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Receptor
PDB id Resolution Class Description Source Keywords
4OPI 2.24 Å EC: 1.3.1.83 CONSTRUCTING TAILORED ISOPRENOID PRODUCTS BY STRUCTURE-GUIDE MODIFICATION OF GERANYLGERANYL REDUCTASE. SULFOLOBUS ACIDOCALDARIUS ROSSMANN FOLD OXIDOREDUCTASE ARCHAEAL PROTEIN
Ref.: CONSTRUCTING TAILORED ISOPRENOID PRODUCTS BY STRUCTURE-GUIDED MODIFICATION OF GERANYLGERANYL RED STRUCTURE V. 22 1028 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GRG A:503;
A:502;
Valid;
Valid;
none;
none;
submit data
450.443 C20 H36 O7 P2 CC(=C...
FDA A:501;
Valid;
none;
submit data
787.566 C27 H35 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4OPC 1.4 Å EC: 1.3.1.83 CONSTRUCTING TAILORED ISOPRENOID PRODUCTS BY STRUCTURE-GUIDE MODIFICATION OF GERANYLGERANYL REDUCTASE. SULFOLOBUS ACIDOCALDARIUS ROSSMANN FOLD OXIDOREDUCTASE ARCHAEAL PROTEIN
Ref.: CONSTRUCTING TAILORED ISOPRENOID PRODUCTS BY STRUCTURE-GUIDED MODIFICATION OF GERANYLGERANYL RED STRUCTURE V. 22 1028 2014
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4OPI - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
2 4OPG - GRG C20 H36 O7 P2 CC(=CCC/C(....
3 4OPD - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
4 4OPC - PGT C40 H79 O10 P CCCCCCCCCC....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4OPI - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
2 4OPG - GRG C20 H36 O7 P2 CC(=CCC/C(....
3 4OPD - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
4 4OPC - PGT C40 H79 O10 P CCCCCCCCCC....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4OPI - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
2 4OPG - GRG C20 H36 O7 P2 CC(=CCC/C(....
3 4OPD - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
4 4OPC - PGT C40 H79 O10 P CCCCCCCCCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GRG; Similar ligands found: 35
No: Ligand ECFP6 Tc MDL keys Tc
1 OTP 1 0.975
2 GRG 1 1
3 ZTP 1 0.975
4 FPP 1 1
5 VTP 1 0.975
6 GPP 0.911111 0.974359
7 DSL 0.744681 0.9
8 FJP 0.744681 0.923077
9 0K3 0.744681 0.9
10 FDF 0.727273 0.904762
11 FFF 0.714286 0.928571
12 FGG 0.590164 0.928571
13 2CF 0.57377 0.928571
14 FPF 0.57377 0.928571
15 10D 0.568627 0.785714
16 10E 0.568627 0.702128
17 MGM 0.5625 0.764706
18 DMA 0.5625 0.846154
19 A4S 0.558824 0.698113
20 3E9 0.555556 0.951219
21 FPS 0.551724 0.880952
22 GGS 0.551724 0.880952
23 H6P 0.54902 0.785714
24 FPQ 0.539683 0.826087
25 10G 0.538462 0.767442
26 FII 0.507937 0.666667
27 GST 0.482759 0.857143
28 PS7 0.48 0.906977
29 FHP 0.473684 0.761905
30 1NH 0.457831 0.770833
31 0FV 0.442623 0.904762
32 LA6 0.442623 0.904762
33 749 0.428571 0.897436
34 SZH 0.428571 0.655172
35 9GB 0.415094 0.825
Ligand no: 2; Ligand: FDA; Similar ligands found: 141
No: Ligand ECFP6 Tc MDL keys Tc
1 FDA 1 1
2 FNK 0.691781 0.965517
3 F2N 0.647436 0.976744
4 FAS 0.641892 0.906977
5 FAD 0.641892 0.906977
6 SFD 0.630872 0.787879
7 6FA 0.61745 0.896552
8 6YU 0.586207 0.903226
9 RFL 0.585987 0.876405
10 FAD NBT 0.584906 0.902174
11 FAY 0.579618 0.895349
12 62F 0.573248 0.895349
13 FA9 0.554217 0.918605
14 FAD CNX 0.551515 0.873684
15 P5F 0.545455 0.920455
16 FNR 0.532258 0.892857
17 FAD NBA 0.526012 0.873684
18 A2D 0.516667 0.833333
19 AR6 0.5 0.811765
20 APR 0.5 0.811765
21 M33 0.496 0.823529
22 BA3 0.495935 0.833333
23 P6G FDA 0.494186 0.827957
24 B4P 0.491935 0.833333
25 AP5 0.491935 0.833333
26 ANP 0.488372 0.813953
27 AGS 0.484375 0.795455
28 SAP 0.484375 0.795455
29 HEJ 0.480315 0.833333
30 ATP 0.480315 0.833333
31 ADP 0.48 0.833333
32 48N 0.479167 0.818182
33 FB0 0.478261 0.819149
34 AQP 0.476562 0.833333
35 5FA 0.476562 0.833333
36 AT4 0.47619 0.804598
37 AN2 0.47619 0.823529
38 GTA 0.475524 0.831461
39 AD9 0.472868 0.813953
40 3OD 0.471014 0.835294
41 FAE 0.46988 0.896552
42 ATF 0.469697 0.804598
43 AP0 0.469388 0.860465
44 ACP 0.46875 0.835294
45 OAD 0.467153 0.835294
46 9X8 0.467153 0.795455
47 PAJ 0.463235 0.808989
48 A1R 0.463235 0.827586
49 A3R 0.463235 0.827586
50 G3A 0.461538 0.83908
51 T5A 0.46 0.896552
52 A22 0.459259 0.845238
53 G5P 0.458333 0.83908
54 6YZ 0.455224 0.835294
55 DQV 0.455172 0.845238
56 ACQ 0.454545 0.835294
57 PRX 0.453846 0.793103
58 5AL 0.451128 0.823529
59 ADX 0.449612 0.741935
60 CA0 0.449612 0.813953
61 50T 0.446154 0.802326
62 8QN 0.445255 0.823529
63 ABM 0.444444 0.790698
64 A 0.443548 0.809524
65 AMP 0.443548 0.809524
66 TXE 0.442953 0.892857
67 OMR 0.442953 0.782609
68 ADQ 0.442029 0.813953
69 AMO 0.442029 0.825581
70 ADJ 0.440789 0.822222
71 139 0.440789 0.862069
72 B5M 0.440559 0.837209
73 BIS 0.439716 0.786517
74 PTJ 0.439716 0.818182
75 ME8 0.439716 0.771739
76 TXA 0.439716 0.825581
77 AFH 0.438356 0.788889
78 A4P 0.437086 0.876405
79 6V0 0.436242 0.882353
80 UP5 0.436242 0.880952
81 TXD 0.436242 0.870588
82 DND 0.436242 0.825581
83 NXX 0.436242 0.825581
84 5SV 0.434783 0.758242
85 SRP 0.433824 0.804598
86 4AD 0.431655 0.816092
87 B5Y 0.430556 0.837209
88 P1H 0.430303 0.842697
89 FYA 0.429577 0.823529
90 AHX 0.428571 0.797753
91 SRA 0.428571 0.772727
92 P33 FDA 0.427778 0.821053
93 MAP 0.427536 0.795455
94 AU1 0.427481 0.813953
95 NAI 0.426667 0.870588
96 25L 0.426573 0.845238
97 AP2 0.426357 0.825581
98 A12 0.426357 0.825581
99 CNV FAD 0.426136 0.876405
100 EAD 0.423313 0.862069
101 COD 0.423077 0.806452
102 PR8 0.422535 0.8
103 T99 0.422222 0.804598
104 TAT 0.422222 0.804598
105 APC 0.421053 0.825581
106 4TC 0.421053 0.882353
107 NB8 0.41958 0.797753
108 1ZZ 0.41958 0.771739
109 4UU 0.418919 0.837209
110 GA7 0.418919 0.825581
111 00A 0.41844 0.786517
112 ADV 0.41791 0.804598
113 RBY 0.41791 0.804598
114 A3D 0.417722 0.835294
115 NAX 0.417219 0.862069
116 OOB 0.414286 0.823529
117 25A 0.414286 0.833333
118 LAD 0.412587 0.788889
119 UPA 0.411765 0.870588
120 CNA 0.410256 0.825581
121 80F 0.408805 0.833333
122 DLL 0.408451 0.823529
123 XAH 0.408163 0.771739
124 4UW 0.407895 0.829545
125 F2R 0.407643 0.793478
126 ADP PO3 0.407407 0.788235
127 DAL AMP 0.407143 0.802326
128 3UK 0.405594 0.835294
129 4UV 0.405405 0.837209
130 TYM 0.405229 0.825581
131 NAD 0.405063 0.823529
132 9ZD 0.404255 0.827586
133 9ZA 0.404255 0.827586
134 9SN 0.40411 0.797753
135 VO4 ADP 0.402878 0.781609
136 ADP VO4 0.402878 0.781609
137 WAQ 0.402778 0.806818
138 B5V 0.402778 0.825581
139 YAP 0.401361 0.816092
140 FA5 0.401361 0.825581
141 YLP 0.401316 0.793478
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4OPC; Ligand: FDA; Similar sites found with APoc: 1165
This union binding pocket(no: 1) in the query (biounit: 4opc.bio1) has 89 residues
No: Leader PDB Ligand Sequence Similarity
1 4TM3 FAD 1.12867
2 2WA4 069 1.14613
3 4DPL NAP 1.39276
4 6BMS PLM 1.46628
5 2FB3 GTP 1.47059
6 1CF2 NAP 1.48368
7 1KOL NAD 1.50754
8 1H5Q NAP 1.50943
9 1GAD NAD 1.51515
10 1YKJ FAD 1.52284
11 1YKJ PHB 1.52284
12 3TDC 0EU 1.54525
13 4WOE ADP 1.54525
14 1GZ4 ATP 1.54525
15 3PT9 SAH 1.54525
16 5DXT 5H5 1.54525
17 1U8X NAD 1.54525
18 5E4R NAP 1.54525
19 3C1O NAP 1.55763
20 3DMH SAM 1.5748
21 3DMH GMP 1.5748
22 4R5M NAP 1.59574
23 1SQF SAM 1.6317
24 1KEV NDP 1.7094
25 5YU3 PRO 1.74419
26 5YU3 NAD 1.74419
27 1WG8 SAM 1.75439
28 2BRY FAD 1.766
29 5JWC FAD 1.766
30 6CFC BLG 1.766
31 4KCT PYR 1.766
32 4XQC NAD 1.766
33 4XQC 13D 1.766
34 2QRK AMP 1.77665
35 3V1Y NAD 1.78042
36 3SJU NDP 1.79211
37 1J0X NAD 1.80723
38 4E5N NAD 1.81818
39 3SIX GDP 1.81818
40 2EJU SAH 1.85185
41 5F8F SFG 1.85676
42 4DCM SAM 1.86667
43 1DL5 SAH 1.89274
44 1TDF FAD 1.89873
45 1TDF NAP 1.89873
46 1HYH NAD 1.94175
47 1WVG APR 1.94986
48 1GEG NAD 1.95312
49 1YJQ NAP 1.9802
50 4OOE FOM 1.9802
51 4OOE NDP 1.9802
52 1OLM VTQ 1.98511
53 1X87 NAD 1.98676
54 5GSN FAD 1.98676
55 5GSN MMZ 1.98676
56 1P31 EPU 1.98676
57 5GSN NAP 1.98676
58 1QMG APX 1.98676
59 5U97 PIT 1.98676
60 1P3D UMA 1.98676
61 5JSD ACY 1GN GAL 1GN BGC ACY GAL BGC 1.98676
62 5M67 ADE 1.98676
63 5M67 NAD 1.98676
64 3OND ADN 1.98676
65 3OND NAD 1.98676
66 5M67 3D1 1.98676
67 1YKF NAP 1.98864
68 4Q9N NAI 2.01342
69 1XHL NDP 2.0202
70 5ZI2 ADP 2.02899
71 5ZI2 NAD 2.02899
72 4XDZ NDP 2.04082
73 5A1T NAI 2.05279
74 5A1T OXM 2.05279
75 5H81 NAP 2.05656
76 4I5I NAD 2.09059
77 5G4L NDP 2.0979
78 1V6A TRE 2.10843
79 9LDT NAD 2.10843
80 9LDB NAD 2.10843
81 3GU3 SAH 2.11268
82 1NJR XYL 2.11268
83 2GCG NDP 2.12121
84 6BWL NAD 2.13415
85 1XG5 NAP 2.15054
86 5T67 SAH 2.16346
87 1T26 NAI 2.17391
88 1T26 GBD 2.17391
89 2A92 NAI 2.18069
90 1QIN GIP 2.18579
91 1N1G BCP 2.18579
92 3WUD GLC GAL 2.20588
93 3V1U NAD 2.20751
94 3ULK NDP 2.20751
95 3HQP OXL 2.20751
96 3K5I AIR 2.23325
97 2GSD NAD 2.23881
98 1PL6 NAD 2.24719
99 1BW9 NAD 2.24719
100 1BXG NAD 2.24719
101 1PL6 572 2.24719
102 2EV1 OLA 2.25225
103 1C1X NAD 2.25352
104 4OSP NAP 2.28137
105 3GFB NAD 2.28571
106 2NAD NAD 2.29008
107 4QAC KK3 2.30415
108 2DFV NAD 2.30548
109 1O6Z NAD 2.31023
110 1Q0S SAH 2.3166
111 1LFO OLA 2.34375
112 1Z3C SA8 2.34899
113 2E3N 6CM 2.35294
114 3C6K SPD 2.3622
115 3C6K MTA 2.3622
116 3WV6 GAL BGC 2.36486
117 2D2I NAP 2.36842
118 5AHO TLA 2.38095
119 1D1T NAD 2.41287
120 4OR7 25U 2.42424
121 2QA1 FAD 2.42826
122 2JHP SAH 2.42826
123 3PQB VGP 2.42826
124 3FW9 SLX 2.42826
125 1VKO NAD 2.42826
126 2YIC TPP 2.42826
127 2VDV SAM 2.43902
128 2CDC NAP 2.45902
129 2CDC XYP 2.45902
130 2CDC XYS 2.45902
131 4A0S NAP 2.46085
132 1NV8 MEQ 2.46479
133 1NV8 SAM 2.46479
134 2DPM SAM 2.46479
135 2VTD LKM 2.47191
136 5H5A 6OU 2.5
137 1H2B NAJ 2.50696
138 4FZV SAM 2.51046
139 2XVM SAH 2.51256
140 4KIB SAH 2.52101
141 1GQG DCD 2.57143
142 5C3R HMU 2.62391
143 5C3R AKG 2.62391
144 2O07 MTA 2.63158
145 1U6R ADP 2.63158
146 2O07 SPD 2.63158
147 4L3L 5FI 2.63158
148 1UP7 NAD 2.63789
149 1TSD UMP 2.64151
150 5Z2F NAP 2.64151
151 1PJS NAD 2.64901
152 1YY5 FAD 2.64901
153 1RSG FAD 2.64901
154 1FEC FAD 2.64901
155 2XVF FAD 2.64901
156 4AT0 FAD 2.64901
157 3Q3C NAD 2.64901
158 4J1Q NDP 2.64901
159 1DGH NDP 2.64901
160 2ZJ1 ARJ 2.64901
161 2ZJ1 NAD 2.64901
162 4NEC SAH 2.65152
163 1RJW ETF 2.65487
164 3B20 NAD 2.65487
165 3B1J NAD 2.65487
166 3L9W AMP 2.66344
167 3L9W GSH 2.66344
168 4RQU NAD 2.66667
169 1RM4 NDP 2.67062
170 4M73 SAH 2.67062
171 4M73 M72 2.67062
172 4Z0H NAD 2.69461
173 4PLG NAI 2.69461
174 4PLG OXM 2.69461
175 1VDC FAD 2.7027
176 1J49 NAD 2.7027
177 5Y8L NAD 2.71186
178 5Y8L HUI 2.71186
179 2PWY SAH 2.71318
180 4PLT NAI 2.71903
181 4PLT OXM 2.71903
182 4HXY NDP 2.73973
183 1VL0 NAI 2.73973
184 1WP4 NDP 2.76817
185 2BJ4 OHT 2.77778
186 3JQA NAP 2.77778
187 5JDI NAP 2.77778
188 3BMQ NAP 2.77778
189 5JCJ NAP 2.77778
190 4CM8 NAP 2.77778
191 3JQ9 NAP 2.77778
192 3BMO NAP 2.77778
193 5K6A NAP 2.77778
194 3JQF NAP 2.77778
195 5JDC NAP 2.77778
196 3BMN NAP 2.77778
197 3JQB NAP 2.77778
198 4CM4 NAP 2.77778
199 4CMI NAP 2.77778
200 4CLR NAP 2.77778
201 4CM9 NAP 2.77778
202 3JQG NAP 2.77778
203 3JQ8 NAP 2.77778
204 4CME NAP 2.77778
205 4CLO NAP 2.77778
206 3JQ7 NAP 2.77778
207 5K4W NAI 2.80374
208 5K4W THR 2.80374
209 1ZQ9 SAM 2.80702
210 4RVG SAM 2.8169
211 4RVG TYD 2.8169
212 6F3M NAD 2.82609
213 2FK8 SAM 2.83019
214 1EDO NAP 2.86885
215 5MQ6 NDP 2.86976
216 3CGD NAD 2.86976
217 4B63 ORN 2.86976
218 4B63 FAD 2.86976
219 4B63 NAP 2.86976
220 5WP4 SAH 2.86976
221 2ZTG A5A 2.86976
222 3CGD COA 2.86976
223 3CGD FAD 2.86976
224 6D6Y SAH 2.86976
225 3FP0 FP0 2.86976
226 3ETG NDP 2.86976
227 3ETG GLU 2.86976
228 2HZQ STR 2.87356
229 3H7J PPY 2.88066
230 4W6Z 8ID 2.88184
231 5EO8 TFU 2.89389
232 1DJL NAP 2.89855
233 2YG2 S1P 2.90698
234 5EIN NAP 2.90698
235 2YG2 FLC 2.90698
236 5EY0 GTP 2.91971
237 1AE1 NAP 2.9304
238 4YT4 FE9 2.93333
239 3FUU ADN 2.95203
240 5T9E NAP 2.95203
241 4RFR RHN 2.95567
242 4QTU SAM 2.96296
243 5XNC MTA 2.96496
244 5MGZ SAH 2.9661
245 1SC6 NAD 2.9703
246 5JE8 NAD 2.98013
247 2WD7 NAP 2.98507
248 1VL8 NAP 2.99625
249 1JQ3 AAT 3.04054
250 5GT9 NAP 3.04183
251 3GRU AMP 3.05085
252 1EBF NAD 3.07263
253 5LD5 NAD 3.07263
254 5FI3 NAP 3.08123
255 5WGR FAD 3.09051
256 3NTD FAD 3.09051
257 3NTA FAD 3.09051
258 3NT6 FAD 3.09051
259 5DNK SAH 3.09051
260 5OC1 FAD 3.09051
261 2C7G ODP 3.09051
262 2C7G FAD 3.09051
263 2CFM AMP 3.09051
264 3SSO SAH 3.10263
265 2VPQ ANP 3.10421
266 5UAV NDP 3.10559
267 5UAV TFB 3.10559
268 1E5Q NDP 3.11111
269 6ECT SAM 3.11526
270 5KVS NAP 3.11688
271 5UR0 NAD 3.15186
272 6DUB SAH 3.15315
273 1MJT ITU 3.17003
274 3MF2 AMP 3.17919
275 4TV1 36M 3.18725
276 4NBU NAI 3.2
277 1XDS SAM 3.20856
278 5EOW FAD 3.20988
279 1XKQ NDP 3.21429
280 3MAG SAH 3.25733
281 3UN3 G16 3.25815
282 1D4O NAP 3.26087
283 5FUB SAH 3.2641
284 5FA5 MTA 3.26975
285 2YX1 SFG 3.27381
286 6CEP NAD 3.29341
287 6CEP OXM 3.29341
288 6FDF SAH 3.29341
289 1JAY NAP 3.30189
290 3A27 SAM 3.30882
291 6F9Q NAD 3.30882
292 2DKH FAD 3.31126
293 2DKH 3HB 3.31126
294 4KRG SAH 3.31126
295 4PIV NDP 3.31126
296 4EDF UPG 3.31126
297 1ULE GLA GAL NAG 3.33333
298 4EUE NAI 3.34928
299 5UFN SAH 3.36134
300 3MCT SAH 3.367
301 4QCK ASD 3.36788
302 5MPT SAH 3.38164
303 3W68 VIV 3.38346
304 3LCC SAH 3.40426
305 4L2I FAD 3.42205
306 2PK3 A2R 3.42679
307 3O03 NAP 3.43643
308 3H2B SAH 3.44828
309 1IXE CIT 3.44828
310 4YAG NAI 3.46021
311 4QM9 CYS 3.46821
312 3A4V PYR 3.47003
313 3A4V NAD 3.47003
314 3VQ2 LP4 LP5 MYR DAO 3.47222
315 2AHR NAP 3.4749
316 1DLJ NAI 3.48259
317 1DLJ UGA 3.48259
318 4OAR 2S0 3.48837
319 4GQB 0XU 3.48837
320 3QJ4 FAD 3.50877
321 5GLT BGC GAL NAG GAL 3.52113
322 5E9W SAH 3.52564
323 3MB5 SAM 3.52941
324 1ZH8 NAP 3.52941
325 5W3K NDP 3.52941
326 5W3K 9TY 3.52941
327 3ICT ADP 3.53201
328 3ICS ADP 3.53201
329 3ICT FAD 3.53201
330 3ICR FAD 3.53201
331 3ICS FAD 3.53201
332 5VN0 FAD 3.53201
333 1VQW FAD 3.53201
334 2IZ1 ATR 3.53201
335 1O0S NAI 3.53201
336 5VN0 NAI 3.53201
337 1I1E DM2 3.53201
338 1V8B NAD 3.53201
339 1Z45 NAD 3.53201
340 3RGA LSB 3.53357
341 4K5S FAD 3.54478
342 4K5S PM0 3.54478
343 6FOF LAT 3.57143
344 4GKV NAD 3.57143
345 2GVC FAD 3.57942
346 2GV8 FAD 3.57942
347 2GV8 NDP 3.57942
348 4BVA NDP 3.58209
349 1Z82 NDP 3.58209
350 5CJF 520 3.58423
351 1DIG NAP 3.59477
352 4Y9D NAI 3.60656
353 3GMB FAD 3.61446
354 1HDG NAD 3.61446
355 1O5I NAD 3.61446
356 5ODY 9SK 3.62319
357 5HIP 61O 3.63036
358 1W8D NAP 3.64238
359 1W73 NAP 3.64238
360 1M2W NAD 3.65112
361 1DRV A3D 3.663
362 3DXY SAM 3.66972
363 4RF2 NAP 3.67647
364 2RGH FAD 3.67776
365 5GZ6 NDP 3.68098
366 5GZ6 7C3 3.68098
367 3FPF MTA 3.69128
368 3FPF TNA 3.69128
369 2I3G NAP 3.69318
370 3QWI NAP 3.7037
371 2PXX SAH 3.72093
372 4D7E FAD 3.7296
373 4TXI FAD 3.75276
374 2F5Z FAD 3.75276
375 4BV6 FAD 3.75276
376 3GD4 FAD 3.75276
377 5J7X FAD 3.75276
378 3QVP FAD 3.75276
379 3GD4 NAD 3.75276
380 5J5Z FAD 3.75276
381 1GQ2 NAP 3.75276
382 6CB2 OLC 3.75427
383 1Y8Q ATP 3.75723
384 1C3X 8IG 3.7594
385 4EBZ NAG NAG NAG NAG 3.77358
386 2GQS ADP 3.79747
387 2GQR ADP 3.79747
388 4LWP SAH 3.80435
389 4DMG SAM 3.81679
390 1QCI ADE 3.81679
391 1U1I NAD 3.82653
392 1U7T NAD 3.83142
393 1U7T TDT 3.83142
394 1NVM NAD 3.84615
395 4XDY NAI 3.84615
396 5W7K SAH 3.84615
397 1G60 SAM 3.84615
398 5W7M SAH 3.84615
399 3O9Z AKG 3.84615
400 3O9Z NAD 3.84615
401 1Q9I TEO 3.85289
402 1Q9I FAD 3.85289
403 5LX9 OLB 3.87324
404 5GWX SAR 3.87324
405 5GWX SAM 3.87324
406 5N2I NAP 3.87931
407 3AYI FAD 3.8835
408 3AYI HCI 3.8835
409 4OBW SAM 3.89105
410 5FFF NAP 3.89105
411 1MV8 NAD 3.89908
412 1MUU NAD 3.89908
413 3CIF NAD 3.89972
414 3CIF G3H 3.89972
415 1ZB6 DIN 3.90879
416 1ZB6 GST 3.90879
417 5NUF NAD 3.91566
418 5NUE NAD 3.91566
419 6A0S HSE 3.91566
420 6A0S NDP 3.91566
421 5NA1 FAD 3.92157
422 1Q0H FOM 3.94089
423 1Q0H NDP 3.94089
424 5U5N NAD 3.94265
425 1Q1R FAD 3.94432
426 2O4C NAD 3.94737
427 1VM6 NAD 3.94737
428 5L4L NAP 3.94737
429 1J5P NAD 3.95257
430 5HXI FAD 3.95778
431 5HXI 5HN 3.95778
432 5A3B APR 3.9604
433 3SJ7 NDP 3.96825
434 1DJN ADP 3.97351
435 1O94 ADP 3.97351
436 5UAO FAD 3.97351
437 2Q28 ADP 3.97351
438 2VQ5 HBA 3.9801
439 5N5D SAM 3.9823
440 5N6C NAD 4
441 5ZW3 SAH 4
442 6GR0 F8W 4.02299
443 1NYT NAP 4.05904
444 6F7L FAD 4.0724
445 1C3V NDP 4.08163
446 1JIF CU BLM 4.09836
447 5YJS SAL 4.10256
448 5EVY FAD 4.10959
449 2AOT SAH 4.10959
450 1JQD HSM 4.10959
451 1JQD SAH 4.10959
452 4EMI FAD 4.14634
453 4EMI NAD 4.14634
454 3OJO NAD 4.17633
455 1NVT NAP 4.18118
456 3SQP FAD 4.1841
457 5X62 SAH 4.18719
458 1H82 FAD 4.19426
459 1H82 GZZ 4.19426
460 2FR1 NDP 4.19426
461 3UCL CYH 4.19426
462 3UCL FAD 4.19426
463 1UWK URO 4.19426
464 1UWK NAD 4.19426
465 3UCL NAP 4.19426
466 1J3R 6PG 4.21053
467 5JCM FAD 4.21286
468 5JCM NAD 4.21286
469 5JCM ISD 4.21286
470 1GET FAD 4.22222
471 1GET NAP 4.22222
472 1PZG A3D 4.22961
473 1YS4 NAP 4.23729
474 1X14 NAD 4.2394
475 1JG3 ADN 4.25532
476 2GC0 PAN 4.25532
477 1XCL SAH 4.25532
478 5Z75 NAD 4.28135
479 3SI2 PBD 4.28135
480 5GWT NAD 4.31655
481 1R37 NAD 4.32277
482 3NV3 GAL NAG MAN 4.34783
483 1XHC FAD 4.35967
484 2BCG GER 4.36893
485 1LLU NAD 4.38596
486 2V6G NAP 4.3956
487 2D6M LBT 4.40252
488 2BWA GLC BGC 4.40529
489 1V59 NAD 4.41501
490 1KNR FAD 4.41501
491 1V59 FAD 4.41501
492 1BZL FAD 4.41501
493 5KOX FAD 4.41501
494 5KOX RFP 4.41501
495 1GPE FAD 4.41501
496 1NAA 6FA 4.41501
497 3X0D SAH 4.41501
498 4DSG FAD 4.41501
499 4DSG UDP 4.41501
500 1NAA ABL 4.41501
501 5WP5 SAH 4.41501
502 1MO9 FAD 4.41501
503 1BZL GCG 4.41501
504 1MO9 KPC 4.41501
505 5A96 GTP 4.41767
506 5A04 NDP 4.42478
507 5A04 BGC 4.42478
508 2PRG BRL 4.42804
509 3E85 BSU 4.43038
510 1SAY PYR 4.43213
511 5UWA 8ND 4.4335
512 2UW1 GVM 4.43787
513 1TIQ COA 4.44444
514 6C4N NAP 4.45434
515 2VOH CIT 4.4586
516 3L4S NAD 4.46429
517 3L4S 3PG 4.46429
518 3WMX NAD 4.46927
519 1A78 TDG 4.47761
520 1FWV SGA MAG FUC 4.47761
521 3G5S FAD 4.51467
522 2Y6Q FAD 4.52261
523 2Y6Q I7T 4.52261
524 4EA7 JB2 4.54545
525 4EA7 COA 4.54545
526 4YLZ LAT NAG GAL 4.57516
527 4YMH SAH 4.58333
528 3WGT QSC 4.61095
529 3WGT FAD 4.61095
530 3ZNN FAD 4.61095
531 3ZNN 4WL 4.61095
532 4B4U NAP 4.62046
533 6A3J NAI 4.63415
534 6A3J SOE 4.63415
535 5BRT FAD 4.63576
536 1QO8 FAD 4.63576
537 5BRT CH9 4.63576
538 2RAB FAD 4.63576
539 5TS5 FAD 4.63576
540 1REO FAD 4.63576
541 3LAD FAD 4.63576
542 4MIG G3F 4.63576
543 5EB4 FAD 4.63576
544 4MOP 2H5 4.63576
545 3GDN FAD 4.63576
546 2RAB NAD 4.63576
547 3GDN HBX 4.63576
548 5YB7 ORN 4.63576
549 5YB7 FAD 4.63576
550 1GTE FAD 4.63576
551 4TQG NDP 4.64396
552 2VT3 ATP 4.65116
553 2FKA BEF 4.65116
554 5I39 FAD 4.65686
555 2DC1 NAD 4.66102
556 4NBW NAD 4.66926
557 1U0A BGC BGC BGC BGC 4.6729
558 1F06 NDP 4.6875
559 1F06 2NP 4.6875
560 3FG2 FAD 4.70297
561 4YAC NAI 4.7138
562 2RGJ FAD 4.72637
563 1ST0 GTG 4.74777
564 1HKU NAD 4.7486
565 2VHW NAI 4.77454
566 3GGO ENO 4.77707
567 3GGO NAI 4.77707
568 1P77 ATR 4.77941
569 5ZZ6 ADP 4.80769
570 5ZZ6 NAD 4.80769
571 5X20 NAD 4.80769
572 2IVD FAD 4.81172
573 6BQ6 TER 4.83384
574 4KRI SAH 4.84988
575 3T7S SAM 4.85075
576 2ZXI FAD 4.85651
577 2HQM FAD 4.85651
578 3S5W FAD 4.85651
579 4M52 FAD 4.85651
580 2A8X FAD 4.85651
581 3S5W NAP 4.85651
582 4YNU FAD 4.85651
583 4HA6 FAD 4.85651
584 4YNU LGC 4.85651
585 4U8P FDA 4.85651
586 4U8P UDP 4.85651
587 4M52 M52 4.85651
588 4C4A SAH 4.85651
589 4KVL PLM 4.85651
590 6ER9 FAD 4.85651
591 6E1Q CFA 4.85651
592 6ER9 NAP 4.85651
593 6EZ6 C5Z 4.85651
594 1KBI PYR 4.85651
595 1KBI FMN 4.85651
596 2E56 MYR 4.86111
597 5ZBC FAD 4.87805
598 5TUK FAD 4.90196
599 5E72 SAM 4.91329
600 3D3W NAP 4.91803
601 1PR9 NAP 4.91803
602 6DNT NAD 4.94186
603 4M37 SAH 4.95627
604 4M38 SAH 4.95627
605 6AA8 NAD 4.96689
606 6AIN FAD 5.02392
607 5OJL TXP 5.03356
608 3T31 FAD 5.03433
609 3T31 DCQ 5.03433
610 5KOK SAH 5.03778
611 1GY8 NAD 5.03778
612 4LSJ LSJ 5.03876
613 3MQ2 SAH 5.04587
614 1FK8 NAD 5.05837
615 1BXK NAD 5.07042
616 6FP4 FAD 5.07726
617 1ZK7 FAD 5.07726
618 4C3Y FAD 5.07726
619 5MBX FAD 5.07726
620 5MBX SP5 5.07726
621 6FP4 E1T 5.07726
622 1COY FAD 5.07726
623 4C3Y ANB 5.07726
624 5U8U FAD 5.07726
625 3Q9T FAY 5.07726
626 1COY AND 5.07726
627 3UOY NAP 5.07726
628 3UOY FAD 5.07726
629 3K7M FAD 5.10441
630 6C4T NA7 5.11111
631 4FN4 NAD 5.11811
632 4LA7 A1O 5.13595
633 5T9F NAP 5.16605
634 5T9F TYR 5.16605
635 2BZG SAH 5.17241
636 5Y1G NAD 5.18293
637 5DG2 GAL GLC 5.18518
638 2XG5 EC5 5.20231
639 2XG5 EC2 5.20231
640 2DT5 NAD 5.21327
641 5TWB FAD 5.23256
642 1SO2 666 5.2381
643 1DMY AZM 5.24194
644 3NYC FAD 5.24934
645 3NYC IAR 5.24934
646 3B6R ADP 5.24934
647 4REP FAD 5.25253
648 4X9M FAD 5.26316
649 1OMO NAD 5.2795
650 2PT9 S4M 5.29595
651 2PT9 2MH 5.29595
652 2NVK NAP 5.29801
653 2NVK FAD 5.29801
654 4EIP FAD 5.29801
655 4EIP K2C 5.29801
656 1WDK NAD 5.29801
657 4Z24 FAD 5.29801
658 4P42 PEE 5.29801
659 5THQ NDP 5.29801
660 2XVE FAD 5.29801
661 4E13 NAD 5.30035
662 4MP8 MLI 5.30973
663 4MP8 NAD 5.30973
664 2R40 20E 5.32319
665 1QAN SAH 5.32787
666 4BG4 ADP 5.33708
667 2G5C NAD 5.33808
668 3ZJ0 ACO 5.33981
669 5EZ7 FAD 5.35714
670 4ZCC FAD 5.35714
671 4ZCC NAI 5.35714
672 3LTW HLZ 5.35714
673 5ML3 DL3 5.36913
674 5TUF FAD 5.37897
675 5TUF TDC 5.37897
676 2IXB NAD 5.40541
677 2IXB A2G 5.40541
678 5G3U FDA 5.43735
679 5G3U ITW 5.43735
680 1ORR NAD 5.4755
681 5ERG SAM 5.48303
682 3WV8 ATP 5.50459
683 2B4R AES 5.50725
684 2B4R NAD 5.50725
685 1C0I BE2 5.50964
686 1C0I FAD 5.50964
687 3CGB FAD 5.51876
688 6F97 FAD 5.51876
689 2IID PHE 5.51876
690 2IID FAD 5.51876
691 5YAP NAI 5.51876
692 5YAP 8S0 5.51876
693 2CVZ NDP 5.53633
694 4USQ FAD 5.54017
695 2GJ5 VD3 5.55556
696 3ORF NAD 5.57769
697 5ULP KB1 5.59701
698 4EMJ FAD 5.60748
699 1M2K APR 5.62249
700 1W6U NAP 5.62914
701 1NW5 SAM 5.64263
702 3RGG AIR 5.66038
703 3H5N ATP 5.66572
704 3GEG NAD 5.66802
705 2NU8 COA 5.6701
706 1I36 NAP 5.68182
707 4U0W 16G 5.69106
708 2AG8 NAP 5.70342
709 1ZHX HC3 5.70776
710 3KLJ FAD 5.71429
711 1I9G SAM 5.71429
712 4UP3 FAD 5.73248
713 4UP3 NDP 5.73248
714 1HDR NAD 5.7377
715 5Y77 FAD 5.73951
716 2RGO FAD 5.73951
717 3NKS FAD 5.73951
718 4YKG FAD 5.73951
719 4IV9 FAD 5.73951
720 5MZI FAD 5.73951
721 5MZI FYK 5.73951
722 5HSA FAS 5.73951
723 6H3O FAD 5.73951
724 4YKG NAD 5.73951
725 6EL3 NAP 5.77428
726 2R4J FAD 5.78842
727 2R4J 13P 5.78842
728 4YRY FAD 5.7971
729 4YRY NAD 5.7971
730 4U9W COA 5.7971
731 3AXB FAD 5.80357
732 3AXB PRO 5.80357
733 6BHQ NAG NAG FUL BMA MAN MAN NAG GAL 5.80357
734 4USR FAD 5.81717
735 4O0L NDP 5.81818
736 2Q1S NAI 5.83554
737 3VYW SAM 5.84416
738 3A06 NDP 5.85106
739 3A06 FOM 5.85106
740 3DAG FEG 5.86592
741 5YEC ATP 5.88235
742 1KJ8 GAR 5.88235
743 4XYB NDP 5.88235
744 2X6T NAP 5.88235
745 6GNO XDI 5.92593
746 1LTH NAD 5.95611
747 3IHG FAD 5.96026
748 4FWE FAD 5.96026
749 4GUS FAD 5.96026
750 4GUT FAD 5.96026
751 4HSU FAD 5.96026
752 2WET FAD 5.96026
753 2WET TRP 5.96026
754 3LU1 NAD 5.96026
755 4NTC FAD 5.97015
756 1RP0 AHZ 5.98592
757 3RFV 15L 5.99251
758 3RFV NAI 5.99251
759 1X7D NAD 6
760 1X7D ORN 6
761 2GZ3 NAP 6.01093
762 5DX1 SFG 6.01719
763 5DXA SFG 6.01719
764 5DX0 SFG 6.01719
765 5DWQ SFG 6.01719
766 3G2O SAM 6.02007
767 1RYI FAD 6.02094
768 1RYI GOA 6.02094
769 3G89 SAM 6.0241
770 5GP0 GPP 6.04027
771 3HDY FDA 6.04534
772 3HDY FAD 6.04534
773 3HDY GDU 6.04534
774 2JAH NDP 6.07287
775 4ZRN NAD 6.08974
776 1ZEM NAD 6.10687
777 2YVF FAD 6.12745
778 2YVF NAD 6.12745
779 3VPH NAD 6.12903
780 3VPH OXM 6.12903
781 6A5Y 9CR 6.14035
782 5NII FAD 6.14887
783 2Q7V FAD 6.15385
784 5N53 8NB 6.15385
785 2YMZ LAT 6.15385
786 3IA4 MTX 6.17284
787 4JDR FAD 6.18102
788 3X0V FAD 6.18102
789 2ZPA ADP 6.18102
790 2EG5 SAH 6.1828
791 1KYQ NAD 6.20438
792 3U31 NAD 6.2069
793 3TN7 NJP 6.22568
794 3WBF NAP 6.22951
795 3WBF API 6.22951
796 4RDH AMP 6.25
797 4RDI ATP 6.25
798 3SAO DBH 6.25
799 3SAO NKN 6.25
800 1I8T FAD 6.26703
801 5N0J FAD 6.26781
802 4XB2 NDP 6.26866
803 4XB2 HSE 6.26866
804 1GZ6 NAI 6.26959
805 6GAR FAD 6.30372
806 3BAZ NAP 6.30631
807 1N2X SAM 6.31229
808 5DN9 NAD 6.31868
809 5TTJ FAD 6.32653
810 3QH2 3NM 6.33484
811 4D52 GXL 6.34921
812 4D52 GIV 6.34921
813 3H9E NAD 6.35838
814 2PZM NAD 6.36364
815 2PZM UDP 6.36364
816 4CQK PIO 6.38298
817 5DLY SAH 6.39098
818 5AIG VPR 6.4
819 1PS9 FAD 6.40177
820 1PS9 NAP 6.40177
821 4IA6 EIC 6.40177
822 2I7C AAT 6.40177
823 5HA0 LTD 6.41026
824 3AMN CBK 6.41509
825 3AMN CBI 6.41509
826 2YVJ NAI 6.42202
827 2YVJ FAD 6.42202
828 4XUC SAM 6.42202
829 4XUC 43G 6.42202
830 1ELI PYC 6.42674
831 2Q0L FAD 6.43087
832 2Q0L NAP 6.43087
833 6C7D EOJ 6.43275
834 5LOG SAH 6.43777
835 4RYV ZEA 6.45161
836 4URF NAD 6.45161
837 3OFK SAH 6.48148
838 3H8V ATP 6.50685
839 4D79 ATP 6.52174
840 4L8V NAP 6.52819
841 4GLL NAD 6.52819
842 5TPV TYD 6.53595
843 3B1F NAD 6.55172
844 1IM8 SAI 6.55738
845 2FWP CIT 6.55738
846 2FWP ICR 6.55738
847 4JK3 NAD 6.56371
848 5ISY NAD 6.56371
849 4J4H NAI 6.56371
850 4J4H 1J1 6.56371
851 2YW2 ATP 6.60377
852 1DSS NAD 6.60661
853 1E6E FAD 6.62252
854 2Z3Y F2N 6.62252
855 1E1M FAD 6.62252
856 1E1M NAP 6.62252
857 1VJT NAD 6.62252
858 4IP7 FBP 6.62252
859 5X68 FAD 6.64962
860 5K0A FAD 6.66667
861 2BS5 BGC GAL FUC 6.66667
862 1IS3 LAT 6.66667
863 1JNR FAD 6.66667
864 1SOW NAD 6.70732
865 2ZIF SAM 6.73401
866 5EZU MYR 6.74157
867 1IY8 NAD 6.74157
868 3WLE NAD 6.74487
869 4J36 FAD 6.74699
870 4J36 1HR 6.74699
871 4ZU4 4TG 6.75676
872 1EQ2 NAP 6.77419
873 3EGI ADP 6.79612
874 5NMX FAD 6.82353
875 5NMX NAP 6.82353
876 3M3E GAL A2G NPO 6.8323
877 4ZS4 ATP 6.84039
878 3CTY FAD 6.89655
879 1QY1 PRZ 6.89655
880 3BGD SAH 6.92308
881 3BGD PM6 6.92308
882 3HX3 RET 6.96203
883 4POO SAM 7
884 1ZBQ NAD 7.03364
885 3VSE SAH 7.03518
886 1R18 SAH 7.04846
887 3FPZ AHZ 7.05521
888 4NTD FAD 7.05882
889 4EIL UMP 7.06402
890 1YQZ FAD 7.07763
891 3ITJ FAD 7.10059
892 3ITJ CIT 7.10059
893 5BW4 SAM 7.11611
894 1UXG NAD 7.11974
895 1UXG FUM 7.11974
896 3NJ4 NAD 7.12644
897 6GNC FAD 7.14286
898 4Y24 TD2 7.14286
899 3FW3 ETS 7.14286
900 1EWJ BLM 7.14286
901 3Q87 SAM 7.2
902 5FEU NAP 7.2165
903 5X9D 80F 7.23684
904 4K55 H6P 7.25806
905 5Z21 NAI 7.26257
906 5OCM NAP 7.28477
907 3NUG NAD 7.28745
908 2HJR APR 7.31707
909 1LUA NAP 7.31707
910 3CBG SAH 7.32759
911 4MO2 FDA 7.33696
912 4MO2 FAD 7.33696
913 4JNA FAD 7.35294
914 3JQ3 ADP 7.37705
915 1GV0 NAD 7.41935
916 1GUZ NAD 7.41935
917 5AYV NAP 7.44337
918 5AYV KPL 7.44337
919 5EJ2 NAD 7.46753
920 3LXD FAD 7.46988
921 3VV1 GAL FUC 7.5
922 1D4D FAD 7.50552
923 4AP3 FAD 7.50552
924 4AP3 NAP 7.50552
925 3TLJ SAH 7.5067
926 6FHO FAD 7.5188
927 1K3T BRZ 7.52089
928 6ECU SAH 7.59494
929 1B8U NAD 7.59878
930 4ZSI GLP 7.60234
931 2C49 ADN 7.61589
932 6ECW SAH 7.61905
933 5MIT NAP 7.64526
934 5MIT FAD 7.64526
935 1E3W NAD 7.66284
936 5EES NAP 7.69231
937 5B09 4MX 7.69231
938 1OFZ FUC 7.69231
939 1E6W NAD 7.69231
940 2VVM FAD 7.72627
941 2VVL FAD 7.72627
942 4II2 ATP 7.72627
943 5UR6 8KM 7.73481
944 3QFA FAD 7.75862
945 2BHW NEX 7.75862
946 2B9W FAD 7.78302
947 4ITU NAI 7.80669
948 2GLX NDP 7.83133
949 4CJX NAP 7.83699
950 1LDN NAD 7.91139
951 6GNA FAD 7.98611
952 1VI2 NAD 8
953 4TSK NDP 8
954 3C3Y SAH 8.01688
955 4RPL FAD 8.02005
956 4RPL 3UC 8.02005
957 1MVQ MMA 8.05085
958 2RI1 GLP 8.08511
959 1E7S NAP 8.09969
960 5J60 FAD 8.125
961 4IPH 1FJ 8.13008
962 1PN0 IPH 8.16777
963 1PN0 FAD 8.16777
964 4IF4 BEF 8.17308
965 1GR0 NAD 8.17439
966 5C03 AGS 8.18713
967 1LDM NAD 8.20669
968 3OYW TDG 8.20895
969 3ABI NAD 8.21918
970 2F1K NAP 8.24373
971 2XYQ SAH 8.27586
972 1KZN CBN 8.29268
973 5FUI APY 8.33333
974 1NPD NAD 8.33333
975 4NBT NAD 8.33333
976 2DBZ NAP 8.38323
977 4MDH NAD 8.38323
978 1FL2 FAD 8.3871
979 2Q1W NAD 8.40841
980 5MDH NAD 8.40841
981 5NBW 8SK 8.41121
982 3WG3 A2G GAL NAG FUC 8.42697
983 4YCA NDP 8.5034
984 2FZW NAD 8.57909
985 2OOR NAD 8.59375
986 1F8G NAD 8.59375
987 1NM5 NAD 8.59375
988 2AQJ TRP 8.60927
989 2AQJ FAD 8.60927
990 2BGM NAJ 8.63309
991 5K7H IVC 8.65801
992 5TBM 79A 8.69565
993 3AGC RCC 8.69565
994 2PV7 NAD 8.72483
995 1C1L GAL BGC 8.75912
996 1A5Z NAD 8.77743
997 5U5G NAP 8.81356
998 5FPX GLY SER SER HIS HIS HIS HIS HIS 8.84956
999 4YSX FAD 8.86525
1000 6CZI 38E 8.92857
1001 1UPR 4IP 8.94309
1002 2B5W NAP 8.96359
1003 2VYN NAD 8.98204
1004 3PG7 PTY 8.98438
1005 2DIO EOD