Receptor
PDB id Resolution Class Description Source Keywords
4BME 2 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE N TERMINAL DOMAIN OF HUMAN GALECTIN 8, F19Y MUTANT HOMO SAPIENS SUGAR BINDING PROTEIN CARBOHYDRATE RECOGNITION
Ref.: NATURAL SINGLE AMINO ACID POLYMORPHISM (F19Y) IN HU GALECTIN-8: DETECTION OF STRUCTURAL ALTERATIONS AND INCREASED GROWTH-REGULATORY ACTIVITY ON TUMOR CELLS FEBS J. V. 281 1446 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LBT B:1154;
A:1156;
Valid;
Valid;
none;
none;
Ka = 13000 M^-1
342.296 C12 H22 O11 C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5T7I 2 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF GALECTIN-8N IN COMPLEX WITH LNNT HOMO SAPIENS CARBOHYDRATE-BINDING PROTEIN GALECTIN-8 LECTIN SUGAR BINDIPROTEIN
Ref.: STRUCTURE-BASED RATIONALE FOR DIFFERENTIAL RECOGNIT LACTO- AND NEOLACTO- SERIES GLYCOSPHINGOLIPIDS BY T N-TERMINAL DOMAIN OF HUMAN GALECTIN-8. SCI REP V. 6 39556 2016
Members (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
2 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
3 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
4 3VKO - SIA GAL NAG n/a n/a
5 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
6 5T7T Kd = 2.1 uM GAL NAG n/a n/a
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
2 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
3 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
4 3VKO - SIA GAL NAG n/a n/a
5 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
6 5T7T Kd = 2.1 uM GAL NAG n/a n/a
7 4WVV - LBT C12 H22 O11 C([C@@H]1[....
8 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
50% Homology Family (94)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 5NF9 Kd = 4.7 uM 8VW C22 H32 N2 O12 CC(=O)N[C@....
2 5E8A Kd = 0.034 uM 5KS C28 H30 F2 N6 O8 S c1cc(ccc1c....
3 1A3K - GAL NAG n/a n/a
4 3T1M Kd = 0.91 mM DQT C23 H27 N O7 Cc1ccc(cc1....
5 4LBL Kd = 11 uM BGC SIA GAL n/a n/a
6 2NMN Kd = 260 uM GAL BGC n/a n/a
7 4R9B - LAT C12 H22 O11 C([C@@H]1[....
8 2NN8 Kd = 260 uM LAT C12 H22 O11 C([C@@H]1[....
9 4JC1 Kd = 50 uM TDG C12 H22 O10 S C([C@@H]1[....
10 4R9A - LAT C12 H22 O11 C([C@@H]1[....
11 5EXO - 5SY C19 H22 O9 CC(=O)O[C@....
12 5E88 Kd = 0.065 uM 5KT C24 H28 N6 O8 S3 c1cscc1c2c....
13 4R9D - LAT C12 H22 O11 C([C@@H]1[....
14 1KJL Kd = 67 uM GAL NAG n/a n/a
15 3T1L Kd = 0.55 mM MQT C17 H22 O8 Cc1ccc(cc1....
16 2XG3 Kd = 18.2 uM UNU GAL NAG n/a n/a
17 4LBJ Kd = 0.39 uM GAL NAG GAL BGC n/a n/a
18 4R9C - LAT C12 H22 O11 C([C@@H]1[....
19 3ZSJ Kd = 231 uM LAT C12 H22 O11 C([C@@H]1[....
20 4LBM Kd = 0.97 uM BGC GAL NAG GAL n/a n/a
21 1KJR Kd = 0.88 uM BEK GAL NAG n/a n/a
22 3AYE - LAT C12 H22 O11 C([C@@H]1[....
23 5E89 Kd = 0.014 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
24 4LBO Kd = 1.7 uM BGC GAL SIA n/a n/a
25 2NMO Kd = 260 uM GAL BGC n/a n/a
26 3AYC Kd = 57 uM GAL NGA GAL BGC SIA n/a n/a
27 4JCK Kd = 4.3 mM 1LL C12 H22 O10 S C([C@@H]1[....
28 5NFA Kd = 5.6 uM 8VQ C24 H36 N2 O12 CC(=O)N[C@....
29 4LBK Kd = 0.32 uM GAL NAG GAL BGC n/a n/a
30 4RL7 - LAT C12 H22 O11 C([C@@H]1[....
31 3AYD Kd = 65 uM NPO A2G GAL n/a n/a
32 4LBN Kd = 0.65 uM GLC GAL NAG GAL n/a n/a
33 2D6N - GAL NAG n/a n/a
34 2D6M - LBT C12 H22 O11 C([C@@H]1[....
35 2D6O - NAG GAL GAL NAG n/a n/a
36 4XBN Kd = 93 uM GAL NAG n/a n/a
37 5H9R Kd = 0.84 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
38 5H9P Kd = 0.068 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
39 5DG2 - GAL GLC n/a n/a
40 5EWS - GAL BGC n/a n/a
41 4XBL Kd = 340 uM GAL NAG n/a n/a
42 4Y24 Kd = 0.22 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
43 3T2T - MQT C17 H22 O8 Cc1ccc(cc1....
44 3OY8 Kd = 220 uM GAL GCO n/a n/a
45 2EAL - GAL NGA A2G n/a n/a
46 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
47 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
48 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
49 2ZHM - NAG GAL GAL NAG GAL n/a n/a
50 2EAK - LBT C12 H22 O11 C([C@@H]1[....
51 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
52 5H9S Kd = 87 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
53 5H9Q Kd = 38 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
54 4XBQ Kd = 270 uM GAL NAG n/a n/a
55 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
56 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
57 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
58 3VKO - SIA GAL NAG n/a n/a
59 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
60 5T7T Kd = 2.1 uM GAL NAG n/a n/a
61 3I8T Kd = 600 uM LBT C12 H22 O11 C([C@@H]1[....
62 3WV6 - GAL BGC n/a n/a
63 3NV2 - GAL NDG n/a n/a
64 3NV4 - SIA GAL BGC n/a n/a
65 3NV3 - GAL NAG MAN n/a n/a
66 3WUD Kd = 41 uM GLC GAL n/a n/a
67 3GAL - 1GN C6 H13 N O5 C([C@@H]1[....
68 4UW6 - VV7 C69 H73 N20 O39 [H]1c2c(cc....
69 2GAL - GAL C6 H12 O6 C([C@@H]1[....
70 4GAL - GAL BGC n/a n/a
71 4UW3 - 50G C31 H50 N10 O18 c1c(nnn1[C....
72 4UW4 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
73 3ZXE Kd = 450 uM PGZ C22 H28 N O8 P S Cc1ccc(cc1....
74 5GAL - NAG GAL n/a n/a
75 4UW5 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
76 1GAN - NDG GAL n/a n/a
77 1A78 - TDG C12 H22 O10 S C([C@@H]1[....
78 5DUW Kd = 510 uM 5GO C12 H22 O14 S C([C@@H]1[....
79 5DUV Kd = 1300 uM LAT C12 H22 O11 C([C@@H]1[....
80 5DUX Kd = 380 uM LAT FUC n/a n/a
81 4WVV - LBT C12 H22 O11 C([C@@H]1[....
82 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
83 4YLZ Kd = 270 uM LAT NAG GAL n/a n/a
84 5CBL - LAT C12 H22 O11 C([C@@H]1[....
85 4YM2 Kd = 1400 uM SGA BGC n/a n/a
86 4YM3 Kd = 1900 uM LAT C12 H22 O11 C([C@@H]1[....
87 4YM1 Kd = 580 uM LAT FUC n/a n/a
88 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
89 1WLD - GAL BGC n/a n/a
90 5NFB Kd = 0.77 uM 8VT C30 H40 N2 O13 CC(=O)N[C@....
91 5NF7 Kd = 37.5 uM 8VZ C16 H28 N2 O11 CC(=O)N[C@....
92 1SLB - NAG MAN GAL MAN MAN NAG GAL n/a n/a
93 1SLT - NDG GAL n/a n/a
94 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LBT; Similar ligands found: 339
No: Ligand ECFP6 Tc MDL keys Tc
1 LBT 1 1
2 GLC BGC 1 1
3 MAL MAL 1 0.970588
4 BGC GLC 1 1
5 CBI 1 1
6 GAL BGC 1 1
7 CBK 1 1
8 BGC BMA 1 1
9 N9S 1 1
10 GLA GLA 1 1
11 BGC GAL 1 1
12 GAL GLC 1 1
13 GLC GAL 1 1
14 BMA BMA 1 1
15 GLA GAL 1 1
16 BMA GAL 1 1
17 LAT 1 1
18 MAB 1 1
19 MAL 1 1
20 B2G 1 1
21 CEX 0.909091 1
22 BGC GLC GLC GLC GLC 0.909091 1
23 GLC GLC GLC GLC GLC 0.909091 1
24 CTR 0.909091 1
25 MTT 0.909091 1
26 CE5 0.909091 1
27 BMA BMA BMA BMA BMA 0.909091 1
28 CTT 0.909091 1
29 CT3 0.909091 1
30 GLC GLC GLC GLC GLC GLC GLC 0.909091 1
31 BGC GLC GLC GLC GLC GLC GLC 0.909091 1
32 BGC BGC BGC GLC 0.909091 1
33 CEY 0.909091 1
34 MAN MAN BMA BMA BMA BMA 0.909091 1
35 BMA BMA BMA 0.909091 1
36 B4G 0.909091 1
37 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.909091 1
38 GLC GAL GAL 0.909091 1
39 GLA GAL GLC 0.909091 1
40 GAL GAL GAL 0.909091 1
41 MAN BMA BMA BMA BMA 0.909091 1
42 MLR 0.909091 1
43 CE8 0.909091 1
44 MT7 0.909091 1
45 CE6 0.909091 1
46 GLC BGC BGC BGC BGC BGC 0.909091 1
47 GLC GLC BGC 0.909091 1
48 GLC BGC BGC 0.909091 1
49 GLC BGC GLC 0.909091 1
50 BMA MAN BMA 0.909091 1
51 GLC GLC BGC GLC GLC GLC GLC 0.909091 1
52 BGC GLC GLC 0.909091 1
53 BGC GLC GLC GLC 0.909091 1
54 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
55 DXI 0.909091 1
56 BMA BMA BMA BMA BMA BMA 0.909091 1
57 GLC GLC GLC GLC GLC GLC GLC GLC 0.909091 1
58 GLC BGC BGC BGC BGC 0.909091 1
59 BGC BGC BGC BGC BGC BGC 0.909091 1
60 MAN BMA BMA 0.909091 1
61 MAN BMA BMA BMA BMA BMA 0.833333 0.970588
62 BMA BMA BMA BMA BMA BMA MAN 0.833333 0.970588
63 GLA GAL GAL 0.816327 1
64 GLA GAL BGC 0.816327 1
65 BGC BGC BGC BGC 0.754717 1
66 BGC BGC BGC BGC BGC BGC BGC BGC 0.754717 1
67 BMA BMA GLA BMA BMA 0.689655 1
68 LAT GLA 0.680851 1
69 GLC GLC GLC BGC 0.672414 1
70 BGC BGC GLC 0.660377 1
71 U63 0.647059 0.891892
72 DR5 0.64 0.942857
73 MMA MAN 0.64 0.942857
74 GLA EGA 0.634615 0.942857
75 BMA BMA MAN 0.615385 0.970588
76 GAL FUC 0.615385 0.941176
77 BGC BGC 0.612245 1
78 MAN MAN 0.612245 1
79 2M4 0.612245 1
80 GLC GAL FUC 0.610169 0.970588
81 GLC GLC GLC GLC GLC GLC 0.610169 1
82 FUC LAT 0.610169 0.970588
83 FUC GAL GLC 0.610169 0.970588
84 BGC GAL FUC 0.610169 0.970588
85 LAT FUC 0.610169 0.970588
86 BGC GLA GAL FUC 0.609375 0.970588
87 GAL NAG GAL BGC 0.606061 0.733333
88 LAT NAG GAL 0.606061 0.733333
89 GLC GLC BGC XYS BGC XYS 0.606061 0.942857
90 BGC GAL NAG GAL 0.606061 0.733333
91 MAN GLC 0.6 1
92 LB2 0.6 1
93 M3M 0.6 1
94 SGA BGC 0.6 0.702128
95 MAL EDO 0.592593 0.942857
96 BGC BGC BGC XYS GAL 0.588235 0.942857
97 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.588235 0.942857
98 GLC GAL NAG GAL 0.588235 0.733333
99 BGC BGC BGC XYS BGC BGC 0.588235 0.942857
100 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.588235 0.942857
101 NGA GAL BGC 0.587302 0.733333
102 TRE 0.581395 1
103 ABD 0.57971 0.75
104 NDG GAL 0.578947 0.733333
105 GAL NDG 0.578947 0.733333
106 5GO 0.578947 0.66
107 NLC 0.578947 0.733333
108 DEL 0.574074 0.970588
109 GAL NGA GLA BGC GAL 0.571429 0.733333
110 MVP 0.571429 0.733333
111 GAL BGC BGC XYS 0.569231 0.942857
112 GLC GLC FRU 0.569231 0.868421
113 BMA MAN 0.566038 0.914286
114 GLC GLC XYP 0.557377 1
115 BGC BGC XYS BGC 0.552239 0.942857
116 NAG GAL BGC 0.552239 0.733333
117 GLA GAL BGC 5VQ 0.551724 0.891892
118 G2F BGC BGC BGC BGC BGC 0.55 0.868421
119 GLA MBG 0.54902 0.942857
120 GLC ACI GLD GLC 0.547945 0.785714
121 GLC G6D ACI GLC 0.547945 0.785714
122 GLC ACI G6D BGC 0.547945 0.785714
123 GLC G6D ADH GLC 0.547945 0.785714
124 GLC BGC BGC BGC 0.545455 1
125 BGC BGC BGC ASO BGC BGC ASO 0.545455 1
126 GLC BGC BGC BGC BGC BGC BGC 0.545455 1
127 BGC BGC BGC 0.545455 1
128 BGC BGC BGC GLC BGC BGC 0.545455 1
129 BGC BGC BGC BGC BGC 0.545455 1
130 MAN MAN BMA 0.535714 1
131 NGA GLA GAL BGC 0.535211 0.733333
132 BMA MAN MAN 0.534483 1
133 GAL BGC BGC BGC XYS BGC XYS 0.533333 0.942857
134 BGC BGC BGC XYS BGC XYS GAL 0.533333 0.942857
135 GLC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
136 BGC BGC BGC XYS BGC XYS XYS 0.528571 0.942857
137 BGC BGC XYS BGC XYS BGC XYS 0.528571 0.942857
138 GLA GAL GLC NBU 0.52459 0.846154
139 FUC BGC GAL 0.52459 0.970588
140 GLC ACI GLD GAL 0.519481 0.733333
141 GLC ACI G6D GLC 0.519481 0.733333
142 GLC GLC G6D ACI GLC GLC GLC 0.519481 0.785714
143 GLC BGC BGC BGC XYS BGC XYS XYS 0.513514 0.916667
144 DOM 0.509091 0.942857
145 GAL GAL SO4 0.508197 0.702128
146 DMU 0.507937 0.785714
147 LMT 0.507937 0.785714
148 LMU 0.507937 0.785714
149 G2I 0.507937 0.767442
150 G3I 0.507937 0.767442
151 OXZ BGC BGC 0.507937 0.6875
152 UMQ 0.507937 0.785714
153 GLC AGL GLC HMC 0.506329 0.717391
154 BGC BGC XYS BGC GAL XYS BGC XYS GAL 0.506329 0.942857
155 GLC BGC BGC XYS BGC XYS XYS GAL GAL 0.506329 0.942857
156 GAL BGC BGC BGC XYS XYS 0.506329 0.942857
157 GAL XYS XYS BGC BGC BGC XYS GAL BGC 0.506329 0.942857
158 GLC BGC BGC XYS BGC XYS XYS GAL 0.506329 0.942857
159 NAG GAL GAL 0.5 0.733333
160 SOR GLC GLC 0.5 0.970588
161 GAL GAL GLC EMB MEC 0.5 0.622642
162 FMO 0.5 0.868421
163 MAN BMA NAG 0.5 0.733333
164 GLA GAL NAG 0.5 0.733333
165 8VZ 0.5 0.673469
166 GLC GLC ACI G6D GLC GLC 0.493827 0.733333
167 GLC GLC AGL HMC GLC 0.493827 0.733333
168 GLC GLC DAF BGC 0.493827 0.733333
169 AAO 0.493827 0.733333
170 ARE 0.493827 0.733333
171 ACR GLC GLC GLC 0.493827 0.733333
172 GLC GLC XYS 0.492308 0.970588
173 CGC 0.491525 0.941176
174 5QP 0.491228 0.885714
175 MDM 0.490909 0.942857
176 RZM 0.490909 0.688889
177 M13 0.490909 0.942857
178 GAL MBG 0.490909 0.942857
179 GLC GLC GLC G6D ADH GLC 0.487805 0.6875
180 BGC BGC G2F SHG 0.485714 0.846154
181 MAN NAG GAL 0.485294 0.733333
182 GAL NAG MAN 0.485294 0.733333
183 6UZ 0.484848 0.846154
184 SOR GLC GLC GLC 0.484848 0.970588
185 LAG 0.484848 0.6
186 MAN MNM 0.482759 0.75
187 GAL BGC NAG GAL 0.478873 0.733333
188 10M 0.477612 0.733333
189 GTM BGC BGC 0.477612 0.868421
190 MAN MAN MAN MAN 0.476923 1
191 MAN MAN BMA MAN 0.476923 1
192 GLA GAL NAG FUC GAL GLC 0.47619 0.717391
193 NAG BMA 0.47619 0.653061
194 GAL NGA 0.47541 0.733333
195 GAL A2G 0.47541 0.733333
196 A2G GAL 0.47541 0.733333
197 BMA GLA 0.472727 1
198 LAK 0.472727 1
199 GAL GAL 0.472727 1
200 GLA GLC 0.472727 1
201 MLB 0.472727 1
202 GLA BMA 0.472727 1
203 BGC GLA 0.472727 1
204 MAN BMA 0.472727 1
205 GLA BGC 0.472727 1
206 NPJ 0.470588 0.622642
207 FUC GAL NAG GAL BGC 0.469136 0.717391
208 MAN MAN MAN GLC 0.46875 1
209 ABL 0.466667 0.702128
210 BMA FRU 0.465517 0.842105
211 FRU GAL 0.465517 0.842105
212 NOY BGC 0.465517 0.75
213 TM6 0.463768 0.916667
214 BGC SGC BGC SGC BGC SGC BGC SGC 0.463768 0.916667
215 LSE 0.462687 0.6875
216 GLA GLA FUC 0.460317 0.970588
217 FUC GAL GLA 0.460317 0.970588
218 GAL GAL FUC 0.460317 0.970588
219 GLA GAL FUC 0.460317 0.970588
220 FUC GLA GLA 0.460317 0.970588
221 DAF BGC 0.458333 0.785714
222 DAF GLC 0.458333 0.785714
223 IFM BMA 0.457627 0.744186
224 BGC OXZ 0.457627 0.666667
225 IFM BGC 0.457627 0.744186
226 BMA IFM 0.457627 0.744186
227 9MR 0.457627 0.744186
228 GLO GLC GLC 0.457143 0.942857
229 RCB 0.457143 0.622642
230 GLC GLC GLC GLC GLC BGC 0.45614 1
231 GLC GLC GLC 0.45614 1
232 GLC GLC GLC GLC BGC 0.45614 1
233 MAN MAN MAN 0.45614 1
234 GLC 0.454545 0.848485
235 BMA 0.454545 0.848485
236 GXL 0.454545 0.848485
237 WOO 0.454545 0.848485
238 GIV 0.454545 0.848485
239 GAL 0.454545 0.848485
240 MAN 0.454545 0.848485
241 BGC 0.454545 0.848485
242 ALL 0.454545 0.848485
243 GLA 0.454545 0.848485
244 GLC GLC GLC GLC 0.453125 1
245 MGL SGC GLC GLC 0.450704 0.868421
246 CM5 0.450704 0.891892
247 MAN MAN MAN BMA MAN 0.450704 1
248 BGC BGC SGC MGL 0.450704 0.868421
249 GLC DMJ 0.45 0.727273
250 A2G GAL BGC FUC 0.45 0.717391
251 GLC GLC GLC PO4 SGC GLC 0.45 0.673469
252 NOJ GLC 0.45 0.727273
253 PA1 GCS 0.448276 0.804878
254 GCS GCS 0.448276 0.804878
255 M5S 0.447761 1
256 MAN BMA MAN MAN MAN 0.447761 1
257 GLC GLC XYS XYS 0.447761 0.914286
258 DAF BGC GLC 0.447368 0.785714
259 TXT 0.447368 0.767442
260 GAC 0.447368 0.767442
261 DAF GLC GLC 0.447368 0.785714
262 ACI GLD GLC GAL 0.447368 0.785714
263 GLC GAL NAG GAL FUC FUC 0.447059 0.702128
264 BGC GAL NAG GAL FUC FUC 0.447059 0.702128
265 GAL NAG GAL NAG GAL NAG 0.445946 0.673469
266 NAG GAL GAL NAG GAL 0.445946 0.6875
267 NAG GAL GAL NAG 0.445946 0.6875
268 MA4 0.444444 0.891892
269 QV4 0.444444 0.733333
270 GLO GLC GLC GLC 0.444444 0.942857
271 MAN DGO 0.440678 0.914286
272 3SA 0.44 0.733333
273 Z6J 0.439024 0.742857
274 AHR 0.439024 0.742857
275 32O 0.439024 0.742857
276 FUB 0.439024 0.742857
277 RIB 0.439024 0.742857
278 T6P 0.438596 0.767442
279 GYP 0.4375 0.857143
280 AMG 0.4375 0.857143
281 MMA 0.4375 0.857143
282 MBG 0.4375 0.857143
283 4MU BGC BGC 0.434211 0.767442
284 ISX 0.433333 0.761905
285 MAN 7D1 0.431034 0.888889
286 QPS 0.43038 0.733333
287 ACR 0.43038 0.733333
288 4MU BGC BGC BGC BGC 0.428571 0.767442
289 GAL MGC 0.428571 0.702128
290 GAL NGA A2G 0.426471 0.673469
291 FUC NAG GAL 0.422535 0.717391
292 FUC NDG GAL 0.422535 0.717391
293 GAL NAG FUC 0.422535 0.717391
294 GAL NDG FUC 0.422535 0.717391
295 KHO 0.421053 0.888889
296 HMC AGL GLC 0.421053 0.717391
297 GCS GCS GCS GCS GCS 0.419355 0.804878
298 GCS GCS GCS GCS GCS GCS 0.419355 0.804878
299 GCS GCS GCS 0.419355 0.804878
300 GAL NAG GAL 0.418919 0.702128
301 GAL NGT 0.41791 0.66
302 P3M 0.41791 0.767442
303 NGT GAL 0.41791 0.66
304 ACR GLC GLC GLC GLC 0.417722 0.733333
305 ACR GLC 0.417722 0.733333
306 A2G GAL NAG FUC GAL GLC 0.417582 0.673469
307 GLC GAL NAG GAL FUC A2G 0.417582 0.673469
308 TUR 0.416667 0.842105
309 BTU 0.416667 0.842105
310 GLA MAN ABE 0.414286 0.916667
311 NAG NDG BMA 0.413333 0.634615
312 NAG NAG BMA 0.413333 0.634615
313 AHR AHR AHR 0.410714 0.857143
314 FUB AHR AHR 0.410714 0.857143
315 GLF B8D 0.409836 0.775
316 VAM 0.409836 0.868421
317 ACI G6D GLC ACI G6D BGC 0.409639 0.75
318 BGC GLC AC1 GLC GLC GLC AC1 0.409639 0.75
319 AC1 GLC AC1 BGC 0.409639 0.75
320 DAF GLC DAF GLC GLC 0.409639 0.75
321 ACI GLD GLC GLC GLC ACI GLD GLC GAL 0.409639 0.75
322 ACI GLD GLC ACI G6D BGC 0.409639 0.75
323 MAN MMA MAN 0.409091 0.942857
324 AHR AHR 0.407407 0.857143
325 FUB AHR 0.407407 0.857143
326 NAG BMA MAN MAN MAN MAN 0.407407 0.733333
327 G6D GLC ACI GLD GLC ACI GLD GLC BGC 0.406977 0.680851
328 4U0 0.406593 0.66
329 GLA MAN RAM ABE 0.405063 0.891892
330 BGC BGC SSG PIH 0.405063 0.767442
331 M1P 0.403846 0.697674
332 GL1 0.403846 0.697674
333 XGP 0.403846 0.697674
334 G1P 0.403846 0.697674
335 MAN IFM 0.403226 0.761905
336 GLC IFM 0.403226 0.761905
337 XZZ BGC BGC 0.402439 0.702128
338 ACG 0.402299 0.695652
339 FUC GAL 0.4 0.941176
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5T7I; Ligand: LAT NAG GAL; Similar sites found: 245
This union binding pocket(no: 1) in the query (biounit: 5t7i.bio1) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3E85 BSU 0.0007799 0.5092 None
2 5ML3 DL3 0.00144 0.4913 None
3 1VYF OLA 0.001806 0.46984 None
4 2YG2 FLC 0.003183 0.45871 None
5 2YG2 S1P 0.002567 0.45871 None
6 3ZO7 K6H 0.002244 0.44323 None
7 5BU3 4W9 0.01506 0.41756 None
8 5UR1 YY9 0.0278 0.41253 None
9 4XIZ LPP 0.03251 0.41231 None
10 5V3D FCN 0.004367 0.41066 None
11 4NJS G08 0.03648 0.40797 None
12 3M3E GAL A2G NPO 0.000001931 0.52337 1.29032
13 4RFR RHN 0.001907 0.46032 1.29032
14 5EPQ OLA 0.001648 0.45923 1.29032
15 4B7P 9UN 0.02357 0.43186 1.29032
16 4FHD 0TT 0.002834 0.46955 1.93548
17 4FHD EEM 0.002834 0.46955 1.93548
18 5DQ8 FLF 0.006223 0.44002 1.93548
19 3QRC SCR 0.0001417 0.41466 1.93548
20 5A67 3PO 0.009202 0.40961 1.93548
21 3TYZ XHP 0.02702 0.40826 1.93548
22 4XCB HY0 0.03217 0.40617 1.93548
23 1KQW RTL 0.01719 0.40789 2.23881
24 1KGI T4A 0.006943 0.4368 2.3622
25 1ZB6 GST 0.00009399 0.54587 2.58065
26 1ZB6 DIN 0.00008733 0.54587 2.58065
27 3N0Y APC 0.0002003 0.51996 2.58065
28 2XMY CDK 0.001355 0.51354 2.58065
29 3AGC RCC 0.00603 0.44432 2.58065
30 3ILR IXD 0.01737 0.43837 2.58065
31 3ILR SGN IXD 0.01911 0.43837 2.58065
32 3ILR SGN 0.01737 0.43837 2.58065
33 3MF2 AMP 0.00913 0.4299 2.58065
34 4LOO SB4 0.007952 0.42705 2.58065
35 1ODM ASV 0.01365 0.42323 2.58065
36 4QJP V1F 0.01828 0.41636 2.58065
37 1NKI PPF 0.001437 0.44868 2.96296
38 5BVB DOG 0.0009698 0.47216 3.0303
39 3RGA LSB 0.0005664 0.48252 3.22581
40 3FW9 SLX 0.002118 0.45842 3.22581
41 3FW4 CAQ 0.005202 0.44527 3.22581
42 1MEX RAC 0.008712 0.41523 3.22581
43 5E7V M7E 0.02521 0.41381 3.22581
44 5DXI TRE 0.01666 0.40977 3.22581
45 1CZI PRO PHI SMC NOR 0.02212 0.40974 3.22581
46 2DM6 NAP 0.04585 0.40921 3.22581
47 2HXT EHM 0.04347 0.40895 3.22581
48 3KFF ZBT 0.005923 0.40755 3.22581
49 3KFF XBT 0.005923 0.40755 3.22581
50 3KFC 61X 0.04504 0.40483 3.22581
51 2PVN P63 0.03619 0.40472 3.22581
52 2Q0D ATP 0.04444 0.4028 3.22581
53 4Q0L V14 0.03336 0.40218 3.22581
54 4YZC STU 0.001259 0.49224 3.87097
55 2AG4 LP3 0.003959 0.48546 3.87097
56 2AG4 OLA 0.00362 0.48546 3.87097
57 5H9Y BGC BGC BGC BGC 0.0007014 0.47439 3.87097
58 4KYS VIB 0.0008399 0.46092 3.87097
59 5IXG OTP 0.007562 0.45884 3.87097
60 4HWT 1B2 0.006352 0.43273 3.87097
61 5INJ 6C7 0.003022 0.43129 3.87097
62 5I0U DCY 0.004972 0.42935 3.87097
63 3D91 REM 0.04727 0.42353 3.87097
64 4BR5 ANP 0.02295 0.42147 3.87097
65 5DYO FLU 0.003076 0.41754 3.87097
66 2J3M PRI 0.01662 0.41751 3.87097
67 3PQB VGP 0.01535 0.41724 3.87097
68 3H22 B53 0.03001 0.41366 3.87097
69 1UMZ BGC BGC XYS BGC XYS GAL 0.00866 0.41182 3.87097
70 2DW7 SRT 0.01074 0.40857 3.87097
71 2OVW CBI 0.0115 0.40225 3.87097
72 5L2J 70E 0.01798 0.45001 4.08163
73 5L2J 6UL 0.01714 0.45001 4.08163
74 5NCF 8T5 0.002639 0.43586 4.42478
75 2P7Q GG6 0.003043 0.4344 4.51128
76 3Q8G PEE 0.002581 0.49003 4.51613
77 5U98 1KX 0.006408 0.4578 4.51613
78 4WW7 AMP 0.002653 0.45639 4.51613
79 4OMJ 2TX 0.008018 0.44551 4.51613
80 2GJ5 VD3 0.009367 0.44523 4.51613
81 2HZQ STR 0.001676 0.4421 4.51613
82 4V24 GYR 0.01225 0.43449 4.51613
83 2C49 ADN 0.006173 0.43149 4.51613
84 3B00 16A 0.001203 0.41507 4.51613
85 4MLO PAM 0.01502 0.40844 4.51613
86 1OLM VTQ 0.03192 0.40621 4.51613
87 3FW3 ETS 0.003536 0.40239 4.51613
88 5U98 VAL THR THR ASP ILE GLN VAL LYS VAL 0.048 0.40111 4.51613
89 4HIA FMN 0.01866 0.42664 4.54545
90 5FU3 BGC BGC BGC 0.001219 0.45005 4.71698
91 3TCT 3MI 0.01438 0.47546 4.72441
92 5KEW 6SB 0.003089 0.42866 4.86111
93 1Y2F WAI 0.004117 0.40195 5.03597
94 4JH6 FCN 0.001219 0.45492 5.07246
95 4MNS 2AX 0.0002816 0.54053 5.16129
96 5HA0 LTD 0.0006111 0.49668 5.16129
97 5DEY 59T 0.006278 0.45435 5.16129
98 1UU6 BGC BGC BGC BGC 0.006591 0.44264 5.16129
99 1ERB ETR 0.00643 0.44223 5.16129
100 1ZM1 BGC BGC BGC 0.004397 0.4366 5.16129
101 1GQG DCD 0.007237 0.4355 5.16129
102 1PN0 IPH 0.03158 0.42796 5.16129
103 3AMN CBK 0.01303 0.42742 5.16129
104 3AMN CBI 0.01303 0.42742 5.16129
105 2ZYI STE 0.01126 0.42577 5.16129
106 3PTQ NFG 0.007156 0.42553 5.16129
107 2OAZ I96 0.0137 0.42027 5.16129
108 4J7Q B7N 0.02643 0.41917 5.16129
109 3JRS A8S 0.01725 0.41369 5.16129
110 1VJY 460 0.02926 0.4134 5.16129
111 3KDJ A8S 0.01879 0.40918 5.16129
112 4NM5 ADP 0.02243 0.40897 5.16129
113 5H2D ERG 0.02518 0.40737 5.16129
114 3QP8 HL0 0.01891 0.40466 5.16129
115 4XBT 3ZQ 0.02472 0.40148 5.16129
116 5FP3 3JI 0.03208 0.40096 5.16129
117 1N5S ADL 0.0001404 0.42941 5.35714
118 4IPH 1FJ 0.01586 0.41937 5.69106
119 4XV1 904 0.0007434 0.50282 5.80645
120 5A3T MMK 0.00187 0.47853 5.80645
121 5F3I 5UJ 0.01326 0.45126 5.80645
122 2Y6O 1N1 0.005638 0.44011 5.80645
123 4PZV J1D 0.007889 0.43701 5.80645
124 4CQE CQE 0.02087 0.42737 5.80645
125 4H6B 10X 0.006509 0.42368 5.80645
126 4H6B 10Y 0.008259 0.4172 5.80645
127 5EQU 5R6 0.03455 0.41708 5.80645
128 4N70 2HX 0.04506 0.4164 5.80645
129 2JIG PD2 0.008476 0.41343 5.80645
130 1Z03 OCH 0.01409 0.40109 5.80645
131 5KBF CMP 0.02049 0.40089 5.80645
132 2DIO EOD 0.007421 0.42455 5.85106
133 4INI AMP 0.0173 0.40386 6.15385
134 5FPX GLY SER SER HIS HIS HIS HIS HIS 0.0003313 0.40698 6.19469
135 4H2V AMP 0.003561 0.45059 6.36364
136 3G08 FEE 0.0005289 0.53091 6.45161
137 3QUZ QUV 0.001148 0.51054 6.45161
138 3SCM LGN 0.005183 0.47677 6.45161
139 4X6F 3XU 0.004299 0.46698 6.45161
140 4K55 H6P 0.00008564 0.45682 6.45161
141 3MHA Z69 0.005555 0.44802 6.45161
142 3HXG GTA 0.003594 0.43946 6.45161
143 5HV0 AKG 0.004037 0.43778 6.45161
144 3W68 VIV 0.008661 0.4307 6.45161
145 5ITV NAI 0.02256 0.41858 6.45161
146 3B1Q NOS 0.0126 0.41804 6.45161
147 3K3K A8S 0.01329 0.41774 6.45161
148 5K8B PDG 0.01923 0.41214 6.45161
149 1TMM APC 0.03729 0.40646 6.45161
150 1TMM HHR 0.03544 0.40646 6.45161
151 1URX AAL GAL AAL GLA 0.01895 0.40283 6.45161
152 2CM4 RCL 0.01077 0.42389 6.66667
153 4P8K 38C 0.01852 0.44211 7.09677
154 4P8K FAD 0.01852 0.44211 7.09677
155 2OFV 242 0.01456 0.43426 7.09677
156 4GJ3 0XP 0.01429 0.42836 7.09677
157 4HN1 TYD 0.006174 0.42403 7.09677
158 3B6R ADP 0.01406 0.41139 7.09677
159 4ZU4 4TG 0.007984 0.42383 7.43243
160 2YAK OSV 0.004077 0.4577 7.74194
161 3SLS ANP 0.009086 0.42987 7.74194
162 4EIP FAD 0.02746 0.42779 7.74194
163 3T1A 5MA 0.008599 0.42645 7.74194
164 4WOE ADP 0.01316 0.42448 7.74194
165 3SLS 77D 0.01419 0.41411 7.74194
166 2AGC DAO 0.008438 0.41363 7.74194
167 4IAW LIZ 0.004403 0.40644 7.74194
168 4RLT FSE 0.001373 0.45907 8.16327
169 4BVM VCA 0.03127 0.40198 8.27068
170 1QY1 PRZ 0.0008156 0.48334 8.3871
171 1IIU RTL 0.002555 0.45818 8.3871
172 5ETR 5RW 0.008534 0.44571 8.3871
173 5ETR APC 0.008534 0.44571 8.3871
174 1LEK GLU GLN TYR LYS PHE TYR SER VAL 0.02792 0.43764 8.3871
175 2YNE NHW 0.03864 0.4368 8.3871
176 2YNE YNE 0.03864 0.4368 8.3871
177 1NYW DAU 0.005625 0.43651 8.3871
178 4A4X JUP 0.02829 0.40797 8.3871
179 5EYK 5U5 0.02723 0.40871 8.47458
180 3MTX PGT 0.01751 0.42688 8.60927
181 4D2S DYK 0.01663 0.40464 8.80282
182 5IXH OTP 0.01586 0.43675 9.03226
183 1KQN NAD 0.01424 0.43267 9.03226
184 5HES 032 0.009889 0.42689 9.03226
185 2YKL NLD 0.007935 0.41963 9.03226
186 5VNF VAL THR SER VAL VAL 0.009874 0.41083 9.03226
187 4WN5 MVC 0.0008615 0.48367 9.56522
188 5A65 TPP 0.001281 0.47268 9.67742
189 3THR C2F 0.007989 0.42564 9.67742
190 3LVW GSH 0.02191 0.4241 9.67742
191 5GJO PLP 0.00946 0.41701 9.67742
192 1MJJ HAL 0.0193 0.41597 9.67742
193 3AKK ADP 0.02355 0.40459 9.67742
194 1DZK PRZ 0.001198 0.40121 9.67742
195 4M1U A2G MBG 0.001342 0.41 10
196 2Z77 HE7 0.001797 0.46889 10.0719
197 2BOS GLA GAL 0.00481 0.42286 10.2941
198 5BVE 4VG 0.002875 0.49217 10.3226
199 5J75 6GQ 0.002362 0.44774 10.3226
200 4BVA T3 0.01976 0.43036 10.3226
201 3RE4 TO1 0.007546 0.42566 10.3226
202 4U0W 16G 0.0002459 0.41787 10.3226
203 4H3P ANP 0.01249 0.41662 10.3226
204 3PE2 E1B 0.04127 0.41534 10.3226
205 4P25 FUC GAL NAG FUC 0.01932 0.40596 10.3226
206 4H2W 5GP 0.002461 0.45329 10.6796
207 4H2W AMP 0.002314 0.45232 10.6796
208 2VFT SOR 0.001128 0.4237 10.9677
209 5FXD H7Y 0.008817 0.42292 10.9677
210 4ZSI 4R1 0.0001511 0.51279 11.6129
211 4ZSI GLP 0.0002989 0.49593 11.6129
212 3QCQ 3Q0 0.01891 0.45523 11.6129
213 3VRV YSD 0.03647 0.4208 11.6129
214 2HRL SIA GAL SIA BGC NGA CEQ 0.003022 0.43561 11.811
215 3VQ2 LP4 LP5 MYR DAO 0.001048 0.50505 12.2581
216 5FBN 5WF 0.009393 0.44304 12.2581
217 1J3R 6PG 0.004766 0.42751 12.2581
218 1GP6 QUE 0.01246 0.42717 12.2581
219 1GP6 SIN 0.01291 0.42499 12.2581
220 1GP6 DH2 0.01291 0.42499 12.2581
221 5EYP GTP 0.03577 0.40466 12.2581
222 5BYZ 4WE 0.003337 0.46218 12.9032
223 3T4L ZEA 0.0228 0.40383 12.9032
224 2A1L PCW 0.0005607 0.52063 13.5484
225 4PFC 2QX 0.01767 0.41988 13.5484
226 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 0.02793 0.41668 13.5484
227 3FON VAL ASN ASP ILE PHE GLU ALA ILE 0.01171 0.43376 14.1935
228 2I74 MAN MAN MAN MAN 0.004602 0.42149 14.1935
229 1U6R ADP 0.02412 0.40038 14.1935
230 4F7E 0SH 0.007346 0.45356 14.2857
231 3L9R L9R 0.01083 0.44283 14.2857
232 3L9R L9Q 0.02618 0.41895 14.2857
233 1DY4 SNP 0.01979 0.44351 16.129
234 3AJH BL3 0.008854 0.42016 16.129
235 1U0A BGC BGC BGC BGC 0.0001814 0.50738 16.7742
236 2RDE C2E 0.01799 0.40205 16.7742
237 4NFN 2KC 0.003251 0.44502 17.4194
238 4BTK DTQ 0.02326 0.40288 17.4194
239 2PYW ADP 0.01961 0.41019 19.3548
240 1TT8 PHB 0.002799 0.46239 20
241 4QA8 PJZ 0.0002885 0.50991 21.2903
242 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 0.01383 0.43014 22.5806
243 3PUR 2HG 0.008593 0.40907 23.871
244 3VV1 GAL FUC 0.000000006336 0.62233 32.9032
245 1QKQ MAN 0.00000002446 0.73028 49.2958
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