Receptor
PDB id Resolution Class Description Source Keywords
4N94 1.73 Å EC: 2.7.7.7 E. COLI SLIDING CLAMP IN COMPLEX WITH 3,4-DIFLUOROBENZAMIDE ESCHERICHIA COLI SLIDING CLAMP DNAN TRANSFERASE
Ref.: DISCOVERY OF LEAD COMPOUNDS TARGETING THE BACTERIAL CLAMP USING A FRAGMENT-BASED APPROACH. J.MED.CHEM. V. 57 2799 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PEG B:405;
 Invalid;
 none;
 submit data
106.12 C4 H10 O3 C(COC...
CL A:402;
 Invalid;
 none;
 submit data
35.453 Cl [Cl-]
CA B:403;
B:404;
 Part of Protein;
Invalid;
 none;
none;
 submit data
40.078 Ca [Ca+2...
2HO A:401;
 Valid;
 none;
 submit data
157.118 C7 H5 F2 N O c1cc(...
PG4 B:402;
B:401;
 Invalid;
Invalid;
 none;
none;
 submit data
194.226 C8 H18 O5 C(COC...
EDO B:406;
 Invalid;
 none;
 submit data
62.068 C2 H6 O2 C(CO)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4K3P 2.15 Å EC: 2.7.7.7 E. COLI SLIDING CLAMP IN COMPLEX WITH ACQLALF ESCHERICHIA COLI E. COLI SLIDING CLAMP TRANSFERASE
Ref.: STRUCTURAL AND THERMODYNAMIC DISSECTION OF LINEAR M RECOGNITION BY THE E. COLI SLIDING CLAMP J.MED.CHEM. V. 56 8665 2013
Members (22)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 21 families.
1 4MJR Ki = 283 uM 0LA C15 H12 Cl N O2 C[C@@H](c1....
2 4N94 - 2HO C7 H5 F2 N O c1cc(c(cc1....
3 4N98 Ki = 280 uM 4FC C13 H9 F O2 c1cc(ccc1c....
4 4N95 - 2HQ C8 H4 Cl N O2 c1cc2c(cc1....
5 4MJQ Ki = 193 uM 27R C15 H12 Br N O3 c1cc(c(c(c....
6 3D1E - THR LEU MET THR GLY GLN LEU GLY LEU PHE n/a n/a
7 6FVM - ACE GLN ALC ASP LEU PHE n/a n/a
8 3D1G Ki ~ 10 uM 322 C14 H13 Br2 N O5 S2 CCOc1cc(c(....
9 4K3O Kd = 36.7 uM ACE GLN ALA ASP LEU PHE n/a n/a
10 4K3L ic50 = 1.1 mM ACE LEU PHE n/a n/a
11 4N9A Ki = 64 uM 2J2 C13 H12 Cl N O2 c1cc2c(cc1....
12 4K3K ic50 = 4.44 mM SFK C15 H21 N O3 CC(C)CCC(=....
13 3D1F - SER GLU GLN VAL GLU LEU GLU PHE ASP 323 n/a n/a
14 4K3M Kd = 281.2 uM ALA LEU ASP LEU PHE n/a n/a
15 4K3R Kd = 259.1 uM ACE GLN LEU ASP LEU ALA n/a n/a
16 4K3Q Kd = 115.1 uM ACE GLN LEU ASP ALA PHE n/a n/a
17 4K3P Kd = 1.6 uM ACE GLN LEU ALA LEU PHE n/a n/a
18 4N99 Ki = 216 uM 2J1 C13 H12 Cl N O2 c1c2c(cc(c....
19 4MJP Ki = 131 uM 27O C19 H22 O2 C[C@H](c1c....
20 6FVL - ACE GLN ALC ASP LEU PHE n/a n/a
21 4N96 - 6NI C7 H5 N3 O2 c1cc2cn[nH....
22 4N97 - 2HU C8 H6 N2 O2 c1cc2c(cc[....
70% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 20 families.
1 4MJR Ki = 283 uM 0LA C15 H12 Cl N O2 C[C@@H](c1....
2 4N94 - 2HO C7 H5 F2 N O c1cc(c(cc1....
3 4N98 Ki = 280 uM 4FC C13 H9 F O2 c1cc(ccc1c....
4 4N95 - 2HQ C8 H4 Cl N O2 c1cc2c(cc1....
5 4MJQ Ki = 193 uM 27R C15 H12 Br N O3 c1cc(c(c(c....
6 3D1E - THR LEU MET THR GLY GLN LEU GLY LEU PHE n/a n/a
7 6FVM - ACE GLN ALC ASP LEU PHE n/a n/a
8 3D1G Ki ~ 10 uM 322 C14 H13 Br2 N O5 S2 CCOc1cc(c(....
9 4K3O Kd = 36.7 uM ACE GLN ALA ASP LEU PHE n/a n/a
10 4K3L ic50 = 1.1 mM ACE LEU PHE n/a n/a
11 4N9A Ki = 64 uM 2J2 C13 H12 Cl N O2 c1cc2c(cc1....
12 4K3K ic50 = 4.44 mM SFK C15 H21 N O3 CC(C)CCC(=....
13 3D1F - SER GLU GLN VAL GLU LEU GLU PHE ASP 323 n/a n/a
14 4K3M Kd = 281.2 uM ALA LEU ASP LEU PHE n/a n/a
15 4K3R Kd = 259.1 uM ACE GLN LEU ASP LEU ALA n/a n/a
16 4K3Q Kd = 115.1 uM ACE GLN LEU ASP ALA PHE n/a n/a
17 4K3P Kd = 1.6 uM ACE GLN LEU ALA LEU PHE n/a n/a
18 4N99 Ki = 216 uM 2J1 C13 H12 Cl N O2 c1c2c(cc(c....
19 4MJP Ki = 131 uM 27O C19 H22 O2 C[C@H](c1c....
20 6FVL - ACE GLN ALC ASP LEU PHE n/a n/a
21 4N96 - 6NI C7 H5 N3 O2 c1cc2cn[nH....
22 4N97 - 2HU C8 H6 N2 O2 c1cc2c(cc[....
23 4TSZ Kd = 99 nM ACE GLN ALC ASP LEU ZCL n/a n/a
50% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 20 families.
1 4MJR Ki = 283 uM 0LA C15 H12 Cl N O2 C[C@@H](c1....
2 4N94 - 2HO C7 H5 F2 N O c1cc(c(cc1....
3 4N98 Ki = 280 uM 4FC C13 H9 F O2 c1cc(ccc1c....
4 4N95 - 2HQ C8 H4 Cl N O2 c1cc2c(cc1....
5 4MJQ Ki = 193 uM 27R C15 H12 Br N O3 c1cc(c(c(c....
6 3D1E - THR LEU MET THR GLY GLN LEU GLY LEU PHE n/a n/a
7 6FVM - ACE GLN ALC ASP LEU PHE n/a n/a
8 3D1G Ki ~ 10 uM 322 C14 H13 Br2 N O5 S2 CCOc1cc(c(....
9 4K3O Kd = 36.7 uM ACE GLN ALA ASP LEU PHE n/a n/a
10 4K3L ic50 = 1.1 mM ACE LEU PHE n/a n/a
11 4N9A Ki = 64 uM 2J2 C13 H12 Cl N O2 c1cc2c(cc1....
12 4K3K ic50 = 4.44 mM SFK C15 H21 N O3 CC(C)CCC(=....
13 3D1F - SER GLU GLN VAL GLU LEU GLU PHE ASP 323 n/a n/a
14 4K3M Kd = 281.2 uM ALA LEU ASP LEU PHE n/a n/a
15 4K3R Kd = 259.1 uM ACE GLN LEU ASP LEU ALA n/a n/a
16 4K3Q Kd = 115.1 uM ACE GLN LEU ASP ALA PHE n/a n/a
17 4K3P Kd = 1.6 uM ACE GLN LEU ALA LEU PHE n/a n/a
18 4N99 Ki = 216 uM 2J1 C13 H12 Cl N O2 c1c2c(cc(c....
19 4MJP Ki = 131 uM 27O C19 H22 O2 C[C@H](c1c....
20 6FVL - ACE GLN ALC ASP LEU PHE n/a n/a
21 4N96 - 6NI C7 H5 N3 O2 c1cc2cn[nH....
22 4N97 - 2HU C8 H6 N2 O2 c1cc2c(cc[....
23 4TSZ Kd = 99 nM ACE GLN ALC ASP LEU ZCL n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 2HO; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 2HO 1 1
2 9TW 0.529412 0.954545
3 93K 0.4 0.62963
Similar Ligands (3D)
Ligand no: 1; Ligand: 2HO; Similar ligands found: 1364
No: Ligand Similarity coefficient
1 DHB 1.0000
2 MYJ 1.0000
3 4NC 1.0000
4 JLZ 1.0000
5 P9P 1.0000
6 FHB 1.0000
7 4A3 1.0000
8 3HM 1.0000
9 NNO 1.0000
10 INO 1.0000
11 CHB 1.0000
12 XX2 0.9952
13 QSB 0.9932
14 IHB 0.9885
15 HBD 0.9790
16 3HB 0.9785
17 PHB 0.9776
18 4CS 0.9770
19 F31 0.9756
20 PAB 0.9745
21 NPO 0.9738
22 ZXD 0.9736
23 8WO 0.9734
24 GDE 0.9731
25 GAB 0.9725
26 4MA 0.9717
27 WCE 0.9714
28 1Y6 0.9692
29 VNL 0.9691
30 SKM 0.9690
31 PBZ 0.9682
32 P72 0.9680
33 4AA 0.9679
34 826 0.9678
35 3AB 0.9677
36 DHK 0.9677
37 3NT 0.9676
38 LNR 0.9673
39 AC6 0.9671
40 OVV 0.9661
41 0HO 0.9655
42 KOJ 0.9652
43 4FH 0.9646
44 53C 0.9646
45 8GC 0.9644
46 0HN 0.9644
47 NMJ 0.9636
48 4XR 0.9636
49 X0V 0.9633
50 1F1 0.9628
51 4SX 0.9628
52 174 0.9627
53 4ZA 0.9625
54 IFP 0.9620
55 BRT 0.9619
56 3PF 0.9616
57 Z82 0.9610
58 BGC 0.9605
59 5WV 0.9603
60 EKZ 0.9597
61 SW7 0.9595
62 GYE 0.9594
63 4P5 0.9590
64 5QY 0.9590
65 5HN 0.9588
66 ISN 0.9587
67 6NT 0.9582
68 6NI 0.9578
69 3NY 0.9576
70 4WL 0.9572
71 LDP 0.9572
72 KKN 0.9568
73 HX3 0.9564
74 3BZ 0.9556
75 QSH 0.9556
76 BEZ 0.9552
77 ES7 0.9549
78 2HU 0.9544
79 FA0 0.9542
80 LCN 0.9540
81 2ZM 0.9539
82 GZL 0.9535
83 2A9 0.9529
84 TWO 0.9525
85 G3E 0.9525
86 3A9 0.9523
87 E7Z 0.9523
88 3ID 0.9523
89 3OC 0.9522
90 4Z4 0.9521
91 ASC 0.9519
92 FGZ 0.9519
93 L99 0.9516
94 5OB 0.9515
95 GLC 0.9512
96 D48 0.9512
97 5NI 0.9511
98 CN0 0.9510
99 BDP 0.9505
100 4M0 0.9504
101 12Q 0.9504
102 PZI 0.9502
103 LT2 0.9501
104 DMD 0.9499
105 H42 0.9497
106 ABI 0.9495
107 3HA 0.9493
108 J5I 0.9493
109 3DO 0.9491
110 JAW 0.9489
111 7W4 0.9488
112 VXX 0.9487
113 86J 0.9487
114 BZ2 0.9480
115 HIS 0.9480
116 7W1 0.9480
117 NCA 0.9480
118 97T 0.9476
119 TTL 0.9475
120 ASO 0.9470
121 G4D 0.9470
122 DBH 0.9470
123 J9Q 0.9468
124 DOB 0.9467
125 CFI 0.9466
126 ESP 0.9465
127 5CU 0.9464
128 2AL 0.9461
129 BHA 0.9460
130 15N 0.9457
131 BEN 0.9457
132 GTQ 0.9456
133 ANN 0.9454
134 V55 0.9453
135 2HQ 0.9453
136 PBC 0.9451
137 G3F 0.9450
138 3F0 0.9450
139 AZ9 0.9450
140 5RO 0.9449
141 SVD 0.9448
142 HHA 0.9446
143 G2F 0.9446
144 SE2 0.9446
145 6PC 0.9445
146 SAL 0.9445
147 SYV 0.9443
148 4XV 0.9442
149 ICO 0.9440
150 M2K 0.9439
151 SKA 0.9439
152 AC0 0.9439
153 BZ3 0.9438
154 HBA 0.9438
155 5RN 0.9434
156 BE2 0.9434
157 PAC 0.9433
158 JDN 0.9433
159 67N 0.9431
160 BAM 0.9430
161 HQT 0.9429
162 HA5 0.9428
163 5RG 0.9425
164 DGJ 0.9422
165 AHR 0.9422
166 5XC 0.9421
167 5M0 0.9421
168 3MB 0.9421
169 M1A 0.9419
170 6CS 0.9416
171 IF7 0.9415
172 KUF 0.9414
173 E5X 0.9413
174 PNZ 0.9412
175 PHU 0.9410
176 CWS 0.9410
177 Q88 0.9408
178 069 0.9408
179 HQJ 0.9407
180 UNU 0.9406
181 8S0 0.9405
182 NOY 0.9405
183 AL0 0.9404
184 1P3 0.9403
185 OAA 0.9403
186 COU 0.9401
187 4HM 0.9400
188 NIO 0.9400
189 ORO 0.9400
190 1LQ 0.9399
191 IFL 0.9398
192 0P6 0.9398
193 NOJ 0.9396
194 PIM 0.9394
195 AX7 0.9394
196 XIY 0.9394
197 GLU 0.9392
198 GAL 0.9392
199 RSO 0.9392
200 RAT 0.9390
201 GTR 0.9388
202 7WR 0.9388
203 A7W 0.9388
204 YCP 0.9388
205 6FZ 0.9386
206 5QX 0.9386
207 FAN 0.9385
208 54G 0.9385
209 4FS 0.9384
210 ISZ 0.9383
211 CWM 0.9383
212 D1X 0.9382
213 4M4 0.9381
214 45L 0.9380
215 F0J 0.9379
216 4SV 0.9379
217 NBZ 0.9379
218 EUG 0.9378
219 ABV 0.9378
220 1SQ 0.9378
221 4XS 0.9377
222 JBK 0.9377
223 MLT 0.9377
224 4BZ 0.9375
225 9TZ 0.9374
226 52C 0.9373
227 NTN 0.9373
228 8WT 0.9372
229 03V 0.9372
230 3M0 0.9371
231 0JD 0.9371
232 0N7 0.9369
233 TYL 0.9369
234 5NU 0.9369
235 HDH 0.9366
236 DIN 0.9366
237 2AQ 0.9365
238 TPA 0.9361
239 ICB 0.9360
240 HQD 0.9360
241 BEA 0.9358
242 LYL 0.9357
243 XM0 0.9357
244 SS1 0.9357
245 1NP 0.9357
246 XX3 0.9354
247 DHS 0.9354
248 2BG 0.9354
249 173 0.9353
250 OCH 0.9352
251 SHA 0.9351
252 3IT 0.9351
253 OVM 0.9348
254 L5V 0.9348
255 270 0.9348
256 1P7 0.9348
257 ESX 0.9348
258 OXC 0.9347
259 FBW 0.9347
260 PZA 0.9347
261 EA1 0.9346
262 ES6 0.9346
263 ESI 0.9344
264 SAN 0.9342
265 4FA 0.9341
266 6RQ 0.9340
267 DNF 0.9340
268 TSU 0.9340
269 24W 0.9338
270 ADA 0.9337
271 BHO 0.9336
272 N5J 0.9336
273 XXG 0.9334
274 SOE 0.9334
275 TH7 0.9333
276 ES0 0.9332
277 FE DB1 0.9331
278 JB5 0.9330
279 0F9 0.9330
280 EOL 0.9329
281 5MK 0.9329
282 ES5 0.9329
283 MRW 0.9329
284 6TZ 0.9328
285 NIZ 0.9328
286 DYA 0.9327
287 9FL 0.9324
288 UFV 0.9322
289 ES2 0.9321
290 4VP 0.9320
291 FP1 0.9320
292 FOT 0.9319
293 BCU 0.9318
294 IV2 0.9318
295 GCS 0.9317
296 PXL 0.9317
297 KTA 0.9316
298 MR1 0.9316
299 GJZ 0.9315
300 0W8 0.9314
301 MQN 0.9312
302 4JQ 0.9311
303 VGL 0.9309
304 15L 0.9308
305 4NM 0.9308
306 ET2 0.9308
307 7MU 0.9306
308 717 0.9306
309 4J8 0.9306
310 CTL 0.9306
311 GVG 0.9305
312 ONR 0.9304
313 FBM 0.9302
314 SRT 0.9300
315 4JT 0.9300
316 AMH 0.9299
317 Q6T 0.9298
318 FBS 0.9297
319 1P8 0.9296
320 8CM 0.9293
321 JPZ 0.9293
322 JAE 0.9291
323 C2Y 0.9291
324 PRZ 0.9290
325 ES1 0.9290
326 14O 0.9290
327 M4T 0.9289
328 HMH 0.9289
329 5IQ 0.9289
330 E1T 0.9288
331 JBE 0.9288
332 DHR 0.9287
333 OXZ 0.9286
334 BPN 0.9286
335 FA1 0.9285
336 8ZE 0.9284
337 6M9 0.9283
338 FBB 0.9282
339 F60 0.9281
340 4YS 0.9280
341 COI 0.9279
342 PIY 0.9279
343 2LP 0.9278
344 QSC 0.9277
345 OW4 0.9277
346 2MI 0.9277
347 DOR 0.9277
348 K2T 0.9277
349 BZX 0.9277
350 I3A 0.9277
351 9CA 0.9276
352 K97 0.9276
353 P92 0.9275
354 51R 0.9274
355 MSR 0.9274
356 261 0.9273
357 QUZ 0.9273
358 1M2 0.9271
359 A29 0.9271
360 82I 0.9271
361 JKE 0.9270
362 FCR 0.9269
363 QIC 0.9269
364 R8V 0.9269
365 XQ0 0.9269
366 CLW 0.9268
367 VGD 0.9268
368 NPY 0.9268
369 UNC 0.9268
370 H7Y 0.9266
371 3U4 0.9266
372 ODO 0.9266
373 GUA 0.9266
374 AAS 0.9265
375 R20 0.9265
376 0TU 0.9265
377 IFM 0.9264
378 VOH 0.9264
379 M3H 0.9264
380 BSX 0.9263
381 SN4 0.9262
382 3XX 0.9262
383 6AI 0.9261
384 9FE 0.9260
385 GCU 0.9259
386 SLS 0.9259
387 2D0 0.9259
388 RIB 0.9258
389 GLA 0.9257
390 RNS 0.9256
391 AEF 0.9256
392 F9P 0.9256
393 JBH 0.9255
394 QWN 0.9255
395 5H1 0.9254
396 HIO 0.9253
397 5Q0 0.9253
398 LMR 0.9252
399 5SG 0.9251
400 4YO 0.9251
401 LGC 0.9250
402 92K 0.9250
403 42C 0.9250
404 XCZ 0.9248
405 MCT 0.9248
406 OTR 0.9245
407 36R 0.9245
408 K34 0.9243
409 92P 0.9242
410 BNS 0.9241
411 42J 0.9240
412 JFJ 0.9240
413 YRL 0.9240
414 H8N 0.9239
415 BE7 0.9238
416 2CK 0.9236
417 1PT 0.9236
418 268 0.9234
419 AW5 0.9234
420 PEA 0.9234
421 HQY 0.9233
422 2K4 0.9231
423 5B1 0.9231
424 RM1 0.9231
425 M45 0.9230
426 GLN 0.9229
427 12T 0.9229
428 1IT 0.9229
429 15E 0.9229
430 TGX 0.9228
431 I1E 0.9224
432 3Z8 0.9224
433 KJU 0.9224
434 MS9 0.9223
435 11S 0.9223
436 34D 0.9221
437 2FY 0.9219
438 X6X 0.9219
439 AMS 0.9219
440 9ZE 0.9218
441 2FG 0.9217
442 GXL 0.9216
443 F05 0.9216
444 AKH 0.9214
445 5MB 0.9214
446 149 0.9214
447 CXF 0.9213
448 7NI 0.9213
449 4XH 0.9213
450 WOO 0.9211
451 IT2 0.9211
452 4HO 0.9210
453 MZG 0.9210
454 NDH 0.9206
455 5VM 0.9206
456 CH9 0.9204
457 HC4 0.9203
458 GAF 0.9202
459 2H5 0.9200
460 4ME 0.9200
461 CPZ 0.9199
462 K5W 0.9199
463 ASP 0.9198
464 QXW 0.9198
465 7B4 0.9198
466 5LA 0.9196
467 URC 0.9196
468 2HC 0.9196
469 9EW 0.9195
470 N8Y 0.9193
471 MAJ 0.9191
472 NCT 0.9190
473 DE5 0.9190
474 F4E 0.9190
475 TIU 0.9190
476 H4E 0.9189
477 SX1 0.9189
478 HJP 0.9189
479 FYU 0.9188
480 36Y 0.9188
481 XYL 0.9186
482 ALL 0.9186
483 RB5 0.9186
484 KTW 0.9185
485 B85 0.9185
486 HY1 0.9184
487 0RW 0.9182
488 JA8 0.9181
489 7N0 0.9180
490 5MI 0.9180
491 OGA 0.9180
492 S2G 0.9179
493 JG8 0.9179
494 1MC 0.9178
495 FK1 0.9178
496 0W1 0.9177
497 BR9 0.9177
498 GIV 0.9176
499 SVN 0.9176
500 URF 0.9175
501 27Y 0.9174
502 4JM 0.9174
503 ZYR 0.9174
504 PQK 0.9173
505 7HQ 0.9173
506 TZF 0.9173
507 6M4 0.9173
508 KT7 0.9173
509 8XL 0.9172
510 MWJ 0.9172
511 39O 0.9172
512 MBG 0.9172
513 ADE 0.9172
514 4JJ 0.9170
515 23A 0.9168
516 F9Y 0.9166
517 7WV 0.9164
518 4CL 0.9163
519 ES9 0.9163
520 DGN 0.9162
521 IJZ 0.9162
522 KBB 0.9162
523 OVP 0.9160
524 4AV 0.9159
525 M6N 0.9159
526 Z5P 0.9158
527 AMC 0.9158
528 2LY 0.9157
529 AKG 0.9157
530 XBZ 0.9155
531 4ZE 0.9153
532 4NG 0.9152
533 HH8 0.9152
534 TTY 0.9152
535 XYD 0.9151
536 SNU 0.9151
537 AEH 0.9150
538 259 0.9150
539 A1U 0.9150
540 4JL 0.9149
541 36E 0.9149
542 5JC 0.9148
543 XHP 0.9146
544 GCB 0.9145
545 QY9 0.9143
546 SJ5 0.9142
547 GF4 0.9142
548 MWM 0.9141
549 N2I 0.9140
550 TH0 0.9138
551 FH2 0.9138
552 B62 0.9138
553 XYP 0.9138
554 AZ8 0.9138
555 1GN 0.9137
556 ORN 0.9136
557 IPB 0.9135
558 5GU 0.9135
559 3FH 0.9135
560 2YU 0.9135
561 2AC 0.9134
562 H4N 0.9134
563 ADZ 0.9133
564 JZ2 0.9132
565 EXD 0.9131
566 6ME 0.9131
567 2FQ 0.9131
568 LZM 0.9130
569 2MP 0.9130
570 8H8 0.9130
571 TDR 0.9129
572 4P0 0.9128
573 AJ2 0.9128
574 FB1 0.9127
575 DHI 0.9126
576 EYK 0.9126
577 PO6 0.9125
578 EVA 0.9125
579 34A 0.9125
580 FA3 0.9124
581 MWP 0.9122
582 5XB 0.9121
583 RNT 0.9119
584 FDK 0.9118
585 G6D 0.9118
586 FQI 0.9117
587 LXC 0.9117
588 75K 0.9116
589 MPV 0.9116
590 FBV 0.9116
591 UNJ 0.9116
592 HPA 0.9116
593 PA1 0.9115
594 FDR 0.9115
595 NSP 0.9115
596 M58 0.9114
597 X05 0.9113
598 275 0.9113
599 PYF 0.9113
600 XAZ 0.9112
601 MNN 0.9111
602 HMU 0.9111
603 RHU 0.9111
604 OTW 0.9110
605 OK7 0.9109
606 1DJ 0.9109
607 1DW 0.9108
608 FDB 0.9108
609 A13 0.9106
610 5MH 0.9106
611 ZZT 0.9105
612 C2U 0.9105
613 GRE 0.9105
614 MUA 0.9105
615 9R5 0.9104
616 S2P 0.9103
617 C1M 0.9103
618 FPI 0.9103
619 J9T 0.9102
620 1WD 0.9102
621 DEW 0.9100
622 F12 0.9100
623 1A7 0.9099
624 DQU 0.9099
625 QX2 0.9099
626 ALE 0.9098
627 XDE 0.9098
628 WBU 0.9097
629 42A 0.9097
630 0FO 0.9097
631 PD2 0.9096
632 SWA 0.9095
633 AJY 0.9095
634 SOR 0.9094
635 ICP 0.9094
636 PYD 0.9094
637 PBA 0.9094
638 TOF 0.9093
639 QMP 0.9092
640 FB2 0.9092
641 2O6 0.9091
642 4MU 0.9091
643 AX3 0.9090
644 0BP 0.9090
645 GIF 0.9089
646 KBG 0.9087
647 4HC 0.9087
648 7VS 0.9087
649 428 0.9087
650 GLT 0.9085
651 M0Q 0.9085
652 MEW 0.9084
653 HT4 0.9083
654 6M1 0.9083
655 DEN 0.9083
656 KJY 0.9082
657 B57 0.9082
658 P3K 0.9081
659 URQ 0.9081
660 M5K 0.9081
661 VNJ 0.9080
662 YIO 0.9078
663 2EC 0.9076
664 PDC 0.9076
665 DMJ 0.9075
666 CTS 0.9075
667 HBX 0.9075
668 2CQ 0.9075
669 2HG 0.9073
670 Q24 0.9072
671 HLZ 0.9072
672 IAC 0.9072
673 43M 0.9071
674 4BY 0.9071
675 DHY 0.9069
676 FBA 0.9068
677 7WG 0.9068
678 DBX 0.9068
679 I3E 0.9067
680 44W 0.9067
681 HPS 0.9066
682 SHG 0.9065
683 AQO 0.9065
684 3DM 0.9065
685 10L 0.9065
686 APZ 0.9064
687 3PG 0.9063
688 ALA ALA 0.9063
689 PMB 0.9062
690 HLR 0.9062
691 37T 0.9062
692 HSO 0.9061
693 5WY 0.9060
694 GUN 0.9059
695 8TX 0.9059
696 0FK 0.9057
697 N2Z 0.9057
698 BTY 0.9057
699 C2B 0.9057
700 258 0.9056
701 YPN 0.9056
702 AZA 0.9056
703 GGL 0.9055
704 HHH 0.9055
705 IWT 0.9055
706 6LW 0.9054
707 8HC 0.9054
708 TM7 0.9054
709 DGL 0.9053
710 24B 0.9053
711 2F6 0.9053
712 3Z7 0.9053
713 AJV 0.9052
714 PEY 0.9052
715 0R0 0.9052
716 XUL 0.9051
717 S76 0.9051
718 AY4 0.9051
719 8NY 0.9051
720 3SK 0.9051
721 6MP 0.9051
722 9MG 0.9051
723 6KT 0.9050
724 H62 0.9050
725 3AL 0.9050
726 GXY 0.9048
727 KJH 0.9046
728 L14 0.9043
729 R8S 0.9043
730 IND 0.9043
731 NLE 0.9042
732 TAG 0.9042
733 URO 0.9042
734 JZ3 0.9041
735 8OZ 0.9040
736 HDL 0.9038
737 DIU 0.9037
738 TZE 0.9036
739 ASN 0.9035
740 XAN 0.9035
741 JTH 0.9034
742 Y8I 0.9033
743 150 0.9033
744 BPY 0.9032
745 C2A 0.9029
746 AGK 0.9029
747 25W 0.9028
748 M4E 0.9027
749 0FN 0.9027
750 MXN 0.9026
751 XBT 0.9026
752 94W 0.9025
753 PEP 0.9025
754 44V 0.9025
755 ABN 0.9025
756 QPR 0.9025
757 DHQ 0.9022
758 TSS 0.9022
759 9DA 0.9022
760 SS2 0.9021
761 3MG 0.9021
762 NK 0.9021
763 OMD 0.9021
764 SEP 0.9020
765 5UC 0.9020
766 AH8 0.9019
767 FUD 0.9019
768 SD4 0.9018
769 9DG 0.9018
770 TAR 0.9017
771 EMZ 0.9017
772 2GS 0.9017
773 B55 0.9017
774 J6W 0.9016
775 PJW 0.9016
776 2AK 0.9015
777 TCA 0.9015
778 R67 0.9014
779 M4S 0.9014
780 BZI 0.9014
781 2FT 0.9013
782 UAN 0.9012
783 5JQ 0.9012
784 14J 0.9012
785 LZ1 0.9012
786 9HX 0.9011
787 DS0 0.9010
788 3ZB 0.9010
789 TLD 0.9009
790 6F0 0.9009
791 HHI 0.9009
792 DQA 0.9008
793 4V2 0.9008
794 MJ2 0.9006
795 OHP 0.9006
796 SYN 0.9005
797 4RU 0.9004
798 32X 0.9004
799 PZM 0.9003
800 NYL 0.9003
801 MNM 0.9003
802 BDF 0.9002
803 3BU 0.9002
804 XXP 0.9002
805 4NB 0.9001
806 PY7 0.9001
807 BZF 0.9000
808 RXA 0.8998
809 TSR 0.8997
810 MVN 0.8997
811 1SA 0.8997
812 7HP 0.8996
813 1LN 0.8995
814 XQG 0.8995
815 FBU 0.8995
816 4ZC 0.8995
817 AN3 0.8994
818 7WA 0.8994
819 4JP 0.8994
820 8NX 0.8993
821 SMN 0.8992
822 TT4 0.8992
823 INE 0.8992
824 E7S 0.8992
825 RMN 0.8990
826 EDR 0.8990
827 DNC 0.8990
828 PHE 0.8990
829 GLO 0.8989
830 N3W 0.8989
831 PE0 0.8989
832 6AP 0.8988
833 SYA 0.8988
834 RBL 0.8987
835 BP1 0.8987
836 8NB 0.8986
837 AZF 0.8985
838 GJP 0.8985
839 VK3 0.8985
840 CXP 0.8983
841 DRL 0.8983
842 IGA 0.8983
843 KDV 0.8982
844 3SL 0.8981
845 1XN 0.8981
846 PCA 0.8980
847 KYA 0.8980
848 G5V 0.8980
849 IDM 0.8980
850 3R6 0.8978
851 BNL 0.8977
852 URS 0.8977
853 KTJ 0.8977
854 GV9 0.8976
855 A5E 0.8976
856 MT0 0.8976
857 3QM 0.8975
858 2PG 0.8974
859 9KT 0.8974
860 4JC 0.8973
861 FK8 0.8971
862 SR1 0.8971
863 1KP 0.8968
864 A2F 0.8967
865 P7Y 0.8965
866 4BL 0.8965
867 CFF 0.8965
868 F4Z 0.8964
869 ZB1 0.8963
870 TEO 0.8961
871 R9Y 0.8961
872 4JO 0.8961
873 JYB 0.8961
874 GZ3 0.8960
875 CWJ 0.8960
876 54D 0.8960
877 DEE 0.8959
878 3HP 0.8958
879 1AL 0.8958
880 4TU 0.8958
881 NAG 0.8958
882 CFP 0.8957
883 1HN 0.8956
884 6GU 0.8955
885 2A7 0.8955
886 J9N 0.8955
887 FPY 0.8954
888 BTE 0.8954
889 BNF 0.8953
890 3C4 0.8952
891 1WG 0.8952
892 GAG 0.8952
893 0CT 0.8952
894 PEQ 0.8951
895 0V5 0.8951
896 RIP 0.8951
897 LQ2 0.8951
898 M6W 0.8950
899 NQ 0.8950
900 MPI 0.8950
901 RUY 0.8948
902 OKG 0.8948
903 EV0 0.8947
904 XDK 0.8947
905 AEG 0.8947
906 BP9 0.8947
907 HX4 0.8946
908 495 0.8946
909 PRY 0.8945
910 PKU 0.8944
911 0LH 0.8944
912 MZB 0.8944
913 TC7 0.8944
914 NGO 0.8943
915 8U3 0.8943
916 T6C 0.8943
917 B53 0.8942
918 GWM 0.8940
919 141 0.8940
920 ES4 0.8940
921 XRG 0.8939
922 CXH 0.8938
923 GVH 0.8938
924 DX4 0.8937
925 2ZV 0.8937
926 EGR 0.8936
927 ICF 0.8935
928 45C 0.8935
929 SME 0.8934
930 PEL 0.8934
931 IUR 0.8934
932 7MX 0.8933
933 PYQ 0.8933
934 DBJ 0.8931
935 282 0.8931
936 ZBT 0.8931
937 290 0.8930
938 MAN 0.8928
939 TEP 0.8928
940 505 0.8926
941 8G0 0.8926
942 JB8 0.8923
943 0R1 0.8923
944 Z6J 0.8922
945 M1E 0.8922
946 DIE 0.8921
947 NID 0.8920
948 PRF 0.8919
949 APG 0.8919
950 1MR 0.8918
951 C21 0.8918
952 JZ4 0.8917
953 EN1 0.8916
954 6R8 0.8914
955 PM6 0.8914
956 YH7 0.8913
957 8IG 0.8913
958 EVF 0.8912
959 209 0.8912
960 HSE 0.8911
961 AZG 0.8911
962 GO2 0.8911
963 OXQ 0.8911
964 GOX 0.8910
965 F81 0.8910
966 LDU 0.8910
967 R2B 0.8909
968 AHN 0.8909
969 FRU 0.8909
970 E4P 0.8908
971 JIF 0.8908
972 AS3 0.8906
973 OW7 0.8906
974 7MH 0.8906
975 23J 0.8906
976 QBM 0.8905
977 3HG 0.8905
978 DFB 0.8902
979 HH5 0.8901
980 DFU 0.8900
981 RAM 0.8897
982 5JL 0.8896
983 GCO 0.8896
984 PRA 0.8894
985 A09 0.8894
986 PH2 0.8894
987 LYS 0.8893
988 LKA 0.8893
989 JZ9 0.8892
990 R8A 0.8892
991 30G 0.8890
992 69O 0.8890
993 KBZ 0.8889
994 PXM 0.8887
995 PFB 0.8885
996 TZC 0.8884
997 TYE 0.8883
998 M5H 0.8883
999 8W9 0.8883
1000 FUL 0.8883
1001 X0W 0.8882
1002 APS 0.8881
1003 XYS 0.8881
1004 C9E 0.8880
1005 DA4 0.8880
1006 1XM 0.8880
1007 0MK 0.8879
1008 9X7 0.8878
1009 61M 0.8877
1010 BOA 0.8876
1011 60P 0.8875
1012 7MK 0.8873
1013 3QV 0.8872
1014 LRH 0.8871
1015 RBJ 0.8871
1016 JZ5 0.8871
1017 PQ0 0.8871
1018 NBE 0.8870
1019 Q02 0.8870
1020 2MN 0.8869
1021 PPY 0.8868
1022 2DR 0.8868
1023 HZQ 0.8868
1024 9RW 0.8867
1025 BK9 0.8867
1026 MO8 0.8867
1027 7VP 0.8867
1028 MET 0.8867
1029 R2P 0.8866
1030 LI6 0.8865
1031 4HP 0.8864
1032 L22 0.8864
1033 RD4 0.8864
1034 2BX 0.8862
1035 ZZ3 0.8862
1036 7ZE 0.8861
1037 6OT 0.8860
1038 R9S 0.8860
1039 2MH 0.8860
1040 95Z 0.8859
1041 PHH 0.8859
1042 6VD 0.8856
1043 SNO 0.8856
1044 3WA 0.8856
1045 XIZ 0.8854
1046 5VL 0.8854
1047 A65 0.8853
1048 GBD 0.8852
1049 YZM 0.8851
1050 1LM 0.8851
1051 HQ9 0.8849
1052 TLA 0.8848
1053 O72 0.8847
1054 IDH 0.8844
1055 RSF 0.8844
1056 PRO 0.8843
1057 M0W 0.8843
1058 SF9 0.8841
1059 JF2 0.8839
1060 TP5 0.8839
1061 N7I 0.8839
1062 4VY 0.8838
1063 K3Q 0.8837
1064 286 0.8837
1065 1Z6 0.8837
1066 27B 0.8837
1067 JXN 0.8834
1068 H76 0.8834
1069 BML 0.8832
1070 ABE 0.8831
1071 HHR 0.8831
1072 SKF 0.8831
1073 9PY 0.8830
1074 1DV 0.8829
1075 UFO 0.8828
1076 HY3 0.8827
1077 HSM 0.8826
1078 EQT 0.8826
1079 293 0.8825
1080 NVU 0.8824
1081 KMH 0.8824
1082 B2J 0.8822
1083 RNO 0.8821
1084 GBN 0.8821
1085 GZ2 0.8821
1086 13P 0.8821
1087 SMV 0.8821
1088 B60 0.8820
1089 BCP 0.8820
1090 FOA 0.8820
1091 3RK 0.8819
1092 SRO 0.8819
1093 JBN 0.8819
1094 449 0.8817
1095 7VJ 0.8817
1096 JFD 0.8817
1097 6QF 0.8816
1098 GOJ 0.8815
1099 1DU 0.8815
1100 329 0.8815
1101 FBT 0.8815
1102 GIO 0.8814
1103 HCI 0.8812
1104 7D2 0.8812
1105 PH3 0.8812
1106 JF1 0.8810
1107 B40 0.8809
1108 AA 0.8809
1109 1QP 0.8807
1110 KGK 0.8807
1111 KYD 0.8807
1112 FUF 0.8806
1113 ARP 0.8805
1114 LAO 0.8805
1115 LEU 0.8805
1116 ZWZ 0.8804
1117 QWW 0.8804
1118 F1A 0.8803
1119 4JU 0.8802
1120 SXS 0.8799
1121 JBQ 0.8798
1122 OHG 0.8797
1123 CLZ 0.8796
1124 ROI 0.8796
1125 F4K 0.8796
1126 FBJ 0.8795
1127 PMF 0.8794
1128 H33 0.8794
1129 IOS 0.8793
1130 BZE 0.8793
1131 UEG 0.8792
1132 FUC 0.8792
1133 JF6 0.8790
1134 AHB 0.8789
1135 FHC 0.8789
1136 344 0.8789
1137 TBP 0.8787
1138 1XA 0.8787
1139 9YL 0.8783
1140 MRZ 0.8782
1141 O2A 0.8780
1142 LSA 0.8780
1143 0CU 0.8778
1144 47J 0.8778
1145 SC2 0.8776
1146 YTX 0.8775
1147 1WC 0.8775
1148 2K8 0.8775
1149 X0U 0.8773
1150 FUM 0.8773
1151 DX3 0.8773
1152 PYJ 0.8772
1153 RJY 0.8772
1154 8XQ 0.8771
1155 II6 0.8770
1156 KMT 0.8770
1157 XXR 0.8769
1158 BMA 0.8768
1159 FF2 0.8768
1160 0XT 0.8768
1161 GHM 0.8767
1162 535 0.8766
1163 ANF 0.8766
1164 4KL 0.8765
1165 HX2 0.8765
1166 X48 0.8764
1167 MAE 0.8764
1168 PYC 0.8764
1169 2ZQ 0.8763
1170 EXO 0.8762
1171 2PC 0.8761
1172 MAQ 0.8761
1173 K17 0.8761
1174 HHS 0.8758
1175 E35 0.8757
1176 28N 0.8757
1177 4CH 0.8757
1178 2CZ 0.8756
1179 2QC 0.8755
1180 X09 0.8754
1181 39A 0.8754
1182 1L5 0.8754
1183 TBS 0.8752
1184 6DP 0.8751
1185 WOT 0.8750
1186 L7T 0.8749
1187 ARB 0.8749
1188 JZ1 0.8748
1189 6XI 0.8748
1190 PXY 0.8746
1191 AMG 0.8745
1192 M1H 0.8740
1193 L3Q 0.8738
1194 3YP 0.8736
1195 4LW 0.8736
1196 FCA 0.8735
1197 HQE 0.8735
1198 S24 0.8734
1199 N91 0.8734
1200 4HS 0.8733
1201 273 0.8731
1202 2TQ 0.8729
1203 PCR 0.8729
1204 PG3 0.8727
1205 J9W 0.8727
1206 GLY PRO 0.8726
1207 SIN 0.8726
1208 MSN 0.8725
1209 JRB 0.8724
1210 12M 0.8722
1211 I4B 0.8720
1212 3VX 0.8720
1213 G3P 0.8718
1214 G3H 0.8718
1215 GNM 0.8716
1216 8K2 0.8715
1217 M1Q 0.8715
1218 PLQ 0.8715
1219 265 0.8714
1220 URP 0.8714
1221 1X7 0.8714
1222 0TR 0.8714
1223 THA 0.8711
1224 2D3 0.8711
1225 CRS 0.8711
1226 JU2 0.8710
1227 PGH 0.8709
1228 SG2 0.8708
1229 CFA 0.8706
1230 1U6 0.8705
1231 I6G 0.8705
1232 680 0.8705
1233 RCO 0.8703
1234 UY7 0.8702
1235 4JN 0.8702
1236 MFB 0.8700
1237 463 0.8698
1238 ANC 0.8698
1239 B5D 0.8698
1240 152 0.8697
1241 S0E 0.8696
1242 FCB 0.8696
1243 FBF 0.8695
1244 G12 0.8695
1245 7B3 0.8695
1246 5NE 0.8695
1247 5WX 0.8695
1248 LG4 0.8688
1249 ADK 0.8687
1250 2KA 0.8684
1251 25R 0.8684
1252 APY 0.8682
1253 HNQ 0.8680
1254 IOL 0.8680
1255 NDM 0.8679
1256 K32 0.8679
1257 IP0 0.8678
1258 CEE 0.8678
1259 HKD 0.8678
1260 091 0.8677
1261 Q71 0.8677
1262 HGQ 0.8677
1263 OA3 0.8675
1264 JUG 0.8674
1265 XQK 0.8673
1266 KFH 0.8671
1267 BSP 0.8669
1268 FPN 0.8669
1269 GOO 0.8668
1270 KVP 0.8665
1271 4A5 0.8664
1272 RM4 0.8660
1273 86L 0.8660
1274 DNA 0.8659
1275 284 0.8659
1276 FHN 0.8658
1277 K6X 0.8658
1278 OTD 0.8658
1279 SYR 0.8657
1280 P9E 0.8656
1281 NDG 0.8656
1282 BPU 0.8653
1283 9KH 0.8652
1284 LDR 0.8650
1285 DA1 0.8650
1286 M6Z 0.8648
1287 HEW 0.8648
1288 2AS 0.8647
1289 F2W 0.8645
1290 LZ2 0.8643
1291 BP7 0.8643
1292 D07 0.8643
1293 0VT 0.8642
1294 M3T 0.8642
1295 B24 0.8641
1296 HXX 0.8640
1297 AES 0.8640
1298 H5B 0.8639
1299 P80 0.8639
1300 QBK 0.8639
1301 MFU 0.8638
1302 A9P 0.8638
1303 5NS 0.8637
1304 0OC 0.8637
1305 CK2 0.8636
1306 BNT 0.8634
1307 5CL 0.8634
1308 MOK 0.8633
1309 JAB 0.8633
1310 B3R 0.8631
1311 2CL 0.8631
1312 MZW 0.8630
1313 V1T 0.8627
1314 T9G 0.8625
1315 4NZ 0.8622
1316 HLD 0.8622
1317 3CH 0.8620
1318 6BL 0.8619
1319 68A 0.8617
1320 HA7 0.8617
1321 0GZ 0.8617
1322 DPT 0.8615
1323 7I2 0.8613
1324 CIT 0.8610
1325 4I8 0.8610
1326 AIN 0.8608
1327 DTL 0.8605
1328 5TY 0.8605
1329 X8D 0.8602
1330 K22 0.8600
1331 DRG 0.8594
1332 CIG 0.8594
1333 INS 0.8590
1334 64K 0.8587
1335 BVF 0.8584
1336 7ME 0.8583
1337 9AP 0.8582
1338 GP9 0.8581
1339 363 0.8579
1340 NCD 0.8578
1341 4H2 0.8577
1342 W81 0.8576
1343 KIB 0.8574
1344 3J8 0.8573
1345 JXW 0.8573
1346 KMY 0.8572
1347 K8X 0.8572
1348 3R4 0.8571
1349 DHC 0.8570
1350 MQB 0.8570
1351 6X9 0.8565
1352 E3D 0.8563
1353 EUE 0.8562
1354 JR2 0.8555
1355 FLC 0.8552
1356 9UL 0.8550
1357 PPT 0.8544
1358 XCG 0.8544
1359 DPZ 0.8543
1360 HHQ 0.8530
1361 TFU 0.8521
1362 S7J 0.8520
1363 JP2 0.8513
1364 57O 0.8511
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4K3P; Ligand: ACE GLN LEU ALA LEU PHE; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4k3p.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
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