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Receptor
PDB id Resolution Class Description Source Keywords
4LX0 2.19 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF MYO5B GLOBULAR TAIL DOMAIN IN COMPLEX W RAB11A HOMO SAPIENS DIL PROTEIN TRANSPORT-CONTRACTILE PROTEIN COMPLEX
Ref.: STRUCTURAL BASIS OF MYOSIN V RAB GTPASE-DEPENDENT C RECOGNITION. PROC.NATL.ACAD.SCI.USA V. 110 20443 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BEF GDP C:202;
A:202;
Valid;
Valid;
none;
none;
submit data n/a n/a n/a n/a
MG A:201;
C:201;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
GOL A:204;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LX0 2.19 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF MYO5B GLOBULAR TAIL DOMAIN IN COMPLEX W RAB11A HOMO SAPIENS DIL PROTEIN TRANSPORT-CONTRACTILE PROTEIN COMPLEX
Ref.: STRUCTURAL BASIS OF MYOSIN V RAB GTPASE-DEPENDENT C RECOGNITION. PROC.NATL.ACAD.SCI.USA V. 110 20443 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4LX0 - BEF GDP n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5JCZ - GDP BEF n/a n/a
2 4LX0 - BEF GDP n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5JCZ - GDP BEF n/a n/a
2 4LX0 - BEF GDP n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BEF GDP; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LX0; Ligand: BEF GDP; Similar sites found with APoc: 513
This union binding pocket(no: 1) in the query (biounit: 4lx0.bio2) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 1M0S CIT 1.36986
2 5M04 GDP 1.40515
3 3KC1 2T6 2.07715
4 2BVN GNP 2.25989
5 1D8T GDP 2.25989
6 1VKJ A3P 2.25989
7 4R43 GDP 2.25989
8 2GKS ADP 2.82486
9 2GDJ ANP 2.82486
10 1Z6T ADP 2.82486
11 1NJF AGS 2.82486
12 1NJF ADP 2.82486
13 4FRZ ADP 2.82486
14 3FYH ADP 2.82486
15 1ION ADP 3.29218
16 3FSY SCA 3.31325
17 1U0J ADP 3.38983
18 2FSH ANP 3.38983
19 2ZPA ADP 3.38983
20 2Q2Y ADP 3.38983
21 2Q2Y MKR 3.38983
22 1OS1 PYR 3.38983
23 3WV6 GAL GLC 3.38983
24 4NE2 ADP 3.38983
25 4NE2 SH2 3.38983
26 1OS1 ATP 3.38983
27 5LB3 ADP 3.51288
28 1APZ ASP 3.5461
29 4NU0 AP5 3.68664
30 2C78 GNP 3.9548
31 2C77 GNP 3.9548
32 2WHX ADP 3.9548
33 3TBK ANP 3.9548
34 1X6V ADP 3.9548
35 4PVR ASP 3.9548
36 1IN4 ADP 3.9548
37 1O8B ABF 3.9548
38 2FAH GDP 3.98126
39 2JLR ANP 3.98126
40 3BER AMP 4.01606
41 4Q1A UDP 4.28571
42 4Q1A 2XZ 4.28571
43 1BG2 ADP 4.30769
44 1V8K ANP 4.39024
45 3IIJ ADP 4.44444
46 4IHQ ADP 4.44965
47 1XP8 AGS 4.51977
48 4ZNL BEF ADP 4.51977
49 1IWE IMP 4.51977
50 2BEK ATP 4.51977
51 2RGX AP5 4.51977
52 1ZIN AP5 4.51977
53 3P4X ADP 4.51977
54 1P9B GDP 4.51977
55 1P9B HDA 4.51977
56 5X40 ACP 4.51977
57 1LK7 DER 4.51977
58 4GOX A3P 4.51977
59 5ZBR ANP 4.53333
60 4LPS GDP 4.54545
61 6AIC AMP 4.6729
62 1G7S GDP 4.68384
63 5WRI A3P 4.6875
64 3H86 AP5 4.6875
65 1SVM ATP 4.77454
66 5WRJ A3P 4.9505
67 1CBK ROI 5
68 6HKE MLT 5.03145
69 6HKE LMR 5.03145
70 4BFW ZVW 5.03145
71 5NLD LBT 5.03597
72 1JJ7 ADP 5.08475
73 1YRB GDP 5.08475
74 5YT0 GDP 5.08475
75 5FG3 GDP 5.08475
76 4KBF AMP 5.08475
77 3IUY AMP 5.08475
78 1W5T ANP 5.08475
79 6B8B ADP 5.08475
80 4PJ3 ANP 5.08475
81 1W5T ADP 5.08475
82 4MKG AP5 5.08475
83 2HXW FLC 5.08475
84 3BFV ADP 5.08475
85 4U60 SIA GAL NGA 5.08475
86 4AG5 ADP 5.08475
87 3FJG 3PG 5.08475
88 3KIH GDL 5.15464
89 1V3S ATP 5.17241
90 6DEF GCP 5.37084
91 1D2N ANP 5.51471
92 3DC4 ADP 5.52326
93 5ZB0 ADP 5.55556
94 5ZB0 TYD 5.55556
95 1SVI GDP 5.64103
96 5I0H ADP BEF 5.64972
97 1B0U ATP 5.64972
98 2OG2 MLI 5.64972
99 3B5J 12D 5.64972
100 4LC1 GDP 5.64972
101 5L3R GCP 5.64972
102 1LVK MNT BEF 5.64972
103 2GK6 ADP 5.64972
104 1FNN ADP 5.64972
105 1NY5 ADP 5.64972
106 5L3V GDP 5.64972
107 5Z69 AGS 5.64972
108 5NM7 GLY 5.64972
109 1F9V ADP 5.64972
110 3AB4 THR 5.64972
111 2NCD ADP 5.64972
112 3QXC ATP 5.64972
113 1CR1 TTP 5.64972
114 3KAL HGS 5.64972
115 5EXT ADP 5.64972
116 1T5C ADP 5.64972
117 2O0J ADP 5.71429
118 2F5X ASP 5.76923
119 4WOP CTP 5.77778
120 1ONI BEZ 5.7971
121 3DKP ADP 6.12245
122 4RD0 GDP 6.21469
123 3CX8 GSP 6.21469
124 3NHB ADP 6.21469
125 1JI0 ATP 6.21469
126 5ZXD ATP 6.21469
127 3TK1 GDP 6.21469
128 3ZS9 ADP ALF 6.21469
129 4R98 GNH 6.21469
130 2WOJ ADP ALF 6.21469
131 2CHG ANP 6.21469
132 3FWY ADP 6.21469
133 1IHU ADP 6.21469
134 1IHU AF3 6.21469
135 3VM7 GLC 6.21469
136 5E5U MLI 6.21469
137 4QRH 0O2 6.21469
138 1R6B ADP 6.21469
139 2WW4 ADP 6.21469
140 5XQL C2E 6.21469
141 5TCI MLI 6.21469
142 2I4I AMP 6.21469
143 1OXV ANP 6.23229
144 6AR9 3L4 6.25
145 2ZFI ADP 6.28415
146 1KO8 6PG 6.28571
147 4IDN GNP 6.32318
148 1OYY AGS 6.32318
149 4O48 ASP 6.3253
150 1JS8 MAN MAN BMA 6.34518
151 4QM7 GTP 6.43275
152 3COB ADP 6.50407
153 3B9Q MLI 6.62252
154 3H4S ADP 6.66667
155 5H4S RAM 6.69014
156 3WXM GTP 6.71141
157 1JPA ANP 6.73077
158 4NCN GTP 6.77966
159 2XTZ GSP 6.77966
160 1CS4 GSP 6.77966
161 1TAD GDP 6.77966
162 1TAD ALF 6.77966
163 1LVG ADP 6.77966
164 2RCN GDP 6.77966
165 1FQK GDP 6.77966
166 1G6O ADP 6.77966
167 4QOS ADP 6.77966
168 4XVU ATP 6.77966
169 5AK0 8V1 6.77966
170 2OFW ADX 6.77966
171 3KJI ADP 6.77966
172 2PEZ DAT 6.77966
173 2PEZ GGZ 6.77966
174 2QEN ADP 6.77966
175 2X7I CIT 6.77966
176 1FQK ALF 6.77966
177 1GOJ ADP 6.77966
178 3QKT ANP 6.77966
179 1NST A3P 6.77966
180 1G3Q ADP 6.77966
181 4HSE ADP 6.77966
182 3HU3 AGS 6.77966
183 5HR5 ADP 6.77966
184 1AQU A3P 6.77966
185 4YMU ATP 6.77966
186 4MKF AP5 6.91244
187 1P77 ATR 6.98529
188 3BOS CDP 7.02479
189 1H65 GDP 7.03704
190 1IZC PYR 7.07965
191 4TL6 ANP 7.11462
192 1FQJ ALF 7.14286
193 1FQJ GDP 7.14286
194 1FIW PBZ 7.24138
195 1RRC ADP 7.30897
196 1G6H ADP 7.34463
197 5YV5 ADP 7.34463
198 1YQT ADP 7.34463
199 4P4T GDP 7.34463
200 1XMV ADP 7.34463
201 4FCW ADP 7.34463
202 4LJ9 ACP 7.34463
203 3DEF GDP 7.34463
204 4YS0 ADP 7.34463
205 2VVG ADP 7.34463
206 1AKY AP5 7.34463
207 1K6M AGS 7.34463
208 1PQ7 ARG 7.34463
209 4TTQ ATP 7.44186
210 4DCT GDP 7.49415
211 1FNZ A2G 7.59494
212 1XX6 ADP 7.8534
213 4NON GDP 7.9096
214 1PUJ GNP 7.9096
215 1QF5 GDP 7.9096
216 1QF5 RPL 7.9096
217 2IYL GDP 7.9096
218 5YLF BGC 7.9096
219 3ITJ CIT 7.9096
220 3FVQ ATP 7.9096
221 6B4K ANP 7.9096
222 2ZJ5 ADP 7.9096
223 3CV2 OXL 7.9096
224 1G41 ADP 7.9096
225 1NHX FTB 7.9096
226 1NHX PEP 7.9096
227 5BN3 ADP 7.9096
228 2IXE ATP 7.9096
229 1G8S MET 7.9096
230 1XKV ATP 7.9096
231 1P7T PYR 7.9096
232 1D8C GLV 7.9096
233 2BO4 FLC 7.9096
234 1LOJ URI 8.04598
235 1LOJ U 8.04598
236 1L2T ATP 8.08511
237 4XTR ATP 8.10811
238 4XTR ADP 8.10811
239 5GVR LMR 8.11966
240 1SQL GUN 8.21918
241 3BP1 GUN 8.27586
242 1ZUI SKM 8.33333
243 6AYU F6P 8.35735
244 1NBU PH2 8.40336
245 2W58 ADP 8.41584
246 4IEE AGS 8.43091
247 5U32 GDP 8.47458
248 1F5N GNP 8.47458
249 2B8W ALF 5GP 8.47458
250 3DZD ADP 8.47458
251 2D7D ADP 8.47458
252 4A4Z ANP 8.47458
253 1B7T ADP 8.47458
254 5MEX PAP 8.47458
255 2Y65 ADP 8.47458
256 1W7J ADP BEF 8.60927
257 4OI4 ATP 8.69565
258 1UKG MMA 8.73016
259 1Q8Q MAN MMA 8.73016
260 1Q8S MAN MMA 8.73016
261 5UIV ADP 8.81057
262 5FII PHE 8.82353
263 2HF9 GSP 8.84956
264 1K4M CIT 8.92019
265 1DAK ADP 8.92857
266 1DAK DPU 8.92857
267 3AB3 GDP 8.94309
268 5TSH ADP 9.03955
269 5TSH ANP 9.03955
270 1RJ9 GCP 9.03955
271 3MD0 GDP 9.03955
272 3ZFD ANP 9.03955
273 2IS6 ADP 9.03955
274 5Y6N ADP 9.03955
275 2VB6 ADP BEF 9.03955
276 4PFO ADP 9.03955
277 2C9O ADP 9.03955
278 4ZDJ UTP 9.03955
279 5I34 GDP 9.03955
280 1SVK ALF GDP 9.06516
281 4H1V GNP 9.21409
282 2ODE ALF GDP 9.21986
283 1KK8 BEF ADP 9.35252
284 5N69 ADP 9.54774
285 2DPY ADP 9.60452
286 2BIF ANP 9.60452
287 2BIF SIN 9.60452
288 1FP6 ADP 9.60452
289 4X8O AP5 9.60452
290 4IOK XPO 9.60452
291 4IOK ADP 9.60452
292 4B47 GDP 9.64187
293 4B5W PYR 9.76562
294 2FH5 GTP 9.81308
295 6CRK GDP 9.85915
296 1GP2 GDP 9.85915
297 4R2I ANP 10
298 1Y3A GDP 10.0304
299 5BQ5 ADP BEF 10.0529
300 1SQ5 ADP 10.0649
301 2WJG GDP 10.1064
302 5L3W GDP 10.1307
303 5L3S GNP 10.1351
304 2OM2 GDP 10.1538
305 1BH2 GSP 10.1587
306 4ZG4 VO4 ADP 10.1695
307 3VX3 ADP 10.1695
308 2OFE NAG 10.5634
309 4Z2S NDG 10.5634
310 4Z2S NAG 10.5634
311 2OFD NGA 10.5634
312 3A1S GDP 10.7345
313 1W0J ADP 10.7345
314 2XAU ADP 10.7345
315 1W0J ADP BEF 10.7345
316 2CE7 ADP 10.7345
317 1TQ4 GDP 11.138
318 1Y2W NAG 11.2676
319 6AU6 GDP 11.2994
320 3ZQ6 ADP ALF 11.2994
321 1VHT BA3 11.2994
322 1YTM ATP 11.2994
323 2GWH A3P 11.2994
324 1BO4 COA 11.3095
325 4PTN PYR 11.3703
326 2WJH GDP 11.4458
327 2WJH FLC 11.4458
328 3BFX A3P 11.4865
329 5XKT GNP 11.5
330 2D2F ADP 11.6
331 1P6O HPY 11.8012
332 3R7F CP 11.8644
333 2XCU C5P 11.8644
334 3QF7 ANP 12
335 1GOT GDP 12.3288
336 1ZHS NAG NAG BMA MAN MAN 12.3894
337 1M2O GNP 12.4294
338 2QTV GNP 12.4294
339 3EC1 GDP 12.4294
340 5CK5 GDP 12.4294
341 2PL3 ADP 12.4294
342 5MZN ADP 12.4294
343 3FB4 AP5 12.5
344 1D2E GDP 12.9944
345 2CDN ADP 12.9944
346 2WIC GNP 12.9944
347 1DCP HBI 13.4615
348 1P4V GLY 13.5593
349 4GBM A3P 13.5593
350 2ZR9 DTP 14.1243
351 1M7G ADX 14.1243
352 1M7G ADP 14.1243
353 1M7G AV2 14.1243
354 3UG4 AHR 14.1243
355 1QHG ATP 14.6893
356 1G7C 5GP 15.2542
357 1NRJ GTP 15.2542
358 1E2K TMC 15.2542
359 2XT3 ADP 15.2542
360 4PU6 ASP 15.2672
361 1DAR GDP 15.8192
362 3ZIA ADP 15.873
363 3ZIA ATP 15.873
364 1QHH ATP 15.9763
365 4ZJS 4P0 16.087
366 2HCJ GDP 16.2162
367 4PX9 ADP 16.3842
368 4HI0 GDP 16.3842
369 3RC3 ANP 16.3842
370 1GXU 2HP 16.4835
371 4CVN ADP 16.7539
372 2GJ8 ALF GDP 16.8605
373 6G14 G4P 16.9492
374 3B7G ANP 16.9492
375 1OFH ADP 16.9492
376 2QZ4 ADP 16.9492
377 2KIN ADP 17
378 1SKQ GDP 17.5141
379 2V7Q ADP 18
380 2V7Q ATP 18
381 2CK3 ADP 18
382 2CK3 ANP 18
383 3PQC GDP 18.0791
384 1S3G AP5 18.4332
385 5HCN GCP 18.6441
386 4KFU ACP 18.8679
387 1F2U ATP 18.9189
388 2DT9 THR 19.1617
389 4BQS K2Q 19.3182
390 4BQS ADP 19.3182
391 1P72 ADP 19.774
392 1UJ2 C5P 20.339
393 1UJ2 ADP 20.339
394 1UPT GTP 20.4678
395 3E70 GDP 20.904
396 2AWN ADP 20.904
397 2VWT PYR 20.9738
398 5TDC NMM ILE PHE SER 21.0526
399 1ZJ6 G3D 21.4689
400 1F6B GDP 21.4689
401 3UIE ANP 22
402 1KK1 GNP 22.0339
403 3A4M ADP 22.0339
404 4WZ6 ATP 22.5989
405 2J5V PCA 23.1638
406 4WZA ACP 23.7288
407 4WZA ADP 23.7288
408 3RLF ANP 23.7288
409 4U00 ADP 25.4237
410 1JJV ATP 25.4237
411 4D81 ADP 25.4237
412 4BAS GNP 26.1307
413 4M9Q GNP 28.2486
414 1WF3 GNP 28.8136
415 5KUT GDP 29.9435
416 6C90 ADP 30.7692
417 1KSH GDP 31.0734
418 1ZD9 GDP 31.0734
419 2XTN GTP 31.0734
420 2A5F GTP 31.4286
421 1MR3 G3D 31.6384
422 1FZQ GDP 31.6384
423 1YZG GDP 32.2034
424 1J2J GTP 32.5301
425 1O3Y GTP 32.5301
426 1RE0 GDP 33.5366
427 1S9D GDP 33.5366
428 4V0K GDP 33.7278
429 5KDO GDP 33.7838
430 1XEX ATP 34.3023
431 5UPK GNP 34.4633
432 1NF3 GNP 34.4633
433 1GRN GDP 35.0282
434 1GRN AF3 35.0282
435 4ITR GDP 35.0282
436 1A4R GDP 35.0282
437 1A4R GNH 35.0282
438 2NGR GDP 35.0282
439 2NGR AF3 35.0282
440 3W5J GDP 35.0282
441 4DID GDP 35.2332
442 3KTA AP5 35.2601
443 5KSP GDP 35.5932
444 5KSZ GCP 35.5932
445 3T12 GDP ALF 36.1582
446 3T1O GDP 36.1582
447 2QN6 GDP 38.8889
448 2ZEJ GDP 40.113
449 6CS8 F9Y 41.2429
450 1R4A GNP 42.4242
451 3Q85 GNP 43.1953
452 1MKY GDP 44.0678
453 2W2X GSP 45.1977
454 1DS6 GDP 45.1977
455 1E96 GTP 45.7627
456 6BSX E7S 45.7627
457 6BSX GDP 45.7627
458 3REF GDP 45.7627
459 3T5G GDP 45.7627
460 4HAT GNP 46.3277
461 1IBR GNP 46.3277
462 3M1I GTP 46.3277
463 5BXQ GDP 46.3277
464 3GJ7 GDP 46.3277
465 3GJ5 GDP 46.3277
466 1KMQ GNP 46.3277
467 2FJU GSP 46.3277
468 3GJ8 GDP 46.3277
469 3CH5 GDP 46.3277
470 3GJ4 GDP 46.3277
471 1I4D GDP 46.3277
472 1HE1 GDP 46.5909
473 1HE1 AF3 46.5909
474 3SBD GNP 46.8927
475 1MH1 GNP 46.8927
476 2WKQ GTP 46.8927
477 1TX4 ALF GDP 46.8927
478 1G4U AF3 46.8927
479 5HPY GDP 46.8927
480 1OW3 GDP 46.8927
481 5IRC GDP 46.8927
482 1G4U GDP 46.8927
483 1WA5 GTP 47.1591
484 1CXZ GSP 47.4576
485 3GJ3 GDP 47.4576
486 3GJ0 GDP 47.4576
487 4D0N GDP 47.4576
488 1RYH GNP 47.4576
489 5DIF GNP 48.0226
490 5UWJ GNP 48.0226
491 5UWW GNP 48.0226
492 5UWP GNP 48.0226
493 5UWQ GNP 48.0226
494 5UWI GNP 48.0226
495 6CIT GNP 48.0226
496 5UWR GNP 48.0226
497 5UWO GNP 48.0226
498 5UWT GNP 48.0226
499 5UWS GNP 48.0226
500 5UWU GNP 48.0226
501 5DHF GNP 48.0226
502 5UWH GNP 48.0226
503 2GCO GNP 48.0226
504 5DI9 GNP 48.0226
505 1M7B GTP 48.0226
506 2GCN GDP 48.0226
507 2CJW GDP 48.5876
508 2J0V GDP 48.5876
509 5UQW GDP 48.6772
510 1GWN GTP 49.1525
511 2HT6 GDP 49.4253
512 1X1R GDP 49.4382
513 4U5X GNP 49.7175
514 3Q72 GNP 50
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