-->
Receptor
PDB id Resolution Class Description Source Keywords
4D7E 2.4 Å EC: 1.-.-.- AN UNPRECEDENTED NADPH DOMAIN CONFORMATION IN LYSINE MONOOXYGENASE NBTG FROM NOCARDIA FARCINICA NOCARDIA FARCINICA IFM 10152 OXIDOREDUCTASE LYSINE HYDROXYLASE FLAVIN-DEPENDENT MONOOXYN-HYDROXYLATING MONOOXYGENASES SIDEROPHORE C4A-HYDROPEROX
Ref.: AN UNPRECEDENTED NADPH DOMAIN CONFORMATION IN LYSIN MONOOXYGENASE NBTG PROVIDES INSIGHTS INTO UNCOUPLIN OXYGEN CONSUMPTION FROM SUBSTRATE HYDROXYLATION. J.BIOL.CHEM. V. 290 12676 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD C:500;
D:500;
A:500;
B:500;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4D7E 2.4 Å EC: 1.-.-.- AN UNPRECEDENTED NADPH DOMAIN CONFORMATION IN LYSINE MONOOXYGENASE NBTG FROM NOCARDIA FARCINICA NOCARDIA FARCINICA IFM 10152 OXIDOREDUCTASE LYSINE HYDROXYLASE FLAVIN-DEPENDENT MONOOXYN-HYDROXYLATING MONOOXYGENASES SIDEROPHORE C4A-HYDROPEROX
Ref.: AN UNPRECEDENTED NADPH DOMAIN CONFORMATION IN LYSIN MONOOXYGENASE NBTG PROVIDES INSIGHTS INTO UNCOUPLIN OXYGEN CONSUMPTION FROM SUBSTRATE HYDROXYLATION. J.BIOL.CHEM. V. 290 12676 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 318 families.
1 4D7E - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 4D7E - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 4D7E - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4D7E; Ligand: FAD; Similar sites found with APoc: 824
This union binding pocket(no: 1) in the query (biounit: 4d7e.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL GLC NBU None
2 2BOS GLA GAL GLC None
3 4J1Q NDP 0.932401
4 4A0S NAP 0.932401
5 5BUK FAD 1.1655
6 1Z45 NAD 1.1655
7 5A04 BGC 1.17994
8 5A04 NDP 1.17994
9 4DCM SAM 1.33333
10 4MIG G3F 1.3986
11 1ZGA SAH 1.40056
12 1PL6 NAD 1.40449
13 2ZXI FAD 1.41287
14 1FP2 SAH 1.42045
15 2XT3 ADP 1.45349
16 5I39 FAD 1.47059
17 5BW4 SAM 1.49813
18 1GY8 NAD 1.51134
19 1CDO NAD 1.60428
20 1HYH NAD 1.61812
21 3GDN FAD 1.6317
22 3GDN HBX 1.6317
23 3NT6 FAD 1.6317
24 2IZ1 ATR 1.6317
25 3NTA FAD 1.6317
26 3S1S SAH 1.6317
27 5TE1 7A2 1.6317
28 5Z21 NAI 1.67598
29 4J36 FAD 1.68675
30 4J36 1HR 1.68675
31 3LST SAH 1.72414
32 3U31 NAD 1.72414
33 5THY SAH 1.7284
34 2YYY NAP 1.74927
35 5A1T NAI 1.75953
36 3V1Y NAD 1.78042
37 5X68 FAD 1.79028
38 5KVA SAM 1.79856
39 1J49 NAD 1.8018
40 1V6A TRE 1.80723
41 6C8R SAH 1.84697
42 2VT3 ATP 1.86047
43 1BZL FAD 1.8648
44 1BZL GCG 1.8648
45 4AT0 FAD 1.8648
46 1FEC FAD 1.8648
47 2NPX NAD 1.8648
48 4EIP FAD 1.8648
49 2NPX FAD 1.8648
50 1MV8 NAD 1.8648
51 1P31 EPU 1.8648
52 4KRI SAH 1.8648
53 4AZW SAM 1.8648
54 4EIP K2C 1.8648
55 4EDF UPG 1.8648
56 1P3D UMA 1.8648
57 4ARE FLC 1.8648
58 3EF0 ALF 1.88172
59 4BJZ FAD 1.88679
60 4BJZ P3A 1.88679
61 1JAY NAP 1.88679
62 1I8T FAD 1.90736
63 5BJX NAD 1.91257
64 5BJX UDP 1.91257
65 5ZI9 FLC 1.92308
66 5DN9 NAD 1.92308
67 4USI AKG 1.94805
68 1N2X SAM 1.99336
69 1X7D NAD 2
70 5A96 GTP 2.00803
71 5E72 SAM 2.02312
72 2BKX F6R 2.06612
73 1LUA NAP 2.09059
74 1RYI GOA 2.09424
75 1RYI FAD 2.09424
76 5TS5 FAD 2.0979
77 4MOP 2H5 2.0979
78 1KNR FAD 2.0979
79 4C3Y FAD 2.0979
80 6F97 FAD 2.0979
81 1GPE FAD 2.0979
82 4C3Y ANB 2.0979
83 5JJR SAH 2.0979
84 1U2Z SAH 2.0979
85 3ULK NDP 2.0979
86 1M2W NAD 2.0979
87 1LJ8 NAD 2.0979
88 4N49 SAM 2.1028
89 5MGZ SAH 2.11864
90 5G48 1FL 2.13904
91 2CVQ NDP 2.14067
92 5ZXD ATP 2.1978
93 3RFV NAI 2.24719
94 3RFV 15L 2.24719
95 1UXG FUM 2.26537
96 1UXG NAD 2.26537
97 1I36 NAP 2.27273
98 4NEC SAH 2.27273
99 1VJT NAD 2.27743
100 4DMG SAM 2.29008
101 5DWQ SFG 2.29226
102 5DX1 SFG 2.29226
103 5DX8 SFG 2.29226
104 5DXA SFG 2.29226
105 5DX0 SFG 2.29226
106 6ARJ BW4 2.29226
107 6ARJ SAH 2.29226
108 1ORR NAD 2.30548
109 4R6W PC 2.32558
110 5YU3 PRO 2.32558
111 5YU3 NAD 2.32558
112 4R6W SAH 2.32558
113 1VQW FAD 2.331
114 2GVC FAD 2.331
115 2GV8 FAD 2.331
116 2C7G FAD 2.331
117 2C7G ODP 2.331
118 1DJN ADP 2.331
119 2GV8 NDP 2.331
120 5TDF 7A3 2.331
121 1VKO NAD 2.331
122 1L7E NAI 2.34375
123 1ZH8 NAP 2.35294
124 1XTP SAI 2.3622
125 3A06 NDP 2.39362
126 6FDF SAH 2.39521
127 3CMC NAD 2.39521
128 3G89 SAM 2.40964
129 4ZVV NAD 2.40964
130 4ZVV GN0 2.40964
131 5MPT SAH 2.41546
132 6GAS FAD 2.41692
133 1WP4 NDP 2.42215
134 4MO2 FAD 2.44565
135 4MO2 FDA 2.44565
136 4AVV CD 2.45098
137 1IM8 SAI 2.45902
138 5EOW FAD 2.46914
139 1F3L SAH 2.49221
140 1A5Z NAD 2.50784
141 1YKJ PHB 2.53807
142 1YKJ FAD 2.53807
143 3GGO NAI 2.54777
144 4U8P FDA 2.5641
145 4U8P UDP 2.5641
146 1Q1R FAD 2.5641
147 2AQJ FAD 2.5641
148 3OZ2 FAD 2.5641
149 2AQJ TRP 2.5641
150 4KRG SAH 2.5641
151 3QVP FAD 2.5641
152 1GQ2 NAP 2.5641
153 4Y30 49L 2.5641
154 4Y30 SAH 2.5641
155 1V8B NAD 2.5641
156 3VPH NAD 2.58065
157 2UYQ SAM 2.58065
158 3VPH OXM 2.58065
159 3KLJ FAD 2.5974
160 1F8G NAD 2.60417
161 5Z20 NAI 2.6087
162 5TWB FAD 2.61628
163 1LK7 DER 2.62009
164 3WBF NAP 2.62295
165 1RJW ETF 2.65487
166 5N6C NAD 2.66667
167 3L4S NAD 2.67857
168 3L4S 3PG 2.67857
169 3BGD SAH 2.69231
170 3BGD PM6 2.69231
171 2Q1W NAD 2.7027
172 1HDG NAD 2.71084
173 5THZ SAH 2.71605
174 4LWP SAH 2.71739
175 6B92 SAH 2.72109
176 4RPL FAD 2.75689
177 4RPL 3UC 2.75689
178 4USR FAD 2.77008
179 5KOK SAH 2.77078
180 3CIF NAD 2.78552
181 3CIF G3H 2.78552
182 3F8D FAD 2.78638
183 3ORF NAD 2.78884
184 2PXX SAH 2.7907
185 5JCA FAD 2.7972
186 5JCA NDP 2.7972
187 1H82 FAD 2.7972
188 1H82 GZZ 2.7972
189 1YQZ FAD 2.7972
190 1E1M NAP 2.7972
191 1E1M FAD 2.7972
192 4HA6 FAD 2.7972
193 5MZI FYK 2.7972
194 4YNU FAD 2.7972
195 5MZI FAD 2.7972
196 2DKH 3HB 2.7972
197 4YNU LGC 2.7972
198 2DKH FAD 2.7972
199 5Y77 FAD 2.7972
200 1MUU NAD 2.7972
201 2IXB NAD 2.7972
202 1GPM CIT 2.7972
203 2IXB A2G 2.7972
204 1GZ4 ATP 2.7972
205 3NJ4 NAD 2.7972
206 3NJ4 AFX 2.7972
207 3OND NAD 2.7972
208 3OND ADN 2.7972
209 1WD4 AHR 2.7972
210 1ZQ9 SAM 2.80702
211 1KJ8 GAR 2.8133
212 1RP0 AHZ 2.8169
213 1ELI PYC 2.82776
214 1EZ4 NAD 2.83019
215 3OA2 NAD 2.83019
216 1R6N 434 2.8436
217 1LSS NAD 2.85714
218 4TSK NDP 2.85714
219 3SSO SAH 2.86396
220 1UP7 NAD 2.8777
221 3TKA SAM 2.88184
222 5T52 NGA 2.89256
223 2FMD MAN MAN 2.91667
224 1P77 ATR 2.94118
225 5YEC ATP 2.94118
226 3V0H I3P 2.94985
227 5FUB SAH 2.96736
228 4GLL NAD 2.96736
229 4B4U NAP 2.9703
230 4ZCC FAD 2.97619
231 4ZCC NAI 2.97619
232 5D4V SAH 2.98507
233 3LZW NAP 3.01205
234 3LZW FAD 3.01205
235 3ABI NAD 3.0137
236 1Z3C SA8 3.02013
237 1PJS NAD 3.0303
238 2QA1 FAD 3.0303
239 1GTE FAD 3.0303
240 2IVD FAD 3.0303
241 5KOX FAD 3.0303
242 5KOX RFP 3.0303
243 2JHP SAH 3.0303
244 3DMH SAM 3.0303
245 1QMG APX 3.0303
246 3DMH GMP 3.0303
247 2RG0 CBI 3.0303
248 5MIT FAD 3.0581
249 5MIT NAP 3.0581
250 1EBF NAD 3.07263
251 4JK3 NAD 3.0888
252 4J4H 1J1 3.0888
253 4J4H NAI 3.0888
254 1I1N SAH 3.09735
255 1T26 NAI 3.10559
256 1T26 GBD 3.10559
257 5ZW3 SAH 3.11111
258 5N0J FAD 3.1339
259 1GZ6 NAI 3.1348
260 1L1E SAH 3.13589
261 1KPG SAH 3.13589
262 1KPH SAH 3.13589
263 3NYC IAR 3.14961
264 3NYC FAD 3.14961
265 1WG8 SAM 3.15789
266 2O4C NAD 3.15789
267 1TDF FAD 3.16456
268 1TDF NAP 3.16456
269 1LDN NAD 3.16456
270 1LDN OXM 3.16456
271 3GU3 SAH 3.16901
272 6GFK SAH 3.18725
273 2B4R NAD 3.18841
274 2B4R AES 3.18841
275 2GN4 UD1 3.19767
276 3Q87 SAM 3.2
277 2Q0L FAD 3.21543
278 2Q0L NAP 3.21543
279 1GV0 NAD 3.22581
280 5EES NAP 3.23887
281 3HAD NAD 3.24675
282 4IV9 FAD 3.2634
283 1COY FAD 3.2634
284 1COY AND 3.2634
285 5EB4 FAD 3.2634
286 3G5S FAD 3.2634
287 5FWA J7C 3.2634
288 1OBB NAD 3.2634
289 5NLM IOS 3.2634
290 4A59 AMP 3.2634
291 1NXJ TLA 3.27869
292 1O6Z NAD 3.30033
293 1W8D NAP 3.31126
294 1W73 NAP 3.31126
295 2DT5 NAD 3.31754
296 1NYT NAP 3.32103
297 1CER NAD 3.32326
298 1GAD NAD 3.33333
299 5K4G ASP 3.33333
300 3FPF TNA 3.3557
301 3FPF MTA 3.3557
302 5DM1 5D7 3.37079
303 5DM1 SAH 3.37079
304 1T9D P22 3.39734
305 3H5N ATP 3.39943
306 3CBG SAH 3.44828
307 5KMS FAD 3.45679
308 5KMS NAD 3.45679
309 6DNT NAD 3.48837
310 1RSG FAD 3.4965
311 1V59 FAD 3.4965
312 1REO FAD 3.4965
313 3IHG FAD 3.4965
314 1SQF SAM 3.4965
315 4DSG FAD 3.4965
316 4DSG UDP 3.4965
317 1O0S NAI 3.4965
318 1V59 NAD 3.4965
319 6F3N ADN 3.4965
320 4LHD GLY 3.4965
321 6F3N NAD 3.4965
322 6F3M NAD 3.4965
323 5W7M SAH 3.52564
324 6BYF CIT 3.52941
325 4D3F NAP 3.54839
326 6E8I PTR 3.5503
327 2F1K NAP 3.58423
328 1DSS NAD 3.6036
329 2P41 SAH 3.60656
330 1J0X NAD 3.61446
331 4WOH 4NP 3.61446
332 1WVG APR 3.62117
333 4ONQ SFG 3.64146
334 1L3I SAH 3.64583
335 3A25 SAM 3.65448
336 4EMI NAD 3.65854
337 4EMI FAD 3.65854
338 5HJM MTA 3.69318
339 2IID PHE 3.7296
340 2IID FAD 3.7296
341 1ZK7 FAD 3.7296
342 1NAA ABL 3.7296
343 1NAA 6FA 3.7296
344 3X0D SAH 3.7296
345 2CDU FAD 3.7296
346 4OPC FDA 3.7296
347 4OPC PGT 3.7296
348 2WPF FAD 3.7296
349 5BRT CH9 3.7296
350 5BRT FAD 3.7296
351 2WPF WPF 3.7296
352 5HSA FAS 3.7296
353 3LAD FAD 3.7296
354 2CDU ADP 3.7296
355 5EVY FAD 3.7296
356 3GDH SAH 3.73444
357 1X14 NAD 3.74065
358 4XFR CIT 3.74707
359 3H9E NAD 3.75723
360 3BXO SAM 3.76569
361 2DC1 NAD 3.81356
362 1MVQ MMA 3.81356
363 5CAE COA 3.83387
364 4ZRN UPG 3.84615
365 4ZRN NAD 3.84615
366 1RM4 NDP 3.85757
367 5GWX SAR 3.87324
368 5GWX SAM 3.87324
369 6CEP NAD 3.89222
370 5LKC FUC GLA A2G 3.8961
371 2OG2 MLI 3.89972
372 3DAG FEG 3.91061
373 3MB5 SAM 3.92157
374 4KIB SAH 3.92157
375 5X62 SAH 3.94089
376 1YJQ NAP 3.9604
377 3UCL NAP 3.9627
378 3UCL FAD 3.9627
379 3UCL CYH 3.9627
380 2BRY FAD 3.9627
381 1YY5 FAD 3.9627
382 4M52 FAD 3.9627
383 2A8X FAD 3.9627
384 4M52 M52 3.9627
385 3K7M FAD 3.9627
386 4TXI FAD 3.9627
387 2JJQ SAH 3.9627
388 5JWC FAD 3.9627
389 1UJ5 5RP 3.96476
390 3K5I AIR 3.97022
391 1SB8 NAD 3.97727
392 1SB8 UD2 3.97727
393 2RGJ FAD 3.9801
394 2GSD NAD 3.9801
395 2R4J 13P 3.99202
396 2R4J FAD 3.99202
397 2Q7V FAD 4
398 4POO SAM 4
399 6GAR FAD 4.01146
400 1KYQ NAD 4.0146
401 3A4T SFG 4.0146
402 3VSE SAH 4.0201
403 1OC2 NAD 4.02299
404 1OC2 TDX 4.02299
405 2EG5 SAH 4.03226
406 5UAV NDP 4.03727
407 5UAV TFB 4.03727
408 6AM8 TRP 4.0404
409 2NAD NAD 4.07125
410 3O7W SAM 4.08163
411 1U1I NAD 4.08163
412 2J5V PCA 4.08719
413 5N53 8NB 4.10256
414 3EB9 FLC 4.13534
415 1UDB UFG 4.14201
416 1UDB NAD 4.14201
417 1R6D NAD 4.1543
418 1R6D DAU 4.1543
419 4M73 SAH 4.1543
420 4L8V NAP 4.1543
421 4M73 M72 4.1543
422 1KEW NAD 4.15512
423 1KEW TYD 4.15512
424 2EFJ SAH 4.16667
425 2F5X ASP 4.16667
426 5LD5 NAD 4.18994
427 5FJN FAD 4.1958
428 5YB7 ORN 4.1958
429 5YB7 FAD 4.1958
430 5FJN BE2 4.1958
431 3PT9 SAH 4.1958
432 4HXY NDP 4.1958
433 1ZEM NAD 4.19847
434 3FG2 FAD 4.20792
435 1I2B NAD 4.20792
436 1I2B USQ 4.20792
437 1I2B UPG 4.20792
438 2D2I NAP 4.21053
439 5NUF NAD 4.21687
440 5NUE NAD 4.21687
441 3QOX SAH 4.22535
442 5F8F SFG 4.24403
443 2BZG SAH 4.31034
444 2DFV NAD 4.32277
445 3G2O SAM 4.34783
446 5M58 SAH 4.34783
447 3LKZ SFG 4.36137
448 2PV7 NAD 4.36242
449 2FK8 SAM 4.40252
450 1VE3 SAM 4.40529
451 3B20 NAD 4.42478
452 4JX1 CAH 4.42478
453 3B1J NAD 4.42478
454 2XVF FAD 4.4289
455 1X87 NAD 4.4289
456 4WBD CIT 4.4289
457 3OJO NAD 4.4289
458 5J3R GSH 4.4335
459 2VDV SAM 4.47154
460 1FWV SGA MAG FUC 4.47761
461 1RKX NAD 4.48179
462 2VYN NAD 4.49102
463 3KB6 NAD 4.49102
464 2GLX NDP 4.51807
465 4YMH SAH 4.58333
466 3DXY SAM 4.58716
467 2HNK SAH 4.60251
468 3GWZ SAH 4.60705
469 3GXO SAH 4.60705
470 2WK1 SAH 4.60993
471 3NOJ PYR 4.62185
472 2PWY SAH 4.65116
473 5TUK FAD 4.65686
474 2NVK NAP 4.662
475 2XVE FAD 4.662
476 3E1T FAD 4.662
477 1PN0 FAD 4.662
478 4C4A SAH 4.662
479 1PN0 IPH 4.662
480 2NVK FAD 4.662
481 1PS9 FAD 4.662
482 4RSL FAD 4.662
483 1PS9 NAP 4.662
484 4M37 SAH 4.66472
485 1SC6 NAD 4.70297
486 1DLJ NAI 4.72637
487 3ITJ FAD 4.73373
488 3ITJ CIT 4.73373
489 1J5P NAD 4.74308
490 5O4J 9KH 4.74453
491 5O4J SAH 4.74453
492 5O4J PJL 4.74453
493 3GRU AMP 4.74576
494 2YX1 SFG 4.7619
495 3QXV MTX 4.7619
496 4NTC FAD 4.77612
497 4IF4 BEF 4.80769
498 5ULP KB1 4.85075
499 5CUQ NSC 4.86891
500 1EK6 UPG 4.88506
501 1EK6 NAI 4.88506
502 5TUF TDC 4.88998
503 5TUF FAD 4.88998
504 5OC1 FAD 4.8951
505 5DNK SAH 4.8951
506 1UWK URO 4.8951
507 1UWK NAD 4.8951
508 5TSH ANP 4.8951
509 1HDR NAD 4.91803
510 4JJF FE9 4.94186
511 4P83 U5P 4.94506
512 5JE8 NAD 4.96689
513 1D1Q 4NP 4.96894
514 3HVJ 705 4.97738
515 5TVA AMP 5
516 1PD2 GSH 5.02513
517 5DZ2 212 5.02959
518 1DL5 SAH 5.04732
519 4KOA NDP 5.1051
520 2RI1 GLP 5.10638
521 5O42 NAD 5.10949
522 5O42 BGC 5.10949
523 5O42 9JW 5.10949
524 4D04 FAD 5.12821
525 4D04 NAP 5.12821
526 3AYI FAD 5.12821
527 3AYI HCI 5.12821
528 3GF4 UPG 5.12821
529 3GF4 FAD 5.12821
530 3FUU ADN 5.16605
531 3VYW SAM 5.19481
532 3N8K D1X 5.23256
533 4UTU LRY 5.24017
534 4UTW RFW 5.24017
535 6AIN FAD 5.26316
536 3HDY FDA 5.28967
537 3HDY GDU 5.28967
538 3HDY FAD 5.28967
539 2EJU SAH 5.29101
540 1LTH NAD 5.32915
541 5TQZ GLC 5.33333
542 1CF2 NAP 5.34125
543 5J5Z FAD 5.36131
544 5WGR FAD 5.36131
545 2GMH FAD 5.36131
546 2F5Z FAD 5.36131
547 1RM0 D6P 5.36131
548 1RM0 NAI 5.36131
549 5MW4 5JU 5.38922
550 1QAW TRP 5.40541
551 2WA2 SAM 5.43478
552 4OBW SAM 5.44747
553 5E9W SAH 5.44872
554 5E8J SAH 5.44872
555 5W7K SAH 5.44872
556 2AOT SAH 5.47945
557 1JQD SAH 5.47945
558 1GUZ NAD 5.48387
559 3WV8 ATP 5.50459
560 3B1F NAD 5.51724
561 1XCL SAH 5.53191
562 3MAG SAH 5.53746
563 4USS GSH 5.53846
564 1EJ0 SAM 5.55556
565 3OFK SAH 5.55556
566 2Q1S NAI 5.57029
567 1TPY SAH 5.57491
568 5FA8 SAM 5.59006
569 1MO9 FAD 5.59441
570 1MO9 KPC 5.59441
571 3NKS FAD 5.59441
572 2VTD LKM 5.59441
573 1WOQ BGC 5.61798
574 6AA8 NAD 5.62914
575 1W6U NAP 5.62914
576 1C3X 8IG 5.6391
577 4IWN GEK 5.67686
578 1I9G SAM 5.71429
579 3MCT SAH 5.72391
580 3RKR NAP 5.72519
581 2VOH CIT 5.73248
582 2XYQ SAH 5.7377
583 1Y8Q ATP 5.78035
584 6ACS CIT 5.81395
585 3EGI ADP 5.82524
586 2YG3 FAD 5.82751
587 5MBX SP5 5.82751
588 5MBX FAD 5.82751
589 5ZYN FAD 5.82751
590 1WDK NAD 5.82751
591 5WP5 SAH 5.82751
592 3NTD FAD 5.82751
593 5WP4 SAH 5.82751
594 5AHN IMP 5.82751
595 2A92 NAI 5.919
596 4XUC SAM 5.9633
597 4XUC 43G 5.9633
598 1GR0 NAD 5.99455
599 3GFB NAD 6
600 3GCZ SAM 6.02837
601 1VL1 CIT 6.03448
602 1LVL FAD 6.06061
603 4YKG FAD 6.06061
604 4YKG NAD 6.06061
605 1LVL NAD 6.06061
606 3SQP FAD 6.06695
607 1G8S MET 6.08696
608 3QV1 NAD 6.09756
609 2YVF FAD 6.12745
610 2YVF NAD 6.12745
611 6DWI HD4 6.17284
612 3KIH GDL 6.18557
613 1E6E FAD 6.25
614 4RDH AMP 6.25
615 4RDI ATP 6.25
616 1WY7 SAH 6.28019
617 1JNR FAD 6.29371
618 5XNC MTA 6.29371
619 1Q19 SSC 6.29371
620 3BBH SFG 6.34146
621 4UP3 FAD 6.36943
622 4UP3 NDP 6.36943
623 2YY7 NAD 6.41026
624 1L5Y BEF 6.45161
625 4JNA FAD 6.47059
626 3NUG NAD 6.47773
627 4D79 ATP 6.52174
628 4XZ3 COA 6.52174
629 2VSS V55 6.52174
630 1P1C SAH 6.53266
631 1G60 SAM 6.53846
632 3ZNN FAD 6.62824
633 3ZNN 4WL 6.62824
634 2DPM SAM 6.69014
635 2RGO FAD 6.75991
636 5JCM NAD 6.75991
637 5JCM ISD 6.75991
638 5JCM FAD 6.75991
639 3X0V FAD 6.75991
640 2WME NAP 6.75991
641 4REP FAD 6.86869
642 3ZF8 GDP 6.88525
643 3H2B SAH 6.89655
644 2HK9 ATR 6.90909
645 2HK9 NAP 6.90909
646 1NE7 AGP 6.92042
647 4RQU NAD 6.93333
648 1QAN SAH 6.96721
649 1BXK NAD 7.04225
650 3T7S SAM 7.08955
651 2FWP ICR 7.10383
652 2FWP CIT 7.10383
653 5EZ7 FAD 7.14286
654 1C0I BE2 7.16253
655 1C0I FAD 7.16253
656 4BVA NDP 7.16418
657 2PT9 S4M 7.16511
658 1D4D FAD 7.16783
659 3KU0 ADE 7.17131
660 1O94 ADP 7.19697
661 1QO8 FAD 7.22611
662 1Q9I TEO 7.22611
663 1Q9I FAD 7.22611
664 3L9W GSH 7.26392
665 3L9W AMP 7.26392
666 1I1Q TRP 7.29167
667 1BXG NAD 7.30337
668 1BW9 NAD 7.30337
669 1C1X NAD 7.32394
670 5BVA FAD 7.33496
671 3JWH SAH 7.37327
672 1NM5 NAD 7.38916
673 2ZIF SAM 7.40741
674 2RGH FAD 7.45921
675 2CDN ADP 7.46269
676 4USQ FAD 7.47922
677 4Z0H NAD 7.48503
678 1R18 SAH 7.48899
679 3TLJ SAH 7.5067
680 1H5R THM 7.50853
681 5UAO FAD 7.57856
682 3OZG SSI 7.6
683 3DUW SAH 7.62332
684 3LCC SAH 7.65957
685 2VVM FAD 7.69231
686 2VVL FAD 7.69231
687 5AYV NAP 7.76699
688 1SOW NAD 7.92683
689 3FPZ AHZ 7.97546
690 4YSX FAD 7.97872
691 2XVM SAH 8.0402
692 4TQG NDP 8.04954
693 3ENV ABF 8.08511
694 3A27 SAM 8.08823
695 2I7C AAT 8.12721
696 4JDR FAD 8.15851
697 2JB2 PHE 8.15851
698 2JB2 FAD 8.15851
699 4XQC 13D 8.15851
700 4XQC NAD 8.15851
701 4YCA NDP 8.16327
702 2G5C NAD 8.18505
703 5H81 NAP 8.22622
704 2NXE SAM 8.26772
705 5NM7 GLY 8.27068
706 5UR0 NAD 8.30946
707 4FZV SAM 8.3682
708 1OMO NAD 8.38509
709 1FL2 FAD 8.3871
710 2E5V FAD 8.39161
711 9LDT OXM 8.43373
712 9LDB NAD 8.43373
713 9LDT NAD 8.43373
714 1G55 SAH 8.45481
715 1Q0S SAH 8.49421
716 3H8V ATP 8.56164
717 5LOG SAH 8.58369
718 2OOR NAD 8.62069
719 5AHO TLA 8.63095
720 4GKV NAD 8.63095
721 3WGT QSC 8.64553
722 3WGT FAD 8.64553
723 2NU8 COA 8.68056
724 1VDC FAD 8.70871
725 6BQ6 TER 8.76133
726 1KYZ SAH 8.76712
727 5YF1 SFG 8.83978
728 5YF1 8V0 8.83978
729 5L95 AMP 8.96057
730 4JCA CIT 8.98204
731 2HMT NAI 9.02778
732 3QH2 3NM 9.04977
733 5N2I NAP 9.05172
734 1NVT NAP 9.05923
735 1NW5 SAM 9.09091
736 3C6K MTA 9.18635
737 3C6K SPD 9.18635
738 1NVM NAD 9.29487
739 5ZBC FAD 9.32401
740 5WS9 AMP 9.32401
741 3SAO DBH 9.375
742 5G3U FDA 9.45626
743 5G3U ITW 9.45626
744 1HKU NAD 9.49721
745 3FZG SAM 9.5
746 4AP3 NAP 9.55711
747 4AP3 FAD 9.55711
748 5LQ8 GB 9.57447
749 5ZZ6 NAD 9.61539
750 5ZZ6 ADP 9.61539
751 4QTU SAM 9.62963
752 5N5D SAM 9.73451
753 5GZ6 NDP 9.81595
754 5GZ6 7C3 9.81595
755 2O07 MTA 9.86842
756 2O07 SPD 9.86842
757 2YVJ FAD 10.0917
758 2YVJ NAI 10.0917
759 3AD8 PYC 10.101
760 3AD8 FAD 10.101
761 3AD8 NAD 10.101
762 1NV8 MEQ 10.2113
763 1NV8 SAM 10.2113
764 3AB1 FAD 10.2778
765 4EMJ FAD 10.2804
766 2Y6Q I7T 10.3015
767 2Y6Q FAD 10.3015
768 3RNM FAD 10.3448
769 2D2F ADP 10.4
770 5ERG SAM 10.4895
771 1O8B ABF 10.5023
772 6FP4 E1T 10.7226
773 6FP4 FAD 10.7226
774 3A75 GLU 10.8108
775 1JQ3 AAT 10.8108
776 3CYI ATP 10.9091
777 2Q28 ADP 10.9557
778 4MCC 21X 10.9756
779 2JBH 5GP 11.1111
780 43CA NPO 11.1111
781 5YRL GLC GLC 11.2676
782 3QJ4 FAD 11.4035
783 4J56 FAD 11.8299
784 4II2 ATP 12.0482
785 5JE0 AZ8 12.1457
786 5JE0 SAH 12.1457
787 4YUW 4JU 12.5
788 3TKY SAH 12.5
789 4YUW S4M 12.5
790 4CNK FAD 12.532
791 2VWT PYR 12.7341
792 5VJN IR8 12.8342
793 5NA1 FAD 12.9902
794 6F5Z SAH 13.1148
795 1GET FAD 13.5198
796 1GET NAP 13.5198
797 2PZM UDP 13.6364
798 2PZM NAD 13.6364
799 6BWL NAD 13.7195
800 2GND MAN 14.2857
801 2GMM MAN MAN 14.2857
802 3QFA FAD 14.6552
803 2HQM FAD 15.0313
804 5E5U MLI 15.5779
805 6DUB SAH 15.7658
806 3LU1 NAD 15.9341
807 5Z84 CHD 16.4706
808 6D6Y SAH 16.5501
809 5U8U FAD 16.7832
810 4TM3 FAD 17.4825
811 5Y8L HUI 17.9661
812 5Y8L NAD 17.9661
813 1VI2 NAD 18
814 1GXU 2HP 18.6813
815 1NPD NAD 18.75
816 5ODQ FAD 19.244
817 2FKA BEF 23.2558
818 1JG3 ADN 25.1064
819 3S5W FAD 26.3403
820 3S5W NAP 26.3403
821 2ZFU SAH 28.8372
822 4GQB 0XU 36.3636
823 4M38 SAH 38.0952
824 5FA5 MTA 40
Pocket No.: 2; Query (leader) PDB : 4D7E; Ligand: FAD; Similar sites found with APoc: 82
This union binding pocket(no: 2) in the query (biounit: 4d7e.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 1FUR MLT 1.1655
2 1SJD NPG 1.63043
3 2GK6 ADP 1.6317
4 1H2B NAJ 1.67131
5 3B8I OXL 1.74216
6 6EL3 NAP 1.83727
7 2VHW NAI 1.85676
8 4IX4 ADP 2
9 3I53 SAH 2.10843
10 3O5X JZG 2.17391
11 5FBF DCM 2.24719
12 1KEV NDP 2.2792
13 3CB2 GDP 2.5641
14 4JGT PYR 2.67559
15 5A1S FLC 2.7972
16 3RC3 ANP 2.7972
17 5T52 A2G 2.89256
18 3C3Y SAH 2.95359
19 1BGV GLU 3.0303
20 2GN4 NDP 3.19767
21 3B6O TMP 3.23887
22 4WOE ADP 3.2634
23 5AJU RP5 3.28467
24 1FDJ 2FP 3.30579
25 1T9D PYD 3.39734
26 1KC7 PPR 3.4965
27 1Z03 OCH 3.4965
28 1M2K APR 3.61446
29 2E2P ADP 3.67893
30 1D1T NAD 3.75335
31 3BEO UDP 4
32 3EVG SAH 4
33 1O5I NAD 4.01606
34 4DPL NAP 4.17827
35 4MDH NAD 4.19162
36 4PPF FLC 4.28571
37 3RI1 3RH 4.47284
38 2B99 RDL 4.48718
39 3FXU TSU 4.59016
40 3B9Q MLI 4.63576
41 2B6N ALA PRO THR 4.67626
42 1DLJ UGA 4.72637
43 4O48 ASP 4.81928
44 3FIU POP 5.22088
45 4YDS ATP 5.26316
46 1R37 NAD 5.36131
47 4RI1 ACO 5.37634
48 5OVK NDP 5.46875
49 4RHS SIA SIA GAL 5.7377
50 4ZNO SUC 5.97015
51 1IZC PYR 6.19469
52 4PZ6 GMP 6.20347
53 1YXM ADE 6.27063
54 2FR1 NDP 6.29371
55 4L8F MTX 6.41026
56 2NSJ C2R 6.50888
57 4CQM NAP 6.89655
58 6HKE MLT 6.91824
59 6HKE LMR 6.91824
60 2YKX AKG 6.99301
61 3RGQ 5P5 7.69231
62 1KYV RBF 8.1761
63 2OOR TXP 8.62069
64 4N2R FUB 8.68263
65 5Z3I ADE 9.0566
66 5EIN NAP 9.25926
67 6C5B SAH 9.38416
68 2DTJ THR 9.55056
69 3JQM GTP 9.55414
70 2A9W GA9 9.84848
71 1MRH FMC 9.88593
72 1J78 OLA 11.4219
73 2UVO NAG 11.6959
74 2UVO NDG 11.6959
75 4CNK MEU 12.532
76 2HYQ MAN MAN 13.1148
77 2NUO BGC 13.1148
78 3ZO7 K6H 13.8298
79 2GNB MAN 14.2857
80 1L7N ALF 14.6919
81 2ZL4 ALA ALA ALA ALA 18.3673
82 5ODQ 9SB 19.244
Pocket No.: 3; Query (leader) PDB : 4D7E; Ligand: FAD; Similar sites found with APoc: 34
This union binding pocket(no: 3) in the query (biounit: 4d7e.bio2) has 35 residues
No: Leader PDB Ligand Sequence Similarity
1 2OKK ABU 1.1655
2 2NZ2 ASP 1.45278
3 5CX6 CDP 1.6317
4 5Z21 OXM 1.67598
5 1F20 NAP 1.8648
6 5KVS NAP 2.07792
7 4P6G 2FZ 2.21239
8 1SQ5 PAU 2.27273
9 5WQJ 7N3 2.3569
10 3THR C2F 2.38908
11 4RDN 6MD 2.39521
12 3MQ2 SAH 2.75229
13 1GPM AMP 2.7972
14 4RF7 ARG 3.0303
15 3C7A NAD 3.46535
16 5OFW 9TW 3.58744
17 2OEM 1AE 3.63196
18 1M0S CIT 3.65297
19 6EYT NDG 3.66972
20 5HZ9 5M8 3.7037
21 4UP4 NDG 3.74065
22 2WDQ CBE 4.65116
23 2GJP MAL 4.662
24 3QDK QDK 4.662
25 1GVF PGH 4.8951
26 2OFW ADX 5.28846
27 1FP1 SAH 5.37634
28 2WW5 CHT 6.29371
29 3F81 STT 7.65027
30 4N2R AHR 8.68263
31 4X60 3XV 10.8571
32 4X60 SFG 10.8571
33 1L7P SEP 15.1659
34 5W97 CHD 16.4706
Pocket No.: 4; Query (leader) PDB : 4D7E; Ligand: FAD; Similar sites found with APoc: 26
This union binding pocket(no: 4) in the query (biounit: 4d7e.bio2) has 36 residues
No: Leader PDB Ligand Sequence Similarity
1 3ZH4 FLC 1.67064
2 4A3X LAT 2.20264
3 6GKV SAH 2.2792
4 1F8F NAD 2.42588
5 3GGO ENO 2.54777
6 3IWJ NAD 2.5641
7 1ZOS MTM 2.6087
8 1DKU AP2 2.83912
9 4WOE 3S5 3.2634
10 5DF1 NAP 3.53261
11 5DF1 58X 3.53261
12 5BSZ SAH 3.6
13 3MA0 XYP 4.15335
14 1QCI ADE 4.19847
15 4RKK GLC GLC GLC GLC GLC GLC 4.21687
16 2RBK VN4 4.5977
17 1FQK ALF 5.23077
18 5YSI NCA 5.26316
19 5E1M SAH 5.39419
20 6CZ7 MGD 7.69231
21 1EJH M7G 11.0526
22 5YRG BGC GLC 11.2676
23 5YRJ BGC GLC 11.2676
24 1VJE MSE 11.4458
25 5OFI 9TQ 20.4918
26 5CLO NS8 22.0339
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