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Receptor
PDB id Resolution Class Description Source Keywords
4E03 2.45 Å NON-ENZYME: OTHER STRUCTURE OF PARF-ADP FORM 2 ESCHERICHIA COLI PARTITION SEGREGATION MULTIDRUG RESISTANCE DEVIANT WALKERSEGREGATION UNKNOWN FUNCTION
Ref.: STRUCTURAL MECHANISM OF ATP-INDUCED POLYMERIZATION PARTITION FACTOR PARF: IMPLICATIONS FOR DNA SEGREGA J.BIOL.CHEM. V. 287 26146 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:501;
B:301;
Valid;
Valid;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
MG A:502;
B:302;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4E03 2.45 Å NON-ENZYME: OTHER STRUCTURE OF PARF-ADP FORM 2 ESCHERICHIA COLI PARTITION SEGREGATION MULTIDRUG RESISTANCE DEVIANT WALKERSEGREGATION UNKNOWN FUNCTION
Ref.: STRUCTURAL MECHANISM OF ATP-INDUCED POLYMERIZATION PARTITION FACTOR PARF: IMPLICATIONS FOR DNA SEGREGA J.BIOL.CHEM. V. 287 26146 2012
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4E03 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4DZZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4E03 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4DZZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4E03 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 4DZZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4E03; Ligand: ADP; Similar sites found with APoc: 628
This union binding pocket(no: 1) in the query (biounit: 4e03.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2W58 ADP None
2 3BC1 GNP None
3 1YVD GNP None
4 2FFQ GSP None
5 1E96 GTP None
6 2A5J GDP None
7 3RAB GNP None
8 1ZJ6 G3D None
9 1Z0A GDP None
10 1MH1 GNP None
11 4MKG AP5 None
12 1Z06 GNP None
13 1RYH GNP None
14 1AKY AP5 None
15 2W2X GSP None
16 3W5J GDP None
17 1YZQ GNP None
18 2V5K OXM None
19 1BO4 COA None
20 2B8T THM None
21 4GBM A3P 0.970874
22 3SBD GNP 1.06952
23 5L3W GDP 1.45631
24 5CK5 GDP 1.45631
25 2ZPT A3P 1.45631
26 4FCW ADP 1.45631
27 2X7I CIT 1.45631
28 3OZV FAD 1.45631
29 5TIV A3P 1.45631
30 1SVI GDP 1.53846
31 2BME GNP 1.6129
32 1Z0K GTP 1.74419
33 1ZUI SKM 1.78571
34 6AU6 GDP 1.94175
35 1KK1 GNP 1.94175
36 4X8O AP5 1.94175
37 4PX9 ADP 1.94175
38 4TTQ ATP 1.94175
39 1FNN ADP 1.94175
40 1P72 ADP 1.94175
41 2F3R G5P 1.94175
42 5NM7 GLY 1.94175
43 1VG8 GNP 1.94175
44 2ZW5 COA 1.94175
45 1ZD9 GDP 2.12766
46 1VG1 GDP 2.16216
47 1YZG GDP 2.23464
48 2A5F GTP 2.28571
49 1I4D GDP 2.42718
50 1SVM ATP 2.42718
51 5LB3 ADP 2.42718
52 1D2N ANP 2.42718
53 4DDY DN6 2.42718
54 4JD3 PLM 2.42718
55 3BFX A3P 2.42718
56 5H4S RAM 2.42718
57 1XCL SAH 2.42718
58 1GWN GTP 2.43902
59 1M7B GTP 2.71739
60 4U5X GNP 2.80899
61 2XTZ GSP 2.91262
62 4P4T GDP 2.91262
63 1ZIN AP5 2.91262
64 1D2E GDP 2.91262
65 1WF3 GNP 2.91262
66 4TL6 ANP 2.91262
67 1DAR GDP 2.91262
68 4NON GDP 2.91262
69 1IN4 ADP 2.91262
70 1RRC ADP 2.91262
71 3QF7 ANP 2.91262
72 2B8W ALF 5GP 2.91262
73 1UJ2 ADP 2.91262
74 1UJ2 C5P 2.91262
75 1CR1 TTP 2.91262
76 2ZPA ADP 2.91262
77 1T5C ADP 2.91262
78 2CHG ANP 2.91262
79 6C90 ADP 2.91262
80 1J99 AND 2.91262
81 2D7D ADP 2.91262
82 2J5V PCA 2.91262
83 2ORV 4TA 2.91262
84 4PZ6 GMP 2.91262
85 1H74 ADP 2.91262
86 1OJ4 ANP 2.91262
87 4PNE SAH 2.91262
88 4IV9 FAD 2.91262
89 5J60 FAD 2.91262
90 2ZPA ACO 2.91262
91 1G16 GDP 2.94118
92 2QG6 NMN 3.01508
93 3REF GDP 3.09278
94 3H86 AP5 3.125
95 4CVN ADP 3.14136
96 5KUT GDP 3.1746
97 2ZEJ GDP 3.26087
98 3B5J 12D 3.39806
99 2ODE ALF GDP 3.39806
100 2RCN GDP 3.39806
101 2ZFI ADP 3.39806
102 2ZR9 DTP 3.39806
103 2XAU ADP 3.39806
104 3BER AMP 3.39806
105 2QEN ADP 3.39806
106 5ZBR ANP 3.39806
107 3DC4 ADP 3.39806
108 1OE0 TTP 3.39806
109 4BFW ZVW 3.39806
110 2GWH A3P 3.39806
111 2ZJ5 ADP 3.39806
112 5LLB 6YZ 3.39806
113 1G3M PCQ 3.39806
114 1G3M A3P 3.39806
115 2XCU C5P 3.39806
116 2IVD FAD 3.39806
117 2GCN GDP 3.48259
118 2GCO GNP 3.48259
119 4QM7 GTP 3.50877
120 5E5U MLI 3.51759
121 1OW3 GDP 3.62694
122 1XX6 ADP 3.66492
123 5OCG GNP 3.7037
124 5UQW GDP 3.7037
125 1KSH GDP 3.76344
126 5TAR GDP 3.78378
127 5TB5 GDP 3.78378
128 1KMQ GNP 3.80435
129 1CXZ GSP 3.84615
130 3T5G GDP 3.8674
131 4U00 ADP 3.8835
132 5GVR LMR 3.8835
133 4AG5 ADP 3.8835
134 5U32 GDP 3.8835
135 1S3G AP5 3.8835
136 4DCT GDP 3.8835
137 3B7G ANP 3.8835
138 2IS6 ADP 3.8835
139 1V8K ANP 3.8835
140 5EXT ADP 3.8835
141 4B47 GDP 3.8835
142 2I4I AMP 3.8835
143 1SQ5 ADP 3.8835
144 5KSZ GCP 3.8835
145 1E2K TMC 3.8835
146 3KLL MAL 3.8835
147 5I0H ADP BEF 3.8835
148 2DPY ADP 3.8835
149 4QRH 0O2 3.8835
150 5XQL C2E 3.8835
151 2GQT FAD 3.8835
152 6BSX E7S 3.93258
153 6BSX GDP 3.93258
154 1TX4 ALF GDP 3.9548
155 1F6B GDP 4.0404
156 6FA4 GNP 4.04624
157 1W4R TTP 4.10256
158 1Z08 GNP 4.11765
159 3Q85 GNP 4.14201
160 2NGR GDP 4.18848
161 1GRN GDP 4.18848
162 1A4R GNH 4.18848
163 1A4R GDP 4.18848
164 5KSP GDP 4.21053
165 1M2O GNP 4.21053
166 3KUD GDP 4.21687
167 1WQ1 GDP 4.21687
168 1CLU DBG 4.21687
169 5WLB GNP 4.21687
170 2UZI GTP 4.21687
171 3DDC GNP 4.21687
172 1WQ1 AF3 4.21687
173 1U3G THF 4.2328
174 2WJG GDP 4.25532
175 5Z2M GTP 4.34783
176 2QQ0 TMP 4.34783
177 2QQ0 ADP 4.34783
178 2QQ0 ANP 4.34783
179 2QQ0 THM 4.34783
180 4UXH T5A 4.34783
181 2XT3 ADP 4.36893
182 1TQ4 GDP 4.36893
183 2IYL GDP 4.36893
184 1MKY GDP 4.36893
185 2WKQ GTP 4.36893
186 2XTN GTP 4.36893
187 3IUY AMP 4.36893
188 2VVG ADP 4.36893
189 1R6B ADP 4.36893
190 5I34 GDP 4.36893
191 5WRJ A3P 4.36893
192 5WRI A3P 4.36893
193 2FSH ANP 4.36893
194 1AQU A3P 4.36893
195 4MO4 ACP 4.36893
196 1HE1 GDP 4.44444
197 1HE1 AF3 4.44444
198 5XKT GNP 4.5
199 1TU3 GNP 4.67836
200 1R2Q GNP 4.70588
201 1OIV GDP 4.71204
202 3MJH GTP 4.7619
203 2QTV GNP 4.79042
204 2WJH GDP 4.81928
205 2WJH FLC 4.81928
206 2Y65 ADP 4.85437
207 4H1V GNP 4.85437
208 1TAD GDP 4.85437
209 1TAD ALF 4.85437
210 1GOT GDP 4.85437
211 4KBF AMP 4.85437
212 4Q1A 2XZ 4.85437
213 4Q1A UDP 4.85437
214 1QF9 ALF 4.85437
215 1QF9 ADP 4.85437
216 1QF9 C5P 4.85437
217 1IWE IMP 4.85437
218 1JI0 ATP 4.85437
219 2QZ4 ADP 4.85437
220 3ZFD ANP 4.85437
221 3QXC ATP 4.85437
222 2YOH WMJ 4.85437
223 1Z6T ADP 4.85437
224 1X8J A3P 4.85437
225 2XG5 EC5 4.85437
226 2XG5 EC2 4.85437
227 4K81 GTP 4.85437
228 4R43 GDP 4.85437
229 1I9G SAM 4.85437
230 3ITJ CIT 4.85437
231 4KVL PLM 4.85437
232 2VHJ ADP 4.85437
233 4UTG ANP 4.91329
234 4C4P GNP 5.20231
235 1EK0 GNP 5.29412
236 3COB ADP 5.33981
237 3AB3 GDP 5.33981
238 1VG0 GDP 5.33981
239 1VG9 GDP 5.33981
240 1G4U GDP 5.33981
241 4YMU ATP 5.33981
242 6G14 G4P 5.33981
243 1G7S GDP 5.33981
244 4FRZ ADP 5.33981
245 4WZ6 ATP 5.33981
246 2Q2Y MKR 5.33981
247 3DZD ADP 5.33981
248 2Q2Y ADP 5.33981
249 2O0J ADP 5.33981
250 5K0A FAD 5.33981
251 5IRC GDP 5.47264
252 1FZQ GDP 5.52486
253 1D5C GDP 5.55556
254 4KOT CE3 5.55556
255 1Z0F GDP 5.58659
256 1Z83 AP5 5.61225
257 2WIC GNP 5.61798
258 1S8F GDP 5.64972
259 1NRJ GTP 5.6962
260 1BH2 GSP 5.82524
261 1Y3A GDP 5.82524
262 2OM2 GDP 5.82524
263 5KDO GDP 5.82524
264 3FB4 AP5 5.82524
265 4PFO ADP 5.82524
266 5HPY GDP 5.82524
267 2AWN ADP 5.82524
268 3NHB ADP 5.82524
269 5ZXD ATP 5.82524
270 4HSE ADP 5.82524
271 3TMK T5A 5.82524
272 1BG2 ADP 5.82524
273 3RLF ANP 5.82524
274 4QOS ADP 5.82524
275 3QVV 3QV 5.82524
276 3QVV A3P 5.82524
277 1SVK ALF GDP 5.82524
278 4ITM ATP 5.82524
279 2HF9 GSP 5.82524
280 5EP2 AZU 5.82524
281 1MVN PCO 5.82524
282 2JAQ DCP 5.85366
283 1N62 MCN 6.0241
284 2F9L GDP 6.03015
285 2VB6 ADP BEF 6.04027
286 1S7N COA 6.04396
287 1FQK GDP 6.12245
288 1FQJ GDP 6.12245
289 1FQK ALF 6.12245
290 1YRB GDP 6.31068
291 4NU0 AP5 6.31068
292 2OFW ADX 6.31068
293 2G77 GDP 6.31068
294 3FYH ADP 6.31068
295 1X6V ADP 6.31068
296 2C9O ADP 6.31068
297 2GDJ ANP 6.31068
298 2NCD ADP 6.31068
299 2GK6 ADP 6.31068
300 2JJK R15 6.31068
301 4YS0 ADP 6.31068
302 2PHN GDP 6.31068
303 3KC1 2T6 6.31068
304 4O33 TZN 6.31068
305 4O33 3PG 6.31068
306 1PVC ILE SER GLU VAL 6.31068
307 3CW9 01A 6.31068
308 1B7T ADP 6.41026
309 3QBT GNP 6.42857
310 1V0C ACO 6.43564
311 1V0C KNC 6.43564
312 3LN9 FLC 6.47482
313 4DID GDP 6.57895
314 4WOP CTP 6.66667
315 3P4X ADP 6.79612
316 4RD0 GDP 6.79612
317 1G6H ADP 6.79612
318 3FVQ ATP 6.79612
319 1QF5 RPL 6.79612
320 1QF5 GDP 6.79612
321 4NE2 ADP 6.79612
322 4NE2 SH2 6.79612
323 4R98 GNH 6.79612
324 2Z5F A3P 6.79612
325 3BOS CDP 6.79612
326 5L3R GCP 6.79612
327 4TMK T5A 6.79612
328 3B9Q MLI 6.79612
329 2OG2 MLI 6.79612
330 2D2F ADP 6.79612
331 1V97 MTE 6.79612
332 4ZLU 4PW 6.79612
333 4ZLU ADP 6.79612
334 2A2C ADP 6.79612
335 2A2C NG1 6.79612
336 5GM1 SAH 6.79612
337 4NTD FAD 6.79612
338 1OIX GDP 6.80628
339 1ZC3 GNP 6.85714
340 5BQ5 ADP BEF 6.87831
341 1LFD GNP 6.89655
342 2CDN ADP 6.96517
343 3UIE ANP 7
344 4LJ9 ACP 7.07965
345 4HDO GNP 7.18563
346 1GUA GNP 7.18563
347 2PEZ DAT 7.26257
348 2PEZ GGZ 7.26257
349 5L3S GNP 7.28155
350 1DAK ADP 7.28155
351 1DAK DPU 7.28155
352 5L3V GDP 7.28155
353 6BVI GNP 7.28155
354 6BVK GNP 7.28155
355 6BVJ GNP 7.28155
356 6D56 GNP 7.28155
357 6D59 GNP 7.28155
358 6D5H GNP 7.28155
359 6BVL GNP 7.28155
360 6D5J GNP 7.28155
361 6D5L GNP 7.28155
362 6D55 GNP 7.28155
363 6D5E GNP 7.28155
364 6D5V GNP 7.28155
365 6D5G GNP 7.28155
366 5HCN GCP 7.28155
367 5UIV ADP 7.28155
368 1W5T ANP 7.28155
369 6B4K ANP 7.28155
370 2GKS ADP 7.28155
371 2CE7 ADP 7.28155
372 1G41 ADP 7.28155
373 1YQT ADP 7.28155
374 1W5T ADP 7.28155
375 5YV5 ADP 7.28155
376 1Q20 A3P 7.28155
377 1Q20 PLO 7.28155
378 1NVV GNP 7.28155
379 6BVM GNP 7.28155
380 6D5M GNP 7.28155
381 1OC2 TDX 7.28155
382 1ZQ9 SAM 7.28155
383 3CV2 OXL 7.28155
384 3CX8 GSP 7.38916
385 3H4S ADP 7.40741
386 1OFH ADP 7.47126
387 2HV8 GTP 7.55814
388 5ZB0 TYD 7.57576
389 5ZB0 ADP 7.57576
390 6B8B ADP 7.63052
391 4ZNL BEF ADP 7.66423
392 3KTA AP5 7.69231
393 1XEX ATP 7.69231
394 3KJI ADP 7.76699
395 6CS8 F9Y 7.76699
396 4MKF AP5 7.76699
397 2FJU GSP 7.76699
398 1JJV ATP 7.76699
399 1L2T ATP 7.76699
400 3A1S GDP 7.76699
401 4D81 ADP 7.76699
402 1F5N GNP 7.76699
403 1VHT BA3 7.76699
404 1P9B GDP 7.76699
405 5MEX SZZ 7.76699
406 5MEX PAP 7.76699
407 2V2V V12 7.76699
408 2D7C GTP 7.78443
409 1NF3 GNP 7.8125
410 1KK8 BEF ADP 7.91367
411 5XC5 GTP 7.95455
412 5O2T GSP 8.02139
413 1MJH ATP 8.02469
414 2GJ8 ALF GDP 8.13953
415 3E70 GDP 8.25243
416 4KFU ACP 8.25243
417 3TK1 GDP 8.25243
418 1G6O ADP 8.25243
419 5Z69 AGS 8.25243
420 5AK0 8V1 8.25243
421 4PJ3 ANP 8.25243
422 4IOK ADP 8.25243
423 4IOK XPO 8.25243
424 3MGB PAP 8.25243
425 2ZE7 AMP 8.25243
426 2ZE7 DST 8.25243
427 4R2I ANP 8.25243
428 5YVT NAI 8.25243
429 3Q72 GNP 8.43373
430 5TSH ANP 8.73786
431 5TSH ADP 8.73786
432 3A4M ADP 8.73786
433 1PUJ GNP 8.73786
434 1XKV ATP 8.73786
435 5Y6N ADP 8.73786
436 2GMV UN8 8.73786
437 2FAH GDP 8.73786
438 4NCN GTP 8.73786
439 1NHX FTB 8.73786
440 1NHX PEP 8.73786
441 6DEF GCP 8.73786
442 4A4Z ANP 8.73786
443 2GMV PEP 8.73786
444 1GXU 2HP 8.79121
445 1Z2A GDP 8.92857
446 4ZOH MCN 8.92857
447 1KO8 6PG 9.14286
448 4JLS 3ZE 9.21053
449 3FWY ADP 9.2233
450 3BFV ADP 9.2233
451 1M7G AV2 9.2233
452 3DKP ADP 9.2233
453 1M7G ADX 9.2233
454 1JJ7 ADP 9.2233
455 1M7G ADP 9.2233
456 1XMV ADP 9.2233
457 1XP8 AGS 9.2233
458 3F3E LEU 9.2233
459 1OYY AGS 9.2233
460 4ZDJ UTP 9.2233
461 2PZ8 APC 9.2233
462 1LVG ADP 9.59596
463 3T12 GDP ALF 9.59596
464 3T1O GDP 9.59596
465 1CS4 GSP 9.70874
466 5YT0 GDP 9.70874
467 2IXE ATP 9.70874
468 2BCG GDP 9.70874
469 2BIF SIN 9.70874
470 2BIF ANP 9.70874
471 1K6M AGS 9.70874
472 4ITR GDP 9.70874
473 1T3Q MCN 9.70874
474 3RWO GDP 9.72973
475 3IIJ ADP 10
476 1IHU ADP 10.1942
477 1IHU AF3 10.1942
478 2C78 GNP 10.1942
479 2C77 GNP 10.1942
480 1D8T GDP 10.1942
481 5UPK GNP 10.1942
482 2CK3 ADP 10.1942
483 3MD0 GDP 10.1942
484 1W0J ADP BEF 10.1942
485 2V7Q ADP 10.1942
486 2BVN GNP 10.1942
487 2V7Q ATP 10.1942
488 2CK3 ANP 10.1942
489 1W0J ADP 10.1942
490 1H65 GDP 10.1942
491 5MZN ADP 10.1942
492 1P4V GLY 10.1942
493 3MB5 SAM 10.1942
494 4V0K GDP 10.6509
495 3VX3 ADP 10.6796
496 1X1R GDP 10.6796
497 4LC1 GDP 10.6796
498 5FG3 GDP 10.6796
499 1OS1 ATP 10.6796
500 1OS1 PYR 10.6796
501 6F5W KG1 10.6796
502 1YZN GNP 10.8108
503 2CJW GDP 10.9375
504 1UPT GTP 11.1111
505 5X40 ACP 11.165
506 1G7C 5GP 11.165
507 4GOX A3P 11.165
508 5HR5 ADP 11.165
509 1MR3 G3D 11.6022
510 1ION ADP 11.6505
511 3ZQ6 ADP ALF 11.6505
512 3DEF GDP 11.6505
513 4ZG4 VO4 ADP 11.6505
514 4OI4 ATP 11.6505
515 3MAG SAH 11.6505
516 6AIC AMP 11.6822
517 2HT6 GDP 12.069
518 2RGX AP5 12.1359
519 5M04 GDP 12.1359
520 5N69 ADP 12.1359
521 1F9V ADP 12.1359
522 1Q19 SSC 12.1359
523 1QHG ATP 12.1359
524 5Y6Q MCN 12.3457
525 1FP6 ADP 12.6214
526 4WZA ACP 12.6214
527 4WZA ADP 12.6214
528 3HU3 AGS 12.6214
529 1NJF AGS 12.6214
530 4IEE AGS 12.6214
531 1U0J ADP 12.6214
532 1NJF ADP 12.6214
533 3ZIA ADP 12.6984
534 3ZIA ATP 12.6984
535 1R4A GNP 12.7273
536 3PQC GDP 12.8205
537 1SKQ GDP 13.1068
538 2J0V GDP 13.1068
539 5ZBC FAD 13.1068
540 5G3U FDA 13.1068
541 5G3U ITW 13.1068
542 3TBK ANP 13.1068
543 2HCJ GDP 13.5135
544 5UWQ GNP 13.5922
545 5UWP GNP 13.5922
546 5DHF GNP 13.5922
547 5UWR GNP 13.5922
548 5UWU GNP 13.5922
549 5UWH GNP 13.5922
550 5DIF GNP 13.5922
551 5UWJ GNP 13.5922
552 5UWW GNP 13.5922
553 5UWI GNP 13.5922
554 5UWO GNP 13.5922
555 6CIT GNP 13.5922
556 5UWT GNP 13.5922
557 5UWS GNP 13.5922
558 3GJ3 GDP 13.5922
559 5BXQ GDP 13.5922
560 3GJ0 GDP 13.5922
561 3QKT ANP 13.5922
562 3WXM GTP 13.5922
563 1IBR GNP 13.5922
564 5DI9 GNP 13.5922
565 3RC3 ANP 13.5922
566 1G3Q ADP 14.0777
567 3GJ7 GDP 14.0777
568 3GJ4 GDP 14.0777
569 3GJ5 GDP 14.0777
570 3GJ8 GDP 14.0777
571 4M9Q GNP 14.0777
572 1GOJ ADP 14.0777
573 1NY5 ADP 14.0777
574 3NRZ HPA 14.0777
575 1B0U ATP 14.5631
576 1OXV ANP 14.5631
577 2VWT PYR 14.5631
578 1W7J ADP BEF 14.5695
579 1QHH ATP 14.9701
580 2KIN ADP 15
581 1YTM ATP 15.0485
582 5O74 GDP 15.2284
583 6CRK GDP 15.493
584 1GP2 GDP 15.493
585 1RJ9 GCP 15.534
586 1WA5 GTP 15.9091
587 1LVK MNT BEF 16.0194
588 1NN5 ANP 16.0194
589 1NN5 2DT 16.0194
590 2A9K GDP 16.0428
591 2QN6 GDP 16.129
592 1J2J GTP 16.2651
593 1O3Y GTP 16.2651
594 3ZS9 ADP ALF 16.5049
595 2WOJ ADP ALF 16.5049
596 4XVU ATP 16.5049
597 4XTR ATP 16.5049
598 4XTR ADP 16.5049
599 1KAO GDP 16.5049
600 3EC1 GDP 16.5049
601 4IDN GNP 16.5049
602 4BAS GNP 16.5829
603 4HI0 GDP 16.5829
604 1F2U ATP 16.8919
605 4D0N GDP 16.9903
606 4BS0 6NT 16.9903
607 1KY3 GDP 17.033
608 1S9D GDP 17.0732
609 1RE0 GDP 17.0732
610 1UKZ ADP 17.2414
611 3CH5 GDP 17.3077
612 1U8Z GDP 17.8571
613 2WHX ADP 18.932
614 2JLR ANP 18.932
615 1DS6 GDP 19.4444
616 1Z0J GTP 20.339
617 4HAT GNP 20.8738
618 3M1I GTP 20.8738
619 2C5L GTP 21.3675
620 2PL3 ADP 21.8447
621 5BN3 ADP 23.7864
622 2FH5 GTP 24.8649
623 4LPS GDP 27.1845
624 5YGE ACO 28.1609
625 4BQS ADP 28.9773
626 4BQS K2Q 28.9773
627 2BEK ATP 30.0971
628 4IHQ ADP 40.7767
Pocket No.: 2; Query (leader) PDB : 4E03; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4e03.bio3) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4E03; Ligand: ADP; Similar sites found with APoc: 86
This union binding pocket(no: 3) in the query (biounit: 4e03.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 4ZCC FAD None
2 4NSQ COA None
3 4QC6 30N None
4 3RK1 ATP 0.970874
5 5BYK A3P 1.45631
6 5BYK OAQ 1.45631
7 4BUY F37 1.45631
8 1I1N SAH 1.45631
9 1E4E ADP 1.45631
10 5NWD 9C8 1.57068
11 3F8K COA 1.875
12 3TE4 ACO 1.94175
13 1RSG FAD 1.94175
14 3D9F FAD 1.94175
15 3D9F N6C 1.94175
16 1ZPD DPX 1.94175
17 3WR7 COA 2.35294
18 5FVJ ACO 2.40964
19 1BZY IMU 2.42718
20 6G96 ACO 2.84091
21 3G5N PB2 2.91262
22 1NST A3P 2.91262
23 2V58 LZJ 2.91262
24 4EUE NAI 2.91262
25 1VKJ A3P 2.91262
26 2VPQ ANP 2.91262
27 3UG4 AHR 3.39806
28 2VVL FAD 3.39806
29 2VVM FAD 3.39806
30 3R5W F42 3.57143
31 6EDV COA 3.60825
32 1ZX5 LFR 3.8835
33 2Q8M AMP 3.8835
34 1QPB TPP 3.8835
35 3FSM 2NC 3.94089
36 2FXV 5GP 4.12371
37 1I1D 16G 4.34783
38 1I1D COA 4.34783
39 5MPT SAH 4.36893
40 1XNG ATP 4.36893
41 4KVX ACO 4.48718
42 2MBR EPU 4.85437
43 2MBR FAD 4.85437
44 6FL8 ADP 4.85437
45 6FL8 TIY 4.85437
46 3R7F CP 4.85437
47 3MKH FAD 4.85437
48 2VBF TPP 4.85437
49 4TO8 FLC 5.33981
50 4R3L COA 5.78035
51 1QO8 FAD 5.82524
52 1H82 GZZ 6.79612
53 1H82 FAD 6.79612
54 2YNC YNC 6.79612
55 5EXE 5SR 6.79612
56 4GKV NAD 6.79612
57 1RM6 PCD 6.8323
58 2B4B COA 7.60234
59 2B4D COA 7.60234
60 2VHW NAI 7.76699
61 4AVB ACO 8.25243
62 1IZC PYR 8.25243
63 1P3D ANP 8.73786
64 4AUT FAD 9.70874
65 1JXZ BCA 9.70874
66 2VK4 TPP 11.165
67 1REO FAD 11.6505
68 3MCT SAH 11.6505
69 4CRZ ACO 11.8881
70 5GK9 ACO 12
71 1Q19 APC 12.1359
72 2Z49 AMG 13.1068
73 5JFL NAD 13.1068
74 2Z48 NGA 13.1068
75 4J56 FAD 13.1579
76 1FIQ MTE 14.0777
77 1FIQ SAL 14.0777
78 5UAV TFB 14.0777
79 5TS5 FAD 14.0777
80 5UAV NDP 14.0777
81 2R42 FPS 15.534
82 2C42 PYR 16.0194
83 2C42 TPP 16.0194
84 5LS7 ACO 16.6667
85 3D36 ADP 17.3913
86 5YGE GLU 28.1609
Pocket No.: 4; Query (leader) PDB : 4E03; Ligand: ADP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4e03.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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