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Receptor
PDB id Resolution Class Description Source Keywords
4EHU 1.6 Å NON-ENZYME: TRANSCRIPT_TRANSLATE ACTIVATOR OF THE 2-HYDROXYISOCAPROYL-COA DEHYDRATASE FROM CL DIFFICILE WITH BOUND ADPNP CLOSTRIDIUM DIFFICILE ACTIN FOLD ATPASE ELECTRON TRANSFER ATP/ADP BINDING 2- HYDROXYISOCAPROYL-COA DEHYDRATASE BINDING ELECTRON TRANSPO
Ref.: ON THE ATP-DEPENDENT ACTIVATION OF THE RADICAL ENZY (R)-2-HYDROXYISOCAPROYL-COA DEHYDRATASE. BIOCHEMISTRY V. 51 6609 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:304;
A:307;
B:303;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
59.044 C2 H3 O2 CC(=O...
ANP A:302;
B:301;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:303;
B:302;
Invalid;
Invalid;
none;
none;
submit data
24.305 Mg [Mg+2...
NA A:305;
A:306;
B:304;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
22.99 Na [Na+]
SF4 A:301;
Part of Protein;
none;
submit data
351.64 Fe4 S4 [S]12...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4EHU 1.6 Å NON-ENZYME: TRANSCRIPT_TRANSLATE ACTIVATOR OF THE 2-HYDROXYISOCAPROYL-COA DEHYDRATASE FROM CL DIFFICILE WITH BOUND ADPNP CLOSTRIDIUM DIFFICILE ACTIN FOLD ATPASE ELECTRON TRANSFER ATP/ADP BINDING 2- HYDROXYISOCAPROYL-COA DEHYDRATASE BINDING ELECTRON TRANSPO
Ref.: ON THE ATP-DEPENDENT ACTIVATION OF THE RADICAL ENZY (R)-2-HYDROXYISOCAPROYL-COA DEHYDRATASE. BIOCHEMISTRY V. 51 6609 2012
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 291 families.
1 4EHU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4EHT - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 247 families.
1 4EHU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4EHT - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 4EHU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4EHT - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4EHU; Ligand: ANP; Similar sites found with APoc: 224
This union binding pocket(no: 1) in the query (biounit: 4ehu.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 5DQY BEZ None
2 1BWO LPC None
3 1V84 GAL NDG None
4 5GZ9 MAN 0.724638
5 4LHD GLY 1.44928
6 3LM9 ADP 1.81159
7 4RW3 SHV 1.81159
8 3LM9 FRU 1.81159
9 4WCX ALA 1.81159
10 4XH4 PPI 1.81159
11 5W6Y TRP 1.81159
12 4XH4 ANP 1.81159
13 1H5R G1P 1.81159
14 5NM7 GLY 1.8797
15 3KIF GDL 1.88679
16 2PX6 DH9 2.17391
17 1FUR MLT 2.17391
18 3ZJX BOG 2.17391
19 2D7I NGA 2.17391
20 1FDJ 13P 2.17391
21 2R09 4IP 2.17391
22 1J2Z SOG 2.22222
23 1FHX 4IP 2.32558
24 6ACS CIT 2.32558
25 1TUU AMP 2.53623
26 1TUU ADP 2.53623
27 4BR5 ANP 2.53623
28 2J5V RGP 2.53623
29 1TUU PIS 2.53623
30 6F97 FAD 2.53623
31 5U7W ADE 2.53623
32 3HKW IX6 2.53623
33 3GVL SLB SIA 2.53623
34 1DKU AP2 2.53623
35 2X1L ADN 2.53623
36 4XT8 TMQ 2.71318
37 4XT8 NAP 2.71318
38 1PFK ADP 2.89855
39 3N9R TD3 2.89855
40 2EB5 OXL 2.99625
41 1SAZ ACP 3.26087
42 2FAH MLA 3.26087
43 5XQL C2E 3.26087
44 1M2Z BOG 3.50195
45 3WUR O4B 3.50877
46 3BF1 ADP 3.61446
47 4A62 ANP 3.62319
48 2ZGY GDP 3.62319
49 4KBA 1QM 3.62319
50 5C9P FUC 3.62319
51 6FBA D48 3.62319
52 3LAD FAD 3.62319
53 4JGP PYR 3.68664
54 2PHU MAN MAN MAN BMA MAN 3.96825
55 2PHT MAN MAN MAN BMA MAN 3.96825
56 2PHW MAN MAN MAN BMA MAN MAN MAN 3.96825
57 4DBH OXL 3.98551
58 1LOX RS7 3.98551
59 5WKC TP9 3.98551
60 1YRO UDP 4.06504
61 5C2N NAG 4.16667
62 1PVC ILE SER GLU VAL 4.20168
63 4A2B AGS 4.34783
64 4A2A ATP 4.34783
65 4CZG ADP 4.34783
66 4CZG QH3 4.34783
67 4PL7 ATP 4.34783
68 3VGL ANP 4.34783
69 6BVM EBV 4.34783
70 6GH9 MIX 4.34783
71 6BVK EAV 4.34783
72 5O22 C3R 4.34783
73 3I7S PYR 4.34783
74 5F7J ADE 4.34783
75 4XFR CIT 4.34783
76 1N8V BDD 4.46429
77 4DE3 DN8 4.56274
78 1VBO MAN 4.69799
79 1VBO MAN MAN MAN 4.69799
80 3B6C SDN 4.70085
81 4CBX ATP 4.72441
82 1S9D GDP 4.87805
83 1C3V PDC 4.89796
84 6FOG OXL 4.91071
85 5W7B MYR 4.96454
86 5G6U YJM 4.98084
87 3KDM TES 5.04587
88 1BW9 PPY 5.07246
89 3GKJ HC3 5.17241
90 5M45 AMP 5.35714
91 5LY3 ADP 5.43478
92 5OBY ANP 5.43478
93 5OBU ANP 5.43478
94 3ITJ CIT 5.43478
95 3ITJ FAD 5.43478
96 5UXM TRP 5.43478
97 4YIW NCD 5.43478
98 4GNC ASO 5.43478
99 2UZH IPE 5.45455
100 4OGQ 7PH 5.625
101 4KAX 4IP 5.91716
102 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 6.15942
103 4TQK NAG 6.15942
104 1KNR FAD 6.15942
105 3AXM 6PG 6.15942
106 1O9W NAG 6.21469
107 6B3V ANP 6.52174
108 6B3V 7DQ 6.52174
109 5E70 RCD 6.52174
110 1GVF PGH 6.52174
111 5LTJ ADP 6.52174
112 5OSW DIU 6.52174
113 3P7G MAN 6.84932
114 5VKI THR NGA GAL NAG 6.875
115 5FPE 3TR 6.88406
116 6EOF ADP 6.88406
117 2BUP ATP 6.88406
118 2BUP ADP 6.88406
119 2QWO ADP 6.88406
120 6ASY ATP 6.88406
121 5EXW 7DT 6.88406
122 3LDQ 3P1 6.88406
123 5FPN KYD 6.88406
124 5FJN BE2 6.88406
125 5FJN FAD 6.88406
126 4USI AKG 7.14286
127 5HV7 RBL 7.24638
128 2V7Y ADP 7.6087
129 3QFU ADP 7.6087
130 4DHY GLC 7.6087
131 1NAA 6FA 7.6087
132 1TL2 NDG 7.62712
133 1JXN MFU 7.85124
134 1HBK MYR 7.86517
135 6E1Q CFA 7.97101
136 3WXL ADP 8.10811
137 5UAO FAD 8.33333
138 2D0O ADP 8.69565
139 2IVN ANP 8.69565
140 3B9Q MLI 8.69565
141 6CGZ HL6 8.69565
142 2R4J 13P 8.69565
143 2R4J FAD 8.69565
144 5NC1 NAG 8.86076
145 4A59 AMP 9.05797
146 3LL5 IP8 9.23695
147 4NZF ARB 9.42029
148 2RBK VN4 9.96169
149 4MO4 ACP 10.1449
150 5LJW ANP 10.5072
151 2GUD MAN 10.6557
152 2YCH ATP 10.8696
153 6G3R ADP 10.8696
154 5AR0 GB8 10.8696
155 2HT6 GDP 10.9195
156 2J8R MSL 11.0465
157 3K7S R52 11.1732
158 3WQT ANP 11.2319
159 1YAG ATP 11.2319
160 4ZLU 4PW 12.3188
161 4ZLU ADP 12.3188
162 3AAQ ARU 12.6812
163 2IYF UDP 12.6812
164 4GNI ATP 13.0435
165 5HTX ADP 13.4058
166 2QXL ATP 14.1304
167 4BGB ADP 14.1304
168 6CWH 6LA 14.2857
169 3KIH GDL 14.433
170 2W41 ADP 14.8551
171 2UYT LRH 15.2174
172 2UYT ADP 15.2174
173 5JIC ADP 15.3846
174 5JIC N7E 15.3846
175 1LES GLC FRU 15.3846
176 3VET ADP 15.5797
177 3VET CP 15.5797
178 3VET TOY 15.5797
179 3TTC ADP 16.3043
180 4YDU ADP 17.7536
181 2E2P ADP 18.1159
182 1FQJ ALF 19.0476
183 3BJE URA 21.3768
184 2CB8 MYA 21.8391
185 4CBU ATP 22.1014
186 4B9Q ATP 23.1884
187 4JNE ATP 23.5507
188 2V51 ATP 24.6377
189 2FF6 ATP 24.6377
190 4B1X ATP 24.6377
191 5ZZB ATP 24.6377
192 2FF3 ATP 24.6377
193 4PL8 ATP 24.6377
194 5ZZA ATP 24.6377
195 2A40 ATP 24.6377
196 2PAV ATP 24.6377
197 4PKG ATP 24.6377
198 4PKI ATP 24.6377
199 5YPU ATP 24.6377
200 2A3Z ATP 24.6377
201 1SQK ADP 24.6377
202 3SJH ATP 24.6377
203 2A42 ATP 24.6377
204 2Q97 ATP 24.6377
205 3MN5 ATP 24.6377
206 1KXP ATP 24.6377
207 3U9Z ADP 24.6377
208 4Z94 ATP 24.6377
209 5YEE ATP 24.6377
210 2PBD ATP 24.6377
211 2D1K ATP 24.6377
212 2FXU ATP 24.6377
213 3SJH LAR 24.6377
214 4H03 ATP 24.6377
215 4H03 LAR 24.6377
216 4B1W ATP 25
217 4B1V ATP 28.125
218 4B1V LAB 28.125
219 3MN7 ATP 30.0725
220 3MN6 ATP 30.0725
221 3MN9 ATP 30.0725
222 3U4L ATP 30.4348
223 3CIP ATP 30.7971
224 4EFH ADP 30.7971
Pocket No.: 2; Query (leader) PDB : 4EHU; Ligand: ANP; Similar sites found with APoc: 41
This union binding pocket(no: 2) in the query (biounit: 4ehu.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 6HT0 GQ8 None
2 5AOA PPI 1.44928
3 4GK9 MAN BMA MAN MAN MAN 2.17391
4 2R0D 4IP 2.17391
5 5KXE 6Y2 2.46914
6 5ZYN FAD 2.53623
7 2B5W NAP 2.89855
8 6EGU 43Y 2.89855
9 3KJS NAP 2.89855
10 2GJ5 VD3 3.08642
11 5LX9 OLB 3.16901
12 2NZ2 CIR 3.26087
13 3BF1 PAU 3.61446
14 2WPF FAD 3.62319
15 4MIG G3F 3.62319
16 6BVL EBY 4.34783
17 3AKI AH8 4.71014
18 3AD8 FAD 5.05051
19 3AD8 PYC 5.05051
20 3SQP 3J8 5.07246
21 1G51 AMP 5.43478
22 2HJR CIT 6.52174
23 4XZ3 ACP 6.52174
24 4LO6 SIA GAL 6.84211
25 5HWK BEZ 7.08333
26 4UP4 GAL NAG 7.6087
27 1HBK COA 7.86517
28 3WSG CIT 7.93651
29 1UA4 BGC 8.33333
30 1UA4 GLC 8.33333
31 4JZ8 CIT 8.69565
32 1SQL GUN 8.90411
33 2CJW GDP 9.89583
34 5TSH ANP 10.5072
35 2GUE NAG 10.6557
36 5TQZ GLC 10.6667
37 1H74 ILE 13.0435
38 3R51 MMA 13.125
39 3TKY N7I 13.7681
40 4ZDJ UTP 13.7681
41 2O66 FLC 14.8148
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