Receptor
PDB id Resolution Class Description Source Keywords
4OH4 2.25 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF BRI1 IN COMPLEX WITH BKI1 ARABIDOPSIS THALIANA KINASE DOMAIN TRANSFERASE ATP BINDING PHOSPHORYLATION METRANSFERASE-SIGNALING PROTEIN COMPLEX
Ref.: STRUCTURAL INSIGHTS INTO THE NEGATIVE REGULATION OF SIGNALING BY BRI1-INTERACTING PROTEIN BKI1. CELL RES. V. 24 1328 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:1201;
B:1201;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4OH4 2.25 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF BRI1 IN COMPLEX WITH BKI1 ARABIDOPSIS THALIANA KINASE DOMAIN TRANSFERASE ATP BINDING PHOSPHORYLATION METRANSFERASE-SIGNALING PROTEIN COMPLEX
Ref.: STRUCTURAL INSIGHTS INTO THE NEGATIVE REGULATION OF SIGNALING BY BRI1-INTERACTING PROTEIN BKI1. CELL RES. V. 24 1328 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 4OH4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 4OH4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 4OH4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4OH4; Ligand: ANP; Similar sites found: 289
This union binding pocket(no: 1) in the query (biounit: 4oh4.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2IF8 ADP 0.0001113 0.43641 1.2012
2 3ORQ ADP 0.001124 0.42436 1.5015
3 3K5I ADP 0.001343 0.42054 1.5015
4 4WOP CTP 0.00906 0.40025 1.77778
5 3UDZ ADP 0.00002699 0.50954 1.8018
6 4AXD ANP 0.0001728 0.50212 1.8018
7 2VPQ ANP 0.0000937 0.49262 2.1021
8 3WO0 ALA 0.0008257 0.47011 2.1021
9 3DNT ATP 0.003209 0.42582 2.1021
10 3VPD ANP 0.000628 0.45378 2.13523
11 4C5N PXL 0.004445 0.43214 2.17391
12 4C5N ACP 0.004183 0.43214 2.17391
13 3TDV GDP 0.0001651 0.47262 2.28758
14 5A5W GUO 0.0197 0.40792 2.37154
15 4ZGP ADP 0.002357 0.42638 2.38908
16 2PUL ACP 0.00001212 0.51403 2.4024
17 1E4E ADP 0.001418 0.43406 2.4024
18 4CYI ATP 0.000008574 0.53402 2.51142
19 2BL9 CP6 0.01486 0.41083 2.52101
20 4OUJ LBT 0.002541 0.4573 2.60586
21 4OCJ NDG 0.0001462 0.50554 2.7027
22 5MW8 ATP 0.00006387 0.50005 2.7027
23 2VQD AP2 0.00009781 0.48737 2.7027
24 3I0O ADP 0.00005594 0.46284 2.7027
25 2R7K AMZ 0.007333 0.41562 2.7027
26 1GSA ADP 0.00004254 0.50793 3.003
27 4OCV ANP 0.00009631 0.4853 3.003
28 5TDF ADP 0.0008505 0.44592 3.003
29 4NV0 MG7 0.01604 0.40857 3.1348
30 2PHN GDP 0.005075 0.41688 3.14961
31 3VPC ADP 0.00008462 0.49242 3.19149
32 4R78 AMP 0.000009454 0.56305 3.23625
33 1I7L ATP 0.0002655 0.47441 3.23625
34 1IOW PHY 0.001179 0.45906 3.26797
35 5C1P DAL DAL 0.00267 0.43108 3.26797
36 5C1P ADP 0.0008536 0.4236 3.26797
37 4GYI ADP 0.000325 0.47548 3.3033
38 2HGS ADP 0.002256 0.43094 3.3033
39 5COU ATP 0.004011 0.40721 3.3033
40 3ZJX BOG 0.02376 0.40067 3.46021
41 1ZP9 ATP 0.00000186 0.53864 3.48837
42 1ZTH ADP 0.0000005763 0.5386 3.48837
43 2R85 AMP 0.008944 0.41429 3.6036
44 2YW2 ATP 0.002123 0.41197 3.6036
45 2CFM AMP 0.001609 0.41016 3.6036
46 2QK4 ATP 0.001365 0.40768 3.6036
47 3WVR AMP 0.0002494 0.45379 3.9039
48 1M0W ANP 0.0004401 0.44194 3.9039
49 3ETH ATP 0.001463 0.43748 3.9039
50 3TY5 ATP 0.00132 0.41207 3.9039
51 4LO2 GAL BGC 0.003917 0.44951 4.08163
52 4IX4 ADP 0.00001316 0.52581 4.2042
53 1EHI ADP 0.0006109 0.45011 4.2042
54 3VOT ADP 0.0001955 0.44576 4.2042
55 2AQX ATP 0.002179 0.42979 4.49827
56 4UWH JXM 0.002556 0.42909 4.5045
57 1W2D 4IP 0.002139 0.44013 4.5283
58 1W2D ADP 0.001895 0.4103 4.5283
59 5IQD GNP 0.00002511 0.54011 4.59016
60 5IQD RIO 0.000027 0.54011 4.59016
61 4RDL FUC GAL NDG FUC 0.002302 0.45482 4.87013
62 4CC6 L5Y 0.002189 0.44683 5.03145
63 3HAV ATP 0.0001133 0.42758 5.35117
64 3VPB ADP 0.00006323 0.44532 5.35714
65 1S9D AFB 0.009073 0.41199 5.91133
66 3KA2 2NC 0.02428 0.41106 5.91133
67 3V4S ATP 0.002724 0.42548 6.00601
68 3V4S ADP 0.008065 0.42119 6.00601
69 5LXT ACP 0.001671 0.40585 6.00601
70 5MY8 RXZ 0.0000004171 0.60272 6.30631
71 5IGI GMP 0.01384 0.41124 6.64452
72 5IGI ZIT 0.01457 0.41124 6.64452
73 4ZS4 ATP 0.000223 0.45988 6.84039
74 4OAV ACP 0.00000001716 0.63483 6.90691
75 4W6Z 8ID 0.007081 0.42607 7.20461
76 4O1P ANP 0.000000007115 0.66286 7.20721
77 5I35 ANP 0.0000005428 0.58854 7.50751
78 1PK8 ATP 0.000224 0.47963 7.50751
79 1AUX AGS 0.0002184 0.46733 7.50751
80 3PDT ADP 0.0005969 0.44105 7.63636
81 1T36 ADP 0.001488 0.4458 7.80781
82 3LQV ADE 0.001892 0.4674 7.82609
83 1IA9 ANP 0.00007581 0.47868 7.85714
84 3W0O ADP 0.0002903 0.48143 8.10811
85 3W0O HY0 0.0002903 0.40396 8.10811
86 4XYM A12 0.0003871 0.4588 8.26087
87 1YRO UDP 0.0255 0.40696 8.39161
88 5CKW ANP 0.000007744 0.49878 8.70871
89 4AZW ATP 0.000959 0.44362 9.00901
90 2BKK ADP 0.00007069 0.46868 9.46746
91 4U98 ACP 0.001292 0.43803 10.2102
92 4Q5H ANP 0.00002477 0.50853 10.8974
93 4WW7 AMP 0.000002896 0.55747 11.1111
94 5AWM ANP 0.00000002696 0.67679 12.9129
95 5K2M ADP 0.0002185 0.4782 13.2075
96 4DFU QUE 0.002041 0.45392 13.6646
97 2PYW ADP 0.000003449 0.55147 13.8138
98 4WB6 ATP 0.00000001804 0.66694 14.1141
99 3X01 AMP 0.001009 0.47033 14.2857
100 2GU8 796 0.00000001845 0.71384 14.4144
101 1RE8 BD2 0.00000002268 0.69746 14.4144
102 3IDB ANP 0.000000004252 0.68644 14.4144
103 2QCS ANP 0.00000001505 0.67051 14.4144
104 5C03 AGS 0.0000003955 0.58682 14.4144
105 4WB7 ATP 0.00000003766 0.48572 14.4144
106 4ANW O92 0.0009438 0.46082 14.4144
107 3FHI ANP 0.00000001402 0.67191 14.7147
108 4XBT 3ZQ 0.009618 0.40665 15.4839
109 4H3Q ANP 0.000000001748 0.70366 15.6156
110 4H3P ANP 0.000000001395 0.6937 15.6156
111 5GZ9 ANP 0.000000006143 0.67931 19.0164
112 3GNI ATP 0.0000000009799 0.66629 21.021
113 3VHE 42Q 0.0000003537 0.61522 22.5225
114 5VC5 96M 0.0000000001296 0.76714 23.1834
115 4WOV 3SM 0.0000001134 0.63701 23.4234
116 5W2I ADP 0.0003381 0.46969 23.8095
117 5W2I I3P 0.0003381 0.46969 23.8095
118 3F3E LEU 0.01699 0.40907 23.8095
119 2WU6 DKI 0.0000000007592 0.71983 24.6246
120 2ZV2 609 0.00000003331 0.67239 25.5034
121 4XH0 ADP 0.00001741 0.56158 25.8258
122 3TTI KBI 0.00000001105 0.55667 25.8258
123 3PTG 932 0.000000617 0.53208 25.8258
124 5X8I SQZ 0.00000002157 0.64187 26.1261
125 4UX9 ANP 0.00000001326 0.62187 26.1261
126 4IZY 1J2 0.0000007535 0.5503 26.1261
127 2WEL K88 0.000002067 0.4861 26.2997
128 5LXC 7AA 0.00000002053 0.62116 26.4264
129 2V7O DRN 0.00000000379 0.61157 26.4264
130 3E7O 35F 0.00003244 0.41856 26.4264
131 4OTH DRN 0.0000000587 0.58523 26.7267
132 4YLL 4E3 0.000001846 0.56873 26.7267
133 4IDT T28 0.00000004383 0.61796 27.3273
134 2VZ6 FEF 0.000001363 0.58656 27.476
135 4YZC STU 0.0000002619 0.63317 27.6276
136 1XJD STU 0.00000001203 0.6374 27.9279
137 5BYZ 4WE 0.000001116 0.47335 27.9279
138 4BHN BH9 0.00000002016 0.61378 28.2282
139 5T8O 76Z 0.0000000397 0.60135 28.2282
140 4WNK 453 0.000003275 0.57085 28.2282
141 5BVE 4VG 0.00000002212 0.71656 28.5285
142 4QTB 38Z 0.00000001694 0.67336 28.5285
143 3TXO 07U 0.00000008224 0.59632 28.5285
144 2VN9 GVD 0.0000002164 0.54807 28.5714
145 1TQP ATP 0.0000172 0.52772 28.5714
146 2V58 LZJ 0.003953 0.44427 28.5714
147 1OPK P16 0.0000147 0.43446 28.5714
148 2Q7D ANP 0.0006457 0.4043 28.5714
149 4KBA 1QM 0.000008227 0.46439 28.7009
150 4CLI 5P8 0.00000004759 0.67872 28.7462
151 3H9R TAK 0.000002398 0.50878 28.7879
152 5TA6 79D 0.000001271 0.49285 28.8288
153 4CRL C1I 0.0000001019 0.48402 28.8288
154 3ALN ANP 0.0000000008852 0.70991 29.052
155 2F2U M77 0.0000001543 0.64051 29.1291
156 5LI1 ANP 0.00000005235 0.63482 29.1291
157 5LI9 ACP 0.000009959 0.51594 29.1291
158 4BKJ STI 0.00015 0.48748 29.2063
159 1CM8 ANP 0.00000001803 0.63409 29.4294
160 4DC2 ADE 0.0000004613 0.49171 29.4294
161 4Y93 746 0.000006945 0.48044 29.4294
162 4Y85 499 0.000000887 0.5638 29.5181
163 5EKO N17 0.0007067 0.45345 29.7297
164 4FL3 ANP 0.00000003282 0.59619 30.03
165 3VRY B43 0.00000002995 0.55858 30.03
166 3GC0 AMP 0.0000002197 0.57088 30.0912
167 3LXK MI1 0.0000000369 0.65543 30.2752
168 1Y57 MPZ 0.000000006811 0.67731 30.3303
169 2H8H H8H 0.000000007559 0.66172 30.3303
170 4AU8 Z3R 0.0000002683 0.629 30.4054
171 1U5R ATP 0.000000001322 0.68198 30.6306
172 2PVF ACP 0.00000001394 0.63926 30.6306
173 3PP0 03Q 0.00000005945 0.53791 30.6306
174 3SXF BK5 0.00003831 0.52846 30.6306
175 3IGO ANP 0.00001216 0.49437 30.9309
176 4L9I 8PR 0.0001906 0.47508 30.9309
177 5HQ0 LZ9 0.0000000002601 0.68966 31.1258
178 2B9F ADP 0.000000005631 0.66729 31.2312
179 2B9H ADP 0.000000009725 0.66055 31.2312
180 2B9J ADP 0.00000001809 0.65438 31.2312
181 2B9I ADP 0.00000003294 0.63386 31.2312
182 3GC8 B45 0.0000001238 0.56967 31.2312
183 2CSN CKI 0.00000003784 0.65237 31.3131
184 5HX8 66P 0.000000001372 0.59794 31.457
185 4I6H 1C8 0.000008118 0.52964 31.4935
186 3O0G 3O0 0.000000009208 0.64657 31.5068
187 1UNH IXM 0.000000004241 0.63574 31.5068
188 3E8N ATP 0.000000000376 0.78124 31.5315
189 4E93 GUI 0.000000001719 0.72648 31.5315
190 1OUK 084 0.00004025 0.57905 31.5315
191 3E8N VRA 0.000000000376 0.48362 31.5315
192 4LOO SB4 0.0001522 0.47416 31.5315
193 5KO1 6UY 0.00000004274 0.63773 31.8021
194 5EFQ ADP 0.0000000003425 0.72028 31.8318
195 4NST ADP 0.000000000957 0.70083 31.8318
196 1O9U ADZ 0.0000001379 0.67177 31.8318
197 5JKG 6LF 0.00008941 0.51561 31.8328
198 3GQI ACP 0.00000006839 0.62003 31.9018
199 2QLU ADE 0.000001009 0.6184 32.1656
200 4FF8 14S 0.000009357 0.49361 32.1981
201 3EKK GS2 0.0000001416 0.466 32.2476
202 5HCY 60D 0.00000009246 0.66492 32.3263
203 3BU5 ATP 0.000000003937 0.67406 32.3529
204 3F7Z 34O 0.00000001609 0.64742 32.4324
205 3ZRM ZRM 0.00000007954 0.61718 32.4324
206 3RI1 3RH 0.0000003607 0.60801 32.5879
207 1VJY 460 0.0000000001448 0.77621 32.6733
208 4EWH T77 0.0000002197 0.51553 32.7273
209 3HZT J60 0.000005181 0.50815 32.7327
210 2BPM 529 0.000000004569 0.45094 33.0097
211 4NM5 ADP 0.00000008383 0.56611 33.033
212 2JLD AG1 0.00000001727 0.51162 33.033
213 3NW7 LGV 0.00002446 0.55153 33.2248
214 1V0O INR 0.00000001696 0.64995 33.3333
215 5VZ0 ADP 0.0004182 0.44968 33.3333
216 2X2M X2M 0.0000001056 0.62129 33.4395
217 5UR1 YY9 0.00002685 0.54577 33.4405
218 4AUA 4AU 0.00000115 0.56006 33.5505
219 2OO8 RAJ 0.0004041 0.46228 33.7539
220 5JFS 6K0 0.00000001666 0.69516 33.7662
221 4CFU 2WC 0.0000000002769 0.74683 33.9934
222 1K3A ACP 0.0000001743 0.57439 34.1137
223 3SLS ANP 0.0000000001094 0.68894 34.2105
224 4BCQ TJF 0.00000003686 0.58996 34.2193
225 4BCM T7Z 0.000000009486 0.58036 34.2193
226 2XMY CDK 0.00000006957 0.69541 34.2282
227 3HMO STU 0.00000009913 0.62144 34.2342
228 4BCN T9N 0.0000000002762 0.75911 34.3333
229 5TO8 7FM 0.000003232 0.58513 34.3972
230 4ASE AV9 0.000002663 0.57085 34.5345
231 5USZ SKE 0.000000004115 0.56775 34.6021
232 5JGA 6KC 0.0000001608 0.49186 34.6032
233 5CEO 50D 0.000001443 0.56233 34.6667
234 5LMK 6ZK 0.00000006143 0.60054 34.6801
235 4XLI 1N1 0.0000007571 0.58209 34.7015
236 3KRL KRL 0.000005183 0.54625 34.8348
237 3G5D 1N1 0.00000003257 0.70172 34.965
238 5UOX 8GY 0.000000009982 0.61167 35.0554
239 4TWP AXI 0.0000001444 0.42426 35.0554
240 4YMJ 4EJ 0.000000001774 0.76961 35.1974
241 4P5Z Q7M 0.0000001711 0.45721 35.4354
242 4AT3 LTI 0.0000004311 0.48592 35.4515
243 1PHK ATP 0.000000001838 0.69229 35.5705
244 3PLS ANP 0.000000004828 0.65909 35.5705
245 3KMW ATP 0.0000002296 0.58795 35.7934
246 2WEI VGG 0.0001067 0.46941 35.8885
247 1ZY5 ANP 0.0000001311 0.59802 35.9736
248 2A19 ANP 0.000000244 0.63097 36.2676
249 3KRR DQX 0.000000006156 0.7467 36.2712
250 4AG8 AXI 0.0000004716 0.45253 36.3924
251 5NKB 8ZT 0.00000003548 0.45635 36.6013
252 2HK5 1BM 0.0000003538 0.59511 37.037
253 3SRV S19 0.0000000001116 0.72687 37.1841
254 2Y6O 1N1 0.0000007973 0.58233 37.457
255 4F4P 0SB 0.00000004113 0.70069 37.7289
256 4QMN DB8 0.0000006332 0.45858 38.0645
257 2IO8 ADP 0.0002428 0.47615 38.0952
258 5FI4 5XV 0.009711 0.40419 38.0952
259 2F57 23D 0.000006893 0.51966 38.4858
260 4K33 ACP 0.00000005872 0.6263 38.7692
261 2OFV 242 0.00000003556 0.67191 38.9892
262 3C1X CKK 0.00009645 0.4899 39.9399
263 4BTK DTQ 0.0000005549 0.58041 40.2402
264 5N87 N66 0.0000001075 0.47764 40.2556
265 2XVD AS6 0.0000001457 0.63063 40.3974
266 1U59 STU 0.00000002052 0.64281 40.4181
267 5H2U 1N1 0.0000002673 0.59424 40.4494
268 5U6C 7YS 0.00000000863 0.61648 40.6349
269 5MJA 7O3 0.000001605 0.5421 40.6557
270 5DA3 58V 0.0000000207 0.68229 40.7547
271 4D2S DYK 0.000001405 0.53608 40.8451
272 1JPA ANP 0.00000007514 0.43339 41.0256
273 5HES 032 0.0000002529 0.60447 41.0423
274 4CSV STI 0.000009456 0.48585 41.0909
275 4FG8 ATP 0.000002482 0.55778 41.9048
276 5EOB 5QQ 0.000002632 0.60695 42.0063
277 4E1Z 0MX 0.00000009038 0.56667 42.6117
278 5FBN 5WF 0.0000006217 0.61192 42.8044
279 5C4L 4XR 0.00004674 0.51957 42.8571
280 5DBX ANP 0.00001154 0.5005 42.8571
281 5C4L SIS 0.0006971 0.46546 42.8571
282 4GJ3 0XP 0.0000000006099 0.74474 43.7086
283 3LXN MI1 0.000000003033 0.68631 45.283
284 1BYG STU 0.000000005355 0.6463 45.6835
285 4U0I 0LI 0.00001099 0.54856 45.7143
286 3SXS PP2 0.0000004184 0.55963 46.2687
287 5UKL SIX 0.00005541 0.51085 47.619
288 3PVW QRX 0.00002769 0.45553 47.619
289 5DZT AMP 0.0009952 0.40455 47.619
Pocket No.: 2; Query (leader) PDB : 4OH4; Ligand: ANP; Similar sites found: 16
This union binding pocket(no: 2) in the query (biounit: 4oh4.bio2) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1TDF NAP 0.04128 0.40861 1.58228
2 3KJS NAP 0.01304 0.40225 3.3033
3 1XKQ NDP 0.01645 0.40242 4.64286
4 3F8D FAD 0.04996 0.40439 4.64396
5 3RG9 NDP 0.01408 0.40773 5.41667
6 3RG9 WRA 0.01656 0.40749 5.41667
7 1RZ1 NAD 0.01221 0.41508 5.59006
8 1JUV NDP 0.007721 0.40978 5.69948
9 3G6N MET ALA SER 0.02476 0.40075 6.28272
10 2VPY MGD 0.04413 0.40386 7.11462
11 5V1B 8UY 0.02286 0.40253 10.4167
12 3T3C 017 0.01145 0.40349 12.1212
13 1XHL NDP 0.01156 0.40831 14.2857
14 4WHZ 3NL 0.0000007482 0.4107 25.8258
15 3OCP CMP 0.01697 0.40074 28.0576
16 4OYA 1VE 0.01745 0.42271 38.0952
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