Receptor
PDB id Resolution Class Description Source Keywords
4I94 1.8 Å EC: 2.7.11.1 STRUCTURE OF BSK8 IN COMPLEX WITH AMP-PNP ARABIDOPSIS THALIANA PROTEIN KINASE PSEUDO KINASE CFG ALANINE GATEKEEPER TRANBRASSINOSTEROID-SIGNALING AMP-PNP MG2+
Ref.: STRUCTURAL CHARACTERIZATION OF THE RLCK FAMILY MEMB A PSEUDOKINASE WITH AN UNPRECEDENTED ARCHITECTURE J.MOL.BIOL. V. 425 4455 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:402;
B:402;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP B:401;
A:401;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4I94 1.8 Å EC: 2.7.11.1 STRUCTURE OF BSK8 IN COMPLEX WITH AMP-PNP ARABIDOPSIS THALIANA PROTEIN KINASE PSEUDO KINASE CFG ALANINE GATEKEEPER TRANBRASSINOSTEROID-SIGNALING AMP-PNP MG2+
Ref.: STRUCTURAL CHARACTERIZATION OF THE RLCK FAMILY MEMB A PSEUDOKINASE WITH AN UNPRECEDENTED ARCHITECTURE J.MOL.BIOL. V. 425 4455 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 4I94 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 4I94 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 4I94 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4I94; Ligand: ANP; Similar sites found: 261
This union binding pocket(no: 1) in the query (biounit: 4i94.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4XH0 ADP 0.000001843 0.60984 1.33333
2 2VPQ ANP 0.00356 0.42601 1.66667
3 4D52 GXL 0.02139 0.40418 1.66667
4 3V4S ATP 0.002194 0.40262 1.66667
5 2QZT PLM 0.01046 0.41198 1.8018
6 1W2D ADP 0.003376 0.43046 2.26415
7 2VN9 GVD 0.0000001917 0.55756 2.33333
8 4YLL 4E3 0.00001197 0.53887 2.33333
9 2WU6 DKI 0.0000003185 0.53454 2.33333
10 1IOW PHY 0.001913 0.45343 2.33333
11 4OUJ LBT 0.008216 0.42522 2.33333
12 5LRT ADP 0.008656 0.41152 2.33333
13 1E4E ADP 0.004292 0.40248 2.33333
14 3PN1 IVH 0.001518 0.40071 2.33333
15 5VC5 96M 0.0000003365 0.49922 2.42215
16 4LH7 1X8 0.0003709 0.49909 2.66667
17 5C1P ADP 0.0007314 0.45667 2.66667
18 5DZT AMP 0.002267 0.45067 2.66667
19 2R7K AMZ 0.003008 0.43734 2.66667
20 3ETH ATP 0.001848 0.43717 2.66667
21 5C1P DAL DAL 0.0007999 0.40265 2.66667
22 3TII ANP 0.003527 0.40074 2.66667
23 4R78 AMP 0.00005821 0.52159 3
24 1GSA ADP 0.00007179 0.50338 3
25 3I0O ADP 0.001139 0.45294 3
26 4ZS4 ATP 0.0002295 0.45199 3
27 2QK4 ATP 0.0006746 0.42526 3
28 2R85 AMP 0.008839 0.41805 3
29 2YW2 ATP 0.001682 0.4108 3
30 2YRX AMP 0.0007734 0.40358 3
31 3HAV ATP 0.00008745 0.43964 3.01003
32 3VPC ADP 0.0005158 0.42656 3.19149
33 3VPD ANP 0.003808 0.4229 3.20285
34 3IS2 FAD 0.007049 0.42002 3.24675
35 3PDT ADP 0.001342 0.4396 3.27273
36 4OAV ACP 0.0000001311 0.61258 3.33333
37 3UDZ ADP 0.0002765 0.47023 3.33333
38 5MW8 ATP 0.0008134 0.45528 3.33333
39 2HGS ADP 0.002083 0.43664 3.33333
40 1EHI ADP 0.003809 0.40281 3.33333
41 3K5I ADP 0.003136 0.40184 3.33333
42 5K2M ADP 0.002595 0.43402 3.663
43 5C4L 4XR 0.001387 0.45601 3.66667
44 4GLW 0XT 0.001553 0.45191 3.66667
45 4DFU QUE 0.005221 0.4312 3.66667
46 4RDL FUC GAL NDG FUC 0.006742 0.42848 3.66667
47 5C4L SIS 0.01599 0.40586 3.66667
48 1TQP ATP 0.0004834 0.41867 3.90071
49 3GNI ATP 0.0000001124 0.57154 4
50 4QDC ASD 0.00717 0.40275 4
51 4LO2 GAL BGC 0.01182 0.412 4.08163
52 1AUX AGS 0.001366 0.42819 4.18006
53 4CC6 L5Y 0.002589 0.44106 4.33333
54 4AZT LY2 0.003175 0.43173 4.39367
55 3GC0 AMP 0.000006905 0.52032 4.55927
56 4WW7 AMP 0.0002402 0.47739 4.5977
57 5I35 ANP 0.0001234 0.48092 4.66667
58 5IQD GNP 0.0006847 0.47731 4.66667
59 5IQD RIO 0.0007272 0.47731 4.66667
60 5TDF ADP 0.003321 0.42373 4.66667
61 2BKK ADP 0.006866 0.40358 4.73373
62 4CYI ATP 0.000002249 0.56676 5
63 4IX4 ADP 0.00007021 0.49933 5
64 3X01 AMP 0.003871 0.43937 5
65 1ZTH ADP 0.000004186 0.56884 5.03876
66 1ZP9 ATP 0.000012 0.53245 5.03876
67 4O1P ANP 0.0000002971 0.6002 5.33333
68 4U98 ACP 0.0002829 0.46497 5.33333
69 3TDV GDP 0.0006018 0.44399 5.33333
70 4IZY 1J2 0.000008014 0.49964 6
71 4GYI ADP 0.00009637 0.49754 6
72 2ZL7 FUC GAL NGA 0.008682 0.42394 6.1017
73 1O9U ADZ 0.0000009612 0.63185 6.33333
74 3F7Z 34O 0.0000008177 0.56468 6.33333
75 5CKW ANP 0.00001102 0.54884 6.33333
76 3ZRM ZRM 0.00002289 0.50289 6.33333
77 4Y9T PA1 0.0173 0.40649 6.33333
78 4UWH JXM 0.00968 0.40062 6.33333
79 4R38 RBF 0.002081 0.41031 6.42857
80 4NM5 ADP 0.000003042 0.50066 6.66667
81 2WEL K88 0.000001326 0.49771 6.66667
82 2JLD AG1 0.0000009663 0.45435 6.66667
83 4ME6 ADP 0.007866 0.42423 7
84 2IF8 ADP 0.0008073 0.47192 7.33333
85 1IA9 ANP 0.0006618 0.4344 7.5
86 2PUL ACP 0.0000903 0.48693 7.66667
87 4GCZ FMN 0.004825 0.41449 8
88 4AZW ATP 0.0003806 0.46621 8.33333
89 4OCV ANP 0.004413 0.40381 8.44327
90 1S9D AFB 0.01385 0.40117 8.53659
91 3PTG 932 0.000005826 0.50875 8.53994
92 5BRP PNG 0.02149 0.4024 8.66667
93 4UX9 ANP 0.00000001081 0.60962 9.33333
94 2PYW ADP 0.00002146 0.486 9.33333
95 3OCP CMP 0.009113 0.40988 9.35252
96 5X8I SQZ 0.0000003339 0.58026 9.66667
97 4AUA 4AU 0.000005763 0.53984 9.66667
98 4CRL C1I 0.000006114 0.4238 10
99 4CS9 AMP 0.004818 0.41638 10.0529
100 3DNT ATP 0.009146 0.40887 10.3333
101 4BTK DTQ 0.0000211 0.51768 10.6667
102 2ZV2 609 0.000000217 0.63003 10.7383
103 4L9I 8PR 0.000008648 0.53203 11
104 2CSN CKI 0.0000003688 0.50465 11.1111
105 3WVR AMP 0.0008706 0.43809 11.3333
106 5MY8 RXZ 0.000003425 0.47983 11.6667
107 3VOT ADP 0.000263 0.44892 11.6667
108 5VZ0 ADP 0.001147 0.43804 13
109 4KBA 1QM 0.0003741 0.40144 13
110 3BP1 GUN 0.00871 0.43181 13.7931
111 3TTI KBI 0.0000005353 0.48814 14.3333
112 3SXF BK5 0.00001089 0.42034 14.6667
113 3H9R TAK 0.000001773 0.59566 15.5963
114 2QCS ANP 0.00000001925 0.67481 15.6667
115 1RE8 BD2 0.0000004532 0.64266 15.6667
116 3IDB ANP 0.00000001071 0.58562 15.6667
117 3GC8 B45 0.00001217 0.48648 16
118 5BYZ 4WE 0.0000165 0.42537 16
119 5N87 N66 0.0000008911 0.43965 16.2939
120 3HMO STU 0.000002204 0.55832 16.9591
121 4FG8 ATP 0.0000003503 0.5564 17.3333
122 3LQV ADE 0.01176 0.41032 17.9487
123 4D2S DYK 0.000003682 0.56337 17.9577
124 4WB7 ATP 0.00000003783 0.47328 18
125 4OTH DRN 0.00000006117 0.57224 18.6667
126 5LXC 7AA 0.00000008175 0.60967 19.3333
127 4IDT T28 0.0000001101 0.61593 19.6667
128 4H3P ANP 0.0000005295 0.58901 19.6667
129 4H3Q ANP 0.0000006046 0.52275 19.6667
130 4QTB 38Z 0.000001191 0.47235 19.6667
131 5T8O 76Z 0.0000021 0.52518 20
132 2B9F ADP 0.000000161 0.59369 20.3333
133 4YZC STU 0.0000005151 0.6271 20.6667
134 2B9H ADP 0.000000191 0.61199 20.6667
135 2B9J ADP 0.0000002512 0.60008 20.6667
136 2B9I ADP 0.0000001839 0.59098 20.6667
137 3HZT J60 0.000008231 0.55487 20.6667
138 5TA6 79D 0.00003145 0.43945 20.6667
139 4Y85 499 0.000003108 0.55171 21
140 4WB6 ATP 0.0000000201 0.54486 21
141 3FHI ANP 0.00000004215 0.65905 21.3333
142 5UKL SIX 0.00000687 0.55873 21.3333
143 3PVW QRX 0.000000949 0.49185 21.3333
144 3VHE 42Q 0.000001123 0.45831 21.3333
145 3VPB ADP 0.0001813 0.42405 21.4286
146 2QLU ADE 0.000001639 0.62386 21.6667
147 5LI1 ANP 0.00000001396 0.59446 21.6667
148 5LI9 ACP 0.00000341 0.52559 21.6667
149 1XJD STU 0.0000002434 0.57295 22.3333
150 3ALN ANP 0.0000004396 0.54904 22.3333
151 3TXO 07U 0.0000002208 0.59185 22.6667
152 1PHK ATP 0.00000002526 0.65139 22.8188
153 3E7O 35F 0.0000114 0.41916 23.6667
154 5GZ9 ANP 0.0000003362 0.60965 24
155 1CM8 ANP 0.00001388 0.52294 24
156 4WNK 453 0.0000004067 0.48151 24.6667
157 4XYM A12 0.002342 0.41182 24.7826
158 2V7O DRN 0.0000001567 0.56131 25
159 4DC2 ADE 0.00000003719 0.53759 26.3333
160 4LOO SB4 0.00003163 0.49571 26.6667
161 1VJY 460 0.0000006353 0.45886 27.3333
162 2A19 ANP 0.0000001497 0.63769 27.4648
163 2F2U M77 0.0000002586 0.6264 27.6667
164 2VZ6 FEF 0.0000001234 0.63184 28.6667
165 4BHN BH9 0.0000002112 0.56453 28.6667
166 1JPA ANP 0.00000007483 0.43958 28.6667
167 3SLS ANP 0.00000004743 0.5726 29.3333
168 5HQ0 LZ9 0.0000002253 0.56137 29.3333
169 5AWM ANP 0.00000005427 0.65867 29.6667
170 4FL3 ANP 0.0000001441 0.55608 30
171 3E8N VRA 0.0000004106 0.41011 30
172 3E8N ATP 0.0000004106 0.41011 30
173 4EWH T77 0.00000009747 0.50885 30.1818
174 5EFQ ADP 0.0000002283 0.58702 30.3333
175 1ZY5 ANP 0.00001259 0.5248 30.3333
176 4Q5H ANP 0.0004735 0.44791 30.7692
177 4I6H 1C8 0.00006607 0.48281 30.8442
178 1U5R ATP 0.0000005217 0.58603 31
179 1BYG STU 0.00000003453 0.62562 31.295
180 4U0I 0LI 0.00001524 0.54827 31.3333
181 5JKG 6LF 0.00002653 0.5465 31.3333
182 2F57 23D 0.000002467 0.56359 31.6667
183 4Y93 746 0.000001801 0.48725 31.6667
184 5UOX 8GY 0.0000003688 0.54536 31.7343
185 1U59 STU 0.00000008683 0.60514 32.0557
186 1V0O INR 0.00000004228 0.60247 32.2917
187 2XVD AS6 0.000006026 0.5634 32.3333
188 3LXK MI1 0.000001751 0.47611 32.3333
189 3SRV S19 0.00000008425 0.62108 32.491
190 4QMN DB8 0.000008445 0.41163 32.5806
191 4K33 ACP 0.0000001422 0.58237 32.6667
192 4F4P 0SB 0.000008292 0.59337 32.967
193 5MJA 7O3 0.000007043 0.54294 33
194 5C03 AGS 0.000004339 0.53393 33
195 4FF8 14S 0.003288 0.40376 33
196 5USZ SKE 0.0000002137 0.50458 33.218
197 5JFS 6K0 0.000003637 0.59113 33.3333
198 4BKJ STI 0.0004051 0.40665 33.6667
199 4AT3 LTI 0.00001707 0.43158 33.7793
200 4BCN T9N 0.0000005218 0.60276 34
201 4CFU 2WC 0.0000003467 0.6022 34
202 4ASE AV9 0.000009794 0.55156 34
203 4BCQ TJF 0.00001699 0.53988 34
204 4BCM T7Z 0.000001161 0.51925 34
205 3KRL KRL 0.000003599 0.50356 34
206 4AG8 AXI 0.000002259 0.42257 34
207 4GJ3 0XP 0.0000004825 0.61889 34.3333
208 3LXN MI1 0.00000005038 0.58601 34.3333
209 3VRY B43 0.000005293 0.47372 34.3333
210 5LMK 6ZK 0.0000168 0.52583 34.3434
211 2H8H H8H 0.00000003019 0.62393 34.6667
212 1Y57 MPZ 0.0000007432 0.51793 34.6667
213 4YMJ 4EJ 0.0000003994 0.64506 35
214 2XMY CDK 0.0000007287 0.65208 35.3333
215 5HES 032 0.0000008025 0.58974 35.3333
216 2OO8 RAJ 0.001379 0.44293 35.3333
217 4E1Z 0MX 0.000003756 0.4962 35.3952
218 3GQI ACP 0.0000002102 0.58842 35.6667
219 2X2M X2M 0.000001022 0.52574 35.6667
220 5UR1 YY9 0.00003817 0.41445 35.6667
221 3PP0 03Q 0.000001633 0.48226 36.3333
222 5FBN 5WF 0.000002846 0.5881 36.5314
223 2PVF ACP 0.00000009891 0.618 36.6667
224 5DBX ANP 0.000007201 0.54984 36.6667
225 3RI1 3RH 0.000001523 0.4852 36.6667
226 3IGO ANP 0.00002104 0.477 36.6667
227 5JGA 6KC 0.0000008445 0.45446 36.6667
228 1OPK P16 0.000004546 0.43563 36.6667
229 4E93 GUI 0.000001817 0.44657 37.3333
230 2WEI VGG 0.000044 0.49354 37.6307
231 2HK5 1BM 0.000003931 0.55582 38.1481
232 4AU8 Z3R 0.000003118 0.57494 38.1757
233 5LPB ADP 0.0000003163 0.62223 38.5135
234 4WOV 3SM 0.00000949 0.54428 38.6667
235 3O0G 3O0 0.0000002547 0.59981 38.6986
236 1UNH IXM 0.0000006197 0.56304 38.6986
237 5LPZ ADP 0.0000005272 0.57199 39
238 3PLS ANP 0.00000226 0.55784 39
239 5HX8 66P 0.0000002389 0.50902 39
240 2Y6O 1N1 0.000008948 0.48724 39
241 3C1X CKK 0.0001083 0.44832 39
242 4XLI 1N1 0.000006635 0.53713 39.5522
243 2OFV 242 0.00001402 0.55673 39.7112
244 3BU5 ATP 0.000000566 0.58772 40.3333
245 4CLI 5P8 0.000005255 0.58769 40.3333
246 5CEO 50D 0.000009555 0.53302 40.3333
247 3EKK GS2 0.000001982 0.42231 40.3333
248 4CSV STI 0.00008378 0.4446 40.7273
249 1K3A ACP 0.000001918 0.54198 40.8027
250 3NW7 LGV 0.000008047 0.58131 41
251 5KO1 6UY 0.000002067 0.55955 41.6961
252 5H2U 1N1 0.00004184 0.49093 41.9476
253 4NST ADP 0.0000002675 0.60223 42
254 5DA3 58V 0.0000004389 0.61546 42.2642
255 5U6C 7YS 0.000009828 0.49003 42.3333
256 4P5Z Q7M 0.000005634 0.40732 42.3333
257 5EKO N17 0.0001408 0.49003 43
258 3KMW ATP 0.0002043 0.47123 43.1734
259 5EOB 5QQ 0.0000421 0.55382 44
260 3SXS PP2 0.000001005 0.5355 45.1493
261 3UIM ANP 0.000000614 0.56951 48.3333
Pocket No.: 2; Query (leader) PDB : 4I94; Ligand: ANP; Similar sites found: 16
This union binding pocket(no: 2) in the query (biounit: 4i94.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3BRN SRO 0.01961 0.40253 1.27389
2 1I7L ATP 0.000853 0.40103 1.94175
3 1NZY BCA 0.01237 0.41212 2.23048
4 1JXZ BCA 0.01671 0.40583 2.23048
5 1S68 AMP 0.002945 0.40435 2.40964
6 4P25 FUC GAL NAG FUC 0.0158 0.40049 3
7 2GQS ADP 0.009824 0.40033 3.79747
8 5HCT 61P 0.01058 0.40058 4.33333
9 2DVZ GLU 0.01213 0.40184 4.66667
10 5ML3 DL3 0.03233 0.40081 4.69799
11 4BS0 6NT 0.009948 0.4103 5
12 4M51 BEZ 0.01264 0.40523 5.33333
13 1HSR BHO 0.01279 0.41367 6.39535
14 3CBG 4FE 0.02274 0.40622 8.18966
15 5COU ATP 0.009453 0.40109 9.66667
16 2CFM AMP 0.0113 0.40331 11.6667
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