Receptor
PDB id Resolution Class Description Source Keywords
4LCQ 1.81 Å EC: 7.-.-.- THE CRYSTAL STRUCTURE OF DI-ZN DIHYDROPYRIMIDINASE IN COMPLE NCBI TETRAODON NIGROVIRIDIS HYDROLASE ZINC BINDING CARBOXYLATION ALPHA-BETA BARREL HACTIVATOR
Ref.: CRYSTAL STRUCTURES OF VERTEBRATE DIHYDROPYRIMIDINAS COMPLEXES FROM TETRAODON NIGROVIRIDIS WITH LYSINE CARBAMYLATION: METAL AND STRUCTURAL REQUIREMENTS FO POST-TRANSLATIONAL MODIFICATION AND FUNCTION. J.BIOL.CHEM. V. 288 30645 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ZN A:602;
A:601;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
URQ A:603;
Valid;
none;
submit data
146.144 C5 H10 N2 O3 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LCQ 1.81 Å EC: 7.-.-.- THE CRYSTAL STRUCTURE OF DI-ZN DIHYDROPYRIMIDINASE IN COMPLE NCBI TETRAODON NIGROVIRIDIS HYDROLASE ZINC BINDING CARBOXYLATION ALPHA-BETA BARREL HACTIVATOR
Ref.: CRYSTAL STRUCTURES OF VERTEBRATE DIHYDROPYRIMIDINAS COMPLEXES FROM TETRAODON NIGROVIRIDIS WITH LYSINE CARBAMYLATION: METAL AND STRUCTURAL REQUIREMENTS FO POST-TRANSLATIONAL MODIFICATION AND FUNCTION. J.BIOL.CHEM. V. 288 30645 2013
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 311 families.
1 4LCQ - URQ C5 H10 N2 O3 C[C@@H](CN....
2 4LCR - URP C4 H8 N2 O3 C(CNC(=O)N....
3 4LCS - HYN C3 H4 N2 O2 C1C(=O)NC(....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 266 families.
1 4LCQ - URQ C5 H10 N2 O3 C[C@@H](CN....
2 4LCR - URP C4 H8 N2 O3 C(CNC(=O)N....
3 4LCS - HYN C3 H4 N2 O2 C1C(=O)NC(....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 218 families.
1 6KLK Kd = 133.2 uM URF C4 H3 F N2 O2 C1=C(C(=O)....
2 4LCQ - URQ C5 H10 N2 O3 C[C@@H](CN....
3 4LCR - URP C4 H8 N2 O3 C(CNC(=O)N....
4 4LCS - HYN C3 H4 N2 O2 C1C(=O)NC(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: URQ; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 URQ 1 1
2 CDV 0.40625 0.638889
3 UGC 0.4 0.648649
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LCQ; Ligand: URQ; Similar sites found with APoc: 4
This union binding pocket(no: 1) in the query (biounit: 4lcq.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 2FVK DUC 49.4231
2 2FVK DUC 49.4231
3 2FVK DUC 49.4231
4 2FVK DUC 49.4231
Pocket No.: 2; Query (leader) PDB : 4LCQ; Ligand: URQ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4lcq.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4LCQ; Ligand: URQ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4lcq.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4LCQ; Ligand: URQ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4lcq.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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