Receptor
PDB id Resolution Class Description Source Keywords
4OAV 2.1 Å EC: 7.-.-.- COMPLETE HUMAN RNASE L IN COMPLEX WITH 2-5A (5'-PPP HEPTAMER AND RNA SUBSTRATE. HOMO SAPIENS HPC1 2-5A 2-prime 5-prime -OLIGOADENYLATE INTERFERON DSRNA KINASERIDD IRE1 RNA DECAY RNASE L PROTEIN KINASE PSEUDOKINASEDOMAIN CONTAINING REGULATED RNA DECAY INNATE IMMUNE RESPOANTIVIRAL RESPONSE DSRNA RESPONSE 2-prime 5-prime -LINKED OLIGOADENYRNA HYDROLASE-RNA COMPLEX
Ref.: STRUCTURE OF HUMAN RNASE L REVEALS THE BASIS FOR RE RNA DECAY IN THE IFN RESPONSE. SCIENCE V. 343 1244 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG D:1003;
D:1002;
B:802;
B:803;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
PO4 PO4 A A A A PO4 A:1;
C:1;
Valid;
Valid;
none;
none;
submit data
1565.72 n/a P(=O)...
ACP D:1001;
B:801;
Valid;
Valid;
none;
none;
submit data
505.208 C11 H18 N5 O12 P3 c1nc(...
PUP D:1004;
Valid;
none;
submit data
520.276 C14 H22 N2 O15 P2 C1[C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4OAV 2.1 Å EC: 7.-.-.- COMPLETE HUMAN RNASE L IN COMPLEX WITH 2-5A (5'-PPP HEPTAMER AND RNA SUBSTRATE. HOMO SAPIENS HPC1 2-5A 2-prime 5-prime -OLIGOADENYLATE INTERFERON DSRNA KINASERIDD IRE1 RNA DECAY RNASE L PROTEIN KINASE PSEUDOKINASEDOMAIN CONTAINING REGULATED RNA DECAY INNATE IMMUNE RESPOANTIVIRAL RESPONSE DSRNA RESPONSE 2-prime 5-prime -LINKED OLIGOADENYRNA HYDROLASE-RNA COMPLEX
Ref.: STRUCTURE OF HUMAN RNASE L REVEALS THE BASIS FOR RE RNA DECAY IN THE IFN RESPONSE. SCIENCE V. 343 1244 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 4OAV - PO4 PO4 A A A A PO4 n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 4OAV - PO4 PO4 A A A A PO4 n/a n/a
2 4O1P - 25L C30 H40 N15 O25 P5 c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 4OAV - PO4 PO4 A A A A PO4 n/a n/a
2 4O1P - 25L C30 H40 N15 O25 P5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PO4 PO4 A A A A PO4; Similar ligands found: 148
No: Ligand ECFP6 Tc MDL keys Tc
1 PO4 PO4 A A A A PO4 1 1
2 ADP PO3 0.696629 0.956522
3 ATP A A A 0.686869 0.971014
4 A2P 0.611111 0.942029
5 ATR 0.606383 0.928571
6 NMN AMP PO4 0.605263 0.905405
7 AR6 AR6 0.598131 0.957143
8 N01 0.589744 0.943662
9 ALF ADP 0.565657 0.88
10 ADP ALF 0.565657 0.88
11 A22 0.564356 0.916667
12 VO4 ADP 0.56 0.916667
13 ADP VO4 0.56 0.916667
14 ADP BMA 0.557692 0.930556
15 A2R 0.554455 0.890411
16 25A 0.543689 0.929577
17 A A 0.537736 0.929577
18 2AM 0.533333 0.901408
19 NA7 0.528302 0.866667
20 25L 0.527778 0.916667
21 OVE 0.516129 0.864865
22 ABM 0.505263 0.876712
23 NAP 0.503937 0.930556
24 V3L 0.5 0.902778
25 GAP 0.5 0.90411
26 A A A 0.5 0.916667
27 ADP 0.489796 0.902778
28 A2D 0.489583 0.929577
29 A 0.489362 0.901408
30 AMP 0.489362 0.901408
31 TAP 0.488372 0.893333
32 AN2 0.484848 0.890411
33 NA0 0.484615 0.917808
34 AGS 0.480392 0.855263
35 SAP 0.480392 0.855263
36 M33 0.48 0.890411
37 A12 0.479592 0.866667
38 BA3 0.479592 0.929577
39 AP2 0.479592 0.866667
40 AF3 ADP 3PG 0.478992 0.846154
41 AHZ 0.478632 0.825
42 DAL AMP 0.476636 0.916667
43 B4P 0.474747 0.929577
44 AP5 0.474747 0.929577
45 7D5 0.473118 0.837838
46 NZQ 0.471545 0.846154
47 APC 0.470588 0.866667
48 2A5 0.470588 0.853333
49 AT4 0.47 0.866667
50 7D3 0.469388 0.84
51 SRA 0.46875 0.853333
52 PAP 0.466019 0.915493
53 A3P 0.464646 0.928571
54 4TA 0.464 0.8375
55 NDP 0.463415 0.857143
56 NPW 0.463415 0.825
57 ATP 0.460784 0.902778
58 ACP 0.460784 0.878378
59 50T 0.460784 0.864865
60 HEJ 0.460784 0.902778
61 MYR AMP 0.460177 0.825
62 TXP 0.459677 0.857143
63 A U 0.459016 0.905405
64 ACQ 0.457143 0.878378
65 APR 0.456311 0.902778
66 AR6 0.456311 0.902778
67 5FA 0.456311 0.902778
68 AQP 0.456311 0.902778
69 NJP 0.456 0.905405
70 ODP 0.456 0.87013
71 A G 0.452381 0.893333
72 G A A A 0.452381 0.881579
73 AD9 0.451923 0.878378
74 ADV 0.451923 0.866667
75 RBY 0.451923 0.866667
76 CA0 0.45098 0.878378
77 ADX 0.45098 0.8125
78 7D4 0.45098 0.84
79 AU1 0.45098 0.878378
80 U A G G 0.448819 0.893333
81 3AM 0.447917 0.887324
82 9X8 0.446429 0.855263
83 6YZ 0.444444 0.878378
84 TYR AMP 0.444444 0.905405
85 TAT 0.443396 0.866667
86 T99 0.443396 0.866667
87 ANP 0.443396 0.878378
88 LMS 0.443299 0.790123
89 PRX 0.442308 0.853333
90 U A 0.44186 0.893333
91 ADQ 0.441441 0.90411
92 XNP 0.440945 0.835443
93 AMP NAD 0.440945 0.943662
94 BIS 0.438596 0.844156
95 RAB 0.438202 0.802817
96 ADN 0.438202 0.802817
97 XYA 0.438202 0.802817
98 ARG AMP 0.436975 0.814815
99 ATF 0.435185 0.866667
100 OAD 0.433628 0.878378
101 Z5A 0.432836 0.807229
102 AMP DBH 0.432203 0.90411
103 U A C C 0.430769 0.893333
104 A C A C 0.430769 0.881579
105 NAJ PZO 0.430769 0.881579
106 APC G U 0.430769 0.868421
107 NAD 0.429688 0.943662
108 5N5 0.428571 0.777778
109 NAJ PYZ 0.428571 0.8375
110 SON 0.427184 0.866667
111 LPA AMP 0.42623 0.825
112 PPS 0.425926 0.8125
113 5AL 0.425926 0.890411
114 7MD 0.425 0.802469
115 MAP 0.423423 0.855263
116 1DG 0.422222 0.857143
117 DG1 0.422222 0.857143
118 AV2 0.422018 0.876712
119 AOC 0.42 0.805556
120 5SV 0.419643 0.810127
121 SRP 0.418182 0.866667
122 5AS 0.417476 0.744186
123 A3R 0.415929 0.844156
124 4AD 0.415929 0.88
125 AMO 0.415929 0.866667
126 A1R 0.415929 0.844156
127 PAJ 0.415929 0.822785
128 3OD 0.413793 0.878378
129 FYA 0.413793 0.890411
130 AFH 0.413223 0.846154
131 A3D 0.412214 0.930556
132 U A A U 0.408759 0.893333
133 7L1 0.408759 0.722222
134 A4D 0.408602 0.777778
135 5CD 0.408602 0.788732
136 8QN 0.40708 0.890411
137 OOB 0.40708 0.916667
138 9ZA 0.40708 0.844156
139 9ZD 0.40708 0.844156
140 JB6 0.401709 0.868421
141 NB8 0.401709 0.833333
142 PTJ 0.401709 0.833333
143 1ZZ 0.401709 0.802469
144 PAX 0.40146 0.8375
145 DLL 0.4 0.916667
146 AHX 0.4 0.833333
147 00A 0.4 0.868421
148 NAE 0.4 0.905405
Ligand no: 2; Ligand: ACP; Similar ligands found: 368
No: Ligand ECFP6 Tc MDL keys Tc
1 ACP 1 1
2 ACQ 0.866667 1
3 A2D 0.857143 0.945205
4 6YZ 0.833333 1
5 BA3 0.833333 0.945205
6 AP5 0.821918 0.945205
7 B4P 0.821918 0.945205
8 ADP 0.821918 0.972222
9 AT4 0.810811 0.933333
10 AN2 0.810811 0.958904
11 AP2 0.808219 0.986301
12 A12 0.808219 0.986301
13 M33 0.8 0.932432
14 HEJ 0.789474 0.972222
15 ATP 0.789474 0.972222
16 5FA 0.779221 0.972222
17 AR6 0.779221 0.945205
18 AQP 0.779221 0.972222
19 APR 0.779221 0.945205
20 AGS 0.769231 0.921053
21 SAP 0.769231 0.921053
22 AD9 0.769231 0.945946
23 AMP 0.763889 0.944444
24 A 0.763889 0.944444
25 APC 0.75641 0.986301
26 CA0 0.753247 0.92
27 ADX 0.753247 0.851852
28 ANP 0.75 0.945946
29 50T 0.74359 0.932432
30 PRX 0.734177 0.87013
31 ABM 0.733333 0.893333
32 ATF 0.731707 0.933333
33 SRA 0.706667 0.894737
34 A22 0.705882 0.958904
35 RBY 0.703704 0.959459
36 ADV 0.703704 0.959459
37 5AL 0.698795 0.906667
38 A3R 0.689655 0.909091
39 A1R 0.689655 0.909091
40 ADQ 0.689655 0.92
41 AU1 0.6875 0.945946
42 TAT 0.686747 0.933333
43 T99 0.686747 0.933333
44 SRP 0.682353 0.907895
45 9X8 0.674157 0.896104
46 OAD 0.674157 0.92
47 4TC 0.673469 0.922078
48 4AD 0.670455 0.921053
49 AMO 0.670455 0.933333
50 00A 0.662921 0.860759
51 ADP PO3 0.662651 0.917808
52 3OD 0.659341 0.92
53 BIS 0.659341 0.909091
54 25A 0.659091 0.945205
55 OOB 0.659091 0.906667
56 8QN 0.659091 0.906667
57 5SV 0.659091 0.82716
58 SON 0.654321 0.933333
59 25L 0.652174 0.958904
60 PAJ 0.651685 0.8625
61 DLL 0.644444 0.906667
62 AHX 0.644444 0.897436
63 TXA 0.641304 0.907895
64 3UK 0.637363 0.894737
65 ALF ADP 0.632184 0.848101
66 ADP ALF 0.632184 0.848101
67 PR8 0.630435 0.851852
68 WAQ 0.630435 0.884615
69 B5V 0.630435 0.883117
70 LAD 0.630435 0.8625
71 MAP 0.629214 0.921053
72 LMS 0.628205 0.807229
73 GAP 0.627907 0.87013
74 VO4 ADP 0.625 0.906667
75 ADP VO4 0.625 0.906667
76 PTJ 0.623656 0.873418
77 FYA 0.623656 0.906667
78 ME8 0.623656 0.841463
79 1ZZ 0.623656 0.819277
80 NB8 0.623656 0.897436
81 UP5 0.62 0.896104
82 G3A 0.618557 0.897436
83 G5P 0.612245 0.897436
84 AFH 0.612245 0.886076
85 9SN 0.610526 0.85
86 DQV 0.606061 0.932432
87 GTA 0.606061 0.864198
88 9ZD 0.604396 0.884615
89 9ZA 0.604396 0.884615
90 YAP 0.604167 0.896104
91 FA5 0.604167 0.907895
92 B5Y 0.604167 0.871795
93 B5M 0.604167 0.871795
94 TXD 0.60396 0.884615
95 XAH 0.597938 0.841463
96 ADN 0.597222 0.821918
97 RAB 0.597222 0.821918
98 XYA 0.597222 0.821918
99 GA7 0.59596 0.907895
100 48N 0.594059 0.897436
101 DAL AMP 0.593407 0.881579
102 2A5 0.593023 0.92
103 AOC 0.592593 0.8
104 4UV 0.591837 0.871795
105 NXX 0.588235 0.907895
106 6V0 0.588235 0.873418
107 NAX 0.588235 0.875
108 DND 0.588235 0.907895
109 NAI 0.588235 0.884615
110 ATR 0.586207 0.944444
111 PAP 0.586207 0.958333
112 ADP BMA 0.585106 0.894737
113 LAQ 0.584158 0.819277
114 5AS 0.583333 0.761364
115 OMR 0.582524 0.831325
116 TXE 0.582524 0.884615
117 5N5 0.581081 0.797297
118 4UU 0.58 0.871795
119 A A 0.578947 0.918919
120 7D3 0.578313 0.881579
121 AP0 0.576923 0.873418
122 A4D 0.573333 0.797297
123 5CD 0.573333 0.783784
124 JB6 0.572917 0.884615
125 4UW 0.572816 0.839506
126 A4P 0.571429 0.823529
127 CNA 0.570093 0.907895
128 ITT 0.569767 0.917808
129 7D4 0.569767 0.881579
130 A2R 0.565217 0.958904
131 M2T 0.564103 0.716049
132 YLP 0.563107 0.821429
133 139 0.560748 0.851852
134 ADJ 0.560748 0.831325
135 T5A 0.560748 0.843373
136 TAD 0.558824 0.910256
137 ATP A A A 0.555556 0.905405
138 A3P 0.552941 0.944444
139 TYM 0.552381 0.907895
140 IOT 0.551402 0.833333
141 EP4 0.551282 0.734177
142 MYR AMP 0.55102 0.797619
143 F2R 0.550459 0.865854
144 7D5 0.55 0.855263
145 A3D 0.54955 0.894737
146 80F 0.54955 0.843373
147 GCP 0.548387 0.922078
148 UPA 0.54717 0.884615
149 YLC 0.54717 0.841463
150 YLB 0.54717 0.821429
151 NAD 0.545455 0.906667
152 COD 0.545455 0.813953
153 G5A 0.544444 0.781609
154 HFD 0.544444 0.921053
155 DTA 0.544304 0.766234
156 3DH 0.54321 0.753247
157 DZD 0.540541 0.910256
158 AHZ 0.538462 0.797619
159 MTA 0.5375 0.753247
160 3AM 0.536585 0.90411
161 A2P 0.534884 0.930556
162 AR6 AR6 0.533981 0.893333
163 PPS 0.532609 0.851852
164 6AD 0.532609 0.886076
165 YLA 0.53211 0.821429
166 TYR AMP 0.529412 0.871795
167 AMP DBH 0.529412 0.87013
168 AYB 0.527273 0.811765
169 A5A 0.526882 0.788235
170 TSB 0.526316 0.8
171 6RE 0.52381 0.7625
172 S4M 0.523256 0.670455
173 SSA 0.521277 0.802326
174 NA7 0.520408 0.959459
175 7MD 0.519231 0.864198
176 ARG AMP 0.519231 0.831325
177 LPA AMP 0.518868 0.797619
178 BTX 0.517857 0.843373
179 NAE 0.517241 0.871795
180 54H 0.515789 0.770115
181 52H 0.515789 0.761364
182 VMS 0.515789 0.770115
183 BT5 0.513274 0.833333
184 NAQ 0.512821 0.85
185 ZAS 0.511905 0.746835
186 J7C 0.511628 0.772152
187 A3N 0.511628 0.766234
188 IMO 0.511628 0.90411
189 AV2 0.510638 0.893333
190 53H 0.510417 0.761364
191 8X1 0.510417 0.755556
192 5CA 0.510417 0.802326
193 ARU 0.510204 0.839506
194 AF3 ADP 3PG 0.509259 0.839506
195 M24 0.508621 0.829268
196 ZID 0.508475 0.894737
197 2AM 0.506024 0.917808
198 V3L 0.505376 0.945205
199 3AT 0.505376 0.972222
200 AVV 0.505155 0.897436
201 NSS 0.5 0.802326
202 EAD 0.5 0.851852
203 DSZ 0.5 0.802326
204 MAO 0.5 0.761905
205 LSS 0.5 0.764045
206 DSH 0.5 0.728395
207 P5A 0.5 0.747253
208 YLY 0.495726 0.811765
209 9K8 0.49505 0.698925
210 NVA LMS 0.494949 0.755556
211 DAT 0.494505 0.906667
212 5X8 0.494505 0.766234
213 AMP NAD 0.491228 0.881579
214 7MC 0.490909 0.843373
215 LEU LMS 0.49 0.755556
216 SMM 0.489583 0.689655
217 SAM 0.489362 0.694118
218 DTP 0.489362 0.906667
219 7DD 0.488889 0.958333
220 GJV 0.488636 0.753086
221 OVE 0.488372 0.881579
222 5AD 0.486842 0.726027
223 GSU 0.485149 0.781609
224 KAA 0.485149 0.755556
225 P1H 0.483871 0.831325
226 NDE 0.483871 0.907895
227 N0B 0.483333 0.821429
228 A3G 0.482759 0.802632
229 NAJ PZO 0.478632 0.82716
230 4TA 0.478261 0.809524
231 SFG 0.478261 0.753247
232 NDC 0.47619 0.85
233 YSA 0.47619 0.781609
234 FB0 0.47619 0.827586
235 7DT 0.473118 0.958333
236 A7D 0.472527 0.779221
237 NJP 0.469565 0.921053
238 FDA 0.46875 0.835294
239 SA8 0.468085 0.710843
240 A5D 0.468085 0.766234
241 MHZ 0.467391 0.701149
242 8PZ 0.466667 0.802326
243 71V 0.466667 0.884615
244 G A A A 0.465517 0.85
245 0WD 0.465517 0.897436
246 6FA 0.465116 0.843373
247 GGZ 0.464646 0.804878
248 SAI 0.463158 0.7375
249 SAH 0.463158 0.746835
250 6C6 0.463158 0.883117
251 NAJ PYZ 0.46281 0.788235
252 Y3J 0.4625 0.706667
253 7D7 0.461538 0.723684
254 TXP 0.46087 0.897436
255 PO4 PO4 A A A A PO4 0.460784 0.878378
256 S7M 0.459184 0.694118
257 6IA 0.458333 0.839506
258 DDS 0.458333 0.855263
259 FAS 0.458015 0.853659
260 FAD 0.458015 0.853659
261 SFD 0.458015 0.736842
262 ODP 0.456897 0.886076
263 A3S 0.456522 0.813333
264 U A 0.453782 0.884615
265 7C5 0.453704 0.797468
266 EEM 0.453608 0.694118
267 AAT 0.453608 0.710843
268 A G 0.452991 0.860759
269 RGT 0.45283 0.933333
270 NPW 0.452174 0.8875
271 NDP 0.452174 0.897436
272 FAY 0.451852 0.864198
273 PGS 0.451613 0.860759
274 D5M 0.449438 0.88
275 DA 0.449438 0.88
276 NEC 0.449438 0.727273
277 U A G G 0.449153 0.860759
278 2SA 0.44898 0.933333
279 NIA 0.448276 0.802469
280 NZQ 0.448276 0.910256
281 A U 0.447368 0.848101
282 A3T 0.446809 0.8
283 A A A 0.446602 0.906667
284 128 0.446429 0.758621
285 6K6 0.445545 0.905405
286 GEK 0.445545 0.740741
287 4YB 0.445455 0.764045
288 AAM 0.444444 0.944444
289 FNK 0.444444 0.806818
290 62F 0.444444 0.864198
291 Z5A 0.443548 0.761364
292 WSA 0.442478 0.790698
293 AMZ 0.44186 0.891892
294 C2R 0.44186 0.88
295 12D 0.441441 0.767442
296 XNP 0.440678 0.851852
297 RFL 0.437956 0.823529
298 62X 0.436893 0.670455
299 N6P 0.436893 0.890411
300 AIR 0.433735 0.876712
301 GP3 0.43299 0.897436
302 A6D 0.432692 0.705882
303 V1N 0.431193 0.893333
304 649 0.429825 0.747253
305 GP2 0.428571 0.910256
306 GDP 0.428571 0.896104
307 NA0 0.428571 0.907895
308 0UM 0.427184 0.702381
309 ETB 0.42623 0.835294
310 DCA 0.42623 0.825581
311 8Q2 0.426087 0.775281
312 9JJ 0.425532 0.841463
313 GNH 0.424242 0.884615
314 NAP 0.424 0.92
315 PUA 0.422764 0.8625
316 APU 0.422414 0.871795
317 101 0.422222 0.855263
318 3AD 0.421687 0.808219
319 FA9 0.42069 0.865854
320 TAP 0.420635 0.884615
321 TM1 0.420561 0.755814
322 P5F 0.41958 0.825581
323 0T1 0.419355 0.825581
324 COA 0.419355 0.825581
325 K15 0.419048 0.686047
326 7RP 0.417582 0.902778
327 S8M 0.417476 0.7625
328 NHD 0.416667 0.881579
329 GTP 0.415842 0.896104
330 FCX 0.414062 0.797753
331 F2N 0.413793 0.816092
332 AS 0.413043 0.835443
333 7RA 0.413043 0.931507
334 G1R 0.411765 0.884615
335 SXZ 0.411215 0.714286
336 ACK 0.411111 0.837838
337 QQY 0.411111 0.794872
338 CAO 0.409449 0.797753
339 COS 0.409449 0.806818
340 DG1 0.409449 0.897436
341 30N 0.409449 0.755319
342 AMX 0.409449 0.835294
343 1DG 0.409449 0.897436
344 J7V 0.409449 0.813953
345 EO7 0.408602 0.770115
346 8BR 0.408602 0.883117
347 NVA 2AD 0.408163 0.7625
348 D3Y 0.407767 0.792208
349 GSP 0.407767 0.851852
350 9GM 0.407767 0.873418
351 GNP 0.407767 0.873418
352 G2P 0.407767 0.910256
353 CC5 0.407407 0.819444
354 KB1 0.407407 0.702381
355 N01 0.406504 0.881579
356 A C A C 0.406504 0.82716
357 SCO 0.40625 0.825581
358 CMX 0.40625 0.825581
359 HDV 0.405941 0.87013
360 CMP 0.404255 0.876712
361 2BA 0.404255 0.890411
362 ACO 0.403101 0.797753
363 FAM 0.403101 0.806818
364 2VA 0.402062 0.779221
365 3NZ 0.401869 0.78481
366 HAX 0.4 0.806818
367 QQX 0.4 0.78481
368 26A 0.4 0.74359
Ligand no: 3; Ligand: PUP; Similar ligands found: 51
No: Ligand ECFP6 Tc MDL keys Tc
1 PUP 1 1
2 UPU 0.629214 0.913043
3 UA3 0.625 0.940298
4 U3P 0.625 0.940298
5 APU 0.581818 0.831169
6 U2P 0.511628 0.926471
7 UDX 0.495146 0.887324
8 UAD 0.495146 0.887324
9 UDP 0.48913 0.913043
10 UMF 0.488636 0.859155
11 U U U U 0.485149 0.913043
12 GUD 0.480392 0.887324
13 UTP U U U 0.480392 0.869565
14 GDU 0.480392 0.887324
15 UPG 0.480392 0.887324
16 UFM 0.480392 0.887324
17 UTP 0.473684 0.913043
18 U5P 0.47191 0.926471
19 U 0.47191 0.926471
20 UCG 0.46875 0.777778
21 UPF 0.466667 0.84
22 U2F 0.466667 0.84
23 URM 0.466019 0.928571
24 660 0.466019 0.928571
25 UNP 0.459184 0.887324
26 CJB 0.458824 0.771429
27 URI 0.457831 0.811594
28 U U 0.457143 0.9
29 UFG 0.45283 0.84
30 44P 0.44086 0.928571
31 G3N 0.440367 0.863014
32 2KH 0.438776 0.887324
33 CSV 0.4375 0.828947
34 UDM 0.4375 0.915493
35 CSQ 0.4375 0.828947
36 U2G 0.434426 0.780488
37 USQ 0.431193 0.777778
38 UD1 0.429825 0.875
39 UD2 0.429825 0.875
40 UPA 0.429752 0.797468
41 UPP 0.428571 0.861111
42 DKX 0.426966 0.726027
43 3UC 0.423423 0.84
44 Y6W 0.420561 0.916667
45 UDH 0.415094 0.891892
46 UDP UDP 0.412371 0.884058
47 DUD 0.408163 0.942029
48 UGA 0.405405 0.873239
49 UGB 0.405405 0.873239
50 DU 0.4 0.955882
51 UMP 0.4 0.955882
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4OAV; Ligand: ACP; Similar sites found with APoc: 6
This union binding pocket(no: 1) in the query (biounit: 4oav.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 3RWP ABQ 7.71704
2 2V7O DRN 9.82143
3 4WNP 3RJ 10.8014
4 4NM5 ADP 12.5
5 3DAK ANP 22.069
6 2RIO ADP 38.7097
Pocket No.: 2; Query (leader) PDB : 4OAV; Ligand: PUP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4oav.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4OAV; Ligand: PO4 PO4 A A A A PO4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4oav.bio1) has 33 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4OAV; Ligand: PO4 PO4 A A A A PO4; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4oav.bio1) has 31 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4OAV; Ligand: ACP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 4oav.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
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