Receptor
PDB id Resolution Class Description Source Keywords
4HB2 1.8 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF CRM1-RAN-RANBP1 HOMO SAPIENS HEAT REPEAT NUCLEAR EXPORT RAN-RANBP1 PROTEIN TRANSPORT
Ref.: NUCLEAR EXPORT INHIBITION THROUGH COVALENT CONJUGAT HYDROLYSIS OF LEPTOMYCIN B BY CRM1. PROC.NATL.ACAD.SCI.USA V. 110 1303 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL C:1107;
C:1101;
A:303;
C:1102;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
CL C:1106;
A:305;
C:1104;
C:1105;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
35.453 Cl [Cl-]
MG A:302;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
GNP A:301;
Valid;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
EDO A:304;
C:1103;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4HAT 1.78 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF CRM1 INHIBITOR LEPTOMYCIN B IN COMPLEX RAN-RANBP1 HOMO SAPIENS HEAT REPEAT NUCLEAR EXPORT RAN-RANBP1 LMB LEPTOMYCIN B PROTEIN TRANSPORT-ANTIBIOTIC COMPLEX
Ref.: NUCLEAR EXPORT INHIBITION THROUGH COVALENT CONJUGAT HYDROLYSIS OF LEPTOMYCIN B BY CRM1. PROC.NATL.ACAD.SCI.USA V. 110 1303 2013
Members (13)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 4HB0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 4HAU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 4GPT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 4HAZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 5JLJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 4HB4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 4HB2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4HAW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 4HAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 4HAV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4HAX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 4WVF - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 4HAT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
70% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 4HB0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 4HAU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 4GPT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 4HAZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 5JLJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 4HB4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 4HB2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4HAW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 4HAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 4HAV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4HAX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 4WVF - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 4HAT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
14 3M1I - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 4HB0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 4HAU - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 4GPT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 4HAZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 5JLJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 4HB4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 4HB2 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 4HAW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 4HAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 4HAV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4HAX - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 4WVF - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 4HAT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
14 3M1I - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GNP; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 GDP 0.839506 0.973684
3 GP3 0.82716 0.948718
4 GTP 0.809524 0.973684
5 GNH 0.807229 0.986842
6 G1R 0.77907 0.961039
7 GCP 0.77907 0.948718
8 GSP 0.770115 0.925
9 5GP 0.756098 0.960526
10 G 0.756098 0.960526
11 G2R 0.747253 0.936709
12 GMV 0.747126 0.948718
13 GAV 0.714286 0.936709
14 GP2 0.712644 0.936709
15 G2P 0.711111 0.936709
16 Y9Z 0.708333 0.880952
17 GDP MG 0.696629 0.9
18 GDD 0.690722 0.936709
19 GDC 0.690722 0.936709
20 GKE 0.690722 0.936709
21 GDP BEF 0.688889 0.878049
22 G5P 0.686869 0.948718
23 GPG 0.684211 0.936709
24 GTG 0.683673 0.91358
25 GFB 0.683673 0.936709
26 GDR 0.683673 0.936709
27 JB2 0.68 0.936709
28 GKD 0.68 0.936709
29 G3A 0.676768 0.948718
30 6CK 0.676768 0.91358
31 GDX 0.673267 0.948718
32 ALF 5GP 0.67033 0.86747
33 GTP MG 0.666667 0.9
34 BEF GDP 0.666667 0.86747
35 YGP 0.663265 0.879518
36 GCP G 0.659574 0.911392
37 GPD 0.656863 0.902439
38 GDP AF3 0.645833 0.86747
39 GDP ALF 0.645833 0.86747
40 JB3 0.641509 0.925
41 DBG 0.640351 0.974359
42 G3D 0.638298 0.960526
43 G4P 0.625 0.960526
44 GMP 0.621951 0.857143
45 NGD 0.62037 0.936709
46 GGM 0.618182 0.925926
47 0O2 0.616162 0.960526
48 G G 0.61 0.911392
49 2MD 0.603604 0.870588
50 CAG 0.60177 0.904762
51 U2G 0.590909 0.91358
52 FEG 0.590909 0.858824
53 GDP 7MG 0.590476 0.888889
54 MGD 0.587719 0.870588
55 ZGP 0.585586 0.848837
56 CG2 0.580357 0.91358
57 ANP 0.568421 0.922078
58 PGD 0.567797 0.902439
59 MD1 0.567797 0.870588
60 3GP 0.56044 0.922078
61 TPG 0.558333 0.822222
62 GH3 0.55 0.948052
63 FE9 0.546219 0.778947
64 GPX 0.539216 0.922078
65 G4M 0.539062 0.860465
66 DGI 0.536082 0.9
67 BGO 0.535088 0.901235
68 IDP 0.53125 0.947368
69 DGT 0.53 0.9
70 2GP 0.526882 0.935065
71 G1R G1R 0.520325 0.901235
72 I2C FE2 CMO CMO 0.516667 0.811111
73 U A G G 0.512605 0.911392
74 AGO 0.504202 0.91358
75 G A A A 0.504202 0.9
76 P2G 0.5 0.860759
77 G1G 0.5 0.902439
78 MGP 0.49505 0.936709
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 DGP 0.474227 0.8875
83 DG 0.474227 0.8875
84 G G U 0.473684 0.911392
85 IMP 0.463918 0.934211
86 G2Q 0.462963 0.936709
87 GPC 0.459677 0.858824
88 G C 0.459016 0.878049
89 GTA 0.448276 0.91358
90 G7M 0.444444 0.924051
91 MAP 0.439252 0.898734
92 G G G RPC 0.435484 0.853659
93 B4P 0.434343 0.871795
94 AP5 0.434343 0.871795
95 ADP 0.434343 0.896104
96 A2D 0.43299 0.871795
97 U G A 0.431655 0.86747
98 G G G C 0.426357 0.890244
99 SGP 0.425743 0.807229
100 AU1 0.425743 0.922078
101 BA3 0.424242 0.871795
102 35G 0.423077 0.909091
103 PCG 0.423077 0.909091
104 A G C C 0.423077 0.888889
105 C2E 0.423077 0.897436
106 APC G U 0.421875 0.864198
107 ATP 0.421569 0.896104
108 ACQ 0.419048 0.873418
109 5GP 5GP 0.419048 0.860759
110 AQP 0.417476 0.896104
111 5FA 0.417476 0.896104
112 01G 0.417391 0.880952
113 UNP 0.415842 0.810127
114 AN2 0.415842 0.909091
115 6AD 0.415094 0.821429
116 ITT 0.411765 0.846154
117 M33 0.411765 0.860759
118 G C C C 0.410448 0.901235
119 G U34 0.408 0.86747
120 ACP 0.407767 0.873418
121 APR 0.403846 0.871795
122 AR6 0.403846 0.871795
123 DG DG 0.403509 0.845238
124 A4P 0.403226 0.848837
125 UCG 0.402985 0.888889
126 AD9 0.4 0.873418
127 SAP 0.4 0.851852
128 AGS 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4HAT; Ligand: GNP; Similar sites found: 484
This union binding pocket(no: 1) in the query (biounit: 4hat.bio1) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2NCD ADP 0.000005065 0.61203 2.77778
2 2B8W ALF 5GP 0.000005508 0.52731 3.24074
3 1OBV FMN 0.01045 0.40077 3.5503
4 4ZNL BEF ADP 0.0003892 0.48775 3.57143
5 4U60 SIA 0.02527 0.40585 3.57143
6 1O8B ABF 0.02708 0.40522 3.65297
7 1M26 GAL A2G 0.04412 0.40075 3.7594
8 5I34 GDP 0.00005138 0.53054 3.85488
9 1GOJ ADP 0.0000003075 0.69235 4.28571
10 2OBM ADP 0.0009595 0.49266 4.28571
11 2WOJ ADP ALF 0.00004997 0.47922 4.28571
12 3ZQ6 ADP ALF 0.00004453 0.47218 4.28571
13 2FAH GDP 0.0009187 0.45983 4.28571
14 2F5X ASP 0.02645 0.40985 4.28571
15 1JJV ATP 0.00008514 0.54554 4.36893
16 4ZKD GDP 0.00000000007404 0.7107 4.62963
17 3KC1 2T6 0.003888 0.4231 4.62963
18 4V03 ADP 0.000009333 0.55937 5
19 3EZ2 ADP 0.00009816 0.53019 5
20 2Q2Y ADP 0.0002581 0.46335 5
21 2Q2Y MKR 0.0002994 0.45946 5
22 2OFW ADX 0.0009422 0.43916 5
23 2PEZ DAT 0.000899 0.43222 5
24 1NJF AGS 0.000395 0.41745 5
25 1NJF ADP 0.0002265 0.41376 5
26 2PEZ GGZ 0.000899 0.40538 5
27 4IOK ADP 0.003445 0.40341 5
28 4IOK XPO 0.002089 0.40088 5
29 2AWN ADP 0.0000003133 0.71143 5.09259
30 1YQT ADP 0.0000196 0.58153 5.09259
31 5FTB ANP 0.0000901 0.51254 5.09259
32 4XTR ADP 0.00007752 0.49892 5.09259
33 1G41 ADP 0.0003081 0.48715 5.09259
34 2OZE AGS 0.0001633 0.4845 5.09259
35 4XVU ATP 0.00008185 0.48344 5.09259
36 4XTR ATP 0.00008421 0.48292 5.09259
37 5FHD ADP ALF 0.0001612 0.47999 5.09259
38 2PW0 TRC 0.006518 0.44924 5.09259
39 1H5R THM 0.01997 0.40807 5.09259
40 1UYY BGC BGC 0.03216 0.40533 5.34351
41 3FKQ ATP 0.00005178 0.51219 5.36193
42 1VBO MAN 0.006232 0.43898 5.36913
43 4J0Q GDP 0.00000000171 0.77327 5.55556
44 1OYY AGS 0.00269 0.45164 5.55556
45 2HK9 ATR 0.02351 0.4045 5.55556
46 5KSZ GCP 0.000004086 0.57642 5.71429
47 5GJC ATP 0.00006763 0.53138 5.71429
48 4TTQ ATP 0.00007218 0.52997 5.71429
49 4P32 ADP 0.0006368 0.44989 5.71429
50 4MKG AP5 0.002911 0.42028 5.71429
51 4MKF AP5 0.00418 0.41488 5.71429
52 2ZJ5 ADP 0.03344 0.40645 5.71429
53 5J6Y GLC 0.03493 0.40196 5.71429
54 5J6Y BGC 0.03493 0.40196 5.71429
55 3BFV ADP 0.00002354 0.55422 5.90406
56 1G3Q ADP 0.000009286 0.56669 5.90717
57 1WF3 GNP 0.000000001634 0.64149 6.01852
58 1G6O ADP 0.00013 0.50496 6.01852
59 2DPY ADP 0.0006006 0.49631 6.01852
60 4FRZ ADP 0.000002947 0.40681 6.01852
61 1IHU AF3 0.00008839 0.48661 6.28183
62 1IHU ADP 0.0001126 0.47763 6.28183
63 3BER AMP 0.00658 0.43224 6.4257
64 3MD0 GDP 0.00000000152 0.77588 6.42857
65 1G6H ADP 0.0000006816 0.68159 6.42857
66 4WZ6 ATP 0.00002047 0.5806 6.42857
67 4P4T GDP 0.000004327 0.55478 6.42857
68 3DKP ADP 0.0003784 0.49411 6.42857
69 4IDN GNP 0.00006883 0.49126 6.42857
70 2C9O ADP 0.0001299 0.48408 6.42857
71 2GK6 ADP 0.001812 0.47115 6.42857
72 2ZTS ADP 0.0008687 0.45214 6.42857
73 5G41 AP5 0.002135 0.43099 6.42857
74 3BFX A3P 0.005589 0.41606 6.42857
75 2XTZ GSP 0.00000000001666 0.74538 6.48148
76 2CBZ ATP 0.000001819 0.65072 6.48148
77 5IRR GSP 0.00000002797 0.63643 6.48148
78 2GWH A3P 0.01401 0.40135 6.48148
79 4LJ9 ACP 0.001404 0.46573 6.48968
80 2QEN ADP 0.0002908 0.4043 6.57143
81 3B5J 12D 0.000009768 0.59007 6.58436
82 3W5J GDP 0.0000001913 0.69024 6.86275
83 1YRB GDP 0.00000000005964 0.79411 6.94444
84 2ZFI ADP 0.000009022 0.57497 6.94444
85 5LTJ ADP 0.00004752 0.53219 6.94444
86 3EC1 GDP 0.00000001211 0.5181 6.94444
87 1K6M AGS 0.001332 0.43257 6.94444
88 2GMP NAG MAN 0.0197 0.41934 6.94444
89 3BP1 GUN 0.02134 0.41456 6.94444
90 1CR1 TTP 0.0004954 0.40796 6.94444
91 1UKG MMA 0.03578 0.4072 6.94444
92 2RCN GDP 0.0000000000753 0.82803 7.14286
93 4R43 GDP 0.00143 0.46533 7.14286
94 1VHT BA3 0.0009702 0.46345 7.14286
95 3QKT ANP 0.0003334 0.4539 7.14286
96 4A4Z ANP 0.006745 0.43171 7.14286
97 3KJI ADP 0.0000453 0.43034 7.14286
98 4GOX A3P 0.002883 0.41846 7.14286
99 2UVO NAG 0.03464 0.41088 7.14286
100 2UVO NDG 0.04616 0.40108 7.14286
101 1SVI GDP 0.000000003964 0.75462 7.17949
102 5GVR LMR 0.00006138 0.5707 7.26496
103 2FNA ADP 0.0001384 0.47828 7.28291
104 4BQS ADP 0.00004289 0.54124 7.38636
105 1SVK ALF GDP 0.0000000004316 0.67828 7.40741
106 1BH2 GSP 0.0000000001765 0.67554 7.40741
107 2ODE ALF GDP 0.0000000001877 0.67469 7.40741
108 1Y3A GDP 0.00000003933 0.62277 7.40741
109 2PL3 ADP 0.0002764 0.50722 7.40741
110 3TBK ANP 0.001716 0.47239 7.40741
111 3CNL GNP 0.000000002481 0.76502 7.63359
112 5H56 ADP 0.001701 0.41838 7.69231
113 5H56 TYD 0.001701 0.41838 7.69231
114 3NHB ADP 0.000009229 0.59965 7.84314
115 2C78 GNP 0.00000000005409 0.7526 7.85714
116 2C77 GNP 0.00000000004676 0.65049 7.85714
117 4AG5 ADP 0.00001357 0.5898 7.85714
118 3A4M ADP 0.0000141 0.58171 7.85714
119 4LYA ATP 0.00008553 0.51977 7.85714
120 4RZ3 ADP 0.00005503 0.51099 7.85714
121 3VX3 ADP 0.00009443 0.4951 7.85714
122 1FNN ADP 0.0002263 0.47818 7.85714
123 4YS0 ADP 0.001185 0.4503 7.85714
124 2BIF ANP 0.001453 0.42528 7.87037
125 2BIF SIN 0.002663 0.42501 7.87037
126 5KUT GDP 0.00000009823 0.49324 7.93651
127 4WEI GLC GAL 0.01476 0.42765 7.94224
128 4LC1 GDP 0.00000001326 0.71613 8.01187
129 1TAD GDP 0.0000000004817 0.67365 8.02469
130 1TAD ALF 0.0000000004817 0.65932 8.02469
131 1F9V ADP 0.000003152 0.40569 8.06916
132 1FP6 ADP 0.00005222 0.51776 8.3045
133 1AZT GSP 0.00000000007369 0.6899 8.33333
134 1F5N GNP 0.00001127 0.50491 8.33333
135 2VF7 ADP 0.0002739 0.49517 8.33333
136 4PJ3 ANP 0.003969 0.43025 8.33333
137 2QZ4 ADP 0.0002451 0.49187 8.39695
138 5BQ5 ADP BEF 0.0002331 0.49291 8.46561
139 2WJG GDP 0.00000001008 0.72205 8.51064
140 3Q9L ATP 0.00003235 0.52149 8.57143
141 5IRN ADP 0.00005338 0.51732 8.57143
142 5XDR ADP 0.0001363 0.50992 8.57143
143 1L2T ATP 0.0004577 0.44823 8.57143
144 1APZ ASP 0.01134 0.42929 8.57143
145 5X40 ACP 0.0004509 0.4178 8.57143
146 5TQZ GLC 0.007347 0.44228 8.66667
147 3PQC GDP 0.0000001365 0.64661 8.71795
148 4QM7 GTP 0.00003505 0.5456 8.77193
149 3FB4 AP5 0.003173 0.41874 8.7963
150 2D2F ADP 0.0001266 0.54588 8.8
151 3DCJ THH 0.01314 0.40598 8.83721
152 3AIA SAM 0.01098 0.40963 9.00474
153 2WJH GDP 0.000000007286 0.53067 9.03614
154 2WJH FLC 0.0000006673 0.47611 9.03614
155 3WY9 GDP 0.000000001007 0.78501 9.21659
156 3WYA GDP 0.000000002364 0.75345 9.21659
157 4NON GDP 0.000000251 0.56482 9.25926
158 1PUJ GNP 0.000000004018 0.55267 9.25926
159 1V8K ANP 0.0000001991 0.6575 9.28571
160 5N69 ADP 0.00001682 0.54064 9.28571
161 1P9B GDP 0.000147 0.49156 9.28571
162 3B7G ANP 0.0006926 0.47556 9.28571
163 4GBM A3P 0.005955 0.40521 9.28571
164 2HF9 GSP 0.00000003883 0.65442 9.29204
165 1QAN SAH 0.0008033 0.44179 9.42623
166 1NRJ GTP 0.00000000009617 0.64286 9.49367
167 4HI0 GDP 0.0000006004 0.58606 9.54774
168 2DT9 THR 0.02639 0.40581 9.58084
169 4LPS GDP 0.00000009145 0.66433 9.72222
170 1B0U ATP 0.0004874 0.47264 9.72222
171 1ION ADP 0.00002104 0.43124 9.72222
172 1EXF GLY 0.006648 0.4015 9.72222
173 3COB ADP 0.000000853 0.40948 9.7561
174 1Y63 ADP 0.000005582 0.58536 9.78261
175 5J1J ANP 0.000051 0.49207 9.82456
176 1IK4 PGH 0.01379 0.41222 9.86842
177 3WXM GTP 0.0000000001193 0.67596 10
178 3VMF GTP 0.0000000001806 0.66963 10
179 5KSP GDP 0.000001992 0.59922 10
180 3T34 GDP 0.00001781 0.51125 10
181 4Y4V DAL 0.00447 0.4458 10
182 1OS1 ATP 0.001928 0.40869 10
183 1OS1 PYR 0.002018 0.40298 10
184 5E5U MLI 0.004718 0.41061 10.0503
185 2J5V PCA 0.03743 0.41572 10.0817
186 4D81 ADP 0.0003763 0.47787 10.1852
187 1Z6T ADP 0.0004892 0.4678 10.1852
188 1YBH P22 0.02108 0.40689 10.1852
189 4CVN ADP 0.00002283 0.57074 10.219
190 4MDB RLT 0.02615 0.41362 10.2222
191 4R2I ANP 0.0006012 0.49628 10.4762
192 5LB3 ADP 0.0002718 0.5076 10.5618
193 3MWL 8OX 0.03272 0.40493 10.628
194 1JWY GDP 0.000002973 0.57564 10.6481
195 1JWY ADP 0.00001149 0.56219 10.6481
196 2GDJ ANP 0.0001782 0.51041 10.6481
197 4XGU ADP 0.0001085 0.49756 10.6481
198 3ZFD ANP 0.00000002956 0.51546 10.7143
199 1YTM ATP 0.0003354 0.46609 10.7143
200 3RLF ANP 0.0003341 0.45779 10.7143
201 1ZUI SKM 0.00004789 0.43437 10.7143
202 2JLR ANP 0.0001904 0.4023 10.7143
203 2C04 GCP 0.00003856 0.51802 10.7744
204 1G8S MET 0.01473 0.42592 10.8696
205 1B7T ADP 0.00003403 0.53265 10.8974
206 4PX9 ADP 0.0001622 0.51905 10.9589
207 5H68 AGS 0.0002435 0.42993 11.1111
208 1BO4 COA 0.01254 0.41821 11.3095
209 1M7G ADX 0.0004871 0.44133 11.3744
210 1M7G ADP 0.0005139 0.43729 11.3744
211 1M7G AV2 0.000002625 0.42429 11.3744
212 1JI0 ATP 0.00002047 0.57323 11.4286
213 5L3W GDP 0.00001682 0.5472 11.4286
214 3UIE ANP 0.00004815 0.52548 11.4286
215 1XKV ATP 0.00006801 0.51835 11.4286
216 5I0H ADP BEF 0.000000339 0.51584 11.4286
217 5K5Z ANP 0.0001316 0.47053 11.4286
218 3RC3 ANP 0.003761 0.44928 11.4286
219 1X6V ADP 0.0009796 0.41925 11.5741
220 1UJ2 C5P 0.004052 0.40339 11.5741
221 2YIP YIO 0.03463 0.40519 11.5942
222 3DC4 ADP 0.0000006238 0.65268 11.6279
223 5GOE GDP 0.00000002452 0.68207 12.037
224 2XT3 ADP 0.0000006712 0.66676 12.037
225 3DEF GDP 0.000004052 0.56939 12.037
226 1SQ5 ADP 0.0002518 0.49695 12.037
227 2Z5F A3P 0.004093 0.41861 12.037
228 4YMU ATP 0.00001404 0.57333 12.1429
229 1XMV ADP 0.0001281 0.51123 12.1429
230 5M7P ADP 0.002096 0.43507 12.1429
231 3VM7 GLC 0.0105 0.43463 12.1429
232 3R7F CP 0.02514 0.4134 12.1429
233 1I9G SAM 0.008281 0.40212 12.1429
234 1R18 SAH 0.007799 0.40027 12.1429
235 5CK5 GDP 0.00000000009314 0.83783 12.5
236 2IYL GDP 0.000005212 0.58685 12.5
237 1H65 GDP 0.0000125 0.52298 12.5
238 4WZA ADP 0.0000512 0.51198 12.5
239 4WZA ACP 0.00005259 0.51148 12.5
240 3IO3 ADP 0.00007053 0.43132 12.5
241 2IXE ATP 0.0003203 0.46267 12.5461
242 2VOH CIT 0.003095 0.44955 12.7389
243 3U6B GDP 0.0000000005244 0.79949 12.8571
244 2BVN GNP 0.0000000001623 0.77389 12.8571
245 3TK1 GDP 0.000000003442 0.77104 12.8571
246 5JBQ GDP 0.000000001767 0.75974 12.8571
247 4G5G GDP 0.000000001769 0.75972 12.8571
248 3U6K GDP 0.000000003747 0.74348 12.8571
249 4PC3 GDP 0.0000000991 0.64434 12.8571
250 1D8T GDP 0.000000001559 0.52923 12.8571
251 1R6B ADP 0.0003121 0.49241 12.8571
252 3FVQ ATP 0.0002938 0.4686 12.8571
253 4PFO ADP 0.0001177 0.45067 12.8571
254 1FQK ALF 0.00000007126 0.71756 12.9252
255 1FQK GDP 0.0000000227 0.63279 12.9252
256 4TMZ GSP 0.00000000001026 0.77323 12.963
257 5HCN GCP 0.000000001929 0.74587 12.963
258 1T5C ADP 0.000002248 0.64041 12.963
259 1T9D P22 0.01289 0.42636 12.963
260 3TFC PEP 0.03151 0.40581 13.4259
261 4PPF FLC 0.000002006 0.64985 13.5714
262 1ZCB GDP 0.00000004871 0.57978 13.5714
263 3AB3 GDP 0.0000000123 0.57164 13.5714
264 2XTN GTP 0.000002856 0.54463 13.5714
265 2ZR9 DTP 0.00008732 0.52585 13.5714
266 1WY7 SAH 0.005915 0.40534 13.5714
267 1KK8 BEF ADP 0.000008206 0.5486 13.6691
268 3KTA AP5 0.0006901 0.46561 13.7363
269 3CX8 GSP 0.0000000001263 0.68094 13.7931
270 4H1V GNP 0.00000827 0.54845 13.8211
271 1TQ4 GDP 0.00000004252 0.63627 13.8889
272 2OM2 GDP 0.0000002659 0.60151 13.8889
273 2O66 FLC 0.03308 0.40683 14.0741
274 3H4S ADP 0.000001217 0.40404 14.0741
275 1QHG ATP 0.004278 0.42873 14.2857
276 2VVG ADP 0.0000005759 0.40035 14.2857
277 1JJ7 ADP 0.0000006184 0.68321 14.3519
278 5L3V GDP 0.000004605 0.57395 14.3813
279 5L3S GNP 0.00002092 0.50344 14.4295
280 5L3S G 0.04352 0.40065 14.4295
281 2CK3 ANP 0.001227 0.44546 14.7059
282 2CK3 ADP 0.001672 0.42842 14.7059
283 1W0J ADP 0.0001642 0.40731 14.7059
284 4U00 ADP 0.0000009559 0.67173 14.7541
285 5M04 GDP 0.0000000003283 0.80988 14.8148
286 3B9Q MLI 0.00001762 0.59345 15
287 2OG2 MLI 0.00001439 0.58295 15
288 5L3R GCP 0.000003985 0.53311 15
289 4DCT GDP 0.000000001871 0.74651 15.2778
290 5MVR ADP 0.0000432 0.54108 15.4321
291 4P3Y GDP 0.0000000006617 0.5272 15.7143
292 2VB6 ADP BEF 0.00003005 0.50171 16.1074
293 2V7Q ATP 0.00008249 0.51436 16.6667
294 2V7Q ADP 0.0002618 0.50209 16.6667
295 1XP8 AGS 0.0003002 0.50539 17.1429
296 3H86 AP5 0.002211 0.41927 17.1875
297 2W58 ADP 0.000001777 0.65425 17.3267
298 4OI4 ATP 0.001834 0.42673 17.3913
299 5H67 ATP 0.004352 0.43669 17.5
300 5TSH ADP 0.00005181 0.55753 17.8571
301 5TSH ANP 0.0000502 0.53783 17.8571
302 4OHY ANP 0.0001605 0.46698 17.8571
303 3MB5 SAM 0.005182 0.40477 17.8571
304 5J1S ATP 0.001508 0.42689 17.8862
305 3E70 GDP 0.000003081 0.59 17.9878
306 3QF7 ANP 0.001831 0.41855 18
307 3FWY ADP 0.00001437 0.44892 18.1529
308 4WOP CTP 0.0002206 0.47404 18.2222
309 3IIJ ADP 0.00001732 0.56086 18.3333
310 3KIH GDL 0.03885 0.40096 18.5567
311 5MZN ADP 0.001577 0.47432 18.5714
312 5VGR GDP 0.000817 0.45765 18.5714
313 2GCG DGY 0.03201 0.41041 18.5714
314 4KFU ACP 0.000002689 0.4049 18.5714
315 1GXU 2HP 0.000617 0.48875 18.6813
316 4R98 GNH 0.0000004915 0.63795 18.8192
317 4ZG4 VO4 ADP 0.000001129 0.56155 18.9815
318 5KDO GDP 0.000000175 0.60944 19.1176
319 1GOT GDP 0.0000001567 0.60439 19.1176
320 1GP2 GDP 0.000000405 0.58024 19.1176
321 5HR5 ADP 0.0004275 0.47046 19.4444
322 2PS1 ORO 0.02063 0.41132 19.4444
323 2X77 GDP 0.0000000002284 0.79096 19.5767
324 2ZL4 ALA ALA ALA ALA 0.03326 0.40569 19.898
325 1WDT GTP 0.000000001741 0.70611 19.9074
326 1W7J ADP BEF 0.000007013 0.55171 19.9074
327 1CS4 GSP 0.00000000007922 0.70137 20.7547
328 3DOE GTP 0.0000000000145 0.76692 20.8333
329 4E03 ADP 0.00000641 0.43761 20.8738
330 1UPT GTP 0.000000000003559 0.8032 21.0526
331 3AQ4 GDP 0.000000001806 0.74726 21.1957
332 4M9Q GNP 0.00000000001392 0.77784 21.2963
333 1D2N ANP 0.005057 0.41459 21.3235
334 1FQJ ALF 0.00000004655 0.72038 21.4286
335 1FQJ GDP 0.00000001147 0.64524 21.4286
336 2IS6 ADP 0.0001555 0.51336 21.4286
337 4UZI IMD 0.008758 0.41219 21.4286
338 4YDS ATP 0.00002659 0.56727 21.4912
339 1KSH GDP 0.0000000000116 0.66936 21.5054
340 1F6B GDP 0.000000003926 0.73085 21.7172
341 1MR3 G3D 0.000000001208 0.54413 22.0994
342 1LVG ADP 0.000002176 0.41656 22.1429
343 1HTW ADP 0.00001547 0.42209 22.1519
344 1MKY GDP 0.000000001021 0.53365 22.2222
345 1J2J GTP 0.000000000002831 0.79671 22.2892
346 2J59 GTP 0.000000000004104 0.78994 22.2892
347 1O3Y GTP 0.000000000005543 0.78446 22.2892
348 4YLG GDP 0.000000006312 0.69033 22.5434
349 2FH5 GTP 0.000000000004098 0.81166 22.7027
350 4KAX GTP 0.000000000006226 0.69072 23.0769
351 1S9D GDP 0.000000003574 0.73284 23.1707
352 1RE0 GDP 0.0000000003242 0.5326 23.1707
353 2A5F GTP 0.00000000003595 0.6853 23.4286
354 2WIC GNP 0.000000009325 0.71257 23.6111
355 2X7I CIT 0.008105 0.42771 23.7013
356 3ZIA ATP 0.0001823 0.50377 23.8095
357 3ZIA ADP 0.0002985 0.48255 23.8095
358 3PCR GTP 0.00000000007334 0.73736 24.0741
359 3N5C GDP 0.000000001367 0.7653 24.6914
360 2W83 GTP 0.000000000008414 0.77685 24.8485
361 3ZS9 ADP ALF 0.00004006 0.48303 26.3158
362 3A1S GDP 0.000000937 0.61516 26.3889
363 5J6H NCA 0.01542 0.40667 27
364 4HSE ADP 0.00008741 0.51931 27.1429
365 1M2O GNP 0.0000000005144 0.65282 27.3684
366 2GJ8 ALF GDP 0.000000001638 0.6573 27.907
367 4ZI2 GNP 0.000000000004914 0.7972 28.4211
368 4GOJ GNP 0.000000000003809 0.69763 28.5714
369 2QTV GNP 0.0000000001358 0.66472 28.7425
370 2WKQ GTP 0.000000000000431 0.83103 29.1667
371 1FZQ GDP 0.0000000004592 0.78891 29.2818
372 3T12 GDP ALF 0.0000000001908 0.72917 29.2929
373 3T1O GDP 0.00000003405 0.51938 29.2929
374 1YZG GDP 0.000000004607 0.5295 29.6089
375 2J0V GDP 0.00000000118 0.54894 29.717
376 1ZJ6 G3D 0.00000000308 0.73598 30.4813
377 5JCP GDP ALF 0.0000000001172 0.76913 30.5556
378 3REF GDP 0.0000000009166 0.69999 30.9278
379 4BAS GNP 0.0000000003684 0.63006 31.1558
380 1GWN GTP 0.00000000001809 0.66723 31.7073
381 2GCO GNP 0.00000000001452 0.64324 31.8408
382 2GCN GDP 0.000000001573 0.60814 31.8408
383 1RYH GNP 0.000000000006066 0.62642 32.5123
384 1XTQ GDP 0.00000000009892 0.66238 32.7684
385 1DS6 GDP 0.0000000004446 0.54786 33.3333
386 4V0K GDP 0.0000004017 0.57416 33.7278
387 1I4D GDP 0.0000000007149 0.79262 33.8542
388 1QHH ATP 0.007355 0.42557 33.913
389 5DI3 GNP 0.0000000000736 0.74688 34.0541
390 2W2X GSP 0.00000000000627 0.67951 34.0541
391 1OW3 GDP 0.0000000004069 0.59964 34.1969
392 1NF3 GNP 0.0000000000008485 0.79767 34.359
393 1E96 GTP 0.00000000000001843 0.86497 34.375
394 3SBD GNP 0.0000000000001102 0.83351 34.7594
395 1A4R GNH 0.0000000004438 0.74281 35.0785
396 1A4R GDP 0.0000000004521 0.73221 35.0785
397 4D0N GDP 0.000000002048 0.52962 35.1351
398 1CXZ GSP 0.000000000001679 0.71358 35.1648
399 4DID GDP 0.000000001364 0.75319 35.2332
400 1M7B GTP 0.00000000002201 0.77978 35.3261
401 2NGR AF3 0.0000000002344 0.8322 35.6021
402 2NGR GDP 0.00000000004608 0.82478 35.6021
403 1GRN AF3 0.0000000006705 0.80828 35.6021
404 1GRN GDP 0.0000000001007 0.77213 35.6021
405 4ITR GDP 0.00000002473 0.54768 35.6021
406 5HPY GDP 0.0000000004632 0.74196 35.6757
407 3LXR GDP 0.000000005823 0.71176 35.6757
408 2WMO GTP 0.00000000001471 0.83527 35.7895
409 1G4U AF3 0.0000001638 0.70005 35.8696
410 1G4U GDP 0.00000003517 0.64793 35.8696
411 4XOI GTP 0.0000000000003504 0.82379 36.1111
412 2FJU GSP 0.0000000000004872 0.71783 36.5169
413 4XSH GSP 0.00000000002212 0.79061 36.8715
414 1KMQ GNP 0.0000000000006904 0.82244 36.9565
415 3T5G GDP 0.0000000003784 0.572 37.0166
416 1MH1 GNP 0.000000000004776 0.75797 37.0968
417 5IRC GDP 0.000000001467 0.74023 37.0968
418 1TX4 ALF GDP 0.000000000004616 0.78779 37.2881
419 5EE5 GTP 0.000000000001386 0.82073 37.4269
420 4YC7 GNP 0.0000000000009647 0.72041 37.5691
421 3LRE ADP 0.000001442 0.65287 37.8571
422 1HE1 AF3 0.0000000718 0.7019 38.0682
423 1HE1 GDP 0.000000006695 0.67133 38.0682
424 1R4A GNP 0.00000000004338 0.73758 38.7879
425 1ZD9 GDP 0.00000000002897 0.78539 39.3617
426 2G77 GDP 0.0000000002461 0.75446 40.404
427 2G77 AF3 0.0000000936 0.70541 40.404
428 4DKX GDP 0.0000000000175 0.85961 41.6667
429 2F9L GDP 0.0000000007218 0.69567 42.2111
430 2BCG GDP 0.0000000002427 0.74425 42.233
431 4DSU GDP 0.000000000009314 0.74645 42.328
432 2ZEJ GDP 0.000000821 0.55008 42.3913
433 1OIX GDP 0.0000000000001216 0.8318 42.4084
434 4U5X GNP 0.000000000069 0.6334 42.6966
435 1OIV GDP 0.0000000003238 0.6603 42.9319
436 2CJW GDP 0.00000000003805 0.84281 43.75
437 5TB5 GDP 0.00000000006478 0.80466 43.7838
438 5TAR GDP 0.000000000093 0.78514 43.7838
439 5UQW GDP 0.00000000001792 0.75339 43.9153
440 3CPJ GDP 0.00000000001672 0.6266 43.9815
441 2A9K GDP 0.00000000006977 0.62124 44.9198
442 3TKL GTP 0.0000000000001046 0.84542 45.4082
443 1Z06 GNP 0.0000000000005095 0.81709 45.5026
444 3Q85 GNP 0.00000000008606 0.56195 45.5621
445 3BC1 GNP 0.00000000000007305 0.84075 45.641
446 2EW1 GNP 0.0000000000005659 0.741 46.2687
447 4LX0 BEF GDP 0.0000000000000594 0.8119 46.3277
448 1VG8 GNP 0.00000000000001532 0.8346 46.3768
449 1VG0 GDP 0.00000000004117 0.61511 46.3768
450 5XCO GDP 0.00000000002611 0.81079 46.7836
451 5JCZ GDP 0.000000000007052 0.81274 46.9274
452 3Q72 GNP 0.00000000005816 0.5523 46.988
453 1YZN GNP 0.000000000000009548 0.86525 47.027
454 3RWO GDP 0.0000000000609 0.6873 47.027
455 2HV8 GTP 0.000000000001934 0.74442 47.093
456 2A5J GDP 0.00000000002383 0.82532 47.1204
457 1X1R GDP 0.0000000001026 0.70508 47.191
458 4K81 GTP 0.000000000000115 0.81207 47.3684
459 2C5L GTP 0.000000000000005107 0.87589 47.3988
460 4C4P GNP 0.0000000000005819 0.77433 47.3988
461 1ZC3 GNP 0.0000000000002649 0.78737 47.4286
462 5SZH GNP 0.000000000000007105 0.87026 47.7833
463 2D7C GTP 0.0000000000008935 0.75651 47.9042
464 5O2T GSP 0.00000000000001188 0.86143 47.929
465 1UAD GNP 0.00000000000001033 0.8277 48
466 5UFQ GNP 0.00000000005114 0.72569 48.1928
467 3SFV GDP 0.00000000009097 0.6391 48.6188
468 1NVU GTP 0.000000000000008549 0.86713 48.7952
469 2UZI GTP 0.00000000000001354 0.82349 48.7952
470 1CLU DBG 0.00000000005698 0.57419 48.7952
471 5E95 GDP 0.00000000004965 0.7861 48.8095
472 1G16 GDP 0.0000000005774 0.70858 48.8235
473 2HT6 GDP 0.00000000001841 0.56338 48.8506
474 1LFD GNP 0.000000000000009548 0.87655 49.1018
475 1NVV GNP 0.000000000000001443 0.89733 49.3976
476 3KUD GDP 0.0000000000001478 0.87467 49.3976
477 1WQ1 GDP 0.000000000004064 0.79012 49.3976
478 1WQ1 AF3 0.000000008077 0.77191 49.3976
479 1U8Z GDP 0.00000000004165 0.74768 49.4048
480 1Z0J GTP 0.0000000000001312 0.81996 49.4118
481 1KY3 GDP 0.00000000007623 0.60592 49.4506
482 1YVD GNP 0.0000000000002168 0.82163 49.7041
483 5WDR GNP 0.000000000000004552 0.87786 49.7076
484 2Y8E GNP 0.00000000000006306 0.84332 49.7207
485 3DDC GNP 0.000000000000002109 0.89136 50
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