 3SC C19 H12 Cl2 N6 S c1cc(c(c(c....
91 1KE8 ic50 = 1000 nM LS4 C18 H14 N4 O3 S2 c1ccc2c(c1....
92 2C6I ic50 = 11 uM DT1 C18 H22 N6 O3 S c1cc(ccc1N....
93 1PXP Ki ~ 0.22 uM CK8 C17 H19 N5 S Cc1c(sc(n1....
94 2UZN ic50 = 0.03 uM C96 C15 H13 N3 O4 S2 [H]/N=C/1N....
95 2B55 ic50 = 96 nM D31 C24 H31 N5 O2 c1cc-2c(c(....
96 5K4J - 6QB C21 H18 Cl F N6 O2 Cn1c(ccn1)....
97 3PJ8 - 404 C19 H26 N6 O CC[C@H](CO....
98 3LFQ - A28 C17 H15 F2 N3 O CCCC(=O)Nc....
99 2W05 ic50 = 0.001 uM FRT C20 H26 N6 O3 S Cc1ncc(n1C....
100 2XNB Ki = 149 nM Y8L C19 H22 N6 O S CC1=C(SC(=....
101 1HCK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
102 5IEX - 6AF C17 H21 Br N4 O3 S C[C@H]([C@....
103 2R3H ic50 = 20000 nM SCE C13 H13 N5 Cc1cnc2n1c....
104 3LFN Ki = 3160 nM A27 C23 H21 N3 O2 CCCC(=O)Nc....
105 3PY1 Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
106 2A4L ic50 = 0.4 uM RRC C19 H26 N6 O CC[C@H](CO....
107 1Y8Y ic50 = 2 uM CT7 C13 H11 Cl N4 O2 S CS(=O)(=O)....
108 1OIR ic50 = 0.032 uM HDY C23 H26 N6 O2 Cc1c(n2ccc....
109 1PXJ - CK2 C9 H10 N4 S Cc1c(sc(n1....
110 2VTO ic50 = 0.14 uM LZ8 C17 H13 F N4 O2 c1ccc(cc1)....
111 2BTR ic50 = 95 nM U73 C13 H15 N3 O S CC(C)C1=CN....
112 2VTA ic50 = 185 uM LZ1 C7 H6 N2 c1ccc2c(c1....
113 3EZR - EZR C26 H27 N7 O CN1CCN(CC1....
114 3ULI ic50 = 0.07 uM 1N3 C21 H25 Br N6 O2 COc1ccc(cc....
115 2DS1 ic50 = 6.4 nM 1CD C22 H21 N5 O3 C[C@@H]1C[....
116 5FP5 - 1Y6 C7 H5 F O2 c1cc(ccc1C....
117 2VTH ic50 = 120 uM LZ2 C10 H9 N O3 S c1cc2c(ccc....
118 1KE5 ic50 = 560 nM LS1 C16 H15 N3 O3 S CNS(=O)(=O....
119 3FZ1 - B98 C13 H15 N3 O2 S COc1ccc2c(....
120 1WCC ic50 = 350 uM CIG C4 H4 Cl N3 c1c(nc(cn1....
121 1E1V Ki = 12 uM CMG C12 H17 N5 O c1[nH]c2c(....
122 2VV9 ic50 = 0.017 uM IM9 C23 H29 N7 O2 Cc1ncc(n1C....
123 5IEV - R0N C18 H23 F3 N4 O3 S C[C@H]([C@....
124 4D1X - ESJ C11 H8 N2 O3 S2 c1cc2c(cc1....
125 2BTS ic50 = 20 nM U32 C12 H15 N3 O2 S2 CC(C)c1cnc....
126 1URW ic50 < 0.003 uM I1P C21 H24 N8 O2 S CN(C)CCCNS....
127 5FP6 - MFZ C11 H7 Cl2 N O c1cc(c2c(c....
128 1CKP - PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
129 1KE6 ic50 = 5.7 nM LS2 C17 H15 N5 O3 S2 CNS(=O)(=O....
130 2C6K ic50 = 0.73 uM DT2 C17 H21 N7 O2 S c1cc(ccc1N....
131 2R3Q - 5SC C19 H16 Br N5 O Cc1ccccc1c....
132 1OIT ic50 < 0.003 uM HDT C17 H14 N6 O2 S c1ccn2c(c1....
133 3NS9 ic50 = 0.003 uM NS9 C20 H27 N5 O3 CC(C)c1cnn....
134 1H01 ic50 = 22 uM FAL C21 H23 Cl2 N5 O2 CN(C)C[C@H....
135 2EXM - ZIP C10 H13 N5 CC(=CCNc1c....
136 4BGH ic50 = 4 nM 3I6 C13 H16 Br N5 O3 S C[C@H](CO)....
137 2R3F ic50 = 500 nM SC8 C18 H13 Cl2 N5 c1cc(c(c(c....
138 1GII - 1PU C17 H16 N4 O2 c1ccnc(c1)....
139 2R64 ic50 = 0.03 uM 740 C23 H27 N5 O3 S c1cc(ccc1C....
140 5A14 - LQ5 C24 H26 F3 N7 O2 CN1CCN(CC1....
141 2C6L ic50 = 0.27 uM DT4 C17 H22 N8 O2 S c1cc(ccc1N....
142 2W06 - FRV C18 H20 N6 O2 S Cc1ncc(n1C....
143 4EZ7 - STU C28 H26 N4 O3 C[C@@]12[C....
144 5D1J ic50 = 48 nM 56H C17 H24 N4 O2 S2 CC(C)(C)c1....
145 5IEY - 6AE C14 H19 N5 O3 S C[C@H]([C@....
146 2VTT ic50 = 0.044 uM LZD C16 H17 F2 N5 O2 c1cc(c(c(c....
147 2VU3 ic50 = 0.047 uM LZE C16 H17 Cl2 N5 O2 c1cc(c(c(c....
148 2B54 - D05 C20 H15 Cl3 N4 O3 CCc1c2c(n(....
149 1GZ8 - MBP C10 H13 N5 O2 CC(C)C(=O)....
150 3PY0 ic50 = 0.13 uM SU9 C13 H11 N3 O2 COc1ccc2c(....
151 2VTR ic50 = 1.5 uM LZB C10 H10 Cl N5 CC(C)Nc1cc....
152 1E1X Ki = 1.3 uM NW1 C11 H17 N5 O2 C1CCC(CC1)....
153 3UNJ ic50 = 11 uM 0BX C17 H14 N4 O2 c1ccc(cc1)....
154 2A0C - CK9 C19 H26 N6 O2 CC[C@H](CO....
155 3TIY - TIY C11 H8 O5 c1c2c(c(c(....
156 2R3I ic50 = 1000 nM SCF C18 H14 F N5 c1ccc(c(c1....
157 1VYZ ic50 = 290 nM N5B C13 H13 N3 O c1ccc(cc1)....
158 3WBL ic50 = 23 uM PDY C20 H26 N6 O CCOc1ccc(c....
159 4RJ3 ic50 = 93 nM 3QS C22 H28 N6 O COC1CCN(CC....
160 2VTN ic50 = 0.85 uM LZ7 C12 H11 F N4 O2 CC(=O)Nc1c....
161 1AQ1 - STU C28 H26 N4 O3 C[C@@]12[C....
162 2C6M ic50 = 0.35 uM DT5 C17 H20 N6 O3 S c1cc(ccc1N....
163 2R3L ic50 = 100 nM SCW C18 H14 Br N5 c1ccc(cc1)....
164 1H08 - BYP BWP n/a n/a
165 1B38 Kd = 0.254 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
166 2B52 ic50 = 8 nM D42 C21 H23 N7 O2 S Cc1c(sc(n1....
167 1PXL - CK4 C16 H13 F3 N4 S Cc1c(sc(n1....
168 3S2P ic50 = 0.068 uM PMU C17 H22 N4 O3 CC(C)c1cc(....
169 2R3O ic50 = 600 nM 2SC C19 H17 N5 O c1ccc(cc1)....
170 3IGG ic50 = 95 nM EFQ C16 H19 N3 O3 COc1ccc(cc....
171 1R78 ic50 = 3 nM FMD C20 H20 F N3 O4 C[C@H]([C@....
172 2FVD Ki = 0.003 uM LIA C18 H21 F2 N5 O4 S COc1ccc(c(....
173 2VTL ic50 = 97 uM LZ5 C10 H9 N3 O c1ccc(cc1)....
174 1KE9 ic50 = 660 nM LS5 C16 H15 N5 O3 S c1ccc2c(c1....
175 1PYE ic50 = 0.32 uM PM1 C21 H13 F2 N3 O2 c1ccc(cc1)....
176 4EZ3 - 0S0 C11 H10 N4 O4 S c1cc(ccc1/....
177 1H07 ic50 = 3 uM MFP C24 H27 Br N6 O2 Cc1ccc(c(c....
178 2B53 ic50 = 0.6 uM D23 C19 H19 F3 N4 CC(C)(C)Nc....
179 2DUV ic50 = 0.087 uM 371 C19 H17 N O7 S Cc1cc2c(c(....
180 4D1Z - WG8 C13 H10 N2 O3 S c1cc2ccc(n....
181 4ACM Ki = 210 nM 7YG C20 H23 N7 O3 S CN(C)CCNS(....
182 5LI9 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
183 3A8W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
184 3MB6 ic50 = 100 nM 01I C16 H8 O6 c1cc2c(cc(....
185 5M4F - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
186 5CVH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
187 3BQC ic50 ~ 2 uM EMO C15 H10 O5 Cc1cc2c(c(....
188 5CU2 - 54G C8 H8 O3 Cc1ccc(c(c....
189 5MO5 - 4IH C17 H21 Cl N2 O2 S CS(=O)(=O)....
190 5M4I - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
191 5MP8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
192 5MOV - HC4 C9 H8 O3 c1cc(ccc1C....
193 5MOH - YTX C9 H10 O4 COc1cc(ccc....
194 5CSH Kd = 270 uM 54E C13 H12 Cl N c1ccc(cc1)....
195 3OWL ic50 = 0.67 uM 19E C16 H11 Cl N2 O Cc1cnc(c2c....
196 5H8G ic50 < 0.003 uM 5Y4 C23 H29 N9 O CC(=O)Nc1c....
197 5B0X ic50 = 0.02 uM HCK C18 H14 N2 O4 S COc1ccc(cc....
198 5MO8 Kd = 1.64 uM C98 C26 H26 Cl N3 O4 c1ccc(cc1)....
199 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
200 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
201 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
202 5H8E ic50 < 0.003 uM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
203 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
204 5MOE Kd = 500 uM OQC C11 H10 Cl N O c1cc(c(cc1....
205 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
206 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
207 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
208 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
209 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
210 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
211 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
212 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
213 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
214 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
215 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
216 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
217 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
218 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
219 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
220 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
221 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
222 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
223 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
224 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
225 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
226 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
227 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
228 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
229 3PE1 Ki = 0.38 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
230 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
231 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
232 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
233 2ZJW ic50 = 0.04 uM REF C14 H6 O8 c1c2c-3c(c....
234 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
235 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
236 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
237 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
238 3FHR - P4O C21 H16 N4 O c1ccc2c(c1....
239 3R1N - 05B C22 H21 N5 O3 c1cc2c(cc1....
240 3SHE - I85 C24 H22 F3 N5 O2 c1cc(cc(c1....
241 3BWJ ic50 = 2.6 uM ARX C28 H47 N15 O7 [H]/N=C(N)....
242 3AGL Ki = 16 nM A03 C37 H63 N17 O9 [H]/N=C(N)....
243 1RE8 Ki = 0.3 nM BD2 C27 H26 N2 O6 c1ccc(c(c1....
244 1REJ Ki = 5 nM B1L C20 H22 N2 O5 c1cc(ccc1C....
245 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
246 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
247 5IZF Kd = 1.7 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
248 2VZ6 - FEF C20 H19 N3 O4 c1ccc2c(c1....
249 2Z7Q - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
250 2Z7R ic50 = 3 nM STU C28 H26 N4 O3 C[C@@]12[C....
251 4UZH ic50 = 9800 nM JVE C15 H13 F N4 O c1ccc(c(c1....
252 2C6E - HPM C28 H31 N7 O4 COc1cc2c(c....
253 3H0Y ic50 = 0.006 uM 48B C23 H17 Cl F N5 O2 c1ccc(c(c1....
254 4B0G ic50 = 0.015 uM VEK C19 H21 Br N8 O Cc1cc(no1)....
255 4JBP ic50 = 41 nM YPH C34 H36 N6 O4 c1ccc(cc1)....
256 3H10 - 97B C30 H25 Cl F2 N6 O CN1CCN(CC1....
257 1MQ4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
258 5EW9 Ki < 0.01 nM 5VC C22 H21 Cl F N3 O3 S c1cc(nc(c1....
259 4CEG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
260 3DJ6 - AK6 C25 H24 N4 O3 S COc1ccc(cc....
261 2WQE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
262 3FDN ic50 = 0.033 uM MMH C21 H22 N6 O3 Cc1c(c([nH....
263 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
264 5DR9 - 5E2 C16 H9 Br Cl N O2 c1cc(cc(c1....
265 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
266 5DN3 Kd = 3.77 uM 5DN C16 H9 Br F N O2 c1cc(cc(c1....
267 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
268 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
269 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
270 5DT0 - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
271 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
272 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
273 5DR2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
274 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
275 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
276 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
277 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
278 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
279 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
280 5DRD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
281 5DPV - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
282 4UYN ic50 = 2 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
283 5DT3 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
284 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
285 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
286 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
287 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
288 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
289 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
290 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
291 4KS7 - X4Z C25 H28 N8 O S Cc1nc2ccsc....
292 1M2P - HNA C14 H7 N O6 c1cc2c(c(c....
293 1LPU - BEN C7 H8 N2 [H]/N=C(c1....
294 2QC6 ic50 = 0.1 uM G12 C10 H6 Br2 O3 CC1=C(C(=O....
295 4ANM ic50 = 28 nM WUL C15 H14 Br N3 O3 c1cc2c(cc1....
296 1DAW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
297 4RLK - E91 C21 H14 N2 O2 c1ccc2c(c1....
298 2OXD - K32 C7 H2 Br4 N2 O c12c(c(c(c....
299 2PVM Ki = 0.36 uM P29 C17 H15 N9 c1ccc(cc1)....
300 1J91 - TBS C6 H Br4 N3 c12c(c(c(c....
301 4DGO ic50 = 0.57 uM 0JW C10 H10 N2 O3 c1cc(c(cc1....
302 3FL5 - TXQ C14 H8 O6 c1cc(c(c2c....
303 3PWD ic50 = 0.22 uM CZ0 C14 H9 N O5 CC1=CC(=O)....
304 3KXH - K66 C11 H9 Br4 N3 O2 CN(C)c1nc2....
305 4DGM ic50 = 1.2 uM AGI C15 H10 O5 c1cc(ccc1C....
306 3PVG - K68 C9 H4 Br4 N2 O2 c1nc2c(n1C....
307 1ZOG Ki = 0.07 uM K37 C8 H4 Br4 N2 S CSc1[nH]c2....
308 2PVJ Ki = 0.005 uM P44 C19 H21 N7 c1ccc(cc1)....
309 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
310 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
311 2OXY - K17 C7 H2 Br4 N2 c1[nH]c2c(....
312 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
313 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
314 2PVL Ki = 0.024 uM P55 C18 H20 N8 CCN1CCN(CC....
315 1LP4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
316 2PVN Ki = 0.00035 uM P63 C20 H16 N8 O CC(=O)Nc1c....
317 3KXG - K6X C7 H Br5 N2 c12c(c(c(c....
318 3BE9 Ki = 24 nM P04 C19 H21 N7 O c1cc2cc(c1....
319 2OXX - K22 C7 H2 Br4 N2 S c12c(c(c(c....
320 3KXM - K74 C11 H9 Br4 N3 O S CNC(=O)CSc....
321 1LR4 - BEN C7 H8 N2 [H]/N=C(c1....
322 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
323 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
324 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
325 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
326 1JKL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
327 3F5G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
328 5AUZ ic50 = 98 uM GEN C15 H10 O5 c1cc(ccc1C....
329 1P4F - DRG C12 H11 N3 c1ccc-2c(c....
330 4TXC Kd = 0.24 uM 38G C24 H27 N5 O3 CN(C)CCN[C....
331 2YAK ic50 = 2 nM OSV C27 H31 F N4 O3 Ru S4 CC(C)Oc1cc....
332 5AUY ic50 = 1.6 uM MRI C15 H10 O7 c1cc(c(cc1....
333 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
334 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
335 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
336 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
337 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
338 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
339 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
340 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
341 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
342 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
343 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
344 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
345 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
346 2XK6 - EQH C18 H21 N3 O2 S c1csc(c1C2....
347 2WQO - VGK C21 H20 N2 O5 COc1cc(cc(....
348 2XKE ic50 = 4.2 uM WI2 C17 H20 N4 O3 COc1cccc(c....
349 2XNN - 430 C21 H16 F3 N3 O2 S C[C@H](c1c....
350 2XK7 ic50 = 1.5 uM 30E C21 H28 N4 O5 CC[C@H]1C[....
351 3QD4 ic50 = 0.00000001 M 3Q6 C22 H30 N8 O2 C[C@@H]1C[....
352 3RCJ ic50 = 0.8 uM 3RC C16 H13 N5 c1ccc(cc1)....
353 2PE0 - 39Z C14 H12 N2 O2 CC(c1ccc[n....
354 4CT2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
355 5ACK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
356 3HRC - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
357 5LVM - ADE C5 H5 N5 c1[nH]c2c(....
358 5MRD ic50 = 36.4 uM S26 C18 H13 Cl N2 O4 S2 CCOC(=O)C1....
359 3ION ic50 = 8 nM 8H1 C28 H27 N5 O3 COc1cc2c3c....
360 1UU7 ic50 = 14 uM BI2 C27 H26 N4 O2 C[N@@]1CCC....
361 3HRF Kd = 10.3 uM P47 C17 H15 Cl O2 c1ccc(cc1)....
362 3QCS ic50 = 0.00000001 M 3Q1 C15 H17 N7 O c1cc2c(cc1....
363 1H1W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
364 4AW1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
365 2PE2 - 464 C28 H30 N6 O3 c1cc(cc(c1....
366 3H9O ic50 = 70 nM 9BD C19 H19 N5 O3 COCCOc1cc2....
367 1Z5M ic50 = 30 nM LI8 C23 H31 Br N8 O3 CC(C)(C(=O....
368 5HKM ic50 = 0.013 uM 61Y C16 H15 N7 CCc1cc(nc(....
369 3QD0 ic50 = 0.00000001 M 3Q4 C24 H26 N8 O C[C@@H]1CC....
370 3ORZ - BI4 C27 H26 N4 O2 C[N@]1CCC[....
371 5LVN Kd = 20 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
372 2XCH ic50 = 374 nM CKG C22 H25 N7 O c1c2c(nc(n....
373 4AW0 - MJF C18 H15 Cl O5 c1ccc(cc1)....
374 3OTU - BI4 C27 H26 N4 O2 C[N@]1CCC[....
375 3QCX ic50 = 0.00000001 M 3Q2 C16 H19 N7 O C[C@@H]1CO....
376 1UU3 ic50 = 0.75 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
377 5LVL Kd = 1.25 uM 537 C14 H8 N2 O c1ccc2c(c1....
378 3QC4 ic50 = 0.002 uM MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
379 3QCY ic50 = 0.00000001 M 3Q3 C22 H22 N8 O2 c1ccc(cc1)....
380 1UU8 ic50 = 9 uM BI1 C25 H24 N4 O2 CN(C)CCCn1....
381 4CT1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
382 4A07 - AZ7 C17 H13 Cl3 N2 O2 c1cc(ccc1[....
383 2JDO ic50 = 0.23 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
384 1O6K - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
385 3E88 Ki = 2 nM G96 C24 H27 N7 O3 CCn1c2cc(n....
386 3D0E ic50 = 13 nM G93 C21 H27 N7 O3 CCn1c2c(cn....
387 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
388 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
389 4QMP ic50 = 0.014 uM DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
390 4U8Z - 3FE C17 H15 N5 O c1cc(cc(c1....
391 4QMX ic50 = 11 uM H8H C27 H32 Cl N5 O5 CN1CCN(CC1....
392 4QMT ic50 = 0.01 uM H1N C29 H32 N4 O3 S CCS(=O)(=O....
393 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
394 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
395 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
396 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
397 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
398 4NUS ic50 = 0.005 uM 2NK C22 H21 F2 N3 O CN1CCN(CC1....
399 4NW6 ic50 = 0.004 uM 2NS C23 H20 N4 O4 COc1cc(cc(....
400 4NW5 ic50 = 0.02 uM 2NR C23 H21 F N2 O5 COc1cccc(c....
401 4EL9 - AFE C21 H20 O10 C[C@H]1[C@....
402 5D9L ic50 = 0.024 uM 583 C15 H12 N2 O2 c1cc(ccc1c....
403 4FII - ARG PRO LYS PRO LEU VAL ASP PRO n/a n/a
404 4JDK - ARG ARG ARG ARG SER TRP TYR n/a n/a
405 2W7X ic50 = 138 nM D1A C18 H17 N7 O3 [H]/N=C(N)....
406 4A9U - A9U C27 H28 N4 O2 c1ccc(cc1)....
407 2YCF ic50 = 0.7 nM YCF C19 H24 N10 O3 [H]/N=C(N/....
408 4BDI ic50 = 227.7 uM HAU C14 H19 N3 O2 Cc1ccc(nc1....
409 2YCR ic50 = 69.6 nM HCW C23 H28 N10 O C/C(=NNC1=....
410 2WTJ ic50 = 0.7 uM WTJ C16 H20 N4 O3 S CN(C)CCNC(....
411 2YIT ic50 = 0.29 nM YIT C21 H24 N6 O2 CCC/C(=NNC....
412 2W0J ic50 = 240 nM ZAT C19 H24 N10 O [H]/N=C(N)....
413 2XK9 ic50 = 0.03 nM XK9 C18 H17 N7 O4 C/C(=NNC(=....
414 2YCS ic50 = 1.36 nM NXP C18 H18 N6 O C/C(=NNC(=....
415 2WTI ic50 = 0.092 uM WTI C18 H15 N3 O3 S c1cc(ccc1c....
416 2YIR ic50 = 0.17 nM YIR C20 H19 N7 O3 [H]/N=C(N)....
417 2XBJ ic50 = 0.86 uM XBJ C23 H27 F N4 O4 CC(C)([C@@....
418 2XM9 ic50 = 0.009 uM LWH C21 H20 N6 O c1ccc2c(c1....
419 2YIQ ic50 = 12.67 nM YIQ C20 H19 N7 O C/C(=NNC(=....
420 2CN5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
421 4FG9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
422 4FG8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
423 5L2T - 6ZZ C23 H30 N8 O CN(C)C(=O)....
424 5L2S - 6ZV C27 H32 F2 N8 CCN1CCN(CC....
425 4AUA ic50 = 7.2 uM 4AU C12 H9 N3 O c1ccc2c(c1....
426 2WEI ic50 = 3.4 nM VGG C17 H21 N5 Cc1cccc(c1....
427 3CQW ic50 = 42 nM CQW C12 H11 Cl N6 c1c(c2c([n....
428 4GV1 ic50 = 3 nM 0XZ C21 H25 Cl N6 O2 c1cc(ccc1[....
429 3MVH ic50 = 0.5 nM WFE C20 H22 F2 N6 O CCc1c[nH]c....
430 3MV5 ic50 = 180 nM XFE C11 H15 N5 Cc1c[nH]c2....
431 3QKL - SMR C29 H40 N4 O5 S CCOCC[N@@]....
432 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
433 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
434 3GC0 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
435 3MFU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
436 3C0H - AMP C10 H14 N5 O7 P c1nc(c2c(n....
437 3C0I - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
438 3MFS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
439 3C0G - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
440 3MFR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
441 4OTH ic50 = 9 nM DRN C25 H23 N5 O2 S [H]/N=C(/N....
442 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
443 4APP Ki = 0.064 uM N53 C33 H36 N6 O3 CC1(c2c(c(....
444 4NJD ic50 = 0.79 uM NJD C21 H20 N8 O COc1nc(nc(....
445 2YAB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
446 2YAA - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
447 3A62 - STU C28 H26 N4 O3 C[C@@]12[C....
448 3WF9 ic50 = 567 nM FS7 C24 H25 N3 O5 S C[C@H]1CCc....
449 3WF8 ic50 = 232 nM F76 C23 H23 N3 O5 S c1ccc2c(c1....
450 4L3L - 5FI C19 H21 F3 N6 CCc1cncnc1....
451 3WE4 ic50 = 15 nM 5FI C19 H21 F3 N6 CCc1cncnc1....
452 3WF7 ic50 = 206 nM FS9 C18 H17 F3 N6 O c1cc(cc(c1....
453 4L3J - 5FI C19 H21 F3 N6 CCc1cncnc1....
454 3WF6 ic50 = 33 nM FZ9 C18 H16 N6 c1ccc2c(c1....
455 4AU8 ic50 = 551 nM Z3R C11 H8 N2 O2 S3 c1ccc2c(c1....
456 4O0R Ki = 0.036 uM X4Z C25 H28 N8 O S Cc1nc2ccsc....
457 5IME Ki = 4.6 nM 6BZ C22 H22 Cl N7 O2 CC1=NC=CN(....
458 4ZY6 Ki = 5 nM 4T6 C18 H17 Cl N8 c1cc2c(c(c....
459 3Q53 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
460 4EQC ic50 = 0.008 uM XR1 C29 H28 Cl N7 O S CCN1c2c(cn....
461 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
462 5AX9 ic50 = 8 nM 4KT C24 H24 N4 O3 COc1ccc(cc....
463 4EQU - G6I C30 H24 F3 N7 O2 Cc1ccc(cc1....
464 4JR7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
465 4JQE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
466 4MWH - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
467 4LFI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
468 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
469 4OBQ ic50 = 0.065 uM 2QT C20 H20 F N5 O c1cc2c(cc1....
470 4U43 Kd = 48 uM 3D8 C11 H9 N5 c1cc(cnc1)....
471 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
472 1QL6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
473 1PHK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
474 5F9E ic50 = 0.46 nM 5VS C23 H21 N5 O2 CC1(NC(=O)....
475 1XJD Ki = 0.33 nM STU C28 H26 N4 O3 C[C@@]12[C....
476 3M2W ic50 < 0.003 uM L8I C23 H21 F N4 O CN1CC2(C1)....
477 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
478 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
479 5DBX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
480 2VN9 - GVD C22 H19 N7 c1ccc2c(c1....
481 4EJN ic50 = 0.005 uM 0R4 C33 H26 F N7 O2 CC(=O)Nc1c....
482 4WNO ic50 = 160 nM 3RF C20 H19 N7 c1ccc2c(c1....
483 4WNP ic50 = 8 nM 3RJ C22 H20 N8 c1ccc2c(c1....
484 5CI7 ic50 = 120 nM 51W C18 H24 I N7 O c1cc(cc(c1....
485 5M56 - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
486 5M4U - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
487 3OFM - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
488 2V7O - DRN C25 H23 N5 O2 S [H]/N=C(/N....
489 3TXO ic50 = 9 nM 07U C17 H19 N5 CC(C)(CNc1....
490 4USF - 6UI C19 H15 N3 O COc1ccc2cc....
491 1V0P ic50 = 0.13 uM PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
492 1V0O ic50 = 5.5 uM INR C16 H10 N2 O5 S c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: MI1; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 MI1 1 1
2 7GV 0.678571 0.836066
3 7GT 0.581633 0.666667
4 0NU 0.421569 0.816667
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4OTH; Ligand: DRN; Similar sites found: 341
This union binding pocket(no: 1) in the query (biounit: 4oth.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3W0O ADP 0.0002355 0.41945 1.46628
2 3W0O HY0 0.0002355 0.41945 1.46628
3 2AQX ATP 0.002402 0.41678 1.7301
4 5MRH Q9Z 0.0001872 0.5062 1.75953
5 1M0W ANP 0.001111 0.40685 1.75953
6 1TZD ADP 0.0003528 0.50714 1.81818
7 4GQP B40 0.01951 0.40408 2.00803
8 3DNT ATP 0.000649 0.44432 2.05279
9 4OYA 1VE 0.02353 0.4108 2.05279
10 3TPV ADE 0.007125 0.40346 2.05279
11 3TDV GDP 0.000001856 0.56604 2.28758
12 1IOW PHY 0.001451 0.44312 2.28758
13 1IOW ADP 0.001451 0.44312 2.28758
14 1OBD ATP 0.000295 0.42063 2.28758
15 2G50 PYR 0.006996 0.43231 2.34604
16 4O4F IHP 0.003874 0.41478 2.41935
17 4O4F ATP 0.003848 0.41333 2.41935
18 1IA9 ANP 0.00001413 0.52093 2.5
19 5TVA AMP 0.007954 0.41608 2.5
20 2GC0 PAN 0.006691 0.40812 2.65957
21 1ZP9 ATP 0.000002718 0.57309 2.71318
22 1ZTH ADP 0.0000005409 0.51328 2.71318
23 4ZS4 ATP 0.00001654 0.51796 2.9316
24 3WVR AMP 0.0002573 0.48135 2.93255
25 4NS0 PIO 0.01 0.4208 3.00752
26 3RE4 TO1 0.00001451 0.46646 3.10078
27 3K5I ADP 0.0006469 0.43694 3.22581
28 5T96 79J 0.009596 0.42896 3.22581
29 3K5I AIR 0.003058 0.42632 3.22581
30 3I0O ADP 0.00006796 0.52111 3.24484
31 5C1P DAL DAL 0.003892 0.41312 3.26797
32 5C1P ADP 0.0007292 0.41108 3.26797
33 3PDT ADP 0.00001321 0.48212 3.27273
34 5TT6 ATP 0.003346 0.41077 3.29949
35 3X01 AMP 0.0004903 0.49427 3.30789
36 5IGI ZIT 0.01275 0.40481 3.32226
37 5IGI GMP 0.01207 0.40481 3.32226
38 4XBA GMP 0.009203 0.41306 3.5
39 4CYI ATP 0.000005471 0.5196 3.51906
40 4OCV ANP 0.0001029 0.48347 3.51906
41 3VOT ADP 0.0003875 0.41887 3.51906
42 3B2Q AES 0.02111 0.41522 3.51906
43 2OBM ADP 0.02887 0.40085 3.51906
44 2YW2 ATP 0.001052 0.43559 3.53774
45 2PYW ADP 0.000009035 0.51235 3.81232
46 4OCJ NDG 0.0001572 0.48973 3.81232
47 4U98 ACP 0.0003463 0.47018 3.81232
48 1EHI ADP 0.0004009 0.45782 3.81232
49 1PK8 ATP 0.000204 0.44161 3.81232
50 4UWJ 7L5 0.03424 0.40359 3.81232
51 4UWJ MYA 0.03424 0.40359 3.81232
52 4XBT FLC 0.01001 0.40746 3.87097
53 4XBT 3ZQ 0.009449 0.40144 3.87097
54 3NV6 CAM 0.0361 0.40958 3.9823
55 1UNQ 4IP 0.01906 0.41179 4
56 3KAL ADP 0.001618 0.43973 4.10557
57 5COU ATP 0.001081 0.41172 4.11765
58 2IF8 ADP 0.0002095 0.40702 4.13223
59 3VSV XYS 0.01288 0.41816 4.23198
60 5GZ9 ANP 0.0000001611 0.59358 4.2623
61 2VPQ ANP 0.0002482 0.45994 4.39883
62 5VZ0 ADP 0.000177 0.4452 4.39883
63 3V4S ATP 0.0009656 0.43328 4.39883
64 3V4S ADP 0.006017 0.41711 4.39883
65 1F52 ADP 0.01028 0.41077 4.39883
66 1T36 ADP 0.005291 0.41048 4.39883
67 3AB4 THR 0.0232 0.40141 4.49438
68 2BES RES 0.008532 0.41463 4.65116
69 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.003698 0.43193 4.66926
70 3ETH ATP 0.0007281 0.43839 4.69208
71 3VPB ADP 0.00004755 0.49424 4.96454
72 3VPC ADP 0.000177 0.464 4.96454
73 1GT4 UNA 0.004288 0.42056 5.03145
74 5W2I ADP 0.0007342 0.44206 5.05837
75 5W2I I3P 0.0007342 0.44206 5.05837
76 3EW2 BTN 0.01923 0.40151 5.18518
77 4XYM A12 0.001914 0.41397 5.21739
78 4GYI ADP 0.00002382 0.5361 5.27859
79 5MW8 ATP 0.00001525 0.51073 5.27859
80 2R2N KYN 0.02409 0.40043 5.27859
81 1S9D AFB 0.01875 0.40205 5.4878
82 4OUC 5ID 0.0000001038 0.55385 5.57185
83 2PUL ACP 0.005699 0.4215 5.57185
84 4ANW O92 0.0001414 0.42052 5.57185
85 1W2D ADP 0.0004023 0.48349 5.66038
86 2XG5 EC5 0.003405 0.43954 5.78035
87 2XG5 EC2 0.003405 0.43954 5.78035
88 3AKK ADP 0.00002918 0.48662 5.84615
89 4PU5 ANP 0.0006712 0.43439 5.8651
90 1I7L ATP 0.0002042 0.46549 6.14887
91 5IQD RIO 0.000009479 0.5439 6.15836
92 5IQD GNP 0.000008744 0.5439 6.15836
93 5C4L 4XR 0.000009442 0.53396 6.15836
94 5C4L SIS 0.00009413 0.49062 6.15836
95 4AZT LY2 0.001831 0.45143 6.15836
96 4DFU QUE 0.006705 0.43341 6.15836
97 5FS0 5JC 0.006177 0.43029 6.16114
98 4FE2 AIR 0.002813 0.44234 6.27451
99 4FE2 ADP 0.003994 0.43034 6.27451
100 2CFM AMP 0.001494 0.45573 6.41711
101 2BKK ADP 0.0001208 0.43921 6.43939
102 5I35 ANP 0.0000003687 0.60507 6.45161
103 1UPR 4IP 0.03714 0.40797 6.50407
104 3HEE R5P 0.01745 0.40765 6.71141
105 3UDZ ADP 0.00001327 0.49865 6.74487
106 2QK4 ATP 0.0002805 0.41235 6.74487
107 3P7G MAN 0.02057 0.40902 6.84932
108 3ORQ ADP 0.001029 0.42872 7.33138
109 2W5P CL8 0.007004 0.43768 7.38255
110 4GID 0GH 0.01752 0.41077 7.62463
111 4LRJ ANP 0.000000136 0.55979 7.69231
112 5LXT ACP 0.003345 0.40603 7.69231
113 1QKQ MAN 0.001967 0.44601 7.74648
114 1TQP ATP 0.000005673 0.50977 7.80142
115 2V58 LZJ 0.001478 0.4531 7.91789
116 4R78 AMP 0.00006399 0.52949 8.21114
117 5A89 FMN 0.01968 0.40201 8.33333
118 5A89 ADP 0.01797 0.40201 8.33333
119 4WW7 AMP 0.000001345 0.55232 8.42912
120 2Q7D ANP 0.005407 0.40859 8.5044
121 2GQS C2R 0.001339 0.44809 8.86076
122 2GQS ADP 0.001695 0.43887 8.86076
123 2GQR ADP 0.002274 0.40248 8.86076
124 4AZW ATP 0.0002024 0.45705 8.9172
125 3ZJX BOG 0.0004616 0.49763 8.99654
126 2G30 ALA ALA PHE 0.002169 0.4026 9.09091
127 4Q5H ANP 0.0000004477 0.54981 9.21053
128 3HAV ATP 0.00253 0.42267 9.38416
129 3Q60 ATP 0.00001177 0.48801 10.2639
130 2IO8 ADP 0.0001459 0.4544 10.2639
131 2YRX AMP 0.00499 0.44097 10.5572
132 4CS9 AMP 0.007611 0.4085 11.1111
133 2VQD AP2 0.0002109 0.46527 11.1437
134 1BHX ASP PHE GLU GLU ILE 0.008688 0.41843 11.4286
135 2CSN CKI 0.00006373 0.52675 14.4781
136 4O1P ANP 0.00000002073 0.60076 14.956
137 5K2M ADP 0.0006372 0.44465 15.0943
138 5DMZ ADP 0.00000002312 0.65057 15.5425
139 5CKW ANP 0.00000155 0.4973 15.8358
140 2V73 SIA 0.02538 0.40594 17.2775
141 4OAV ACP 0.00000001344 0.67032 17.8886
142 4I94 ANP 0.00000006117 0.57224 18.6667
143 3G08 FEE 0.02585 0.40358 19.1919
144 5MY8 RXZ 0.0000002793 0.5888 19.3548
145 3GC8 B45 0.000003523 0.5349 19.3548
146 5C03 AGS 0.000000437 0.55043 21.1144
147 4WOV 3SM 0.000005837 0.56513 21.7666
148 4IX4 ADP 0.0000006039 0.55983 22.5806
149 5AWM ANP 0.000001003 0.61027 22.8739
150 5N87 N66 0.000000002839 0.69613 23.0032
151 3VHE 42Q 0.0000003302 0.51208 23.1672
152 5KO1 6UY 0.0000003039 0.5485 23.6749
153 4YZC STU 0.0000000105 0.67316 23.7537
154 4UX9 ANP 0.000000009167 0.65082 24.0469
155 4IZY 1J2 0.00000002799 0.6302 24.0469
156 3PTG 932 0.000000002616 0.57106 24.3402
157 3TTI KBI 0.0000001318 0.54614 24.3402
158 5W4W 9WG 0.000005869 0.54292 24.4713
159 4KBA 1QM 0.00006782 0.44971 24.4713
160 5DRB 5FJ 0.000004224 0.41429 24.7423
161 4D2S DYK 0.0000006217 0.51364 25.7042
162 3GNI ATP 0.0000001431 0.5846 25.8065
163 2PZI AXX 0.000005411 0.56669 25.8065
164 4F9C 0SX 0.000000008863 0.6015 26.0997
165 5BVE 4VG 0.0000000688 0.6687 26.3158
166 4G17 0VN 0.00001141 0.48079 26.3636
167 4Y8D 49J 0.0000012 0.57445 26.393
168 5LPZ ADP 0.00000002799 0.59749 26.506
169 4NTX AMR 0.01763 0.40382 26.6667
170 4XH0 ADP 0.0000007925 0.63992 26.6862
171 4OH4 ANP 0.0000000587 0.58523 26.7267
172 1U5R ATP 0.0000000115 0.66403 27.2727
173 4BTK DTQ 0.0000008702 0.53952 27.2727
174 4M69 ANP 0.0000004057 0.56753 27.5618
175 2WU6 DKI 0.000000001033 0.68553 27.8592
176 5UIU 8CG 0.00000009801 0.61781 27.8638
177 4QTB 38Z 0.00000001456 0.65112 28.1525
178 4CRL C1I 0.0000001753 0.61325 28.1525
179 5X8I SQZ 0.0000000003848 0.72952 28.4457
180 5T8O 76Z 0.000002391 0.54803 28.4457
181 4NFN 2KC 0.000006121 0.5003 28.479
182 4IDT T28 0.00000001097 0.60245 28.739
183 4P5Z Q7M 0.000002663 0.56839 28.739
184 3E7O 35F 0.000003492 0.55458 28.739
185 1K3A ACP 0.0000002076 0.53863 28.7625
186 4E93 GUI 0.000000209 0.50688 29.0323
187 5EKO N17 0.0009502 0.43549 29.0323
188 4Y0X ADP 0.0000003182 0.54181 29.0667
189 4IJP 1EH 0.0000002059 0.57911 29.3255
190 3H9R TAK 0.000007552 0.57584 29.3939
191 4EUU BX7 0.0000000107 0.5909 29.4671
192 2H8H H8H 0.000000034 0.64314 29.6188
193 5LXC 7AA 0.0000000005737 0.63535 29.6188
194 1OUK 084 0.00000163 0.6321 29.6188
195 2RIO ADP 0.00000001717 0.59665 29.6188
196 1Y57 MPZ 0.0000009556 0.54891 29.6188
197 3C1X CKK 0.00009404 0.47545 29.6188
198 4LOO SB4 0.00004074 0.47234 29.6188
199 3LXN MI1 0.0000000006768 0.69897 30.1887
200 4FL3 ANP 0.0000000009621 0.68343 30.2053
201 4YLL 4E3 0.00000005074 0.61462 30.2053
202 5LPB ADP 0.000001423 0.50425 30.4054
203 4U44 3D9 0.00000006683 0.57961 30.4217
204 5HVJ ANP 0.000000002381 0.78337 30.4762
205 1Q8Y ADP 0.00000005467 0.6025 30.7918
206 1Q8Y ADE 0.0000007787 0.49794 30.7918
207 4H3P ANP 0.000000001718 0.70068 31.085
208 2B9I ADP 0.0000001123 0.62011 31.085
209 4H3Q ANP 0.0000001244 0.59829 31.085
210 2B9H ADP 0.0000001462 0.57824 31.085
211 2B9J ADP 0.00000008105 0.57329 31.085
212 5EOB 5QQ 0.000003803 0.58042 31.348
213 2B9F ADP 0.0000001386 0.57192 31.3783
214 3PP0 03Q 0.000006675 0.49133 31.6568
215 5BYZ 4WE 0.00000005907 0.62959 31.6716
216 3E8N VRA 0.00000007812 0.4584 31.6716
217 3E8N ATP 0.00000007812 0.4584 31.6716
218 5HCY 60D 0.0000001765 0.62918 31.7221
219 3LXK MI1 0.00000002276 0.64027 31.8043
220 3NW7 LGV 0.000006011 0.56269 31.9218
221 4Y85 499 0.000001311 0.52429 31.9277
222 5NKB 8ZT 0.000002555 0.43377 32.0261
223 4GJ3 0XP 0.00000004835 0.53226 32.1192
224 1CM8 ANP 0.000008795 0.49566 32.2581
225 5HX8 66P 0.000000006839 0.60081 32.4503
226 5MJA 7O3 0.00002356 0.46948 32.459
227 5HES 032 0.000001835 0.5467 32.5733
228 5TO8 7FM 0.000000385 0.60742 32.6241
229 3ALN ANP 0.0000003322 0.57046 32.7217
230 4QMN DB8 0.00000001233 0.52031 32.9032
231 2XVD AS6 0.000002245 0.49558 33.1126
232 1OPK P16 0.00000501 0.46563 33.1378
233 3PLS ANP 0.0000000001822 0.66778 33.2215
234 4BKJ STI 0.00088 0.44052 33.3333
235 2JLD AG1 0.00000000001028 0.79842 33.7243
236 3UIM ANP 0.00000002468 0.64932 33.7423
237 4CLI 5P8 0.0000004544 0.61064 33.945
238 4NM5 ADP 0.0002375 0.49441 34.0176
239 5HQ0 LZ9 0.00000000764 0.63723 34.106
240 5USZ SKE 0.0000003113 0.59163 34.2561
241 3F7Z 34O 0.0000000002553 0.67212 34.3109
242 4NST ADP 0.00000005798 0.5846 34.3109
243 3ZRM ZRM 0.0000005207 0.54745 34.3109
244 4Y93 746 0.0000009906 0.52871 34.3109
245 4E1Z 0MX 0.000000006174 0.63632 34.3643
246 4G31 0WH 0.00001365 0.43414 34.4482
247 3KN5 ANP 0.000000006952 0.58906 34.4615
248 5EFQ ADP 0.00000002435 0.59878 34.6041
249 3KRL KRL 0.0000002806 0.58069 34.6269
250 3DLS ADP 0.00000003142 0.57361 34.6269
251 2Y6O 1N1 0.00003666 0.4925 34.7079
252 2QLU ADE 0.000002374 0.41386 34.7134
253 3VRY B43 0.000007867 0.49553 34.8974
254 3KRR DQX 0.00000002935 0.6885 34.9153
255 5JGA 6KC 0.0000002293 0.50185 34.9206
256 4AT3 LTI 0.00000322 0.48008 35.1171
257 4BHN BH9 0.000000009721 0.63218 35.3293
258 3HMO STU 0.000000008067 0.60298 35.4839
259 4XV1 904 0.00000007984 0.6282 35.6164
260 5JFS 6K0 0.0000004022 0.60825 35.7143
261 4U0I 0LI 0.00007806 0.49415 35.873
262 5H2U 1N1 0.00004784 0.50341 36.3296
263 4ASE AV9 0.000005325 0.53884 36.3636
264 5M06 ADP 0.000002367 0.50611 36.5942
265 5DA3 58V 0.0000005097 0.62459 36.6038
266 1VJY 460 0.0000002414 0.60514 36.6337
267 1BYG STU 0.000000005732 0.60246 36.6906
268 2WQN ADP 0.0000002053 0.63422 36.7742
269 2PVF ACP 0.0000000002661 0.74762 36.8263
270 5VCV 1N1 0.00000004908 0.58756 36.9775
271 5CEO 50D 0.000008966 0.49993 37
272 3GQI ACP 0.00000000497 0.6802 37.1166
273 4JDI ANP 0.00000004516 0.60564 37.2434
274 3BU5 ATP 0.00000001214 0.6087 37.2549
275 4CQE CQE 0.000004219 0.53164 37.4101
276 3EKK GS2 0.000000136 0.49057 37.4593
277 5TA6 79D 0.00000004917 0.55882 37.5367
278 4K33 ACP 0.000000004306 0.63759 37.5385
279 1U59 STU 0.0000000003095 0.73372 37.6307
280 2BPM 529 0.000000005209 0.46624 37.8641
281 4YZN 4K5 0.0000000004027 0.70267 37.9791
282 5U6C 7YS 0.000000339 0.57727 38.0952
283 3HZT J60 0.00000002587 0.68762 38.1232
284 3FC2 IBI 0.0002099 0.50938 38.209
285 2X2M X2M 0.00000004952 0.61209 38.2166
286 2OO8 RAJ 0.001766 0.42235 38.8013
287 4YMJ 4EJ 0.0000001014 0.68714 38.8158
288 2WEL K88 0.0000002206 0.47994 38.8379
289 3IGO ANP 0.00000002543 0.62415 39.0029
290 5VC5 96M 0.00000001497 0.64805 39.1003
291 4F4P 0SB 0.000004476 0.58156 39.1941
292 5UR1 YY9 0.0000001508 0.63065 39.2283
293 4AG8 AXI 0.0000001368 0.48734 39.2405
294 4EWH T77 0.00000005223 0.55583 39.2727
295 4N70 2HX 0.000000000769 0.74305 39.3293
296 3SRV S19 0.00000000282 0.62452 39.3502
297 3SLS ANP 0.0000000175 0.63092 39.4737
298 3G5D 1N1 0.0000004091 0.62647 39.5105
299 5JKG 6LF 0.00000011 0.62985 39.5498
300 4CFU 2WC 0.000000006013 0.69634 39.604
301 4BCN T9N 0.00000001358 0.69027 39.6667
302 4X7Q 3YR 0.0000000008657 0.71389 39.7436
303 4BFM ANP 0.0000000002132 0.72031 39.8204
304 4BCQ TJF 0.0000002075 0.52765 39.8671
305 4BCM T7Z 0.00000007143 0.51234 39.8671
306 3ORK AGS 0.00000007169 0.57198 39.8714
307 3RI1 3RH 0.000000002053 0.68217 39.9361
308 5LMK 6ZK 0.000001527 0.51011 40.0673
309 4A4X JUP 0.0000003944 0.58488 40.1434
310 3BZ3 YAM 0.0000003506 0.40311 40.2174
311 2F57 23D 0.00000009881 0.63991 40.3785
312 3KMW ATP 0.0003525 0.43431 40.5904
313 5IH9 6BF 0.000000001643 0.7066 40.597
314 5DH3 5BS 0.00000003418 0.62651 40.6349
315 2HY0 306 0.00000001491 0.68835 40.9938
316 3SXF BK5 0.000000003058 0.54198 41.0557
317 5DEY 59T 0.0000001556 0.64331 41.0774
318 3CY2 MB9 0.000000005028 0.63891 41.7197
319 4I6H 1C8 0.000008004 0.50107 41.8831
320 4TWP AXI 0.0000002872 0.62117 42.0664
321 2OFV 242 0.000006247 0.54874 42.2383
322 5FBN 5WF 0.000003331 0.55907 42.4354
323 4XLI 1N1 0.00000806 0.54428 42.5373
324 2J7T 274 0.0266 0.40825 42.7152
325 1ZY5 ANP 0.0000001704 0.55474 42.9043
326 2X4Z X4Z 0.000000139 0.61967 42.9054
327 2A19 ANP 0.000000001643 0.74592 42.9577
328 4CSV STI 0.00006283 0.47467 43.2727
329 3O0G 3O0 0.00000001651 0.59417 43.4931
330 1UNH IXM 0.00000003607 0.56166 43.4931
331 5UOX 8GY 0.00000003129 0.6204 43.5424
332 2ZV2 609 0.00000008136 0.66339 43.6242
333 2HK5 1BM 0.000006954 0.51683 44.0741
334 5G1X ADP 0.000000004672 0.69115 44.5614
335 5L8L ADP 0.0000000009014 0.60095 44.5614
336 5LXM ADP 0.000000001492 0.6339 44.8763
337 3SXS PP2 0.000002975 0.53114 45.1493
338 5A6N U7E 0.00000000336 0.64143 45.583
339 3AQV TAK 0.000001367 0.52751 47.1014
340 3E5A VX6 0.00000002079 0.59109 48.5075
341 4L9I 8PR 0.00000003473 0.58147 48.6804
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