Receptor
PDB id Resolution Class Description Source Keywords
4OSP 2.25 Å EC: 1.-.-.- THE CRYSTAL STRUCTURE OF URDAMYCIN C-6 KETOREDUCTASE DOMAIN WITH BOUND NADP AND RABELOMYCIN STREPTOMYCES FRADIAE ROSSMANN FOLD KETOREDUCTASE NADPH BINDING OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX OXIDOREDUCTASE-ANTIBIOTIC
Ref.: STRUCTURE-BASED ENGINEERING OF ANGUCYCLINONE 6-KETOREDUCTASES. CHEM.BIOL. V. 21 1381 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
2V4 A:302;
Valid;
none;
submit data
338.311 C19 H14 O6 C[C@]...
NAP A:301;
Valid;
none;
submit data
743.405 C21 H28 N7 O17 P3 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4OSP 2.25 Å EC: 1.-.-.- THE CRYSTAL STRUCTURE OF URDAMYCIN C-6 KETOREDUCTASE DOMAIN WITH BOUND NADP AND RABELOMYCIN STREPTOMYCES FRADIAE ROSSMANN FOLD KETOREDUCTASE NADPH BINDING OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX OXIDOREDUCTASE-ANTIBIOTIC
Ref.: STRUCTURE-BASED ENGINEERING OF ANGUCYCLINONE 6-KETOREDUCTASES. CHEM.BIOL. V. 21 1381 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 4OSP - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 247 families.
1 4OSP - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
2 4KWH - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 4KWI - 1TJ C19 H12 O5 Cc1cc2c(c(....
4 4OSO - 2V4 C19 H14 O6 C[C@]1(Cc2....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 177 families.
1 4OSP - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 2V4; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 2V4 1 1
Ligand no: 2; Ligand: NAP; Similar ligands found: 127
No: Ligand ECFP6 Tc MDL keys Tc
1 NAP 1 1
2 NA0 0.881356 0.986301
3 TAP 0.872881 0.934211
4 NDO 0.840336 0.972603
5 NAD 0.811966 0.986111
6 N01 0.733871 0.958904
7 A3D 0.712 0.972603
8 NBP 0.707692 0.935065
9 NAD IBO 0.688 0.921053
10 NHD 0.68254 0.958904
11 NJP 0.661417 0.972973
12 NAJ PYZ 0.659091 0.898734
13 NFD 0.658915 0.934211
14 DND 0.619048 0.959459
15 NXX 0.619048 0.959459
16 ZID 0.605839 0.972603
17 NAQ 0.59854 0.922078
18 ATR 0.59292 0.917808
19 NAE 0.591241 0.946667
20 NDE 0.58042 0.986301
21 A22 0.571429 0.958904
22 AMP NAD 0.571429 0.933333
23 NAJ 0.567164 0.986111
24 A2R 0.563025 0.932432
25 NDC 0.561644 0.922078
26 NA7 0.552846 0.907895
27 ODP 0.551471 0.935065
28 A2P 0.539823 0.930556
29 8ID 0.537313 0.910256
30 NAD BBN 0.525974 0.865854
31 NPW 0.525547 0.8875
32 CNA 0.521739 0.959459
33 NZQ 0.521739 0.910256
34 NAD CJ3 0.519231 0.835294
35 NDP 0.514493 0.922078
36 PO4 PO4 A A A A PO4 0.503937 0.930556
37 DG1 0.503401 0.922078
38 1DG 0.503401 0.922078
39 NAD TDB 0.5 0.696078
40 TXP 0.5 0.922078
41 NMN AMP PO4 0.492958 0.921053
42 XNP 0.492958 0.875
43 25L 0.492308 0.958904
44 25A 0.492063 0.972222
45 NAD NDT 0.490909 0.747368
46 NMN 0.486726 0.888889
47 NGD 0.485714 0.935065
48 2AM 0.477876 0.891892
49 ADP 0.458333 0.945205
50 PAP 0.451613 0.931507
51 ADP MG 0.45082 0.906667
52 BEF ADP 0.447154 0.883117
53 ADP BEF 0.447154 0.883117
54 A2D 0.445378 0.945205
55 AN2 0.442623 0.932432
56 ADP PO3 0.44 0.944444
57 SAP 0.44 0.896104
58 AGS 0.44 0.896104
59 M33 0.439024 0.906667
60 AR6 AR6 0.438849 0.945205
61 BA3 0.438017 0.945205
62 ATP MG 0.436508 0.906667
63 ADP BMA 0.43609 0.92
64 OAD 0.43609 0.92
65 ATP 0.435484 0.945205
66 OOB 0.435115 0.958904
67 B4P 0.434426 0.945205
68 AP5 0.434426 0.945205
69 GAP 0.433071 0.92
70 0WD 0.432432 0.922078
71 5FA 0.432 0.945205
72 2A5 0.432 0.87013
73 AQP 0.432 0.945205
74 00A 0.428571 0.909091
75 CA0 0.427419 0.92
76 ALF ADP 0.426357 0.871795
77 ADP ALF 0.426357 0.871795
78 ACP 0.424 0.92
79 NAJ PZO 0.423841 0.897436
80 9SN 0.423358 0.897436
81 VO4 ADP 0.423077 0.932432
82 ANP MG 0.423077 0.896104
83 ADP VO4 0.423077 0.932432
84 WAQ 0.422222 0.884615
85 ACQ 0.421875 0.92
86 V3L 0.421875 0.945205
87 ADQ 0.421053 0.92
88 AR6 0.420635 0.918919
89 APR 0.420635 0.918919
90 ATP A A A 0.42029 0.958333
91 CO7 0.419753 0.786517
92 1ZZ 0.419118 0.841463
93 3OD 0.419118 0.92
94 DLL 0.41791 0.958904
95 AD9 0.417323 0.92
96 NAX 0.416667 0.875
97 OVE 0.416667 0.857143
98 MYR AMP 0.416058 0.841463
99 AV2 0.415385 0.868421
100 A3P 0.414634 0.944444
101 NNR 0.414414 0.72973
102 ALF ADP 3PG 0.413793 0.8625
103 OMR 0.413793 0.831325
104 LA8 ALF 3PG 0.413793 0.8625
105 ANP 0.410853 0.92
106 A1R 0.410448 0.860759
107 ABM 0.409836 0.893333
108 AMP 0.408333 0.944444
109 A 0.408333 0.944444
110 SON 0.408 0.933333
111 PPS 0.407692 0.829268
112 5AL 0.407692 0.932432
113 TYR AMP 0.407143 0.933333
114 NAI 0.406897 0.909091
115 7D3 0.406504 0.857143
116 DAL AMP 0.406015 0.932432
117 ADX 0.404762 0.829268
118 ATF 0.40458 0.907895
119 3UK 0.404412 0.945946
120 AMP DBH 0.404255 0.894737
121 139 0.402685 0.875
122 AMP MG 0.401639 0.893333
123 50T 0.401575 0.906667
124 SRP 0.401515 0.907895
125 A A 0.40146 0.972222
126 FA5 0.4 0.933333
127 3AM 0.4 0.90411
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4OSP; Ligand: 2V4; Similar sites found: 79
This union binding pocket(no: 1) in the query (biounit: 4osp.bio1) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1JXZ BCA 0.01624 0.4224 1.52091
2 1QX4 FAD 0.0313 0.41407 1.82482
3 3CMC NAD 0.03822 0.43094 1.90114
4 4O8A FAD 0.02162 0.41947 1.90114
5 1TIW TFB 0.03658 0.41426 1.90114
6 5X1M THG 0.0479 0.40079 2.28137
7 4QXB OGA 0.01342 0.40144 2.6616
8 1R6D DAU 0.04539 0.41923 3.04183
9 4R74 F6P 0.0274 0.40182 3.04183
10 4N14 WR7 0.007138 0.40104 3.04183
11 3HVJ 705 0.04484 0.40843 3.16742
12 4RSL FAD 0.0312 0.41616 3.42205
13 2P7Q GG6 0.004653 0.41225 3.7594
14 1SB8 UD2 0.00227 0.49258 3.80228
15 1SB8 NAD 0.008342 0.4577 3.80228
16 2BLE 5GP 0.02516 0.4123 3.80228
17 5LD5 NAD 0.0232 0.40867 3.80228
18 4U7W NDP 0.02729 0.41041 4.18251
19 1DFO PLG 0.02391 0.40325 4.56274
20 1EK6 UPG 0.006475 0.46932 5.70342
21 1EK6 NAI 0.007175 0.46532 5.70342
22 3L4S 3PG 0.03081 0.41339 5.70342
23 3L4S NAD 0.02942 0.41339 5.70342
24 4J7N GTG 0.02794 0.40294 5.70342
25 5U3F 7TS 0.02115 0.40766 6.46388
26 4CTA ATP 0.03349 0.40172 6.46388
27 1G4U AF3 0.01558 0.4005 6.52174
28 1I2B NAD 0.009402 0.45944 6.68317
29 5AGR A52 0.01717 0.40512 6.89655
30 2C29 DQH 0.0006245 0.41614 7.22433
31 4WXG 2BO 0.01927 0.41289 7.22433
32 4X7G NAP 0.006949 0.43083 7.56972
33 5KF6 TFB 0.02837 0.41533 7.60456
34 5KF6 FAD 0.02837 0.41533 7.60456
35 3CV9 VDX 0.01285 0.42909 7.98479
36 1NZY BCA 0.01753 0.42064 8.36502
37 4PIV 2W4 0.003946 0.43944 10.2662
38 1N7G GDR 0.04231 0.42298 10.6464
39 1XSE NDP 0.0009677 0.50262 12.9278
40 3QV1 NAD 0.02978 0.40579 14.6341
41 4NMC 2OP 0.04779 0.40596 15.9696
42 4NMC FAD 0.04969 0.40596 15.9696
43 1WMA AB3 0.04377 0.41421 24.7148
44 1WMA NDP 0.04377 0.41421 24.7148
45 3CH6 NAP 0.001584 0.50762 28.5171
46 3CH6 311 0.001584 0.50762 28.5171
47 4J7U NAP 0.02477 0.4272 31.9392
48 4J7U YTZ 0.02477 0.4272 31.9392
49 1A27 EST 0.02101 0.40068 33.0798
50 2BD0 BIO 0.003741 0.41592 33.8403
51 2VZ0 D64 0.001275 0.52166 39.924
52 2VZ0 NAP 0.001275 0.52166 39.924
53 3JQ9 AX1 0.004552 0.42446 40.3042
54 4CME KTZ 0.00607 0.42095 40.3042
55 4CM9 YGL 0.004979 0.41972 40.3042
56 3JQ8 DX3 0.00701 0.41476 40.3042
57 4CM8 IZ9 0.002556 0.40981 40.3042
58 3JQB DX6 0.008617 0.40815 40.3042
59 4CM4 4NR 0.009648 0.40796 40.3042
60 2DTX BMA 0.000255 0.53306 40.6844
61 4FC7 COA 0.01193 0.44477 40.6844
62 4FC7 NAP 0.01193 0.44477 40.6844
63 3AFN NAP 0.03519 0.41024 41.8605
64 3AI3 SOL 0.00006207 0.51199 42.2053
65 1ZMT RNO 0.00562 0.44948 42.5197
66 2WSB NAD 0.0007976 0.50721 43.3071
67 1HDC CBO 0.0002611 0.50362 44.8819
68 3H4V DVP 0.007673 0.45534 45.6274
69 3H4V NAP 0.008192 0.45284 45.6274
70 5ITV NAI 0.02022 0.42103 45.8824
71 2CFC KPC 0.0005631 0.46965 46
72 1NFQ NAI 0.01021 0.43813 46.9231
73 1AE1 NAP 0.01585 0.42902 47.5285
74 2Q2V NAD 0.04881 0.40247 47.8431
75 2AE2 NAP 0.00315 0.47461 48.0769
76 2AE2 PTO 0.00315 0.47461 48.0769
77 1XHL TNE 0.0004101 0.44703 49.0494
78 1XHL NDP 0.02431 0.41787 49.0494
79 1ZK4 NAP 0.0003342 0.52295 49.8008
Pocket No.: 2; Query (leader) PDB : 4OSP; Ligand: NAP; Similar sites found: 386
This union binding pocket(no: 2) in the query (biounit: 4osp.bio1) has 30 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1OYF MHN 0.01963 0.41895 None
2 1EBF NAD 0.0007243 0.4142 1.52091
3 5T9F TYR 0.003095 0.41274 1.52091
4 1YS4 NAP 0.0005613 0.40917 1.52091
5 5T9F NAP 0.003982 0.40731 1.52091
6 3A4T SFG 0.006743 0.40571 1.52091
7 1J5P NAD 0.004221 0.40018 1.58103
8 2GZ3 NAP 0.00032 0.46378 1.90114
9 3CMC NAD 0.002823 0.43641 1.90114
10 4R5M NAP 0.0004512 0.43464 1.90114
11 4R5M 4NO 0.0005409 0.42283 1.90114
12 3H9E NAD 0.002341 0.41291 1.90114
13 1LSS NAD 0.002272 0.42918 2.14286
14 4GLL NAD 0.00000001635 0.61061 2.28137
15 4TQG NDP 0.00000001818 0.60194 2.28137
16 4O1M NAD 0.0000006224 0.54561 2.28137
17 1UXG NAD 0.00002301 0.49812 2.28137
18 4KOA NDP 0.001972 0.44321 2.28137
19 5E8J SAH 0.006007 0.42854 2.28137
20 1KYQ NAD 0.005163 0.42399 2.28137
21 1J0X NAD 0.003096 0.41891 2.28137
22 1YKJ PHB 0.0079 0.41549 2.28137
23 1YKJ FAD 0.0079 0.41549 2.28137
24 5MZI FYK 0.007463 0.4152 2.28137
25 5MZI FAD 0.007189 0.4152 2.28137
26 1NYT NAP 0.003508 0.40876 2.28137
27 2B4R NAD 0.001517 0.40675 2.28137
28 2E5V FAD 0.006549 0.40578 2.28137
29 2GLX NDP 0.0049 0.40571 2.28137
30 4OPC FDA 0.02943 0.40499 2.28137
31 1WP4 NDP 0.003563 0.40303 2.28137
32 2YPI PGA 0.0291 0.40234 2.42915
33 1V6A TRE 0.001548 0.47911 2.6616
34 3BAZ NAP 0.0008714 0.43304 2.6616
35 2A92 NAI 0.0002553 0.42976 2.6616
36 1E5Q NDP 0.000615 0.42952 2.6616
37 1MUU NAD 0.00115 0.4282 2.6616
38 3NJ4 AFX 0.01426 0.42505 2.6616
39 3NJ4 NAD 0.01453 0.42468 2.6616
40 1PZG A3D 0.00008377 0.42375 2.6616
41 1MV8 NAD 0.001082 0.41315 2.6616
42 2IXB NAD 0.001074 0.41289 2.6616
43 1GQ2 NAP 0.001693 0.41276 2.6616
44 2CDC NAP 0.01325 0.40721 2.6616
45 3L9W AMP 0.003445 0.40371 2.6616
46 3GU3 SAH 0.03079 0.40109 2.6616
47 2HMT NAI 0.001352 0.43534 2.77778
48 3QX9 ATP 0.03791 0.40374 2.89855
49 2GDJ ANP 0.01999 0.41063 3.0303
50 1R6D NAD 0.0000004463 0.5856 3.04183
51 1RKX NAD 0.00000002961 0.57752 3.04183
52 1R6D DAU 0.000001235 0.56614 3.04183
53 1D7O NAD 0.0000003705 0.49965 3.04183
54 1EZ4 NAD 0.0001259 0.44751 3.04183
55 1CER NAD 0.000349 0.4455 3.04183
56 3WQQ IB3 0.0009725 0.43709 3.04183
57 4KP7 NAP 0.001846 0.43174 3.04183
58 4N14 WR7 0.006387 0.42806 3.04183
59 4KP7 1UQ 0.001963 0.42689 3.04183
60 2BH9 NAP 0.005463 0.42659 3.04183
61 4DPL NAP 0.0008489 0.41976 3.04183
62 5JY6 NAD 0.004166 0.419 3.04183
63 5DA3 58V 0.01505 0.41688 3.04183
64 4W6Z 8ID 0.002302 0.41668 3.04183
65 5U8U FAD 0.01775 0.4018 3.04183
66 4OOE NDP 0.0004785 0.4401 3.42205
67 4RSL FAD 0.001728 0.42157 3.42205
68 5H81 NAP 0.003353 0.4186 3.42205
69 3B1J NAD 0.001162 0.41493 3.42205
70 1P31 EPU 0.008598 0.41042 3.42205
71 2QRK AMP 0.004611 0.40697 3.42205
72 4EIP K2C 0.008489 0.40384 3.42205
73 4EIP FAD 0.008489 0.40384 3.42205
74 2DT5 NAD 0.0008586 0.424 3.79147
75 1SB8 UD2 0.0000001219 0.60762 3.80228
76 1SB8 NAD 0.0000001651 0.59684 3.80228
77 1WVG APR 0.0000003331 0.57012 3.80228
78 2Q1S NAI 0.000002077 0.54674 3.80228
79 1A5Z NAD 0.00004739 0.49703 3.80228
80 1SOW NAD 0.00003496 0.48201 3.80228
81 1LDN NAD 0.0001069 0.46171 3.80228
82 1I0Z NAI 0.00006197 0.46164 3.80228
83 1H9A NAP 0.0005012 0.4401 3.80228
84 4RDH AMP 0.00594 0.42488 3.80228
85 2JHF NAD 0.04166 0.40761 3.80228
86 1R37 NAD 0.003832 0.40565 3.80228
87 5LD5 NAD 0.001042 0.40552 3.80228
88 3F81 STT 0.006128 0.42393 3.82514
89 1OC2 NAD 0.0000009219 0.42215 4.02299
90 1OC2 TDX 0.0000009219 0.42215 4.02299
91 4U7W NDP 0.00000001691 0.59763 4.18251
92 2X6T NAP 0.0000001509 0.55881 4.18251
93 1GY8 NAD 0.000000112 0.55567 4.18251
94 1EQ2 NAP 0.0000002619 0.54971 4.18251
95 3A4V NAD 0.0000002117 0.51426 4.18251
96 3A4V PYR 0.0000002117 0.51426 4.18251
97 5JAQ NAI 0.00001193 0.51083 4.18251
98 1LTH NAD 0.00001992 0.50338 4.18251
99 2CVQ NDP 0.0005628 0.43098 4.18251
100 3OJO NAD 0.002162 0.4234 4.18251
101 4L8V NAP 0.001253 0.4192 4.18251
102 4GKV NAD 0.000276 0.41903 4.18251
103 2BRY FAD 0.001827 0.41695 4.18251
104 4TXI FAD 0.001764 0.41623 4.18251
105 4CJX NAP 0.001226 0.40843 4.18251
106 5EOW FAD 0.003724 0.40614 4.18251
107 3LKF PC 0.04926 0.40421 4.18251
108 1ZMD NAI 0.005468 0.40102 4.18251
109 2DTJ THR 0.02746 0.40362 4.49438
110 1ORR NAD 0.00000002977 0.60268 4.56274
111 5IN4 6CK 0.000009922 0.58273 4.56274
112 5IN4 NAP 0.00001013 0.58273 4.56274
113 5IN4 GDP 0.00001115 0.57952 4.56274
114 4J1Q NDP 0.0000002364 0.55459 4.56274
115 1ZQ9 SAM 0.002578 0.43401 4.56274
116 1HYH NAD 0.0003212 0.43067 4.56274
117 1SAY PYR 0.001892 0.41762 4.56274
118 1CF2 NAP 0.0007948 0.41668 4.56274
119 5KMS NAD 0.007662 0.41334 4.56274
120 1TB4 PEJ 0.001292 0.41295 4.56274
121 1LLU NAD 0.0005426 0.40993 4.56274
122 3OND ADN 0.006709 0.40885 4.56274
123 1TI7 NAP 0.0006376 0.40721 4.56274
124 2VUT NAD 0.0008379 0.40302 4.56274
125 3KB6 NAD 0.003577 0.40297 4.56274
126 2YVJ NAI 0.01277 0.40266 4.56274
127 5I39 FAD 0.006594 0.4008 4.56274
128 2JE7 XMM 0.03204 0.40792 4.60251
129 1DRV A3D 0.006432 0.40658 4.7619
130 1E7S NAP 0.00000006932 0.58638 4.94297
131 1BXK NAD 0.0000001012 0.57356 4.94297
132 1KEW TYD 0.0000009704 0.56802 4.94297
133 3RFV NAI 0.0000002977 0.56098 4.94297
134 1KEW NAD 0.00000208 0.55564 4.94297
135 4EUE NAI 0.0000005837 0.55065 4.94297
136 3RFV 15L 0.000006914 0.51261 4.94297
137 1T26 NAI 0.0001742 0.46814 4.94297
138 5MDH NAD 0.0002014 0.45138 4.94297
139 4MDH NAD 0.000432 0.43855 4.94297
140 2I3G NAP 0.0003772 0.42789 4.94297
141 3V1Y NAD 0.0009838 0.42776 4.94297
142 5JE8 NAD 0.003629 0.40817 4.94297
143 3S5W FAD 0.00332 0.40299 4.94297
144 2DBZ NAP 0.003151 0.40248 4.94297
145 1RM4 NDP 0.002153 0.40334 5.04451
146 5KKA 6V0 0.0001097 0.46284 5.32319
147 4OHU NAD 0.0000001753 0.43763 5.32319
148 4OHU 2TK 0.0000001753 0.43763 5.32319
149 1HYE NAP 0.0003212 0.42144 5.32319
150 1DSS NAD 0.0006285 0.41911 5.32319
151 4YCA NDP 0.002385 0.41259 5.32319
152 4RQU NAD 0.002248 0.40808 5.32319
153 3I6I NDP 0.0002837 0.40558 5.32319
154 1EK6 NAI 0.0000002 0.60001 5.70342
155 3LU1 NAD 0.00000001607 0.59476 5.70342
156 3KO8 NAD 0.00000001114 0.583 5.70342
157 1EK6 UPG 0.0000005995 0.58265 5.70342
158 3H8V ATP 0.0006247 0.4617 5.70342
159 3L4S NAD 0.002982 0.40742 5.70342
160 3L4S 3PG 0.003294 0.407 5.70342
161 2HK9 NAP 0.002318 0.4017 5.70342
162 1X7D ORN 0.005935 0.40157 5.70342
163 1PN0 IPH 0.01068 0.4014 5.70342
164 1PN0 FAD 0.0102 0.4014 5.70342
165 2BKA NDP 0.0000006221 0.54354 5.78512
166 1HDO NAP 0.00000508 0.48135 5.82524
167 9LDT NAD 0.00003066 0.48256 6.08365
168 1V35 NAI 0.0000008009 0.47119 6.08365
169 9LDB NAD 0.0000273 0.46901 6.08365
170 1LDM NAD 0.0001132 0.45219 6.08365
171 1PL6 572 0.002401 0.41106 6.08365
172 1PL6 NAD 0.0005101 0.40546 6.08365
173 1RSG FAD 0.00679 0.40422 6.08365
174 2FR1 NDP 0.00000001957 0.57568 6.3786
175 4Q9N NAI 0.0000002122 0.56559 6.46388
176 2IZ1 ATR 0.007521 0.4414 6.46388
177 4J36 FAD 0.0008821 0.42922 6.46388
178 4J36 1HR 0.003146 0.41863 6.46388
179 5UAO FAD 0.004479 0.40747 6.46388
180 4BHL ARG 0.03269 0.40267 6.46388
181 1I2B NAD 0.000001907 0.56065 6.68317
182 1I2B USQ 0.00453 0.44923 6.68317
183 1I2B UPG 0.00453 0.44923 6.68317
184 2Q46 NAP 0.000000118 0.57102 6.71937
185 2DC1 NAD 0.001174 0.41605 6.77966
186 1O6Z NAD 0.0003266 0.45378 6.84411
187 1O0S NAI 0.002612 0.41999 6.84411
188 2WPB ZZI 0.02687 0.41202 6.84411
189 1RYI FAD 0.005013 0.40856 6.84411
190 2NAD NAD 0.004816 0.40294 6.84411
191 1X87 NAD 0.001166 0.40216 6.84411
192 3ABI NAD 0.0006229 0.42475 6.84932
193 5LKC FUC GLA A2G 0.01259 0.41756 7.14286
194 4YMZ 13P 0.03614 0.4012 7.17131
195 2C29 NAP 0.000001135 0.45533 7.22433
196 2C29 DQH 0.000003852 0.44097 7.22433
197 2PV7 NAD 0.0003788 0.44076 7.22433
198 1X14 NAD 0.01088 0.40906 7.22433
199 2BTM PGA 0.03574 0.40145 7.53968
200 2PZM NAD 0.000003315 0.53857 7.60456
201 2PZM UDP 0.000003315 0.53857 7.60456
202 4YSX FAD 0.004295 0.41026 7.60456
203 2NU8 COA 0.002801 0.40984 7.60456
204 3ZNN FAD 0.01421 0.4014 7.60456
205 3OA2 NAD 0.002007 0.40995 7.86164
206 2PD4 DCN 0.0000002689 0.56935 7.98479
207 2PD4 NAD 0.0000002834 0.56846 7.98479
208 1HDG NAD 0.002167 0.41716 7.98479
209 1WDK NAD 0.0004529 0.41673 7.98479
210 2G5C NAD 0.001817 0.41302 7.98479
211 2XYQ SAH 0.005065 0.42079 8.19672
212 2F1K NAP 0.0003204 0.44696 8.36502
213 3GGO ENO 0.0008992 0.43845 8.36502
214 3GGO NAI 0.0008992 0.43845 8.36502
215 1E1M FAD 0.003939 0.42243 8.47826
216 1E6E FAD 0.003201 0.41104 8.47826
217 5J6Y GLC 0.03181 0.4099 8.51064
218 5J6Y BGC 0.03181 0.4099 8.51064
219 3GFB NAD 0.001494 0.41767 8.74525
220 2YY7 NAD 0.0000005851 0.54865 8.97436
221 1GUZ NAD 0.0001512 0.45272 9.12547
222 2EXX NAP 0.00004913 0.4466 9.12547
223 1O94 ADP 0.003844 0.41002 9.12547
224 3WLE NAD 0.003591 0.40908 9.12547
225 1V8B NAD 0.006098 0.40002 9.12547
226 1GV0 NAD 0.00007465 0.46607 9.5057
227 1BW9 NAD 0.001976 0.42835 9.5057
228 1C1X NAD 0.001323 0.42268 9.5057
229 3AB4 THR 0.02367 0.4108 9.5057
230 1BXG NAD 0.001824 0.40539 9.5057
231 4C3Y FAD 0.006178 0.40492 9.5057
232 5EZ7 FAD 0.006678 0.4016 9.5057
233 4PIV NDP 0.0000003069 0.55942 10.2662
234 2C5A GDC 0.0000002687 0.43718 10.2662
235 2C5A NAD 0.0000002687 0.43718 10.2662
236 5CAE SIN 0.001721 0.41795 10.2662
237 5CAE COA 0.0005705 0.41691 10.2662
238 1GAD NAD 0.001705 0.40704 10.2662
239 1F8G NAD 0.007737 0.40317 10.2662
240 1HGX 5GP 0.02344 0.41102 10.3825
241 1N7G NDP 0.0000009262 0.58712 10.6464
242 1N7G GDR 0.000001388 0.56749 10.6464
243 2Q1W NAD 0.0000005412 0.52479 10.6464
244 1Y1P NMN AMP PO4 0.000001001 0.50984 10.6464
245 3AD8 FAD 0.01985 0.40031 11.33
246 3AD8 PYC 0.01985 0.40031 11.33
247 4ZRN NAD 0.0000000142 0.56421 11.4068
248 1RPN NDP 0.0000003175 0.50704 11.4068
249 4ZRN UPG 0.000000151 0.45552 11.4068
250 3CIF NAD 0.0006961 0.42747 11.7871
251 3CIF G3H 0.004618 0.40365 11.7871
252 2VHW NAI 0.002338 0.41641 11.9363
253 5DN9 NAD 0.002504 0.41163 12.1673
254 2DKH FAD 0.004071 0.40343 12.1673
255 1NVM NAD 0.002279 0.41322 12.7536
256 1XSE NDP 0.00000000001185 0.75153 12.9278
257 5FJN FAD 0.005526 0.40782 12.9278
258 5FJN BE2 0.006456 0.40782 12.9278
259 4HXY NDP 0.000000001288 0.65081 13.308
260 1P77 ATR 0.005012 0.45078 13.308
261 5UAV TFB 0.001268 0.42685 13.6882
262 5UAV NDP 0.001268 0.42685 13.6882
263 1DXY NAD 0.001962 0.40391 14.0684
264 3QV1 NAD 0.0004888 0.42386 14.6341
265 4JK3 NAD 0.00319 0.40228 14.6718
266 3B1F NAD 0.0001212 0.47975 14.8289
267 4J4H NAI 0.007816 0.4053 15.0579
268 4J4H 1J1 0.007816 0.4053 15.0579
269 3MJE NDP 0.000000000444 0.66599 15.7258
270 3VPH NAD 0.0000374 0.45298 15.8065
271 3VPH OXM 0.0002701 0.41554 15.8065
272 1Z45 NAD 0.00000002151 0.59009 16.73
273 3RJ5 NAD 0.0000000006718 0.58036 17.3228
274 1FK8 NAD 0.000000000000699 0.79785 17.5097
275 3O26 NDP 0.00000000006602 0.69766 17.8707
276 2FZW NAD 0.004638 0.41183 18.2509
277 1OAA OAA 0.00000000002405 0.57976 19.305
278 5L4S 6KX 0.0000000006839 0.6752 19.3916
279 5L4S NAP 0.0000000006839 0.6752 19.3916
280 5L53 NAP 0.0000000001721 0.62702 19.7719
281 4D42 NAP 0.0000003149 0.58806 19.7719
282 4D42 W0I 0.0000003149 0.58806 19.7719
283 3OJF IMJ 0.0000002413 0.58133 19.8444
284 3OJF NDP 0.0000002402 0.57127 19.8444
285 4PVD NDP 0.0000002176 0.54997 20.1521
286 2EV9 NAP 0.001576 0.41813 20.1521
287 2EV9 SKM 0.001576 0.41813 20.1521
288 5M67 ADE 0.006825 0.40938 22.0532
289 5M67 3D1 0.007201 0.40842 22.0532
290 5M67 NAD 0.007254 0.40829 22.0532
291 2DFV NAD 0.0009728 0.41857 24.3346
292 1WMA AB3 0.000000001826 0.66981 24.7148
293 1WMA NDP 0.000000001826 0.66981 24.7148
294 1N5D NDP 0.0000000002755 0.64839 25.0951
295 5MSO NAP 0.00000003804 0.57907 25.4753
296 1UWK NAD 0.0007395 0.44601 25.8555
297 3ORF NAD 0.0000004213 0.54998 27.0916
298 1UDB NAD 0.0000002373 0.44811 27.3764
299 3CH6 311 0.0000000001294 0.74236 28.5171
300 3CH6 NAP 0.0000000001294 0.74236 28.5171
301 3WXB NDP 0.00000000007861 0.66819 29.2776
302 4J7U YTZ 0.0000000002391 0.70346 31.9392
303 4J7U NAP 0.0000000002391 0.70346 31.9392
304 1W8D NAP 0.000000000114 0.71746 32.1192
305 1W73 NAP 0.0000000001825 0.70912 32.1192
306 1Z6Z NAP 0.0000000001382 0.68538 32.3194
307 3ZV6 NAD 0.0000000002182 0.56701 32.3194
308 3ZV6 4HB 0.0000000002442 0.55891 32.3194
309 1A27 NAP 0.000000001533 0.6454 33.0798
310 3HB5 NAP 0.0000000001588 0.53285 33.0798
311 3OIG NAD 0.0000002053 0.56723 33.0827
312 1W6U NAP 0.0000000001531 0.64876 33.1126
313 2BD0 NAP 0.000000000001433 0.71795 33.8403
314 4K26 NDP 0.00000000001453 0.69524 33.8403
315 4K26 SFF 0.0000000001073 0.59014 33.8403
316 1ZBQ NAD 0.00000000024 0.64045 34.2205
317 1GZ6 NAI 0.000000001603 0.62116 35.3612
318 2GDZ NAD 0.000000000005163 0.74 36.1217
319 1H5Q NAP 0.000000000002867 0.72041 37.3585
320 1QG6 NAD 0.0000002326 0.58504 37.5479
321 1QG6 TCL 0.0000002326 0.58504 37.5479
322 5CG1 NAD BBN 0.0000004037 0.5954 37.6426
323 2DKN NAI 0.000000000001001 0.76409 39.6078
324 2VZ0 NAP 0.000000002265 0.70526 39.924
325 2VZ0 D64 0.000000002265 0.70526 39.924
326 2WD7 NAP 0.0000000001209 0.68483 39.924
327 4CM9 NAP 0.00000000003297 0.70919 40.3042
328 4CME NAP 0.00000000005979 0.69647 40.3042
329 4CLO NAP 0.00000000004627 0.69293 40.3042
330 3JQA NAP 0.0000000001267 0.69153 40.3042
331 4CM4 NAP 0.0000000000812 0.69141 40.3042
332 4CM8 NAP 0.00000000008276 0.69109 40.3042
333 3JQ9 NAP 0.0000000001009 0.69061 40.3042
334 3BMN NAP 0.00000000004305 0.69004 40.3042
335 4CLR NAP 0.00000000009583 0.68867 40.3042
336 3BMO NAP 0.0000000001026 0.68753 40.3042
337 3BMQ NAP 0.00000000005092 0.68741 40.3042
338 3JQ8 NAP 0.00000000005167 0.68717 40.3042
339 3JQF NAP 0.00000000005822 0.68531 40.3042
340 3JQ7 NAP 0.000000000201 0.68376 40.3042
341 4CMI NAP 0.0000000001299 0.68363 40.3042
342 3JQG NAP 0.0000000002411 0.6807 40.3042
343 3JQB NAP 0.0000000002658 0.67906 40.3042
344 3RKR NAP 0.00000003673 0.69894 40.458
345 2DTX BMA 0.000000000003743 0.76917 40.6844
346 4FC7 COA 0.0000000002291 0.70421 40.6844
347 4FC7 NAP 0.0000000002291 0.70421 40.6844
348 1YXM ADE 0.002086 0.45646 41.8251
349 3AFN NAP 0.0000000000004301 0.79043 41.8605
350 3AI3 SOL 0.01026 0.43429 42.2053
351 1E3W NAD 0.000000000003652 0.7291 43.295
352 2WSB NAD 0.00000000006897 0.72103 43.3071
353 1E6W NAD 0.000000000005845 0.72137 43.4615
354 1U7T NAD 0.00000000000624 0.74216 43.6782
355 1U7T TDT 0.00000000002528 0.59275 43.6782
356 2WYV NAD 0.0000003423 0.54626 43.6782
357 1X1T NAD 0.0000000000001585 0.738 44.6154
358 1VL8 NAP 0.000000000003077 0.69576 44.8669
359 1O5I NAD 0.00000005348 0.53388 44.9799
360 3V1U NAD 0.000000000004532 0.71182 45.2471
361 3H4V DVP 0.0000000000613 0.72719 45.6274
362 3H4V NAP 0.0000000002401 0.70143 45.6274
363 5ITV NAI 0.000000000001222 0.767 45.8824
364 2CFC NAD 0.000000000007229 0.7314 46
365 2RH4 EMO 0.000000000002215 0.59082 46.0076
366 3VZS NAP 0.0000000002038 0.54979 46.3035
367 3VZS CAA 0.000000002143 0.44622 46.3035
368 1PR9 NAP 0.0000000000001837 0.80475 46.3115
369 3D3W NAP 0.0000000000004229 0.79071 46.3115
370 3O03 NAP 0.0000000000203 0.69769 46.3878
371 4QED NAP 0.00000000005827 0.69973 46.7742
372 1NFQ NAI 0.000000000002832 0.75586 46.9231
373 1UZN NAP 0.00000006657 0.50038 47.3684
374 4ZA2 NAD 0.00000000001235 0.72255 47.4308
375 1AE1 NAP 0.0000000000001147 0.81269 47.5285
376 2Q2V NAD 0.00000000000005351 0.82553 47.8431
377 2B4Q NAP 0.00000000001454 0.70717 47.9087
378 3AY6 NAI 0.000000000004124 0.64729 47.9087
379 3AY6 BGC 0.0000000000265 0.53808 47.9087
380 2AE2 PTO 0.0000000000000645 0.8418 48.0769
381 2AE2 NAP 0.0000000000000645 0.8418 48.0769
382 1XHL NDP 0.000000000001567 0.76579 49.0494
383 1XKQ NDP 0.000000000001264 0.70757 49.4297
384 1Q7B NAP 0.000000000007786 0.71686 49.5902
385 1ZK4 NAP 0.000000000003641 0.76236 49.8008
386 1ZK4 AC0 0.000111 0.53836 49.8008
387 1GEG NAD 0.00000000000492 0.72415 50
Feedback