Receptor
PDB id Resolution Class Description Source Keywords
4OBW 2.4 Å EC: 2.1.1.201 CRYSTAL STRUCTURE OF YEAST COQ5 IN THE SAM BOUND FORM SACCHAROMYCES CEREVISIAE ROSSMANN FOLD METHYLTRANSFERASE TRANSFERASE
Ref.: CRYSTAL STRUCTURES AND CATALYTIC MECHANISM OF THE C-METHYLTRANSFERASE COQ5 PROVIDE INSIGHTS INTO A KE THE YEAST COENZYME Q SYNTHESIS PATHWAY. ACTA CRYSTALLOGR.,SECT.D V. 70 2085 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM D:601;
A:602;
C:601;
B:601;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
TAM A:601;
D:602;
Invalid;
Invalid;
none;
none;
submit data
163.215 C7 H17 N O3 C(CO)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4OBW 2.4 Å EC: 2.1.1.201 CRYSTAL STRUCTURE OF YEAST COQ5 IN THE SAM BOUND FORM SACCHAROMYCES CEREVISIAE ROSSMANN FOLD METHYLTRANSFERASE TRANSFERASE
Ref.: CRYSTAL STRUCTURES AND CATALYTIC MECHANISM OF THE C-METHYLTRANSFERASE COQ5 PROVIDE INSIGHTS INTO A KE THE YEAST COENZYME Q SYNTHESIS PATHWAY. ACTA CRYSTALLOGR.,SECT.D V. 70 2085 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4OBW - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4OBW - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4OBW - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4OBW; Ligand: SAM; Similar sites found: 578
This union binding pocket(no: 1) in the query (biounit: 4obw.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1U7T TDT 0.005825 0.4317 None
2 1H5Q NAP 0.005904 0.4204 1.16732
3 4ZCC NAI 0.009075 0.43029 1.55642
4 4ZCC FAD 0.009075 0.43029 1.55642
5 3U4C NDP 0.004616 0.42261 1.55642
6 4EIP FAD 0.0152 0.41469 1.55642
7 1X7D ORN 0.01416 0.40968 1.55642
8 1X7D NAD 0.008975 0.40958 1.55642
9 1KYQ NAD 0.004777 0.40331 1.55642
10 1QAN SAH 0.00004371 0.50187 1.63934
11 3DUW SAH 0.001325 0.43328 1.79372
12 3OU2 SAH 0.00004339 0.44973 1.83486
13 2CDU FAD 0.0009121 0.46379 1.94553
14 3BGD PM6 0.0005985 0.46098 1.94553
15 3BGD SAH 0.0004533 0.45941 1.94553
16 4HA6 FAD 0.005679 0.43411 1.94553
17 3CH6 311 0.01767 0.42245 1.94553
18 3CH6 NAP 0.01767 0.42245 1.94553
19 2X3N FAD 0.01283 0.41168 1.94553
20 4K5S FAD 0.01299 0.40714 1.94553
21 4K5S PM0 0.02545 0.40714 1.94553
22 3AFN NAP 0.01313 0.40692 1.94553
23 4Q9N NAI 0.01648 0.40008 1.94553
24 1XTP SAI 0.00001262 0.51798 1.9685
25 1PR9 NAP 0.008367 0.41592 2.04918
26 3D3W NAP 0.01082 0.41079 2.04918
27 4AZW SAM 0.000001698 0.55819 2.33463
28 3T7S SAM 0.00001239 0.51832 2.33463
29 2EFJ SAH 0.00002085 0.50059 2.33463
30 4DMG SAM 0.0001068 0.50052 2.33463
31 1BC5 SAH 0.0000874 0.49081 2.33463
32 3C6K SPD 0.000393 0.48068 2.33463
33 3C6K MTA 0.000393 0.48068 2.33463
34 1ZQ9 SAM 0.0003416 0.4565 2.33463
35 3GD4 FAD 0.005064 0.44705 2.33463
36 3GD4 NAD 0.007654 0.44705 2.33463
37 5XLX SAH 0.0007423 0.44203 2.33463
38 2GDZ NAD 0.00206 0.4398 2.33463
39 5JCM ISD 0.008793 0.43931 2.33463
40 5JCM NAD 0.008793 0.43931 2.33463
41 5JCM FAD 0.008538 0.43931 2.33463
42 5FJN FAD 0.005015 0.43572 2.33463
43 5FJN BE2 0.005732 0.43572 2.33463
44 4CNK FAD 0.005596 0.42951 2.33463
45 4FC7 COA 0.007122 0.42853 2.33463
46 4FC7 NAP 0.007122 0.42853 2.33463
47 2G5C NAD 0.00439 0.42495 2.33463
48 5JAQ NAI 0.0087 0.42157 2.33463
49 3UOY NAP 0.02595 0.41713 2.33463
50 3UOY FAD 0.02595 0.41713 2.33463
51 5EB4 FAD 0.01188 0.41618 2.33463
52 3QWI CUE 0.01254 0.41602 2.33463
53 3QWI NAP 0.007843 0.41602 2.33463
54 4J36 FAD 0.008444 0.41574 2.33463
55 3A4V NAD 0.009981 0.41572 2.33463
56 3A4V PYR 0.009981 0.41572 2.33463
57 4J36 1HR 0.01528 0.41374 2.33463
58 2BRY FAD 0.01102 0.41042 2.33463
59 2Y6Q I7T 0.02038 0.41024 2.33463
60 2Y6Q FAD 0.01049 0.41024 2.33463
61 4TXI FAD 0.01204 0.40751 2.33463
62 3O7W SAM 0.00003791 0.47771 2.38095
63 2XVM SAH 0.000002682 0.52193 2.51256
64 5LOG SAH 0.0006113 0.4478 2.57511
65 3CBG SAH 0.002999 0.41224 2.58621
66 1Z3C SA8 0.000004134 0.56163 2.72374
67 1G60 SAM 0.00001967 0.51226 2.72374
68 3X0D SAH 0.0001138 0.47933 2.72374
69 3A25 SAM 0.0003031 0.45873 2.72374
70 5ULP KB1 0.0006349 0.45479 2.72374
71 4ITU 1HS 0.002608 0.4491 2.72374
72 4ITU NAI 0.001577 0.4491 2.72374
73 5G3U FDA 0.002271 0.44774 2.72374
74 5G3U ITW 0.003507 0.44495 2.72374
75 2Q7V FAD 0.0042 0.43838 2.72374
76 5I39 FAD 0.00439 0.43442 2.72374
77 4JNA FAD 0.006052 0.43187 2.72374
78 4TM3 FAD 0.01667 0.4273 2.72374
79 2C7G FAD 0.01599 0.42127 2.72374
80 1PS9 FAD 0.01024 0.42016 2.72374
81 1H82 FAD 0.01723 0.41969 2.72374
82 1H82 GZZ 0.02009 0.41969 2.72374
83 2V6G NAP 0.007567 0.4155 2.72374
84 4EMI NAD 0.02414 0.41512 2.72374
85 4EMI FAD 0.01138 0.41512 2.72374
86 5EZ7 FAD 0.01777 0.40701 2.72374
87 5D4V SAH 0.00684 0.40595 2.72374
88 1E5Q NDP 0.01105 0.40549 2.72374
89 2RH4 EMO 0.02812 0.40273 2.72374
90 2GMM MAN MAN 0.02467 0.40349 2.77778
91 2BD0 NAP 0.009376 0.41248 2.86885
92 4NBT NAD 0.01371 0.40126 2.91667
93 3H2B SAH 0.0001352 0.4761 2.95567
94 4M73 M72 0.00000102 0.60173 3.11284
95 4M73 SAH 0.000001827 0.58839 3.11284
96 4KIB SAH 0.00001592 0.50619 3.11284
97 1KPH SAH 0.0001102 0.48433 3.11284
98 2FK8 SAM 0.00006099 0.47301 3.11284
99 1KPG SAH 0.0001127 0.45554 3.11284
100 3P9C SAH 0.00115 0.45404 3.11284
101 5BR7 FAD 0.004558 0.45139 3.11284
102 5BR7 FLC 0.005089 0.44905 3.11284
103 3AYI HCI 0.004762 0.44537 3.11284
104 3AYI FAD 0.004587 0.44537 3.11284
105 3EVG SAH 0.0007384 0.44213 3.11284
106 4RSL FAD 0.003365 0.43759 3.11284
107 3CTY FAD 0.005138 0.43708 3.11284
108 1XHC FAD 0.003693 0.43572 3.11284
109 3VYW SAM 0.0006853 0.43142 3.11284
110 1ZBQ NAD 0.003893 0.42991 3.11284
111 4FWE FAD 0.007832 0.4275 3.11284
112 1E1M FAD 0.01234 0.42533 3.11284
113 1E1M NAP 0.01234 0.42533 3.11284
114 2FR1 NDP 0.006258 0.4205 3.11284
115 1G0N PHH 0.01576 0.41133 3.11284
116 1GPE FAD 0.01862 0.41132 3.11284
117 2NVK FAD 0.01579 0.41128 3.11284
118 1FL2 FAD 0.01458 0.41105 3.11284
119 1G0N NDP 0.0145 0.4102 3.11284
120 3GMB FAD 0.01519 0.40512 3.11284
121 4AT0 FAD 0.02709 0.40507 3.11284
122 3OID NDP 0.01469 0.40469 3.11284
123 3WLE NAD 0.01946 0.40223 3.11284
124 3DXY SAM 0.00008343 0.45824 3.21101
125 2EWM NAD 0.007024 0.41697 3.21285
126 3GEG NAD 0.001037 0.45029 3.23887
127 3I53 SAH 0.0002008 0.47086 3.31325
128 2HNK SAH 0.00302 0.4197 3.34728
129 4AZT SAM 0.0000004285 0.58102 3.50195
130 3G2O SAM 0.000001144 0.56271 3.50195
131 3GDH SAH 0.000002752 0.49733 3.50195
132 2ZIF SAM 0.00005652 0.49246 3.50195
133 5DX1 SFG 0.0001288 0.48727 3.50195
134 3NDJ SAH 0.0007694 0.47812 3.50195
135 3NDJ JHZ 0.0007694 0.47812 3.50195
136 4N49 SAM 0.0002214 0.46902 3.50195
137 1RJD SAM 0.0002942 0.46365 3.50195
138 3A27 SAM 0.0003182 0.45782 3.50195
139 5K8V 6RE 0.003271 0.45403 3.50195
140 1KYZ SAH 0.0004143 0.4529 3.50195
141 5DWQ SFG 0.0008435 0.44934 3.50195
142 2Z3Y F2N 0.002877 0.44806 3.50195
143 5DX8 SFG 0.0009033 0.44626 3.50195
144 5DXA SFG 0.0009108 0.4461 3.50195
145 5DX0 SFG 0.001117 0.44564 3.50195
146 4MIG G3F 0.005629 0.43866 3.50195
147 5JJR SAH 0.001167 0.43359 3.50195
148 2GV8 FAD 0.004132 0.43116 3.50195
149 1VQW FAD 0.004909 0.42653 3.50195
150 2GVC FAD 0.005086 0.42583 3.50195
151 1NAA 6FA 0.009561 0.4234 3.50195
152 1NAA ABL 0.01353 0.4234 3.50195
153 1KYZ FER 0.005121 0.41919 3.50195
154 1FP2 SAH 0.009241 0.41619 3.50195
155 5TTJ FAD 0.01196 0.4151 3.50195
156 3V1U NAD 0.01039 0.40259 3.50195
157 1R18 SAH 0.000003558 0.54946 3.52423
158 2JAH NDP 0.01575 0.40099 3.64372
159 5FA8 SAM 0.00000653 0.54029 3.72671
160 5KOK S9T 0.00008357 0.50888 3.89105
161 2EG5 SAH 0.000009378 0.50101 3.89105
162 3VC1 SAH 0.0002613 0.49383 3.89105
163 3VC1 GST 0.0002613 0.49383 3.89105
164 5KOK SAH 0.00005675 0.49238 3.89105
165 5KOK R9T 0.0003141 0.48113 3.89105
166 4RPL 3UC 0.002749 0.46556 3.89105
167 4RPL FAD 0.003092 0.46104 3.89105
168 4DCM SAM 0.0001392 0.46039 3.89105
169 1F3L SAH 0.0004304 0.45848 3.89105
170 1YQZ FAD 0.004748 0.44913 3.89105
171 4LWP SAH 0.0006491 0.44453 3.89105
172 3SQP FAD 0.03154 0.43995 3.89105
173 4OPC PGT 0.01859 0.43904 3.89105
174 4OPC FDA 0.01638 0.43904 3.89105
175 3EYA FAD 0.003099 0.43809 3.89105
176 1RSG FAD 0.004718 0.43697 3.89105
177 1YY5 FAD 0.006344 0.43274 3.89105
178 5KMS NAD 0.01207 0.42862 3.89105
179 5J60 FAD 0.00673 0.42778 3.89105
180 4HXY NDP 0.004146 0.42738 3.89105
181 1UP7 NAD 0.003246 0.42507 3.89105
182 2E5V FAD 0.009662 0.42318 3.89105
183 1Y8Q ATP 0.0006656 0.41425 3.89105
184 1LTH NAD 0.00821 0.40998 3.89105
185 4NTD FAD 0.01579 0.40846 3.89105
186 1OBB NAD 0.007605 0.40712 3.89105
187 1SOW NAD 0.01331 0.40551 3.89105
188 5KMS FAD 0.01822 0.40357 3.89105
189 1LVL NAD 0.003793 0.40072 3.89105
190 3TN7 NJP 0.01632 0.40028 3.89105
191 3HVJ 705 0.0004814 0.47786 4.0724
192 3JWH SAH 0.000003654 0.5068 4.14747
193 3GRU AMP 0.0001077 0.48683 4.28016
194 1ELI PYC 0.0009606 0.46512 4.28016
195 2AE2 NAP 0.004287 0.43696 4.28016
196 2AE2 PTO 0.004287 0.43696 4.28016
197 4MOP 2H5 0.007794 0.43425 4.28016
198 1I8T FAD 0.005073 0.43253 4.28016
199 4XQC NAD 0.007838 0.42748 4.28016
200 1G8K MGD 0.01675 0.4272 4.28016
201 1E3W NAD 0.004669 0.42373 4.28016
202 4YRY NAD 0.0189 0.41633 4.28016
203 4M52 FAD 0.01444 0.41402 4.28016
204 4YRY FAD 0.01567 0.41234 4.28016
205 4UCI SAM 0.004081 0.41216 4.28016
206 3IHG FAD 0.0081 0.41159 4.28016
207 4REP FAD 0.01476 0.41081 4.28016
208 4XQC 13D 0.0197 0.40933 4.28016
209 4O1M NAD 0.009762 0.40922 4.28016
210 5MZI FAD 0.03485 0.40659 4.28016
211 5MZI FYK 0.03586 0.40659 4.28016
212 1V6A TRE 0.02259 0.404 4.28016
213 2YG3 FAD 0.02234 0.40325 4.28016
214 3RJ5 NAD 0.02203 0.40168 4.33071
215 3EGI ADP 0.0001115 0.42913 4.36893
216 5T2U NAP 0.008115 0.41653 4.43548
217 2AG5 NAD 0.002022 0.44017 4.47154
218 2JJQ SAH 0.00003726 0.51547 4.66926
219 5MW4 5JU 0.0001426 0.50613 4.66926
220 3QOX SAH 0.00009618 0.48898 4.66926
221 3LST SAH 0.000166 0.48569 4.66926
222 4BLW AMP 0.0008148 0.46353 4.66926
223 4KGD TDP 0.00423 0.45693 4.66926
224 1FP1 SAH 0.000191 0.45593 4.66926
225 4KGD FAD 0.00481 0.45477 4.66926
226 4BLW SAH 0.0008151 0.45337 4.66926
227 2JHP SAH 0.0003458 0.45142 4.66926
228 1QO8 FAD 0.003721 0.44183 4.66926
229 1V5F FAD 0.008448 0.43953 4.66926
230 5O4J SAH 0.004818 0.4281 4.66926
231 5O4J 9KH 0.004818 0.4281 4.66926
232 1REO FAD 0.006777 0.42665 4.66926
233 3LZW FAD 0.00651 0.42644 4.66926
234 5O4J PJL 0.005561 0.42405 4.66926
235 2WPF FAD 0.03823 0.41912 4.66926
236 2V3V MGD 0.02701 0.41845 4.66926
237 2WPF WPF 0.04509 0.41657 4.66926
238 3S5W FAD 0.007447 0.41582 4.66926
239 3O03 NAP 0.007838 0.40949 4.66926
240 4EMJ FAD 0.009774 0.4192 4.6729
241 2HMT NAI 0.000006271 0.53871 4.86111
242 3AD8 NAD 0.005376 0.42591 5.05051
243 5GWX SAM 0.00002757 0.51893 5.05837
244 5GWX SAR 0.00002757 0.51893 5.05837
245 4RVG SAM 0.0004211 0.48527 5.05837
246 4RVG TYD 0.0005256 0.48292 5.05837
247 3EVF SAH 0.001249 0.45748 5.05837
248 3EVF GTA 0.001482 0.45748 5.05837
249 4MO2 FDA 0.002355 0.44589 5.05837
250 5BUK FAD 0.003989 0.44229 5.05837
251 1IY8 NAD 0.002692 0.4359 5.05837
252 5HSA FAS 0.007591 0.42629 5.05837
253 3GGO ENO 0.01289 0.41635 5.05837
254 3GGO NAI 0.01289 0.41635 5.05837
255 1OAA OAA 0.01568 0.4132 5.05837
256 1DMR PGD 0.03502 0.4106 5.05837
257 3LCC SAH 0.00001924 0.50307 5.10638
258 1XCL SAH 0.000889 0.45913 5.10638
259 3RFV 15L 0.006282 0.41379 5.24345
260 3RFV NAI 0.01065 0.40489 5.24345
261 5XVK SAH 0.00002239 0.51679 5.44747
262 1UWK URO 0.0003685 0.49231 5.44747
263 1UWK NAD 0.0003685 0.49231 5.44747
264 1NW5 SAM 0.00008933 0.48387 5.44747
265 3GCZ SAM 0.0002583 0.46171 5.44747
266 3OND NAD 0.006335 0.43537 5.44747
267 3OND ADN 0.006335 0.43537 5.44747
268 2HQM FAD 0.007026 0.42881 5.44747
269 2RAB NAD 0.01686 0.42589 5.44747
270 2R4J FAD 0.01541 0.41992 5.44747
271 2R4J 13P 0.01541 0.41992 5.44747
272 4C3Y FAD 0.01399 0.41376 5.44747
273 4C3Y ANB 0.02051 0.41011 5.44747
274 4YDD MGD 0.04029 0.40966 5.44747
275 4YDD MD1 0.04029 0.40966 5.44747
276 4D7E FAD 0.01377 0.40923 5.44747
277 2Q0L FAD 0.02056 0.40586 5.44747
278 1EU1 MGD 0.01851 0.40425 5.44747
279 1BXK NAD 0.01389 0.40101 5.44747
280 2DKN NAI 0.01156 0.40462 5.4902
281 2WSB NAD 0.002297 0.44966 5.51181
282 3NUG NAD 0.002039 0.44138 5.66802
283 2O07 MTA 0.00007441 0.50152 5.83658
284 2O07 SPD 0.00008864 0.50152 5.83658
285 1X87 NAD 0.0002351 0.47193 5.83658
286 5XVQ SAH 0.00003553 0.465 5.83658
287 5CUQ NSC 0.0008584 0.45982 5.83658
288 2DPM SAM 0.001043 0.44168 5.83658
289 5M67 NAD 0.006785 0.43478 5.83658
290 5M67 ADE 0.007071 0.43392 5.83658
291 5IL1 SAM 0.001268 0.43205 5.83658
292 5M67 3D1 0.007941 0.4315 5.83658
293 1PN0 IPH 0.01085 0.425 5.83658
294 1PN0 FAD 0.01044 0.425 5.83658
295 5K7U SAM 0.001882 0.42468 5.83658
296 3ZV6 4HB 0.01158 0.41855 5.83658
297 3ZV6 NAD 0.01108 0.41855 5.83658
298 4J4H 1J1 0.01449 0.41736 5.83658
299 4J4H NAI 0.01449 0.41736 5.83658
300 4G74 UQ5 0.01861 0.41293 5.83658
301 4G74 FAD 0.01236 0.4114 5.83658
302 4JK3 NAD 0.00732 0.41082 5.83658
303 1JA9 NDP 0.01054 0.41014 5.83658
304 2CFC NAD 0.008933 0.40967 5.83658
305 5ITV NAI 0.0006549 0.46376 5.88235
306 3C3Y SAH 0.001199 0.43517 5.90717
307 1P1C SAH 0.0002175 0.47342 6.03015
308 4KRG SAH 0.000007507 0.52135 6.22568
309 1DL5 SAH 0.00006115 0.50351 6.22568
310 4M38 SAH 0.00003968 0.50145 6.22568
311 3LCV SAM 0.00008578 0.49117 6.22568
312 4M37 SAH 0.00009168 0.48339 6.22568
313 3ELW SAM 0.001309 0.46216 6.22568
314 3ELW GP3 0.001378 0.46216 6.22568
315 1U2Z SAH 0.0004133 0.46118 6.22568
316 2WA2 SAM 0.0002282 0.4579 6.22568
317 2C31 TZD 0.006686 0.44884 6.22568
318 2C31 ADP 0.006507 0.44884 6.22568
319 1O97 FAD 0.004996 0.44588 6.22568
320 1O97 AMP 0.004996 0.44588 6.22568
321 2C5A GDC 0.007135 0.43687 6.22568
322 2C5A NAD 0.007135 0.43687 6.22568
323 4BV6 FAD 0.008245 0.4246 6.22568
324 3GDN HBX 0.017 0.41712 6.22568
325 3GDN FAD 0.01242 0.41712 6.22568
326 2B4Q NAP 0.01031 0.40814 6.22568
327 2YVF NAD 0.04548 0.40204 6.22568
328 2YVF FAD 0.04426 0.40204 6.22568
329 4Z24 FAD 0.02597 0.40191 6.22568
330 4D79 ATP 0.00675 0.40083 6.22568
331 1XSE NDP 0.02596 0.40016 6.22568
332 2F5Z FAD 0.004618 0.43836 6.25
333 2Q2V NAD 0.01793 0.4007 6.27451
334 4XUC 43G 0.0003796 0.47874 6.42202
335 4XUC SAM 0.0003796 0.47874 6.42202
336 1IM8 SAI 0.0000006525 0.57894 6.55738
337 4C4A SAH 0.00001053 0.52398 6.61479
338 4NEC SAH 0.00001913 0.52226 6.61479
339 1I9G SAM 0.00007305 0.48994 6.61479
340 3DMH SAM 0.00003913 0.47869 6.61479
341 1ZGA SAH 0.0001972 0.45103 6.61479
342 3VSE SAH 0.00011 0.4496 6.61479
343 3HDY FDA 0.006854 0.4427 6.61479
344 3HDY GDU 0.00707 0.4427 6.61479
345 3HDY FAD 0.007362 0.44117 6.61479
346 1RYI FAD 0.005935 0.43132 6.61479
347 3DMH GMP 0.00006372 0.42938 6.61479
348 3E1T FAD 0.008885 0.4249 6.61479
349 2VVL FAD 0.0171 0.40964 6.61479
350 1NFQ NAI 0.01188 0.40776 6.61479
351 2VVM FAD 0.01964 0.40589 6.61479
352 3P2E SAH 0.00008195 0.48777 6.66667
353 1EJ0 SAM 0.0002527 0.46212 6.66667
354 2VDV SAM 0.00002129 0.52663 6.91057
355 5BW4 SAM 0.00004185 0.48952 7.00389
356 1OMO NAD 0.003488 0.4221 7.00389
357 1XKQ NDP 0.01059 0.41122 7.00389
358 5DM1 5D7 0.00003636 0.53257 7.11611
359 5DM1 SAH 0.00003401 0.53257 7.11611
360 4GKV NAD 0.00488 0.42784 7.14286
361 4HSU FAD 0.01003 0.42328 7.25806
362 4GUT FAD 0.01173 0.42174 7.25806
363 4GUS FAD 0.01134 0.42075 7.25806
364 4O0L NDP 0.008159 0.41401 7.27273
365 1N2X SAM 0.0002078 0.47429 7.393
366 3ML1 MGD 0.0141 0.43208 7.393
367 3NYC FAD 0.009221 0.42996 7.393
368 3NYC IAR 0.009221 0.42996 7.393
369 3LKZ SFG 0.001647 0.42921 7.393
370 3VPH OXM 0.006818 0.42229 7.393
371 5KVA SAM 0.003236 0.42018 7.393
372 1Z6Z NAP 0.01068 0.40744 7.393
373 4J7U NAP 0.0245 0.40311 7.393
374 4J7U YTZ 0.0245 0.40311 7.393
375 3Q9T FAY 0.02297 0.40082 7.393
376 4FN4 NAD 0.001411 0.44723 7.48031
377 3FZG SAM 0.0005031 0.45857 7.5
378 3FPF TNA 0.0001465 0.50435 7.7821
379 3FPF MTA 0.0001465 0.50435 7.7821
380 4POO SAM 0.0004583 0.46104 7.7821
381 5BVA FAD 0.00204 0.45609 7.7821
382 3CGD NAD 0.006732 0.45151 7.7821
383 3CGD FAD 0.006732 0.45151 7.7821
384 3CGD COA 0.006732 0.45151 7.7821
385 3ZNN FAD 0.004365 0.44947 7.7821
386 3ZNN 4WL 0.004365 0.44947 7.7821
387 4X9M FAD 0.004185 0.43746 7.7821
388 3CGB FAD 0.004051 0.43497 7.7821
389 1AE1 NAP 0.004177 0.42974 7.7821
390 5U8U FAD 0.01694 0.42519 7.7821
391 1JQD SAH 0.00007502 0.41907 7.7821
392 2IV2 MGD 0.008932 0.41796 7.7821
393 2UYQ SAM 0.00008524 0.40965 7.7821
394 1JQD HSM 0.0003506 0.40961 7.7821
395 4YMH SAH 0.00007282 0.48999 7.91667
396 2GAG FAD 0.0048 0.43939 8.08081
397 2GAG FOA 0.006586 0.43285 8.08081
398 2GAG NAD 0.005685 0.42813 8.08081
399 5E9W SAH 0.000001465 0.52158 8.17121
400 3TKY SAH 0.0001487 0.47432 8.17121
401 4YNU LGC 0.009724 0.42727 8.17121
402 4YNU FAD 0.01002 0.42331 8.17121
403 2IVF MGD 0.02346 0.40039 8.17121
404 1KOL NAD 0.005672 0.4271 8.29146
405 1SQF SAM 0.000005902 0.53214 8.56031
406 5X62 SAH 0.00001786 0.5043 8.56031
407 2OBF SAH 0.0001786 0.5039 8.56031
408 2OBF F83 0.0001786 0.5039 8.56031
409 4DSG FAD 0.009071 0.43605 8.56031
410 4DSG UDP 0.009071 0.43605 8.56031
411 1KNR FAD 0.007674 0.4251 8.56031
412 3NTD FAD 0.008707 0.42055 8.56031
413 1FEC FAD 0.02174 0.4089 8.56031
414 1L3I SAH 0.00001722 0.52804 8.85417
415 5F2K SAH 0.000144 0.49512 8.94942
416 5F2K OCA 0.000144 0.49512 8.94942
417 4TQG NDP 0.00529 0.41994 8.94942
418 3AB1 FAD 0.0131 0.41418 8.94942
419 2ZJ1 NAD 0.02514 0.40887 8.94942
420 2ZJ1 ARJ 0.02784 0.40672 8.94942
421 1WY7 SAH 0.0001966 0.47335 9.17874
422 2AOT SAH 0.00001097 0.5067 9.33852
423 4GQB 0XU 0.0000845 0.49346 9.33852
424 3S1S SAH 0.00009135 0.48997 9.33852
425 5FA5 MTA 0.0001859 0.45491 9.33852
426 2RGO FAD 0.002039 0.4488 9.33852
427 4MP8 NAD 0.006611 0.42509 9.33852
428 1GTE FAD 0.0258 0.41369 9.33852
429 2WOX NDP 0.01223 0.40946 9.33852
430 3OZ2 FAD 0.01794 0.40775 9.33852
431 3MB5 SAM 0.00001374 0.52609 9.41177
432 4CQM NAP 0.002471 0.43623 9.42623
433 3Q87 SAM 0.00008143 0.49216 9.6
434 2V3B FAD 0.01037 0.41598 9.63542
435 2V3A FAD 0.0126 0.41305 9.63542
436 2PX8 SAH 0.003516 0.41302 9.66543
437 1V59 FAD 0.004066 0.44281 9.72763
438 3SSO SAH 0.001941 0.42805 9.72763
439 1V59 NAD 0.0009372 0.41879 9.72763
440 1GET FAD 0.02549 0.41695 9.72763
441 1GET NAP 0.02685 0.41695 9.72763
442 5MBX FAD 0.02761 0.40899 9.72763
443 5MBX SP5 0.02761 0.40899 9.72763
444 2PXX SAH 0.000005908 0.53481 9.76744
445 3FUU ADN 0.0001357 0.47604 10.1167
446 2Q28 ADP 0.0004974 0.45167 10.1167
447 3KLJ FAD 0.001808 0.44639 10.1167
448 5DNK SAH 0.0001765 0.43705 10.1167
449 4NBW NAD 0.00837 0.40961 10.1167
450 3OFK SAH 0.000001888 0.52233 10.1852
451 3UCL CYH 0.01377 0.42967 10.5058
452 3UCL NAP 0.01495 0.42967 10.5058
453 3UCL FAD 0.01377 0.42967 10.5058
454 2DTX BMA 0.007795 0.4238 10.6061
455 3FRH SAH 0.000213 0.47382 10.6719
456 1Q0S SAH 0.000132 0.4849 10.8108
457 3G89 SAM 0.00001875 0.48921 10.8434
458 4II2 ATP 0.002991 0.41988 10.8434
459 4PIO SAH 0.0001668 0.49512 10.8949
460 4PIO AVI 0.0002211 0.48809 10.8949
461 4EUE NAI 0.002416 0.43935 10.8949
462 4ONQ SFG 0.001881 0.42469 10.8949
463 5L13 6ZE 0.02301 0.41074 10.8949
464 5ODQ FAD 0.02441 0.40319 10.8949
465 1E6E FAD 0.007943 0.42032 10.9375
466 1NV8 MEQ 0.0001068 0.4945 11.284
467 1NV8 SAM 0.0001166 0.4945 11.284
468 1YBH FAD 0.001806 0.45348 11.284
469 3WGT FAD 0.004317 0.44333 11.284
470 3WGT QSC 0.004497 0.44333 11.284
471 5WGR FAD 0.004045 0.43815 11.284
472 1RP0 AHZ 0.003529 0.43185 11.284
473 1MUU NAD 0.01104 0.40283 11.284
474 1MV8 NAD 0.01121 0.40253 11.284
475 3ICS FAD 0.004196 0.43533 11.6732
476 4AP3 NAP 0.009617 0.4348 11.6732
477 4AP3 FAD 0.009617 0.4348 11.6732
478 3ICR FAD 0.004316 0.43369 11.6732
479 3ICT FAD 0.005558 0.42859 11.6732
480 2E7Z MGD 0.01797 0.40281 11.6732
481 4A6D SAM 0.0003222 0.45981 12.0623
482 4USR FAD 0.01355 0.4063 12.0623
483 2CUL FAD 0.007736 0.41976 12.069
484 1L1E SAH 0.00009049 0.4859 12.4514
485 5F8F SFG 0.00004382 0.48203 12.4514
486 3PT9 SAH 0.00009969 0.47946 12.4514
487 4YAG NAI 0.003731 0.44177 12.4514
488 2BZG SAH 0.001341 0.431 12.5
489 1XDS SAM 0.00004624 0.51117 12.8342
490 1TPY SAH 0.0001079 0.48472 12.8405
491 2YY7 NAD 0.001449 0.4481 12.8405
492 1BZL FAD 0.0412 0.41783 12.8405
493 3MQ2 SAH 0.0003614 0.44996 12.844
494 2ZFU SAH 0.00005447 0.49547 13.0233
495 2ZWA SAH 0.0004171 0.45908 13.2296
496 3GWZ SAH 0.0001167 0.4578 13.2296
497 3GXO SAH 0.000322 0.4468 13.2296
498 2P41 SAH 0.0009089 0.43826 13.2296
499 1XHL NDP 0.004587 0.42666 13.2296
500 1V8B NAD 0.007117 0.42253 13.2296
501 1I1N SAH 0.000007868 0.54521 13.2743
502 3H8V ATP 0.001955 0.42398 13.3562
503 3BXO SAM 0.0000003743 0.55611 13.3891
504 1JG3 ADN 0.00009238 0.48088 13.617
505 2A14 SAH 0.0000212 0.5156 13.6187
506 5E72 SAM 0.00008074 0.49023 13.6187
507 4Y2H 49K 0.001081 0.46386 13.6187
508 4Y2H SAH 0.001105 0.46344 13.6187
509 2DKH FAD 0.003781 0.43172 13.6187
510 2DKH 3HB 0.005278 0.43172 13.6187
511 2XVE FAD 0.01743 0.4221 13.6187
512 2XVF FAD 0.009227 0.41835 13.6187
513 3G5S FAD 0.009973 0.41678 13.6187
514 5L95 AMP 0.001665 0.429 13.9785
515 3GU3 SAH 0.000006497 0.49057 14.0078
516 3TLJ SAH 0.00003342 0.4647 14.0078
517 5JCA FAD 0.01634 0.41148 14.0078
518 5JCA NDP 0.03505 0.40769 14.0078
519 4J56 FAD 0.01565 0.41409 14.0351
520 5N5D SAM 0.001137 0.43616 14.1593
521 5THZ SAH 0.000004087 0.54923 14.3969
522 5THY SAH 0.000003165 0.54915 14.3969
523 1G55 SAH 0.00002356 0.49722 14.3969
524 5FTW SAH 0.00006223 0.49296 14.4531
525 4FZV SAM 0.000003268 0.54855 14.6444
526 1U1I NAD 0.01781 0.40193 14.786
527 1NNU TCT 0.04249 0.41192 15
528 5GM1 SAH 0.000001075 0.57469 15.1751
529 5HJM MTA 0.00008516 0.47347 15.1751
530 4YSX FAD 0.003307 0.44224 15.1751
531 5JWC FAD 0.01244 0.41021 15.1751
532 5JE0 AZ8 0.0000009827 0.59179 15.3846
533 5JE0 SAH 0.0000009827 0.59179 15.3846
534 3RNM FAD 0.003937 0.44163 15.5172
535 1Q9I TEO 0.006536 0.44093 15.5642
536 3A4T SFG 0.00003582 0.50565 15.9533
537 3M6W SAM 0.001434 0.41973 15.9533
538 1LSS NAD 0.0002202 0.46912 16.4286
539 5DLY 5D7 0.00001453 0.55115 17.5097
540 5DLY SAH 0.00001261 0.55115 17.5097
541 4USQ FAD 0.007156 0.42019 17.5097
542 2YX1 SFG 0.00008472 0.4626 17.8988
543 2NXE SAM 0.0003135 0.4581 18.1102
544 3EGV SAH 0.0007753 0.44557 18.1102
545 3PFG TLO 0.0000181 0.54805 18.2879
546 3PFG SAM 0.005713 0.45927 18.2879
547 4PNE SAH 0.000003566 0.55182 18.677
548 2EJU SAH 0.00001585 0.51372 18.677
549 5T67 JHZ 0.0006778 0.47975 18.677
550 5T67 SAH 0.0005225 0.47975 18.677
551 2I7C AAT 0.00007021 0.51086 19.0661
552 2PT9 2MH 0.00009875 0.50556 19.0661
553 2PT9 S4M 0.00005436 0.50389 19.0661
554 1WG8 SAM 0.0002726 0.471 19.0661
555 1QZZ SAM 0.0001698 0.45437 19.0661
556 3TKA SAM 0.0006018 0.45015 19.0661
557 3LAD FAD 0.01499 0.41325 19.0661
558 4KRI SAH 0.000001044 0.57007 19.4553
559 1D4D FAD 0.005613 0.43435 19.4553
560 4YUW S4M 0.0001227 0.54977 19.8444
561 4YUW 4JU 0.0001325 0.54859 19.8444
562 1ZEM NAD 0.001339 0.44376 19.8444
563 4R6W PC 0.00007025 0.53277 20.6226
564 4R6W SAH 0.00002564 0.52923 20.6226
565 2PWY SAH 0.0000317 0.51015 21.7054
566 5MGZ SAH 0.0000001559 0.60298 21.7899
567 3L9W AMP 0.0002123 0.48594 22.179
568 3L9W GSH 0.0009094 0.45437 22.179
569 1JQ3 AAT 0.00002018 0.42305 24.1245
570 5M58 SAH 0.00000008821 0.61366 24.3478
571 4IWN GEK 0.0000001934 0.60741 24.4541
572 1VE3 SAM 0.000009278 0.52371 24.6696
573 5E1M PRO PRO LYS ARG ILE ALA 0.00001045 0.55029 25.3112
574 5E1M SAH 0.00001045 0.55029 25.3112
575 4QTU SAM 0.000002554 0.53639 25.9615
576 5JGL SAM 0.000002616 0.53974 28.7938
577 5MPT SAH 0.000009456 0.52335 30.7393
578 5E8J SAH 0.000002234 0.52351 38.6364
Pocket No.: 2; Query (leader) PDB : 4OBW; Ligand: SAM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4obw.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4OBW; Ligand: SAM; Similar sites found: 25
This union binding pocket(no: 3) in the query (biounit: 4obw.bio2) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5AOA PPI 0.0314 0.41249 1.16732
2 2C7G ODP 0.0186 0.4117 2.72374
3 1GV0 NAD 0.01144 0.40004 2.72374
4 2GN3 MMA 0.006578 0.43682 2.77778
5 4D04 NAP 0.02212 0.4127 3.11284
6 4D04 FAD 0.02212 0.4127 3.11284
7 4D42 W0I 0.01745 0.4101 3.11284
8 4D42 NAP 0.01745 0.4101 3.11284
9 1GZ6 NAI 0.0003327 0.4045 3.1348
10 2Q1S NAI 0.01792 0.40473 3.50195
11 1MO9 FAD 0.03931 0.40809 3.82409
12 1MO9 KPC 0.0441 0.40608 3.82409
13 4E70 N7I 0.0003522 0.40562 3.89105
14 1V35 NAI 0.01078 0.41301 4.28016
15 1UXG NAD 0.01449 0.40435 4.28016
16 3LZW NAP 0.0195 0.41276 4.66926
17 3AD8 FAD 0.01073 0.42955 5.05051
18 3AD8 PYC 0.01073 0.42955 5.05051
19 2VHL GLP 0.01604 0.40537 5.05837
20 2RAB FAD 0.0115 0.41442 5.44747
21 5THQ NDP 0.006939 0.40951 6.22568
22 2EXX NAP 0.01378 0.40117 7.393
23 1N4W FAD 0.00481 0.4308 8.94942
24 2J5V PCA 0.01056 0.4163 13.6187
25 1NNU NAD 0.01898 0.42364 15
Pocket No.: 4; Query (leader) PDB : 4OBW; Ligand: SAM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4obw.bio2) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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