Receptor
PDB id Resolution Class Description Source Keywords
4DMG 1.7 Å NON-ENZYME: OTHER THERMUS THERMOPHILUS M5C1942 METHYLTRANSFERASE RLMO THERMUS THERMOPHILUS RRNA METHYLTRANSFERASE S-ADENOSYL-METHIONINE 23S RIBOSOMATRANSFERASE
Ref.: IDENTIFICATION AND CHARACTERIZATION OF THE THERMUS THERMOPHILUS 5-METHYLCYTIDINE (M5C) METHYLTRANSFERA MODIFYING 23 S RIBOSOMAL RNA (RRNA) BASE C1942. J.BIOL.CHEM. V. 287 27593 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:401;
B:401;
Valid;
Valid;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4DMG 1.7 Å NON-ENZYME: OTHER THERMUS THERMOPHILUS M5C1942 METHYLTRANSFERASE RLMO THERMUS THERMOPHILUS RRNA METHYLTRANSFERASE S-ADENOSYL-METHIONINE 23S RIBOSOMATRANSFERASE
Ref.: IDENTIFICATION AND CHARACTERIZATION OF THE THERMUS THERMOPHILUS 5-METHYLCYTIDINE (M5C) METHYLTRANSFERA MODIFYING 23 S RIBOSOMAL RNA (RRNA) BASE C1942. J.BIOL.CHEM. V. 287 27593 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 4DMG - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 4DMG - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 4DMG - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4DMG; Ligand: SAM; Similar sites found: 625
This union binding pocket(no: 1) in the query (biounit: 4dmg.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5E9W SAH 0.0004896 0.45957 1.01781
2 2C7G ODP 0.04143 0.41206 1.01781
3 2C7G FAD 0.0426 0.41206 1.01781
4 4DSG FAD 0.003065 0.47554 1.27226
5 4DSG UDP 0.003065 0.47554 1.27226
6 4TXI FAD 0.002723 0.45359 1.27226
7 1JQ3 AAT 0.0001187 0.5226 1.35135
8 1OC2 NAD 0.01486 0.43641 1.43678
9 1OC2 TDX 0.01486 0.43641 1.43678
10 2IVD FAD 0.003236 0.45468 1.46444
11 1J0X NAD 0.04701 0.40189 1.50602
12 4KRG SAH 0.0000195 0.53257 1.52672
13 4REP FAD 0.001286 0.47829 1.52672
14 5T67 SAH 0.002634 0.46354 1.52672
15 5T67 JHZ 0.003277 0.46354 1.52672
16 3NDJ SAH 0.003609 0.46228 1.52672
17 3NDJ JHZ 0.003609 0.46228 1.52672
18 4G74 FAD 0.003576 0.45249 1.52672
19 4G74 UQ5 0.008348 0.44425 1.52672
20 4D04 NAP 0.02022 0.4332 1.52672
21 4D04 FAD 0.02022 0.4332 1.52672
22 5FJN BE2 0.01647 0.42727 1.52672
23 5FJN FAD 0.01469 0.42727 1.52672
24 2RGJ FAD 0.01661 0.41561 1.52672
25 4E70 N7I 0.002501 0.45276 1.54639
26 5F2K OCA 0.01188 0.42175 1.63043
27 5F2K SAH 0.01188 0.42175 1.63043
28 2B4R AES 0.02732 0.40136 1.73913
29 1Q9I TEO 0.001052 0.49781 1.78117
30 1Q9I FAD 0.001052 0.49781 1.78117
31 3HDY FDA 0.002261 0.48326 1.78117
32 3HDY GDU 0.002331 0.48326 1.78117
33 3HDY FAD 0.002776 0.47853 1.78117
34 4JDR FAD 0.002349 0.4671 1.78117
35 4UCI SAM 0.00102 0.45655 1.78117
36 1T9D FAD 0.004842 0.45007 1.78117
37 1T9D 1MM 0.01858 0.44394 1.78117
38 1T9D PYD 0.0182 0.44394 1.78117
39 1T9D P25 0.01989 0.44182 1.78117
40 5G3U ITW 0.01368 0.43061 1.78117
41 5G3U FDA 0.0114 0.42914 1.78117
42 4MIG G3F 0.02 0.42525 1.78117
43 5TTJ FAD 0.02057 0.41702 1.78117
44 1H9A NAP 0.02204 0.41052 1.78117
45 1ELI PYC 0.0129 0.42541 1.79949
46 2WA2 SAM 0.0002291 0.48258 1.81159
47 2PZM UDP 0.04512 0.40282 1.81818
48 2PZM NAD 0.04512 0.40282 1.81818
49 3PFG TLO 0.0002952 0.5119 1.90114
50 2A14 SAH 0.00359 0.43432 1.90114
51 1RKX NAD 0.01778 0.41184 1.96078
52 5MF6 7M2 0.0131 0.41845 1.98676
53 5MF6 AR6 0.0131 0.41845 1.98676
54 4NBU NAI 0.003091 0.44956 2
55 3GRU AMP 0.0003445 0.48492 2.0339
56 4JJF FE9 0.01112 0.41815 2.03488
57 4JJF N2I 0.01255 0.41815 2.03488
58 1UWK NAD 0.00009464 0.54288 2.03562
59 1UWK URO 0.00009464 0.54288 2.03562
60 1V59 FAD 0.0001791 0.52862 2.03562
61 1ZMD FAD 0.0007461 0.49465 2.03562
62 2NPX FAD 0.001533 0.47218 2.03562
63 2NPX NAD 0.00333 0.47218 2.03562
64 2X3N FAD 0.003977 0.45128 2.03562
65 1V59 NAD 0.001025 0.44487 2.03562
66 1ZMD NAI 0.00343 0.4402 2.03562
67 4J36 1HR 0.008773 0.43969 2.03562
68 1REO FAD 0.007708 0.43879 2.03562
69 4J36 FAD 0.006472 0.4361 2.03562
70 1Q1R FAD 0.009701 0.43169 2.03562
71 4K5S PM0 0.02122 0.42391 2.03562
72 4K5S FAD 0.01135 0.42391 2.03562
73 3CGB FAD 0.01434 0.42308 2.03562
74 1SC6 NAD 0.01573 0.41566 2.03562
75 3BXO SAM 0.00006534 0.50258 2.09205
76 2Q1W NAD 0.01822 0.41248 2.1021
77 3GU3 SAH 0.00002035 0.51182 2.11268
78 3U4C NDP 0.003646 0.44331 2.13523
79 3CBG SAH 0.00002192 0.53019 2.15517
80 3CTY FAD 0.006088 0.44876 2.19436
81 3RIY NAD 0.004727 0.43912 2.1978
82 2V6G NAP 0.02999 0.40049 2.1978
83 3QWI CUE 0.04772 0.40074 2.22222
84 3QWI NAP 0.03347 0.40029 2.22222
85 3CIF NAD 0.02334 0.40355 2.22841
86 3CIF G3H 0.0317 0.40355 2.22841
87 4ONQ SFG 0.000262 0.48221 2.2409
88 5BW4 SAM 0.000155 0.4905 2.24719
89 1FL2 FAD 0.03197 0.40719 2.25806
90 1Y8Q ATP 0.0003479 0.48659 2.29008
91 1YQZ FAD 0.002608 0.47852 2.29008
92 1ZK7 FAD 0.001781 0.4772 2.29008
93 3NTA FAD 0.002107 0.46632 2.29008
94 3LXD FAD 0.001894 0.4652 2.29008
95 4D7E FAD 0.002969 0.45656 2.29008
96 3MJE NDP 0.002645 0.45156 2.29008
97 3NT6 FAD 0.005926 0.44357 2.29008
98 4BJZ P3A 0.01677 0.44168 2.29008
99 4IV9 FAD 0.007313 0.44094 2.29008
100 3CGD FAD 0.02341 0.43694 2.29008
101 3CGD NAD 0.02341 0.43694 2.29008
102 3CGD COA 0.02341 0.43694 2.29008
103 4X9M FAD 0.009526 0.43507 2.29008
104 4AT0 FAD 0.02927 0.41581 2.29008
105 3MQ2 SAH 0.0005292 0.46559 2.29358
106 2O07 MTA 0.00007784 0.52356 2.30263
107 2O07 SPD 0.00009472 0.52279 2.30263
108 3WGT FAD 0.007261 0.4474 2.30548
109 3WGT QSC 0.00753 0.4474 2.30548
110 4OBW SAM 0.0001068 0.50052 2.33463
111 3KLJ FAD 0.002115 0.46032 2.33766
112 2XMY CDK 0.03426 0.42027 2.34899
113 3MB5 SAM 0.00006313 0.52031 2.35294
114 1EFV FAD 0.00216 0.48135 2.35294
115 1EFV AMP 0.00216 0.48135 2.35294
116 2WSB NAD 0.002683 0.46313 2.3622
117 2WK1 SAH 0.0005093 0.47288 2.48227
118 5FA8 SAM 0.000006381 0.56809 2.48447
119 4USQ FAD 0.009254 0.42948 2.49307
120 2FK8 SAM 0.007305 0.41785 2.51572
121 1BDB NAD 0.001307 0.47075 2.52708
122 4K26 NDP 0.01731 0.41242 2.53623
123 4K26 SFF 0.0319 0.40723 2.53623
124 2HQM FAD 0.001184 0.48333 2.54453
125 1PN0 FAD 0.002798 0.46889 2.54453
126 1PN0 IPH 0.002908 0.46889 2.54453
127 4BV6 FAD 0.004373 0.45332 2.54453
128 3LU1 NAD 0.004797 0.43881 2.54453
129 5TUF TDC 0.01822 0.43373 2.54453
130 5JWC FAD 0.01121 0.42641 2.54453
131 1N4W FAD 0.01632 0.42579 2.54453
132 5TUF FAD 0.01309 0.41965 2.54453
133 1GY8 NAD 0.02164 0.40758 2.54453
134 3LCC SAH 0.0001002 0.49935 2.55319
135 4X7Y SAH 0.0009982 0.48607 2.55474
136 3GF4 FAD 0.006441 0.45485 2.5641
137 3GF4 UPG 0.009365 0.44842 2.5641
138 5X20 NAD 0.01428 0.41007 2.5641
139 2EFJ SAH 0.0005084 0.4664 2.60417
140 2GN4 NDP 0.01434 0.45693 2.61628
141 2GN4 UD1 0.0186 0.45182 2.61628
142 1IY8 NAD 0.004025 0.44388 2.62172
143 1VL8 NAP 0.02006 0.4115 2.62172
144 5DY5 5GR 0.02174 0.43027 2.63158
145 4NEC SAH 0.00001224 0.53915 2.65152
146 1Z3C SA8 0.001179 0.46885 2.68456
147 2Z3Y F2N 0.001237 0.48339 2.71903
148 3O7W SAM 0.0009307 0.44937 2.72109
149 5FTW SAH 0.00007603 0.51215 2.73438
150 4BLW SAH 0.00001668 0.55431 2.76817
151 4BLW AMP 0.00006775 0.53623 2.76817
152 4J7U YTZ 0.02742 0.41327 2.77778
153 4J7U NAP 0.02742 0.41327 2.77778
154 3CH6 NAP 0.01183 0.44503 2.7972
155 3CH6 311 0.01183 0.44503 2.7972
156 4M52 FAD 0.000949 0.48825 2.79898
157 1BZL FAD 0.004039 0.48576 2.79898
158 3SQP FAD 0.01005 0.48117 2.79898
159 2A8X FAD 0.002568 0.46711 2.79898
160 2RAB FAD 0.002761 0.46645 2.79898
161 2RAB NAD 0.005251 0.46645 2.79898
162 5JAQ NAI 0.002415 0.4644 2.79898
163 4N49 SAM 0.0009224 0.46062 2.79898
164 2C31 TZD 0.00959 0.45539 2.79898
165 2C31 ADP 0.009359 0.45539 2.79898
166 4C3Y FAD 0.008107 0.43961 2.79898
167 4C3Y ANB 0.01052 0.43821 2.79898
168 5M67 NAD 0.01431 0.43286 2.79898
169 5M67 ADE 0.01585 0.43054 2.79898
170 2ZXI FAD 0.01062 0.4297 2.79898
171 5M67 3D1 0.01754 0.42823 2.79898
172 3FWN ATR 0.02552 0.4073 2.79898
173 1ZQ9 SAM 0.000582 0.46592 2.80702
174 3NUG NAD 0.007191 0.43139 2.83401
175 1Z6Z NAP 0.01097 0.42105 2.83688
176 3GGO NAI 0.02973 0.41059 2.86624
177 3GGO ENO 0.02973 0.41059 2.86624
178 2BD0 NAP 0.005786 0.43732 2.86885
179 1PR9 NAP 0.01761 0.41434 2.86885
180 3D3W NAP 0.01792 0.41396 2.86885
181 3TKA SAM 0.000002833 0.58005 2.88184
182 2RH4 EMO 0.02879 0.41464 2.88809
183 4D3F NAP 0.01325 0.40713 2.90323
184 4M37 SAH 0.0007217 0.46365 2.91545
185 4GLL NAD 0.01078 0.42386 2.96736
186 1CF2 NAP 0.01061 0.41779 2.96736
187 1XCL SAH 0.0003187 0.49983 2.97872
188 1XHC FAD 0.001228 0.47584 2.99728
189 1DXY NAD 0.01094 0.41713 3.003
190 3P9C SAH 0.003096 0.45082 3.02198
191 1X87 NAD 0.00002237 0.54194 3.05344
192 5WGR FAD 0.001196 0.481 3.05344
193 2Q7V FAD 0.004197 0.45423 3.05344
194 1PS9 FAD 0.006457 0.44467 3.05344
195 1RSG FAD 0.006904 0.44412 3.05344
196 3OZ2 FAD 0.009996 0.43401 3.05344
197 1YY5 FAD 0.01253 0.43258 3.05344
198 3GMB FAD 0.01088 0.42596 3.05344
199 2B9W FAD 0.02631 0.42325 3.05344
200 3BGD PM6 0.0001962 0.50394 3.07692
201 3BGD SAH 0.0001384 0.50394 3.07692
202 2ZAT NAP 0.02608 0.40236 3.07692
203 1L1E SAH 0.004173 0.42943 3.13589
204 1XTP SAI 0.0007809 0.45991 3.14961
205 3ZV6 NAD 0.001384 0.47883 3.20285
206 3ZV6 4HB 0.00145 0.47883 3.20285
207 2G5C NAD 0.02461 0.40362 3.20285
208 3VC1 GST 0.001312 0.47896 3.20513
209 3VC1 SAH 0.001312 0.47896 3.20513
210 3S5W FAD 0.0006498 0.48306 3.23974
211 4FC7 NAP 0.02633 0.41418 3.2491
212 4FC7 COA 0.02633 0.41418 3.2491
213 2ZFU SAH 0.0005943 0.4697 3.25581
214 1R6D NAD 0.0278 0.42062 3.2641
215 1R6D DAU 0.04568 0.40845 3.2641
216 3V1Y NAD 0.0217 0.40255 3.2641
217 1KYZ SAH 0.004024 0.42641 3.28767
218 1KYZ FER 0.0111 0.4182 3.28767
219 4PLG NAI 0.03414 0.40386 3.29341
220 1DL5 SAH 0.0001164 0.51326 3.30789
221 5JJR SAH 0.0001041 0.50105 3.30789
222 2CDU FAD 0.001651 0.46938 3.30789
223 4U8P FDA 0.004986 0.46829 3.30789
224 4U8P UDP 0.005258 0.46829 3.30789
225 5BR7 FLC 0.005442 0.46299 3.30789
226 5BR7 FAD 0.005442 0.46299 3.30789
227 2IXB NAD 0.00681 0.43256 3.30789
228 2IXB A2G 0.009764 0.43256 3.30789
229 3AXB FAD 0.01714 0.41915 3.30789
230 3AXB PRO 0.02111 0.41915 3.30789
231 2CDU ADP 0.008051 0.41028 3.30789
232 1O97 AMP 0.00295 0.47345 3.40909
233 1O97 FAD 0.00295 0.47345 3.40909
234 2O4C NAD 0.02819 0.40183 3.42105
235 2A92 NAI 0.01936 0.41116 3.42679
236 3U31 NAD 0.003355 0.43573 3.44828
237 1NFQ NAI 0.01083 0.42377 3.46154
238 4RDH AMP 0.001302 0.44504 3.47222
239 4RDI ATP 0.002157 0.43916 3.47222
240 1OAA OAA 0.03173 0.41081 3.4749
241 1GEG NAD 0.005946 0.4342 3.51562
242 1P1C SAH 0.0003424 0.48505 3.51759
243 4X60 SFG 0.0001539 0.52506 3.56234
244 4X60 3XV 0.0001627 0.52506 3.56234
245 3X0D SAH 0.000184 0.49172 3.56234
246 2XVE FAD 0.004338 0.46753 3.56234
247 2XVF FAD 0.002073 0.46556 3.56234
248 5BUK FAD 0.003567 0.46073 3.56234
249 5MBX FAD 0.00787 0.45027 3.56234
250 5MBX SP5 0.00787 0.45027 3.56234
251 3NJ4 NAD 0.03126 0.4424 3.56234
252 3NJ4 AFX 0.03257 0.44138 3.56234
253 1GTE FAD 0.01809 0.43454 3.56234
254 2RGO FAD 0.01072 0.4295 3.56234
255 4USR FAD 0.01481 0.41812 3.56234
256 2X24 X24 0.01161 0.40471 3.56234
257 1LSS NAD 0.00008806 0.50911 3.57143
258 1U1I NAD 0.02322 0.40937 3.57143
259 2BGM NAJ 0.005383 0.43219 3.59712
260 2CFC NAD 0.02359 0.40332 3.6
261 1DSS NAD 0.01494 0.40912 3.6036
262 3EVF SAH 0.0003348 0.50423 3.61011
263 3EVF GTA 0.0003964 0.50423 3.61011
264 3AB1 FAD 0.01554 0.42419 3.61111
265 3G89 SAM 0.0001063 0.49284 3.61446
266 4D79 ATP 0.001597 0.4453 3.62319
267 4KIB SAH 0.000001208 0.589 3.64146
268 2VDV SAM 0.00004584 0.496 3.65854
269 3ELW SAM 0.0002892 0.51351 3.66667
270 3ELW GP3 0.0003067 0.51334 3.66667
271 4A6D SAM 0.0004694 0.47249 3.68272
272 2EJU SAH 0.0000005143 0.60945 3.7037
273 4PIO SAH 0.0001925 0.51358 3.71517
274 4PIO AVI 0.0001912 0.51231 3.71517
275 4TQG NDP 0.001932 0.45686 3.71517
276 5ULP KB1 0.00003057 0.53753 3.73134
277 5DLY 5D7 0.0009878 0.48411 3.7594
278 5DLY SAH 0.000889 0.48411 3.7594
279 3TKY SAH 0.0006055 0.46726 3.80435
280 5JGL SAM 0.0008332 0.45637 3.80623
281 4C4A SAH 0.00009592 0.50509 3.81679
282 1V5F FAD 0.001457 0.49484 3.81679
283 4OPC PGT 0.004349 0.48758 3.81679
284 4OPC FDA 0.003963 0.48669 3.81679
285 1YBH FAD 0.002432 0.46425 3.81679
286 3OND ADN 0.01789 0.42701 3.81679
287 3OND NAD 0.01789 0.42701 3.81679
288 3UOY NAP 0.0358 0.42212 3.81679
289 3UOY FAD 0.0358 0.42212 3.81679
290 1V8B NAD 0.01918 0.41566 3.81679
291 4M73 SAH 0.00002123 0.56443 3.85757
292 4M73 M72 0.00002577 0.56164 3.85757
293 5GWX SAR 0.002479 0.4486 3.87324
294 5GWX SAM 0.002479 0.4486 3.87324
295 1KEW TYD 0.03864 0.41093 3.87812
296 4FN4 NAD 0.003666 0.44456 3.93701
297 2C5A NAD 0.008078 0.44893 3.95778
298 2C5A GDC 0.008078 0.44893 3.95778
299 2Q1S NAI 0.04908 0.4009 3.97878
300 3AYI FAD 0.01089 0.44137 4.02219
301 3AYI HCI 0.01125 0.44137 4.02219
302 5E72 SAM 0.0000003928 0.62357 4.04624
303 3ZG6 APR 0.008479 0.41476 4.05405
304 2AG5 NAD 0.01507 0.41421 4.06504
305 3NTD FAD 0.001565 0.47286 4.0708
306 5BVA FAD 0.000537 0.50302 4.07125
307 4KGD TDP 0.002295 0.487 4.07125
308 4KGD FAD 0.00236 0.487 4.07125
309 5L95 AMP 0.001363 0.45059 4.07125
310 4ITU NAI 0.007735 0.43223 4.07125
311 4ITU 1HS 0.01176 0.43223 4.07125
312 4YNU FAD 0.01925 0.42293 4.07125
313 4YNU LGC 0.02215 0.42293 4.07125
314 1COY FAD 0.02651 0.41316 4.07125
315 3ABI NAD 0.002003 0.45751 4.10959
316 3OU2 SAH 0.000933 0.46763 4.12844
317 3DXY SAM 0.0004833 0.45982 4.12844
318 1UDB NAD 0.0221 0.42447 4.14201
319 2YY7 NAD 0.01617 0.41391 4.16667
320 1WVG APR 0.01582 0.4079 4.17827
321 3WDM ADN 0.02309 0.40842 4.21456
322 3I53 SAH 0.0007218 0.46569 4.21687
323 3LZW NAP 0.01243 0.4419 4.21687
324 3LZW FAD 0.008677 0.43517 4.21687
325 1Q0S SAH 0.000000632 0.61878 4.2471
326 4D42 NAP 0.02491 0.421 4.25532
327 4D42 W0I 0.02491 0.421 4.25532
328 1SB8 NAD 0.01003 0.44012 4.26136
329 1SB8 UD2 0.0115 0.44012 4.26136
330 2DT5 NAD 0.004011 0.44128 4.2654
331 1I9G SAM 0.00008023 0.51103 4.28571
332 2EG5 SAH 0.0002333 0.47709 4.30108
333 1N2X SAM 0.0000163 0.54854 4.31894
334 1F3L SAH 0.0001628 0.49854 4.3257
335 1MO9 KPC 0.007677 0.46447 4.3257
336 1MO9 FAD 0.007619 0.46411 4.3257
337 3SSO SAH 0.0007888 0.46385 4.3257
338 4YRY FAD 0.01281 0.43033 4.3257
339 4YRY NAD 0.02509 0.42298 4.3257
340 2ZJ1 ARJ 0.02487 0.42177 4.3257
341 2ZJ1 NAD 0.0342 0.41445 4.3257
342 4QTU SAM 0.0004377 0.47392 4.32692
343 1I8T FAD 0.009849 0.43337 4.35967
344 3EVG SAH 0.00008542 0.50509 4.36364
345 1ZGA SAH 0.003666 0.42189 4.48179
346 2OBF F83 0.01866 0.42191 4.49827
347 2OBF SAH 0.01866 0.42191 4.49827
348 1TPY SAH 0.003959 0.43229 4.52962
349 2DTX BMA 0.01109 0.43074 4.54545
350 3QJ4 FAD 0.004639 0.44896 4.58015
351 5DNK SAH 0.00124 0.43401 4.58015
352 2QA1 FAD 0.008911 0.43142 4.58015
353 1ZEM NAD 0.007768 0.42441 4.58015
354 4XUC 43G 0.00002119 0.56144 4.58716
355 4XUC SAM 0.00002119 0.56144 4.58716
356 1G60 SAM 0.00001443 0.54397 4.61538
357 2PWY SAH 0.00005592 0.52284 4.65116
358 2B4Q NAP 0.01225 0.41868 4.71014
359 5KOK S9T 0.0005276 0.49171 4.78589
360 5KOK SAH 0.0008033 0.46145 4.78589
361 5KOK R9T 0.003121 0.45191 4.78589
362 1XDS SAM 0.003283 0.4241 4.81283
363 1QZZ SAM 0.006675 0.40986 4.81283
364 4DCM SAM 0.000002112 0.57457 4.83461
365 4FZV SAM 0.00002089 0.53881 4.83461
366 1U2Z SAH 0.0001657 0.50019 4.83461
367 5U8U FAD 0.00166 0.49252 4.83461
368 2GSD NAD 0.01144 0.42595 4.83461
369 1O94 ADP 0.01629 0.40585 4.83461
370 1UP7 NAD 0.019 0.40402 4.83461
371 1DJN ADP 0.01678 0.40374 4.83461
372 1FP1 SAH 0.0008826 0.45288 4.83871
373 5JE0 AZ8 0.0001459 0.51512 4.8583
374 5JE0 SAH 0.0001459 0.51512 4.8583
375 1I1N SAH 0.000008817 0.56978 4.86726
376 3LST SAH 0.00255 0.42917 4.88506
377 1QAN SAH 0.00011 0.50667 4.91803
378 1T26 NAI 0.01524 0.42644 4.96894
379 3NYC FAD 0.007072 0.45043 4.98688
380 3NYC IAR 0.007072 0.45043 4.98688
381 3A4V PYR 0.02759 0.40762 5.04732
382 3A4V NAD 0.02759 0.40762 5.04732
383 1XSE NDP 0.009327 0.43554 5.08475
384 3LAD FAD 0.0005632 0.49984 5.08906
385 2NVK FAD 0.004435 0.45301 5.08906
386 4J4H NAI 0.008074 0.44417 5.08906
387 4J4H 1J1 0.008074 0.44417 5.08906
388 4JK3 NAD 0.003856 0.43925 5.08906
389 2NAD NAD 0.01267 0.42372 5.08906
390 1JG3 ADN 0.00001514 0.54041 5.10638
391 1BC5 SAH 0.001586 0.45308 5.20446
392 2DPM SAM 0.0000002432 0.63352 5.28169
393 3EYA FAD 0.0009199 0.48092 5.34351
394 3ICT FAD 0.002275 0.46352 5.34351
395 3ICS FAD 0.00286 0.4596 5.34351
396 3ICR FAD 0.003077 0.4569 5.34351
397 3UCL NAP 0.01177 0.44884 5.34351
398 3UCL CYH 0.01089 0.44884 5.34351
399 3UCL FAD 0.01089 0.44884 5.34351
400 4J56 FAD 0.01299 0.43177 5.34351
401 2V3A FAD 0.01963 0.41712 5.34351
402 2V3B FAD 0.02837 0.40799 5.34351
403 1UAY ADN 0.003022 0.42576 5.3719
404 5KVA SAM 0.0001317 0.50294 5.39568
405 1FP2 SAH 0.00441 0.44677 5.39773
406 3H2B SAH 0.0007653 0.46245 5.41872
407 1GR0 NAD 0.001707 0.46623 5.44959
408 3H8V ATP 0.002123 0.43949 5.47945
409 5MGZ SAH 0.0001114 0.50201 5.50847
410 3C6K MTA 0.0002894 0.50741 5.51181
411 3C6K SPD 0.0002894 0.50741 5.51181
412 3FRH SAH 0.002026 0.44797 5.5336
413 4YAG NAI 0.001706 0.47522 5.53633
414 3OFK SAH 0.005514 0.4254 5.55556
415 2VT3 ATP 0.003367 0.4212 5.5814
416 3T7S SAM 0.0001375 0.49538 5.59701
417 4KRI SAH 0.0002845 0.4849 5.59796
418 4RPL 3UC 0.003129 0.47914 5.59796
419 4RPL FAD 0.003972 0.47162 5.59796
420 4XQC NAD 0.01451 0.42842 5.59796
421 4XQC 13D 0.01763 0.42491 5.59796
422 4J1Q NDP 0.008717 0.42335 5.59796
423 2GDZ NAD 0.003671 0.44453 5.61798
424 5J60 FAD 0.007936 0.43913 5.625
425 5M58 SAH 0.0001206 0.50039 5.65217
426 2JAH NDP 0.01453 0.41621 5.66802
427 2JAP NDP 0.01472 0.41593 5.66802
428 5XLX SAH 0.01131 0.40524 5.67376
429 3LCV SAM 0.005837 0.42587 5.69395
430 2XYQ SAH 0.0004528 0.47104 5.7377
431 1E3W NAD 0.01165 0.41976 5.74713
432 4NBW NAD 0.009641 0.4212 5.83658
433 1FEC FAD 0.002669 0.46906 5.85242
434 5F8F SFG 0.0005143 0.46377 5.85242
435 4EMI NAD 0.00584 0.46068 5.85242
436 4EMI FAD 0.002723 0.46068 5.85242
437 4AP3 FAD 0.0106 0.44691 5.85242
438 4AP3 NAP 0.0106 0.44691 5.85242
439 4FWE FAD 0.01103 0.43457 5.85242
440 4GUT FAD 0.01247 0.43436 5.85242
441 4HSU FAD 0.01218 0.43323 5.85242
442 4GUS FAD 0.01304 0.43169 5.85242
443 3SJU NDP 0.01564 0.41463 5.85242
444 1Z45 NAD 0.02327 0.40483 5.85242
445 3LKZ SFG 0.0001174 0.50094 5.919
446 4I5I NAD 0.01133 0.41775 5.92335
447 4LWP SAH 0.00009739 0.50241 5.97826
448 4MOP 2H5 0.03101 0.41741 6.00316
449 1XKQ NDP 0.007045 0.43426 6.07143
450 5GT9 NAP 0.02373 0.40558 6.08365
451 1E1M FAD 0.00994 0.4442 6.08696
452 1E1M NAP 0.00994 0.4442 6.08696
453 1XG5 NAP 0.007133 0.43156 6.09319
454 3S1S SAH 0.0001813 0.49831 6.10687
455 2ZWA SAH 0.001622 0.45083 6.10687
456 1G8K MGD 0.03046 0.4064 6.10687
457 1ORR NAD 0.02772 0.40442 6.10687
458 2YYY NAP 0.0196 0.40732 6.12245
459 2AE2 PTO 0.03279 0.40752 6.15385
460 2AE2 NAP 0.03279 0.40752 6.15385
461 3P2E SAH 0.00001745 0.54252 6.22222
462 1NW5 SAM 0.00000179 0.58682 6.26959
463 1S7G APR 0.005162 0.441 6.32411
464 1S7G NAD 0.005066 0.43893 6.32411
465 3H9E NAD 0.02095 0.4033 6.35838
466 3QOX SAH 0.00005906 0.5217 6.36132
467 5MW4 5JU 0.0002137 0.51904 6.36132
468 5X62 SAH 0.0002097 0.48437 6.36132
469 3E1T FAD 0.002716 0.46586 6.36132
470 4EUE NAI 0.002583 0.45473 6.36132
471 2VVL FAD 0.01315 0.42885 6.36132
472 2VVM FAD 0.01632 0.42312 6.36132
473 1O5I NAD 0.01049 0.40861 6.4257
474 4NTD FAD 0.002654 0.46125 6.47059
475 4POO SAM 0.0003151 0.48867 6.5
476 4R6W PC 0.002571 0.4742 6.58915
477 4R6W SAH 0.001162 0.47196 6.58915
478 3PT9 SAH 0.00001811 0.53675 6.61578
479 3TLJ SAH 0.00005182 0.52442 6.61578
480 1D4D FAD 0.0005885 0.49993 6.61578
481 2Q28 ADP 0.0007226 0.46363 6.61578
482 1PJS NAD 0.01124 0.40347 6.61578
483 5N5D SAM 0.0000152 0.5429 6.63717
484 3GDH SAH 0.0000008189 0.61335 6.639
485 5DM1 5D7 0.0005688 0.49627 6.74157
486 5DM1 SAH 0.0006511 0.49213 6.74157
487 4MO2 FDA 0.008507 0.43457 6.79348
488 4MO2 FAD 0.01389 0.42478 6.79348
489 5DX1 SFG 0.000184 0.50179 6.87023
490 5DWQ SFG 0.0002172 0.49646 6.87023
491 5DX8 SFG 0.0002527 0.49139 6.87023
492 5DX0 SFG 0.0003186 0.49024 6.87023
493 5DXA SFG 0.0002867 0.48876 6.87023
494 2BZG SAH 0.0001262 0.49712 6.89655
495 1U7T TDT 0.01784 0.42204 6.89655
496 1U7T NAD 0.02038 0.4052 6.89655
497 5GM1 SAH 0.0007624 0.46836 7.07071
498 3DAG FEG 0.01389 0.41067 7.26257
499 4AZT SAM 0.00004776 0.51696 7.37913
500 3GD4 FAD 0.006764 0.43962 7.37913
501 5ITV NAI 0.0108 0.42262 7.45098
502 2WPF FAD 0.003758 0.48702 7.63359
503 2WPF WPF 0.00704 0.47329 7.63359
504 1RJD SAM 0.002547 0.43964 7.63359
505 1ZBQ NAD 0.01331 0.4193 7.64526
506 1KYQ NAD 0.003072 0.42987 7.66423
507 3EGI ADP 0.000004358 0.51724 7.76699
508 3TN7 NJP 0.01775 0.41188 7.7821
509 2PX8 SAH 0.0004647 0.47051 7.80669
510 2F5Z FAD 0.0008772 0.49104 7.8125
511 4XZ3 COA 0.01098 0.41264 7.82609
512 4XYM COA 0.02833 0.41167 7.82609
513 1NVM NAD 0.03065 0.40222 7.82609
514 4IWN GEK 0.00000393 0.57819 7.86026
515 3RFV NAI 0.0152 0.41148 7.86517
516 3RFV 15L 0.01662 0.40824 7.86517
517 2AOT SAH 0.0027 0.43032 7.87671
518 1JQD SAH 0.008879 0.42559 7.87671
519 3G5S FAD 0.01217 0.4267 7.88804
520 2Y6Q I7T 0.02565 0.41805 7.88804
521 2Y6Q FAD 0.0141 0.41805 7.88804
522 3B1F NAD 0.01236 0.40858 7.93103
523 4YSX FAD 0.02318 0.41528 7.97872
524 3ZNN FAD 0.02876 0.42185 8.06916
525 3ZNN 4WL 0.02876 0.42185 8.06916
526 1KPG SAH 0.00372 0.43359 8.14249
527 2HMT NAI 0.0008573 0.46406 8.33333
528 1NM5 NAP 0.01302 0.43655 8.37438
529 1NM5 NAD 0.01345 0.43655 8.37438
530 2GMH FAD 0.0176 0.42234 8.39695
531 2ZIF SAM 0.000003606 0.57244 8.41751
532 1E6E FAD 0.004545 0.44725 8.59375
533 3RNM FAD 0.001507 0.47899 8.62069
534 4ZCC NAI 0.007074 0.45042 8.63095
535 4ZCC FAD 0.007074 0.45042 8.63095
536 1KPH SAH 0.004048 0.43183 8.6514
537 5E1M SAH 0.001028 0.47723 8.71369
538 5E1M PRO PRO LYS ARG ILE ALA 0.001028 0.47723 8.71369
539 1XHL NDP 0.001667 0.46417 8.75421
540 3Q9T FAY 0.03983 0.40135 8.90585
541 5CUQ NSC 0.0001488 0.51623 8.98876
542 1SQF SAM 0.000003352 0.57119 9.16031
543 5L13 6ZE 0.04037 0.41062 9.16031
544 2BFR ADP 0.01392 0.40767 9.16031
545 2HNK SAH 0.0000604 0.51689 9.20502
546 1G55 SAH 0.00001401 0.54458 9.32945
547 5ODQ FAD 0.01165 0.43246 9.36455
548 1PNO NAP 0.005053 0.43769 9.44444
549 5XVK SAH 0.002238 0.4459 9.50704
550 1DJL NAP 0.005987 0.43779 9.66184
551 2JJQ SAH 0.00000002507 0.6601 9.66921
552 1GZ6 NAI 0.02242 0.40682 9.71787
553 2OOR TXP 0.004113 0.43934 9.77011
554 3DUW SAH 0.00002788 0.53046 9.86547
555 5LOG SAH 0.00006195 0.51406 9.92366
556 3FG2 FAD 0.006937 0.4346 9.92366
557 2YVJ FAD 0.004893 0.44673 10.0917
558 1R18 SAH 0.000005669 0.56819 10.1322
559 1YC5 NCA 0.00242 0.45061 10.1626
560 4BUZ NAD 0.005743 0.43224 10.1626
561 4BUZ OCZ 0.006914 0.43224 10.1626
562 4BUZ OAD 0.006914 0.43224 10.1626
563 1LVL FAD 0.00585 0.44875 10.1781
564 5I39 FAD 0.00704 0.43978 10.1781
565 3NKS FAD 0.009614 0.43188 10.1781
566 1LVL NAD 0.003889 0.43089 10.1781
567 1KNR FAD 0.01976 0.41885 10.1781
568 5K8V 6RE 0.0004666 0.5147 10.2493
569 5MPT SAH 0.0009968 0.45493 10.4326
570 2EWM NAD 0.009254 0.42595 10.4418
571 3C3Y SAH 0.00005311 0.51722 10.5485
572 1WY7 SAH 0.00002801 0.53505 10.628
573 3GCZ SAM 0.00009132 0.50373 10.6383
574 1IM8 SAI 0.000007836 0.55905 10.6557
575 1EDO NAP 0.01471 0.41712 10.6557
576 1GET FAD 0.002484 0.48385 10.6667
577 1GET NAP 0.002628 0.48385 10.6667
578 5K7U SAM 0.0005642 0.46655 10.6667
579 3HVJ 705 0.00002758 0.56016 10.8597
580 2PT9 S4M 0.00008645 0.51769 10.9415
581 2PT9 2MH 0.0001593 0.51769 10.9415
582 4PNE SAH 0.001656 0.45218 10.9415
583 2GAG NAD 0.003326 0.45519 11.1111
584 2DKH FAD 0.006782 0.43509 11.1959
585 2DKH 3HB 0.009112 0.43509 11.1959
586 5IL1 SAM 0.0005068 0.46874 11.3208
587 4Y2H SAH 0.0007955 0.48888 11.3636
588 4Y2H 49K 0.00113 0.48114 11.3636
589 1RYI FAD 0.03347 0.40792 11.4504
590 2P41 SAH 0.0001344 0.49583 11.4754
591 3WMX NAD 0.02441 0.40259 11.7318
592 4RVG SAM 0.006112 0.44589 12.2137
593 4RVG TYD 0.006649 0.44589 12.2137
594 3GEG NAD 0.0004641 0.48567 12.5506
595 1EJ0 SAM 0.0006265 0.46441 13.3333
596 3FUU ADN 0.0003629 0.47777 13.6531
597 4CNK FAD 0.02784 0.40935 13.7405
598 1D4O NAP 0.005313 0.43246 14.1304
599 2NXE SAM 0.00008327 0.50561 14.5669
600 3EGV SAH 0.00008905 0.50175 14.5669
601 4YMH SAH 0.00004888 0.52126 15
602 1WG8 SAM 0.000009547 0.56191 15.0877
603 2I7C AAT 0.0001497 0.51759 15.1943
604 5XVQ SAH 0.002216 0.4461 15.5216
605 5E8J SAH 0.0005398 0.46028 15.9091
606 5HJM MTA 0.0000000712 0.65301 16.1932
607 3M6W SAM 0.001421 0.44327 16.285
608 1M2K APR 0.003445 0.44311 16.4659
609 1L3I SAH 0.00001603 0.55515 16.6667
610 3AD8 NAD 0.001924 0.46363 16.7488
611 3DMH GMP 0.00002443 0.54815 16.7979
612 3DMH SAM 0.00001745 0.54252 16.7979
613 4YUW S4M 0.001708 0.50838 17.1053
614 4YUW 4JU 0.001742 0.50838 17.1053
615 1QO8 FAD 0.004073 0.45587 18.8295
616 2CUL FAD 0.02998 0.40478 18.9655
617 4CQM NAP 0.009783 0.42351 19.084
618 4II2 ATP 0.0005849 0.47003 19.2771
619 1NV8 MEQ 0.000004725 0.58301 20.8651
620 1NV8 SAM 0.000005185 0.58301 20.8651
621 3A4T SFG 0.0003254 0.48417 24.8175
622 5FA5 MTA 0.0003055 0.47428 25
623 4GQB 0XU 0.00003171 0.53676 27.2727
624 4M38 SAH 0.0006609 0.4675 28.5714
625 4KXQ APR 0.004677 0.42883 30
Pocket No.: 2; Query (leader) PDB : 4DMG; Ligand: SAM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4dmg.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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