Receptor
PDB id Resolution Class Description Source Keywords
4DFX 1.35 Å EC: 2.7.11.11 CRYSTAL STRUCTURE OF MYRISTOYLATED K7C CATALYTIC SUBUNIT OF DEPENDENT PROTEIN KINASE IN COMPLEX WITH SP20 AND AMP-PNP MUS MUSCULUS PROTEIN KINASE MYRISTOYLATED PHOSPHOTRANSFERASE ONTO SER/TPKI PKA REGULATORY SUBUNITS PHOSPHORYLATED ON S139 T197MYRISTOYLATED ON G1 TRANSFERASE TRANSFERASE-TRANSFERASE ICOMPLEX
Ref.: ROLE OF N-TERMINAL MYRISTYLATION IN THE STRUCTURE A REGULATION OF CAMP-DEPENDENT PROTEIN KINASE. J.MOL.BIOL. V. 422 215 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP E:402;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
GOL E:405;
E:406;
E:407;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MG E:403;
E:404;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
MYR E:401;
Invalid;
none;
submit data
228.371 C14 H28 O2 CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2GU8 2.2 Å EC: 2.7.11.11 DISCOVERY OF 2-PYRIMIDYL-5-AMIDOTHIOPHENES AS NOVEL AND POTENT INHIBITORS FOR AKT: SYNTHESIS AND SAR STUDIES HOMO SAPIENS CAMP-DEPENDENT PROTEIN KINASE PKA AKT KINASE DRUG DESIGN TERNARY COMPLEX SIGNALING PROTEIN TRANSFERASE/INHIBITOR COMPLEX
Ref.: DISCOVERY OF 2-PYRIMIDYL-5-AMIDOTHIOPHENES AS POTENT INHIBITORS FOR AKT: SYNTHESIS AND SAR STUDIES BIOORG.MED.CHEM.LETT. V. 16 4163 2006
Members (115)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 4XW5 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2UW5 ic50 = 34 nM GVN C17 H16 Cl N3 c1cc(ccc1c....
3 2JDV - L20 C24 H23 N5 O Cc1c2cc(cc....
4 2VNY - M02 C10 H14 N6 c1[nH]c2c(....
5 4IE9 - PZX C11 H11 N3 O2 Cc1cc(n[nH....
6 3FJQ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
7 2VO6 - M05 C18 H21 Cl N5 c1cc(ccc1C....
8 4UJ9 - S3N C20 H16 F3 N3 O2 c1cc(ccc1C....
9 1YDR Ki = 3 uM IQP C14 H17 N3 O2 S C[C@H]1CNC....
10 2C1A ic50 = 0.17 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
11 4UJA - 4L7 C17 H14 Br N3 O2 S c1cc2c(cc1....
12 2UW0 - GVK C22 H20 Cl N5 c1cc(ccc1c....
13 4DFX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
14 3L9L ic50 = 167 nM L9L C21 H19 F3 N4 O S c1cc(ccc1C....
15 3X2V - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
16 3MVJ ic50 = 3200 nM XFE C11 H15 N5 Cc1c[nH]c2....
17 4HPU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
18 4C35 ic50 = 0.56 uM NU3 C14 H11 N3 O2 c1cc(c2c(c....
19 4C38 ic50 = 17.4 nM VUP C11 H12 N6 O CCn1c2cc(n....
20 3ZO4 ic50 = 149 nM QWI C20 H24 N6 c1ccc(cc1)....
21 2OJF ic50 = 15 nM 4PY C22 H20 N6 O c1c(cncc1O....
22 4XW4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
23 2GNF Ki = 6 uM Y27 C14 H21 N3 O C[C@H](C1C....
24 2JDS ic50 = 27 nM L20 C24 H23 N5 O Cc1c2cc(cc....
25 3E8E - G98 C24 H29 N7 O3 CCn1c2cc(n....
26 1SVG ic50 = 2 nM I04 C27 H27 F N4 O5 COc1ccc(c(....
27 2UW3 ic50 = 80 uM GVG C10 H10 N2 Cc1c(c[nH]....
28 3L9N - L9N C19 H20 N6 S Cc1ccc(cc1....
29 2UZW Kd = 5 nM SS4 C22 H21 Br N4 O Cc1c2cc(cc....
30 3X2W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
31 2GNJ Ki = 6 uM Y27 C14 H21 N3 O C[C@H](C1C....
32 2VO0 - M03 C18 H20 Cl N5 c1cc(ccc1C....
33 1L3R - AF3 Al F3 F[Al](F)F
34 4O21 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
35 1XH5 Kd = 3400 nM R68 C33 H38 F N5 O4 CC1(CCCN[C....
36 2JDT - I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
37 2ERZ Ki = 2.2 uM HFS C14 H17 N3 O3 S c1cc2c(ccn....
38 1Q8W Kd = 5.7 uM M77 C14 H17 N3 O2 S c1cc2cnccc....
39 1STC Ki = 8 nM STU C28 H26 N4 O3 C[C@@]12[C....
40 4IAZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
41 2UVX - GVH C7 H6 N2 c1cc2cc[nH....
42 4YXR - 0RW C8 H8 N2 Cc1c2ccccc....
43 1RDQ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
44 4YXS - EMU C12 H11 N5 c1ccc(cc1)....
45 1Q8T Kd = 17.5 uM Y27 C14 H21 N3 O C[C@H](C1C....
46 4IAI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
47 2UW4 ic50 = 5.2 uM L15 C12 H15 N3 Cc1c(c[nH]....
48 2GNI Ki = 2280 nM M77 C14 H17 N3 O2 S c1cc2cnccc....
49 2UVY - GVI C13 H13 N5 CNCc1ccc(c....
50 1CDK - MYR C14 H28 O2 CCCCCCCCCC....
51 2C1B ic50 = 0.4 uM CQP C21 H22 Cl N3 O3 S c1cc2cnccc....
52 2UW8 ic50 = 77 uM GVQ C14 H14 Cl N c1ccc(cc1)....
53 3AMA Ki = 0.297 uM SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
54 2GNH Ki = 149 nM H52 C16 H21 N3 O2 S Cc1cncc2c1....
55 4IB0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
56 1SVE ic50 = 5 nM I01 C27 H26 F N3 O6 COc1ccc(c(....
57 1XH4 Kd = 34 nM R69 C28 H31 N5 O4 CN(C)c1ccc....
58 2VO7 ic50 = 15 nM M05 C18 H21 Cl N5 c1cc(ccc1C....
59 2UZU ic50 = 0.16 nM L20 C24 H23 N5 O Cc1c2cc(cc....
60 4AXA - RKD C17 H17 Cl N3 O c1cc(ccc1c....
61 2F7E ic50 = 1.3 nM 2EA C25 H22 N4 O c1ccc2c(c1....
62 1XH8 ic50 = 1700 nM R55 C33 H39 N5 O4 CC1(CCN(CC....
63 3DNE - LL1 C12 H9 N3 c1ccc2c(c1....
64 4DG0 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
65 4C34 - STU C28 H26 N4 O3 C[C@@]12[C....
66 4IAC - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
67 2UZT ic50 = 14 nM SS3 C22 H22 N4 O Cc1c2cc(cc....
68 1JBP - OCT C8 H18 CCCCCCCC
69 1ATP Kd = 60 nM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
70 3OW3 ic50 = 742 nM SMY C22 H26 N6 O S C[C@H]1c2c....
71 4IB3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
72 3ZO3 - QNI C14 H20 N6 c1[nH]c2c(....
73 4C37 ic50 = 19.7 nM Z21 C10 H9 Br N6 O CCn1c2cc(n....
74 3E8C - G96 C24 H27 N7 O3 CCn1c2cc(n....
75 1Q8U Kd = 1.1 uM H52 C16 H21 N3 O2 S Cc1cncc2c1....
76 4Z83 - 4L7 C17 H14 Br N3 O2 S c1cc2c(cc1....
77 1YDT Ki = 48 nM IQB C20 H20 Br N3 O2 S c1cc2cnccc....
78 3L9M - L9M C20 H22 N6 S Cc1ccc(cc1....
79 3AMB Ki = 0.66 uM VX6 C23 H28 N8 O S Cc1cc([nH]....
80 3DND - LL2 C10 H10 N2 S c1ccc(cc1)....
81 4IAK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
82 2UW6 ic50 = 0.28 uM GVO C17 H16 Cl N3 c1cc(ccc1c....
83 1XH7 Kd = 150 nM R96 C33 H39 N5 O4 CC1(CCCN(C....
84 3X2U - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
85 1XHA - R68 C33 H38 F N5 O4 CC1(CCCN[C....
86 4IAF - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
87 4IAD - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
88 3ZO1 ic50 = 1 uM SIJ C14 H20 N6 c1[nH]c2c(....
89 4HPT - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
90 4UJ1 - NVX C19 H16 Cl N3 O2 c1cc(cc(c1....
91 2OH0 ic50 = 18 nM 2PY C23 H21 N5 O c1cc2c(cc1....
92 4WB5 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
93 2F7X ic50 = 14 nM 4EA C23 H22 N4 O c1ccc2c(c1....
94 2UVZ - GVJ C18 H15 N5 c1ccc(cc1)....
95 3NX8 - IPH C6 H6 O c1ccc(cc1)....
96 2UW7 ic50 = 18 nM GVP C20 H20 Cl N3 c1cc(ccc1c....
97 4Z84 - NVX C19 H16 Cl N3 O2 c1cc(cc(c1....
98 1XH6 Kd = 48 nM R94 C31 H35 N5 O4 c1cc(ccc1C....
99 2VNW - M01 C11 H16 N6 c1[nH]c2c(....
100 1FMO Ki = 2.3 nM ADN C10 H13 N5 O4 c1nc(c2c(n....
101 2UZV ic50 > 3 uM SS5 C29 H34 N4 O2 Cc1c2cc(cc....
102 4UJ2 - NVV C19 H16 I N3 O2 c1cc(cc(c1....
103 4IB1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
104 2QUR - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
105 4XW6 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
106 1XH9 Kd = 17 nM R69 C28 H31 N5 O4 CN(C)c1ccc....
107 2GU8 ic50 = 0.1 nM 796 C19 H19 Cl2 N5 O S CNc1nccc(n....
108 2VO3 - M04 C19 H22 Cl N5 c1cc(ccc1C....
109 4WB8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
110 3ZO2 ic50 = 80 nM 15I C14 H20 N6 c1[nH]c2c(....
111 1SVH ic50 = 360 nM I08 C28 H28 F N3 O4 COc1ccc(c(....
112 1YDS Ki = 1.2 uM IQS C12 H15 N3 O2 S CNCCNS(=O)....
113 4IAY - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
114 4C36 ic50 = 19.8 nM ZO9 C13 H13 N5 O c1ccc2c(c1....
115 4UJB - 8BQ C19 H16 F N3 O2 c1cc(cc(c1....
70% Homology Family (116)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 4XW5 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2UW5 ic50 = 34 nM GVN C17 H16 Cl N3 c1cc(ccc1c....
3 2JDV - L20 C24 H23 N5 O Cc1c2cc(cc....
4 2VNY - M02 C10 H14 N6 c1[nH]c2c(....
5 4IE9 - PZX C11 H11 N3 O2 Cc1cc(n[nH....
6 3FJQ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
7 2VO6 - M05 C18 H21 Cl N5 c1cc(ccc1C....
8 4UJ9 - S3N C20 H16 F3 N3 O2 c1cc(ccc1C....
9 1YDR Ki = 3 uM IQP C14 H17 N3 O2 S C[C@H]1CNC....
10 2C1A ic50 = 0.17 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
11 4UJA - 4L7 C17 H14 Br N3 O2 S c1cc2c(cc1....
12 2UW0 - GVK C22 H20 Cl N5 c1cc(ccc1c....
13 4DFX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
14 3L9L ic50 = 167 nM L9L C21 H19 F3 N4 O S c1cc(ccc1C....
15 3X2V - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
16 3MVJ ic50 = 3200 nM XFE C11 H15 N5 Cc1c[nH]c2....
17 4HPU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
18 4C35 ic50 = 0.56 uM NU3 C14 H11 N3 O2 c1cc(c2c(c....
19 4C38 ic50 = 17.4 nM VUP C11 H12 N6 O CCn1c2cc(n....
20 3ZO4 ic50 = 149 nM QWI C20 H24 N6 c1ccc(cc1)....
21 2OJF ic50 = 15 nM 4PY C22 H20 N6 O c1c(cncc1O....
22 4XW4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
23 2GNF Ki = 6 uM Y27 C14 H21 N3 O C[C@H](C1C....
24 2JDS ic50 = 27 nM L20 C24 H23 N5 O Cc1c2cc(cc....
25 3E8E - G98 C24 H29 N7 O3 CCn1c2cc(n....
26 1SVG ic50 = 2 nM I04 C27 H27 F N4 O5 COc1ccc(c(....
27 2UW3 ic50 = 80 uM GVG C10 H10 N2 Cc1c(c[nH]....
28 3L9N - L9N C19 H20 N6 S Cc1ccc(cc1....
29 2UZW Kd = 5 nM SS4 C22 H21 Br N4 O Cc1c2cc(cc....
30 3X2W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
31 2GNJ Ki = 6 uM Y27 C14 H21 N3 O C[C@H](C1C....
32 2VO0 - M03 C18 H20 Cl N5 c1cc(ccc1C....
33 1L3R - AF3 Al F3 F[Al](F)F
34 4O21 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
35 1XH5 Kd = 3400 nM R68 C33 H38 F N5 O4 CC1(CCCN[C....
36 2JDT - I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
37 2ERZ Ki = 2.2 uM HFS C14 H17 N3 O3 S c1cc2c(ccn....
38 1Q8W Kd = 5.7 uM M77 C14 H17 N3 O2 S c1cc2cnccc....
39 1STC Ki = 8 nM STU C28 H26 N4 O3 C[C@@]12[C....
40 4IAZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
41 2UVX - GVH C7 H6 N2 c1cc2cc[nH....
42 4YXR - 0RW C8 H8 N2 Cc1c2ccccc....
43 1RDQ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
44 4YXS - EMU C12 H11 N5 c1ccc(cc1)....
45 1Q8T Kd = 17.5 uM Y27 C14 H21 N3 O C[C@H](C1C....
46 4IAI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
47 2UW4 ic50 = 5.2 uM L15 C12 H15 N3 Cc1c(c[nH]....
48 2GNI Ki = 2280 nM M77 C14 H17 N3 O2 S c1cc2cnccc....
49 2UVY - GVI C13 H13 N5 CNCc1ccc(c....
50 1CDK - MYR C14 H28 O2 CCCCCCCCCC....
51 2C1B ic50 = 0.4 uM CQP C21 H22 Cl N3 O3 S c1cc2cnccc....
52 2UW8 ic50 = 77 uM GVQ C14 H14 Cl N c1ccc(cc1)....
53 3AMA Ki = 0.297 uM SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
54 2GNH Ki = 149 nM H52 C16 H21 N3 O2 S Cc1cncc2c1....
55 4IB0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
56 1SVE ic50 = 5 nM I01 C27 H26 F N3 O6 COc1ccc(c(....
57 1XH4 Kd = 34 nM R69 C28 H31 N5 O4 CN(C)c1ccc....
58 2VO7 ic50 = 15 nM M05 C18 H21 Cl N5 c1cc(ccc1C....
59 2UZU ic50 = 0.16 nM L20 C24 H23 N5 O Cc1c2cc(cc....
60 4AXA - RKD C17 H17 Cl N3 O c1cc(ccc1c....
61 2F7E ic50 = 1.3 nM 2EA C25 H22 N4 O c1ccc2c(c1....
62 1XH8 ic50 = 1700 nM R55 C33 H39 N5 O4 CC1(CCN(CC....
63 3DNE - LL1 C12 H9 N3 c1ccc2c(c1....
64 4DG0 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
65 4C34 - STU C28 H26 N4 O3 C[C@@]12[C....
66 4IAC - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
67 2UZT ic50 = 14 nM SS3 C22 H22 N4 O Cc1c2cc(cc....
68 1JBP - OCT C8 H18 CCCCCCCC
69 1ATP Kd = 60 nM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
70 3OW3 ic50 = 742 nM SMY C22 H26 N6 O S C[C@H]1c2c....
71 4IB3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
72 3ZO3 - QNI C14 H20 N6 c1[nH]c2c(....
73 4C37 ic50 = 19.7 nM Z21 C10 H9 Br N6 O CCn1c2cc(n....
74 3E8C - G96 C24 H27 N7 O3 CCn1c2cc(n....
75 1Q8U Kd = 1.1 uM H52 C16 H21 N3 O2 S Cc1cncc2c1....
76 4Z83 - 4L7 C17 H14 Br N3 O2 S c1cc2c(cc1....
77 1YDT Ki = 48 nM IQB C20 H20 Br N3 O2 S c1cc2cnccc....
78 3L9M - L9M C20 H22 N6 S Cc1ccc(cc1....
79 3AMB Ki = 0.66 uM VX6 C23 H28 N8 O S Cc1cc([nH]....
80 3DND - LL2 C10 H10 N2 S c1ccc(cc1)....
81 4IAK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
82 2UW6 ic50 = 0.28 uM GVO C17 H16 Cl N3 c1cc(ccc1c....
83 1XH7 Kd = 150 nM R96 C33 H39 N5 O4 CC1(CCCN(C....
84 3X2U - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
85 1XHA - R68 C33 H38 F N5 O4 CC1(CCCN[C....
86 4IAF - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
87 4IAD - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
88 3ZO1 ic50 = 1 uM SIJ C14 H20 N6 c1[nH]c2c(....
89 4HPT - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
90 4UJ1 - NVX C19 H16 Cl N3 O2 c1cc(cc(c1....
91 2OH0 ic50 = 18 nM 2PY C23 H21 N5 O c1cc2c(cc1....
92 4WB5 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
93 2F7X ic50 = 14 nM 4EA C23 H22 N4 O c1ccc2c(c1....
94 2UVZ - GVJ C18 H15 N5 c1ccc(cc1)....
95 3NX8 - IPH C6 H6 O c1ccc(cc1)....
96 2UW7 ic50 = 18 nM GVP C20 H20 Cl N3 c1cc(ccc1c....
97 4Z84 - NVX C19 H16 Cl N3 O2 c1cc(cc(c1....
98 1XH6 Kd = 48 nM R94 C31 H35 N5 O4 c1cc(ccc1C....
99 2VNW - M01 C11 H16 N6 c1[nH]c2c(....
100 1FMO Ki = 2.3 nM ADN C10 H13 N5 O4 c1nc(c2c(n....
101 2UZV ic50 > 3 uM SS5 C29 H34 N4 O2 Cc1c2cc(cc....
102 4UJ2 - NVV C19 H16 I N3 O2 c1cc(cc(c1....
103 4IB1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
104 2QUR - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
105 4XW6 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
106 1XH9 Kd = 17 nM R69 C28 H31 N5 O4 CN(C)c1ccc....
107 2GU8 ic50 = 0.1 nM 796 C19 H19 Cl2 N5 O S CNc1nccc(n....
108 2VO3 - M04 C19 H22 Cl N5 c1cc(ccc1C....
109 4WB8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
110 3ZO2 ic50 = 80 nM 15I C14 H20 N6 c1[nH]c2c(....
111 1SVH ic50 = 360 nM I08 C28 H28 F N3 O4 COc1ccc(c(....
112 1YDS Ki = 1.2 uM IQS C12 H15 N3 O2 S CNCCNS(=O)....
113 4IAY - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
114 4C36 ic50 = 19.8 nM ZO9 C13 H13 N5 O c1ccc2c(c1....
115 4UJB - 8BQ C19 H16 F N3 O2 c1cc(cc(c1....
116 4WB7 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
50% Homology Family (116)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4XW5 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2UW5 ic50 = 34 nM GVN C17 H16 Cl N3 c1cc(ccc1c....
3 2JDV - L20 C24 H23 N5 O Cc1c2cc(cc....
4 2VNY - M02 C10 H14 N6 c1[nH]c2c(....
5 4IE9 - PZX C11 H11 N3 O2 Cc1cc(n[nH....
6 3FJQ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
7 2VO6 - M05 C18 H21 Cl N5 c1cc(ccc1C....
8 4UJ9 - S3N C20 H16 F3 N3 O2 c1cc(ccc1C....
9 1YDR Ki = 3 uM IQP C14 H17 N3 O2 S C[C@H]1CNC....
10 2C1A ic50 = 0.17 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
11 4UJA - 4L7 C17 H14 Br N3 O2 S c1cc2c(cc1....
12 2UW0 - GVK C22 H20 Cl N5 c1cc(ccc1c....
13 4DFX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
14 3L9L ic50 = 167 nM L9L C21 H19 F3 N4 O S c1cc(ccc1C....
15 3X2V - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
16 3MVJ ic50 = 3200 nM XFE C11 H15 N5 Cc1c[nH]c2....
17 4HPU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
18 4C35 ic50 = 0.56 uM NU3 C14 H11 N3 O2 c1cc(c2c(c....
19 4C38 ic50 = 17.4 nM VUP C11 H12 N6 O CCn1c2cc(n....
20 3ZO4 ic50 = 149 nM QWI C20 H24 N6 c1ccc(cc1)....
21 2OJF ic50 = 15 nM 4PY C22 H20 N6 O c1c(cncc1O....
22 4XW4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
23 2GNF Ki = 6 uM Y27 C14 H21 N3 O C[C@H](C1C....
24 2JDS ic50 = 27 nM L20 C24 H23 N5 O Cc1c2cc(cc....
25 3E8E - G98 C24 H29 N7 O3 CCn1c2cc(n....
26 1SVG ic50 = 2 nM I04 C27 H27 F N4 O5 COc1ccc(c(....
27 2UW3 ic50 = 80 uM GVG C10 H10 N2 Cc1c(c[nH]....
28 3L9N - L9N C19 H20 N6 S Cc1ccc(cc1....
29 2UZW Kd = 5 nM SS4 C22 H21 Br N4 O Cc1c2cc(cc....
30 3X2W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
31 2GNJ Ki = 6 uM Y27 C14 H21 N3 O C[C@H](C1C....
32 2VO0 - M03 C18 H20 Cl N5 c1cc(ccc1C....
33 1L3R - AF3 Al F3 F[Al](F)F
34 4O21 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
35 1XH5 Kd = 3400 nM R68 C33 H38 F N5 O4 CC1(CCCN[C....
36 2JDT - I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
37 2ERZ Ki = 2.2 uM HFS C14 H17 N3 O3 S c1cc2c(ccn....
38 1Q8W Kd = 5.7 uM M77 C14 H17 N3 O2 S c1cc2cnccc....
39 1STC Ki = 8 nM STU C28 H26 N4 O3 C[C@@]12[C....
40 4IAZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
41 2UVX - GVH C7 H6 N2 c1cc2cc[nH....
42 4YXR - 0RW C8 H8 N2 Cc1c2ccccc....
43 1RDQ - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
44 4YXS - EMU C12 H11 N5 c1ccc(cc1)....
45 1Q8T Kd = 17.5 uM Y27 C14 H21 N3 O C[C@H](C1C....
46 4IAI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
47 2UW4 ic50 = 5.2 uM L15 C12 H15 N3 Cc1c(c[nH]....
48 2GNI Ki = 2280 nM M77 C14 H17 N3 O2 S c1cc2cnccc....
49 2UVY - GVI C13 H13 N5 CNCc1ccc(c....
50 1CDK - MYR C14 H28 O2 CCCCCCCCCC....
51 2C1B ic50 = 0.4 uM CQP C21 H22 Cl N3 O3 S c1cc2cnccc....
52 2UW8 ic50 = 77 uM GVQ C14 H14 Cl N c1ccc(cc1)....
53 3AMA Ki = 0.297 uM SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
54 2GNH Ki = 149 nM H52 C16 H21 N3 O2 S Cc1cncc2c1....
55 4IB0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
56 1SVE ic50 = 5 nM I01 C27 H26 F N3 O6 COc1ccc(c(....
57 1XH4 Kd = 34 nM R69 C28 H31 N5 O4 CN(C)c1ccc....
58 2VO7 ic50 = 15 nM M05 C18 H21 Cl N5 c1cc(ccc1C....
59 2UZU ic50 = 0.16 nM L20 C24 H23 N5 O Cc1c2cc(cc....
60 4AXA - RKD C17 H17 Cl N3 O c1cc(ccc1c....
61 2F7E ic50 = 1.3 nM 2EA C25 H22 N4 O c1ccc2c(c1....
62 1XH8 ic50 = 1700 nM R55 C33 H39 N5 O4 CC1(CCN(CC....
63 3DNE - LL1 C12 H9 N3 c1ccc2c(c1....
64 4DG0 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
65 4C34 - STU C28 H26 N4 O3 C[C@@]12[C....
66 4IAC - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
67 2UZT ic50 = 14 nM SS3 C22 H22 N4 O Cc1c2cc(cc....
68 1JBP - OCT C8 H18 CCCCCCCC
69 1ATP Kd = 60 nM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
70 3OW3 ic50 = 742 nM SMY C22 H26 N6 O S C[C@H]1c2c....
71 4IB3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
72 3ZO3 - QNI C14 H20 N6 c1[nH]c2c(....
73 4C37 ic50 = 19.7 nM Z21 C10 H9 Br N6 O CCn1c2cc(n....
74 3E8C - G96 C24 H27 N7 O3 CCn1c2cc(n....
75 1Q8U Kd = 1.1 uM H52 C16 H21 N3 O2 S Cc1cncc2c1....
76 4Z83 - 4L7 C17 H14 Br N3 O2 S c1cc2c(cc1....
77 1YDT Ki = 48 nM IQB C20 H20 Br N3 O2 S c1cc2cnccc....
78 3L9M - L9M C20 H22 N6 S Cc1ccc(cc1....
79 3AMB Ki = 0.66 uM VX6 C23 H28 N8 O S Cc1cc([nH]....
80 3DND - LL2 C10 H10 N2 S c1ccc(cc1)....
81 4IAK - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
82 2UW6 ic50 = 0.28 uM GVO C17 H16 Cl N3 c1cc(ccc1c....
83 1XH7 Kd = 150 nM R96 C33 H39 N5 O4 CC1(CCCN(C....
84 3X2U - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
85 1XHA - R68 C33 H38 F N5 O4 CC1(CCCN[C....
86 4IAF - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
87 4IAD - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
88 3ZO1 ic50 = 1 uM SIJ C14 H20 N6 c1[nH]c2c(....
89 4HPT - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
90 4UJ1 - NVX C19 H16 Cl N3 O2 c1cc(cc(c1....
91 2OH0 ic50 = 18 nM 2PY C23 H21 N5 O c1cc2c(cc1....
92 4WB5 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
93 2F7X ic50 = 14 nM 4EA C23 H22 N4 O c1ccc2c(c1....
94 2UVZ - GVJ C18 H15 N5 c1ccc(cc1)....
95 3NX8 - IPH C6 H6 O c1ccc(cc1)....
96 2UW7 ic50 = 18 nM GVP C20 H20 Cl N3 c1cc(ccc1c....
97 4Z84 - NVX C19 H16 Cl N3 O2 c1cc(cc(c1....
98 1XH6 Kd = 48 nM R94 C31 H35 N5 O4 c1cc(ccc1C....
99 2VNW - M01 C11 H16 N6 c1[nH]c2c(....
100 1FMO Ki = 2.3 nM ADN C10 H13 N5 O4 c1nc(c2c(n....
101 2UZV ic50 > 3 uM SS5 C29 H34 N4 O2 Cc1c2cc(cc....
102 4UJ2 - NVV C19 H16 I N3 O2 c1cc(cc(c1....
103 4IB1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
104 2QUR - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
105 4XW6 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
106 1XH9 Kd = 17 nM R69 C28 H31 N5 O4 CN(C)c1ccc....
107 2GU8 ic50 = 0.1 nM 796 C19 H19 Cl2 N5 O S CNc1nccc(n....
108 2VO3 - M04 C19 H22 Cl N5 c1cc(ccc1C....
109 4WB8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
110 3ZO2 ic50 = 80 nM 15I C14 H20 N6 c1[nH]c2c(....
111 1SVH ic50 = 360 nM I08 C28 H28 F N3 O4 COc1ccc(c(....
112 1YDS Ki = 1.2 uM IQS C12 H15 N3 O2 S CNCCNS(=O)....
113 4IAY - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
114 4C36 ic50 = 19.8 nM ZO9 C13 H13 N5 O c1ccc2c(c1....
115 4UJB - 8BQ C19 H16 F N3 O2 c1cc(cc(c1....
116 4WB7 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2GU8; Ligand: 796; Similar sites found: 431
This union binding pocket(no: 1) in the query (biounit: 2gu8.bio1) has 101 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4WG0 CHD 0.008308 0.45966 None
2 1RZX ACE VAL LYS GLU SER LEU VAL 0.02934 0.43161 None
3 4WOP CTP 0.04392 0.40324 0.888889
4 5EQY 5RA 0.001631 0.40382 1.18694
5 4U98 ACP 0.0003055 0.51175 1.48368
6 3ICT ADP 0.04192 0.41044 1.48368
7 4NS3 NAD 0.03689 0.40144 1.48368
8 4CS9 AMP 0.02696 0.40708 1.5873
9 1HFU NAG NDG 0.002872 0.46918 1.78042
10 5CAD PCA 0.01747 0.44117 1.78042
11 4C5N ACP 0.007486 0.42013 1.81159
12 1TZD ADP 0.0001713 0.55361 1.81818
13 1W2D ADP 0.001808 0.48717 1.88679
14 1W2D 4IP 0.003156 0.42823 1.88679
15 3SHR CMP 0.03594 0.41744 2.00669
16 3A2Y TS5 0.03748 0.40386 2.03046
17 4YVN EBS 0.006094 0.47069 2.07715
18 2YW2 ATP 0.001855 0.46052 2.07715
19 4ANW O92 0.000348 0.45893 2.07715
20 3K5I ADP 0.00734 0.43225 2.07715
21 3PIJ FRU 0.04916 0.41725 2.07715
22 2ORO 228 0.04318 0.40362 2.07715
23 3SIG AR6 0.02941 0.40094 2.16606
24 1OMO NAD 0.009492 0.41558 2.17391
25 4CC6 L5Y 0.009631 0.45268 2.20126
26 1IOW PHY 0.003079 0.41634 2.28758
27 1IOW ADP 0.003079 0.41634 2.28758
28 3I0O ADP 0.0000115 0.60448 2.37389
29 2Q8E OGA 0.04094 0.42348 2.37389
30 2OS2 OGA 0.04034 0.4229 2.37389
31 2YBP 2HG 0.04482 0.42102 2.37389
32 4K37 SAM 0.03955 0.40557 2.37389
33 4WJT NAG 0.02954 0.40902 2.39521
34 3BWR GAL NGA SIA GAL BGC 0.03867 0.41934 2.57353
35 4JNJ BTN 0.03439 0.41175 2.6087
36 3TM0 ANP 0.001478 0.43381 2.6616
37 3TM0 B31 0.0018 0.42786 2.6616
38 5KJW 53C 0.001469 0.50494 2.67062
39 3OPT AKG 0.03472 0.42766 2.67062
40 5FXD H7Y 0.02107 0.41946 2.67062
41 2V58 LZJ 0.002089 0.40391 2.67062
42 1ZP9 ATP 0.0000009641 0.64483 2.71318
43 1OJZ NAD 0.03781 0.40367 2.83019
44 1XDN ATP 0.03775 0.40965 2.88809
45 5TVA COA 0.0246 0.41606 2.91667
46 2CBZ ATP 0.03486 0.42771 2.95359
47 5U9J GER 0.03373 0.42264 2.95858
48 3TII ANP 0.003014 0.4753 2.96736
49 3HQP ATP 0.04893 0.40083 2.96736
50 1OIJ AKG 0.02842 0.42723 2.99003
51 5TH5 MET 0.04488 0.41951 3.04183
52 3I9U DTU 0.03708 0.40678 3.04183
53 3KYG 5GP 5GP 0.0007417 0.4835 3.0837
54 2AQX ATP 0.001968 0.45569 3.11419
55 1GT4 UNA 0.02042 0.42015 3.14465
56 4D4U FUC GAL NAG 0.02283 0.43204 3.1746
57 4R78 AMP 0.000019 0.60059 3.23625
58 1PK8 ATP 0.0002821 0.48285 3.2641
59 1FQK ALF 0.03776 0.42678 3.38462
60 1JG3 ADN 0.01075 0.4036 3.40426
61 4ZFL 4NK 0.02723 0.4 3.4188
62 3MBI HSX 0.04209 0.41728 3.48432
63 4XYM A12 0.003173 0.45309 3.56083
64 5JDA AMP 0.03397 0.42425 3.56083
65 5KR7 6X9 0.04063 0.41454 3.56083
66 4PAB THG 0.0449 0.40274 3.56083
67 4ZYB 4SQ 0.03536 0.41438 3.73134
68 2HKA C3S 0.03425 0.40037 3.84615
69 3WVR AMP 0.0005452 0.50413 3.85757
70 2CFM AMP 0.004695 0.46501 3.85757
71 4NOS ITU 0.04732 0.41444 3.85757
72 2UYN 2KT 0.03409 0.42254 3.87597
73 4RDL FUC GAL NDG FUC 0.005404 0.47397 3.8961
74 4AVB CMP 0.04564 0.40847 3.9039
75 4OUJ LBT 0.02663 0.42113 3.90879
76 3TDV GDP 0.000001642 0.61817 3.92157
77 5C5T AKG 0.02951 0.42587 3.94737
78 1QY1 PRZ 0.0138 0.41634 4.02299
79 1Y7P RIP 0.04013 0.42192 4.03587
80 1HXD BTN 0.02902 0.40382 4.04984
81 3WUR O4B 0.04171 0.41949 4.09357
82 3ZJX BOG 0.02367 0.43675 4.15225
83 4OUC 5ID 0.0000001584 0.68493 4.1543
84 3NKS ACJ 0.005718 0.44799 4.1543
85 2Q7D ANP 0.006002 0.42165 4.1543
86 4AFK FLC 0.04906 0.40892 4.1543
87 4GCZ FMN 0.03713 0.40131 4.1543
88 4O9S 2RY 0.008479 0.41514 4.18605
89 3A3B RBF 0.03812 0.41968 4.21053
90 3NZ1 3NY 0.01801 0.43832 4.21456
91 4DSU BZI 0.01951 0.43952 4.2328
92 5C1P ADP 0.001669 0.48402 4.24837
93 5C1P DAL DAL 0.01413 0.40793 4.24837
94 1IA9 ANP 0.0001049 0.5244 4.28571
95 4FE2 ADP 0.0321 0.41661 4.31373
96 3OCP CMP 0.03367 0.41898 4.31655
97 5SVV FMN 0.01246 0.42134 4.37956
98 4ZGP ADP 0.008646 0.43897 4.43686
99 2IF8 ADP 0.000133 0.56159 4.45104
100 5LXT ACP 0.001745 0.4546 4.45104
101 4WOE ADP 0.0194 0.44194 4.45104
102 4WOE 3S5 0.03113 0.4319 4.45104
103 1FWV SGA MAG FUC 0.04962 0.41891 4.47761
104 5FUI APY 0.0002458 0.54594 4.54545
105 4DFU QUE 0.002952 0.48619 4.65839
106 3X01 AMP 0.004068 0.4788 4.74777
107 5I35 ANP 0.000003996 0.60605 5.04451
108 1GPM AMP 0.02018 0.44225 5.04451
109 3E7S AT2 0.03548 0.42452 5.04451
110 4S15 4D8 0.006926 0.43344 5.07812
111 2XG5 EC2 0.001782 0.49078 5.20231
112 2XG5 EC5 0.001782 0.49078 5.20231
113 2G30 ALA ALA PHE 0.0009897 0.50099 5.42636
114 1EPB REA 0.04313 0.40364 5.4878
115 2IO8 ADP 0.0005499 0.47371 5.63798
116 4UWH JXM 0.005536 0.45262 5.63798
117 5F6U 5VK 0.008618 0.45603 5.73248
118 4AZ3 S35 0.01578 0.41091 5.80645
119 5F2T PLM 0.02974 0.41187 5.84416
120 4USI ATP 0.01839 0.41051 5.84416
121 1PVC ILE SER GLU VAL 0.004264 0.50321 5.88235
122 5M6N 7H9 0.03511 0.42614 5.9322
123 2W5P CL8 0.001773 0.50286 6.04027
124 3DGY 2GP 0.04335 0.4193 6.18557
125 3P7N FMN 0.02561 0.4092 6.20155
126 5XG5 A2G 0.04093 0.42106 6.2069
127 3ORQ ADP 0.002097 0.458 6.23145
128 2X3J ATP 0.0265 0.40571 6.23145
129 4I9B NAD 0.03241 0.40152 6.23145
130 4RT1 C2E 0.00008092 0.54064 6.25
131 1LCK GLU GLY GLN PTR GLN PRO GLN PRO ALA 0.007781 0.44504 6.28571
132 3RGA LSB 0.04619 0.40212 6.36042
133 5E89 TD2 0.01764 0.42337 6.47482
134 4IPH 1FJ 0.02049 0.40077 6.50407
135 2PUL ACP 0.00001419 0.5785 6.52819
136 1EHI ADP 0.001973 0.46303 6.52819
137 3DNT ATP 0.003374 0.43841 6.52819
138 5JJU AMP 0.03781 0.41283 6.52819
139 4CTA ATP 0.01601 0.40552 6.52819
140 4O1P ANP 0.0000001755 0.40281 6.52819
141 5J62 FMN 0.04127 0.40176 6.52819
142 4OCV ANP 0.0001713 0.51414 6.59631
143 1TQP ATP 0.000005302 0.56394 6.73759
144 3AKK ADP 0.0001317 0.51964 6.76923
145 2YRX AMP 0.003217 0.48486 6.82493
146 4PU5 ANP 0.001415 0.45876 6.84327
147 1VL1 CIT 0.01554 0.44951 6.89655
148 3LQV ADE 0.00379 0.46932 6.95652
149 3P2H NOO 0.02146 0.41592 6.96517
150 1QKQ MAN 0.001401 0.44127 7.04225
151 5L83 ASP TRP GLU ILE VAL 0.009858 0.44364 7.14286
152 2QHS OCA 0.02062 0.43051 7.173
153 4K55 H6P 0.003722 0.4716 7.25806
154 5H4I 7HQ 0.04121 0.42435 7.30337
155 1IHU AF3 0.01302 0.41752 7.4184
156 1IHU ADP 0.01565 0.41107 7.4184
157 4LO2 GAL BGC 0.0276 0.42408 7.43243
158 4WYU SER TRP PHE GLN THR ASP LEU 0.02976 0.41186 7.54717
159 3B2Q AES 0.02804 0.41498 7.71513
160 2NZ5 226 0.02691 0.43808 8.01187
161 1W62 PYC 0.02652 0.43254 8.01187
162 2QHV OC9 0.01314 0.44526 8.09524
163 3R9V DXC 0.02381 0.43679 8.39161
164 2BVE PH5 0.03231 0.40997 8.40336
165 4JLS 3ZE 0.04707 0.42017 8.55263
166 5W2I I3P 0.0003473 0.48264 8.56031
167 5W2I ADP 0.0003473 0.48264 8.56031
168 5G0H E1Z 0.04982 0.40334 8.60534
169 4XMF HSM 0.0004536 0.5286 8.69565
170 2QX0 PH2 0.02092 0.4385 8.80503
171 3EB9 FLC 0.01538 0.41699 9.02256
172 4ZS4 ATP 0.000322 0.50095 9.12052
173 2ZL4 ALA ALA ALA ALA 0.04073 0.42192 9.18367
174 2Z6C FMN 0.004278 0.44683 9.30233
175 1YXM ADE 0.006292 0.45084 9.57096
176 5TT6 ATP 0.009547 0.4238 10.089
177 3PDT ADP 0.0006951 0.49874 10.1818
178 3TPV ADE 0.004053 0.44796 10.9792
179 1WDK N8E 0.02382 0.41367 10.9792
180 3EFS ATP 0.02255 0.42841 11.1588
181 3EFS BTN 0.03149 0.40481 11.1588
182 3VPC ADP 0.0001745 0.5045 11.3475
183 3VPB ADP 0.0001168 0.49971 11.3475
184 4WUJ FMN 0.01456 0.42112 11.5646
185 3HAV ATP 0.0002529 0.54841 11.7057
186 2J9D ADP 0.02683 0.40282 11.7647
187 2GQS ADP 0.01228 0.43131 11.8143
188 2BKK ADP 0.0001025 0.54732 11.8343
189 3Q60 ATP 0.00007865 0.54126 11.8694
190 2GC0 PAN 0.03094 0.40802 12.234
191 4O4F ATP 0.0002026 0.48918 12.5
192 4O4F IHP 0.0002612 0.48062 12.5
193 3VOT ADP 0.00125 0.49574 12.7596
194 1QPR PPC 0.03217 0.40167 13.0282
195 4OH4 ANP 0.00000001845 0.71384 14.4144
196 5DMZ ADP 0.00000007908 0.68282 14.5401
197 5LPZ ADP 0.00000004786 0.69352 14.759
198 5OCA 9QZ 0.01034 0.4632 15
199 1I1E DM2 0.0153 0.44605 15
200 3E0M SER HIS MET ALA GLU ILE 0.02081 0.43425 15
201 2QLU ADE 0.000002295 0.66115 15.2866
202 4IJP 1EH 0.00000005769 0.41567 16.0237
203 2RIO ADP 0.00000003395 0.41109 16.0237
204 4YEE 4CQ 0.04792 0.41935 17.7778
205 4GYI ADP 0.00001599 0.58945 18.1009
206 4WW7 AMP 0.0000001286 0.42053 18.3908
207 3SJK LYS PRO VAL LEU ARG THR ALA 0.002604 0.49201 18.4211
208 1X9Q FLU 0.01787 0.43791 20
209 3VHE 42Q 0.0000000149 0.64525 20.4748
210 5C03 AGS 0.00002049 0.56437 21.365
211 4YZC STU 0.000000003203 0.51142 21.365
212 4WOV 3SM 0.00001363 0.59307 22.7129
213 4Q5H ANP 0.000001513 0.6199 23.6842
214 2PZI AXX 0.00007622 0.55403 23.7389
215 2VQD AP2 0.0005069 0.48714 25
216 5NCY 8TK 0.0007238 0.452 25
217 2IVD ACJ 0.01121 0.44071 25
218 3HMO STU 0.000000375 0.6575 25.731
219 1CBK ROI 0.04408 0.42152 26.25
220 4CRL C1I 0.000001505 0.5491 26.8473
221 4JR7 GNP 0.0000000007657 0.78166 27.003
222 5GZ9 ANP 0.00000008575 0.42527 27.2131
223 2QIE 8CS 0.04931 0.40066 27.2727
224 5N87 N66 0.000000001838 0.65222 27.7955
225 1Q8Y ADP 0.00000001637 0.43024 27.8932
226 4BTK DTQ 0.00000009353 0.40592 27.8932
227 3UIM ANP 0.0000001223 0.67353 27.9141
228 5KO1 6UY 0.000002375 0.61736 27.9152
229 5UIU 8CG 0.0000000234 0.4673 28.1734
230 4IDT T28 0.000000002449 0.76691 28.1899
231 3VRY B43 0.000000396 0.60838 28.1899
232 1U5R ATP 0.002871 0.40883 28.4866
233 3PP0 03Q 0.0000000211 0.65772 28.7834
234 4E93 GUI 0.00000005601 0.61062 28.7834
235 3C1X CKK 0.0001626 0.50593 28.7834
236 5MY8 RXZ 0.000002012 0.40393 28.7834
237 3LXN MI1 0.0000000002958 0.7816 28.9308
238 3KMW ATP 0.000228 0.51812 29.1513
239 1VJY 460 0.000000000323 0.70015 29.3729
240 5T8O 76Z 0.0000000009652 0.75734 29.3769
241 5BVE 4VG 0.0000000000268 0.60139 29.3769
242 4H3P ANP 0.00000001745 0.71502 29.6736
243 4XH0 ADP 0.00001953 0.61215 29.6736
244 4H3Q ANP 0.00000002675 0.43876 29.6736
245 3H9R TAK 0.00000361 0.64 29.697
246 4AZT LY2 0.0001806 0.54061 30
247 4A4Z ANP 0.02252 0.42844 30
248 5IQD RIO 0.00001346 0.42278 30
249 5IQD GNP 0.00001091 0.42278 30
250 4XTR ADP 0.0247 0.40996 30
251 5HCY 60D 0.00000000769 0.59453 30.2115
252 4QTB 38Z 0.000000001058 0.49702 30.2671
253 5EOB 5QQ 0.0000006465 0.49394 30.4075
254 4GJ3 0XP 0.0000000002772 0.70959 30.4636
255 3E8N ATP 0.0000005259 0.52727 30.5638
256 3E8N VRA 0.0000005259 0.52727 30.5638
257 3OFM 4B0 0.000000001326 0.40658 30.5714
258 2PVN P63 0.0000000006647 0.70794 30.6818
259 4NFN 2KC 0.0000001983 0.67136 30.7443
260 4UX9 ANP 0.0000000009265 0.75818 30.8605
261 2H8H H8H 0.000000004573 0.74357 30.8605
262 1Y57 MPZ 0.00000001234 0.68923 30.8605
263 3GNI ATP 0.00000009528 0.66314 30.8605
264 3ALN ANP 0.0000001819 0.64987 30.8869
265 4KBA 1QM 0.0000006697 0.58734 31.1178
266 5W4W 9WG 0.0000004753 0.57828 31.1178
267 2B9J ADP 0.00000001347 0.72984 31.1573
268 2B9I ADP 0.000000009004 0.72913 31.1573
269 3PE2 E1B 0.0000002884 0.48486 31.1573
270 2B9H ADP 0.000000005723 0.43047 31.1573
271 4CLI 5P8 0.0000006868 0.47043 31.1927
272 4E1Z 0MX 0.000000001469 0.73133 31.2715
273 5JGA 6KC 0.000000003209 0.66027 31.4286
274 3LXK MI1 0.000000001206 0.70418 31.4985
275 3KRR DQX 0.0000000006206 0.59846 31.5254
276 3NW7 LGV 0.00002321 0.43275 31.5961
277 2WU6 DKI 0.000000009256 0.69492 31.7507
278 2B9F ADP 0.00000001951 0.41368 31.7507
279 5LXC 7AA 0.000000001184 0.41301 31.7507
280 4U44 3D9 0.00000003701 0.40919 31.9277
281 5X8I SQZ 0.0000000005377 0.78919 32.0475
282 5HVJ ANP 0.0000006423 0.69493 32.0635
283 3KRL KRL 0.0000003216 0.63131 32.2388
284 1OPK P16 0.0000002453 0.58995 32.3442
285 4P5Z Q7M 0.0000005915 0.54798 32.3442
286 2OO8 RAJ 0.00002245 0.5458 32.4921
287 4NST ADP 0.00000005906 0.68904 32.6409
288 4NST AF3 0.000003052 0.60961 32.6409
289 4F9C 0SX 0.00000000764 0.41177 32.6409
290 1CM8 ANP 0.00000002543 0.40917 32.6409
291 1K3A ACP 0.000003026 0.6272 32.7759
292 3ORK AGS 0.000002902 0.57032 32.7974
293 4Y85 499 0.000006503 0.59546 32.8313
294 4Y8D 49J 0.000000007196 0.7339 32.9377
295 4IZY 1J2 0.0000002353 0.64459 32.9377
296 5TO8 7FM 0.000002675 0.51997 32.9787
297 4AT3 LTI 0.000003822 0.54591 33.1104
298 5BYZ 4WE 0.000000007572 0.65127 33.2344
299 1OUK 084 0.000003955 0.50412 33.2344
300 4Y93 746 0.0000009897 0.59088 33.8279
301 5EFQ ADP 0.00000006489 0.40561 34.1246
302 3PLS ANP 0.0000003941 0.65643 34.2282
303 5AX9 4KT 0.00000001078 0.72529 34.4156
304 3TTI KBI 0.000000003518 0.68438 34.4214
305 4FL3 ANP 0.00000003398 0.67658 34.4214
306 4WHZ 3NL 0.0000002929 0.5255 34.4214
307 4QMN DB8 0.0000000008687 0.66466 34.5161
308 4AU8 Z3R 0.0000000328 0.74035 34.7973
309 4AUA 4AU 0.0000009933 0.63632 34.8534
310 4OAV ACP 0.0000001846 0.67292 35
311 1I7L ATP 0.0002718 0.48741 35
312 3W0O ADP 0.0004993 0.45865 35
313 3W0O HY0 0.0004993 0.45865 35
314 2Y69 CHD 0.02955 0.43175 35
315 5TVF PUT 0.04289 0.42567 35
316 5TVF CGQ 0.02767 0.42003 35
317 4ASE AV9 0.00000008862 0.62473 35.1275
318 4M69 ANP 0.000005435 0.58019 35.1438
319 2HK5 1BM 0.000000001472 0.44854 35.1852
320 4YZN 4K5 0.0000000001816 0.77269 35.1916
321 4EWH T77 0.0000000005439 0.7189 35.2727
322 5NKB 8ZT 0.0000001066 0.56288 35.2941
323 5AWM ANP 0.0000002054 0.69781 35.3116
324 5JFS 6K0 0.000003461 0.4396 35.3896
325 2XVD AS6 0.00000001896 0.64698 35.4305
326 3DAK ANP 0.000000636 0.65406 35.5172
327 4YMJ 4EJ 0.0000003128 0.71586 35.5263
328 2BPM 529 0.000000003159 0.59035 35.5987
329 3E7O 35F 0.0000005175 0.572 35.6083
330 1UNH IXM 0.00000006286 0.71506 35.6164
331 4XV1 904 0.00000002027 0.47886 35.6164
332 3O0G 3O0 0.00000001047 0.41453 35.6164
333 5MJA 7O3 0.000000002661 0.41244 35.7377
334 5HES 032 0.00000001368 0.43265 35.8306
335 2JLD AG1 0.000000003488 0.6529 35.905
336 4NM5 ADP 0.0000001271 0.6431 35.905
337 5H2U 1N1 0.0000002164 0.66136 35.9551
338 3F7Z 34O 0.00000004551 0.40912 36.2018
339 3GGF GVD 0.0000000006186 0.80803 36.2126
340 4X7Q 3YR 0.0000000003918 0.79594 36.2179
341 5DA3 58V 0.0000005988 0.67299 36.2264
342 5HX8 66P 0.0000000007596 0.72019 36.4238
343 5M06 ADP 0.00001109 0.59061 36.5942
344 2A19 ANP 0.0000004373 0.68028 36.6197
345 4CFU 2WC 0.000000004833 0.76239 36.6337
346 4G31 0WH 0.00000261 0.53969 36.7893
347 1JPA ANP 0.000001894 0.67484 36.859
348 4BCM T7Z 0.0000004858 0.69803 36.8771
349 2XMY CDK 0.0000001475 0.52516 36.9128
350 4EUU BX7 0.000000006064 0.68115 36.9906
351 4BCN T9N 0.000000007223 0.76413 37
352 4CQE CQE 0.00000009263 0.65638 37.0504
353 3TKI S25 0.000000003247 0.56012 37.1517
354 2HY0 306 0.00000003815 0.72639 37.2671
355 4AG8 AXI 0.0000001508 0.57899 37.3418
356 2F57 23D 0.00000008922 0.69767 37.3887
357 4ITH RCM 0.006484 0.43163 37.415
358 3SLS ANP 0.0000003081 0.63218 37.5
359 3SLS 77D 0.001464 0.47336 37.5
360 5U6C 7YS 0.0000002541 0.63605 38.0952
361 2Y6O 1N1 0.00000001242 0.69684 38.1443
362 4K33 ACP 0.0000000331 0.4192 38.1538
363 4JDI ANP 0.0000001097 0.4107 38.2789
364 2PVF ACP 0.000000006461 0.74581 38.3234
365 4RFM 3P6 0.0001176 0.43966 38.3459
366 5JKG 6LF 0.0000005009 0.4573 38.5852
367 4BHN BH9 0.000000002043 0.74196 38.6228
368 2OFV 242 0.0000002446 0.57096 38.6282
369 1V0O INR 0.000000009717 0.71853 38.8889
370 5DH3 5BS 0.0000001801 0.65008 39.0476
371 5HQ0 LZ9 0.0000000005286 0.76969 39.0728
372 3GQI ACP 0.00000000359 0.74872 39.2638
373 1U59 STU 0.0000000006472 0.78524 39.3728
374 3EKK GS2 0.0000001048 0.58041 39.4137
375 3IGO ANP 0.00000003986 0.67336 39.4659
376 5TA6 79D 0.000002439 0.56345 39.4659
377 5VC5 96M 0.0000000166 0.46449 39.7924
378 3BU5 ATP 0.000000005422 0.42952 39.8693
379 4XLI 1N1 0.000000001122 0.78387 39.9254
380 1GMN IDS SGN IDS SGN IDS 0.01483 0.44588 40
381 4YLL 4E3 0.00000001373 0.44445 40
382 5LUN OGA 0.02307 0.42788 40
383 3KN5 ANP 0.000000007689 0.41243 40
384 4BFM ANP 0.000000003481 0.73102 40.1198
385 3CY2 MB9 0.00000000381 0.71248 40.1274
386 5USZ SKE 0.0000002135 0.60848 40.1384
387 3SXS PP2 0.000000004152 0.72741 40.2985
388 4N70 2HX 0.000000007653 0.53627 40.5488
389 3RI1 3RH 0.00000001452 0.46198 40.5751
390 2WQN ADP 0.000008371 0.60412 40.6452
391 4CSV STI 0.000002809 0.58186 40.7273
392 3G5D 1N1 0.000000000677 0.58711 40.9091
393 4U0I 0LI 0.000000491 0.57771 40.9524
394 2X2M X2M 0.0000000001019 0.47548 41.0828
395 5VCV 1N1 0.000000004162 0.70293 41.1576
396 5UR1 YY9 0.0000009612 0.46497 41.1576
397 4TWP AXI 0.0000000766 0.55594 41.3284
398 3FHR P4O 0.00000003991 0.689 41.369
399 2YAB AMP 0.0000000001742 0.80259 41.8398
400 3SRV S19 0.0000000009443 0.4262 41.8773
401 5FBN 5WF 0.000000263 0.45903 42.0664
402 3SXF BK5 0.0000004481 0.5653 42.1365
403 4F4P 0SB 0.0000001215 0.52193 42.4908
404 4I6H 1C8 0.000003277 0.60344 42.5325
405 3GC0 AMP 0.00002615 0.57829 42.5532
406 3C0G 3AM 0.000000002139 0.79173 42.73
407 3HZT J60 0.000002348 0.64131 42.73
408 1BYG STU 0.00000000622 0.75679 42.8058
409 5DEY 59T 0.00000004831 0.53709 43.0976
410 3BZ3 YAM 0.000005296 0.46799 43.1159
411 2X4Z X4Z 0.000000001068 0.66711 43.5811
412 5IH9 6BF 0.000000003888 0.5036 43.5821
413 3GC8 B45 0.00000003578 0.67554 43.6202
414 3M2W L8I 0.000000001418 0.40986 44.1472
415 5DRB 5FJ 0.00001946 0.47076 44.3299
416 2VZ6 FEF 0.00000001555 0.74674 44.7284
417 4KS7 X4Z 0.0000000202 0.67948 44.863
418 3NEM ATP 0.04437 0.41246 45
419 4A4X JUP 0.0000003502 0.60493 46.2366
420 2WEI VGG 0.0000008119 0.64865 46.3415
421 5A6N U7E 0.00000005264 0.4236 46.6431
422 4WNP 3RJ 0.0000000008185 0.81351 47.0383
423 4USF 6UI 0.000001759 0.40177 47.0395
424 2YAK OSV 0.0000000000633 0.74305 47.3684
425 5UOX 8GY 0.0000000008996 0.74972 47.6015
426 4L9I 8PR 0.000000007306 0.74314 47.7745
427 4FG8 ATP 0.00000001397 0.43728 47.9365
428 2ZV2 609 0.000000002154 0.80349 47.9866
429 1PHK ATP 0.00000000001655 0.47026 48.3221
430 5JZJ AN2 0.000000001836 0.77317 48.8215
431 2XK9 XK9 0.0009377 0.41261 49.0683
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