Receptor
PDB id Resolution Class Description Source Keywords
4M69 2.5 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF THE MOUSE RIP3-MLKL COMPLEX MUS MUSCULUS KINASE PHOSPHORYLATION TRANSFERASE-SIGNALING PROTEIN COMPL
Ref.: STRUCTURAL INSIGHTS INTO RIP3-MEDIATED NECROPTOTIC CELL REP V. 5 70 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:405;
A:404;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
ANP A:401;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
SO4 B:501;
A:402;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
MG A:403;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4M69 2.5 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF THE MOUSE RIP3-MLKL COMPLEX MUS MUSCULUS KINASE PHOSPHORYLATION TRANSFERASE-SIGNALING PROTEIN COMPL
Ref.: STRUCTURAL INSIGHTS INTO RIP3-MEDIATED NECROPTOTIC CELL REP V. 5 70 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 4M69 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 4M69 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 4M69 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4M69; Ligand: ANP; Similar sites found: 306
This union binding pocket(no: 1) in the query (biounit: 4m69.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1I7L ATP 0.0003058 0.43695 1.76678
2 4FE2 ADP 0.001816 0.4447 2.7451
3 2PYW ADP 0.0001054 0.47584 2.8754
4 1EHI ADP 0.005385 0.40695 2.8754
5 3TDV GDP 0.00001534 0.52288 2.94118
6 3TY3 GGG 0.00476 0.43934 3.18021
7 1X54 4AD 0.009041 0.4006 3.18021
8 3ZJX BOG 0.0007443 0.48412 3.19489
9 1PK8 ATP 0.0002128 0.43639 3.51438
10 1TDF NAP 0.01052 0.43532 3.53357
11 1MJT ITU 0.006505 0.42919 3.53357
12 2IYF UDP 0.02024 0.40273 3.53357
13 1AUX AGS 0.0002518 0.46925 3.53698
14 3VPD ANP 0.004802 0.4014 3.55872
15 1Q8P MAN MMA 0.0225 0.40462 3.57143
16 1Q8O MAN MMA 0.02812 0.40028 3.57143
17 1NXJ TLA 0.01164 0.42244 3.82514
18 4CYI ATP 0.0000393 0.49396 3.88693
19 2PUL ACP 0.0003501 0.46785 3.88693
20 3PNA CMP 0.02273 0.4002 3.8961
21 3JUC PCA 0.002856 0.45252 3.92157
22 5C1P ADP 0.005126 0.40096 3.92157
23 5MRH Q9Z 0.004885 0.43357 4.15335
24 2YW2 ATP 0.006026 0.40149 4.15335
25 5T96 79J 0.006488 0.43729 4.24028
26 2IF8 ADP 0.006347 0.43284 4.24028
27 3VPC ADP 0.001767 0.41854 4.25532
28 3VPB ADP 0.001046 0.41476 4.25532
29 5A5W GUO 0.01756 0.40434 4.34783
30 4PZ6 GMP 0.008984 0.42317 4.59364
31 3K5I ADP 0.002257 0.41956 4.59364
32 4UBS DIF 0.01727 0.41136 4.59364
33 1H3F TYE 0.02193 0.40152 4.59364
34 3NOJ PYR 0.01473 0.42103 4.62185
35 5MW8 ATP 0.00000155 0.55864 4.79233
36 4LH7 1X8 0.002059 0.46105 4.79233
37 3KV4 OGA 0.01901 0.41016 4.79233
38 1Y7P RIP 0.01339 0.41072 4.93274
39 4CC6 L5Y 0.005255 0.432 4.947
40 3DNT ATP 0.002146 0.40394 4.947
41 4FBL SPD 0.01387 0.41095 4.98221
42 1DZK PRZ 0.001382 0.44093 5.09554
43 1J78 OLA 0.03166 0.41578 5.11182
44 1SGJ OAA 0.005553 0.4126 5.11182
45 5IQD GNP 0.0002485 0.48395 5.30035
46 5IQD RIO 0.0002659 0.48395 5.30035
47 3BP1 GUN 0.02238 0.41744 5.30035
48 2IO8 ADP 0.001625 0.41013 5.30035
49 1IA9 ANP 0.000001084 0.56662 5.35714
50 2VQD AP2 0.0002584 0.45937 5.43131
51 4RDL FUC GAL NDG FUC 0.01092 0.42332 5.65371
52 1YOA FMN 0.02265 0.41037 5.66038
53 4XBT 3ZQ 0.004698 0.42516 5.80645
54 4XBT FLC 0.007398 0.4044 5.80645
55 4OAV ACP 0.0000001018 0.6274 6.00707
56 4ZS4 ATP 0.0000003422 0.58823 6.00707
57 1UWK NAD 0.01295 0.41581 6.00707
58 4MV1 ADP 0.01167 0.40385 6.00707
59 3ORQ ADP 0.002766 0.41582 6.1008
60 3PDT ADP 0.000001495 0.58241 6.18182
61 1CBK ROI 0.008095 0.43011 6.25
62 5FCF GLY GLY GLY 0.00322 0.45075 6.36042
63 3B2Q AES 0.03317 0.40312 6.36042
64 2Q7D ANP 0.00517 0.41268 6.38978
65 4JGP PYR 0.01766 0.41239 6.38978
66 5W2I ADP 0.00141 0.43384 6.61479
67 5W2I I3P 0.00141 0.43384 6.61479
68 4IX4 ADP 0.0005552 0.44533 6.70927
69 5C4L SIS 0.00005809 0.50465 6.71378
70 5C4L 4XR 0.00006531 0.50239 6.71378
71 4GYI ADP 0.001032 0.4563 6.71378
72 4DFU QUE 0.008991 0.42509 6.71378
73 3VV1 GAL FUC 0.01761 0.40981 6.875
74 1M0W ANP 0.006404 0.4147 7.02875
75 2XSB GDL 0.02016 0.40281 7.02875
76 1GMN IDS SGN IDS SGN IDS 0.01874 0.41203 7.10383
77 1TZD ADP 0.01241 0.41559 7.27273
78 5ML3 DL3 0.01555 0.40379 7.38255
79 3SAO NKN 0.01788 0.40139 7.5
80 2GQS ADP 0.0007694 0.45242 7.59494
81 2GQR ADP 0.001181 0.44401 7.59494
82 4K79 GAL A2G 0.02639 0.40104 7.72727
83 3X01 AMP 0.0007003 0.48493 7.77385
84 1TQP ATP 0.0001397 0.45174 7.80142
85 3UDZ ADP 0.000002539 0.55065 7.98722
86 4AXD ANP 0.000001312 0.44985 7.98722
87 5I35 ANP 0.0000042 0.55452 8.12721
88 3PN1 IVH 0.004372 0.44112 8.12721
89 1S9D AFB 0.01736 0.40202 8.37438
90 4R78 AMP 0.0001639 0.50688 8.48057
91 4U98 ACP 0.002285 0.43107 8.48057
92 4Q5H ANP 0.00005207 0.49945 8.62069
93 3TII ANP 0.005242 0.42733 8.68421
94 1ZTH ADP 0.000005019 0.57363 8.91473
95 1ZP9 ATP 0.00001469 0.53661 8.91473
96 5LE1 6UW 0.007429 0.43257 9.02256
97 1VKF CIT 0.01709 0.40623 9.04255
98 3WVR AMP 0.000277 0.47772 9.26518
99 3HAV ATP 0.00009877 0.52867 9.54064
100 5VZ0 ADP 0.0004237 0.43444 9.54064
101 4OYA 1VE 0.00878 0.43421 9.58466
102 1OBD ATP 0.008954 0.41187 9.80392
103 3E7S AT2 0.01628 0.41342 9.90415
104 2CFM AMP 0.007679 0.41927 10.2473
105 1YFS ALA 0.02855 0.40185 10.2473
106 4XMF HSM 0.0001212 0.53952 10.3261
107 1GSA ADP 0.0002083 0.45135 10.5431
108 2BKK ADP 0.001651 0.44666 11.2426
109 2VPQ ANP 0.0001982 0.4507 11.5016
110 4AZT LY2 0.006531 0.42269 11.6608
111 5LXT ACP 0.002705 0.40656 11.8881
112 4OCV ANP 0.0002911 0.46172 12.7796
113 5K2M ADP 0.0006761 0.44758 13.2075
114 3I0O ADP 0.000759 0.46803 13.4185
115 4XYM A12 0.001898 0.41849 13.4783
116 1E4E ADP 0.0007643 0.44361 13.7809
117 2QX0 PH2 0.001679 0.46635 14.4654
118 2W5P CL8 0.01267 0.42573 14.7651
119 2CDO GAL AAL GAL AAL GAL AAL 0.01548 0.41999 15
120 5CKW ANP 0.0003985 0.42275 15.016
121 3VOT ADP 0.0004684 0.47819 15.5477
122 1FWV SGA MAG FUC 0.0322 0.40095 17.1642
123 5TDF ADP 0.001132 0.43224 17.6678
124 5GZ9 ANP 0.00000001831 0.64111 18.3607
125 3TA2 AKG 0.004771 0.41283 20.339
126 4WW7 AMP 0.0002091 0.46543 21.0728
127 5MY8 RXZ 0.0000174 0.51812 21.7252
128 4KBA 1QM 0.0002065 0.42552 22.2615
129 4L9I 8PR 0.00008215 0.49625 22.6148
130 4CRL C1I 0.000004392 0.45218 22.6601
131 5VC5 96M 0.000003208 0.55428 23.1834
132 4XH0 ADP 0.00002678 0.55799 24.0283
133 3GC0 AMP 0.000009271 0.55306 24.2812
134 4BTK DTQ 0.00004313 0.50306 25.8786
135 5T8O 76Z 0.00007095 0.48311 26.5018
136 3LQV ADE 0.01199 0.42238 26.9565
137 4OTH DRN 0.0000004057 0.56753 27.5618
138 2WU6 DKI 0.0000003696 0.55874 28.115
139 3TXO 07U 0.000007025 0.5514 29.0735
140 1XJD STU 0.000000856 0.57104 29.393
141 5TA6 79D 0.0000009939 0.50544 29.393
142 2CSN CKI 0.00000007504 0.55807 29.9663
143 1O9U ADZ 0.0000001854 0.69615 30.0319
144 4NM5 ADP 0.000002374 0.52669 30.0319
145 2JLD AG1 0.00000003359 0.52458 30.0319
146 4O1P ANP 0.00000006918 0.62638 30.0353
147 3F7Z 34O 0.000001083 0.5456 30.3514
148 3ZRM ZRM 0.000006646 0.5389 30.3514
149 3VHE 42Q 0.0000911 0.42578 30.3887
150 5LI1 ANP 0.000000009429 0.6503 30.6709
151 5LI9 ACP 0.0000001082 0.60982 30.6709
152 4DC2 ADE 0.000009339 0.58337 30.6709
153 5X8I SQZ 0.0000008402 0.57854 30.6709
154 5AWM ANP 0.0000009949 0.60767 30.9904
155 2F2U M77 0.00008773 0.51343 30.9904
156 5EKO N17 0.0001779 0.47051 30.9904
157 4NST AF3 0.00000005294 0.66078 31.3099
158 4NST ADP 0.00000006267 0.62828 31.3099
159 4IDT T28 0.000006041 0.5474 31.3099
160 3E7O 35F 0.000109 0.41707 31.3099
161 5EFQ ADP 0.00000006467 0.59617 31.6294
162 4UX9 ANP 0.000000006785 0.65306 31.8021
163 1CM8 ANP 0.00000162 0.57319 31.9489
164 3PTG 932 0.0001148 0.51456 32.1555
165 3ALN ANP 0.000000002847 0.669 32.2684
166 5LPZ ADP 0.000000007857 0.66807 32.2684
167 2VZ6 FEF 0.000002485 0.58008 32.2684
168 4WNK 453 0.000003321 0.5577 32.2684
169 4Y85 499 0.000101 0.46083 32.5088
170 2B9J ADP 0.0000003685 0.6022 32.5879
171 2B9F ADP 0.0000002599 0.60102 32.5879
172 2B9I ADP 0.0000006039 0.58486 32.5879
173 2B9H ADP 0.0000007103 0.57454 32.5879
174 1ZY5 ANP 0.000003466 0.55829 32.5879
175 3E8N ATP 0.000000008977 0.47727 32.5879
176 3E8N VRA 0.000000008977 0.47727 32.5879
177 3TTI KBI 0.000000009621 0.57688 32.8622
178 4BHN BH9 0.00001415 0.51272 32.9073
179 5LXC 7AA 0.0000003147 0.55075 33.2155
180 3UIM ANP 0.0000000001235 0.74765 33.2268
181 2VN9 GVD 0.0000008923 0.61938 33.2268
182 1OUK 084 0.000004618 0.61557 33.2268
183 2WEL K88 0.0000165 0.56909 33.2268
184 4QTB 38Z 0.00000001109 0.56528 33.2268
185 4H3P ANP 0.000000003008 0.68647 33.5463
186 4H3Q ANP 0.000000001016 0.65947 33.5463
187 5BVE 4VG 0.0000004238 0.63844 33.5463
188 4IZY 1J2 0.00000008075 0.60758 33.5463
189 4LOO SB4 0.00002755 0.51165 33.5463
190 5N87 N66 0.00002424 0.52803 33.5689
191 5LPB ADP 0.00000003064 0.56601 33.7838
192 1U5R ATP 0.0000004253 0.59939 33.9223
193 3HMO STU 0.000003214 0.55976 33.9223
194 4D2S DYK 0.000308 0.4287 34.1549
195 5BYZ 4WE 0.00002884 0.51811 34.1853
196 3GNI ATP 0.00000005388 0.61501 34.2756
197 1PHK ATP 0.00000002693 0.6359 34.5638
198 4AU8 Z3R 0.00006861 0.51861 35.1351
199 4WB6 ATP 0.000000006813 0.66829 35.1438
200 3FHI ANP 0.000000008272 0.59284 35.1438
201 2GU8 796 0.000005435 0.58019 35.1438
202 5UKL SIX 0.00002145 0.51824 35.1438
203 3PVW QRX 0.000005409 0.48952 35.1438
204 1UNH IXM 0.000004285 0.5689 35.274
205 3O0G 3O0 0.000005904 0.54785 35.274
206 4FG8 ATP 0.000001015 0.5611 35.3357
207 2F57 23D 0.000004707 0.55942 35.3357
208 5HQ0 LZ9 0.00000006923 0.61041 35.4305
209 4WB7 ATP 0.00000007457 0.49654 35.4633
210 4I6H 1C8 0.000001797 0.56397 35.7143
211 5C03 AGS 0.000000345 0.56534 36.0424
212 3GC8 B45 0.000003425 0.52907 36.3958
213 4BKJ STI 0.0001567 0.47684 36.3958
214 4YLL 4E3 0.0000001284 0.60493 36.7412
215 3HZT J60 0.00005163 0.52459 36.7491
216 3SXF BK5 0.000001395 0.46177 36.7491
217 2QCS ANP 0.000000005671 0.59737 37.0607
218 1RE8 BD2 0.000002924 0.58295 37.0607
219 3IDB ANP 0.000001336 0.53724 37.0607
220 3SLS ANP 0.0000000002336 0.69873 37.1025
221 4AUA 4AU 0.00000896 0.50192 37.1025
222 5UOX 8GY 0.00003023 0.49126 37.2694
223 4WOV 3SM 0.000005803 0.56267 37.4558
224 1V0O INR 0.000002222 0.55315 37.8472
225 2V7O DRN 0.000001871 0.60341 38.1625
226 4K33 ACP 0.0000005659 0.5788 38.1625
227 2Y6O 1N1 0.000006411 0.5167 38.1625
228 1JPA ANP 0.0000001394 0.64001 38.5159
229 4FL3 ANP 0.000000001988 0.66004 38.8693
230 5UR1 YY9 0.00001105 0.55226 38.8693
231 2X2M X2M 0.00002547 0.49384 38.8693
232 4P5Z Q7M 0.00000291 0.57272 39.2226
233 3KRL KRL 0.00007327 0.47422 39.2226
234 4ASE AV9 0.00006965 0.43834 39.2226
235 3GQI ACP 0.000001384 0.56898 39.2971
236 5MJA 7O3 0.00001134 0.48844 39.3443
237 2PVF ACP 0.000001315 0.57727 39.576
238 3RI1 3RH 0.00003803 0.46228 39.576
239 2XVD AS6 0.000003199 0.48222 40.0662
240 3IGO ANP 0.0000001008 0.59101 40.2827
241 5DBX ANP 0.00000002122 0.58199 40.2827
242 2WEI VGG 0.000004249 0.56148 40.2827
243 4QMN DB8 0.000001056 0.45702 40.3226
244 5EOB 5QQ 0.000000234 0.64343 40.636
245 5USZ SKE 0.0000002029 0.53392 40.636
246 3C1X CKK 0.00002581 0.49217 40.636
247 2OO8 RAJ 0.002085 0.41451 40.636
248 4AT3 LTI 0.00005581 0.43529 41.1371
249 4BCQ TJF 0.00001156 0.55608 41.196
250 4BCM T7Z 0.0000008179 0.49596 41.196
251 3LXN MI1 0.00000009455 0.60468 41.2141
252 2BPM 529 0.0000006253 0.42579 41.2141
253 4CFU 2WC 0.0000002421 0.61892 41.2541
254 2XMY CDK 0.0000000455 0.68831 41.2752
255 4BCN T9N 0.000001398 0.59189 41.3333
256 4Y93 746 0.000001692 0.5155 41.3428
257 5HES 032 0.00009702 0.47962 41.3681
258 3H9R TAK 0.00002336 0.54893 41.5335
259 1VJY 460 0.00000001099 0.67175 41.5842
260 4E93 GUI 0.0000004232 0.48927 41.6961
261 3PP0 03Q 0.00001007 0.47799 41.6961
262 5JGA 6KC 0.00003095 0.43556 41.6961
263 5HX8 66P 0.0000001087 0.54935 41.7219
264 5LMK 6ZK 0.000001806 0.52038 41.7508
265 3LXK MI1 0.000002183 0.49693 41.853
266 5JFS 6K0 0.00000141 0.5902 42.2078
267 4YMJ 4EJ 0.00000012 0.6825 42.4342
268 5JKG 6LF 0.0004785 0.47239 42.492
269 2ZV2 609 0.00002112 0.5434 42.6175
270 5HCY 60D 0.000001321 0.59606 42.7562
271 2QLU ADE 0.00003563 0.53888 42.8115
272 4EWH T77 0.00001212 0.46755 43.2727
273 3EKK GS2 0.000002021 0.45077 43.3225
274 4GJ3 0XP 0.000003069 0.46625 43.3775
275 3PLS ANP 0.0000000002344 0.74642 43.4629
276 4FF8 14S 0.0006364 0.40646 43.4629
277 2A19 ANP 0.0000002091 0.64049 43.662
278 3KRR DQX 0.0000006837 0.63069 43.7288
279 3BU5 ATP 0.000001853 0.56338 43.7908
280 5CEO 50D 0.000002168 0.53308 43.8163
281 4E1Z 0MX 0.000006798 0.50959 43.9863
282 5NKB 8ZT 0.00002037 0.40151 44.1696
283 3NW7 LGV 0.0001217 0.50801 44.523
284 3KMW ATP 0.000003803 0.55646 44.6494
285 1BYG STU 0.0000002769 0.61622 44.964
286 3G5D 1N1 0.00002734 0.54705 45.2297
287 5TO8 7FM 0.000007911 0.55459 45.3901
288 1K3A ACP 0.0000003824 0.61851 45.485
289 3SRV S19 0.0000005281 0.59515 45.4874
290 5U6C 7YS 0.00000003867 0.60783 45.583
291 4YZC STU 0.0000009006 0.59408 45.583
292 2H8H H8H 0.00000101 0.57502 45.583
293 1Y57 MPZ 0.000002898 0.52364 45.583
294 1U59 STU 0.00003251 0.50848 45.583
295 5H2U 1N1 0.00000551 0.54249 45.6929
296 5DA3 58V 0.0000001717 0.64464 46.0377
297 4F4P 0SB 0.00006426 0.53242 46.1538
298 3SXS PP2 0.00001155 0.51644 46.2687
299 5FBN 5WF 0.000002937 0.56751 46.4945
300 2OFV 242 0.000004626 0.44114 46.5704
301 1OPK P16 0.0001855 0.40761 46.6431
302 4CLI 5P8 0.000009104 0.55749 46.9965
303 3VRY B43 0.000006349 0.49015 47.3498
304 4CSV STI 0.0001567 0.45254 48.7273
305 4XLI 1N1 0.0001035 0.49173 48.8806
306 2HK5 1BM 0.00001703 0.50932 49.2593
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