Receptor
PDB id Resolution Class Description Source Keywords
4HOR 1.86 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN IFIT5 WITH 5`-TRIPHOS OLIGOCYTIDINE HOMO SAPIENS TPR RNA BINDING ANTIVIRAL RNA RNA BINDING PROTEIN-RNA CO
Ref.: STRUCTURAL BASIS FOR VIRAL 5'-PPP-RNA RECOGNITION B IFIT PROTEINS. NATURE V. 494 60 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG X:101;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
CTP C C C C X:1;
Valid;
none;
submit data
1469.61 n/a [P+](...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4HOR 1.86 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF FULL-LENGTH HUMAN IFIT5 WITH 5`-TRIPHOS OLIGOCYTIDINE HOMO SAPIENS TPR RNA BINDING ANTIVIRAL RNA RNA BINDING PROTEIN-RNA CO
Ref.: STRUCTURAL BASIS FOR VIRAL 5'-PPP-RNA RECOGNITION B IFIT PROTEINS. NATURE V. 494 60 2013
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 199 families.
1 4HOR - CTP C C C C n/a n/a
2 4HOT - ATP A A A n/a n/a
3 4HOS - UTP U U U n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 4HOR - CTP C C C C n/a n/a
2 4HOT - ATP A A A n/a n/a
3 4HOS - UTP U U U n/a n/a
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 43 families.
1 4HOR - CTP C C C C n/a n/a
2 4HOT - ATP A A A n/a n/a
3 4HOS - UTP U U U n/a n/a
4 5UDK ic50 ~ 500 nM ATP A A A n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CTP C C C C ; Similar ligands found: 19
No: Ligand ECFP6 Tc MDL keys Tc
1 CTP C C C C 1 1
2 UTP U U U 0.676768 0.925373
3 C C 0.571429 0.956522
4 U U U U 0.527778 0.913043
5 G G G RPC 0.519685 0.881579
6 A U C C 0.492857 0.857143
7 CDP MG 0.490385 0.902778
8 A G C C 0.470588 0.87013
9 U A C C 0.459259 0.868421
10 G C C C 0.457143 0.858974
11 DCP MG 0.45045 0.84
12 U U 0.448276 0.9
13 CSV 0.442623 0.878378
14 CSQ 0.442623 0.878378
15 C3P 0.441176 0.942029
16 G C 0.42963 0.858974
17 CH 0.423077 0.942029
18 G G G C 0.421429 0.848101
19 CDP 0.4 0.915493
Similar Binding Sites (Proteins are less than 50% similar to leader)
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