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Receptor
PDB id Resolution Class Description Source Keywords
4LC1 1.8 Å EC: 3.-.-.- MEAB, A BACTERIAL HOMOLOG OF MMAA, BOUND TO GDP AND CRYSTALL THE PRESENCE OF GDP AND [ALF4]- METHYLOBACTERIUM EXTORQUENS ALPHA AND BETA PROTEIN METALLOCHAPERONE CHAPERONE
Ref.: AUTOINHIBITION AND SIGNALING BY THE SWITCH II MOTIF G-PROTEIN CHAPERONE OF A RADICAL B12 ENZYME. J.BIOL.CHEM. V. 288 30980 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP B:401;
A:401;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
GOL A:402;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LC1 1.8 Å EC: 3.-.-.- MEAB, A BACTERIAL HOMOLOG OF MMAA, BOUND TO GDP AND CRYSTALL THE PRESENCE OF GDP AND [ALF4]- METHYLOBACTERIUM EXTORQUENS ALPHA AND BETA PROTEIN METALLOCHAPERONE CHAPERONE
Ref.: AUTOINHIBITION AND SIGNALING BY THE SWITCH II MOTIF G-PROTEIN CHAPERONE OF A RADICAL B12 ENZYME. J.BIOL.CHEM. V. 288 30980 2013
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 4JYB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 2QM7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4JYC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4LC1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 4JYB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 2QM7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4JYC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4LC1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 173 families.
1 3MD0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4JYB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 2QM7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4JYC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 4LC1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 3TK1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LC1; Ligand: GDP; Similar sites found with APoc: 688
This union binding pocket(no: 1) in the query (biounit: 4lc1.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 2FNA ADP 0.890208
2 1AQU A3P 1.0101
3 5WDR GNP 1.16959
4 4WEI GLC GAL 1.44404
5 1V8K ANP 1.48368
6 1XKV ATP 1.48368
7 1SVM ATP 1.48368
8 5Y6N ADP 1.48368
9 3ITJ CIT 1.48368
10 1F5N GNP 1.48368
11 2A5J GDP 1.57068
12 1YZN GNP 1.62162
13 3DKP ADP 1.63265
14 2PL3 ADP 1.69492
15 1R2Q GNP 1.76471
16 5FG3 GDP 1.78042
17 5YT0 GDP 1.78042
18 5GOE GDP 1.78042
19 2Y65 ADP 1.78042
20 4NCN GTP 1.78042
21 4TMZ GSP 1.78042
22 3P4X ADP 1.78042
23 2JLR ANP 1.78042
24 1T5C ADP 1.78042
25 2XAU ADP 1.78042
26 2ZPA ADP 1.78042
27 2QA1 FAD 1.78042
28 1X8J A3P 1.78042
29 3MJH GTP 1.78571
30 4DDY DN6 1.90114
31 5EJ2 NAD 1.94805
32 2Z5F A3P 2.01342
33 1T3D CYS 2.07612
34 5IRN ADP 2.07715
35 1OS1 PYR 2.07715
36 1OS1 ATP 2.07715
37 5LTJ ADP 2.07715
38 2CE7 ADP 2.07715
39 6FAA ADP 2.07715
40 1P9B GDP 2.07715
41 5LTJ BEF 2.07715
42 4UP4 GAL NAG 2.07715
43 1GET NAP 2.07715
44 1GZ4 ATP 2.07715
45 1GET FAD 2.07715
46 1S7N COA 2.1978
47 5CK5 GDP 2.21519
48 1B0U ATP 2.29008
49 2ZW5 COA 2.32558
50 1G6H ADP 2.33463
51 1EK0 GNP 2.35294
52 1H74 ADP 2.36486
53 1H74 ILE 2.36486
54 2ZPT A3P 2.37288
55 1GOJ ADP 2.37389
56 4H1V GNP 2.37389
57 5VHC BEF ADP 2.37389
58 1QF5 RPL 2.37389
59 1QF5 GDP 2.37389
60 4PX9 ADP 2.39726
61 4U00 ADP 2.45902
62 2ORV 4TA 2.5641
63 5GVR LMR 2.5641
64 2X7I CIT 2.5974
65 3TKL GTP 2.62172
66 5KUT GDP 2.6455
67 3SFV GDP 2.67062
68 1DAR GDP 2.67062
69 6AU6 GDP 2.67062
70 4PPF FLC 2.67062
71 5ZXD ATP 2.67062
72 3FVQ ATP 2.67062
73 2ZR9 DTP 2.67062
74 1ZCB GDP 2.67062
75 6B4K ANP 2.67062
76 2FSH ANP 2.67062
77 2JJK R15 2.67062
78 4UTG ANP 2.67062
79 2GWH A3P 2.68456
80 1MH1 GNP 2.68817
81 1G4U GDP 2.71739
82 4LYA ATP 2.86225
83 1EDO NAP 2.86885
84 1Z0A GDP 2.87356
85 5K2M ADP 2.9304
86 1D2N ANP 2.94118
87 4RF2 NAP 2.94118
88 2R75 01G 2.95858
89 2O66 FLC 2.96296
90 5W76 GDP 2.96736
91 2FJU GSP 2.96736
92 5BN3 ADP 2.96736
93 3DC4 ADP 2.96736
94 1XP8 AGS 2.96736
95 4IEE AGS 2.96736
96 1PVN MZP 2.96736
97 4I4B NAD 2.96736
98 3RC3 ANP 2.96736
99 2GCO GNP 2.98507
100 2GCN GDP 2.98507
101 2ZFI ADP 3.00546
102 1F6B GDP 3.0303
103 5O74 GDP 3.04569
104 1W4R TTP 3.07692
105 3AFN NAP 3.10078
106 4WZ6 ATP 3.10345
107 1OJ4 ANP 3.18021
108 4DKX GDP 3.24074
109 2C9O ADP 3.2641
110 4HSE ADP 3.2641
111 2AWN ADP 3.2641
112 5N69 ADP 3.2641
113 3QKT ANP 3.2641
114 4YS0 ADP 3.2641
115 4PJ3 ANP 3.2641
116 4ITM ATP 3.2641
117 5MB4 NAG 3.2641
118 2WKQ GTP 3.31325
119 1RRC ADP 3.32226
120 1DS6 GDP 3.33333
121 1H65 GDP 3.33333
122 1X1R GDP 3.37079
123 1L2T ATP 3.40426
124 5X40 ACP 3.42466
125 1RYH GNP 3.44828
126 3MGB PAP 3.44828
127 1JJ7 ADP 3.46154
128 1R0X ATP 3.4965
129 5ZB0 TYD 3.53535
130 5ZB0 ADP 3.53535
131 2RCN GDP 3.56083
132 2W58 ADP 3.56083
133 3COB ADP 3.56083
134 1OXV ANP 3.56083
135 4OHY ANP 3.56083
136 1IWE IMP 3.56083
137 1XMV ADP 3.56083
138 1Z6T ADP 3.56083
139 3TBK ANP 3.56083
140 5I34 GDP 3.56083
141 1FNN ADP 3.56083
142 1OYY AGS 3.56083
143 2RAB FAD 3.56083
144 4Y4V DAL 3.56083
145 6H5E ANP 3.56083
146 5G41 AP5 3.58744
147 1NJF ADP 3.6
148 1NJF AGS 3.6
149 6EDV COA 3.60825
150 2VBQ BSJ 3.63636
151 4ZNL BEF ADP 3.64964
152 1AE1 NAP 3.663
153 5LEF GTP 3.66492
154 4NU0 AP5 3.68664
155 4MKF AP5 3.68664
156 6AIC AMP 3.73832
157 1U0J ADP 3.74532
158 5AHM IMP 3.75
159 2J0V GDP 3.77358
160 4QOS ADP 3.77358
161 2KIN ADP 3.78151
162 2ZEJ GDP 3.80435
163 4GOX A3P 3.83387
164 4NON GDP 3.84615
165 4B47 GDP 3.85757
166 5TSH ADP 3.85757
167 5TSH ANP 3.85757
168 5WC2 ADP 3.85757
169 1F9V ADP 3.85757
170 4XGU ADP 3.85757
171 1K6M AGS 3.85757
172 2J5V PCA 3.85757
173 5K04 COA 3.85757
174 4TQK NAG 3.85757
175 5J1J ANP 3.85965
176 5H4S RAM 3.87324
177 4G86 BNT 3.87324
178 1P72 ADP 3.89222
179 5EP2 AZU 3.90625
180 2Y8E GNP 3.91061
181 3WY9 GDP 3.91705
182 3WYA GDP 3.91705
183 6BSX GDP 3.93258
184 6BSX E7S 3.93258
185 5G3Y ADP 3.9823
186 1KO8 6PG 4
187 6B8B ADP 4.01606
188 4YLG GDP 4.04624
189 1IXI 2HP 4.04984
190 1G3M PCQ 4.08163
191 1G3M A3P 4.08163
192 2FFQ GSP 4.09357
193 4QM7 GTP 4.09357
194 1J99 AND 4.09556
195 4GDX GLU 4.10256
196 1YZQ GNP 4.11765
197 5H68 AGS 4.11765
198 1QF9 ALF 4.12371
199 1QF9 C5P 4.12371
200 1QF9 ADP 4.12371
201 1D2E GDP 4.1543
202 2C78 GNP 4.1543
203 5W7Q GDP 4.1543
204 2C77 GNP 4.1543
205 1SKQ GDP 4.1543
206 4IDN GNP 4.1543
207 1LVK MNT BEF 4.1543
208 5M7P ADP 4.1543
209 2D7D ADP 4.1543
210 5BRE 4UZ 4.1543
211 1KAO GDP 4.19162
212 4NE2 ADP 4.19162
213 4NE2 SH2 4.19162
214 1IN4 ADP 4.19162
215 4D81 ADP 4.24028
216 4Q1A 2XZ 4.28571
217 4Q1A UDP 4.28571
218 5MVR ADP 4.32099
219 3RWO GDP 4.32432
220 3IUY AMP 4.38596
221 4ZKD GDP 4.45104
222 2BIF SIN 4.45104
223 2BIF ANP 4.45104
224 5HR5 ADP 4.45104
225 3EZ2 ADP 4.45104
226 3DZD ADP 4.45104
227 4YJ1 ADP 4.45104
228 2A2C NG1 4.45104
229 2A2C ADP 4.45104
230 5MZI FAD 4.45104
231 5MZI FYK 4.45104
232 3GJ3 GDP 4.52489
233 3GJ4 GDP 4.52489
234 3GJ5 GDP 4.52489
235 1SQ5 ADP 4.54545
236 1ZIN AP5 4.60829
237 4MKG AP5 4.60829
238 1BG2 ADP 4.61538
239 5EXT ADP 4.61538
240 3FB4 AP5 4.62963
241 2CBZ ATP 4.64135
242 3A28 NAD 4.65116
243 4X8O AP5 4.6729
244 1M2O GNP 4.73684
245 1TQ4 GDP 4.74777
246 5KDO GDP 4.74777
247 5FHD ADP ALF 4.74777
248 5FTB ANP 4.74777
249 6C90 ADP 4.74777
250 1SVK ALF GDP 4.74777
251 1T8U UAP SGN IDS SGN 4.77941
252 1T8U A3P 4.77941
253 4R98 GNH 4.79705
254 1CLU DBG 4.81928
255 4YDS ATP 4.82456
256 1Y3A GDP 4.86322
257 2WIC GNP 4.86891
258 2JAQ DCP 4.87805
259 2OM2 GDP 4.92308
260 3CX8 GSP 4.92611
261 1UKZ ADP 4.92611
262 1XEX ATP 4.94506
263 3KTA AP5 4.94506
264 2ODE ALF GDP 4.96454
265 3EWA ANP 4.96894
266 4YMU ATP 5
267 2F9L GDP 5.02513
268 1MKY GDP 5.04451
269 2XTZ GSP 5.04451
270 5H7J GCP 5.04451
271 5H7K GDP 5.04451
272 2DPY ADP 5.04451
273 5XDR ADP 5.04451
274 2GK6 ADP 5.04451
275 3T1O GDP 5.05051
276 1BH2 GSP 5.07937
277 1Z83 AP5 5.10204
278 4BQS ADP 5.11364
279 4BQS K2Q 5.11364
280 2ZE7 DST 5.13834
281 2ZE7 AMP 5.13834
282 2V2V V12 5.16605
283 4JLV ADP 5.20446
284 1OE0 TTP 5.21739
285 5SZH GNP 5.22876
286 1OIV GDP 5.2356
287 1OIX GDP 5.2356
288 3T5G GDP 5.26316
289 1Z06 GNP 5.29101
290 4LJ9 ACP 5.30973
291 4KVA GTP 5.34125
292 4P4T GDP 5.34125
293 2WHX ADP 5.34125
294 5JCP GDP ALF 5.34125
295 2Q2Y ADP 5.34125
296 2Q2Y MKR 5.34125
297 4R43 GDP 5.34125
298 4Z0G 5GP 5.34125
299 3CNL GNP 5.34351
300 1I4D GDP 5.35714
301 1DAK ADP 5.35714
302 1DAK DPU 5.35714
303 3BD9 A3P 5.35714
304 3QXC ATP 5.3719
305 2B8T THM 5.38117
306 4D0N GDP 5.40541
307 5HPY GDP 5.40541
308 6BC0 GSP 5.40541
309 3LXR GDP 5.40541
310 6BCA GSP 5.40541
311 1E96 GTP 5.41872
312 3A1S GDP 5.42636
313 2CDN ADP 5.47264
314 1KY3 GDP 5.49451
315 1VHT BA3 5.50459
316 1D5C GDP 5.55556
317 3IIJ ADP 5.55556
318 1UJ2 ADP 5.55556
319 1UJ2 C5P 5.55556
320 3GJX GTP 5.55556
321 4KOT CE3 5.55556
322 4TTQ ATP 5.5814
323 1Z0F GDP 5.58659
324 5JCZ GDP 5.58659
325 2FH5 GTP 5.60748
326 5WRI A3P 5.625
327 5M04 GDP 5.63798
328 2VVG ADP 5.63798
329 5KSZ GCP 5.63798
330 3ZFD ANP 5.63798
331 4FRZ ADP 5.63798
332 1G41 ADP 5.63798
333 2ZJ5 ADP 5.63798
334 4LX0 BEF GDP 5.64972
335 4XTR ADP 5.65217
336 4XTR ATP 5.65217
337 4XVU ATP 5.65217
338 1PUJ GNP 5.67376
339 5E5U MLI 5.68182
340 1M7G AV2 5.6872
341 1M7G ADX 5.6872
342 1M7G ADP 5.6872
343 3NKV GNP 5.71429
344 2A5F GTP 5.71429
345 2YOH WMJ 5.71429
346 5K5Z ANP 5.73248
347 4FCW ADP 5.78778
348 1VG0 GDP 5.7971
349 1VG8 GNP 5.7971
350 3R96 AMP 5.85106
351 3R96 ACO 5.85106
352 1Z08 GNP 5.88235
353 4GBM A3P 5.88235
354 5MEX PAP 5.90062
355 5MEX SZZ 5.90062
356 4V0K GDP 5.91716
357 4KAX GTP 5.91716
358 5AK0 8V1 5.93472
359 2NCD ADP 5.93472
360 4PFO ADP 5.93472
361 1IHU AF3 5.93472
362 1IHU ADP 5.93472
363 1W5T ADP 5.93472
364 4ZDJ UTP 5.93472
365 1W5T ANP 5.93472
366 4W93 3L9 5.93472
367 5WRJ A3P 5.94059
368 2VZZ SCA 5.9633
369 1VKJ A3P 5.96491
370 2ZTS ADP 5.9761
371 5NM7 GLY 6.01504
372 1Q20 A3P 6.02007
373 1Q20 PLO 6.02007
374 3IO3 ADP 6.03448
375 3QVV 3QV 6.1017
376 3QVV A3P 6.1017
377 1YRB GDP 6.10687
378 2PZE ATP 6.11354
379 5NII FAD 6.14887
380 5UIV ADP 6.1674
381 3N5C GDP 6.17284
382 3PCR GTP 6.17284
383 4QRH 0O2 6.19048
384 1GHE ACO 6.21469
385 4J0Q GDP 6.23145
386 1X6V ADP 6.23145
387 5Z69 AGS 6.23145
388 2R42 FPS 6.23145
389 3WR7 COA 6.23145
390 2GQT FAD 6.34328
391 2X77 GDP 6.34921
392 5L3V GDP 6.35452
393 3SBD GNP 6.41711
394 3FIU POP 6.4257
395 2W2X GSP 6.45161
396 1NST A3P 6.46154
397 1VG9 GDP 6.48649
398 1VG1 GDP 6.48649
399 5DI3 GNP 6.48649
400 3AQ4 GDP 6.52174
401 1WDT GTP 6.52819
402 4IOK XPO 6.52819
403 4IOK ADP 6.52819
404 5TVJ COA 6.52819
405 5TVJ 7LF 6.52819
406 1G7C 5GP 6.55022
407 3BC1 GNP 6.66667
408 5VGR GDP 6.72854
409 2VWT PYR 6.74157
410 3ZS9 ADP ALF 6.77966
411 2WOJ ADP ALF 6.77966
412 4CVN ADP 6.80628
413 1WA5 GTP 6.81818
414 5Z2M GTP 6.81818
415 1AKY AP5 6.81818
416 5IRR GSP 6.81818
417 1NY5 ADP 6.82493
418 3FKQ ATP 6.82493
419 5MZN ADP 6.82493
420 6C0B MLI 6.82493
421 2O0J ADP 6.82493
422 3V2U ATP 6.82493
423 3BER AMP 6.82731
424 2WMO GTP 6.84211
425 3W5J GDP 6.86275
426 1ION ADP 6.99588
427 3BOS CDP 7.02479
428 1B7T ADP 7.05128
429 4KVX ACO 7.05128
430 1Z0J GTP 7.05882
431 4UXH T5A 7.06522
432 1W5F G2P 7.08215
433 1YVD GNP 7.10059
434 2XT3 ADP 7.12166
435 2OBM ADP 7.12166
436 3ZIA ADP 7.12166
437 3ZIA ATP 7.12166
438 5L3S GNP 7.12166
439 3WBD SIA SIA SIA SIA SIA SIA SIA 7.12166
440 1KK8 BEF ADP 7.14286
441 1GUA GNP 7.18563
442 3NHB ADP 7.18954
443 5U32 GDP 7.20339
444 4AVB ACO 7.20721
445 4ITR GDP 7.27848
446 5HCN GCP 7.27969
447 3Q9L ATP 7.30769
448 5J1S ATP 7.31707
449 2BEK ATP 7.393
450 1G7S GDP 7.40741
451 4GOJ GNP 7.40741
452 3U6B GDP 7.4184
453 4G5G GDP 7.4184
454 5JBQ GDP 7.4184
455 1D8T GDP 7.4184
456 4P3Y GDP 7.4184
457 3U6K GDP 7.4184
458 4PC3 GDP 7.4184
459 2BVN GNP 7.4184
460 4IHQ ADP 7.4184
461 5I0H ADP BEF 7.4184
462 3BFX A3P 7.43243
463 2WJG GDP 7.44681
464 2HCJ GDP 7.46269
465 4M9Q GNP 7.48899
466 2CHG ANP 7.52212
467 2BME GNP 7.52688
468 3SXN COA 7.58294
469 5IFS ADP 7.59494
470 2ZFZ ARG 7.59494
471 1UPT GTP 7.60234
472 2QQ0 ANP 7.6087
473 2QQ0 TMP 7.6087
474 2QQ0 ADP 7.6087
475 2QQ0 THM 7.6087
476 3LRE ADP 7.71513
477 4ZG4 VO4 ADP 7.71513
478 2CK3 ANP 7.72059
479 1W0J ADP 7.72059
480 1W0J ADP BEF 7.72059
481 2CK3 ADP 7.72059
482 1FZQ GDP 7.73481
483 1MR3 G3D 7.73481
484 4HDO GNP 7.76398
485 4HDQ GNP 7.76398
486 3X1Z GNP 7.78443
487 1GWN GTP 7.80488
488 5L3W GDP 7.84314
489 4TL6 ANP 7.90514
490 1RE0 GDP 7.92683
491 4R57 ACO 7.95455
492 4HAT GNP 8.01187
493 5UWQ GNP 8.01187
494 3M1I GTP 8.01187
495 5UWP GNP 8.01187
496 6CIT GNP 8.01187
497 5UWO GNP 8.01187
498 5DIF GNP 8.01187
499 5UWI GNP 8.01187
500 5UWU GNP 8.01187
501 5UWR GNP 8.01187
502 5UWW GNP 8.01187
503 5DHF GNP 8.01187
504 5UWS GNP 8.01187
505 5UWH GNP 8.01187
506 5UWT GNP 8.01187
507 3WYF GTP 8.01187
508 6A20 ADP 8.01187
509 2GKS ADP 8.01187
510 5UWJ GNP 8.01187
511 5DI9 GNP 8.01187
512 5ZBR ANP 8.01187
513 2FAH GDP 8.01187
514 2QZ4 ADP 8.01527
515 1ZJ6 G3D 8.02139
516 2JEV NHQ 8.04598
517 2B4D COA 8.18713
518 3KJI ADP 8.26772
519 1KK1 GNP 8.30861
520 4YC7 GNP 8.30861
521 4LPS GDP 8.30861
522 5BYK A3P 8.30861
523 5BYK OAQ 8.30861
524 2I4I AMP 8.30861
525 3RLF ANP 8.30861
526 2FXU BID 8.30861
527 2CJW GDP 8.33333
528 3ZQ6 ADP ALF 8.33333
529 1YZG GDP 8.37989
530 2WJH GDP 8.43373
531 2WJH FLC 8.43373
532 3A4M ADP 8.46154
533 1R4A GNP 8.48485
534 1W7J ADP BEF 8.60927
535 3KUD GDP 8.64198
536 1M7B GTP 8.69565
537 5TIV A3P 8.69565
538 5H67 ATP 8.75
539 1CR1 TTP 8.78378
540 1TU3 GNP 8.86076
541 3Q85 GNP 8.87574
542 4XOI GTP 8.88889
543 1HE1 GDP 8.88889
544 3AB3 GDP 8.94309
545 3E5H GNP 8.98876
546 3FYH ADP 9.00621
547 4R2I ANP 9.04762
548 2PZ8 APC 9.15493
549 1JI0 ATP 9.16667
550 2HT6 GDP 9.1954
551 4OI4 ATP 9.19881
552 2GMV UN8 9.19881
553 1NHX PEP 9.19881
554 1NHX FTB 9.19881
555 2GMV PEP 9.19881
556 3FWY ADP 9.23567
557 1Y63 ADP 9.23913
558 2C5L GTP 9.24856
559 5E95 GDP 9.27835
560 4WOP CTP 9.33333
561 1OFH ADP 9.35484
562 4K81 GTP 9.35672
563 2EFE GNH 9.39227
564 2OZE AGS 9.39597
565 2VB6 ADP BEF 9.39597
566 1G16 GDP 9.41177
567 2EW1 GNP 9.45274
568 1F2U ATP 9.45946
569 4DCT GDP 9.49555
570 1BO4 COA 9.52381
571 4U5X GNP 9.55056
572 1S8F GDP 9.60452
573 3Q72 GNP 9.63855
574 2UZI GTP 9.63855
575 3TMK T5A 9.72222
576 1NN5 ANP 9.76744
577 1NN5 2DT 9.76744
578 3GJ8 GDP 9.78261
579 5W75 GDP 9.79228
580 5W75 SUC 9.79228
581 2IS6 ADP 9.79228
582 4AUT FAD 9.79228
583 4DID GDP 9.86842
584 5KSP GDP 10
585 2QN6 GDP 10.089
586 1KSH GDP 10.089
587 4RD0 GDP 10.089
588 1YTM ATP 10.089
589 2OFW ADX 10.0962
590 1Z2A GDP 10.119
591 3T12 GDP ALF 10.2941
592 1S9D GDP 10.3448
593 4V03 ADP 10.5058
594 1G3Q ADP 10.5485
595 4BAS GNP 10.5528
596 4E03 ADP 10.6796
597 3DOE GTP 10.6825
598 4A4Z ANP 10.6825
599 3BFV ADP 10.7011
600 4KVG GTP 10.7143
601 1HTW ADP 10.7595
602 3PQC GDP 10.7692
603 1XX6 ADP 10.9948
604 3GJ7 GDP 11.2245
605 3B7G ANP 11.3043
606 4HUT ATP 11.5183
607 5LB3 ADP 11.5727
608 2W83 GTP 11.6883
609 2PEZ DAT 11.7318
610 2PEZ GGZ 11.7318
611 1FP6 ADP 11.7647
612 1FQJ GDP 11.9048
613 1S3G AP5 11.9816
614 1CS4 GSP 12
615 3QF7 ANP 12.1662
616 5BQ5 ADP BEF 12.1693
617 2QTV GNP 12.2449
618 4WZA ACP 12.3188
619 4WZA ADP 12.3188
620 3T34 GDP 12.4629
621 3CV2 OXL 12.4629
622 3UIE ANP 12.5
623 3B5J 12D 12.7572
624 2OG2 MLI 12.7596
625 5TB5 GDP 12.973
626 5TAR GDP 12.973
627 4C4P GNP 13.0841
628 1ZUI SKM 13.0952
629 4TMK T5A 13.1455
630 3QBT GNP 13.2184
631 4LHW GNP 13.2184
632 3TNF GNP 13.2184
633 2HF9 GSP 13.2743
634 3CPJ GDP 13.3531
635 2BCG GDP 13.3531
636 3AB4 THR 13.3531
637 1JJV ATP 13.5922
638 5LLB 6YZ 13.6882
639 5OCG GNP 13.7566
640 1NRJ GTP 14.2202
641 3B9Q MLI 14.2384
642 4ZI2 GNP 14.2857
643 3WYG GTP 14.4737
644 5EE5 GTP 14.5401
645 4XSH GSP 14.6119
646 5L3R GCP 14.6758
647 1E2K TMC 14.8036
648 3DEF GDP 14.8855
649 2A9K GDP 14.9733
650 3H86 AP5 15.1042
651 2V7Q ATP 15.1515
652 2V7Q ADP 15.1515
653 6CRK GDP 15.493
654 3H4S ADP 15.5556
655 6BCB GSP 15.7534
656 5O3Q CMP 15.8333
657 1UAD GNP 16
658 4BFW ZVW 16.3522
659 1ZD9 GDP 16.4894
660 1U8Z GDP 16.6667
661 1LVG ADP 16.6667
662 3E70 GDP 16.7683
663 5UQW GDP 16.9312
664 2RGX AP5 17.4757
665 4RZ3 ADP 17.9661
666 1O3Y GTP 18.0723
667 1J2J GTP 18.0723
668 2J59 GTP 18.0723
669 2F3R G5P 18.8406
670 5O2T GSP 18.9349
671 3VMF GTP 19.8813
672 3WXM GTP 19.8813
673 4D0G GTP 20.2899
674 1L3I SAH 20.3125
675 3CH5 GDP 21.1538
676 1ZC3 GNP 22.2857
677 2QG6 NMN 23.1156
678 5OEC GDP 23.4973
679 1RJ9 GCP 23.6842
680 3DDC GNP 23.9264
681 2IYL GDP 25.3521
682 6CS8 F9Y 26.0726
683 5UPK GNP 27.0833
684 5XKT GNP 31.5
685 2IL4 COA 32.0388
686 1GXU 2HP 32.967
687 1Z0K GTP 33.3333
688 4HI0 GDP 35.1759
Pocket No.: 2; Query (leader) PDB : 4LC1; Ligand: GDP; Similar sites found with APoc: 21
This union binding pocket(no: 2) in the query (biounit: 4lc1.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5CUQ NSC 1.87266
2 4DPL NAP 2.07715
3 1Q19 SSC 2.67062
4 3KC1 2T6 2.67062
5 1Q19 APC 2.67062
6 1V5F TPP 3.2641
7 1V5F FAD 3.2641
8 1I1D 16G 3.72671
9 4D42 W0I 4.25532
10 4D42 NAP 4.25532
11 5ULP KB1 4.85075
12 1WRA PC 5.34125
13 1M5B BN1 6.08365
14 3TE4 ACO 6.51163
15 1MVQ MMA 6.77966
16 5L3S G 7.12166
17 2JK0 ASP 7.38462
18 2V5K OXM 8.36237
19 4K7O EKZ 8.92857
20 4B5W PYR 9.375
21 2ZX2 RAM 9.74359
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