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Receptor
PDB id Resolution Class Description Source Keywords
4DCT 2.3 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF B. SUBTILIS ENGA IN COMPLEX WITH HALF-O GDP BACILLUS SUBTILIS GTPASE ENGA GDP PROTEIN BINDING HYDROLASE
Ref.: POTASSIUM ACTS AS A GTPASE-ACTIVATING ELEMENT ON EA NUCLEOTIDE-BINDING DOMAIN OF THE ESSENTIAL BACILLUS ENGA. PLOS ONE V. 7 46795 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:501;
A:502;
Valid;
Valid;
none;
none;
Kd = 8 uM
443.201 C10 H15 N5 O11 P2 c1nc2...
SO4 A:503;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4DCT 2.3 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF B. SUBTILIS ENGA IN COMPLEX WITH HALF-O GDP BACILLUS SUBTILIS GTPASE ENGA GDP PROTEIN BINDING HYDROLASE
Ref.: POTASSIUM ACTS AS A GTPASE-ACTIVATING ELEMENT ON EA NUCLEOTIDE-BINDING DOMAIN OF THE ESSENTIAL BACILLUS ENGA. PLOS ONE V. 7 46795 2012
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 2HJG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4DCT Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4DCS Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4DCU Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 2HJG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4DCT Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4DCS Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4DCU Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 2HJG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4DCT Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4DCS Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4DCU Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1MKY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4DCT; Ligand: GDP; Similar sites found with APoc: 670
This union binding pocket(no: 1) in the query (biounit: 4dct.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2A2C ADP 0.877193
2 2A2C NG1 0.877193
3 3FKQ ATP 1.34048
4 5I34 GDP 1.36054
5 2VVG ADP 1.42857
6 4LIK CIT 1.53061
7 2WHX ADP 1.53509
8 2JLR ANP 1.55211
9 1SQ5 ADP 1.62338
10 1QF5 GDP 1.62413
11 1QF5 RPL 1.62413
12 3BFX A3P 1.68919
13 3P4X ADP 1.69492
14 3ZFD ANP 1.7094
15 1NHX FTB 1.75439
16 2GMV UN8 1.75439
17 1NHX PEP 1.75439
18 2GMV PEP 1.75439
19 1OS1 ATP 1.75439
20 1OS1 PYR 1.75439
21 1OYY AGS 1.75439
22 2ZFI ADP 1.91257
23 4KBF AMP 1.91781
24 5I0H ADP BEF 1.97368
25 3B7G ANP 2.17391
26 2Q2Y MKR 2.17984
27 2Q2Y ADP 2.17984
28 2BIF SIN 2.19298
29 2BIF ANP 2.19298
30 4IOK XPO 2.19298
31 4IOK ADP 2.19298
32 5LTJ ADP 2.19298
33 5XDR ADP 2.19298
34 4YJ1 ADP 2.19298
35 5LTJ BEF 2.19298
36 3RC3 ANP 2.19298
37 4YNU FAD 2.19298
38 1QHG ATP 2.19298
39 1JQN DCO 2.19298
40 5UIV ADP 2.20264
41 5LB3 ADP 2.24719
42 3EZ2 ADP 2.26131
43 1P9B GDP 2.26244
44 1JS8 MAN MAN BMA 2.28426
45 4AG5 ADP 2.29592
46 5WC2 ADP 2.31481
47 5VGR GDP 2.32019
48 2XT3 ADP 2.32558
49 1SVM ATP 2.38727
50 1J99 AND 2.38908
51 2GKS ADP 2.41228
52 5IRN ADP 2.41228
53 2FAH GDP 2.41228
54 1YTM ATP 2.41228
55 3E1T FAD 2.41228
56 3E70 GDP 2.43902
57 1NJR XYL 2.46479
58 1ION ADP 2.46914
59 2XZ9 PYR 2.46914
60 3FYH ADP 2.48447
61 1HTW ADP 2.53165
62 3FWY ADP 2.54777
63 5K5Z ANP 2.54777
64 5AK0 8V1 2.63158
65 1TQ4 GDP 2.66344
66 1G41 ADP 2.7027
67 1NST A3P 2.76923
68 4OHY ANP 2.78422
69 1FNN ADP 2.82776
70 1OXV ANP 2.83286
71 1YQT ADP 2.85088
72 1T5C ADP 2.86533
73 2AWN ADP 2.88714
74 3QXC ATP 2.89256
75 3DC4 ADP 2.90698
76 5L3W GDP 2.94118
77 2PL3 ADP 2.9661
78 2GDJ ANP 3.0303
79 1CR1 TTP 3.04054
80 3QVV A3P 3.05085
81 3QVV 3QV 3.05085
82 4IDN GNP 3.07018
83 3TBK ANP 3.07018
84 3Q9L ATP 3.07692
85 2FNA ADP 3.08123
86 5MVR ADP 3.08642
87 2WOJ ADP ALF 3.10734
88 3ZS9 ADP ALF 3.10734
89 1FP6 ADP 3.11419
90 1F9V ADP 3.17003
91 6A20 ADP 3.20366
92 3COB ADP 3.25203
93 4WZA ACP 3.26087
94 4WZA ADP 3.26087
95 5VHC BEF ADP 3.28947
96 1P72 ADP 3.29341
97 1ZCB GDP 3.31492
98 6DEF GCP 3.32481
99 3ZQ6 ADP ALF 3.39506
100 3EWA ANP 3.41615
101 5MEX PAP 3.41615
102 5MEX SZZ 3.41615
103 1OE0 TTP 3.47826
104 1LVK MNT BEF 3.50877
105 4GOX A3P 3.51438
106 4H1V GNP 3.52304
107 2ZE7 AMP 3.55731
108 2ZE7 DST 3.55731
109 2Y65 ADP 3.56164
110 5JCP GDP ALF 3.57995
111 3FVQ ATP 3.62117
112 1IWE IMP 3.72807
113 1F5N GNP 3.72807
114 2ZPT A3P 3.72881
115 5ZBR ANP 3.73333
116 1G3M PCQ 3.7415
117 1G3M A3P 3.7415
118 4XGU ADP 3.77358
119 2NCD ADP 3.80952
120 2J5V PCA 3.81471
121 1U1I NAD 3.82653
122 5BYK OAQ 3.861
123 5BYK A3P 3.861
124 4E03 ADP 3.8835
125 2OG2 MLI 3.89972
126 3AB4 THR 3.93258
127 2CE7 ADP 3.94737
128 4BFW ZVW 3.94737
129 4YDS ATP 3.94737
130 4TL6 ANP 3.95257
131 4WEI GLC GAL 3.97112
132 2ZTS ADP 3.98406
133 1AQU A3P 4.0404
134 3BFV ADP 4.05904
135 4LJ9 ACP 4.12979
136 3T34 GDP 4.16667
137 1K6M AGS 4.16667
138 6C90 ADP 4.16667
139 2ZPA ADP 4.16667
140 1BO4 COA 4.16667
141 2IYL GDP 4.22535
142 6CS8 F9Y 4.29043
143 4UXH T5A 4.34783
144 1R6B ADP 4.38596
145 4ZDJ UTP 4.38596
146 2ZJ5 ADP 4.38596
147 4IEE AGS 4.38596
148 2JAQ DCP 4.39024
149 5G3Y ADP 4.42478
150 2CHG ANP 4.42478
151 5G41 AP5 4.4843
152 3DKP ADP 4.4898
153 4FCW ADP 4.50161
154 4U00 ADP 4.5082
155 3B5J 12D 4.52675
156 4HSE ADP 4.53401
157 1OFH ADP 4.5977
158 5TSH ADP 4.60526
159 5TSH ANP 4.60526
160 3HU3 AGS 4.60526
161 4R43 GDP 4.60526
162 5IFS ADP 4.60526
163 1ZIN AP5 4.60829
164 3A4M ADP 4.61538
165 5M7P ADP 4.62555
166 1A2C 34H LEU PRJ OAR 4.6332
167 1V8K ANP 4.63415
168 3B9Q MLI 4.63576
169 3REF GDP 4.63918
170 1G6H ADP 4.66926
171 4TMK T5A 4.69484
172 4RZ3 ADP 4.74576
173 2C9O ADP 4.82456
174 2D7D ADP 4.82456
175 1JJV ATP 4.85437
176 2X7I CIT 4.87013
177 5HCN GCP 4.98084
178 5EXT ADP 5
179 1Q20 A3P 5.01672
180 1Q20 PLO 5.01672
181 5HR5 ADP 5.04386
182 4A4Z ANP 5.04386
183 1S3G AP5 5.06912
184 5FHD ADP ALF 5.08083
185 5FTB ANP 5.08083
186 2XTZ GSP 5.08475
187 5U32 GDP 5.08475
188 1W5T ANP 5.09709
189 1W5T ADP 5.09709
190 1L2T ATP 5.10638
191 3KJI ADP 5.11811
192 2B8W ALF 5GP 5.18293
193 1BG2 ADP 5.23077
194 3VX3 ADP 5.24194
195 1X6V ADP 5.26316
196 2OFW ADX 5.28846
197 2HF9 GSP 5.30973
198 1CS4 GSP 5.33333
199 4WOP CTP 5.33333
200 2BCG GDP 5.33981
201 1DAK DPU 5.35714
202 1DAK ADP 5.35714
203 3TLJ SAH 5.36193
204 3CPJ GDP 5.38117
205 1JJ7 ADP 5.38462
206 1IN4 ADP 5.38922
207 1UKZ ADP 5.41872
208 2QEN ADP 5.42857
209 2W58 ADP 5.44554
210 2O0J ADP 5.45455
211 1IHU ADP 5.48246
212 1IHU AF3 5.48246
213 1GXU 2HP 5.49451
214 2EFE GNH 5.52486
215 4NU0 AP5 5.52995
216 4DKX GDP 5.55556
217 5GVR LMR 5.55556
218 5ZB0 ADP 5.55556
219 5ZB0 TYD 5.55556
220 6AU6 GDP 5.57029
221 1NN5 ANP 5.5814
222 1NN5 2DT 5.5814
223 4TTQ ATP 5.5814
224 6AIC AMP 5.60748
225 1Z83 AP5 5.61225
226 6B8B ADP 5.62249
227 4ZJS 4P0 5.65217
228 4NE2 SH2 5.68862
229 4NE2 ADP 5.68862
230 1XKV ATP 5.70175
231 2IS6 ADP 5.70175
232 2XAU ADP 5.70175
233 2Z5F A3P 5.7047
234 1I0B PEL 5.72289
235 6B4K ANP 5.81395
236 1Z08 GNP 5.88235
237 5K04 COA 5.88235
238 2FSH ANP 5.92105
239 1NY5 ADP 5.94315
240 3DZD ADP 5.97826
241 5BN3 ADP 6.00962
242 4QOS ADP 6.03774
243 2QZ4 ADP 6.10687
244 2GK6 ADP 6.14035
245 5Y6N ADP 6.16438
246 3QKT ANP 6.19469
247 3BOS CDP 6.19835
248 1S8F GDP 6.21469
249 1Z6T ADP 6.26058
250 2RGX AP5 6.31068
251 3IO3 ADP 6.32184
252 2WKQ GTP 6.3253
253 5CK5 GDP 6.32911
254 1XPJ TLA 6.34921
255 1G6O ADP 6.36364
256 2GWH A3P 6.37584
257 1XEX ATP 6.39535
258 4QM7 GTP 6.43275
259 5Z69 AGS 6.45161
260 1GOJ ADP 6.47887
261 5W76 GDP 6.49351
262 4GBM A3P 6.50155
263 1M7B GTP 6.52174
264 1Y63 ADP 6.52174
265 2F9L GDP 6.53266
266 2QG6 NMN 6.53266
267 5WRI A3P 6.5625
268 3T1O GDP 6.56566
269 3V2U ATP 6.621
270 5TED SKM 6.63717
271 3BC1 GNP 6.66667
272 4J0Q GDP 6.69746
273 5W7Q GDP 6.70241
274 2Y8E GNP 6.70391
275 2B8T THM 6.72646
276 3VPD BUA 6.76157
277 4ZG4 VO4 ADP 6.79825
278 4IHQ ADP 6.79825
279 1OIV GDP 6.80628
280 1OIX GDP 6.80628
281 4YMU ATP 6.81818
282 5KSZ GCP 6.83962
283 5SZH GNP 6.89655
284 1RYH GNP 6.89655
285 2BME GNP 6.98925
286 3EC1 GDP 7.04607
287 4M9Q GNP 7.04846
288 1YZQ GNP 7.05882
289 1G16 GDP 7.05882
290 1JI0 ATP 7.08333
291 5OEC GDP 7.10383
292 1U0J ADP 7.11611
293 3QBT GNP 7.14286
294 1ZUI SKM 7.14286
295 4RD0 GDP 7.22892
296 3FIU POP 7.22892
297 4PFO ADP 7.23684
298 6FAA ADP 7.23684
299 4WZ6 ATP 7.24138
300 1VG8 GNP 7.24638
301 1VG0 GDP 7.24638
302 1B0U ATP 7.25191
303 1Z0F GDP 7.26257
304 1E96 GTP 7.29167
305 1I4D GDP 7.29167
306 5H68 AGS 7.35294
307 2OZE AGS 7.38255
308 4BQS ADP 7.38636
309 4BQS K2Q 7.38636
310 2C78 GNP 7.40741
311 2C77 GNP 7.40741
312 4JLV ADP 7.43494
313 4LPS GDP 7.43802
314 5JCZ GDP 7.45614
315 5H7J GCP 7.45614
316 4LX0 BEF GDP 7.49415
317 3KTA AP5 7.51445
318 1MH1 GNP 7.52688
319 4PX9 ADP 7.53425
320 2HV8 GTP 7.55814
321 1Z0K GTP 7.55814
322 1G4U GDP 7.6087
323 4ZNL BEF ADP 7.66423
324 5W75 GDP 7.67544
325 4ZKD GDP 7.67544
326 1VKJ A3P 7.7193
327 1OW3 GDP 7.77202
328 5O74 GDP 7.77778
329 2D7C GTP 7.78443
330 1VHT BA3 7.79817
331 5GOE GDP 7.81991
332 2FJU GSP 7.86517
333 3TMK T5A 7.87037
334 5YV5 ADP 7.89474
335 5KUT GDP 7.93651
336 3ITJ CIT 7.98817
337 2CBZ ATP 8.01688
338 4LHW GNP 8.04598
339 1KK1 GNP 8.04878
340 1M7G ADX 8.05687
341 1M7G AV2 8.05687
342 1M7G ADP 8.05687
343 5IRC GDP 8.06452
344 1LVG ADP 8.08081
345 1VG1 GDP 8.10811
346 1VG9 GDP 8.10811
347 6BCB GSP 8.10811
348 4D0N GDP 8.10811
349 6BCA GSP 8.10811
350 5HPY GDP 8.10811
351 3LXR GDP 8.10811
352 6BC0 GSP 8.10811
353 1KMQ GNP 8.15217
354 4V03 ADP 8.17121
355 3ZIA ATP 8.19672
356 3ZIA ADP 8.19672
357 3RAB GNP 8.28402
358 2PZE ATP 8.29694
359 5TIV A3P 8.3004
360 3H86 AP5 8.33333
361 1KAO GDP 8.38323
362 1L5Y BEF 8.3871
363 2D2F ADP 8.4
364 3MD0 GDP 8.4507
365 1W0J ADP 8.45588
366 1W0J ADP BEF 8.45588
367 1TX4 ALF GDP 8.47458
368 3UIE ANP 8.5
369 5LLB 6YZ 8.55019
370 1DAR GDP 8.55263
371 5H7K GDP 8.56423
372 1AKY AP5 8.63636
373 2F3R G5P 8.69565
374 1QF9 ALF 8.76289
375 1QF9 C5P 8.76289
376 1QF9 ADP 8.76289
377 4YS0 ADP 8.77193
378 1NJF ADP 8.8
379 1NJF AGS 8.8
380 3T12 GDP ALF 8.82353
381 3U6B GDP 8.88325
382 5JBQ GDP 8.88325
383 4P3Y GDP 8.88325
384 4G5G GDP 8.88325
385 3U6K GDP 8.88325
386 4PC3 GDP 8.88325
387 4CVN ADP 8.90052
388 1D8T GDP 8.90585
389 2BVN GNP 8.90585
390 1Z2A GDP 8.92857
391 3RLF ANP 8.94737
392 3E5H GNP 8.98876
393 1D2E GDP 9.06801
394 3TK1 GDP 9.09091
395 5E5U MLI 9.09091
396 3MGB PAP 9.09091
397 4XSH GSP 9.13242
398 3NKV GNP 9.14286
399 1Z0A GDP 9.1954
400 3BD9 A3P 9.28571
401 1Z0N BCD 9.375
402 3WXM GTP 9.42982
403 1R0X ATP 9.44056
404 3IIJ ADP 9.44444
405 4KVA GTP 9.46602
406 4LC1 GDP 9.49555
407 2PEZ DAT 9.49721
408 2PEZ GGZ 9.49721
409 1UJ2 ADP 9.52381
410 1UJ2 C5P 9.52381
411 2DPY ADP 9.58904
412 3VMF GTP 9.65147
413 1YZN GNP 9.72973
414 5J1S ATP 9.7561
415 2RCN GDP 9.77654
416 1SKQ GDP 9.88506
417 1SVK ALF GDP 9.91501
418 1GP2 GDP 9.91501
419 2ZR9 DTP 10.0287
420 2VB6 ADP BEF 10.0671
421 3IUY AMP 10.0877
422 2G77 GDP 10.101
423 4PPF FLC 10.2857
424 2QQ0 ANP 10.3261
425 2QQ0 THM 10.3261
426 2QQ0 ADP 10.3261
427 2QQ0 TMP 10.3261
428 5IRR GSP 10.3896
429 1DS6 GDP 10.4167
430 2HCJ GDP 10.4478
431 1CXZ GSP 10.4651
432 1G3Q ADP 10.5485
433 1Y3A GDP 10.6383
434 3FB4 AP5 10.6481
435 4XOI GTP 10.7407
436 2OM2 GDP 10.7692
437 3LRE ADP 10.9859
438 4XTR ATP 11.0599
439 4XTR ADP 11.0599
440 4XVU ATP 11.0599
441 2IXE ATP 11.0701
442 4Q1A UDP 11.0714
443 4Q1A 2XZ 11.0714
444 1BH2 GSP 11.1111
445 2ORV 4TA 11.1111
446 4C4P GNP 11.215
447 2FH5 GTP 11.215
448 3Q72 GNP 11.4458
449 3TNF GNP 11.4583
450 1H65 GDP 11.4815
451 3SBD GNP 11.7647
452 4KFU ACP 11.7925
453 4LYA ATP 11.8421
454 1HE1 GDP 11.8519
455 2YOH WMJ 11.9048
456 1A4R GDP 12.0419
457 1A4R GNH 12.0419
458 2NGR GDP 12.0419
459 1GRN GDP 12.0419
460 4ITR GDP 12.0419
461 1XX6 ADP 12.0419
462 3BER AMP 12.0482
463 1B7T ADP 12.1795
464 3SFV GDP 12.2093
465 1KK8 BEF ADP 12.3377
466 2GJ5 VD3 12.3457
467 2XTN GTP 12.3932
468 1PUJ GNP 12.4113
469 5XKT GNP 12.5
470 5MZN ADP 12.5
471 1T8U UAP SGN IDS SGN 12.5
472 1T8U A3P 12.5
473 4YC7 GNP 12.7072
474 2VBQ BSJ 12.7273
475 1NF3 GNP 12.8205
476 1D2N ANP 12.8676
477 1FQK GDP 12.9231
478 1FQJ GDP 12.9231
479 1FQJ ALF 12.9231
480 1FQK ALF 12.9231
481 3CNL GNP 12.9771
482 3DOE GTP 13.0208
483 5L3V GDP 13.0435
484 4OI4 ATP 13.0435
485 5L3S GNP 13.0872
486 5L3S G 13.0872
487 1WDT GTP 13.1579
488 4R2I ANP 13.3333
489 1G7S GDP 13.3772
490 1KSH GDP 13.4409
491 5FG3 GDP 13.5965
492 4NCN GTP 13.5965
493 2WMO GTP 13.6842
494 1GOT GDP 13.6986
495 4D81 ADP 13.7809
496 1E2K TMC 13.8973
497 5M04 GDP 14.0351
498 5N69 ADP 14.0704
499 1F2U ATP 14.094
500 1TAD GDP 14.1975
501 1TAD ALF 14.1975
502 2EW1 GNP 14.4279
503 1RRC ADP 14.6179
504 5J1J ANP 14.7368
505 6H5E ANP 14.741
506 1UAD GNP 14.8571
507 5KSP GDP 15.2632
508 5BXQ GDP 15.2778
509 4HAT GNP 15.2778
510 3CH5 GDP 15.2778
511 1IBR GNP 15.2778
512 1ZC3 GNP 15.4286
513 1U8Z GDP 15.4762
514 3M1I GTP 15.5251
515 3WYF GTP 15.5251
516 1RJ9 GCP 15.6667
517 3TKL GTP 15.7303
518 3GJX GTP 15.7407
519 4D0G GTP 15.942
520 2V7Q ATP 16
521 2CK3 ANP 16
522 2CK3 ADP 16
523 2V7Q ADP 16
524 1NRJ GTP 16.055
525 1GWN GTP 16.0976
526 3WY9 GDP 16.3594
527 3WYA GDP 16.3594
528 5UPK GNP 16.6667
529 3W5J GDP 16.6667
530 4QRH 0O2 16.6667
531 5YT0 GDP 16.7582
532 4X8O AP5 16.8224
533 1W4R TTP 16.9231
534 2W2X GSP 16.9355
535 5X40 ACP 17.4658
536 4TMZ GSP 17.6812
537 1KO8 6PG 17.7143
538 1YVD GNP 17.7515
539 2KIN ADP 18
540 2A9K GDP 18.3857
541 3WYG GTP 18.6813
542 2OBM ADP 18.732
543 2BEK ATP 19.0661
544 2CDN ADP 19.403
545 3DEF GDP 19.4656
546 4BAS GNP 19.598
547 5WRJ A3P 19.802
548 1W7J ADP BEF 19.8675
549 5XC5 GTP 19.8864
550 1G7C 5GP 20.2128
551 4KVG GTP 20.2381
552 3X1Z GNP 20.3593
553 4HDO GNP 20.3593
554 4HDQ GNP 20.3593
555 2A5J GDP 20.4188
556 1WF3 GNP 20.598
557 1GUA GNP 20.9877
558 2WJH GDP 21.0843
559 2WJH FLC 21.0843
560 4B47 GDP 21.2121
561 1Z0J GTP 22.0339
562 1M2O GNP 22.1053
563 5H1W LER 23.4483
564 5L3R GCP 23.588
565 4HI0 GDP 23.622
566 4MKF AP5 24.424
567 3GJ7 GDP 24.4344
568 3GJ0 GDP 24.4344
569 3GJ8 GDP 24.4344
570 3GJ4 GDP 24.4344
571 3GJ5 GDP 24.4344
572 3GJ3 GDP 24.4344
573 5UWQ GNP 24.4726
574 5UWU GNP 24.4726
575 5UWW GNP 24.4726
576 5DIF GNP 24.4726
577 5UWP GNP 24.4726
578 5DHF GNP 24.4726
579 5UWJ GNP 24.4726
580 6CIT GNP 24.4726
581 5UWO GNP 24.4726
582 5UWR GNP 24.4726
583 5UWI GNP 24.4726
584 5UWS GNP 24.4726
585 5UWT GNP 24.4726
586 5UWH GNP 24.4726
587 5DI9 GNP 24.4726
588 1Z06 GNP 24.8677
589 4MKG AP5 24.8848
590 2QTV GNP 25.1497
591 4NON GDP 25.3846
592 4R98 GNH 26.1993
593 1YZG GDP 26.257
594 1F6B GDP 26.2626
595 6G14 G4P 26.5306
596 4YLG GDP 27.1676
597 1WA5 GTP 27.2727
598 2A5F GTP 27.4286
599 5OCG GNP 27.5132
600 6BSX E7S 27.5281
601 6BSX GDP 27.5281
602 2QN6 GDP 27.7778
603 5TB5 GDP 28.1081
604 5TAR GDP 28.1081
605 3AQ4 GDP 28.2609
606 4ZI2 GNP 28.9474
607 3PCR GTP 29.0123
608 3A1S GDP 29.0698
609 4GOJ GNP 29.1005
610 2WIC GNP 29.2135
611 1ZJ6 G3D 29.4118
612 3N5C GDP 29.6296
613 2W83 GTP 29.697
614 4DID GDP 30.0518
615 4KAX GTP 30.1775
616 1FZQ GDP 30.3867
617 2X77 GDP 30.6878
618 6FA4 GNP 31.2139
619 4K81 GTP 31.5789
620 2C5L GTP 31.7919
621 5DI3 GNP 31.8919
622 2GJ8 ALF GDP 31.9767
623 5E95 GDP 32.1429
624 1LFD GNP 32.3353
625 6D5E GNP 32.3353
626 6D5J GNP 32.3353
627 6D59 GNP 32.3353
628 6D55 GNP 32.3353
629 6D56 GNP 32.3353
630 6D5V GNP 32.3353
631 6BVJ GNP 32.3353
632 6D5L GNP 32.3353
633 6BVL GNP 32.3353
634 6D5G GNP 32.3353
635 6D5H GNP 32.3353
636 6BVI GNP 32.3353
637 6BVK GNP 32.3353
638 6BVM GNP 32.3353
639 6D5M GNP 32.3353
640 5LEF GTP 32.4607
641 3KUD GDP 32.5301
642 3DDC GNP 32.5301
643 5WLB GNP 32.5301
644 2UZI GTP 32.5301
645 1WQ1 GDP 32.5301
646 1NVV GNP 32.5301
647 1CLU DBG 33.1325
648 1X1R GDP 33.1461
649 1D5C GDP 33.3333
650 5O2T GSP 33.7278
651 2FFQ GSP 35.0877
652 1SVI GDP 35.8974
653 2WJG GDP 36.1702
654 1ZD9 GDP 38.8298
655 5UQW GDP 39.1534
656 2ZEJ GDP 39.6739
657 5WDR GNP 39.7661
658 1MR3 G3D 40.3315
659 1R4A GNP 41.2121
660 4V0K GDP 42.0118
661 1TU3 GNP 42.1053
662 1R2Q GNP 42.3529
663 3MJH GTP 43.4524
664 1UPT GTP 43.8596
665 5EE5 GTP 44.4444
666 1RE0 GDP 45.122
667 1S9D GDP 45.122
668 2J59 GTP 45.7831
669 1J2J GTP 45.7831
670 1O3Y GTP 45.7831
Pocket No.: 2; Query (leader) PDB : 4DCT; Ligand: GDP; Similar sites found with APoc: 92
This union binding pocket(no: 2) in the query (biounit: 4dct.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1J0D 5PA 1.75953
2 3F8K COA 1.875
3 4ITM ATP 1.90476
4 4M52 M52 2.14592
5 4M52 FAD 2.14592
6 2A8X FAD 2.15517
7 4Z87 5GP 2.19298
8 2VWT PYR 2.24719
9 5EP2 AZU 2.34375
10 4YRY FAD 2.53623
11 1LVL FAD 2.63158
12 1KUV CA5 2.89855
13 3NOJ PYR 2.94118
14 1X8J A3P 3.1339
15 4UTG ANP 3.17919
16 3R96 ACO 3.19149
17 3R96 AMP 3.19149
18 1ZRH A3P 3.28467
19 1YKJ PHB 3.29949
20 1YKJ FAD 3.29949
21 2I4I AMP 3.35731
22 4AF0 IMP 3.50877
23 3CV2 OXL 3.50877
24 1CM0 COA 3.57143
25 1ME8 RVP 3.57853
26 1CJW COT 3.61446
27 2VHJ ADP 3.72807
28 1BOB ACO 3.75
29 4EBZ NAG NAG NAG NAG 3.77358
30 4CNK FAD 3.83632
31 3FV1 DYH 3.90625
32 4QC6 30N 3.91061
33 3FG2 FAD 3.9604
34 2ZW5 COA 3.98671
35 2ZPA ACO 4.16667
36 3RK1 ATP 4.21941
37 1K4M CIT 4.22535
38 5GK9 ACO 4.34783
39 4MOP 2H5 4.38596
40 4C2X NHW 4.39024
41 3TE4 ACO 4.65116
42 4TM3 FAD 4.74041
43 3D2M COA 4.82456
44 4EMI FAD 4.87805
45 4CRZ ACO 4.8951
46 1S7N COA 4.94506
47 5TVJ COA 4.9763
48 3KC1 2T6 5.04451
49 3E3U NVC 5.07614
50 3SXN COA 5.21327
51 5AHM IMP 5.25
52 4IXH IMP 5.26316
53 1PVN MZP 5.31915
54 5TQZ GLC 5.33333
55 3TO7 COA 5.43478
56 1PUA COA 5.52147
57 1IID NHM 5.6872
58 1P7T PYR 5.70175
59 5MU6 KFK 5.88235
60 5MU6 MYA 5.88235
61 1M5B BN1 6.08365
62 6FP4 FAD 6.18729
63 2R42 FPS 6.32911
64 4UWJ 7L5 6.38821
65 4UWJ MYA 6.38821
66 1D4O NAP 6.52174
67 5GLN XYS 7.55814
68 5GLN XYP XYP XYP 7.55814
69 2WSA 646 7.99087
70 2WSA MYA 7.99087
71 4KOT CE3 8.64198
72 5ODQ FAD 8.77193
73 5KF9 ACO 9.14634
74 1IYK MYA 9.43878
75 4HUT ATP 9.94764
76 4KVX ACO 10.2564
77 4EMJ FAD 10.2804
78 3WR7 COA 11.1765
79 4NSQ COA 12.1053
80 1IZC PYR 12.6844
81 4KWD JF2 13.6943
82 2F5Z FAD 14.0625
83 2YNC YNC 14.3229
84 2YNE YNE 14.3229
85 2YNE NHW 14.3229
86 5XXS COA 14.3939
87 2IL4 COA 14.5631
88 1H74 ADP 15.8784
89 5H67 ATP 16.25
90 5LS7 ACO 17.0732
91 1QHH ATP 17.3913
92 4PSW COA 23.6842
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