Receptor
PDB id Resolution Class Description Source Keywords
4LWP 2.35 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF PRMT6-SAH TRYPANOSOMA BRUCEI BRUCEI SAM BINDING DOMAIN ARGININE METHYLATION TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF ARGININE METHYLTRANSFERASE 6 F TRYPANOSOMA BRUCEI PLOS ONE V. 9 87267 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
IOD B:403;
B:402;
B:401;
B:406;
A:404;
A:402;
A:403;
B:404;
B:405;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
126.904 I [I-]
SAH A:401;
B:407;
Valid;
Valid;
none;
none;
Kd = 45 uM
384.411 C14 H20 N6 O5 S c1nc(...
PGE A:405;
Invalid;
none;
submit data
150.173 C6 H14 O4 C(COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LWP 2.35 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF PRMT6-SAH TRYPANOSOMA BRUCEI BRUCEI SAM BINDING DOMAIN ARGININE METHYLATION TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF ARGININE METHYLTRANSFERASE 6 F TRYPANOSOMA BRUCEI PLOS ONE V. 9 87267 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 4LWP Kd = 45 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 4LWP Kd = 45 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 4LWP Kd = 45 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 197
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 SXZ 0.692308 0.916667
6 DSH 0.692308 0.914286
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 ADN 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 AMP 0.529412 0.763158
36 A 0.529412 0.763158
37 5CA 0.525773 0.712644
38 ME8 0.524752 0.8125
39 M2T 0.52439 0.821918
40 6RE 0.523256 0.824324
41 GJV 0.522727 0.813333
42 AAT 0.515789 0.863014
43 LSS 0.515152 0.696629
44 KAA 0.514852 0.727273
45 J7C 0.511364 0.835616
46 A5A 0.510417 0.697674
47 SON 0.505495 0.805195
48 SRP 0.505155 0.805195
49 5AL 0.5 0.779221
50 VMS 0.5 0.681818
51 KH3 0.5 0.866667
52 ADX 0.5 0.694118
53 CA0 0.5 0.769231
54 AMP MG 0.5 0.74359
55 AMO 0.5 0.805195
56 54H 0.5 0.681818
57 AHX 0.49505 0.753086
58 TSB 0.494949 0.689655
59 53H 0.494949 0.674157
60 G5A 0.494737 0.712644
61 A2D 0.494382 0.74359
62 ABM 0.494382 0.74359
63 ZAS 0.494253 0.808219
64 A6D 0.490196 0.759494
65 8QN 0.49 0.779221
66 GEK 0.49 0.956522
67 GAP 0.489583 0.769231
68 A3S 0.48913 0.884058
69 AN2 0.48913 0.734177
70 S4M 0.488889 0.831169
71 SRA 0.488636 0.746835
72 LAD 0.485437 0.810127
73 52H 0.484848 0.674157
74 A12 0.483516 0.759494
75 BA3 0.483516 0.74359
76 AP2 0.483516 0.759494
77 AOC 0.483146 0.842857
78 NEC 0.483146 0.788732
79 Y3J 0.481481 0.768116
80 NVA LMS 0.480392 0.696629
81 VRT 0.479167 0.861111
82 50T 0.478723 0.734177
83 5AS 0.478261 0.655556
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 AP5 0.478261 0.74359
87 A3N 0.477778 0.830986
88 YSA 0.476636 0.712644
89 XAH 0.476636 0.768293
90 0XU 0.473684 0.897059
91 WAQ 0.471154 0.807692
92 NSS 0.470588 0.712644
93 5AD 0.468354 0.791045
94 ADP MG 0.468085 0.734177
95 AU1 0.468085 0.725
96 M33 0.468085 0.734177
97 MAO 0.467391 0.797468
98 TXA 0.466667 0.759494
99 A3G 0.466667 0.871429
100 NB8 0.466667 0.775
101 3AM 0.465909 0.727273
102 DAL AMP 0.465347 0.779221
103 ATP 0.463158 0.74359
104 ADP BEF 0.463158 0.716049
105 A3T 0.463158 0.842857
106 BEF ADP 0.463158 0.716049
107 ACP 0.463158 0.746835
108 7D7 0.4625 0.785714
109 LEU LMS 0.461538 0.677778
110 APC 0.458333 0.759494
111 AQP 0.458333 0.74359
112 APR 0.458333 0.766234
113 PRX 0.458333 0.746835
114 AR6 0.458333 0.766234
115 5FA 0.458333 0.74359
116 IOT 0.456897 0.761905
117 4AD 0.456311 0.794872
118 PAJ 0.456311 0.722892
119 WSA 0.45614 0.72093
120 FA5 0.453704 0.805195
121 YAP 0.453704 0.794872
122 RBY 0.453608 0.782051
123 ADV 0.453608 0.782051
124 ADP PO3 0.453608 0.763158
125 AD9 0.453608 0.725
126 SAP 0.453608 0.728395
127 AGS 0.453608 0.728395
128 PTJ 0.45283 0.731707
129 MHZ 0.452632 0.797468
130 00A 0.451923 0.740741
131 A3P 0.451613 0.74026
132 YLP 0.451327 0.771084
133 7MD 0.45045 0.768293
134 ALF ADP 0.45 0.707317
135 ADP ALF 0.45 0.707317
136 ATP MG 0.44898 0.734177
137 2VA 0.447917 0.819444
138 OOB 0.446602 0.779221
139 ANP 0.444444 0.725
140 ACQ 0.444444 0.746835
141 TAT 0.444444 0.7375
142 P5A 0.443396 0.719101
143 7D5 0.443182 0.708861
144 ARG AMP 0.442478 0.759036
145 A1R 0.442308 0.7625
146 YLC 0.439655 0.790123
147 2AM 0.438202 0.717949
148 DLL 0.438095 0.779221
149 A22 0.436893 0.734177
150 D3Y 0.436893 0.859155
151 TYR AMP 0.436364 0.782051
152 ATF 0.435644 0.716049
153 MYR AMP 0.435185 0.746988
154 SO8 0.434343 0.808219
155 3UK 0.433962 0.769231
156 OAD 0.433962 0.769231
157 TAD 0.433628 0.765432
158 25A 0.432692 0.74359
159 ANP MG 0.431373 0.707317
160 VO4 ADP 0.431373 0.734177
161 ADP VO4 0.431373 0.734177
162 9SN 0.431193 0.731707
163 TYM 0.431034 0.805195
164 PR8 0.429907 0.8
165 ADQ 0.428571 0.746835
166 YLB 0.42735 0.771084
167 3OD 0.425926 0.769231
168 FYA 0.425926 0.779221
169 1ZZ 0.425926 0.746988
170 PPS 0.425743 0.674419
171 NVA 2AD 0.424242 0.808219
172 MAP 0.423077 0.707317
173 A2P 0.421053 0.727273
174 4YB 0.421053 0.735632
175 ADP BMA 0.420561 0.746835
176 5SV 0.419048 0.731707
177 3NZ 0.416667 0.824324
178 YLA 0.416667 0.771084
179 48N 0.413793 0.753086
180 LPA AMP 0.413793 0.768293
181 AYB 0.413223 0.761905
182 QQY 0.413043 0.696203
183 ACK 0.413043 0.710526
184 JB6 0.412844 0.7625
185 BIS 0.412844 0.719512
186 PAP 0.41 0.730769
187 OVE 0.408602 0.7125
188 4UV 0.40708 0.75
189 AMP DBH 0.40708 0.746835
190 3AD 0.406977 0.852941
191 AF3 ADP 3PG 0.40678 0.743902
192 OMR 0.40678 0.738095
193 LAQ 0.405172 0.768293
194 A A 0.40367 0.74359
195 7C5 0.403509 0.789474
196 7MC 0.403361 0.75
197 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LWP; Ligand: SAH; Similar sites found: 256
This union binding pocket(no: 1) in the query (biounit: 4lwp.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3OFK SAH 0.0001895 0.44586 None
2 2BOS GLA GAL GLC 0.02463 0.40105 None
3 5ITV NAI 0.001474 0.44777 1.56863
4 3GEG NAD 0.0003291 0.40484 1.61943
5 5X62 SAH 0.000004047 0.54568 1.63043
6 3M6W SAM 0.0003372 0.46637 1.63043
7 3SSO SAH 0.0002649 0.4472 1.63043
8 4FZV SAM 0.00001815 0.49234 1.67364
9 1M1B SPV 0.01353 0.41472 1.69492
10 2AOT SAH 0.00005416 0.50199 1.71233
11 1JQD SAH 0.0002491 0.40239 1.71233
12 5MPT SAH 0.00006033 0.48881 1.90217
13 1UWK NAD 0.005323 0.43725 1.90217
14 3GWZ SAH 0.003411 0.42541 1.90217
15 3GXO SAH 0.004945 0.41401 1.90217
16 4Q9N NAI 0.01324 0.40443 2.01342
17 2XYQ SAH 0.000369 0.45506 2.06897
18 2DPM SAM 0.0001662 0.44727 2.11268
19 1XCL SAH 0.00003251 0.42031 2.12766
20 4MO2 FDA 0.0005753 0.47427 2.17391
21 4EIP FAD 0.01583 0.41551 2.17391
22 4EIP K2C 0.01583 0.41551 2.17391
23 4ONQ SFG 0.00002669 0.50402 2.2409
24 5E9W SAH 0.00001779 0.48241 2.24359
25 1N2X SAM 0.0004594 0.42691 2.32558
26 2EJU SAH 0.0000003743 0.58354 2.44565
27 4BV6 FAD 0.001129 0.46516 2.44565
28 5BUK FAD 0.002278 0.45382 2.44565
29 3ICT ADP 0.01208 0.4039 2.44565
30 5EOW FAD 0.01115 0.41133 2.46914
31 1P1C SAH 0.0001908 0.43685 2.51256
32 4FC7 COA 0.00319 0.44498 2.52708
33 3A4T SFG 0.000001474 0.52516 2.55474
34 1QH9 LAC 0.02282 0.40152 2.58621
35 5DM1 SAH 0.00000212 0.41757 2.62172
36 5DM1 5D7 0.000002286 0.41236 2.62172
37 1G55 SAH 0.000003996 0.52934 2.62391
38 4D7E FAD 0.0006441 0.47077 2.71739
39 2IZ1 ATR 0.02402 0.4054 2.71739
40 1TPY SAH 0.0002317 0.44236 2.78746
41 3GU3 SAH 0.00008307 0.5122 2.8169
42 2ZE3 AKG 0.01978 0.40878 2.90909
43 5EZ7 FAD 0.009933 0.41887 2.98913
44 1D4D SIN 0.02206 0.40332 2.98913
45 4RDH AMP 0.0005434 0.45707 3.125
46 4RDI ATP 0.0006354 0.44493 3.125
47 5FTW SAH 0.000957 0.42464 3.125
48 4J7U YTZ 0.02099 0.40631 3.125
49 4J7U NAP 0.02099 0.40631 3.125
50 3G89 SAM 0.0000003837 0.60668 3.21285
51 2EFJ SAH 0.00009318 0.48593 3.26087
52 4N49 SAM 0.0002868 0.4463 3.26087
53 5G3U FDA 0.002692 0.44431 3.26087
54 5G3U ITW 0.007924 0.42816 3.26087
55 2CDU ADP 0.008164 0.40066 3.26087
56 3D3W NAP 0.001332 0.45245 3.27869
57 1RJD SAM 0.00007114 0.46683 3.29341
58 1YXM ADE 0.0005746 0.48177 3.30033
59 5THQ NDP 0.004342 0.42516 3.30882
60 3C3Y SAH 0.0008285 0.43413 3.37553
61 3RKR NAP 0.004621 0.42808 3.43511
62 1ZEM NAD 0.0005959 0.40575 3.43511
63 3ZNN FAD 0.007798 0.43719 3.45821
64 3TKA SAM 0.002198 0.4104 3.45821
65 3BGD SAH 0.00001827 0.47504 3.46154
66 3BGD PM6 0.00003327 0.43848 3.46154
67 1Q0S SAH 0.0000753 0.44725 3.4749
68 1TDF FAD 0.009766 0.42555 3.48101
69 3CH6 NAP 0.007175 0.44172 3.4965
70 4UP3 FAD 0.003772 0.43957 3.50318
71 3C6K MTA 0.0000415 0.52577 3.53261
72 3S1S SAH 0.000003306 0.50237 3.53261
73 3NDJ JHZ 0.0002747 0.49939 3.53261
74 5FJN FAD 0.0009469 0.46982 3.53261
75 5FJN BE2 0.001098 0.46982 3.53261
76 5JAQ NAI 0.003967 0.43752 3.53261
77 3C6K SPD 0.00002956 0.40619 3.53261
78 2UYQ SAM 0.0004307 0.49341 3.54839
79 4M73 SAH 0.000002457 0.58245 3.56083
80 4M73 M72 0.00002959 0.40067 3.56083
81 3P9C SAH 0.0001005 0.41077 3.57143
82 4X7Y SAH 0.003859 0.4401 3.64964
83 1RRC ADP 0.01266 0.41839 3.65448
84 1QAN SAH 0.000005146 0.50643 3.68852
85 4RPL FAD 0.0006258 0.49516 3.80435
86 4RPL 3UC 0.0009294 0.48885 3.80435
87 5JCA FAD 0.002526 0.44976 3.80435
88 4OPC FDA 0.01019 0.44967 3.80435
89 5JCA NDP 0.005172 0.4487 3.80435
90 4OBW SAM 0.0006491 0.44453 3.89105
91 5L53 NAP 0.007287 0.40474 4.01235
92 3G2O SAM 0.00002193 0.50768 4.01338
93 4X9M FAD 0.0005311 0.47942 4.06699
94 1Y8Q ATP 0.00005118 0.45054 4.07609
95 2PX8 SAH 0.0006307 0.44507 4.08922
96 1KYZ SAH 0.0001251 0.47522 4.10959
97 1UAY ADN 0.0003051 0.47356 4.13223
98 3LCC SAH 0.00002306 0.51253 4.25532
99 3CBG SAH 0.0003134 0.46283 4.74138
100 1LVL NAD 0.0004983 0.43424 4.80349
101 5MBX SP5 0.001734 0.46738 4.8913
102 5MBX FAD 0.001734 0.46738 4.8913
103 1Q9I TEO 0.002921 0.45795 4.8913
104 4XFR CIT 0.01043 0.41872 4.8913
105 5GWX SAM 0.0002105 0.42218 4.92958
106 5GWX SAR 0.0002105 0.42218 4.92958
107 3MB5 SAM 0.00006477 0.46107 5.09804
108 5JJR SAH 0.0000484 0.49292 5.16304
109 3GCZ SAM 0.0000829 0.48289 5.16304
110 3TKY SAH 0.0001309 0.47671 5.16304
111 5EB4 FAD 0.002714 0.44626 5.16304
112 4YAG NAI 0.01907 0.40829 5.19031
113 1R18 SAH 0.000006154 0.50118 5.28634
114 4QTU SAM 0.000003597 0.53037 5.28846
115 4D42 W0I 0.007643 0.4331 5.31915
116 4D42 NAP 0.007643 0.4331 5.31915
117 2ZIF SAM 0.00001785 0.50079 5.38721
118 3GDH SAH 0.00003413 0.45902 5.39419
119 1V59 NAD 0.0001483 0.49383 5.43478
120 3I53 SAH 0.0001038 0.46372 5.43478
121 3CGD FAD 0.00608 0.45373 5.43478
122 3CGD COA 0.00608 0.45373 5.43478
123 1E1M FAD 0.004023 0.44891 5.43478
124 5U8U FAD 0.01057 0.43535 5.43478
125 5K7U SAM 0.00206 0.42299 5.44413
126 3DXY SAM 0.000008959 0.55112 5.50459
127 2WK1 SAH 0.000918 0.42612 5.67376
128 2R4J 13P 0.0007048 0.48456 5.70652
129 2ZWA SAH 0.00008523 0.46023 5.70652
130 1ZMD NAI 0.0008465 0.40327 5.70652
131 4R6W SAH 0.000001272 0.45399 5.81395
132 2P41 SAH 0.00003936 0.49677 5.90164
133 3PT9 SAH 0.00000434 0.53787 5.97826
134 4DCM SAM 0.000008789 0.53741 5.97826
135 4DMG SAM 0.00009739 0.50241 5.97826
136 1PN0 FAD 0.003727 0.44638 5.97826
137 1PN0 IPH 0.003884 0.44638 5.97826
138 5XVK SAH 0.0002571 0.43803 5.98592
139 3FZG SAM 0.0004004 0.46302 6
140 1Z3C SA8 0.000006747 0.44813 6.04027
141 2WA2 SAM 0.00007455 0.49018 6.15942
142 3QOX SAH 0.0000009491 0.52456 6.25
143 5THY SAH 0.0000963 0.46536 6.25
144 1WG8 SAM 0.0003467 0.46639 6.31579
145 5IL1 SAM 0.003722 0.41196 6.33333
146 1XDS SAM 0.0009517 0.45088 6.41711
147 2BZG SAH 0.00001934 0.51002 6.46552
148 3EVG SAH 0.0000402 0.49638 6.54545
149 1IM8 SAI 0.00000006662 0.5899 6.55738
150 5J60 FAD 0.0003264 0.48931 6.5625
151 1VE3 SAM 0.000007095 0.52871 6.60793
152 1I1N SAH 0.000008214 0.45806 6.63717
153 5E1M PRO PRO LYS ARG ILE ALA 0.00001697 0.54064 6.639
154 5E1M SAH 0.00001697 0.54064 6.639
155 1NV8 SAM 0.000003043 0.46844 6.69014
156 1NV8 MEQ 0.00002083 0.44838 6.69014
157 3K6V CIT 0.02251 0.4047 6.77966
158 5THZ SAH 0.0001379 0.48212 6.79348
159 1QZZ SAM 0.002734 0.42983 6.79348
160 3SZB I1E 0.02204 0.40684 6.79348
161 3O7W SAM 0.00001454 0.53423 6.80272
162 5MW4 5JU 0.00000321 0.58318 6.88623
163 2XOC ADP 0.02692 0.40423 6.89655
164 1G60 SAM 0.0001066 0.46969 6.92308
165 1J0X NAD 0.01531 0.41369 6.92771
166 4IWN GEK 0.0000004683 0.59055 6.9869
167 4REP FAD 0.0009364 0.46678 7.06522
168 5CUQ NSC 0.00009061 0.50427 7.11611
169 1R6D DAU 0.005179 0.44282 7.12166
170 1R6D NAD 0.005375 0.44282 7.12166
171 2PT9 S4M 0.00004316 0.44767 7.16511
172 5T2U NAP 0.01043 0.41152 7.25806
173 3EGI ADP 0.0002013 0.50711 7.28155
174 3W9F I3P 0.02215 0.4184 7.30769
175 1KPG SAH 0.0002004 0.44517 7.31707
176 4A6D SAM 0.0003868 0.44685 7.33696
177 2NXE SAM 0.000003516 0.54179 7.48031
178 5JCM ISD 0.003634 0.45826 7.6087
179 5JCM FAD 0.003522 0.45826 7.6087
180 5JCM NAD 0.003634 0.45826 7.6087
181 4BLW SAH 0.0003881 0.41208 7.61246
182 1KPH SAH 0.0002235 0.44341 7.66551
183 3HVJ 705 0.000005726 0.41903 7.69231
184 1LSS NAD 0.0005039 0.43579 7.85714
185 2PZM UDP 0.003716 0.44282 7.87879
186 4AZW SAM 0.00012 0.46843 7.88043
187 3UCL FAD 0.006926 0.44443 7.88043
188 3VYW SAM 0.0003398 0.44343 8.11688
189 3FUU ADN 0.0000461 0.48452 8.11808
190 3VSE SAH 0.000005111 0.56257 8.15217
191 2HMT NAI 0.001311 0.4138 8.33333
192 4YNU LGC 0.0004747 0.49005 8.42391
193 4YNU FAD 0.0003909 0.49005 8.42391
194 5UAO FAD 0.007496 0.42359 8.42391
195 3DUW SAH 0.00002257 0.49831 8.52018
196 4II2 ATP 0.0007037 0.43035 8.58896
197 4D79 ATP 0.0008184 0.44021 8.69565
198 2A14 SAH 0.0003323 0.43949 8.74525
199 2FK8 SAM 0.0001834 0.45338 8.80503
200 1DL5 SAH 0.000007219 0.46638 8.83281
201 3DMH SAM 0.0000002829 0.5636 8.96739
202 5KOK SAH 0.00001766 0.50244 8.96739
203 3DMH GMP 0.0000003693 0.50227 8.96739
204 4UCI SAM 0.001741 0.42816 8.96739
205 3A25 SAM 0.0000562 0.49014 8.9701
206 4YSX FAD 0.006276 0.4292 8.97436
207 3GRU AMP 0.00005348 0.4584 9.15254
208 2JJQ SAH 0.00002825 0.52099 9.23913
209 2VT3 ATP 0.01164 0.40465 9.30233
210 5L95 AMP 0.0006882 0.44558 9.319
211 5MGZ SAH 0.0001882 0.4599 9.32203
212 3TLJ SAH 0.00002939 0.46883 9.51087
213 2XVM SAH 0.00002757 0.52147 9.54774
214 5M58 SAH 0.0002379 0.4655 9.56522
215 1NW5 SAM 0.00004736 0.48423 9.71787
216 3H8V ATP 0.001708 0.42649 10.274
217 3VC1 SAH 0.000154 0.50456 10.5769
218 3JWH SAH 0.00001471 0.54099 10.5991
219 3FRH SAH 0.0004252 0.46063 11.0672
220 1WY7 SAH 0.000002247 0.519 11.1111
221 1JG3 ADN 0.0001772 0.46874 11.4894
222 2YX1 SFG 0.0000004566 0.55211 11.6071
223 5HJM MTA 0.000001273 0.54858 11.9318
224 2PWY SAH 0.000004869 0.4971 12.4031
225 4POO SAM 0.0001421 0.43872 12.5
226 2EG5 SAH 0.00006159 0.50545 12.7717
227 1ZQ9 SAM 0.0009471 0.43749 12.9825
228 1EJ0 SAM 0.00002536 0.50497 13.8889
229 1L1E SAH 0.0001112 0.4614 13.9373
230 4K90 MLA 0.02257 0.40183 14.1304
231 3EGV SAH 0.000002004 0.55906 14.2857
232 3WV8 ATP 0.0008866 0.44082 14.6789
233 1U2Z SAH 0.0000002161 0.54619 16.3043
234 2PXX SAH 0.0001349 0.46574 16.7442
235 2VDV SAM 0.000005856 0.55236 17.0732
236 3A27 SAM 0.00001171 0.51936 19.1176
237 4X60 SFG 0.0000000614 0.45896 20.9239
238 4X60 3XV 0.00000006679 0.4531 20.9239
239 4C4A SAH 0.0000000001175 0.71457 21.7391
240 3Q87 SAM 0.00001808 0.47786 24.8
241 4M37 SAH 0.00000000202 0.66509 25.656
242 4XUC 43G 0.000004536 0.56691 25.6881
243 4XUC SAM 0.000004536 0.56691 25.6881
244 5E8J SAH 0.00001641 0.53182 27.2727
245 4GQB 0XU 0.000000003537 0.60141 31.8182
246 3X0D SAH 0.0000000001068 0.71705 32.8804
247 4M38 SAH 0.000000001024 0.66133 33.3333
248 5FA5 MTA 0.0000002148 0.6097 35
249 5K8V 6RE 0.00000000003125 0.45784 44.3213
250 4Y2H SAH 0.000000000006216 0.84807 44.8864
251 4Y2H 49K 0.00000000001983 0.82459 44.8864
252 5DX1 SFG 0.000000000001234 0.84298 45.8453
253 5DX0 SFG 0.000000000002023 0.83345 45.8453
254 5DWQ SFG 0.000000000002369 0.82685 45.8453
255 5DX8 SFG 0.000000000001679 0.73472 45.8453
256 5DXA SFG 0.000000000002508 0.72846 45.8453
Pocket No.: 2; Query (leader) PDB : 4LWP; Ligand: SAH; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4lwp.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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