Receptor
PDB id Resolution Class Description Source Keywords
4LHD 1.8 Å EC: 1.4.4.2 CRYSTAL STRUCTURE OF SYNECHOCYSTIS SP. PCC 6803 GLYCINE DECA (P-PROTEIN), HOLO FORM WITH PYRIDOXAL-5'-PHOSPHATE AND GLYCC LOSED FLEXIBLE LOOP SYNECHOCYSTIS SP. ALPHA(2) HOMODIMER DEHYDROGENASE (DECARBOXYLATING) COFACTOPYRIDOXAL 5-prime -PHOSPHATE OXIDOREDUCTASE
Ref.: STRUCTURE OF THE HOMODIMERIC GLYCINE DECARBOXYLASE FROM SYNECHOCYSTIS SP. PCC 6803 SUGGESTS A MECHANIS REDOX REGULATION. J.BIOL.CHEM. V. 288 35333 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PO4 A:1009;
B:1004;
A:1008;
B:1005;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
GLY A:1004;
B:1001;
A:1003;
A:1002;
B:1002;
A:1001;
Invalid;
Valid;
Invalid;
Invalid;
Invalid;
Valid;
none;
none;
none;
none;
none;
none;
submit data
75.067 C2 H5 N O2 C(C(=...
EDO A:1010;
A:1014;
B:1006;
B:1008;
A:1013;
B:1009;
A:1011;
B:1007;
A:1017;
A:1015;
A:1012;
A:1016;
B:1010;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
BCT B:1003;
A:1007;
A:1005;
A:1006;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
61.017 C H O3 C(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LHD 1.8 Å EC: 1.4.4.2 CRYSTAL STRUCTURE OF SYNECHOCYSTIS SP. PCC 6803 GLYCINE DECA (P-PROTEIN), HOLO FORM WITH PYRIDOXAL-5'-PHOSPHATE AND GLYCC LOSED FLEXIBLE LOOP SYNECHOCYSTIS SP. ALPHA(2) HOMODIMER DEHYDROGENASE (DECARBOXYLATING) COFACTOPYRIDOXAL 5-prime -PHOSPHATE OXIDOREDUCTASE
Ref.: STRUCTURE OF THE HOMODIMERIC GLYCINE DECARBOXYLASE FROM SYNECHOCYSTIS SP. PCC 6803 SUGGESTS A MECHANIS REDOX REGULATION. J.BIOL.CHEM. V. 288 35333 2013
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4LHC - GLY C2 H5 N O2 C(C(=O)O)N
2 4LHD - GLY C2 H5 N O2 C(C(=O)O)N
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4LHC - GLY C2 H5 N O2 C(C(=O)O)N
2 4LHD - GLY C2 H5 N O2 C(C(=O)O)N
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4LHC - GLY C2 H5 N O2 C(C(=O)O)N
2 4LHD - GLY C2 H5 N O2 C(C(=O)O)N
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GLY; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 GLY 1 1
2 BAL 0.5625 0.708333
3 ABU 0.473684 0.708333
4 MCR 0.466667 0.65
5 2RA 0.421053 0.692308
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LHD; Ligand: GLY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4lhd.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4LHD; Ligand: GLY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4lhd.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4LHD; Ligand: GLY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4lhd.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4LHD; Ligand: GLY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4lhd.bio1) has 1 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4LHD; Ligand: GLY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 4lhd.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 4LHD; Ligand: GLY; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4lhd.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
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