Receptor
PDB id Resolution Class Description Source Keywords
4M8D 1.9 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF AN ISATIN HYDROLASE BOUND TO PRODUCT AN THIOISATINATE LABRENZIA AGGREGATA HYDROLASE ISATIN HYDROLYSIS THIOISATINATE (PRODUCT ANALOGU
Ref.: A PROTON WIRE AND WATER CHANNEL REVEALED IN THE CRY STRUCTURE OF ISATIN HYDROLASE. J.BIOL.CHEM. V. 289 21351 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MN G:301;
H:301;
L:301;
F:301;
D:301;
J:301;
B:301;
I:301;
C:301;
E:301;
A:301;
K:301;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
54.938 Mn [Mn+2...
CA D:303;
C:303;
F:303;
B:303;
A:304;
B:304;
L:305;
J:304;
L:303;
C:304;
L:304;
B:305;
A:305;
A:303;
I:303;
J:303;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Invalid;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Invalid;
Part of Protein;
Part of Protein;
Invalid;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
40.078 Ca [Ca+2...
23J B:302;
I:302;
H:302;
J:302;
L:302;
C:302;
A:302;
F:302;
K:302;
G:302;
D:302;
E:302;
 Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 ic50 ~ 10 uM
182.196 C8 H6 O3 S c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4M8D 1.9 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF AN ISATIN HYDROLASE BOUND TO PRODUCT AN THIOISATINATE LABRENZIA AGGREGATA HYDROLASE ISATIN HYDROLYSIS THIOISATINATE (PRODUCT ANALOGU
Ref.: A PROTON WIRE AND WATER CHANNEL REVEALED IN THE CRY STRUCTURE OF ISATIN HYDROLASE. J.BIOL.CHEM. V. 289 21351 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 4M8D ic50 ~ 10 uM 23J C8 H6 O3 S c1ccc(c(c1....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 4M8D ic50 ~ 10 uM 23J C8 H6 O3 S c1ccc(c(c1....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 214 families.
1 5NNB - 92K C8 H7 N O3 c1ccc(c(c1....
2 5NNA - BZM C14 H12 O2 c1ccc(cc1)....
3 4M8D ic50 ~ 10 uM 23J C8 H6 O3 S c1ccc(c(c1....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 23J; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 23J 1 1
2 JKE 0.625 0.75
3 92K 0.447368 0.612903
4 173 0.416667 0.652174
Similar Ligands (3D)
Ligand no: 1; Ligand: 23J; Similar ligands found: 1264
No: Ligand Similarity coefficient
1 R9S 0.9733
2 8OZ 0.9681
3 P7Y 0.9607
4 RMN 0.9573
5 9RW 0.9572
6 N2Z 0.9565
7 SHA 0.9558
8 52C 0.9556
9 SMN 0.9534
10 T9G 0.9497
11 61M 0.9492
12 1WC 0.9492
13 NVU 0.9490
14 5WY 0.9488
15 RAT 0.9485
16 6M4 0.9480
17 ICO 0.9472
18 TSR 0.9461
19 NCT 0.9458
20 EVA 0.9456
21 S24 0.9447
22 2FY 0.9445
23 2ZQ 0.9442
24 CFI 0.9435
25 Q6T 0.9435
26 GRO 0.9434
27 GZQ 0.9423
28 BGC 0.9421
29 HHH 0.9416
30 PZI 0.9414
31 GCB 0.9410
32 DEE 0.9409
33 BDP 0.9401
34 PRZ 0.9397
35 AKH 0.9395
36 15L 0.9391
37 M2K 0.9389
38 5RN 0.9386
39 ISZ 0.9374
40 GVG 0.9373
41 APG 0.9367
42 42C 0.9365
43 JF6 0.9363
44 46P 0.9363
45 LGC 0.9360
46 BHO 0.9358
47 8XQ 0.9356
48 FK8 0.9350
49 F06 0.9350
50 QY9 0.9349
51 GLC 0.9345
52 DS0 0.9344
53 QPR 0.9342
54 J9Q 0.9341
55 GCU 0.9339
56 MWP 0.9339
57 FBV 0.9333
58 1XA 0.9333
59 L13 0.9328
60 OMD 0.9323
61 PO6 0.9318
62 M4T 0.9317
63 LFC 0.9316
64 2CL 0.9315
65 CXP 0.9314
66 SAF 0.9314
67 NIZ 0.9314
68 OHP 0.9311
69 3SK 0.9309
70 E7Z 0.9306
71 2LY 0.9300
72 JRB 0.9299
73 K5W 0.9296
74 RNS 0.9294
75 G3F 0.9294
76 HA7 0.9290
77 8GK 0.9289
78 2PG 0.9281
79 XSP 0.9281
80 4ME 0.9280
81 HCI 0.9280
82 KTA 0.9279
83 2LP 0.9278
84 XYL 0.9277
85 RB5 0.9277
86 BNL 0.9277
87 HDH 0.9272
88 CFA 0.9271
89 DC5 0.9270
90 ISD 0.9269
91 I1E 0.9268
92 GCS 0.9268
93 UFV 0.9264
94 5NE 0.9263
95 A7W 0.9262
96 DIN 0.9261
97 FEH 0.9255
98 0LH 0.9254
99 SYM 0.9254
100 TTY 0.9254
101 2AL 0.9254
102 Q02 0.9251
103 A9P 0.9249
104 FB1 0.9247
105 FOT 0.9242
106 SYA 0.9241
107 97T 0.9241
108 SWA 0.9241
109 AL0 0.9241
110 DHY 0.9241
111 MXN 0.9237
112 PAC 0.9237
113 HC4 0.9235
114 EDR 0.9233
115 Z5P 0.9232
116 5RO 0.9230
117 PMB 0.9229
118 FBM 0.9228
119 4XV 0.9223
120 I3A 0.9223
121 SR4 0.9222
122 MNN 0.9222
123 BE2 0.9221
124 DHK 0.9220
125 8S0 0.9220
126 Q03 0.9219
127 R2P 0.9219
128 ASO 0.9219
129 7N0 0.9218
130 SAL 0.9218
131 F69 0.9217
132 TYL 0.9217
133 HLZ 0.9215
134 091 0.9212
135 BK9 0.9211
136 4AA 0.9211
137 IFP 0.9211
138 AAS 0.9211
139 F9P 0.9211
140 FB2 0.9210
141 HHT 0.9209
142 FBU 0.9208
143 1DJ 0.9207
144 PHU 0.9206
145 NOY 0.9205
146 HKD 0.9205
147 4XS 0.9205
148 CTL 0.9205
149 SAN 0.9201
150 MS9 0.9201
151 X0V 0.9200
152 IAC 0.9200
153 LNR 0.9195
154 4MU 0.9193
155 TVP 0.9189
156 MHK 0.9188
157 0W8 0.9188
158 IJZ 0.9188
159 DBX 0.9188
160 51R 0.9188
161 49O 0.9185
162 J9T 0.9185
163 3YP 0.9184
164 GLU 0.9183
165 FA3 0.9182
166 FBT 0.9181
167 5NI 0.9180
168 FBW 0.9180
169 N3W 0.9178
170 5RG 0.9174
171 GTQ 0.9173
172 MJ2 0.9173
173 EKZ 0.9173
174 URS 0.9172
175 CN0 0.9171
176 A13 0.9171
177 4HP 0.9171
178 GLT 0.9170
179 069 0.9169
180 QIC 0.9168
181 7WV 0.9166
182 7ZE 0.9165
183 O2A 0.9163
184 5IQ 0.9163
185 3U4 0.9161
186 ROR 0.9160
187 3AL 0.9159
188 DBJ 0.9158
189 LSA 0.9157
190 45L 0.9156
191 4TU 0.9155
192 MRW 0.9155
193 4SV 0.9155
194 ICB 0.9155
195 TSS 0.9154
196 54G 0.9154
197 BSX 0.9154
198 4VY 0.9153
199 FA1 0.9153
200 IFL 0.9151
201 HNL 0.9151
202 7VS 0.9150
203 M5H 0.9150
204 KBB 0.9150
205 4NC 0.9150
206 5M0 0.9148
207 KBG 0.9148
208 C2U 0.9148
209 A29 0.9148
210 SHG 0.9147
211 4Z4 0.9146
212 FE DB1 0.9146
213 9TZ 0.9145
214 S2P 0.9144
215 APZ 0.9143
216 M1H 0.9143
217 4FH 0.9143
218 M0W 0.9142
219 8CM 0.9142
220 RM1 0.9142
221 6M9 0.9141
222 XCZ 0.9141
223 7HQ 0.9140
224 3M0 0.9139
225 9RH 0.9139
226 G5V 0.9139
227 PMF 0.9139
228 DBH 0.9138
229 OA3 0.9137
230 JZ4 0.9137
231 ISN 0.9136
232 D1X 0.9135
233 FCR 0.9135
234 3F0 0.9134
235 0JD 0.9133
236 C2Y 0.9133
237 5HY 0.9133
238 3HA 0.9132
239 7NI 0.9132
240 5OB 0.9129
241 3SL 0.9128
242 OGA 0.9128
243 OCH 0.9126
244 EA1 0.9126
245 34D 0.9125
246 1WD 0.9125
247 BZ3 0.9125
248 ODO 0.9125
249 COU 0.9124
250 PXL 0.9124
251 2FG 0.9121
252 VNJ 0.9121
253 92P 0.9118
254 BCU 0.9117
255 ORO 0.9117
256 BCK 0.9115
257 5SG 0.9114
258 AMS 0.9114
259 NOJ 0.9114
260 24W 0.9114
261 4JT 0.9114
262 0P6 0.9114
263 AHN 0.9113
264 PHE 0.9111
265 C9E 0.9111
266 BNT 0.9107
267 FBS 0.9107
268 3MG 0.9107
269 SBK 0.9106
270 HQY 0.9105
271 GTR 0.9105
272 ES6 0.9105
273 HNQ 0.9104
274 3DO 0.9104
275 42A 0.9103
276 9PY 0.9103
277 GAL 0.9103
278 PSJ 0.9102
279 CWS 0.9102
280 GBN 0.9102
281 IOS 0.9101
282 3FH 0.9101
283 XM0 0.9101
284 GLN 0.9101
285 HA5 0.9100
286 FP1 0.9100
287 MUC 0.9099
288 RNT 0.9098
289 1F1 0.9098
290 SRO 0.9097
291 KFH 0.9097
292 GLO 0.9096
293 TSU 0.9096
294 TAR 0.9095
295 3C4 0.9095
296 EYK 0.9093
297 N5J 0.9093
298 4XH 0.9093
299 HDL 0.9091
300 KUF 0.9090
301 9KH 0.9090
302 ASC 0.9089
303 261 0.9089
304 TT4 0.9089
305 2F6 0.9087
306 G2F 0.9087
307 Q24 0.9086
308 5CU 0.9086
309 03V 0.9085
310 6OT 0.9085
311 URC 0.9085
312 M4E 0.9084
313 A09 0.9084
314 KDG 0.9084
315 2AQ 0.9083
316 8ZE 0.9082
317 HJP 0.9082
318 SHI 0.9080
319 268 0.9080
320 1SQ 0.9080
321 XBT 0.9079
322 AKG 0.9077
323 MQB 0.9076
324 ES5 0.9075
325 GCO 0.9075
326 1LN 0.9075
327 S8D 0.9074
328 HH8 0.9073
329 4HC 0.9072
330 LT8 0.9072
331 HJH 0.9071
332 AZ8 0.9071
333 AJ2 0.9070
334 IP0 0.9070
335 4SX 0.9069
336 60Q 0.9069
337 DOR 0.9069
338 ROI 0.9068
339 4J8 0.9068
340 TLA 0.9067
341 M1E 0.9066
342 NDH 0.9066
343 3IT 0.9065
344 M3H 0.9065
345 DOB 0.9065
346 57O 0.9065
347 44V 0.9064
348 4FS 0.9063
349 KKN 0.9063
350 X09 0.9063
351 9MG 0.9063
352 L99 0.9063
353 3BU 0.9062
354 SRT 0.9062
355 2ZM 0.9062
356 M6N 0.9061
357 G3E 0.9061
358 MTL 0.9061
359 6ME 0.9061
360 PPY 0.9060
361 4YS 0.9060
362 QMP 0.9059
363 M5K 0.9059
364 K7M 0.9059
365 TPA 0.9058
366 LYL 0.9058
367 FA0 0.9057
368 TZE 0.9057
369 OTR 0.9056
370 JKZ 0.9056
371 3PF 0.9056
372 IPM 0.9055
373 6GU 0.9054
374 2EC 0.9054
375 I4B 0.9054
376 AZ9 0.9053
377 ZZZ 0.9051
378 5NS 0.9051
379 TAG 0.9050
380 MR1 0.9050
381 KT7 0.9050
382 DQA 0.9050
383 LZM 0.9049
384 BHA 0.9049
385 HXX 0.9048
386 5WV 0.9048
387 CTS 0.9048
388 XQG 0.9047
389 NLA 0.9047
390 263 0.9047
391 GDE 0.9047
392 VNL 0.9046
393 F52 0.9046
394 HL5 0.9046
395 NFA 0.9046
396 7Q1 0.9046
397 H42 0.9045
398 F05 0.9045
399 FUD 0.9045
400 7MU 0.9045
401 DGL 0.9044
402 AIN 0.9043
403 PE0 0.9043
404 HIS 0.9043
405 SYC 0.9042
406 GZ3 0.9041
407 ES7 0.9041
408 AOS 0.9040
409 94B 0.9040
410 JBQ 0.9040
411 AQO 0.9038
412 LT2 0.9038
413 HIO 0.9038
414 CXF 0.9038
415 3OC 0.9037
416 JBE 0.9036
417 HFA 0.9035
418 HQ9 0.9034
419 MSR 0.9034
420 5XC 0.9033
421 ES1 0.9033
422 0QW 0.9033
423 8XL 0.9031
424 5QX 0.9031
425 5QY 0.9031
426 0RW 0.9030
427 PPT 0.9030
428 SVN 0.9029
429 HQT 0.9029
430 6NI 0.9028
431 PIY 0.9028
432 EGR 0.9028
433 R9Y 0.9027
434 1LQ 0.9026
435 3A9 0.9026
436 HF2 0.9025
437 AEG 0.9024
438 6XI 0.9024
439 RJY 0.9023
440 PXM 0.9023
441 DHB 0.9023
442 KDF 0.9023
443 3WA 0.9022
444 5MK 0.9021
445 82I 0.9021
446 QDK 0.9020
447 QUS 0.9019
448 ADA 0.9018
449 DE5 0.9017
450 UEG 0.9017
451 NNO 0.9017
452 DHI 0.9017
453 NID 0.9016
454 NCD 0.9016
455 RD4 0.9015
456 5NU 0.9015
457 5Q0 0.9015
458 JPZ 0.9015
459 SYG 0.9013
460 264 0.9012
461 HLR 0.9012
462 INO 0.9010
463 PEQ 0.9010
464 0V5 0.9010
465 15N 0.9009
466 149 0.9009
467 NYL 0.9009
468 0FK 0.9008
469 KJU 0.9008
470 SE2 0.9007
471 3Z8 0.9007
472 ES0 0.9006
473 J9W 0.9006
474 DHS 0.9006
475 7W4 0.9005
476 LKA 0.9004
477 PEP 0.9004
478 2D0 0.9003
479 2SX 0.9003
480 LZ2 0.9002
481 ONR 0.9002
482 JB8 0.9000
483 MEW 0.9000
484 MO8 0.9000
485 SYV 0.8998
486 2H5 0.8998
487 BNF 0.8998
488 S8V 0.8997
489 Q88 0.8997
490 JDN 0.8994
491 3NY 0.8993
492 AMQ 0.8992
493 258 0.8992
494 RXA 0.8992
495 J0Z 0.8990
496 L7T 0.8990
497 NQ 0.8990
498 JB5 0.8989
499 X05 0.8989
500 HY1 0.8989
501 UNC 0.8988
502 5WX 0.8988
503 6VD 0.8987
504 NFM 0.8987
505 GJZ 0.8987
506 6AP 0.8986
507 3QM 0.8985
508 SKA 0.8985
509 MT5 0.8985
510 PFB 0.8985
511 YPN 0.8984
512 PA1 0.8984
513 5VL 0.8984
514 B62 0.8984
515 6NT 0.8984
516 IPB 0.8984
517 HPS 0.8983
518 RUY 0.8983
519 HNH 0.8983
520 4M0 0.8982
521 KGK 0.8982
522 DPN 0.8982
523 BEA 0.8982
524 PJW 0.8982
525 AZA 0.8982
526 JBK 0.8981
527 GGL 0.8981
528 ABI 0.8981
529 8G0 0.8980
530 BEZ 0.8980
531 FAN 0.8979
532 1GN 0.8978
533 2HG 0.8978
534 B85 0.8977
535 HHA 0.8977
536 9EW 0.8977
537 ALL 0.8977
538 D48 0.8976
539 269 0.8976
540 DRL 0.8975
541 KP6 0.8974
542 CBF 0.8973
543 M1A 0.8973
544 GIV 0.8971
545 J5I 0.8971
546 ZBT 0.8971
547 PDC 0.8971
548 0OC 0.8970
549 LCN 0.8970
550 GOX 0.8970
551 1NP 0.8970
552 DGN 0.8969
553 R67 0.8969
554 TZL 0.8968
555 NIO 0.8968
556 FTV 0.8967
557 XAZ 0.8967
558 M1Q 0.8967
559 DX4 0.8967
560 SDF 0.8967
561 GCW 0.8966
562 54D 0.8965
563 75K 0.8965
564 DIU 0.8965
565 53C 0.8965
566 GUN 0.8965
567 0F9 0.8965
568 CWM 0.8964
569 MT0 0.8964
570 535 0.8964
571 EQT 0.8963
572 HZQ 0.8962
573 1X7 0.8961
574 5WU 0.8961
575 QBS 0.8961
576 0N7 0.8961
577 M0Q 0.8960
578 495 0.8960
579 ADZ 0.8960
580 UFO 0.8959
581 I38 0.8959
582 VK3 0.8959
583 GLF 0.8957
584 FBJ 0.8957
585 ABV 0.8957
586 7CT 0.8957
587 NPO 0.8957
588 E35 0.8956
589 BEN 0.8956
590 GAB 0.8955
591 XAN 0.8955
592 SX1 0.8954
593 FGZ 0.8953
594 PRY 0.8953
595 QSH 0.8953
596 505 0.8952
597 F31 0.8951
598 KYA 0.8951
599 3ID 0.8951
600 INE 0.8949
601 290 0.8949
602 PIM 0.8948
603 1P7 0.8948
604 2FT 0.8948
605 ICT 0.8947
606 GRE 0.8947
607 8TX 0.8947
608 NCA 0.8946
609 FBG 0.8945
610 0HO 0.8944
611 XUL 0.8943
612 CH9 0.8943
613 TTL 0.8942
614 GYE 0.8942
615 UAN 0.8942
616 7QS 0.8942
617 2KA 0.8941
618 7MX 0.8941
619 6PC 0.8941
620 JTH 0.8940
621 HQD 0.8939
622 RSO 0.8939
623 N2I 0.8938
624 BAM 0.8938
625 QM1 0.8938
626 SKM 0.8937
627 14O 0.8937
628 N8Y 0.8937
629 HH5 0.8937
630 3HB 0.8937
631 9ZE 0.8936
632 M6W 0.8936
633 A2F 0.8935
634 K34 0.8935
635 2CK 0.8935
636 G1O 0.8935
637 7W1 0.8935
638 TIU 0.8934
639 25W 0.8932
640 9FL 0.8932
641 IGA 0.8931
642 ZXD 0.8931
643 5XB 0.8930
644 6CS 0.8930
645 2C2 0.8930
646 1SA 0.8930
647 FIX 0.8930
648 OVV 0.8930
649 OXC 0.8930
650 RHU 0.8930
651 DNF 0.8929
652 2IT 0.8929
653 141 0.8929
654 B40 0.8928
655 86J 0.8928
656 791 0.8927
657 A9O 0.8927
658 5H1 0.8925
659 CFP 0.8924
660 IV2 0.8924
661 SJ5 0.8924
662 PHB 0.8924
663 PZA 0.8924
664 5HN 0.8923
665 GCV 0.8923
666 3C2 0.8922
667 JXZ 0.8921
668 F60 0.8921
669 SXS 0.8921
670 7WG 0.8921
671 RBJ 0.8921
672 5AC 0.8920
673 DX3 0.8920
674 II6 0.8919
675 NBZ 0.8919
676 JUG 0.8918
677 DPZ 0.8917
678 5B1 0.8917
679 PH3 0.8917
680 XDE 0.8916
681 GAG 0.8916
682 4YO 0.8916
683 AJV 0.8915
684 O72 0.8915
685 PBC 0.8915
686 HQJ 0.8915
687 CFF 0.8914
688 XXG 0.8914
689 QUZ 0.8914
690 SPA 0.8914
691 0HN 0.8913
692 NTM 0.8913
693 5GU 0.8913
694 LPK 0.8912
695 MYJ 0.8912
696 JAE 0.8911
697 F12 0.8911
698 93K 0.8911
699 BZX 0.8911
700 3AB 0.8911
701 YCP 0.8911
702 SS1 0.8911
703 2K4 0.8910
704 1AL 0.8910
705 12Q 0.8910
706 9BF 0.8910
707 PBA 0.8910
708 SOE 0.8910
709 8WT 0.8909
710 1A7 0.8909
711 SOR 0.8909
712 56D 0.8908
713 TIH 0.8908
714 HNK 0.8908
715 CPZ 0.8908
716 GZL 0.8907
717 P84 0.8906
718 2HO 0.8906
719 4HM 0.8905
720 67N 0.8905
721 FDK 0.8905
722 YRL 0.8905
723 K3Q 0.8904
724 AC6 0.8904
725 6HO 0.8904
726 MAJ 0.8903
727 PFL 0.8903
728 P9P 0.8902
729 4CS 0.8902
730 YSO 0.8901
731 4JQ 0.8901
732 67X 0.8900
733 NMJ 0.8900
734 67Y 0.8897
735 WOO 0.8897
736 60P 0.8897
737 3MB 0.8897
738 NTN 0.8897
739 AC0 0.8895
740 GAF 0.8895
741 DAL DAL 0.8895
742 B55 0.8894
743 6M1 0.8893
744 VGL 0.8893
745 4A3 0.8892
746 AHR 0.8892
747 MLT 0.8892
748 DMD 0.8890
749 GOG 0.8890
750 AZG 0.8890
751 7B4 0.8890
752 6MP 0.8890
753 41K 0.8890
754 4FA 0.8890
755 3HM 0.8889
756 ARP 0.8889
757 9DG 0.8889
758 5JQ 0.8888
759 GLA 0.8887
760 CLU 0.8887
761 UNU 0.8886
762 X6X 0.8886
763 PQK 0.8885
764 329 0.8885
765 6AI 0.8885
766 OVM 0.8885
767 AEF 0.8884
768 2O6 0.8884
769 10L 0.8884
770 M58 0.8883
771 MBG 0.8882
772 BMA 0.8881
773 YIO 0.8881
774 7FF 0.8881
775 RBL 0.8880
776 PAB 0.8880
777 LDP 0.8878
778 PD2 0.8878
779 APS 0.8877
780 1BN 0.8877
781 FHB 0.8877
782 YH7 0.8877
783 271 0.8877
784 6F0 0.8876
785 SQ7 0.8876
786 XYP 0.8875
787 2HU 0.8874
788 MAN 0.8874
789 CLZ 0.8874
790 KLW 0.8873
791 IPZ 0.8873
792 ASP 0.8873
793 XX2 0.8872
794 NPY 0.8872
795 SVD 0.8872
796 GWM 0.8871
797 HPA 0.8870
798 2TQ 0.8870
799 LXC 0.8870
800 BTY 0.8869
801 SEP 0.8869
802 3NT 0.8868
803 JFJ 0.8867
804 2HQ 0.8867
805 JAW 0.8867
806 3HG 0.8866
807 A3M 0.8866
808 XIY 0.8865
809 K2P 0.8865
810 FRU 0.8865
811 OXQ 0.8865
812 152 0.8864
813 5MI 0.8862
814 AFR 0.8862
815 GOJ 0.8861
816 39A 0.8861
817 3HP 0.8861
818 GTL 0.8860
819 NGO 0.8856
820 1LM 0.8856
821 8W9 0.8854
822 12B 0.8854
823 23A 0.8854
824 DFB 0.8854
825 2BG 0.8853
826 MIG 0.8853
827 JBH 0.8853
828 GBD 0.8852
829 SR1 0.8852
830 BZJ 0.8850
831 1L5 0.8850
832 6R8 0.8850
833 1Y6 0.8850
834 G6D 0.8849
835 HBD 0.8849
836 MUA 0.8848
837 MAQ 0.8848
838 XQ0 0.8848
839 5MB 0.8848
840 8NX 0.8848
841 FLV 0.8847
842 226 0.8847
843 SDD 0.8847
844 PHT 0.8846
845 JZ7 0.8845
846 AX7 0.8845
847 270 0.8845
848 F5B 0.8845
849 6LW 0.8845
850 P72 0.8845
851 PEL 0.8845
852 32X 0.8844
853 2AS 0.8844
854 DHR 0.8843
855 9SE 0.8843
856 NSG 0.8842
857 FF3 0.8842
858 OAA 0.8842
859 AW5 0.8840
860 B60 0.8840
861 7WA 0.8840
862 DHQ 0.8840
863 9TW 0.8840
864 B09 0.8840
865 6FZ 0.8840
866 F9Y 0.8839
867 948 0.8839
868 V55 0.8838
869 4PN 0.8838
870 ONL 0.8838
871 TFU 0.8837
872 BP1 0.8837
873 ET2 0.8836
874 EOL 0.8836
875 293 0.8835
876 1P3 0.8835
877 PBZ 0.8835
878 AHC 0.8834
879 GV9 0.8833
880 TRP 0.8832
881 KTJ 0.8832
882 JLZ 0.8831
883 FDB 0.8831
884 SNU 0.8831
885 EHM 0.8830
886 N4B 0.8830
887 XLS 0.8830
888 DGJ 0.8829
889 2MI 0.8829
890 PEZ 0.8829
891 PEA 0.8828
892 9UL 0.8827
893 FXH 0.8827
894 ZWZ 0.8826
895 4P5 0.8826
896 BNS 0.8825
897 QSB 0.8825
898 0CU 0.8824
899 6DP 0.8823
900 GXL 0.8822
901 EN1 0.8822
902 4MA 0.8822
903 ZZ8 0.8821
904 TZF 0.8821
905 BE7 0.8820
906 GXY 0.8820
907 QX2 0.8820
908 G3H 0.8820
909 G3P 0.8820
910 8WO 0.8820
911 EXO 0.8819
912 KOJ 0.8818
913 GLY PRO 0.8817
914 717 0.8817
915 AS3 0.8817
916 DTR 0.8816
917 37T 0.8814
918 CS2 0.8814
919 2BX 0.8813
920 8IG 0.8813
921 6TZ 0.8813
922 TOF 0.8811
923 IFM 0.8811
924 8GC 0.8811
925 FA6 0.8811
926 7UC 0.8811
927 9R5 0.8808
928 61O 0.8808
929 7ME 0.8806
930 TEO 0.8806
931 SLC 0.8805
932 D07 0.8805
933 EXD 0.8803
934 R8V 0.8803
935 1DV 0.8803
936 IWT 0.8803
937 QSC 0.8801
938 F1A 0.8801
939 MCO 0.8801
940 M5N 0.8800
941 NGT 0.8800
942 NGW 0.8800
943 D3M 0.8800
944 1DW 0.8799
945 PEY 0.8799
946 BTE 0.8799
947 3BZ 0.8799
948 MNP 0.8799
949 HL4 0.8798
950 QX4 0.8798
951 2ZV 0.8797
952 3C1 0.8797
953 3DM 0.8797
954 NHG 0.8797
955 L5V 0.8797
956 42J 0.8796
957 4NG 0.8795
958 SS2 0.8794
959 7WR 0.8793
960 2AK 0.8793
961 5OF 0.8792
962 PRA 0.8792
963 EV0 0.8792
964 9KT 0.8792
965 EUG 0.8792
966 4M4 0.8791
967 1IT 0.8789
968 M3Q 0.8788
969 51F 0.8787
970 X8D 0.8786
971 E1P 0.8785
972 826 0.8785
973 PKU 0.8785
974 FHC 0.8785
975 G4D 0.8785
976 SD4 0.8784
977 JZ3 0.8784
978 1XN 0.8783
979 Z82 0.8783
980 IHB 0.8782
981 S2G 0.8782
982 1QP 0.8781
983 LI6 0.8780
984 TRA 0.8780
985 CHB 0.8780
986 CIT 0.8780
987 11S 0.8779
988 X8Z 0.8779
989 8VN 0.8779
990 OK7 0.8779
991 1P8 0.8778
992 M74 0.8777
993 S76 0.8777
994 HSO 0.8776
995 54X 0.8775
996 1XM 0.8775
997 4RW 0.8775
998 EPR 0.8775
999 XEN 0.8775
1000 9CA 0.8774
1001 8U3 0.8773
1002 4P0 0.8772
1003 5JL 0.8771
1004 DIE 0.8770
1005 7VP 0.8770
1006 TGX 0.8769
1007 ES9 0.8769
1008 KYD 0.8769
1009 MQN 0.8768
1010 TZM 0.8768
1011 F0J 0.8768
1012 DHC 0.8767
1013 HMU 0.8767
1014 J9N 0.8766
1015 GT0 0.8765
1016 24B 0.8765
1017 KJY 0.8764
1018 IF7 0.8763
1019 8K2 0.8763
1020 3C7 0.8763
1021 FBB 0.8762
1022 BRT 0.8762
1023 SQ4 0.8762
1024 MNM 0.8759
1025 0TU 0.8758
1026 C5A 0.8758
1027 ZZ2 0.8758
1028 2FQ 0.8756
1029 ES2 0.8756
1030 JA8 0.8755
1031 KJH 0.8755
1032 ASN 0.8755
1033 3PG 0.8753
1034 TQU 0.8753
1035 CRN 0.8752
1036 4AV 0.8752
1037 ZON 0.8752
1038 39U 0.8751
1039 HMH 0.8751
1040 NDM 0.8751
1041 LMR 0.8750
1042 ESI 0.8750
1043 6J9 0.8749
1044 9DA 0.8748
1045 PRF 0.8747
1046 G8M 0.8747
1047 1U6 0.8747
1048 AVI 0.8747
1049 TYE 0.8747
1050 BCP 0.8745
1051 PYQ 0.8745
1052 ES4 0.8745
1053 BOA 0.8744
1054 2A7 0.8744
1055 7HP 0.8744
1056 FLC 0.8743
1057 4ZC 0.8743
1058 PBN 0.8742
1059 36M 0.8741
1060 1M2 0.8740
1061 SW7 0.8740
1062 JR2 0.8740
1063 209 0.8738
1064 9HX 0.8738
1065 WCE 0.8737
1066 R8S 0.8737
1067 TH7 0.8737
1068 BPS 0.8737
1069 6BL 0.8736
1070 XHP 0.8734
1071 39O 0.8733
1072 KIB 0.8732
1073 FYU 0.8731
1074 KDV 0.8730
1075 MP5 0.8730
1076 PHH 0.8729
1077 GIO 0.8728
1078 RIB 0.8727
1079 B57 0.8727
1080 E1T 0.8727
1081 3MF 0.8727
1082 36E 0.8726
1083 174 0.8725
1084 LAO 0.8725
1085 PM6 0.8725
1086 SF9 0.8724
1087 CLW 0.8722
1088 3MA 0.8722
1089 QWW 0.8722
1090 4XR 0.8722
1091 K2T 0.8721
1092 KIA 0.8721
1093 0FO 0.8720
1094 REL 0.8720
1095 C1M 0.8720
1096 YZM 0.8719
1097 LT1 0.8718
1098 ZZT 0.8717
1099 I6G 0.8716
1100 MVN 0.8716
1101 B53 0.8714
1102 8HC 0.8714
1103 DCO 0.8714
1104 ZB1 0.8712
1105 H4N 0.8710
1106 HX3 0.8710
1107 P92 0.8708
1108 TYR 0.8708
1109 OTW 0.8707
1110 44W 0.8707
1111 1WG 0.8706
1112 ADE 0.8705
1113 IT2 0.8704
1114 PYU 0.8704
1115 DNC 0.8703
1116 2D8 0.8703
1117 FK1 0.8702
1118 7MK 0.8702
1119 0A9 0.8702
1120 B2J 0.8702
1121 R20 0.8701
1122 3RK 0.8701
1123 EJZ 0.8700
1124 F6P 0.8699
1125 DQU 0.8699
1126 NSP 0.8698
1127 FUL 0.8698
1128 13P 0.8698
1129 DMJ 0.8697
1130 GLY CYS 0.8696
1131 DAS 0.8696
1132 I3E 0.8695
1133 VXX 0.8695
1134 MVL 0.8695
1135 HPP 0.8695
1136 LLQ 0.8695
1137 F34 0.8691
1138 6RQ 0.8691
1139 WOT 0.8690
1140 TEP 0.8689
1141 M5E 0.8689
1142 5CL 0.8687
1143 ORN 0.8687
1144 94W 0.8686
1145 LEU 0.8686
1146 CWJ 0.8685
1147 9FE 0.8684
1148 VGD 0.8683
1149 PH2 0.8683
1150 NAG 0.8683
1151 M45 0.8682
1152 AX3 0.8681
1153 B0D 0.8681
1154 JND 0.8680
1155 36R 0.8679
1156 ESP 0.8679
1157 QBK 0.8678
1158 E7R 0.8678
1159 7B3 0.8677
1160 AMH 0.8677
1161 DYA 0.8676
1162 ADK 0.8675
1163 AMG 0.8675
1164 M3S 0.8675
1165 TPO 0.8674
1166 R8A 0.8674
1167 F4E 0.8674
1168 OXZ 0.8673
1169 1FF 0.8673
1170 IND 0.8672
1171 SLY 0.8671
1172 JYD 0.8670
1173 SC2 0.8668
1174 KTW 0.8667
1175 680 0.8666
1176 BDF 0.8666
1177 2UB 0.8665
1178 COI 0.8664
1179 NBG 0.8662
1180 NK 0.8662
1181 GUA 0.8662
1182 5ZZ 0.8661
1183 0W1 0.8660
1184 2CZ 0.8657
1185 HY3 0.8657
1186 ISE 0.8656
1187 DTY 0.8655
1188 XXR 0.8652
1189 S2T 0.8650
1190 2RH 0.8649
1191 GP9 0.8649
1192 286 0.8648
1193 790 0.8647
1194 LT3 0.8646
1195 HBA 0.8645
1196 40E 0.8645
1197 8H8 0.8644
1198 9AP 0.8642
1199 LDR 0.8640
1200 AZF 0.8640
1201 36Y 0.8640
1202 1KP 0.8639
1203 IDM 0.8639
1204 E0O 0.8638
1205 BZ2 0.8637
1206 E4P 0.8636
1207 INS 0.8634
1208 JZA 0.8631
1209 YIE 0.8631
1210 ZYR 0.8629
1211 7D2 0.8628
1212 4WL 0.8627
1213 4KL 0.8623
1214 LYS 0.8621
1215 PQ0 0.8620
1216 4OG 0.8620
1217 ICF 0.8619
1218 MT8 0.8616
1219 1PT 0.8616
1220 8GL 0.8612
1221 30G 0.8607
1222 15E 0.8607
1223 SPV 0.8607
1224 XYS 0.8607
1225 SLS 0.8606
1226 1DQ 0.8605
1227 C2A 0.8603
1228 QBM 0.8603
1229 0XT 0.8601
1230 S3C 0.8601
1231 2DR 0.8599
1232 4ZA 0.8598
1233 P3K 0.8597
1234 LFR 0.8596
1235 V6F 0.8596
1236 SMV 0.8594
1237 QWN 0.8593
1238 9X5 0.8592
1239 HX4 0.8591
1240 12M 0.8591
1241 NTZ 0.8589
1242 3XX 0.8588
1243 MZB 0.8584
1244 J6W 0.8582
1245 K17 0.8581
1246 JZ5 0.8578
1247 RM4 0.8575
1248 4A5 0.8572
1249 3TJ 0.8571
1250 JXN 0.8571
1251 ITN 0.8566
1252 H33 0.8561
1253 0R0 0.8559
1254 J4K 0.8558
1255 KIF 0.8556
1256 DQN 0.8551
1257 TNX 0.8545
1258 S3B 0.8545
1259 N1E 0.8544
1260 IBM 0.8540
1261 Q7A 0.8530
1262 TWO 0.8530
1263 FQI 0.8526
1264 ISA 0.8521
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4m8d.bio4) has 14 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4m8d.bio4) has 14 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4m8d.bio2) has 14 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4m8d.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 4m8d.bio5) has 14 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4m8d.bio5) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 4m8d.bio3) has 14 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 4m8d.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 4m8d.bio6) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 4m8d.bio6) has 14 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 4m8d.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 4M8D; Ligand: 23J; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 4m8d.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
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