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Receptor
PDB id Resolution Class Description Source Keywords
4LHW 1.55 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF RAB8 IN ITS ACTIVE GPPNHP-BOUND FORM HOMO SAPIENS SMALL GTPASE PROTEIN TRANSPORT
Ref.: INTERMEDIATES IN THE GUANINE NUCLEOTIDE EXCHANGE RE RAB8 PROTEIN CATALYZED BY GUANINE NUCLEOTIDE EXCHAN FACTORS RABIN8 AND GRAB. J.BIOL.CHEM. V. 288 32466 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GNP C:202;
A:302;
E:202;
D:202;
B:202;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
MG D:201;
A:301;
E:201;
B:201;
C:201;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
MPD A:303;
Invalid;
none;
submit data
118.174 C6 H14 O2 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LHW 1.55 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF RAB8 IN ITS ACTIVE GPPNHP-BOUND FORM HOMO SAPIENS SMALL GTPASE PROTEIN TRANSPORT
Ref.: INTERMEDIATES IN THE GUANINE NUCLEOTIDE EXCHANGE RE RAB8 PROTEIN CATALYZED BY GUANINE NUCLEOTIDE EXCHAN FACTORS RABIN8 AND GRAB. J.BIOL.CHEM. V. 288 32466 2013
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4LHW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 4LHV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 175 families.
1 4LHW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 4LHV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1YZN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 3RWM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 3RWO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 2F9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 2F9M - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 1YZK - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 1OIV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 3NKV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 1G17 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 1G16 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 1OIX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 1OIW - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
15 3RAB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50% Homology Family (274)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 149 families.
1 1Z2A - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1Z22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1YZT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1YZU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 1Z08 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 1Z0I - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4DKX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 2Y8E - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 2A5J - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 4LHW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4LHV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 2P2L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 2W2V - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
14 1MH1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
15 2WKP - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
16 2WKR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
17 2WKQ - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
18 5WDO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
19 3TGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
20 1P2T - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
21 4Q01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
22 4M21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
23 6ARK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
24 821P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
25 1Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
26 5VPZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
27 6F76 - CVK C24 H26 N2 O3 CN(C)Cc1cc....
28 6Q21 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
29 4L9W - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
30 4WA7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
31 3V4F - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
32 3K9N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
33 5OCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
34 4M1T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
35 4XVQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
36 5V71 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
37 5VP7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
38 2QUZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
39 1CLU Kd = 5.4 nM DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
40 4L8G - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
41 5VBM - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
42 2RGD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
43 4PZY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
44 4LPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
45 4DLV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
46 4LRW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
47 2CLD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
48 4M1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
49 3L8Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50 3LBH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
51 721P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
52 1LF5 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
53 1GNR - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
54 4LUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
55 2RGE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
56 4DLS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
57 4M22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
58 4DLY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
59 1ZW6 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
60 2RGC - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
61 5VQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
62 5V9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
63 2CL0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
64 4TQA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
65 3RRZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
66 5VPY - 9GM C10 H17 N6 O13 P3 c1nc2c(n1[....
67 2EVW - XY2 C12 H15 N5 O4 CC(=O)N(C)....
68 2RGB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
69 4LDJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70 1XJ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
71 1ZVQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
72 5VQ6 - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
73 1P2S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
74 5V6V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
75 621P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
76 1P2V - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
77 2CL7 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
78 3OIW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
79 4LV6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
80 4DLT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
81 1P2U - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
82 5V6S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
83 5UK9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
84 6ASE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
85 3RS0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
86 5B30 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
87 5B2Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
88 3KKN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
89 4M1O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
90 5VQ0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
91 4M1Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
92 5VPI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
93 5W22 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
94 3I3S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
95 4OBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
96 3RRY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
97 1QRA - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
98 6BP1 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
99 4LYJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
100 121P - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
101 1RVD - DBG C23 H27 N8 O13 P3 c1ccc(cc1)....
102 5VBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
103 2RGA - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
104 3RS7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
105 5UHV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
106 2CLC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
107 4EPT - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
108 4EPY Kd = 340 uM 0QY C21 H21 N5 O c1ccc2c(c1....
109 4DLZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
110 1AGP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
111 1GNQ - CAG C18 H23 N6 O16 P3 C[C@H](c1c....
112 2Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
113 3RS2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
114 5VQ8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
115 4L9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
116 6B0Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
117 4M1S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
118 4EPV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
119 5WDP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
120 4TQ9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
121 3K8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
122 3OIV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
123 5OCT - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
124 5VBE - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
125 4Q02 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
126 3LBI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
127 3RSL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
128 1LF0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
129 1XCM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
130 421P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
131 4DLR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
132 2CE2 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
133 4QL3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
134 4Q21 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
135 4DLU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
136 1CTQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
137 3OIU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
138 6B0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
139 3RS5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
140 4EPW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
141 5WDQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
142 1IOZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
143 221P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
144 4LYH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
145 4DLX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
146 4Q03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
147 4PZZ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
148 3KKM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
149 1JAI - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
150 3L8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
151 3RS4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
152 3LBN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
153 4NMM - Y9Z C14 H22 N6 O12 P2 CC(=O)NCCO....
154 5VQ2 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
155 3RSO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
156 4XVR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
157 5P21 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
158 5F2E - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
159 4EPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
160 4EPR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
161 4DLW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
162 5WHD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
163 5V9O - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
164 5V9U - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
165 2RGG - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
166 4LYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
167 1JAH - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
168 1YU9 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
169 2BME - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
170 2BMD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
171 1YZN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
172 3RWM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
173 3RWO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
174 3REG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
175 2F9L - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
176 2F9M - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
177 1YZK - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
178 1OIV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
179 2FE4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
180 2FFQ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
181 2E9S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
182 5US4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
183 5UQW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
184 5USJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
185 3NKV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
186 1HUQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
187 1Z07 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
188 1N6R - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
189 1Z0D - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
190 1N6H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
191 1N6P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
192 1N6K - GDP AF3 n/a n/a
193 1N6N - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
194 1N6I - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
195 1R2Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
196 1N6L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
197 1N6O - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
198 1TU4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
199 1EK0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
200 1S8F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
201 1YZL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
202 1WMS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
203 1D5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
204 1Z0F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
205 3E5H - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
206 4DSU - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
207 4DST - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
208 4DSO - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
209 4DSN - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
210 5OCG - 9R5 C9 H10 Cl N O2 c1cc2c(cc1....
211 1KAO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
212 3RAP - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
213 1YZQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
214 2GIL - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
215 1Z0A - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
216 1KY2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
217 1KY3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
218 2HT6 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
219 3KKO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
220 3KKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
221 3KKP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
222 1X1R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
223 1X1S - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
224 1T91 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
225 1VG8 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
226 2GCP - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
227 2GCN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
228 3X1Z - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
229 3X1Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
230 3X1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
231 3X1X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
232 4Z8Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
233 1G17 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
234 1G16 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
235 1M7B - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
236 2DPX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
237 3Q7Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
238 3Q7P - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
239 3Q72 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
240 1U8Z - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
241 1U90 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
242 1U8Y - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
243 1YVD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
244 5WDR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
245 5WDS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
246 1Z06 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
247 3TH5 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
248 3SBD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
249 1OIX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
250 1OIW - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
251 2QRZ - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
252 1A4R Kd = 9.4 pM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
253 1KMQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
254 1DPF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
255 1FTN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
256 5A0F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
257 1A2B - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
258 4U5X - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
259 3Q85 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
260 1RYH - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
261 1RYF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
262 1VG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
263 5XC5 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
264 5XC3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
265 3RAB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
266 1GWN - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
267 2EW1 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
268 4O25 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
269 4O2R - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
270 4O2L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
271 6BSX - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
272 5YXH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
273 1XTQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
274 3SEA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GNP; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 9GM 1 1
3 GDP 0.839506 0.973684
4 GP3 0.82716 0.948718
5 GTP 0.809524 0.973684
6 GNH 0.807229 0.986842
7 G1R 0.77907 0.961039
8 GCP 0.77907 0.948718
9 GSP 0.770115 0.925
10 5GP 0.756098 0.960526
11 G 0.756098 0.960526
12 G2R 0.747253 0.936709
13 GMV 0.747126 0.948718
14 GAV 0.714286 0.936709
15 GP2 0.712644 0.936709
16 G2P 0.711111 0.936709
17 Y9Z 0.708333 0.880952
18 GDC 0.690722 0.936709
19 GDD 0.690722 0.936709
20 GKE 0.690722 0.936709
21 G5P 0.686869 0.948718
22 GPG 0.684211 0.936709
23 GTG 0.683673 0.91358
24 GDR 0.683673 0.936709
25 GFB 0.683673 0.936709
26 JB2 0.68 0.936709
27 GKD 0.68 0.936709
28 6CK 0.676768 0.91358
29 G3A 0.676768 0.948718
30 GDX 0.673267 0.948718
31 ALF 5GP 0.67033 0.86747
32 YGP 0.663265 0.879518
33 GPD 0.656863 0.902439
34 ALF GDP 0.645833 0.86747
35 GDP AF3 0.645833 0.86747
36 GDP ALF 0.645833 0.86747
37 JB3 0.641509 0.925
38 DBG 0.640351 0.974359
39 G3D 0.638298 0.960526
40 G4P 0.625 0.960526
41 GMP 0.621951 0.857143
42 NGD 0.62037 0.936709
43 GGM 0.618182 0.925926
44 0O2 0.616162 0.960526
45 2MD 0.603604 0.870588
46 CAG 0.60177 0.904762
47 U2G 0.590909 0.91358
48 FEG 0.590909 0.858824
49 GDP 7MG 0.590476 0.888889
50 MGD 0.587719 0.870588
51 G G 0.586538 0.924051
52 ZGP 0.585586 0.848837
53 CG2 0.580357 0.91358
54 ANP 0.568421 0.922078
55 PGD 0.567797 0.902439
56 MD1 0.567797 0.870588
57 3GP 0.56044 0.922078
58 TPG 0.558333 0.822222
59 GH3 0.55 0.948052
60 FE9 0.546219 0.778947
61 GPX 0.539216 0.922078
62 G4M 0.539062 0.860465
63 DGI 0.536082 0.9
64 BGO 0.535088 0.901235
65 IDP 0.53125 0.947368
66 DGT 0.53 0.9
67 2GP 0.526882 0.935065
68 G1R G1R 0.520325 0.901235
69 GCP G 0.518868 0.897436
70 A G 0.516949 0.911392
71 U A G G 0.512605 0.911392
72 G A A A 0.504202 0.9
73 AGO 0.504202 0.91358
74 P2G 0.5 0.860759
75 G1G 0.5 0.902439
76 R7I 0.49505 0.922078
77 MGP 0.49505 0.936709
78 R5I 0.49505 0.922078
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 AKW 0.483051 0.869048
83 DG 0.474227 0.8875
84 DGP 0.474227 0.8875
85 G U 0.466667 0.878049
86 IMP 0.463918 0.934211
87 G2Q 0.462963 0.936709
88 GPC 0.459677 0.858824
89 G C 0.459016 0.878049
90 GTA 0.448276 0.91358
91 G7M 0.444444 0.924051
92 MAP 0.439252 0.898734
93 G G G RPC 0.435484 0.853659
94 B4P 0.434343 0.871795
95 AP5 0.434343 0.871795
96 ADP 0.434343 0.896104
97 A2D 0.43299 0.871795
98 AT4 0.43 0.8625
99 G G G C 0.426357 0.890244
100 AU1 0.425743 0.922078
101 SGP 0.425743 0.807229
102 BA3 0.424242 0.871795
103 A G C C 0.423077 0.888889
104 35G 0.423077 0.909091
105 PCG 0.423077 0.909091
106 C2E 0.423077 0.897436
107 APC G U 0.421875 0.864198
108 HEJ 0.421569 0.896104
109 ATP 0.421569 0.896104
110 ACQ 0.419048 0.873418
111 5GP 5GP 0.419048 0.860759
112 5FA 0.417476 0.896104
113 AQP 0.417476 0.896104
114 01G 0.417391 0.880952
115 AN2 0.415842 0.909091
116 UNP 0.415842 0.810127
117 6AD 0.415094 0.821429
118 M33 0.411765 0.860759
119 ITT 0.411765 0.846154
120 G C C C 0.410448 0.901235
121 HFD 0.409524 0.851852
122 G U34 0.408 0.86747
123 ACP 0.407767 0.873418
124 6YZ 0.407407 0.873418
125 AR6 0.403846 0.871795
126 APR 0.403846 0.871795
127 DG DG 0.403509 0.845238
128 A4P 0.403226 0.848837
129 UCG 0.402985 0.888889
130 SAP 0.4 0.851852
131 AGS 0.4 0.851852
132 AD9 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LHW; Ligand: GNP; Similar sites found with APoc: 475
This union binding pocket(no: 1) in the query (biounit: 4lhw.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2GJ8 ALF GDP None
2 2PL3 ADP None
3 1GXU 2HP None
4 1VHT BA3 None
5 3BER AMP None
6 1W5T ADP None
7 4JLS 3ZE None
8 3HU3 AGS None
9 2DT9 THR None
10 2GNK ATP None
11 2Q8M AMP None
12 3GFS FMN None
13 1W5T ANP None
14 3QVV A3P None
15 1I1N SAH None
16 5WRI A3P None
17 5ZZO FLC None
18 2F59 INI None
19 1JJV ATP 1.14943
20 5XKT GNP 1.14943
21 4ZNL BEF ADP 1.14943
22 1FNZ A2G 1.14943
23 1M7G ADX 1.72414
24 3UIE ANP 1.72414
25 1M7G ADP 1.72414
26 6B4K ANP 1.72414
27 1M7G AV2 1.72414
28 3WV6 GAL GLC 1.72414
29 3I8T LBT 1.82927
30 4MZQ 1VU 2.08333
31 2BVN GNP 2.29885
32 2HCJ GDP 2.29885
33 1D8T GDP 2.29885
34 5GVR LMR 2.29885
35 1G7S GDP 2.29885
36 1D2E GDP 2.29885
37 1XMV ADP 2.29885
38 1VKJ A3P 2.29885
39 1ION ADP 2.29885
40 1G8S MET 2.29885
41 5U32 GDP 2.87356
42 1SVI GDP 2.87356
43 5ZBR ANP 2.87356
44 6DEF GCP 2.87356
45 5M04 GDP 2.87356
46 1U0J ADP 2.87356
47 4O48 ASP 2.87356
48 4GOX A3P 2.87356
49 5T63 ALA ALA ALA ALA 2.87356
50 5H4S RAM 2.87356
51 2Y65 ADP 3.44828
52 3E70 GDP 3.44828
53 3TBK ANP 3.44828
54 4DDY DN6 3.44828
55 4ZDJ UTP 3.44828
56 1FP6 ADP 3.44828
57 6AIC AMP 3.44828
58 3ITJ CIT 3.44828
59 4PJ3 ANP 3.44828
60 1YTM ATP 3.44828
61 3FSY SCA 3.44828
62 4B9E FAH 3.44828
63 3KC1 2T6 3.44828
64 2Z48 A2G 3.44828
65 4AG5 ADP 3.44828
66 4YS0 ADP 3.44828
67 4UOX PLP 3.44828
68 1TQ4 GDP 4.02299
69 5YT0 GDP 4.02299
70 5FG3 GDP 4.02299
71 2GKS ADP 4.02299
72 1G6O ADP 4.02299
73 1XP8 AGS 4.02299
74 4IDN GNP 4.02299
75 3DC4 ADP 4.02299
76 5BN3 ADP 4.02299
77 3IUY AMP 4.02299
78 1F9V ADP 4.02299
79 3QXC ATP 4.02299
80 4C25 13P 4.02299
81 4JAW GAL NGT 4.02299
82 4PVR ASP 4.02299
83 1IN4 ADP 4.02299
84 3FJG 3PG 4.02299
85 5ZB0 TYD 4.02299
86 5ZB0 ADP 4.02299
87 1P4V GLY 4.02299
88 5YLF BGC 4.02299
89 4JAW NGT GAL 4.02299
90 3DKP ADP 4.02299
91 1Z83 AP5 4.02299
92 2WPB ZZI 4.02299
93 4A34 FUL 4.08163
94 2IYL GDP 4.57746
95 3A1S GDP 4.5977
96 2HF9 GSP 4.5977
97 3KJI ADP 4.5977
98 4IEE AGS 4.5977
99 2D7D ADP 4.5977
100 1DAK DPU 4.5977
101 1DAK ADP 4.5977
102 2C9O ADP 4.5977
103 1F76 ORO 4.5977
104 3BFX A3P 4.5977
105 3P4X ADP 4.5977
106 1K6M AGS 4.5977
107 1HSL HIS 4.5977
108 1T5C ADP 4.5977
109 1SVM ATP 4.5977
110 5MEX PAP 4.65839
111 1APZ ASP 4.93827
112 1YRB GDP 5.17241
113 1KK1 GNP 5.17241
114 1JJ7 ADP 5.17241
115 5YV5 ADP 5.17241
116 1YQT ADP 5.17241
117 1JI0 ATP 5.17241
118 1H65 GDP 5.17241
119 1DAR GDP 5.17241
120 2D2F ADP 5.17241
121 3DEF GDP 5.17241
122 1KK8 BEF ADP 5.17241
123 4FCW ADP 5.17241
124 4LJ9 ACP 5.17241
125 3KTA AP5 5.17241
126 2Q2Y ADP 5.17241
127 1QF5 GDP 5.17241
128 1QF5 RPL 5.17241
129 2Q2Y MKR 5.17241
130 1B7T ADP 5.17241
131 4A4Z ANP 5.17241
132 5NM7 GLY 5.17241
133 2VVG ADP 5.17241
134 2FAH GDP 5.17241
135 2J5V PCA 5.17241
136 6B8B ADP 5.17241
137 2IXE ATP 5.17241
138 2RGX AP5 5.17241
139 2ZJ5 ADP 5.17241
140 1ZIN AP5 5.17241
141 1CR1 TTP 5.17241
142 4X8O AP5 5.17241
143 1SQ5 ADP 5.17241
144 3V1S 0LH 5.17241
145 1B4P GPS 5.17241
146 3AB4 THR 5.17241
147 4BFW ZVW 5.17241
148 1UKZ ADP 5.17241
149 1XEX ATP 5.17241
150 3BP1 GUN 5.17241
151 1SLT NDG GAL 5.22388
152 3KIF GDL 5.66038
153 2FH5 GTP 5.74713
154 2W58 ADP 5.74713
155 3WXM GTP 5.74713
156 1G7C 5GP 5.74713
157 2RCN GDP 5.74713
158 5TSH ADP 5.74713
159 5I0H ADP BEF 5.74713
160 5TSH ANP 5.74713
161 4ZG4 VO4 ADP 5.74713
162 3MD0 GDP 5.74713
163 2WIC GNP 5.74713
164 3BOS CDP 5.74713
165 1LVK MNT BEF 5.74713
166 1W7J ADP BEF 5.74713
167 2B8W ALF 5GP 5.74713
168 4R98 GNH 5.74713
169 5L3V GDP 5.74713
170 4PFO ADP 5.74713
171 1IHU ADP 5.74713
172 1IHU AF3 5.74713
173 2BEK ATP 5.74713
174 3IIJ ADP 5.74713
175 4U60 SIA GAL NGA 5.74713
176 3DZD ADP 5.74713
177 1OS1 PYR 5.74713
178 4U60 SIA 5.74713
179 3FB4 AP5 5.74713
180 1TL2 NDG 5.74713
181 2Z5F A3P 5.74713
182 2QQ0 ANP 5.74713
183 4R43 GDP 5.74713
184 1LK7 DER 5.74713
185 2QQ0 TMP 5.74713
186 2QQ0 ADP 5.74713
187 1U2Z SAH 5.74713
188 1OS1 ATP 5.74713
189 1CZR FMN 5.91716
190 5W97 CHD 6.12245
191 4WOP CTP 6.22222
192 4NCN GTP 6.32184
193 1BH2 GSP 6.32184
194 1TAD ALF 6.32184
195 1TAD GDP 6.32184
196 1G6H ADP 6.32184
197 6AU6 GDP 6.32184
198 1FQJ ALF 6.32184
199 1FQJ GDP 6.32184
200 1SVK ALF GDP 6.32184
201 4NON GDP 6.32184
202 1FQK GDP 6.32184
203 1Y3A GDP 6.32184
204 3PQC GDP 6.32184
205 2XTN GTP 6.32184
206 3EC1 GDP 6.32184
207 6CRK GDP 6.32184
208 3ZFD ANP 6.32184
209 1GP2 GDP 6.32184
210 2OM2 GDP 6.32184
211 5KDO GDP 6.32184
212 3UG4 AHR 6.32184
213 5L3S GNP 6.32184
214 2WOJ ADP ALF 6.32184
215 2FSH ANP 6.32184
216 2CHG ANP 6.32184
217 2ZPA ADP 6.32184
218 5L3W GDP 6.32184
219 4TL6 ANP 6.32184
220 2QEN ADP 6.32184
221 3FVQ ATP 6.32184
222 3QKT ANP 6.32184
223 5EXT ADP 6.32184
224 1NY5 ADP 6.32184
225 4MKF AP5 6.32184
226 5X40 ACP 6.32184
227 3BFV ADP 6.32184
228 1FQK ALF 6.32184
229 2DPY ADP 6.32184
230 5JBE MAL 6.32184
231 1B0U ATP 6.32184
232 4PX9 ADP 6.50685
233 1M26 GAL A2G 6.76692
234 1WF3 GNP 6.89655
235 2WHX ADP 6.89655
236 2OG2 MLI 6.89655
237 4HI0 GDP 6.89655
238 4P4T GDP 6.89655
239 1XX6 ADP 6.89655
240 1W0J ADP 6.89655
241 4HSE ADP 6.89655
242 1W0J ADP BEF 6.89655
243 1G3Q ADP 6.89655
244 1R6B ADP 6.89655
245 5ZRR 9J3 6.89655
246 4YMU ATP 6.89655
247 6AR9 3L4 6.89655
248 2I4I AMP 6.89655
249 1NRJ GTP 6.96203
250 2WJH GDP 7.22892
251 2WJH FLC 7.22892
252 3NIM ARG ARG ALA ALA 7.31707
253 1SKQ GDP 7.47126
254 3CX8 GSP 7.47126
255 4U00 ADP 7.47126
256 3B9Q MLI 7.47126
257 3TK1 GDP 7.47126
258 1FNN ADP 7.47126
259 1GOJ ADP 7.47126
260 1X6V ADP 7.47126
261 2FHE GSH 7.47126
262 2XAU ADP 7.47126
263 5ZXD ATP 7.47126
264 2ODE ALF GDP 7.80142
265 5UIV ADP 7.92952
266 4DCT GDP 8.04598
267 2XTZ GSP 8.04598
268 4WZ6 ATP 8.04598
269 5HCN GCP 8.04598
270 5CK5 GDP 8.04598
271 3B5J 12D 8.04598
272 4IHQ ADP 8.04598
273 5Y6N ADP 8.04598
274 5N69 ADP 8.04598
275 1E2K TMC 8.04598
276 2OFW ADX 8.04598
277 3RC3 ANP 8.04598
278 2PEZ GGZ 8.04598
279 2PEZ DAT 8.04598
280 4MKG AP5 8.04598
281 1KO8 6PG 8.04598
282 1QHG ATP 8.04598
283 3NHB ADP 8.04598
284 1WY7 SAH 8.04598
285 6H45 QEI 8.04598
286 5AO7 NAG 8.04598
287 3COB ADP 8.62069
288 1RRC ADP 8.62069
289 4KFU ACP 8.62069
290 2CDN ADP 8.62069
291 2WJG GDP 8.62069
292 2IS6 ADP 8.62069
293 3ZQ6 ADP ALF 8.62069
294 4R2I ANP 8.62069
295 4XVU ATP 8.62069
296 5Z69 AGS 8.62069
297 4RF7 ARG 8.62069
298 4NU0 AP5 8.62069
299 1S3G AP5 8.62069
300 1TLC DGP 8.62069
301 1PUJ GNP 9.1954
302 4WZA ACP 9.1954
303 4WZA ADP 9.1954
304 5L3R GCP 9.1954
305 5MZN ADP 9.1954
306 3VM7 GLC 9.1954
307 2BIF ANP 9.1954
308 2BIF SIN 9.1954
309 4NE2 SH2 9.1954
310 1AKY AP5 9.1954
311 4NE2 ADP 9.1954
312 3JQF AX2 9.1954
313 4QOS ADP 9.1954
314 1QHH ATP 9.1954
315 1F2U ATP 9.45946
316 2GK6 ADP 9.77011
317 2CE7 ADP 9.77011
318 1BG2 ADP 9.77011
319 1NHX FTB 9.77011
320 4IOK ADP 9.77011
321 1NHX PEP 9.77011
322 1NST A3P 9.77011
323 4IOK XPO 9.77011
324 2GMV UN8 9.77011
325 1UJ2 ADP 9.77011
326 1UJ2 C5P 9.77011
327 1D2N ANP 9.77011
328 1Q19 SSC 9.77011
329 3KIH GDL 10.3093
330 2XT3 ADP 10.3448
331 5KUT GDP 10.3448
332 3AB3 GDP 10.3448
333 3FWY ADP 10.3448
334 1OYY AGS 10.3448
335 4Q1A 2XZ 10.3448
336 4Q1A UDP 10.3448
337 2QZ4 ADP 10.3448
338 2NCD ADP 10.3448
339 3H86 AP5 10.3448
340 1P72 ADP 10.3448
341 1OXV ANP 10.3448
342 1R18 SAH 10.3448
343 3B7G ANP 10.3448
344 1M2Z BOG 10.3448
345 3QOX SAH 10.3448
346 2VB6 ADP BEF 10.7383
347 1F5N GNP 10.9195
348 5AK0 8V1 10.9195
349 4PU6 ASP 10.9195
350 2O0J ADP 10.9195
351 5HR5 ADP 10.9195
352 4QM7 GTP 11.1111
353 2C78 GNP 11.4943
354 2C77 GNP 11.4943
355 1L2T ATP 11.4943
356 4D81 ADP 11.4943
357 1A78 TDG 11.9403
358 1Y2W NAG 11.9718
359 1CS4 GSP 12.069
360 1LVG ADP 12.069
361 4LPS GDP 12.069
362 2GDJ ANP 12.069
363 3R7F CP 12.069
364 3FYH ADP 12.069
365 1BO4 COA 12.5
366 5LB3 ADP 12.6437
367 1Z6T ADP 12.6437
368 2X7I CIT 12.6437
369 4QRH 0O2 12.6437
370 1AQU A3P 12.6437
371 3ZIA ADP 12.6984
372 3ZIA ATP 12.6984
373 4OI4 ATP 13.0435
374 4RD0 GDP 13.2184
375 2QN6 GDP 13.2184
376 4LC1 GDP 13.2184
377 2ZR9 DTP 13.2184
378 4TTQ ATP 13.2184
379 1OFH ADP 13.2184
380 3QDK QDK 13.2184
381 1ME8 RVP 13.2184
382 1G41 ADP 13.7931
383 5LX9 OLB 13.7931
384 3QF7 ANP 14
385 5BQ5 ADP BEF 14.3678
386 6C90 ADP 14.3678
387 4KBF AMP 14.3678
388 3RLF ANP 14.9425
389 2AWN ADP 14.9425
390 1SQL GUN 15.0685
391 2GWH A3P 15.5172
392 2JBH 5GP 15.5172
393 1KJ8 GAR 15.5172
394 2KIN ADP 16
395 3H4S ADP 16.092
396 4FRZ ADP 16.092
397 4XTR ATP 16.2162
398 4XTR ADP 16.2162
399 4CVN ADP 16.7539
400 1XKV ATP 17.2414
401 4GBM A3P 17.2414
402 6G14 G4P 17.8161
403 5E5U MLI 17.8161
404 2CK3 ADP 18
405 2V7Q ATP 18
406 2CK3 ANP 18
407 2V7Q ADP 18
408 1NN5 ANP 18.3908
409 1NN5 2DT 18.3908
410 1P9B HDA 18.9655
411 1P9B GDP 18.9655
412 1V8K ANP 19.5402
413 4H1V GNP 19.5402
414 4BQS ADP 19.5402
415 4BQS K2Q 19.5402
416 4B47 GDP 20.1149
417 3VX3 ADP 20.1149
418 1ZUI SKM 20.2381
419 2ZFI ADP 20.6897
420 5TCI MLI 21.2644
421 1IWE IMP 21.8391
422 5I34 GDP 21.8391
423 5KSP GDP 22.4138
424 3T12 GDP ALF 22.4138
425 1YZG GDP 22.4138
426 5KSZ GCP 22.4138
427 3T1O GDP 22.4138
428 2JLR ANP 24.1379
429 3W5J GDP 24.7126
430 4M9Q GNP 25.8621
431 4BAS GNP 27.0115
432 1RJ9 GCP 27.5862
433 1NJF ADP 29.8851
434 1NJF AGS 29.8851
435 1M2O GNP 31.0345
436 1GOT GDP 31.5068
437 2QTV GNP 32.3353
438 4V0K GDP 33.1361
439 1ZD9 GDP 33.3333
440 6CS8 F9Y 33.3333
441 1ZJ6 G3D 33.908
442 3A4M ADP 33.908
443 1KSH GDP 34.4828
444 2A5F GTP 36.7816
445 1MR3 G3D 37.3563
446 1J2J GTP 38.5542
447 1O3Y GTP 38.5542
448 2ZEJ GDP 39.0805
449 1F6B GDP 39.0805
450 1RE0 GDP 39.6341
451 1S9D GDP 39.6341
452 3ZS9 ADP ALF 42.1053
453 1FZQ GDP 42.5414
454 1UPT GTP 44.4444
455 1R4A GNP 44.8485
456 1E96 GTP 47.1264
457 3REF GDP 47.1264
458 2FJU GSP 47.7011
459 1HE1 GDP 47.7011
460 3T5G GDP 47.7011
461 1I4D GDP 47.7011
462 1G4U GDP 47.7011
463 1HE1 AF3 47.7011
464 1MKY GDP 47.7011
465 1G4U AF3 47.7011
466 2W2X GSP 48.2759
467 5UPK GNP 48.8506
468 1NF3 GNP 48.8506
469 1DS6 GDP 48.8506
470 1GRN GDP 49.4253
471 4ITR GDP 49.4253
472 1GRN AF3 49.4253
473 2NGR GDP 49.4253
474 4DID GDP 49.4253
475 2NGR AF3 49.4253
476 3M1I GTP 50
477 3GJ7 GDP 50
478 3GJ4 GDP 50
479 3GJ5 GDP 50
480 3GJ8 GDP 50
Pocket No.: 2; Query (leader) PDB : 4LHW; Ligand: GNP; Similar sites found with APoc: 28
This union binding pocket(no: 2) in the query (biounit: 4lhw.bio3) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 5WRJ A3P None
2 1UJ5 5RP 1.14943
3 1QF9 C5P 1.72414
4 1QF9 ALF 1.72414
5 1QF9 ADP 1.72414
6 2ZL4 ALA ALA ALA ALA 2.29885
7 2WZF BGC 2.87356
8 4TQK NAG 2.87356
9 1YXM ADE 2.87356
10 2XCU C5P 2.87356
11 4LZB URA 2.87356
12 4G5H UD7 3.44828
13 3CEV ARG 3.44828
14 1VMK GUN 3.44828
15 5JAQ NAI 4.02299
16 4I7E PEP 4.02299
17 3LN9 FLC 4.31655
18 4EIL FOL 5.17241
19 5BSH PRO 5.74713
20 1O8B ABF 6.89655
21 4NSQ COA 6.89655
22 1DNP MHF 7.47126
23 3CTR MGP 7.92079
24 1W4R TTP 8.04598
25 1DCP HBI 11.5385
26 2A19 ANP 13.2184
27 2EFX NFA 13.7931
28 4LHD GLY 24.7126
Pocket No.: 3; Query (leader) PDB : 4LHW; Ligand: GNP; Similar sites found with APoc: 26
This union binding pocket(no: 3) in the query (biounit: 4lhw.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 3VPD CIT None
2 2Z9I GLY ALA THR VAL None
3 1J6X MET None
4 2Q37 3AL 1.14943
5 2JBM SRT 1.72414
6 3W6G FLC 1.72414
7 1GET FAD 2.87356
8 1GET NAP 2.87356
9 4UOX PUT 3.44828
10 2Z49 AMG 3.44828
11 1MJT ITU 4.02299
12 1ZQ9 SAM 4.5977
13 4MDB RLT 5.17241
14 1QAN SAH 5.17241
15 1BC5 SAH 5.17241
16 4HE2 AMP 6.32184
17 5L3S G 6.32184
18 1T3D CYS 6.89655
19 3MGB PAP 7.47126
20 1M0S CIT 8.04598
21 5A1S FLC 8.62069
22 4AP9 1PS 8.62069
23 5FII PHE 8.82353
24 5G09 6DF 10.3448
25 5OCQ CIT 11.4943
26 1VBH PEP 12.069
Pocket No.: 4; Query (leader) PDB : 4LHW; Ligand: GNP; Similar sites found with APoc: 12
This union binding pocket(no: 4) in the query (biounit: 4lhw.bio5) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 1OSS BEN 2.87356
2 3TW1 AHN 3.44828
3 2WGV CIT 4.02299
4 3THR C2F 5.17241
5 2YOH WMJ 5.17241
6 1JS8 MAN MAN BMA 5.74713
7 2GJ5 VD3 6.79012
8 2QG6 NMN 9.1954
9 2GMV PEP 9.77011
10 3TMK T5A 9.77011
11 1C3X 8IG 10.3448
12 3HCH RSM 16.4384
Pocket No.: 5; Query (leader) PDB : 4LHW; Ligand: GNP; Similar sites found with APoc: 16
This union binding pocket(no: 5) in the query (biounit: 4lhw.bio4) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 5AOG IAC None
2 4ARU TLA None
3 1UO4 PIH None
4 4LNP VAL PRO PRO PRO ARG PRO PRO PRO PRO GLU None
5 1A0J BEN 1.72414
6 4DD8 BAT 2.29885
7 1ONI BEZ 3.62319
8 3GUZ PAF 5.74713
9 5J47 6JJ 6.32184
10 1LOJ U 6.89655
11 1LOJ URI 6.89655
12 2PS1 ORO 7.47126
13 1XF1 CIT 7.47126
14 3B8I OXL 13.7931
15 6AM8 TRP 16.092
16 5DT6 GLU 17.2414
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