Receptor
PDB id Resolution Class Description Source Keywords
4HOR 1.86 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN IFIT5 WITH 5`-TRIPHOS OLIGOCYTIDINE HOMO SAPIENS TPR RNA BINDING ANTIVIRAL RNA RNA BINDING PROTEIN-RNA CO
Ref.: STRUCTURAL BASIS FOR VIRAL 5'-PPP-RNA RECOGNITION B IFIT PROTEINS. NATURE V. 494 60 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG X:101;
 Part of Protein;
 none;
 submit data
24.305 Mg [Mg+2...
CTP C C C C X:1;
 Valid;
 none;
 submit data
1469.61 n/a P(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4HOR 1.86 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN IFIT5 WITH 5`-TRIPHOS OLIGOCYTIDINE HOMO SAPIENS TPR RNA BINDING ANTIVIRAL RNA RNA BINDING PROTEIN-RNA CO
Ref.: STRUCTURAL BASIS FOR VIRAL 5'-PPP-RNA RECOGNITION B IFIT PROTEINS. NATURE V. 494 60 2013
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 225 families.
1 4HOR - CTP C C C C n/a n/a
2 4HOT - ATP A A A n/a n/a
3 4HOS - UTP U U U n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 67 families.
1 4HOR - CTP C C C C n/a n/a
2 4HOT - ATP A A A n/a n/a
3 4HOS - UTP U U U n/a n/a
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 4HOR - CTP C C C C n/a n/a
2 4HOT - ATP A A A n/a n/a
3 4HOS - UTP U U U n/a n/a
4 5UDK ic50 ~ 500 nM ATP A A A n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: CTP C C C C ; Similar ligands found: 13
No: Ligand ECFP6 Tc MDL keys Tc
1 CTP C C C C 1 1
2 UTP U U U 0.676768 0.925373
3 CDP MG 0.495146 0.942029
4 6MZ C U 0.462069 0.835443
5 G 6MZ C U 0.455782 0.846154
6 DCP MG 0.454545 0.875
7 CSQ 0.442623 0.878378
8 CSV 0.442623 0.878378
9 C3P 0.441176 0.942029
10 CDP RB0 0.433333 0.890411
11 G C 0.42963 0.858974
12 G 5MC C U 0.41358 0.82716
13 CDP 0.4 0.915493
Similar Ligands (3D)
Ligand no: 1; Ligand: CTP C C C C ; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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