Receptor
PDB id Resolution Class Description Source Keywords
4GYI 2.2 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF THE RIO2 KINASE-ADP/MG2+-PHOSPHOASPARTA FROM CHAETOMIUM THERMOPHILUM CHAETOMIUM THERMOPHILUM PROTEIN KINASE ADP COMPLEX PHOSPHOASPARTATE ACYL-PHOSPHATRIBOSOME BIOGENESIS SER/THR PROTEIN KINASE RIBOSOME BIOGERIBOSOMAL RNA PROCESSING; PRE-40S MATURATION PRE-40S PHOSPHORYLATION TRANSFERASE
Ref.: ATPASE-DEPENDENT ROLE OF THE ATYPICAL KINASE RIO2 O EVOLVING PRE-40S RIBOSOMAL SUBUNIT. NAT.STRUCT.MOL.BIOL. V. 19 1316 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:401;
Valid;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
EDO A:403;
A:404;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
MG A:402;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4GYI 2.2 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF THE RIO2 KINASE-ADP/MG2+-PHOSPHOASPARTA FROM CHAETOMIUM THERMOPHILUM CHAETOMIUM THERMOPHILUM PROTEIN KINASE ADP COMPLEX PHOSPHOASPARTATE ACYL-PHOSPHATRIBOSOME BIOGENESIS SER/THR PROTEIN KINASE RIBOSOME BIOGERIBOSOMAL RNA PROCESSING; PRE-40S MATURATION PRE-40S PHOSPHORYLATION TRANSFERASE
Ref.: ATPASE-DEPENDENT ROLE OF THE ATYPICAL KINASE RIO2 O EVOLVING PRE-40S RIBOSOMAL SUBUNIT. NAT.STRUCT.MOL.BIOL. V. 19 1316 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 4GYI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 4GYI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 4GYI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 435
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 ATP 0.9 1
3 A2D 0.895522 0.971831
4 AQP 0.887324 1
5 5FA 0.887324 1
6 AP5 0.884058 0.971831
7 B4P 0.884058 0.971831
8 BA3 0.869565 0.971831
9 AN2 0.84507 0.985915
10 M33 0.833333 0.958333
11 ACQ 0.826667 0.972222
12 A 0.823529 0.971429
13 AMP 0.823529 0.971429
14 ACP 0.821918 0.972222
15 AR6 0.810811 0.971831
16 APR 0.810811 0.971831
17 ANP 0.802632 0.972222
18 AD9 0.8 0.972222
19 AGS 0.8 0.945946
20 SAP 0.8 0.945946
21 ADX 0.783784 0.873418
22 CA0 0.783784 0.945205
23 TAT 0.779221 0.958904
24 AMP MG 0.774648 0.891892
25 50T 0.773333 0.958333
26 ABM 0.763889 0.917808
27 APC 0.763158 0.958904
28 PRX 0.763158 0.893333
29 ATF 0.759494 0.958904
30 A22 0.753086 0.985915
31 A12 0.743243 0.958904
32 AP2 0.743243 0.958904
33 ADP MG 0.736842 0.905405
34 SRA 0.736111 0.918919
35 ADQ 0.73494 0.945205
36 25L 0.732558 0.985915
37 ADP BEF 0.727273 0.881579
38 BEF ADP 0.727273 0.881579
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 ADP PO3 0.708861 0.943662
44 PAP 0.708861 0.985714
45 ATR 0.708861 0.971429
46 SRP 0.707317 0.906667
47 7D3 0.706667 0.905405
48 25A 0.702381 0.971831
49 ATP MG 0.7 0.905405
50 OAD 0.697674 0.945205
51 RBY 0.6875 0.932432
52 ADV 0.6875 0.932432
53 00A 0.686047 0.883117
54 5SV 0.682353 0.848101
55 8QN 0.682353 0.931507
56 OOB 0.682353 0.931507
57 3OD 0.681818 0.945205
58 BIS 0.681818 0.933333
59 ADP ALF 0.674699 0.87013
60 ALF ADP 0.674699 0.87013
61 AMO 0.674419 0.932432
62 4AD 0.674419 0.92
63 PAJ 0.674419 0.884615
64 GAP 0.670732 0.893333
65 MAP 0.670588 0.945946
66 DLL 0.666667 0.931507
67 ANP MG 0.666667 0.894737
68 VO4 ADP 0.666667 0.931507
69 AHX 0.666667 0.896104
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LAD 0.651685 0.860759
75 WAQ 0.651685 0.883117
76 PR8 0.651685 0.85
77 ITT 0.65 0.943662
78 7D4 0.65 0.905405
79 G5P 0.648936 0.921053
80 RAB 0.647059 0.84507
81 ADN 0.647059 0.84507
82 XYA 0.647059 0.84507
83 TXA 0.644444 0.932432
84 1ZZ 0.644444 0.839506
85 ME8 0.644444 0.839506
86 NB8 0.644444 0.896104
87 FYA 0.644444 0.905405
88 6AD 0.642857 0.909091
89 ADP BMA 0.640449 0.918919
90 G3A 0.638298 0.921053
91 DAL AMP 0.632184 0.905405
92 AFH 0.631579 0.884615
93 9SN 0.630435 0.871795
94 GTA 0.625 0.886076
95 YAP 0.623656 0.894737
96 FA5 0.623656 0.906667
97 UP5 0.622449 0.92
98 XAH 0.617021 0.839506
99 AV2 0.616279 0.917808
100 AOC 0.615385 0.821918
101 48N 0.612245 0.896104
102 4UV 0.610526 0.894737
103 TXD 0.606061 0.907895
104 DND 0.606061 0.932432
105 NAX 0.606061 0.873418
106 NXX 0.606061 0.932432
107 NAI 0.606061 0.907895
108 6V0 0.606061 0.896104
109 5N5 0.605634 0.819444
110 5AS 0.604938 0.77907
111 A4P 0.60396 0.843373
112 DAT 0.60241 0.905405
113 A2R 0.602273 0.985915
114 TXE 0.6 0.907895
115 OMR 0.6 0.851852
116 4UU 0.597938 0.894737
117 A A 0.597826 0.944444
118 A4D 0.597222 0.819444
119 5CD 0.597222 0.805556
120 AP0 0.594059 0.896104
121 4TC 0.594059 0.896104
122 A3P 0.592593 0.971429
123 139 0.592233 0.873418
124 T5A 0.592233 0.841463
125 7D5 0.592105 0.878378
126 ATP A A A 0.589474 0.930556
127 LAQ 0.585859 0.839506
128 MYR AMP 0.585106 0.817073
129 YLP 0.58 0.819277
130 UPA 0.578431 0.907895
131 7DD 0.578313 0.985714
132 ADJ 0.576923 0.851852
133 3AM 0.576923 0.929577
134 COD 0.575472 0.811765
135 NAD 0.575472 0.931507
136 3AT 0.574713 0.971831
137 JB6 0.574468 0.883117
138 4UW 0.574257 0.860759
139 EP4 0.573333 0.753247
140 A2P 0.573171 0.957143
141 CNA 0.571429 0.932432
142 TYM 0.568627 0.906667
143 PPS 0.568182 0.873418
144 TYR AMP 0.56701 0.881579
145 DTA 0.565789 0.786667
146 M2T 0.565789 0.734177
147 AR6 AR6 0.565657 0.917808
148 A3D 0.564815 0.918919
149 3DH 0.564103 0.773333
150 G5A 0.563218 0.77907
151 YLB 0.563107 0.819277
152 YLC 0.563107 0.839506
153 AMP DBH 0.561224 0.893333
154 MTA 0.558442 0.773333
155 DTP 0.556818 0.905405
156 AHZ 0.554455 0.817073
157 NA7 0.553191 0.958904
158 IOT 0.552381 0.831325
159 7MD 0.55 0.8625
160 ZAS 0.55 0.766234
161 IMO 0.548781 0.929577
162 YLA 0.54717 0.819277
163 NAE 0.544643 0.894737
164 TAD 0.544554 0.884615
165 A5A 0.544444 0.807229
166 2AM 0.544304 0.943662
167 TSB 0.543478 0.819277
168 6RE 0.54321 0.759494
169 AYB 0.542056 0.809524
170 NAQ 0.539823 0.871795
171 V3L 0.539326 0.971831
172 ARG AMP 0.539216 0.829268
173 AF3 ADP 3PG 0.538462 0.8375
174 SSA 0.538462 0.8
175 LA8 ALF 3PG 0.538462 0.8375
176 ALF ADP 3PG 0.538462 0.8375
177 ZID 0.535088 0.918919
178 LPA AMP 0.533981 0.817073
179 54H 0.532609 0.788235
180 52H 0.532609 0.77907
181 VMS 0.532609 0.788235
182 BTX 0.53211 0.841463
183 J7C 0.53012 0.769231
184 A3N 0.53012 0.786667
185 5X8 0.528736 0.763158
186 BT5 0.527273 0.831325
187 5CA 0.526882 0.8
188 53H 0.526882 0.77907
189 ARU 0.526316 0.860759
190 EAD 0.525862 0.873418
191 RGT 0.525253 0.958904
192 OVE 0.52439 0.905405
193 S4M 0.52381 0.666667
194 7DT 0.522727 0.985714
195 GDP 0.522222 0.92
196 DDS 0.522222 0.878378
197 AVV 0.521277 0.896104
198 NDE 0.521008 0.932432
199 7MC 0.518868 0.841463
200 DSH 0.518072 0.725
201 MAO 0.517647 0.759036
202 LSS 0.515789 0.761364
203 DSZ 0.515789 0.8
204 NSS 0.515789 0.8
205 P5A 0.515464 0.744444
206 DZD 0.513514 0.884615
207 NVA LMS 0.510417 0.761364
208 12D 0.509615 0.785714
209 NAD IBO 0.509091 0.87013
210 M24 0.508772 0.85
211 YLY 0.508772 0.809524
212 P1H 0.508333 0.851852
213 5AD 0.506849 0.746479
214 GJV 0.505882 0.75
215 LEU LMS 0.505155 0.761364
216 G A A A 0.504505 0.871795
217 4TA 0.504505 0.807229
218 NAJ PZO 0.504425 0.848101
219 KAA 0.5 0.752809
220 NDC 0.5 0.871795
221 7D7 0.5 0.743243
222 71V 0.5 0.907895
223 A3G 0.5 0.8
224 128 0.5 0.776471
225 GSU 0.5 0.77907
226 N0B 0.495726 0.819277
227 NJP 0.495495 0.945946
228 ODP 0.495495 0.909091
229 2SA 0.494624 0.932432
230 6C6 0.494505 0.881579
231 SFG 0.494382 0.75
232 0WD 0.491071 0.921053
233 YSA 0.490196 0.77907
234 PO4 PO4 A A A A PO4 0.489796 0.902778
235 6IA 0.48913 0.8375
236 SAM 0.48913 0.690476
237 A7D 0.488636 0.776316
238 6FA 0.488 0.841463
239 FB0 0.487805 0.804598
240 NAJ PYZ 0.487179 0.85
241 IDP 0.483516 0.918919
242 A5D 0.483516 0.786667
243 SA8 0.483516 0.707317
244 MHZ 0.483146 0.697674
245 PGS 0.483146 0.883117
246 D5M 0.482353 0.878378
247 DA 0.482353 0.878378
248 NEC 0.482353 0.746667
249 NIA 0.481928 0.822785
250 Y3J 0.480519 0.726027
251 FAD 0.480315 0.851852
252 FAS 0.480315 0.851852
253 FDA 0.48 0.833333
254 N6P 0.479592 0.915493
255 GGZ 0.479167 0.825
256 SAH 0.478261 0.74359
257 SAI 0.478261 0.734177
258 NPW 0.477477 0.886076
259 NDP 0.477477 0.921053
260 AAM 0.476744 0.971429
261 AMZ 0.47561 0.916667
262 C2R 0.47561 0.90411
263 A A A 0.474747 0.905405
264 GTP 0.473684 0.92
265 U A G G 0.473684 0.883117
266 SMM 0.473684 0.686047
267 TXP 0.473214 0.921053
268 NZQ 0.473214 0.909091
269 A3S 0.47191 0.810811
270 AMP NAD 0.470588 0.881579
271 SFD 0.46875 0.734043
272 AIR 0.468354 0.901408
273 AAT 0.468085 0.707317
274 EEM 0.468085 0.690476
275 Z5A 0.466667 0.77907
276 7C5 0.466667 0.818182
277 J7V 0.466667 0.833333
278 62F 0.465649 0.8625
279 FAY 0.462121 0.8625
280 ETB 0.461538 0.833333
281 DCA 0.461538 0.823529
282 A3T 0.461538 0.821918
283 A6D 0.46 0.722892
284 A U 0.459459 0.87013
285 6K6 0.459184 0.930556
286 GEK 0.459184 0.7375
287 RFL 0.458647 0.821429
288 S7M 0.458333 0.690476
289 NAP 0.458333 0.945205
290 4YB 0.457944 0.761364
291 WSA 0.454545 0.788235
292 TAP 0.454545 0.907895
293 FNK 0.454545 0.804598
294 COA 0.453782 0.823529
295 0T1 0.453782 0.823529
296 101 0.453488 0.878378
297 XNP 0.452174 0.873418
298 NA0 0.45082 0.932432
299 7RP 0.448276 0.928571
300 GP3 0.446809 0.921053
301 TM1 0.446602 0.77381
302 APU 0.446429 0.894737
303 PUA 0.445378 0.884615
304 V1N 0.443396 0.917808
305 7RA 0.443182 0.957747
306 30N 0.442623 0.752688
307 CAO 0.442623 0.795455
308 AMX 0.442623 0.833333
309 COS 0.442623 0.804598
310 ACK 0.44186 0.861111
311 QQY 0.44186 0.815789
312 649 0.441441 0.744444
313 0UM 0.44 0.698795
314 NHD 0.439655 0.905405
315 CMX 0.439024 0.823529
316 SCO 0.439024 0.823529
317 GCP 0.438776 0.896104
318 8BR 0.438202 0.906667
319 GNH 0.4375 0.907895
320 3AD 0.4375 0.805556
321 62X 0.435644 0.666667
322 ACO 0.435484 0.795455
323 FCX 0.435484 0.795455
324 FAM 0.435484 0.804598
325 GNP 0.434343 0.896104
326 NMX 0.433071 0.76087
327 MGP 0.43299 0.884615
328 PLP AAD 0.432203 0.741573
329 26A 0.432099 0.763158
330 HAX 0.432 0.804598
331 K15 0.431373 0.682353
332 DG1 0.430894 0.921053
333 1DG 0.430894 0.921053
334 QQX 0.430233 0.805195
335 2VA 0.430108 0.8
336 S8M 0.43 0.759494
337 2MC 0.429688 0.769231
338 3KK 0.428571 0.804598
339 6G0 0.428571 0.884615
340 FYN 0.428571 0.823529
341 P5F 0.428571 0.823529
342 NAD BBN 0.428571 0.841463
343 U G A 0.427481 0.839506
344 AS 0.426966 0.833333
345 FAI 0.426966 0.916667
346 RMB 0.426966 0.873239
347 1RB 0.425287 0.885714
348 MCD 0.425197 0.804598
349 OXK 0.425197 0.804598
350 COK 0.425197 0.804598
351 CA6 0.425197 0.729167
352 SOP 0.425197 0.804598
353 G1R 0.424242 0.907895
354 CC5 0.423077 0.816901
355 SXZ 0.423077 0.710843
356 F2N 0.422535 0.813953
357 NAD CJ3 0.422222 0.811765
358 ANZ 0.422018 0.8
359 CMC 0.421875 0.804598
360 CO6 0.421875 0.804598
361 1VU 0.421875 0.795455
362 ZDA 0.421053 0.864865
363 GDD 0.420561 0.884615
364 GKE 0.420561 0.884615
365 GDC 0.420561 0.884615
366 NFD 0.420168 0.883117
367 GSP 0.42 0.873418
368 D3Y 0.42 0.789474
369 MC4 0.419847 0.76087
370 3L1 0.419753 0.773333
371 3D1 0.419753 0.773333
372 FA9 0.41958 0.864198
373 5GP 0.419355 0.906667
374 G 0.419355 0.906667
375 KB1 0.419048 0.698795
376 SCD 0.418605 0.823529
377 CAJ 0.418605 0.804598
378 2BA 0.417582 0.915493
379 CMP 0.417582 0.901408
380 SO8 0.416667 0.789474
381 N01 0.416667 0.905405
382 VRT 0.416667 0.769231
383 3HC 0.415385 0.813953
384 A1S 0.415385 0.804598
385 BCO 0.415385 0.804598
386 IVC 0.415385 0.813953
387 MLC 0.415385 0.804598
388 1HE 0.415385 0.786517
389 NMN AMP PO4 0.415254 0.87013
390 2FA 0.414634 0.813333
391 MGO 0.414141 0.860759
392 3NZ 0.413462 0.782051
393 MCA 0.412214 0.795455
394 CAA 0.412214 0.813953
395 YE1 0.412214 0.813953
396 COO 0.412214 0.804598
397 GAV 0.411765 0.884615
398 P2P 0.411111 0.902778
399 JLN 0.411111 0.890411
400 ZZB 0.410256 0.77381
401 CNV FAD 0.410072 0.793103
402 SCA 0.409091 0.804598
403 RP1 0.409091 0.842105
404 103 0.409091 0.837838
405 2CP 0.409091 0.795455
406 SP1 0.409091 0.842105
407 PAX 0.408 0.829268
408 FAD NBT 0.407143 0.75
409 NVA 2AD 0.40625 0.74359
410 COW 0.406015 0.795455
411 BYC 0.406015 0.804598
412 2KQ 0.406015 0.786517
413 COF 0.406015 0.786517
414 3CP 0.406015 0.804598
415 IRC 0.406015 0.813953
416 1GZ 0.406015 0.795455
417 HGG 0.406015 0.804598
418 CA8 0.406015 0.729167
419 G2P 0.405941 0.884615
420 SLU 0.404959 0.770115
421 U A C C 0.404959 0.858974
422 RBZ 0.404494 0.849315
423 1CZ 0.404412 0.795455
424 BCA 0.402985 0.795455
425 FAQ 0.402985 0.804598
426 4CA 0.402985 0.795455
427 MTP 0.402439 0.730769
428 8OD 0.402062 0.945205
429 CO7 0.401515 0.804598
430 DAL FAD PER 0.401408 0.809524
431 G2R 0.4 0.884615
432 HXC 0.4 0.786517
433 ENQ 0.4 0.916667
434 GMV 0.4 0.896104
435 GRA 0.4 0.804598
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4GYI; Ligand: ADP; Similar sites found: 421
This union binding pocket(no: 1) in the query (biounit: 4gyi.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3HY3 10F 0.01898 0.40115 1.47783
2 4ANW O92 0.000006214 0.58288 1.51134
3 2VPQ ANP 0.0001025 0.50813 1.51134
4 5JFS 6K0 0.0007444 0.48919 1.62338
5 1OBD ATP 0.0001185 0.48779 1.63399
6 1OUK 084 0.002481 0.49844 1.63934
7 2IF8 ADP 0.0000007261 0.54869 1.65289
8 5X8I SQZ 0.000003617 0.56676 1.7341
9 2JDR L20 0.0000203 0.58507 1.75439
10 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.0000203 0.58507 1.75439
11 4WNK 453 0.000003335 0.59241 1.76322
12 4U98 ACP 0.00001746 0.53199 1.76322
13 4G17 0VN 0.00004181 0.51152 1.81818
14 4CLI 5P8 0.0000667 0.546 1.83486
15 3C1X CKK 0.001865 0.44608 1.87668
16 4EN4 GT0 0.005418 0.44449 1.92308
17 4EN4 GT1 0.005418 0.44449 1.92308
18 4EN4 ATP 0.005418 0.44449 1.92308
19 4H3Q ANP 0.000008664 0.55939 1.9337
20 4H3P ANP 0.0002042 0.48492 1.9337
21 4ZS4 ATP 0.0001156 0.49891 1.9544
22 3TDV GDP 0.000007297 0.55251 1.96078
23 4YMJ 4EJ 0.0003235 0.43596 1.97368
24 5MW8 ATP 0.00001063 0.55515 2.01511
25 4XH0 ADP 0.00003329 0.53962 2.01511
26 2JLD AG1 0.00005424 0.53798 2.01511
27 5TT6 ATP 0.005439 0.42395 2.03046
28 5MY8 RXZ 0.000008027 0.56554 2.08877
29 4QTB 38Z 0.00009534 0.51926 2.10526
30 3ORQ ADP 0.000615 0.46694 2.12202
31 3VPD ANP 0.00009287 0.50802 2.13523
32 3AKK ADP 0.0002931 0.47992 2.15385
33 5TDF ADP 0.0001339 0.49825 2.16049
34 4NJH SAM 0.03047 0.40014 2.17391
35 4NJH 2K8 0.03047 0.40014 2.17391
36 3PDT ADP 0.001047 0.44702 2.18182
37 5EOB 5QQ 0.001329 0.48832 2.19436
38 4TWP AXI 0.0002773 0.51558 2.21402
39 5BVE 4VG 0.0001922 0.53755 2.21607
40 4XLI 1N1 0.0002236 0.48057 2.23881
41 2WQN ADP 0.00007239 0.49758 2.25806
42 5CKW ANP 0.0000007018 0.57892 2.267
43 5NCY 8TK 0.000009786 0.56948 2.267
44 3F7Z 34O 0.00004164 0.51717 2.28571
45 1O9U ADZ 0.0000306 0.41135 2.28571
46 4ME6 ADP 0.00002991 0.47645 2.33161
47 2CSN CKI 0.000001831 0.59879 2.3569
48 4XV1 904 0.000171 0.51324 2.39726
49 4JR7 GNP 0.000003998 0.56472 2.40642
50 1Q8Y ADP 0.000003426 0.57349 2.41287
51 2R5T ANP 0.00001225 0.54983 2.41287
52 1Q8Y ADE 0.00002361 0.50284 2.41287
53 5HCY 60D 0.00005531 0.55015 2.41692
54 4O4F IHP 0.00002929 0.54046 2.41935
55 4O4F ATP 0.00002743 0.5398 2.41935
56 2AQX ATP 0.00005965 0.51715 2.42215
57 4FHD 0TT 0.02246 0.40678 2.44565
58 4FHD EEM 0.02246 0.40678 2.44565
59 3LXK MI1 0.00004889 0.53159 2.44648
60 5UIU 8CG 0.00004029 0.53934 2.47678
61 4CQE CQE 0.00008273 0.5104 2.51799
62 4OMJ 2TX 0.007612 0.43139 2.51799
63 2VQD AP2 0.0003304 0.4797 2.51889
64 4IDT T28 0.00001943 0.52983 2.52809
65 1I7L ATP 0.002119 0.44704 2.589
66 3NW7 LGV 0.00104 0.48725 2.60586
67 3LQV ADE 0.003984 0.44253 2.6087
68 5COU ATP 0.009724 0.40441 2.64706
69 5CEO 50D 0.0004512 0.46882 2.66667
70 2R3A SAM 0.00891 0.40821 2.66667
71 1K3A ACP 0.0002726 0.47121 2.67559
72 4G31 0WH 0.001388 0.46813 2.67559
73 3KRL KRL 0.0008919 0.46132 2.68657
74 5DEY 59T 0.0006116 0.50498 2.6936
75 3KRR DQX 0.0000405 0.57506 2.71186
76 4ZGP ADP 0.008749 0.40655 2.73038
77 2Y6O 1N1 0.001034 0.45826 2.74914
78 3ALN ANP 0.0002401 0.48625 2.75229
79 4FL3 ANP 0.0000258 0.53445 2.77078
80 5TO8 7FM 0.0002711 0.51012 2.83688
81 1GSA ADP 0.00003745 0.52902 2.8481
82 2C6Q NDP 0.03957 0.40499 2.849
83 4U0I 0LI 0.0003852 0.49278 2.85714
84 4A4X JUP 0.00008909 0.51705 2.86738
85 5VCV 1N1 0.00003769 0.53106 2.89389
86 5JKG 6LF 0.000854 0.48378 2.89389
87 1EHI ADP 0.001131 0.45235 2.91777
88 5C03 AGS 0.0001492 0.49127 2.92398
89 3EKK GS2 0.0002379 0.51036 2.9316
90 5HES 032 0.0004299 0.47639 2.9316
91 3E8N ATP 0.0001398 0.53079 2.93255
92 3E8N VRA 0.0001398 0.53079 2.93255
93 3L4S NAD 0.02667 0.40417 2.97619
94 5HX8 66P 0.0001466 0.50658 2.98013
95 2PZI AXX 0.00002475 0.51892 3.02267
96 4OAV ACP 0.00007921 0.5015 3.02267
97 2IO8 ADP 0.001487 0.45443 3.02267
98 5DRB 5FJ 0.00009832 0.53977 3.09278
99 2B9H ADP 0.000003569 0.5699 3.11615
100 2B9J ADP 0.000002957 0.56779 3.11615
101 2B9F ADP 0.000003997 0.56473 3.11615
102 1V0O INR 0.0002557 0.48271 3.125
103 3OFM 4B0 0.000174 0.48014 3.14286
104 3VPC ADP 0.00001449 0.54636 3.19149
105 4Y0X ADP 0.000003113 0.56354 3.2
106 3SRV S19 0.000005603 0.5549 3.2491
107 4LOO SB4 0.001857 0.44011 3.27456
108 5ABH YWN 0.01088 0.40958 3.27456
109 5MJA 7O3 0.000818 0.45196 3.27869
110 3SLS ANP 0.0001086 0.50479 3.28947
111 4F4P 0SB 0.00002841 0.57943 3.2967
112 4OH4 ANP 0.000325 0.47548 3.3033
113 2XVD AS6 0.0000522 0.53204 3.31126
114 5LPZ ADP 0.00006265 0.50889 3.31325
115 5EXK 5AD 0.002369 0.40931 3.32326
116 4YLL 4E3 0.00001055 0.55531 3.3241
117 2R7K AMZ 0.0009018 0.47157 3.3241
118 1KJ8 ATP 0.00004115 0.54854 3.32481
119 1KJ8 GAR 0.00004398 0.54854 3.32481
120 4AT3 LTI 0.001146 0.468 3.34448
121 2XMY CDK 0.003062 0.47627 3.3557
122 4NST ADP 0.0001053 0.49835 3.35821
123 3GQI ACP 0.0001525 0.49084 3.37423
124 2GQR ADP 0.001792 0.4386 3.37553
125 5VLQ ANP 0.00003022 0.41372 3.39559
126 2BPM 529 0.0001206 0.53745 3.39623
127 5DA3 58V 0.0008811 0.44143 3.39623
128 1JG3 ADN 0.01477 0.41339 3.40426
129 4CFU 2WC 0.0003353 0.46982 3.43511
130 4BCN T9N 0.0003845 0.46437 3.43511
131 4BCQ TJF 0.0003616 0.45927 3.43511
132 4BCM T7Z 0.001349 0.42205 3.43511
133 5BYZ 4WE 0.0008232 0.47654 3.44828
134 2OO8 RAJ 0.006904 0.41902 3.47003
135 4JNJ BTN 0.006762 0.40959 3.47826
136 1U59 STU 0.00000588 0.55689 3.48432
137 5LMK 6ZK 0.009901 0.40193 3.48837
138 1M0W ANP 0.0001447 0.48666 3.52645
139 4Y93 746 0.0007921 0.46935 3.52645
140 1PK8 ATP 0.001105 0.46238 3.52645
141 5UR1 YY9 0.0009597 0.48586 3.53698
142 4BTK DTQ 0.000009115 0.548 3.56083
143 4Y8D 49J 0.00007065 0.50645 3.57143
144 4P5Z Q7M 0.0002187 0.51353 3.60111
145 3GGF GVD 0.00000855 0.5433 3.65448
146 5LPB ADP 0.0004689 0.45415 3.71622
147 4DFU QUE 0.000001661 0.54397 3.72671
148 5C4L 4XR 0.00002879 0.54826 3.73832
149 5C4L SIS 0.0004939 0.48747 3.73832
150 1FUT 2GP 0.001306 0.41205 3.77358
151 4YZC STU 0.00001991 0.56434 3.77834
152 4E1Z 0MX 0.00003102 0.53293 3.77834
153 4L9I 8PR 0.0002077 0.48206 3.77834
154 2F2U M77 0.0002243 0.48113 3.77834
155 1E4E ADP 0.001941 0.44132 3.79009
156 5JGA 6KC 0.00006642 0.53202 3.80952
157 2QLU ADE 0.005143 0.42335 3.82166
158 3VC1 SAH 0.03453 0.40635 3.84615
159 3VC1 GST 0.03453 0.40635 3.84615
160 1D6H COA 0.04743 0.40168 3.87597
161 5IH9 6BF 0.00001362 0.57103 3.8806
162 4NFN 2KC 0.00008639 0.49975 3.8835
163 4BFM ANP 0.000005951 0.56216 3.89222
164 2DTJ THR 0.009971 0.40365 3.93258
165 3AB4 THR 0.006759 0.40096 3.93258
166 4NZN ANP 0.0000634 0.54712 3.93939
167 4NZN 2OU 0.0000634 0.54712 3.93939
168 2RIO ADP 0.00004888 0.51123 4.03023
169 4PU5 ANP 0.0001233 0.50429 4.03023
170 2HGS ADP 0.001633 0.45068 4.03023
171 5H2U 1N1 0.001176 0.44938 4.03023
172 3Q60 ATP 0.0000382 0.5162 4.04313
173 4WOV 3SM 0.001037 0.44464 4.10095
174 5ENQ 5QE 0.01921 0.40236 4.14201
175 4C2V YJA 0.002527 0.45114 4.21053
176 4R78 AMP 0.00002807 0.5054 4.28212
177 3X01 AMP 0.000008345 0.4928 4.28212
178 1Y57 MPZ 0.0002156 0.49271 4.28212
179 2H8H H8H 0.0001407 0.49247 4.28212
180 4C2W ANP 0.0002145 0.46959 4.30108
181 2Q7D ANP 0.0002678 0.40549 4.33526
182 5EYK 5U5 0.0017 0.45658 4.34783
183 3V4S ADP 0.00005693 0.54001 4.39277
184 3V4S ATP 0.00002938 0.53177 4.39277
185 3LXN MI1 0.00001493 0.54328 4.40252
186 2YAB AMP 0.000001918 0.58258 4.43213
187 4UWH JXM 0.000004284 0.55715 4.49251
188 1AUX AGS 0.0005349 0.46537 4.50161
189 4E93 GUI 0.000006693 0.58128 4.50928
190 1T36 ADP 0.001437 0.46013 4.53401
191 2X1L MET 0.01672 0.40626 4.53401
192 4R33 TRP 0.03151 0.40161 4.53401
193 4R33 SAH 0.03151 0.40161 4.53401
194 5HZX 2GE 0.006566 0.403 4.54545
195 4N70 2HX 0.00001017 0.59279 4.57317
196 2GQS ADP 0.0009514 0.45137 4.64135
197 3M2W L8I 0.000004017 0.55508 4.68227
198 4OCJ NDG 0.00001096 0.57887 4.74934
199 4OCV ANP 0.000002569 0.57662 4.74934
200 1RDS GPC 0.01034 0.40105 4.7619
201 3CY2 MB9 0.00001016 0.5561 4.77707
202 2PYW ADP 0.000000002658 0.72051 4.78589
203 2PUL ACP 0.000002 0.57567 4.78589
204 2QF7 AGS 0.005554 0.43152 4.78589
205 5DZT AMP 0.001586 0.40936 4.78589
206 1UWK URO 0.04626 0.40383 4.78589
207 1UWK NAD 0.04626 0.40383 4.78589
208 4X7Q 3YR 0.000001973 0.57905 4.80769
209 3JRS A8S 0.00779 0.41651 4.80769
210 4F9C 0SX 0.000001776 0.57807 4.86111
211 3KN5 ANP 0.00005428 0.50331 4.92308
212 4GJ3 0XP 0.00003357 0.54498 4.96689
213 3MVH WFE 0.00002392 0.55045 4.97076
214 4IJP 1EH 0.000001583 0.58934 5.02793
215 3PP0 03Q 0.00007173 0.42284 5.02959
216 3FHI ANP 0.000003547 0.58488 5.03778
217 1RE8 BD2 0.00003286 0.56417 5.03778
218 4CYI ATP 0.00006452 0.51323 5.03778
219 1TMM HHR 0.03531 0.40117 5.06329
220 5I35 ANP 0.0000001501 0.62789 5.08906
221 3TXO 07U 0.000002698 0.56641 5.09915
222 4ASE AV9 0.0002409 0.49789 5.09915
223 4EWN 0VR 0.009884 0.40408 5.13834
224 2QCS ANP 0.000004563 0.57958 5.15464
225 5FBN 5WF 0.0008652 0.47966 5.16605
226 5VC5 96M 0.000358 0.48951 5.19031
227 1XJD STU 0.000001036 0.59515 5.21739
228 2YAK OSV 0.00001955 0.55474 5.26316
229 3TII ANP 0.00004665 0.49872 5.26316
230 4OTH DRN 0.00002382 0.5361 5.27859
231 2V58 LZJ 0.0005882 0.49888 5.28967
232 3VRY B43 0.001483 0.4562 5.28967
233 1IA9 ANP 0.00004587 0.51778 5.35714
234 3FHR P4O 0.0001963 0.48811 5.35714
235 2R85 AMP 0.000902 0.47458 5.38922
236 4CRL C1I 0.0002774 0.50282 5.41872
237 4CSV STI 0.001544 0.45185 5.45455
238 5K2M ADP 0.00006878 0.51852 5.49451
239 3H9R TAK 0.0008712 0.43461 5.50459
240 2WU6 DKI 0.000009903 0.55662 5.51181
241 3TKI S25 0.00009966 0.54595 5.57276
242 2HY0 306 0.0006479 0.454 5.59006
243 5EKO N17 0.0008144 0.46513 5.66038
244 4N1T 2GD 0.01798 0.41277 5.66038
245 4IPH 1FJ 0.01979 0.40174 5.69106
246 4AG8 AXI 0.0005801 0.48965 5.6962
247 1PHK ATP 0.00003014 0.52635 5.7047
248 5HVJ ANP 0.0007053 0.41078 5.71429
249 4JDI ANP 0.00005416 0.51682 5.78035
250 5DBX ANP 0.0002006 0.47731 5.79268
251 5VZ0 ADP 0.00003062 0.52066 5.79345
252 3DNT ATP 0.00008685 0.51366 5.79345
253 5FI4 5XV 0.0001582 0.50115 5.79345
254 5DXT 5H5 0.000317 0.47832 5.79345
255 1OPK P16 0.0009531 0.4734 5.79345
256 1GY8 NAD 0.02045 0.40881 5.79345
257 3UIM ANP 0.0007367 0.45887 5.82822
258 1ZY5 ANP 0.0007171 0.45707 5.94059
259 3G5D 1N1 0.00007195 0.55533 5.94406
260 3DLS ADP 0.000001344 0.58036 5.97015
261 4I94 ANP 0.00009637 0.49754 6
262 3T7V SAM 0.003728 0.43177 6
263 5DMZ ADP 0.0000007627 0.59834 6.0274
264 5DH3 5BS 0.0018 0.44488 6.03175
265 2QK4 ATP 0.00002545 0.50116 6.04534
266 4MV1 ADP 0.000354 0.4961 6.04534
267 3TPV ADE 0.0005563 0.46684 6.04534
268 3HZT J60 0.0004048 0.45695 6.04534
269 1OGX EQU 0.001248 0.44349 6.10687
270 5TA6 79D 0.0002315 0.49873 6.14525
271 4K33 ACP 0.0000656 0.51048 6.15385
272 2HKA C3S 0.01498 0.40125 6.15385
273 3DAK ANP 0.0001041 0.49325 6.2069
274 2XK9 XK9 0.00002423 0.55853 6.21118
275 3IDB ANP 0.00001557 0.54723 6.21118
276 4L3L 5FI 0.00001938 0.55493 6.25
277 4AXD ANP 0.00008507 0.53413 6.35965
278 3ZQ6 ADP ALF 0.02386 0.40052 6.48148
279 4NW6 2NS 0.0001001 0.52321 6.50155
280 3AQV TAK 0.001864 0.44003 6.52174
281 2Z7R STU 0.00001002 0.48252 6.54206
282 3VOT ADP 0.00005873 0.49509 6.54912
283 4USF 6UI 0.001411 0.45552 6.57895
284 2PVF ACP 0.00003677 0.51697 6.58683
285 5T8O 76Z 0.000002929 0.57671 6.59026
286 5AWM ANP 0.00000997 0.52869 6.59898
287 4YZN 4K5 0.000004978 0.57089 6.62021
288 2J7T 274 0.003688 0.44307 6.62252
289 4M69 ANP 0.001032 0.4563 6.71378
290 2X4Z X4Z 0.0001478 0.51787 6.75676
291 3ETH ATP 0.00006695 0.51477 6.76056
292 1W2D 4IP 0.00002861 0.5448 6.79245
293 1W2D ADP 0.000004742 0.54173 6.79245
294 3TTI KBI 0.00003991 0.53588 6.80101
295 4O1P ANP 0.00004159 0.5172 6.80101
296 5AX9 4KT 0.0001319 0.49379 6.81818
297 2PVN P63 0.00001689 0.43434 6.81818
298 4HIA FMN 0.02772 0.40548 6.81818
299 3PE2 E1B 0.00002724 0.56835 6.82493
300 2OFV 242 0.0002242 0.51027 6.85921
301 4C5N PXL 0.008391 0.43047 6.88406
302 4C5N ACP 0.007945 0.43047 6.88406
303 1TZD ADP 0.0000006746 0.49851 6.90909
304 4Y85 499 0.001549 0.44154 6.92771
305 5LXT ACP 0.000175 0.49703 6.99301
306 4OUC 5ID 0.0002139 0.47883 7.0028
307 4WHZ 3NL 0.0001895 0.52734 7.01299
308 3RI1 3RH 0.00002886 0.54077 7.02875
309 3SXF BK5 0.00007286 0.53316 7.0529
310 3IGO ANP 0.0001453 0.43678 7.0529
311 5A6N U7E 0.00001439 0.54145 7.06714
312 3C0G 3AM 0.0005426 0.45752 7.12251
313 3VHE 42Q 0.0004573 0.48758 7.24234
314 4FG8 ATP 0.000006191 0.56135 7.30159
315 3UDZ ADP 0.00001845 0.53637 7.30479
316 3V8S 0HD 0.0002715 0.47666 7.30479
317 4IZY 1J2 0.00004872 0.519 7.31707
318 3ZS7 ATP 0.002385 0.44283 7.33333
319 4UX9 ANP 0.000003272 0.57444 7.41758
320 3PTG 932 0.0008379 0.43486 7.43802
321 3E7O 35F 0.0003263 0.49785 7.5
322 5NKB 8ZT 0.0002299 0.51622 7.51634
323 2HK5 1BM 0.0000197 0.53758 7.77778
324 5LXC 7AA 0.000008009 0.54462 7.80856
325 3WO0 ALA 0.0006244 0.49062 7.80856
326 4U44 3D9 0.00008886 0.50179 7.83133
327 5C1P DAL DAL 0.0009731 0.46504 7.84314
328 5C1P ADP 0.0004906 0.45953 7.84314
329 2X2M X2M 0.000163 0.4964 7.96178
330 3TM0 ANP 0.00000448 0.42972 7.98479
331 3TM0 B31 0.000004871 0.42359 7.98479
332 3K5I ADP 0.00007474 0.51021 8.06045
333 5EFQ ADP 0.00009512 0.50041 8.06045
334 3WVR AMP 0.0002538 0.4754 8.06045
335 3K5I AIR 0.001082 0.47211 8.06045
336 5JZJ AN2 0.00000504 0.55704 8.08081
337 3BU5 ATP 0.00006946 0.50679 8.16993
338 5USZ SKE 0.00005977 0.52734 8.3045
339 2BKK ADP 0.00001028 0.53639 8.33333
340 3QCQ 3Q0 0.0003772 0.53636 8.33333
341 5LVP ATP 0.00006362 0.50015 8.36013
342 5W2I ADP 0.000002634 0.58653 8.56031
343 5W2I I3P 0.000002634 0.58653 8.56031
344 3KAL ADP 0.001657 0.4643 8.56423
345 2VZ6 FEF 0.0002384 0.47388 8.6262
346 1RNT 2GP 0.008829 0.41032 8.65385
347 4UAL 3FV 0.00001603 0.53654 8.81612
348 5GZ9 ANP 0.0001434 0.50118 8.85246
349 1BYG STU 0.00005362 0.50654 8.99281
350 4RFM 3P6 0.002668 0.46815 9.02256
351 4WNP 3RJ 0.00002501 0.51871 9.05923
352 3D91 REM 0.04982 0.41087 9.09091
353 5LI9 ACP 0.000007123 0.49903 9.14286
354 1TT8 PHB 0.01804 0.40513 9.14634
355 3ZRM ZRM 0.00004386 0.51612 9.375
356 2PHN GDP 0.006907 0.42235 9.44882
357 2WEL K88 0.0003907 0.43234 9.48012
358 2V7O DRN 0.000009236 0.52208 9.52381
359 2ZV2 609 0.00003314 0.52013 9.73154
360 2YRX AMP 0.0002967 0.44026 9.7561
361 2WEI VGG 0.003029 0.42572 9.7561
362 4AZW ATP 0.0000005218 0.61212 9.82368
363 2YG2 S1P 0.01394 0.40273 9.88372
364 2YG2 FLC 0.02167 0.40123 9.88372
365 3GC8 B45 0.00001428 0.54666 10
366 5W4W 9WG 0.00007607 0.52748 10.2719
367 4KBA 1QM 0.00009452 0.51766 10.2719
368 4IX4 ADP 0.00001047 0.55056 10.2857
369 2VN9 GVD 0.000135 0.47045 10.299
370 3W0O ADP 0.0000007678 0.6237 10.6017
371 3W0O HY0 0.0000007678 0.6237 10.6017
372 4DC2 ADE 0.00002694 0.46529 10.7143
373 3PLS ANP 0.000308 0.47412 10.7383
374 5M06 ADP 0.0002844 0.47312 10.8696
375 4EWH T77 0.00002255 0.54794 10.9091
376 1IOW PHY 0.0004288 0.49484 11.1111
377 1IOW ADP 0.0004288 0.49484 11.1111
378 2YW2 ATP 0.0003125 0.48084 11.335
379 4EUU BX7 0.0002888 0.4923 11.5987
380 4XYM A12 0.0001487 0.49378 11.7391
381 5U6C 7YS 0.0003174 0.48265 12.0635
382 4I6H 1C8 0.001926 0.40961 12.3377
383 5IQD RIO 0.00004283 0.54911 12.459
384 5IQD GNP 0.00004007 0.54911 12.459
385 3SXS PP2 0.0004987 0.47124 12.6866
386 2RIF AMP 0.003731 0.42153 12.766
387 5UOX 8GY 0.00001423 0.54673 12.9151
388 5HQ0 LZ9 0.00006501 0.51307 13.0952
389 4WW7 AMP 0.0000002112 0.63363 13.369
390 4AUA 4AU 0.002484 0.432 13.6808
391 1VJY 460 0.00009913 0.52343 13.8614
392 4BHN BH9 0.00001361 0.54518 14.0719
393 4WB7 ATP 0.00002343 0.55926 14.8148
394 5LI1 ANP 0.000001278 0.59648 15
395 5G1X ADP 0.00005315 0.50954 16.4912
396 5L8L ADP 0.0002711 0.46604 16.4912
397 4BKJ STI 0.003089 0.44082 16.5079
398 4Q5H ANP 0.0000000598 0.58916 16.6667
399 4WB6 ATP 0.000004296 0.58085 17.1429
400 3HMO STU 0.0002239 0.48054 17.2515
401 5EW9 5VC 0.0009426 0.52173 17.3432
402 3E5A VX6 0.0006412 0.40127 17.5373
403 4LRJ ANP 0.000004794 0.55805 17.7515
404 2GU8 796 0.00001599 0.58945 18.1009
405 5LXM ADP 0.000103 0.49619 18.4211
406 2F57 23D 0.0004331 0.4647 18.612
407 3O0G 3O0 0.000179 0.48506 18.8356
408 1UNH IXM 0.0005713 0.4565 18.8356
409 4AU8 Z3R 0.006892 0.40341 18.9189
410 5N87 N66 0.00006148 0.53834 20.7668
411 4D2S DYK 0.0001055 0.4901 20.7746
412 3ORK AGS 0.000007352 0.56738 21.5434
413 4KS7 X4Z 0.00008353 0.51238 21.5753
414 2FAV APR 0.0074 0.42398 23.8889
415 3VPB ADP 0.00001077 0.55938 25
416 2B9I ADP 0.000002903 0.57121 28.5714
417 3PVW QRX 0.00008216 0.51876 31.0811
418 2A19 ANP 0.00002329 0.52732 31.4286
419 5UKL SIX 0.0001798 0.50407 32.2581
420 4NM5 ADP 0.02085 0.42353 33.3333
421 3RE4 TO1 0.000003324 0.54795 38.3721
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