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Receptor
PDB id Resolution Class Description Source Keywords
4NCN 1.87 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF EUKARYOTIC TRANSLATION INITIATION FACTO (517-858) FROM CHAETOMIUM THERMOPHILUM IN COMPLEX WITH GTP CHAETOMIUM THERMOPHILUM VAR. THERMOPHIORGANISM_TAXID: 759272 TRANSLATION INITIATION GTPASE EIF5B/IF2 SUBUNIT JOINING TRANSLATION
Ref.: EIF5B EMPLOYS A NOVEL DOMAIN RELEASE MECHANISM TO C RIBOSOMAL SUBUNIT JOINING. EMBO J. V. 33 1177 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GTP A:1001;
B:1001;
Valid;
Valid;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
GOL B:1006;
B:1005;
A:1006;
A:1004;
A:1005;
B:1007;
B:1008;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
NA A:1003;
B:1003;
Part of Protein;
Part of Protein;
none;
none;
submit data
22.99 Na [Na+]
MG A:1002;
B:1002;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ACY B:1004;
Invalid;
none;
submit data
60.052 C2 H4 O2 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4NCN 1.87 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF EUKARYOTIC TRANSLATION INITIATION FACTO (517-858) FROM CHAETOMIUM THERMOPHILUM IN COMPLEX WITH GTP CHAETOMIUM THERMOPHILUM VAR. THERMOPHIORGANISM_TAXID: 759272 TRANSLATION INITIATION GTPASE EIF5B/IF2 SUBUNIT JOINING TRANSLATION
Ref.: EIF5B EMPLOYS A NOVEL DOMAIN RELEASE MECHANISM TO C RIBOSOMAL SUBUNIT JOINING. EMBO J. V. 33 1177 2014
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 291 families.
1 4NCN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4NCL - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4NCN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4NCL - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4TMX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 4TMZ Kd = 0.92 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4TMV - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
6 4TMT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
7 4TMW Kd = 4.1 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4NCN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 4NCL - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4TMX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 4TMZ Kd = 0.92 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4TMV - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
6 4TMT - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
7 4TMW Kd = 4.1 uM GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 156
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 9GM 0.809524 0.973684
9 GNP 0.809524 0.973684
10 GCP 0.797619 0.973684
11 5GP 0.797468 0.986486
12 G 0.797468 0.986486
13 GMV 0.764706 0.973684
14 G2R 0.764045 0.961039
15 G5P 0.755319 0.973684
16 GTG 0.752688 0.936709
17 G2P 0.747126 0.961039
18 G3A 0.744681 0.973684
19 GDD 0.741935 0.961039
20 GDC 0.741935 0.961039
21 GKE 0.741935 0.961039
22 0O2 0.736264 0.986486
23 GP2 0.729412 0.961039
24 6CK 0.726316 0.936709
25 Y9Z 0.723404 0.902439
26 GPG 0.717391 0.961039
27 GFB 0.715789 0.961039
28 GDR 0.715789 0.961039
29 GPD 0.704082 0.925
30 GKD 0.693878 0.961039
31 JB2 0.693878 0.961039
32 GDX 0.686869 0.973684
33 ALF 5GP 0.685393 0.888889
34 GH3 0.681319 0.973333
35 YGP 0.677083 0.901235
36 G3D 0.67033 0.986486
37 GDP AF3 0.659574 0.888889
38 ALF GDP 0.659574 0.888889
39 GDP ALF 0.659574 0.888889
40 DGT 0.659341 0.923077
41 GMP 0.658228 0.88
42 G4P 0.655914 0.986486
43 JB3 0.653846 0.948718
44 NGD 0.647619 0.961039
45 CAG 0.642202 0.880952
46 2MD 0.62963 0.891566
47 MGP 0.619565 0.961039
48 U2G 0.616822 0.936709
49 6G0 0.612903 0.961039
50 MGD 0.612613 0.891566
51 TPG 0.608696 0.840909
52 CG2 0.605505 0.936709
53 GDP 7MG 0.601942 0.911392
54 FEG 0.601852 0.879518
55 G G 0.598039 0.948052
56 ZGP 0.59633 0.869048
57 PGD 0.591304 0.925
58 MD1 0.591304 0.891566
59 3GP 0.590909 0.946667
60 GPX 0.581633 0.946667
61 DGI 0.580645 0.923077
62 IDP 0.576087 0.972973
63 DBG 0.567797 0.948718
64 2GP 0.555556 0.96
65 FE9 0.555556 0.776596
66 G4M 0.547619 0.880952
67 BGO 0.544643 0.924051
68 GCP G 0.543689 0.921053
69 ATP 0.537634 0.92
70 HEJ 0.537634 0.92
71 G1G 0.533898 0.925
72 AQP 0.531915 0.92
73 5FA 0.531915 0.92
74 A G 0.525862 0.935065
75 G A A A 0.525862 0.923077
76 U A G G 0.521368 0.935065
77 HFD 0.520833 0.873418
78 R5I 0.520408 0.946667
79 R7I 0.520408 0.946667
80 01G 0.518868 0.902439
81 P2G 0.510638 0.883117
82 ITT 0.510638 0.868421
83 AKW 0.504348 0.890244
84 GGM 0.504274 0.901235
85 G1R G1R 0.504065 0.924051
86 DGP 0.5 0.910256
87 PGD O 0.5 0.850575
88 MGO 0.5 0.864198
89 DG 0.5 0.910256
90 P1G 0.5 0.871795
91 GTA 0.495495 0.936709
92 PRT 0.490741 0.959459
93 B4P 0.489362 0.894737
94 AP5 0.489362 0.894737
95 IMP 0.489362 0.959459
96 G U 0.487179 0.9
97 7DT 0.484536 0.906667
98 GPC 0.479339 0.879518
99 G C 0.478992 0.9
100 BA3 0.478723 0.894737
101 ADP 0.473684 0.92
102 G2Q 0.471698 0.961039
103 6YZ 0.470588 0.896104
104 G7M 0.46875 0.948052
105 C1Z 0.462963 0.986486
106 25L 0.458716 0.907895
107 A2D 0.457447 0.894737
108 RGT 0.45045 0.909091
109 AGS 0.45 0.873418
110 SAP 0.45 0.873418
111 SGP 0.44898 0.82716
112 A4P 0.445378 0.869048
113 G G G RPC 0.442623 0.875
114 ANP 0.441176 0.896104
115 ACQ 0.441176 0.896104
116 8GT 0.441176 0.875
117 APC G U 0.44 0.886076
118 AT4 0.438776 0.884615
119 G U34 0.438017 0.888889
120 6AD 0.436893 0.841463
121 G G G C 0.433071 0.9125
122 UP5 0.432203 0.873418
123 PCG 0.431373 0.933333
124 C2E 0.431373 0.921053
125 35G 0.431373 0.933333
126 A G C C 0.429688 0.911392
127 T99 0.427184 0.884615
128 5GP 5GP 0.427184 0.883117
129 TAT 0.427184 0.884615
130 AR6 0.425743 0.894737
131 APR 0.425743 0.894737
132 7DD 0.424242 0.906667
133 AN2 0.424242 0.907895
134 DG DG 0.423423 0.865854
135 AD9 0.421569 0.896104
136 M33 0.42 0.883117
137 7D4 0.42 0.835443
138 UCG 0.419847 0.911392
139 HDV 0.419048 0.825
140 H6Y 0.419048 0.946667
141 G C C C 0.416667 0.924051
142 ACP 0.415842 0.896104
143 T5A 0.414634 0.802326
144 A1R 0.412844 0.839506
145 ADQ 0.412844 0.871795
146 MGQ 0.412844 0.935897
147 A3R 0.412844 0.839506
148 MGT 0.411215 0.823529
149 A G U 0.410072 0.888889
150 93A 0.41 0.833333
151 A22 0.407407 0.907895
152 CA0 0.405941 0.896104
153 ATF 0.40566 0.884615
154 AGO 0.404762 0.888889
155 MGV 0.401786 0.890244
156 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4NCN; Ligand: GTP; Similar sites found with APoc: 638
This union binding pocket(no: 1) in the query (biounit: 4ncn.bio2) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 3P4X ADP 0.968523
2 4IDN GNP 1.31291
3 5XDR ADP 1.31291
4 3VM7 GLC 1.31291
5 3LL4 2FP 1.36986
6 5XLS URA 1.37931
7 1V8K ANP 1.46341
8 2FSH ANP 1.53173
9 5KGS 6SR 1.53173
10 1ION ADP 1.64609
11 3MD0 GDP 1.69014
12 1GOJ ADP 1.69014
13 3ZFD ANP 1.7094
14 4YJ1 ADP 1.75055
15 5HR5 ADP 1.75055
16 1MLY ACZ PLP 1.75055
17 4LC1 GDP 1.78042
18 2OWZ CIT 1.80723
19 2AWN ADP 1.83727
20 2HCR AMP 1.84049
21 3ZZH NLG 1.9544
22 2RCN GDP 1.95531
23 1IWE IMP 1.96937
24 1OYY AGS 1.96937
25 6FAA ADP 1.96937
26 1G41 ADP 1.96937
27 5ZXD ATP 1.96937
28 2WOJ ADP ALF 1.9774
29 5L3V GDP 2.00669
30 2CJW GDP 2.08333
31 1VKJ A3P 2.10526
32 1E2K TMC 2.1148
33 4D81 ADP 2.12014
34 1JI0 ATP 2.18818
35 1XP8 AGS 2.18818
36 1LVK MNT BEF 2.18818
37 5BN3 ADP 2.18818
38 4UOX PLP 2.18818
39 3QF7 ANP 2.19178
40 4P4T GDP 2.22222
41 4PVR ASP 2.25806
42 3DEF GDP 2.29008
43 1QF5 GDP 2.32019
44 1QF5 RPL 2.32019
45 4FRZ ADP 2.33161
46 4R43 GDP 2.39617
47 4PFO ADP 2.407
48 4ZDJ UTP 2.407
49 1DNP MHF 2.407
50 1TQ4 GDP 2.42131
51 2ZFI ADP 2.45902
52 2Y65 ADP 2.46575
53 3QXC ATP 2.47934
54 6CBO DOW 2.50569
55 3FVQ ATP 2.50696
56 1K6M AGS 2.5463
57 6B4K ANP 2.55814
58 1W0J ADP 2.57353
59 1W0J ADP BEF 2.57353
60 2ZR9 DTP 2.5788
61 1OFH ADP 2.58065
62 1H65 GDP 2.59259
63 4IHQ ADP 2.62582
64 6EGU 43Y 2.62582
65 2C9O ADP 2.63158
66 5H68 AGS 2.64706
67 1Y63 ADP 2.71739
68 5X40 ACP 2.73973
69 4HSE ADP 2.77078
70 1UJ2 ADP 2.77778
71 1UJ2 C5P 2.77778
72 6AIC AMP 2.80374
73 6B8B ADP 2.81124
74 1F5N GNP 2.84464
75 3BFV ADP 2.84464
76 1X6V ADP 2.85714
77 4U60 SIA 2.85714
78 4GOX A3P 2.8754
79 5U32 GDP 2.9661
80 2PL3 ADP 2.9661
81 4B9E FAH 2.99003
82 2XTN GTP 2.99145
83 3B7G ANP 3.04348
84 2ZPA ADP 3.06346
85 1R6B ADP 3.06346
86 4YDS ATP 3.07018
87 1BG2 ADP 3.07692
88 1FNN ADP 3.08483
89 5MVR ADP 3.08642
90 4V03 ADP 3.11284
91 2VVG ADP 3.14286
92 1R0X ATP 3.14685
93 1VHT BA3 3.21101
94 1ZIN AP5 3.22581
95 2Q2Y ADP 3.26975
96 2Q2Y MKR 3.26975
97 4A4Z ANP 3.28228
98 5AK0 8V1 3.28228
99 2ZJ5 ADP 3.28228
100 1P72 ADP 3.29341
101 1ZCB GDP 3.31492
102 1MR3 G3D 3.31492
103 1RRC ADP 3.32226
104 6DEF GCP 3.32481
105 5JCP GDP ALF 3.34129
106 3E70 GDP 3.35366
107 2OZE AGS 3.3557
108 5LB3 ADP 3.37079
109 3ZQ6 ADP ALF 3.39506
110 2V7Q ATP 3.42466
111 2CK3 ANP 3.42466
112 2CK3 ADP 3.42466
113 2V7Q ADP 3.42466
114 2JFV FLC 3.43643
115 6AU6 GDP 3.44828
116 1SVM ATP 3.44828
117 3IO3 ADP 3.44828
118 2W58 ADP 3.46535
119 5VGR GDP 3.48028
120 3DC4 ADP 3.48837
121 3FKQ ATP 3.50109
122 3FWY ADP 3.50318
123 1LVG ADP 3.53535
124 4XGU ADP 3.53774
125 4WOP CTP 3.55556
126 3TKL GTP 3.57143
127 2J59 GTP 3.61446
128 1O3Y GTP 3.61446
129 4ZNL BEF ADP 3.64964
130 3AB3 GDP 3.65854
131 1SVK ALF GDP 3.68272
132 4NU0 AP5 3.68664
133 3TMK T5A 3.7037
134 3BFX A3P 3.71622
135 4ZG4 VO4 ADP 3.71991
136 5TSH ANP 3.71991
137 5TSH ADP 3.71991
138 2GKS ADP 3.71991
139 4E3Q PMP 3.71991
140 1P4V GLY 3.72881
141 4PX9 ADP 3.76712
142 3TBK ANP 3.78378
143 4WZ6 ATP 3.7931
144 3COB ADP 3.79404
145 3AQ4 GDP 3.80435
146 4Y4V DAL 3.83481
147 3QKT ANP 3.83481
148 5AHO TLA 3.86905
149 1G6H ADP 3.89105
150 2P3V SRT 3.90625
151 2FNA ADP 3.92157
152 3CX8 GSP 3.93873
153 5LTJ BEF 3.93873
154 5LTJ ADP 3.93873
155 1QHG ATP 3.93873
156 1G6O ADP 3.93939
157 1UKZ ADP 3.94089
158 1RJ9 GCP 3.94737
159 1Y3A GDP 3.95137
160 2B8W ALF 5GP 3.96341
161 1OXV ANP 3.96601
162 1W7J ADP BEF 3.97351
163 3NKV GNP 4
164 4PPF FLC 4
165 1FQK GDP 4
166 1FQK ALF 4
167 1AQU A3P 4.0404
168 2NCD ADP 4.04762
169 4AG5 ADP 4.08163
170 2FFQ GSP 4.09357
171 1SVI GDP 4.10256
172 1YZQ GNP 4.11765
173 1QF9 ADP 4.12371
174 1QF9 C5P 4.12371
175 1QF9 ALF 4.12371
176 1BH2 GSP 4.12698
177 5MZN ADP 4.15755
178 2FAH GDP 4.15755
179 1XKV ATP 4.15755
180 1BO4 COA 4.16667
181 1NN5 ANP 4.18605
182 1NN5 2DT 4.18605
183 3Q72 GNP 4.21687
184 1G3Q ADP 4.21941
185 5J1S ATP 4.22535
186 2IYL GDP 4.22535
187 1L2T ATP 4.25532
188 3R7F CP 4.27632
189 4QRH 0O2 4.28571
190 2OBM ADP 4.32277
191 1YZN GNP 4.32432
192 2OFW ADX 4.32692
193 6A20 ADP 4.34783
194 4KVA GTP 4.37637
195 1IHU ADP 4.37637
196 1IHU AF3 4.37637
197 5IRN ADP 4.37637
198 5KSZ GCP 4.48113
199 4U5X GNP 4.49438
200 1FP6 ADP 4.49827
201 5XKT GNP 4.5
202 3TK1 GDP 4.54545
203 1YRB GDP 4.58015
204 1T5C ADP 4.58453
205 2CE7 ADP 4.59519
206 4MKG AP5 4.60829
207 4IOK XPO 4.65116
208 4IOK ADP 4.65116
209 4QM7 GTP 4.67836
210 3H86 AP5 4.6875
211 4WEI GLC GAL 4.69314
212 4WZA ACP 4.71014
213 4WZA ADP 4.71014
214 4BFW ZVW 4.71698
215 3KJI ADP 4.72441
216 3RAB GNP 4.73373
217 1M7G ADX 4.73934
218 1M7G ADP 4.73934
219 1M7G AV2 4.73934
220 3QVV A3P 4.74576
221 5CK5 GDP 4.74684
222 5DQY BEZ 4.7619
223 1G8S MET 4.78261
224 2PZE ATP 4.80349
225 1YQT ADP 4.814
226 3CV2 OXL 4.814
227 5G3Y ADP 4.86726
228 2QQ0 TMP 4.8913
229 2QQ0 ADP 4.8913
230 2QQ0 ANP 4.8913
231 2QQ0 THM 4.8913
232 3NHB ADP 4.90196
233 4KBF AMP 4.93151
234 2CDN ADP 4.97512
235 2DPY ADP 5.02283
236 2PEZ GGZ 5.02793
237 2PEZ DAT 5.02793
238 5I0H ADP BEF 5.03282
239 5WC2 ADP 5.03282
240 2BIF ANP 5.03282
241 2BIF SIN 5.03282
242 4LYA ATP 5.03282
243 5VHC BEF ADP 5.03282
244 2CBZ ATP 5.06329
245 4MKF AP5 5.06912
246 5FHD ADP ALF 5.08083
247 5FTB ANP 5.08083
248 1NJF AGS 5.2
249 1NJF ADP 5.2
250 1PSC EBP 5.20548
251 3SFV GDP 5.23256
252 2D3N GLC GLC GLC 5.25164
253 5M7P ADP 5.25164
254 5H4S RAM 5.28169
255 5UIV ADP 5.28634
256 5BQ5 ADP BEF 5.29101
257 3Q85 GNP 5.32544
258 5ZBR ANP 5.33333
259 2J5V PCA 5.44959
260 2O0J ADP 5.45455
261 1XEX ATP 5.49451
262 3EZ2 ADP 5.52764
263 5N69 ADP 5.52764
264 1S3G AP5 5.52995
265 2G77 GDP 5.55556
266 2G77 AF3 5.55556
267 5L3W GDP 5.55556
268 3FB4 AP5 5.55556
269 4OHY ANP 5.56845
270 4LJ9 ACP 5.60472
271 3E5H GNP 5.61798
272 2XTZ GSP 5.64972
273 4KFU ACP 5.66038
274 5L3S GNP 5.74324
275 5L3S G 5.74324
276 3B5J 12D 5.76132
277 6C90 ADP 5.76923
278 1Z06 GNP 5.82011
279 2X77 GDP 5.82011
280 5G41 AP5 5.8296
281 5M04 GDP 5.83333
282 3T34 GDP 5.83333
283 5IRR GSP 5.84416
284 3EWA ANP 5.90062
285 2IXE ATP 5.90406
286 4H1V GNP 5.9081
287 5IFS ADP 5.9081
288 3HU3 AGS 5.9081
289 2F9L GDP 6.03015
290 2VB6 ADP BEF 6.04027
291 4FCW ADP 6.10932
292 3DKP ADP 6.12245
293 4YS0 ADP 6.12691
294 3REF GDP 6.18557
295 3LRE ADP 6.19718
296 1DS6 GDP 6.25
297 5H67 ATP 6.25
298 4YMU ATP 6.25
299 6CS8 F9Y 6.27063
300 1OIX GDP 6.28272
301 1OIV GDP 6.28272
302 4NE2 SH2 6.28743
303 4NE2 ADP 6.28743
304 4LHW GNP 6.32184
305 3TNF GNP 6.32184
306 2D7D ADP 6.34573
307 2XAU ADP 6.34573
308 4YLG GDP 6.35838
309 6CIB ADP 6.36605
310 1ZD9 GDP 6.38298
311 2GK6 ADP 6.41026
312 6C0B MLI 6.41026
313 3BER AMP 6.4257
314 1KSH GDP 6.45161
315 4DKX GDP 6.48148
316 3RWO GDP 6.48649
317 4V0K GDP 6.50888
318 4U00 ADP 6.55738
319 3RC3 ANP 6.56455
320 3I7S PYR 6.56455
321 2W83 GTP 6.66667
322 4R2I ANP 6.66667
323 5JCZ GDP 6.70391
324 1Z0F GDP 6.70391
325 3FJG 3PG 6.77291
326 4LX0 BEF GDP 6.77966
327 4Q1A 2XZ 6.78337
328 4Q1A UDP 6.78337
329 2OAT PFM 6.83371
330 1B0U ATP 6.87023
331 4C4P GNP 6.93642
332 3N7S 3N7 6.95652
333 4OI4 ATP 6.95652
334 2OG2 MLI 6.96379
335 2HV8 GTP 6.97674
336 3UIE ANP 7
337 2KIN ADP 7
338 4X8O AP5 7.00935
339 4BAS GNP 7.03518
340 2HF9 GSP 7.07965
341 1TAD GDP 7.09877
342 1TAD ALF 7.09877
343 4TL6 ANP 7.11462
344 2D7C GTP 7.18563
345 2GDJ ANP 7.19697
346 1P9B GDP 7.22101
347 5I34 GDP 7.25624
348 2XT3 ADP 7.26744
349 1AKY AP5 7.27273
350 4ZI2 GNP 7.36842
351 4GOJ GNP 7.40741
352 1APZ ASP 7.40741
353 4D0G GTP 7.42857
354 4PJ3 ANP 7.43983
355 1SQ5 ADP 7.46753
356 2FH5 GTP 7.47664
357 1ZJ6 G3D 7.48663
358 3Q9L ATP 7.69231
359 1GXU 2HP 7.69231
360 5J1J ANP 7.7193
361 1D2N ANP 7.72059
362 1FZQ GDP 7.73481
363 2Y8E GNP 7.82123
364 3MJH GTP 7.87746
365 4ZKD GDP 7.87746
366 5K5Z ANP 7.96178
367 5GOE GDP 8.05687
368 3WYA GDP 8.06452
369 3CPJ GDP 8.07175
370 2GJ8 ALF GDP 8.13953
371 1PUJ GNP 8.15603
372 6G14 G4P 8.16327
373 1G16 GDP 8.23529
374 2RGX AP5 8.25243
375 1JJV ATP 8.25243
376 3B9Q MLI 8.27815
377 3ITJ CIT 8.28402
378 4XTR ATP 8.29493
379 4XVU ATP 8.29493
380 4XTR ADP 8.29493
381 1Z6T ADP 8.3151
382 1F9V ADP 8.35735
383 1YZG GDP 8.37989
384 4O48 ASP 8.43373
385 6CRK GDP 8.4507
386 1GP2 GDP 8.4507
387 5L3R GCP 8.53242
388 2IS6 ADP 8.53392
389 2QG6 NMN 8.54271
390 2QEN ADP 8.57143
391 3BC1 GNP 8.71795
392 4E03 ADP 8.73786
393 2QZ4 ADP 8.77863
394 4TTQ ATP 8.83721
395 4JLV ADP 8.92193
396 2WKQ GTP 9.03614
397 4BQS K2Q 9.09091
398 4BQS ADP 9.09091
399 3W5J GDP 9.31373
400 4LPS GDP 9.50413
401 1R4A GNP 9.69697
402 1W4R TTP 9.74359
403 1GWN GTP 9.7561
404 5KSP GDP 10
405 3IIJ ADP 10
406 3RLF ANP 10.1351
407 5GVR LMR 10.2564
408 1DAK ADP 10.2679
409 1DAK DPU 10.2679
410 2WZF BGC 10.2845
411 2ZTS ADP 10.3586
412 3A1S GDP 10.4651
413 3PCR GTP 10.4938
414 3N5C GDP 10.4938
415 1YTM ATP 10.5033
416 4RZ3 ADP 10.5085
417 3T12 GDP ALF 10.6061
418 3T1O GDP 10.6061
419 2ODE ALF GDP 10.6383
420 1QHH ATP 10.7784
421 2D2F ADP 10.8
422 1M7B GTP 10.8696
423 2A5F GTP 10.8808
424 1GOT GDP 10.9589
425 1XX6 ADP 10.9948
426 1WDT GTP 11.1597
427 1GS5 ANP 11.2403
428 1GS5 NLG 11.2403
429 1ZUI SKM 11.3095
430 2ZEJ GDP 11.413
431 1XMV ADP 11.5169
432 3A4M ADP 11.5385
433 4J0Q GDP 11.7783
434 1MKY GDP 11.8451
435 1KO8 6PG 12
436 5KDO GDP 12.1622
437 3CNL GNP 12.2137
438 3GJ0 GDP 12.6697
439 3ZIA ATP 12.6984
440 3ZIA ADP 12.6984
441 3M1I GTP 12.7854
442 3WYF GTP 12.7854
443 5BXQ GDP 12.963
444 1IBR GNP 12.963
445 3GJX GTP 12.963
446 3CH5 GDP 12.963
447 4HI0 GDP 13.0653
448 2QTV GNP 13.1737
449 3H4S ADP 13.3333
450 3U6B GDP 13.4518
451 5JBQ GDP 13.4518
452 4G5G GDP 13.4518
453 3U6K GDP 13.4518
454 4P3Y GDP 13.4518
455 4PC3 GDP 13.4518
456 2BVN GNP 13.486
457 1D8T GDP 13.486
458 4DCT GDP 13.5965
459 4CVN ADP 13.6126
460 4KAX GTP 13.6646
461 5OCG GNP 13.7566
462 5UQW GDP 13.7566
463 2VOH CIT 14.0127
464 5TB5 GDP 14.0541
465 5TAR GDP 14.0541
466 2O66 FLC 14.0741
467 2BCG GDP 14.0777
468 1F6B GDP 14.1414
469 1Z83 AP5 14.2857
470 3VPB GLU 14.2857
471 2C78 GNP 14.321
472 2C77 GNP 14.321
473 4M9Q GNP 14.5374
474 1JJ7 ADP 14.6154
475 1OS1 PYR 14.6608
476 1OS1 ATP 14.6608
477 1RYH GNP 14.7783
478 3IUY AMP 14.9123
479 3VX3 ADP 14.9194
480 2C5L GTP 15.0289
481 1NRJ GTP 15.1376
482 5LEF GTP 15.1515
483 4K81 GTP 15.2047
484 5W7Q GDP 15.2815
485 5OEC GDP 15.3005
486 5W76 GDP 15.3247
487 5O2T GSP 15.3846
488 3WYG GTP 15.3846
489 5E95 GDP 15.4762
490 2A9K GDP 15.508
491 5O74 GDP 15.5556
492 2J0V GDP 15.566
493 6D5E GNP 15.5689
494 6D55 GNP 15.5689
495 1LFD GNP 15.5689
496 6D5J GNP 15.5689
497 6D56 GNP 15.5689
498 6D5H GNP 15.5689
499 6D5G GNP 15.5689
500 6BVI GNP 15.5689
501 6BVL GNP 15.5689
502 6D5L GNP 15.5689
503 6BVK GNP 15.5689
504 6BVJ GNP 15.5689
505 6D59 GNP 15.5689
506 6BVM GNP 15.5689
507 6D5V GNP 15.5689
508 6D5M GNP 15.5689
509 6FA4 GNP 15.6069
510 3DDC GNP 15.6627
511 2UZI GTP 15.6627
512 1NVV GNP 15.6627
513 5WLB GNP 15.6627
514 1CLU DBG 15.6627
515 3KUD GDP 15.6627
516 1WQ1 GDP 15.6627
517 1WQ1 AF3 15.6627
518 3QBT GNP 15.7143
519 5W75 GDP 15.8163
520 1WA5 GTP 15.9091
521 5H7J GCP 15.9737
522 1GRN GDP 16.2304
523 1GRN AF3 16.2304
524 4ITR GDP 16.2304
525 2NGR GDP 16.2304
526 2NGR AF3 16.2304
527 5KUT GDP 16.4021
528 1RE0 GDP 16.4634
529 1S9D GDP 16.4634
530 1UAD GNP 16.5714
531 1ZC3 GNP 16.5714
532 5ZB0 ADP 16.6667
533 5ZB0 TYD 16.6667
534 2WMO GTP 16.8421
535 1UPT GTP 16.9591
536 1U8Z GDP 17.2619
537 5EE5 GTP 17.5439
538 3DOE GTP 17.5758
539 2YOH WMJ 17.619
540 1Z08 GNP 17.6471
541 4YC7 GNP 17.6796
542 4KVG GTP 17.8571
543 1Z2A GDP 17.8571
544 1M2O GNP 17.8947
545 1WF3 GNP 17.9402
546 1B7T ADP 17.9487
547 4HDO GNP 17.9641
548 1GUA GNP 17.9641
549 3X1Z GNP 17.9641
550 4HDQ GNP 17.9641
551 1KK8 BEF ADP 18.1818
552 5SZH GNP 18.2266
553 5H7K GDP 18.3879
554 5HCN GCP 18.3908
555 5WDR GNP 18.7134
556 5Y6N ADP 18.7215
557 3PQC GDP 18.9744
558 2WHX ADP 19.256
559 2JLR ANP 19.5122
560 1X1R GDP 19.6629
561 1J2J GTP 20
562 3KTA AP5 20.3297
563 1CS4 GSP 20.4444
564 3EC1 GDP 20.5962
565 2GCO GNP 20.8955
566 2GCN GDP 20.8955
567 1S8F GDP 20.904
568 3ZS9 ADP ALF 21.0526
569 1R2Q GNP 21.1765
570 2WIC GNP 21.3483
571 2GNK ATP 21.4286
572 1KAO GDP 21.5569
573 1CR1 TTP 21.6216
574 1E96 GTP 21.875
575 1I4D GDP 21.875
576 2EFE GNH 22.0994
577 5YV5 ADP 22.2222
578 4R98 GNH 22.5092
579 4D0N GDP 22.7027
580 1OW3 GDP 22.7979
581 1MH1 GNP 23.1183
582 1G4U GDP 23.3696
583 1G4U AF3 23.3696
584 2HT6 GDP 23.5632
585 6BCA GSP 23.7838
586 6BCB GSP 23.7838
587 6BC0 GSP 23.7838
588 3LXR GDP 23.7838
589 2A5J GDP 24.0838
590 2FJU GSP 24.1573
591 1HE1 GDP 24.4318
592 1HE1 AF3 24.4318
593 1CXZ GSP 24.7253
594 5IRC GDP 24.7312
595 5HPY GDP 24.8649
596 1KMQ GNP 25
597 3WY9 GDP 25
598 2OM2 GDP 25
599 1HTW ADP 25.3165
600 2EW1 GNP 25.3731
601 4XOI GTP 25.5556
602 5XC5 GTP 25.5682
603 4XSH GSP 25.6983
604 5DI3 GNP 25.9459
605 1TX4 ALF GDP 25.9887
606 3WXM GTP 26.3982
607 1Z0A GDP 26.4368
608 3T5G GDP 26.5193
609 3VMF GTP 26.8182
610 2BME GNP 26.8817
611 6BSX E7S 26.9663
612 6BSX GDP 26.9663
613 1NF3 GNP 27.1795
614 1A4R GDP 27.2251
615 1A4R GNH 27.2251
616 5UPK GNP 27.5676
617 3SBD GNP 27.8075
618 1TU3 GNP 27.8481
619 2W2X GSP 28.1081
620 4NON GDP 28.8462
621 1D5C GDP 29.0123
622 1DCP HBI 29.8077
623 1KY3 GDP 30.2198
624 1FQJ ALF 30.9524
625 1FQJ GDP 30.9524
626 4DID GDP 31.0881
627 1EK0 GNP 31.7647
628 1Z0K GTP 32.5581
629 2WJG GDP 32.9787
630 1VG8 GNP 33.8164
631 1VG0 GDP 33.8164
632 2WJH GDP 36.1446
633 2WJH FLC 36.1446
634 1Z0J GTP 36.4706
635 1YVD GNP 37.2781
636 1VG1 GDP 37.8378
637 1VG9 GDP 37.8378
638 5Z2M GTP 39.7727
Pocket No.: 2; Query (leader) PDB : 4NCN; Ligand: GTP; Similar sites found with APoc: 16
This union binding pocket(no: 2) in the query (biounit: 4ncn.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 6G1O GLV 1.96937
2 3ZH4 FLC 2.86396
3 5ZW3 SAH 3.11111
4 3R6K FUC GAL GLA 3.27869
5 4RLQ 3SK 3.28228
6 3LN9 FLC 3.59712
7 1WRA PC 4.22078
8 1BGV GLU 4.23163
9 1TE2 PGA 4.42478
10 4JLS 3ZE 4.60526
11 2ZX2 RAM 5.64103
12 1TLC DGP 6.03774
13 2NV2 GLN 7.43983
14 4UXH T5A 7.6087
15 2HIM ASN 8.37989
16 3MWL 8OX 8.69565
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