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Receptor
PDB id Resolution Class Description Source Keywords
4JNA 2 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE DEPH COMPLEX WITH DIMETHYL-FK228 CHROMOBACTERIUM VIOLACEUM DISULFIDE BOND FORMATION FK228 DEPSIPEPTIDE FAD-DEPENDENTOXIDOREDUCTASE OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COM
Ref.: THE STRUCTURAL BASIS OF AN NADP+-INDEPENDENT DITHIO IN FK228 BIOSYNTHESIS. SCI REP V. 4 4145 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
1KC DVA 060 DBU VAL I:1;
H:1;
Valid;
Valid;
none;
none;
submit data
574.808 n/a S(CCC...
GOL B:405;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
FAD A:401;
B:401;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
CL B:402;
A:402;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
EDO A:403;
B:403;
A:404;
B:404;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
PO4 A:405;
Invalid;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4JNA 2 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE DEPH COMPLEX WITH DIMETHYL-FK228 CHROMOBACTERIUM VIOLACEUM DISULFIDE BOND FORMATION FK228 DEPSIPEPTIDE FAD-DEPENDENTOXIDOREDUCTASE OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COM
Ref.: THE STRUCTURAL BASIS OF AN NADP+-INDEPENDENT DITHIO IN FK228 BIOSYNTHESIS. SCI REP V. 4 4145 2014
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4JN9 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 4NTE - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 4JNA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4JN9 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 4NTE - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 4JNA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4JN9 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 4NTE - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 4JNA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 1KC DVA 060 DBU VAL; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 1KC DVA 060 DBU VAL 1 1
Ligand no: 2; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4JNA; Ligand: FAD; Similar sites found with APoc: 931
This union binding pocket(no: 1) in the query (biounit: 4jna.bio2) has 50 residues
No: Leader PDB Ligand Sequence Similarity
1 5AHO TLA None
2 1NYT NAP 0.738007
3 5YF1 SFG 0.882353
4 3U31 NAD 1.03448
5 2PX8 SAH 1.11524
6 1CDO NAD 1.17647
7 4XDY NAI 1.18343
8 5JJR SAH 1.34529
9 1ZQ9 SAM 1.40351
10 1BW9 NAD 1.47059
11 1C1X NAD 1.47059
12 1BXG NAD 1.47059
13 6C8R SAH 1.47059
14 4V3C C 1.47059
15 1SB8 UD2 1.47059
16 1SB8 NAD 1.47059
17 1CF2 NAP 1.48368
18 4ZRN UPG 1.60256
19 4ZRN NAD 1.60256
20 3N9R TD3 1.62866
21 2WET FAD 1.76471
22 1X87 NAD 1.76471
23 1BXK NAD 1.76471
24 5MPT SAH 1.76471
25 5EVY FAD 1.76471
26 1KOL NAD 1.76471
27 1RJD SAM 1.76471
28 1P0F NAP 1.76471
29 3KC1 2T6 1.78042
30 2WA2 SAM 1.81159
31 2PT9 S4M 1.86916
32 2PT9 2MH 1.86916
33 4FWE FAD 1.88442
34 2YY7 NAD 1.92308
35 3KO8 NAD 1.92308
36 4GUS FAD 1.93299
37 4GUT FAD 1.93299
38 1GUZ NAD 1.93548
39 1EQ2 NAP 1.93548
40 2PWY SAH 1.93798
41 4BUZ NAD 2.03252
42 1YC5 NCA 2.03252
43 3GMB FAD 2.05882
44 4BV6 FAD 2.05882
45 2QA1 FAD 2.05882
46 2YG3 FAD 2.05882
47 5HXI FAD 2.05882
48 5HXI 5HN 2.05882
49 2IZ1 ATR 2.05882
50 1O0S NAI 2.05882
51 5LD5 NAD 2.05882
52 3DMH SAM 2.05882
53 2YYY NAP 2.05882
54 5HJM MTA 2.05882
55 1YS4 NAP 2.05882
56 6HL7 CP 2.05882
57 4LOC BTN 2.05882
58 1WVG APR 2.05882
59 3DMH GMP 2.05882
60 1QPG MAP 2.05882
61 3A1I UNU 2.05882
62 1R6D NAD 2.07715
63 1R6D DAU 2.07715
64 4DR9 BB2 2.08333
65 3BXO SAM 2.09205
66 5NUF NAD 2.10843
67 5NUE NAD 2.10843
68 4PLT NAI 2.1148
69 4PLT OXM 2.1148
70 2I7C AAT 2.12014
71 6BWL NAD 2.13415
72 5BSH PRO 2.16606
73 3NK7 SAM 2.16606
74 2O07 MTA 2.30263
75 2O07 SPD 2.30263
76 4YUW S4M 2.30263
77 4YUW 4JU 2.30263
78 1RRC ADP 2.32558
79 4NBW NAD 2.33463
80 5JWC FAD 2.35294
81 5GSN FAD 2.35294
82 5GSN NAP 2.35294
83 3NYC FAD 2.35294
84 3NYC IAR 2.35294
85 5GSN MMZ 2.35294
86 2D2I NAP 2.35294
87 4LWP SAH 2.35294
88 2O4C NAD 2.35294
89 3H9E NAD 2.35294
90 5DWQ SFG 2.35294
91 4XYB NDP 2.35294
92 4KVL PLM 2.35294
93 1WPQ NAD 2.35294
94 2EJU SAH 2.35294
95 5DX1 SFG 2.35294
96 4KRG SAH 2.35294
97 5DXA SFG 2.35294
98 1KEV NDP 2.35294
99 4OOE NDP 2.35294
100 5KOK SAH 2.35294
101 5DX8 SFG 2.35294
102 1LLU NAD 2.35294
103 3B20 NAD 2.35988
104 3B1J NAD 2.35988
105 3FJG 3PG 2.39044
106 1FIW PBZ 2.41379
107 1LDM NAD 2.43161
108 1VAY AZA 2.43902
109 5GZ6 NDP 2.45399
110 5GZ6 7C3 2.45399
111 1QAN SAH 2.45902
112 1EDO NAP 2.45902
113 5LQ8 GB 2.48227
114 4D52 GXL 2.53968
115 1P77 ATR 2.57353
116 5M58 SAH 2.6087
117 1O6Z NAD 2.64026
118 3GD4 FAD 2.64706
119 3GD4 NAD 2.64706
120 1QO8 FAD 2.64706
121 4K5S FAD 2.64706
122 4K5S PM0 2.64706
123 1X14 NAD 2.64706
124 4MIG G3F 2.64706
125 1QCI ADE 2.64706
126 2QES ADE 2.64706
127 3PT9 SAH 2.64706
128 4JJF FE9 2.64706
129 2NAD NAD 2.64706
130 1KJ8 GAR 2.64706
131 2GSD NAD 2.64706
132 1YP4 ADP 2.64706
133 4JJF N2I 2.64706
134 5A1T NAI 2.64706
135 1Y8Q ATP 2.64706
136 5A1T OXM 2.64706
137 2X2M X2M 2.64706
138 1RM4 NDP 2.67062
139 4L8V NAP 2.67062
140 4GLL NAD 2.67062
141 6DUB SAH 2.7027
142 1HDG NAD 2.71084
143 2Q8M AMP 2.71084
144 3HVJ 705 2.71493
145 4OBW SAM 2.72374
146 1VL0 NAI 2.73973
147 2HJR APR 2.7439
148 1SOW NAD 2.7439
149 1OMO NAD 2.79503
150 4I7E PEP 2.82132
151 2F1K NAP 2.86738
152 1IM8 SAI 2.86885
153 5KVA SAM 2.8777
154 1GV0 NAD 2.90323
155 2IVD FAD 2.94118
156 2HHP FLC 2.94118
157 2RGO FAD 2.94118
158 4M37 SAH 2.94118
159 1L7E NAI 2.94118
160 4RQU NAD 2.94118
161 5CAE COA 2.94118
162 5X62 SAH 2.94118
163 1QMG APX 2.94118
164 3V1U NAD 2.94118
165 1ORR NAD 2.94118
166 3H2B SAH 2.94118
167 2Q28 ADP 2.94118
168 5D2H AKG 2.94118
169 5EIN NAP 2.94118
170 1RJW ETF 2.94985
171 3WBF NAP 2.95082
172 3WBF API 2.95082
173 1NM5 NAD 2.95567
174 1DLJ NAI 2.98507
175 1Z82 NDP 2.98507
176 1DLJ UGA 2.98507
177 5LOG SAH 3.00429
178 3FW3 ETS 3.00752
179 5GT9 NAP 3.04183
180 2B9W FAD 3.06604
181 1E6W NAD 3.07692
182 1ZGA SAH 3.08123
183 5OCM NAP 3.09278
184 5UAV TFB 3.10559
185 5UAV NDP 3.10559
186 6C4T NA7 3.11111
187 3VGL BGC 3.11526
188 1KPG SAH 3.13589
189 5OJ7 AR6 3.14685
190 2RGH FAD 3.15236
191 1S7G APR 3.16206
192 1S7G NAD 3.16206
193 4OVZ P85 3.16456
194 1RTF BEN 3.1746
195 5X20 NAD 3.20513
196 5IFK HPA 3.20513
197 3G5S FAD 3.23529
198 3T31 FAD 3.23529
199 3T31 DCQ 3.23529
200 3GDN HBX 3.23529
201 3GDN FAD 3.23529
202 1E1M NAP 3.23529
203 1E1M FAD 3.23529
204 5WGR FAD 3.23529
205 2C7G FAD 3.23529
206 3K5I AIR 3.23529
207 2C7G ODP 3.23529
208 3A06 NDP 3.23529
209 4XDZ NDP 3.23529
210 6C4M NAP 3.23529
211 2B4R AES 3.23529
212 5E4R NAP 3.23529
213 1VJT NAD 3.23529
214 2B4R NAD 3.23529
215 2VHW NAI 3.23529
216 3WLE NAD 3.23529
217 1G55 SAH 3.23529
218 2JK0 ASP 3.23529
219 1OC2 NAD 3.23529
220 1OC2 TDX 3.23529
221 2FJK 13P 3.23529
222 3S1S SAH 3.23529
223 1UXG NAD 3.23625
224 1UXG FUM 3.23625
225 3OFK SAH 3.24074
226 1YRO UDP 3.25203
227 6BSW UDP 3.25444
228 3A4T SFG 3.28467
229 4MDH NAD 3.29341
230 4KOA NDP 3.3033
231 2DT5 NAD 3.31754
232 2VYN NAD 3.32326
233 1Q9I TEO 3.3275
234 1Q9I FAD 3.3275
235 1GAD NAD 3.33333
236 3NOJ PYR 3.36134
237 1ZBQ NAD 3.36391
238 2GZM DGL 3.37079
239 3C3Y SAH 3.37553
240 1H5Q NAP 3.39623
241 3LCC SAH 3.40426
242 1GQ2 NAP 3.42342
243 6ECT SAM 3.42679
244 2OOR NAD 3.44828
245 1DL5 SAH 3.47003
246 1TPY SAH 3.48432
247 1KPH SAH 3.48432
248 4IWN GEK 3.49345
249 5OVK NDP 3.51562
250 3GU3 SAH 3.52113
251 1NV8 MEQ 3.52113
252 1NV8 SAM 3.52113
253 5E9W SAH 3.52564
254 2AQJ FAD 3.52941
255 2AQJ TRP 3.52941
256 2E5V FAD 3.52941
257 2RGJ FAD 3.52941
258 5NA1 FAD 3.52941
259 5UAO FAD 3.52941
260 4B63 ORN 3.52941
261 4B63 FAD 3.52941
262 4B63 NAP 3.52941
263 5G3U FDA 3.52941
264 5G3U ITW 3.52941
265 6C4N NAP 3.52941
266 4C4A SAH 3.52941
267 1HKU NAD 3.52941
268 6D6Y SAH 3.52941
269 1X7D NAD 3.52941
270 1E3I CXF 3.52941
271 3ULK NDP 3.52941
272 1ZH8 NAP 3.52941
273 1P31 EPU 3.52941
274 3OND ADN 3.52941
275 3OND NAD 3.52941
276 4OM8 NAD 3.55987
277 4GKV NAD 3.57143
278 4Z0H NAD 3.59281
279 6FDF SAH 3.59281
280 9LDT NAD 3.61446
281 9LDB NAD 3.61446
282 3FUU ADN 3.69004
283 4YAC NAI 3.7037
284 6B74 BEN 3.7037
285 1JQ3 AAT 3.71622
286 3ZG6 APR 3.71622
287 2VT3 ATP 3.72093
288 5ULP KB1 3.73134
289 5K4W NAI 3.73832
290 1GZ6 NAI 3.76176
291 1NW5 SAM 3.76176
292 2AG8 NAP 3.80228
293 1XHC FAD 3.82353
294 5MZI FAD 3.82353
295 5MZI FYK 3.82353
296 5Y77 FAD 3.82353
297 4U8P UDP 3.82353
298 4U8P FDA 3.82353
299 4RSL FAD 3.82353
300 5UR0 NAD 3.82353
301 5Z21 NAI 3.82353
302 6DNT NAD 3.82353
303 2EFJ SAH 3.82353
304 6CAM BGC 3.82353
305 1NPD NAD 3.82353
306 5X9D 80F 3.82353
307 2X6T NAP 3.82353
308 1VI2 NAD 3.82353
309 6F9Q NAD 3.82353
310 5WS9 AMP 3.82353
311 2FWP CIT 3.82514
312 2FWP ICR 3.82514
313 1E3W NAD 3.83142
314 1LUA NAP 3.83275
315 1ZK7 FAD 3.85439
316 1L5Y BEF 3.87097
317 3GCZ SAM 3.90071
318 1I9G SAM 3.92857
319 1XTP SAI 3.93701
320 4FN4 NAD 3.93701
321 3R7F CP 3.94737
322 3SJ7 NDP 3.96825
323 5ZW3 SAH 4
324 2EWM NAD 4.01606
325 3GFS FMN 4.02299
326 1F3L SAH 4.04984
327 5U5G NAP 4.0678
328 2WD7 NAP 4.10448
329 3RNM FAD 4.11765
330 5J5Z FAD 4.11765
331 2F5Z FAD 4.11765
332 4JDR FAD 4.11765
333 2GMH FAD 4.11765
334 1YQZ FAD 4.11765
335 1H82 FAD 4.11765
336 1H82 GZZ 4.11765
337 5X68 FAD 4.11765
338 4MO2 FAD 4.11765
339 4MO2 FDA 4.11765
340 4KRI SAH 4.11765
341 3ABI NAD 4.11765
342 5ERG SAM 4.11765
343 1D1T NAD 4.11765
344 5FWA J7C 4.11765
345 1VKO NAD 4.11765
346 4D86 ADP 4.11765
347 1MV8 NAD 4.11765
348 1YKF NAP 4.11765
349 2W47 UNF 4.16667
350 5AOV NAP 4.16667
351 2HMT NAI 4.16667
352 2DBZ NAP 4.19162
353 3VPH NAD 4.19355
354 3VPH OXM 4.19355
355 1PZG A3D 4.22961
356 2I3G NAP 4.26136
357 5N2I NAP 4.31034
358 2NXE SAM 4.33071
359 2PV7 NAD 4.36242
360 6GFK SAH 4.38247
361 1A5Z NAD 4.38871
362 1P4V GLY 4.40678
363 1C0I FAD 4.40771
364 1C0I BE2 4.40771
365 1V59 NAD 4.41176
366 1V59 FAD 4.41176
367 3WGT FAD 4.41176
368 3WGT QSC 4.41176
369 4IV9 FAD 4.41176
370 3X0D SAH 4.41176
371 3GF4 UPG 4.41176
372 3GF4 FAD 4.41176
373 2BZG SAH 4.41176
374 5N5D SAM 4.42478
375 5TC4 NAD 4.43038
376 1H5T TYD 4.43686
377 5EES NAP 4.45344
378 3NUG NAD 4.45344
379 3FWY ADP 4.4586
380 4L8F MTX 4.48718
381 5BW4 SAM 4.49438
382 4D3F NAP 4.51613
383 1VCE SAH 4.5283
384 1WNG SAH 4.5283
385 3OZ2 FAD 4.53401
386 1B8U NAD 4.55927
387 3DXY SAM 4.58716
388 2CVQ NDP 4.58716
389 1U7T NAD 4.5977
390 5ZBC FAD 4.65632
391 5BVA FAD 4.70588
392 5KOX FAD 4.70588
393 5KOX RFP 4.70588
394 2R4J FAD 4.70588
395 2R4J 13P 4.70588
396 1F8G NAD 4.70588
397 3X0V FAD 4.70588
398 3DAG FEG 4.70588
399 1LJ8 NAD 4.70588
400 1KYZ SAH 4.70588
401 1M2W NAD 4.70588
402 3HIY UTP 4.70588
403 3HJ1 UTP 4.70588
404 2PTM CMP 4.70588
405 1SAY PYR 4.70914
406 2ZIF SAM 4.7138
407 2CHT TSA 4.72441
408 1JA9 NDP 4.74453
409 4ZCC NAI 4.7619
410 4ZCC FAD 4.7619
411 1NVM NAD 4.80769
412 3LL5 IP8 4.81928
413 1O5I NAD 4.81928
414 1CER NAD 4.83384
415 4REP FAD 4.84848
416 1HYH NAD 4.85437
417 2QQF A1R 4.87013
418 2OD9 A1R NCA 4.87013
419 3QV1 NAD 4.87805
420 1D4O NAP 4.8913
421 1NXJ TLA 4.91803
422 1HDR NAD 4.91803
423 3DUW SAH 4.93274
424 3GDH SAH 4.97925
425 2NVK FAD 5
426 1FEC FAD 5
427 1Q1R FAD 5
428 1GPE FAD 5
429 4TXI FAD 5
430 2NVK NAP 5
431 1COY AND 5
432 1COY FAD 5
433 3MAG SAH 5
434 3MCT SAH 5
435 1GPM CIT 5
436 4C2G ALA ALA ALA ALA 5
437 4R6W SAH 5
438 2ZJ1 NAD 5
439 2FLI DX5 5
440 2ZJ1 ARJ 5
441 1GR0 NAD 5
442 5E72 SAM 5
443 1EZ4 NAD 5.03145
444 2BGM NAJ 5.03597
445 5MGZ SAH 5.08475
446 3UC5 ATP 5.09554
447 4BQS K2Q 5.11364
448 6A0S HSE 5.12048
449 6A0S NDP 5.12048
450 3I53 SAH 5.12048
451 1JAY NAP 5.18868
452 1M2K APR 5.22088
453 3SQP FAD 5.29412
454 4M52 FAD 5.29412
455 4M52 M52 5.29412
456 2A8X FAD 5.29412
457 2Z3Y F2N 5.29412
458 1PN0 FAD 5.29412
459 1PN0 IPH 5.29412
460 5AYV NAP 5.29412
461 2DKH 3HB 5.29412
462 2DKH FAD 5.29412
463 4MOP 2H5 5.29412
464 1DJN ADP 5.29412
465 2IXB NAD 5.29412
466 6CEP NAD 5.29412
467 6CEP OXM 5.29412
468 2IXB A2G 5.29412
469 5AYV KPL 5.29412
470 4E13 NAD 5.30035
471 4YSX FAD 5.31915
472 1LTH NAD 5.32915
473 4BVA NDP 5.37313
474 2DT9 THR 5.38922
475 4YMH SAH 5.41667
476 1WP4 NDP 5.53633
477 2CVZ NDP 5.53633
478 4YAG NAI 5.53633
479 6GAR FAD 5.58824
480 5OC1 FAD 5.58824
481 3QVP FAD 5.58824
482 4KIB SAH 5.58824
483 3C6K SPD 5.58824
484 3MQ2 SAH 5.58824
485 3C6K MTA 5.58824
486 5M67 3D1 5.58824
487 2I6A 5I5 5.58824
488 5M67 NAD 5.58824
489 5M67 ADE 5.58824
490 2A92 NAI 5.60748
491 1YJQ NAP 5.61056
492 1N2X SAM 5.64784
493 2G5C NAD 5.69395
494 5CK5 GDP 5.6962
495 1VM6 NAD 5.70175
496 5KKA 6V0 5.76923
497 5X2N ALA 5.77778
498 4D79 ATP 5.7971
499 2AOT SAH 5.82192
500 1JQD SAH 5.82192
501 3EGI ADP 5.82524
502 4NBT NAD 5.83333
503 5BUK FAD 5.88235
504 5TWB FAD 5.88235
505 2HQM FAD 5.88235
506 4CNK FAD 5.88235
507 1GTE FAD 5.88235
508 1REO FAD 5.88235
509 5ZYN FAD 5.88235
510 4Y9D NAI 5.88235
511 2IID PHE 5.88235
512 2IID FAD 5.88235
513 3QJ4 FAD 5.88235
514 4RPL FAD 5.88235
515 4RPL 3UC 5.88235
516 5TS5 FAD 5.88235
517 1O94 ADP 5.88235
518 1ELI PYC 5.88235
519 4DCM SAM 5.88235
520 4WS6 WBU 5.88235
521 3HDY FAD 5.88235
522 3HDY FDA 5.88235
523 3HDY GDU 5.88235
524 1XDS SAM 5.88235
525 1L1Q 9DA 5.91398
526 1RZM E4P 5.91716
527 4QTU SAM 5.92593
528 1JG3 ADN 5.95745
529 3UKR CKH 5.96026
530 1T5B FMN 5.97015
531 4PLG NAI 5.98802
532 4PLG OXM 5.98802
533 1JNR FAD 6
534 3Q3C NAD 6.02007
535 3RKR NAP 6.10687
536 1S17 GNR 6.11111
537 4YCA NDP 6.12245
538 6B92 SAH 6.12245
539 2NPX NAD 6.17647
540 2NPX FAD 6.17647
541 4Z24 FAD 6.17647
542 4HA6 FAD 6.17647
543 2Y6Q I7T 6.17647
544 2Y6Q FAD 6.17647
545 2JB2 PHE 6.17647
546 2JB2 FAD 6.17647
547 4C3Y FAD 6.17647
548 5F8F SFG 6.17647
549 3V1Y NAD 6.17647
550 4ZGS NAD 6.17647
551 4C3Y ANB 6.17647
552 3CIF NAD 6.17647
553 3SSO SAH 6.17647
554 2Q1S NAI 6.17647
555 4DSG FAD 6.17647
556 4DSG UDP 6.17647
557 3WMX NAD 6.17647
558 3CIF G3H 6.17647
559 5XNC MTA 6.17647
560 3LU1 NAD 6.17647
561 6A3J NAI 6.17647
562 3HQP OXL 6.17647
563 4RD0 GDP 6.17647
564 5YAP NAI 6.17647
565 5YAP 8S0 6.17647
566 1UAY ADN 6.19835
567 1FK8 NAD 6.22568
568 2HNK SAH 6.27615
569 3QWI NAP 6.2963
570 3BAZ NAP 6.30631
571 1PVC ILE SER GLU VAL 6.31229
572 1LDN NAD 6.32911
573 2PZM UDP 6.36364
574 2PZM NAD 6.36364
575 3CBG SAH 6.46552
576 3E1T FAD 6.47059
577 5BRT CH9 6.47059
578 5BRT FAD 6.47059
579 5HSA FAS 6.47059
580 6H3O FAD 6.47059
581 5TUF TDC 6.47059
582 5TUF FAD 6.47059
583 5TUK FAD 6.47059
584 5Z20 NAI 6.47059
585 1J0X NAD 6.47059
586 1GY8 NAD 6.47059
587 2JJQ SAH 6.47059
588 4EUE NAI 6.47059
589 4D7E FAD 6.47059
590 4CQM NAP 6.47059
591 5U19 827 6.47059
592 5U19 SAH 6.47059
593 3B9O FMN 6.47059
594 4MCC 21X 6.50407
595 3LKZ SFG 6.54206
596 1RYI GOA 6.5445
597 1RYI FAD 6.5445
598 3KB6 NAD 6.58683
599 4RDH AMP 6.59722
600 4RDI ATP 6.59722
601 2Q1W NAD 6.60661
602 5JE8 NAD 6.62252
603 3GGO NAI 6.6879
604 3GGO ENO 6.6879
605 1J5P NAD 6.71937
606 4YRY FAD 6.76471
607 4YRY NAD 6.76471
608 3NKS FAD 6.76471
609 3K7M FAD 6.76471
610 3AYI HCI 6.76471
611 3AYI FAD 6.76471
612 5EOW FAD 6.76471
613 6F97 FAD 6.76471
614 3S5W NAP 6.76471
615 3ZNN FAD 6.76471
616 3ZNN 4WL 6.76471
617 3S5W FAD 6.76471
618 5T63 ALA ALA ALA ALA 6.76471
619 2HIM ASN 6.76471
620 2WHX ADP 6.76471
621 4ZVV GN0 6.76471
622 4J1Q NDP 6.76471
623 5GM1 SAH 6.76471
624 4ZVV NAD 6.76471
625 1SC3 MLI 6.81818
626 5XVH NAP 6.86275
627 3GEG NAD 6.88259
628 4CJX NAP 6.89655
629 6ECU SAH 6.96203
630 5Z75 NAD 7.03364
631 4EMI NAD 7.05882
632 4EMI FAD 7.05882
633 3KLJ FAD 7.05882
634 4J36 1HR 7.05882
635 4J36 FAD 7.05882
636 1I8T FAD 7.05882
637 1SC6 NAD 7.05882
638 3P2E SAH 7.05882
639 2VVT DGL 7.24138
640 1EBF NAD 7.26257
641 2GCG NDP 7.27273
642 6AA8 NAD 7.28477
643 2NU8 COA 7.29167
644 3JQA NAP 7.29167
645 5JCJ NAP 7.29167
646 3JQ8 NAP 7.29167
647 5JDI NAP 7.29167
648 5K6A NAP 7.29167
649 3JQ9 NAP 7.29167
650 3JQ7 NAP 7.29167
651 3JQF NAP 7.29167
652 4CM9 NAP 7.29167
653 4CLR NAP 7.29167
654 3BMO NAP 7.29167
655 3BMQ NAP 7.29167
656 5JDC NAP 7.29167
657 3BMN NAP 7.29167
658 4CMI NAP 7.29167
659 3JQB NAP 7.29167
660 4CM4 NAP 7.29167
661 4CM8 NAP 7.29167
662 3JQG NAP 7.29167
663 1NVT NAP 7.31707
664 5N6C NAD 7.33333
665 4OPC FDA 7.35294
666 4OPC PGT 7.35294
667 4USQ FAD 7.35294
668 5DNK SAH 7.35294
669 2VVL FAD 7.35294
670 2VVM FAD 7.35294
671 4YNU FAD 7.35294
672 1D4D FAD 7.35294
673 4YNU LGC 7.35294
674 1W8D NAP 7.35294
675 1KEW NAD 7.35294
676 3AXB PRO 7.36607
677 3AXB FAD 7.36607
678 5OJL TXP 7.38255
679 4CPB GAL CN8 7.43802
680 3L4S NAD 7.44048
681 3L4S 3PG 7.44048
682 4POO SAM 7.5
683 1DSS NAD 7.50751
684 6BII NAP 7.50751
685 4E5N NAD 7.57576
686 1VMK GUN 7.58123
687 5I39 FAD 7.59804
688 5JCA NDP 7.64706
689 5JCA FAD 7.64706
690 6F7L FAD 7.64706
691 3QOX SAH 7.64706
692 5THQ NDP 7.72059
693 5T9E NAP 7.74908
694 1EJ0 SAM 7.77778
695 1E6E FAD 7.8125
696 3MB5 SAM 7.84314
697 1DIG NAP 7.84314
698 4COV GLA GAL 7.86517
699 1PJS NAD 7.87746
700 5E1M SAH 7.88382
701 1R18 SAH 7.92952
702 3B1F NAD 7.93103
703 5TTJ FAD 7.94118
704 1RSG FAD 7.94118
705 2XVE FAD 7.94118
706 2XVF FAD 7.94118
707 2EG5 SAH 7.94118
708 1Z45 NAD 7.94118
709 4XQC 13D 7.94118
710 4XQC NAD 7.94118
711 4N49 SAM 7.94118
712 5OD2 5ID 7.94118
713 1G60 SAM 7.94118
714 2CDC XYP 7.94118
715 4NBU NAI 8
716 6APL C5P 8.02139
717 3BGD SAH 8.07692
718 1J49 NAD 8.10811
719 5Y8L NAD 8.13559
720 5Y8L HUI 8.13559
721 2FK8 SAM 8.1761
722 3T7S SAM 8.20895
723 6FHO FAD 8.23529
724 1YKJ PHB 8.23529
725 1YKJ FAD 8.23529
726 1GZ4 ATP 8.23529
727 1YQD NAP 8.23529
728 2XYQ SAH 8.27586
729 4NEC SAH 8.33333
730 1R37 NAD 8.35735
731 2EV9 NAP 8.36502
732 2EV9 SKM 8.36502
733 2AHR NAP 8.49421
734 5OFW 9TW 8.52018
735 1MUU NAD 8.52941
736 1WDK NAD 8.52941
737 1V8B NAD 8.52941
738 1H2B NAJ 8.52941
739 4D5G FAD 8.52941
740 2IV3 UDP 8.52941
741 1R6N 434 8.53081
742 1M0S CIT 8.6758
743 5L95 AMP 8.75
744 3ORF NAD 8.76494
745 5EJ2 NAD 8.76623
746 1YY5 FAD 8.82353
747 1LVL FAD 8.82353
748 1NAA ABL 8.82353
749 1NAA 6FA 8.82353
750 5WP5 SAH 8.82353
751 1LVL NAD 8.82353
752 3TWO NDP 8.82353
753 3QFA FAD 8.8632
754 4URF NAD 8.87097
755 2VDV SAM 8.94309
756 5E8J SAH 9.09091
757 3EVG SAH 9.09091
758 5C8W PCG 9.09091
759 3ICS ADP 9.11765
760 3ICR FAD 9.11765
761 3ICS FAD 9.11765
762 3ICT FAD 9.11765
763 2YVF FAD 9.11765
764 2YVF NAD 9.11765
765 2YVJ NAI 9.11765
766 2YVJ FAD 9.11765
767 1K3T BRZ 9.11765
768 3ICT ADP 9.11765
769 5ZZ6 ADP 9.13461
770 5ZZ6 NAD 9.13461
771 1ZEM NAD 9.16031
772 6BQ6 TER 9.36556
773 1C3V NDP 9.38776
774 3NT6 FAD 9.41177
775 3NTA FAD 9.41177
776 4D04 FAD 9.41177
777 4D04 NAP 9.41177
778 2DC1 NAD 9.41177
779 4TSK NDP 9.41177
780 2DBX GLU 9.47368
781 1V6A TRE 9.63855
782 3NTD FAD 9.70588
783 6ER9 FAD 9.70588
784 1WG8 SAM 9.70588
785 5FUB SAH 9.70588
786 6ER9 NAP 9.70588
787 2FR1 NDP 9.70588
788 3RFV 15L 9.73783
789 5N53 8NB 9.74359
790 3T64 DU3 9.94475
791 3UCL FAD 10
792 3UCL CYH 10
793 3UCL NAP 10
794 5J7X FAD 10
795 5WP4 SAH 10
796 4W6Z 8ID 10
797 1L1E SAH 10.1045
798 1F9A ATP 10.119
799 4XB2 NDP 10.4478
800 4XB2 HSE 10.4478
801 1TE2 PGA 10.6195
802 1RL4 BRR 10.6383
803 6EMU SAM 10.6599
804 5ODQ FAD 10.7143
805 5ODQ 9SB 10.7143
806 5FJN FAD 10.8824
807 5FJN BE2 10.8824
808 5MQ6 NDP 10.8824
809 4R5M NAP 10.8824
810 5YEC ATP 10.9244
811 1UP7 NAD 11.1765
812 2CUL FAD 11.2069
813 3G89 SAM 11.245
814 1KYQ NAD 11.3139
815 1L3I SAH 11.4583
816 2CDU ADP 11.4706
817 2CDU FAD 11.4706
818 1PL6 NAD 11.4706
819 1OBB NAD 11.4706
820 1PL6 572 11.4706
821 3VC1 SAH 11.5385
822 5MBX SP5 11.7647
823 5MBX FAD 11.7647
824 4BJZ P3A 11.7647
825 4BJZ FAD 11.7647
826 4AP3 NAP 11.7647
827 4AP3 FAD 11.7647
828 1U2Z SAH 11.7647
829 2HK9 ATR 12
830 2HK9 NAP 12
831 4B4U NAP 12.0588
832 5NMX FAD 12.0588
833 5NMX NAP 12.0588
834 2DFV NAD 12.0588
835 2GAG NAD 12.1212
836 2GAG FAD 12.1212
837 2GAG FOA 12.1212
838 4J56 FAD 12.6471
839 2ZXI FAD 12.6471
840 4JK3 NAD 12.7413
841 4J4H NAI 12.7413
842 4J4H 1J1 12.7413
843 2GBB CIT 12.8205
844 1GET FAD 12.9412
845 1GET NAP 12.9412
846 3AD8 NAD 13.1313
847 3AD8 PYC 13.1313
848 3AD8 FAD 13.1313
849 6F3M NAD 13.2353
850 6F3N NAD 13.2353
851 6F3N ADN 13.2353
852 1PS9 FAD 13.5294
853 1PS9 NAP 13.5294
854 4AT0 FAD 13.5294
855 2P41 SAH 13.5294
856 2WPF WPF 14.1176
857 2WPF FAD 14.1176
858 3LXD FAD 14.1176
859 3FG2 FAD 14.1176
860 6BJO DUY 14.4
861 1KNR FAD 14.4118
862 4II2 ATP 14.4578
863 3GFB NAD 14.7059
864 3H8V ATP 14.726
865 4UUU SAM 15.4839
866 1BZL GCG 15.5882
867 1BZL FAD 15.5882
868 5YB7 FAD 15.5882
869 5YB7 ORN 15.5882
870 4X9M FAD 16.1765
871 3GRU AMP 16.9492
872 1XCL SAH 17.0213
873 5O96 SAM 17.1429
874 5H81 NAP 17.3529
875 3NJ4 NAD 17.3529
876 3NJ4 AFX 17.3529
877 1LSS NAD 17.8571
878 3CGB FAD 17.9412
879 5U8U FAD 19.4118
880 3Q9T FAY 19.4118
881 1P1C SAH 20.1005
882 6FA4 D1W 20.2312
883 3CGD FAD 20.5882
884 3CGD COA 20.5882
885 3CGD NAD 20.5882
886 3LAD FAD 20.5882
887 4HSU FAD 23.3333
888 1TDF FAD 23.5294
889 1TDF NAP 23.5294
890 3UOY NAP 23.5294
891 3UOY FAD 23.5294
892 5ZI2 NAD 23.5294
893 5ZI2 ADP 23.5294
894 2RAB NAD 24.1176
895 2RAB FAD 24.1176
896 6F5Z SAH 24.5902
897 4YKG FAD 27.0588
898 4YKG NAD 27.0588
899 4GQB 0XU 27.2727
900 1VDC FAD 27.3529
901 1FL2 FAD 27.3529
902 6FP4 E1T 27.9412
903 6FP4 FAD 27.9412
904 4M38 SAH 28.5714
905 5FA5 MTA 30
906 3IWD M2T 30.6452
907 3LZW NAP 34.6386
908 3LZW FAD 34.6386
909 4USR FAD 35
910 5DX0 SFG 35
911 6GAS FAD 35.0453
912 3AB1 FAD 35.2941
913 1MO9 FAD 37.0588
914 1MO9 KPC 37.0588
915 2Q0L FAD 37.6206
916 2Q0L NAP 37.6206
917 3F8D FAD 38.0805
918 4UP3 FAD 40.4459
919 4UP3 NDP 40.4459
920 2Q7V FAD 40.6154
921 5NII FAD 40.7767
922 5VN0 FAD 41.4706
923 5VN0 NAI 41.4706
924 6GNC FAD 42.1769
925 5J60 FAD 42.1875
926 3CTY FAD 42.3197
927 3ITJ FAD 42.3529
928 6GNA FAD 44.0972
929 5K0A FAD 44.2424
930 5MIT FAD 45.2599
931 5MIT NAP 45.2599
Pocket No.: 2; Query (leader) PDB : 4JNA; Ligand: FAD; Similar sites found with APoc: 55
This union binding pocket(no: 2) in the query (biounit: 4jna.bio1) has 50 residues
No: Leader PDB Ligand Sequence Similarity
1 5WJ6 B4A 1.47059
2 2G50 PYR 1.47059
3 5W7M SAH 1.60256
4 3ZF8 GDP 1.96721
5 2JBH 5GP 2.05882
6 6GZD LCI 2.05882
7 3WXO NIZ 2.35294
8 5NM7 GLY 2.63158
9 3A9Y CYS 2.64706
10 1L7N ALF 3.31754
11 3RK0 AMP 3.37553
12 5ZI9 FLC 3.46154
13 3C8F MT2 3.67347
14 4CT7 TRP 3.7037
15 2PK3 A2R 3.73832
16 4K30 NLG 3.75
17 5WS9 OXL 3.82353
18 5Z21 OXM 3.82353
19 3PMA SCR 3.861
20 3KU0 ADE 3.98406
21 6D5X ATP 4.41176
22 2PAR TMP 4.47761
23 4K79 GAL A2G 5
24 2YPI PGA 5.26316
25 3WLV AZA 5.44872
26 2AL2 PEP 5.58824
27 2AL2 2PG 5.58824
28 3C1O NAP 5.60748
29 6AYU MLI 5.88235
30 3A6T 8OG 5.88235
31 1HSR BHO 6.10465
32 1U1I NAD 6.17647
33 1RQL VSO 6.36704
34 2YIV YIV 6.47059
35 3LN9 FLC 6.47482
36 6ECW SAH 6.98413
37 5IDM C2E 7.26257
38 4CME NAP 7.29167
39 4CLO NAP 7.29167
40 1IXI 2HP 7.35294
41 4PO2 ASN ARG LEU LEU LEU THR GLY 7.35294
42 5L9O GOP 7.46269
43 2JGV ADP 7.94118
44 2D3S TNR 8.26446
45 4FK7 P34 8.73362
46 4A3R CIT 9.11765
47 5JGL SAM 9.11765
48 2JDU MFU 9.56522
49 1G27 BB1 11.9048
50 3TLJ SAH 12.0588
51 6FX2 FUC C4W NAG BMA MAN NAG GAL 13.9535
52 1VCO GLN 14.7059
53 1KDO C 18.5022
54 5CGE 51F 21.4706
55 3ITJ CIT 42.3529
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