Receptor
PDB id Resolution Class Description Source Keywords
4BLW 1.95 Å EC: 2.1.1.266 CRYSTAL STRUCTURE OF ESCHERICHIA COLI 23S RRNA (A2030-N6)- METHYLTRANSFERASE RLMJ IN COMPLEX WITH S-ADENOSYLHOMOCYSTEI( ADOHCY) AND ADENOSINE MONOPHOSPHATE (AMP) ESCHERICHIA COLI TRANSFERASE N6-METHYLADENINE ROSSMANN-LIKE FOLD SUBDOMAININSERTION
Ref.: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THE MOLECUL MECHANISM OF RRNA M6A METHYLTRANSFERASE RLMJ. NUCLEIC ACIDS RES. V. 41 9537 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO B:1283;
A:1289;
A:1286;
B:1285;
B:1284;
A:1285;
A:1291;
A:1287;
A:1292;
B:1288;
B:1286;
A:1293;
A:1290;
A:1288;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
NA A:1294;
B:1287;
Part of Protein;
Part of Protein;
none;
none;
submit data
22.99 Na [Na+]
SAH A:1282;
B:1281;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
GOL B:1282;
A:1284;
A:1283;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SO4 A:1295;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
AMP A:1281;
B:1280;
Valid;
Valid;
none;
none;
submit data
347.221 C10 H14 N5 O7 P c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6QE5 1.61 Å EC: 2.1.1.266 STRUCTURE OF E.COLI RLMJ IN COMPLEX WITH THE NATURAL COFACTO S-ADENOSYL-HOMOCYSTEINE (SAH) ESCHERICHIA COLI PCN033 RNA MTASES METHYLTRANSFERASE M6A TRANSITION STATE ANALOGUINHIBITOR RNA BINDING TRMK RLMJ M1A STRUCTURE. TRANSF
Ref.: BISUBSTRATE ANALOGUES AS STRUCTURAL TOOLS TO INVEST METHYLTRANSFERASE ACTIVE SITES. RNA BIOL. V. 16 798 2019
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4BLW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 6QDX Kd = 30 uM HY8 C27 H38 N12 O9 c1nc(c2c(n....
3 6QE0 Kd = 25 uM HZ2 C26 H36 N12 O9 c1nc(c2c(n....
4 4BLV - SAM C15 H22 N6 O5 S C[S@@+](CC....
5 6QE5 Kd = 7.5 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4BLW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 6QDX Kd = 30 uM HY8 C27 H38 N12 O9 c1nc(c2c(n....
3 6QE0 Kd = 25 uM HZ2 C26 H36 N12 O9 c1nc(c2c(n....
4 4BLV - SAM C15 H22 N6 O5 S C[S@@+](CC....
5 6QE5 Kd = 7.5 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4BLW - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 6QDX Kd = 30 uM HY8 C27 H38 N12 O9 c1nc(c2c(n....
3 6QE0 Kd = 25 uM HZ2 C26 H36 N12 O9 c1nc(c2c(n....
4 4BLV - SAM C15 H22 N6 O5 S C[S@@+](CC....
5 6QE5 Kd = 7.5 uM SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 231
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 RAB 0.573333 0.84058
19 XYA 0.573333 0.84058
20 ADN 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SSA 0.536842 0.712644
28 SMM 0.536842 0.88
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 OZP 0.518519 0.915493
44 AAT 0.515789 0.863014
45 LSS 0.515152 0.696629
46 KAA 0.514852 0.727273
47 J7C 0.511364 0.835616
48 KG4 0.51087 0.769231
49 A5A 0.510417 0.697674
50 SON 0.505495 0.805195
51 SRP 0.505155 0.805195
52 F0P 0.504505 0.915493
53 ADX 0.5 0.694118
54 5AL 0.5 0.779221
55 54H 0.5 0.681818
56 VMS 0.5 0.681818
57 KH3 0.5 0.866667
58 HY8 0.5 0.890411
59 AMO 0.5 0.805195
60 CA0 0.5 0.769231
61 N37 0.495495 0.9
62 HZ2 0.495413 0.890411
63 AHX 0.49505 0.753086
64 NVA LMS 0.49505 0.707865
65 TSB 0.494949 0.689655
66 53H 0.494949 0.674157
67 G5A 0.494737 0.712644
68 ABM 0.494382 0.74359
69 A2D 0.494382 0.74359
70 45A 0.494382 0.74359
71 ZAS 0.494253 0.808219
72 A6D 0.490196 0.759494
73 GEK 0.49 0.956522
74 8QN 0.49 0.779221
75 GAP 0.489583 0.769231
76 A3S 0.48913 0.884058
77 AN2 0.48913 0.734177
78 S4M 0.488889 0.831169
79 SRA 0.488636 0.746835
80 LAD 0.485437 0.810127
81 52H 0.484848 0.674157
82 AP2 0.483516 0.759494
83 A12 0.483516 0.759494
84 BA3 0.483516 0.74359
85 NEC 0.483146 0.788732
86 AOC 0.483146 0.842857
87 Y3J 0.481481 0.768116
88 VRT 0.479167 0.861111
89 50T 0.478723 0.734177
90 5AS 0.478261 0.655556
91 ADP 0.478261 0.74359
92 AP5 0.478261 0.74359
93 B4P 0.478261 0.74359
94 A3N 0.477778 0.830986
95 YSA 0.476636 0.712644
96 XAH 0.476636 0.768293
97 8LH 0.474747 0.759494
98 0XU 0.473684 0.897059
99 AT4 0.473118 0.7375
100 ADP MG 0.473118 0.763158
101 J4G 0.471154 0.818182
102 WAQ 0.471154 0.807692
103 NSS 0.470588 0.712644
104 8LE 0.469388 0.75
105 5AD 0.468354 0.791045
106 M33 0.468085 0.734177
107 AU1 0.468085 0.725
108 MAO 0.467391 0.797468
109 NB8 0.466667 0.775
110 A3G 0.466667 0.871429
111 TXA 0.466667 0.759494
112 N5O 0.466667 0.857143
113 3AM 0.465909 0.727273
114 8X1 0.465347 0.707865
115 8LQ 0.465347 0.782051
116 DAL AMP 0.465347 0.779221
117 ACP 0.463158 0.746835
118 ATP 0.463158 0.74359
119 A3T 0.463158 0.842857
120 HEJ 0.463158 0.74359
121 7D7 0.4625 0.785714
122 LEU LMS 0.461538 0.688889
123 9ZD 0.460784 0.740741
124 9ZA 0.460784 0.740741
125 APR 0.458333 0.766234
126 AQP 0.458333 0.74359
127 APC 0.458333 0.759494
128 AR6 0.458333 0.766234
129 PRX 0.458333 0.746835
130 5FA 0.458333 0.74359
131 F2R 0.457627 0.75
132 IOT 0.456897 0.761905
133 N5A 0.456522 0.855072
134 4AD 0.456311 0.794872
135 PAJ 0.456311 0.722892
136 WSA 0.45614 0.72093
137 HQG 0.455446 0.75641
138 FA5 0.453704 0.805195
139 8PZ 0.453704 0.712644
140 YAP 0.453704 0.794872
141 NVA 2AD 0.453608 0.849315
142 ATP MG 0.453608 0.763158
143 AD9 0.453608 0.725
144 SAP 0.453608 0.728395
145 AGS 0.453608 0.728395
146 ADP PO3 0.453608 0.763158
147 APC MG 0.453608 0.766234
148 ADV 0.453608 0.782051
149 RBY 0.453608 0.782051
150 PTJ 0.45283 0.731707
151 MHZ 0.452632 0.797468
152 00A 0.451923 0.740741
153 A3P 0.451613 0.74026
154 YLP 0.451327 0.771084
155 7MD 0.45045 0.768293
156 ALF ADP 0.45 0.707317
157 ADP ALF 0.45 0.707317
158 2VA 0.447917 0.819444
159 H1Q 0.447917 0.753247
160 OOB 0.446602 0.779221
161 ANP 0.444444 0.725
162 ACQ 0.444444 0.746835
163 TAT 0.444444 0.7375
164 T99 0.444444 0.7375
165 P5A 0.443396 0.719101
166 7D5 0.443182 0.708861
167 A1R 0.442308 0.7625
168 YLC 0.439655 0.790123
169 2AM 0.438202 0.717949
170 DLL 0.438095 0.779221
171 ARG AMP 0.4375 0.759036
172 A22 0.436893 0.734177
173 D3Y 0.436893 0.859155
174 ATF 0.435644 0.716049
175 MYR AMP 0.435185 0.746988
176 80F 0.434426 0.75
177 SO8 0.434343 0.808219
178 3UK 0.433962 0.769231
179 OAD 0.433962 0.769231
180 TAD 0.433628 0.765432
181 25A 0.432692 0.74359
182 ADP VO4 0.431373 0.734177
183 VO4 ADP 0.431373 0.734177
184 6YZ 0.431373 0.746835
185 9SN 0.431193 0.731707
186 TYM 0.431034 0.805195
187 PR8 0.429907 0.8
188 B5V 0.429907 0.759494
189 ADQ 0.428571 0.746835
190 YLB 0.42735 0.771084
191 FYA 0.425926 0.779221
192 9K8 0.425926 0.67033
193 1ZZ 0.425926 0.746988
194 3OD 0.425926 0.769231
195 PPS 0.425743 0.674419
196 B1U 0.423423 0.638298
197 MAP 0.423077 0.707317
198 4YB 0.421053 0.735632
199 A2P 0.421053 0.727273
200 ADP BMA 0.420561 0.746835
201 9X8 0.420561 0.75
202 TYR AMP 0.419643 0.794872
203 5SV 0.419048 0.731707
204 OZV 0.419048 0.74359
205 3NZ 0.416667 0.824324
206 YLA 0.416667 0.771084
207 8Q2 0.415254 0.688889
208 A3R 0.415094 0.7625
209 B5M 0.414414 0.75
210 B5Y 0.414414 0.75
211 LPA AMP 0.413793 0.768293
212 48N 0.413793 0.753086
213 AYB 0.413223 0.761905
214 ACK 0.413043 0.710526
215 QQY 0.413043 0.696203
216 BIS 0.412844 0.719512
217 JB6 0.412844 0.7625
218 PAP 0.41 0.730769
219 DQV 0.408696 0.75641
220 OVE 0.408602 0.7125
221 AMP DBH 0.40708 0.746835
222 4UV 0.40708 0.75
223 3AD 0.406977 0.852941
224 OMR 0.40678 0.738095
225 AF3 ADP 3PG 0.40678 0.743902
226 LAQ 0.405172 0.768293
227 A A 0.40367 0.74359
228 7C5 0.403509 0.789474
229 7MC 0.403361 0.75
230 KOY 0.401709 0.847222
231 4UU 0.4 0.75
Ligand no: 2; Ligand: AMP; Similar ligands found: 422
No: Ligand ECFP6 Tc MDL keys Tc
1 AMP 1 1
2 A 1 1
3 45A 0.833333 0.943662
4 ABM 0.833333 0.943662
5 A2D 0.833333 0.943662
6 ADP 0.823529 0.971429
7 AP2 0.808824 0.931507
8 BA3 0.808824 0.943662
9 A12 0.808824 0.931507
10 SRA 0.80303 0.944444
11 AP5 0.797101 0.943662
12 B4P 0.797101 0.943662
13 HEJ 0.788732 0.971429
14 ATP 0.788732 0.971429
15 AT4 0.785714 0.931507
16 AN2 0.785714 0.957747
17 APC 0.777778 0.931507
18 AQP 0.777778 0.971429
19 5FA 0.777778 0.971429
20 AU1 0.774648 0.944444
21 CA0 0.774648 0.917808
22 M33 0.774648 0.930556
23 ADX 0.774648 0.848101
24 50T 0.763889 0.957747
25 KG4 0.763889 0.917808
26 ACP 0.763889 0.944444
27 ADP MG 0.760563 0.942857
28 25A 0.75641 0.971429
29 APR 0.753425 0.943662
30 AR6 0.753425 0.943662
31 PRX 0.753425 0.917808
32 ACQ 0.746667 0.944444
33 TAT 0.746667 0.931507
34 T99 0.746667 0.931507
35 ADV 0.743243 0.905405
36 SAP 0.743243 0.918919
37 AGS 0.743243 0.918919
38 AD9 0.743243 0.944444
39 RBY 0.743243 0.905405
40 ANP 0.723684 0.944444
41 ATP MG 0.72 0.942857
42 APC MG 0.72 0.916667
43 ADP PO3 0.72 0.942857
44 6YZ 0.717949 0.944444
45 8LE 0.714286 0.893333
46 5AL 0.714286 0.930556
47 SON 0.712329 0.931507
48 LMS 0.710145 0.825
49 RAB 0.709677 0.842857
50 ADN 0.709677 0.842857
51 XYA 0.709677 0.842857
52 HQG 0.708861 0.957747
53 ATF 0.705128 0.931507
54 GAP 0.701299 0.891892
55 A22 0.7 0.957747
56 SRP 0.696203 0.905405
57 8LH 0.696203 0.905405
58 7D5 0.691176 0.902778
59 A3P 0.684932 0.971014
60 A2P 0.684932 0.956522
61 ALF ADP 0.683544 0.868421
62 ADP ALF 0.683544 0.868421
63 ADQ 0.682927 0.917808
64 8LQ 0.679012 0.905405
65 MAP 0.679012 0.918919
66 VO4 ADP 0.675 0.930556
67 ADP VO4 0.675 0.930556
68 8QN 0.670732 0.930556
69 5SV 0.670732 0.87013
70 OOB 0.670732 0.930556
71 9ZD 0.670732 0.906667
72 9ZA 0.670732 0.906667
73 OZV 0.670732 0.943662
74 PTJ 0.670588 0.894737
75 AOC 0.666667 0.84507
76 AMO 0.662651 0.905405
77 4AD 0.662651 0.893333
78 A3R 0.662651 0.881579
79 A1R 0.662651 0.881579
80 PAJ 0.662651 0.858974
81 5N5 0.661538 0.816901
82 DAL AMP 0.658537 0.90411
83 IMO 0.657534 0.928571
84 DLL 0.654762 0.930556
85 AHX 0.654762 0.87013
86 00A 0.654762 0.881579
87 5AS 0.653333 0.776471
88 5CD 0.651515 0.828571
89 A4D 0.651515 0.816901
90 6MZ 0.648649 0.957143
91 9X8 0.647059 0.893333
92 3UK 0.647059 0.917808
93 OAD 0.647059 0.917808
94 ADP BMA 0.647059 0.891892
95 25L 0.643678 0.957747
96 B5V 0.639535 0.905405
97 WAQ 0.639535 0.881579
98 LAD 0.639535 0.858974
99 PR8 0.639535 0.848101
100 DTA 0.637681 0.808219
101 V3L 0.6375 0.971429
102 3DH 0.633803 0.794521
103 1ZZ 0.632184 0.8375
104 NB8 0.632184 0.87013
105 TXA 0.632184 0.905405
106 FYA 0.632184 0.930556
107 BIS 0.632184 0.906667
108 ME8 0.632184 0.8375
109 3OD 0.632184 0.917808
110 MTA 0.628571 0.794521
111 3AM 0.625 0.956522
112 EP4 0.623188 0.773333
113 A A 0.62069 0.971429
114 9SN 0.617977 0.87013
115 M2T 0.614286 0.753247
116 JB6 0.613636 0.881579
117 FA5 0.611111 0.905405
118 B5Y 0.611111 0.893333
119 YAP 0.611111 0.893333
120 B5M 0.611111 0.893333
121 H1Q 0.607595 0.929577
122 MYR AMP 0.606742 0.814815
123 G5A 0.604938 0.776471
124 XAH 0.604396 0.8375
125 4UV 0.597826 0.893333
126 71V 0.597403 0.906667
127 ATP A 0.593407 0.929577
128 ATP A A A 0.593407 0.929577
129 PAP 0.592593 0.957143
130 G3A 0.591398 0.894737
131 2AM 0.589041 0.942857
132 5X8 0.5875 0.783784
133 6RE 0.586667 0.779221
134 6C6 0.585366 0.905405
135 G5P 0.585106 0.894737
136 4UU 0.585106 0.893333
137 GA7 0.585106 0.905405
138 AFH 0.585106 0.858974
139 7D3 0.584416 0.878378
140 A5A 0.583333 0.804878
141 TSB 0.581395 0.795181
142 TYR AMP 0.580645 0.868421
143 AMP DBH 0.580645 0.891892
144 2A5 0.580247 0.891892
145 GTA 0.578947 0.860759
146 TAD 0.578947 0.858974
147 DQV 0.578947 0.930556
148 DSH 0.578947 0.74359
149 6IA 0.578313 0.858974
150 SSA 0.576471 0.776471
151 C2R 0.575342 0.876712
152 AMZ 0.575342 0.888889
153 7D4 0.575 0.878378
154 PGS 0.575 0.857143
155 ZAS 0.573333 0.786667
156 ATR 0.573171 0.942857
157 LAQ 0.572917 0.8375
158 J7C 0.571429 0.789474
159 AIR 0.571429 0.927536
160 A3N 0.571429 0.783784
161 AAM 0.571429 1
162 PPS 0.571429 0.848101
163 54H 0.569767 0.785714
164 52H 0.569767 0.776471
165 VMS 0.569767 0.785714
166 AR6 AR6 0.568421 0.916667
167 7MD 0.568421 0.8375
168 ARG AMP 0.568421 0.82716
169 48N 0.56701 0.87013
170 YLP 0.56701 0.817073
171 OVE 0.565789 0.90411
172 UPA 0.565657 0.881579
173 2SA 0.564706 0.905405
174 S4M 0.564103 0.682353
175 8X1 0.563218 0.75
176 5CA 0.563218 0.776471
177 53H 0.563218 0.776471
178 TXD 0.561224 0.881579
179 DND 0.561224 0.905405
180 NAI 0.561224 0.881579
181 UP5 0.561224 0.893333
182 NXX 0.561224 0.905405
183 NAX 0.561224 0.848101
184 4UW 0.561224 0.858974
185 6V0 0.561224 0.87013
186 NIA 0.56 0.820513
187 DA 0.558442 0.902778
188 D5M 0.558442 0.902778
189 MAO 0.556962 0.777778
190 AHZ 0.556701 0.814815
191 TXE 0.555556 0.881579
192 OMR 0.555556 0.82716
193 TYM 0.555556 0.905405
194 ITT 0.555556 0.915493
195 5AD 0.552239 0.768116
196 A2R 0.551724 0.957747
197 LPA AMP 0.55102 0.814815
198 NSS 0.550562 0.776471
199 DSZ 0.550562 0.776471
200 LSS 0.550562 0.758621
201 YLB 0.55 0.817073
202 YLC 0.55 0.8375
203 4TC 0.55 0.87013
204 AP0 0.55 0.87013
205 P5A 0.549451 0.741573
206 J4G 0.549451 0.918919
207 139 0.54902 0.848101
208 A4P 0.544554 0.819277
209 NVA LMS 0.544444 0.75
210 GJV 0.544304 0.769231
211 7D7 0.544118 0.763889
212 9K8 0.543478 0.711111
213 A7D 0.54321 0.797297
214 AF3 ADP 3PG 0.54 0.835443
215 6K6 0.539326 0.957143
216 IOT 0.539216 0.829268
217 LEU LMS 0.538462 0.75
218 A3G 0.538462 0.797297
219 A5D 0.535714 0.808219
220 7MC 0.534653 0.817073
221 YLA 0.533981 0.817073
222 T5A 0.533981 0.817073
223 ADJ 0.533981 0.82716
224 KAA 0.532609 0.75
225 GSU 0.532609 0.776471
226 7RA 0.531646 0.985507
227 SFG 0.53012 0.77027
228 HFD 0.529412 0.918919
229 JSQ 0.529412 0.918919
230 SAH 0.529412 0.763158
231 AYB 0.528846 0.807229
232 CNA 0.528846 0.905405
233 N6P 0.527473 0.942029
234 8BR 0.525 0.931507
235 F2R 0.52381 0.839506
236 80F 0.523364 0.817073
237 Y3J 0.521127 0.746479
238 YSA 0.520833 0.776471
239 7RP 0.518987 0.955882
240 NAD 0.518868 0.930556
241 G A A A 0.518868 0.87013
242 COD 0.518868 0.788235
243 BTX 0.518868 0.839506
244 MHZ 0.518072 0.714286
245 SA8 0.517647 0.725
246 6AD 0.517241 0.883117
247 BT5 0.514019 0.829268
248 DZD 0.514019 0.858974
249 RMB 0.5125 0.898551
250 SAI 0.511628 0.753247
251 AV2 0.511364 0.890411
252 8PZ 0.510417 0.776471
253 A3D 0.509259 0.917808
254 A3S 0.506024 0.808219
255 3AT 0.505747 0.943662
256 SAM 0.505747 0.707317
257 SMM 0.505618 0.702381
258 NA7 0.505376 0.931507
259 B1U 0.505155 0.733333
260 AMP NAD 0.504673 0.90411
261 4TA 0.504673 0.804878
262 NO7 0.5 0.905405
263 G 0.5 0.905405
264 5GP 0.5 0.905405
265 NEC 0.5 0.743243
266 EEM 0.5 0.707317
267 AAT 0.5 0.725
268 M24 0.495495 0.848101
269 YLY 0.495495 0.807229
270 7C5 0.494949 0.815789
271 DAT 0.494118 0.878378
272 A3T 0.494118 0.819444
273 FAI 0.493827 0.888889
274 P2P 0.493827 0.928571
275 1RB 0.493671 0.911765
276 NAE 0.491071 0.893333
277 NAJ PZO 0.490909 0.846154
278 U A 0.490909 0.906667
279 A G 0.490741 0.881579
280 KOY 0.490196 0.8
281 LQJ 0.489796 0.916667
282 TM1 0.489583 0.771084
283 A A A 0.489362 0.90411
284 A6D 0.489362 0.740741
285 PO4 PO4 A A A A PO4 0.489362 0.901408
286 S7M 0.488889 0.707317
287 DTP 0.488636 0.878378
288 RBZ 0.4875 0.873239
289 101 0.4875 0.902778
290 EAD 0.486957 0.848101
291 NAQ 0.486726 0.87013
292 U A G G 0.486239 0.881579
293 4YB 0.485149 0.758621
294 NDE 0.483051 0.931507
295 ZID 0.482456 0.917808
296 N0B 0.482456 0.817073
297 N5O 0.481481 0.76
298 WSA 0.480769 0.785714
299 RGT 0.479592 0.931507
300 ARU 0.478723 0.835443
301 GGZ 0.478261 0.8
302 JLN 0.47561 0.863014
303 ANZ 0.475248 0.820513
304 ACK 0.475 0.885714
305 QQY 0.475 0.837838
306 NAJ PYZ 0.473684 0.804878
307 GEK 0.473118 0.734177
308 AVV 0.473118 0.87013
309 S8M 0.473118 0.779221
310 3AD 0.472973 0.828571
311 A U 0.471698 0.868421
312 P1H 0.470588 0.82716
313 N5A 0.46988 0.733333
314 0UM 0.468085 0.716049
315 RVP 0.467532 0.847222
316 649 0.466667 0.741573
317 Z5A 0.465517 0.776471
318 PMO 0.464286 0.873239
319 SXZ 0.463918 0.707317
320 62X 0.463158 0.682353
321 QQX 0.4625 0.826667
322 8Q2 0.462264 0.75
323 2VA 0.45977 0.797297
324 IMP 0.458824 0.90411
325 CC5 0.458333 0.84058
326 K15 0.458333 0.698795
327 AS 0.457831 0.855263
328 DDS 0.455556 0.851351
329 V1N 0.455446 0.943662
330 NJP 0.454545 0.918919
331 7DD 0.453488 0.957143
332 G7M 0.453488 0.87013
333 93A 0.453488 0.804878
334 3D1 0.453333 0.77027
335 3L1 0.453333 0.77027
336 EO7 0.452381 0.785714
337 NDC 0.45082 0.87013
338 FB0 0.45082 0.781609
339 0WD 0.45045 0.894737
340 NVA 2AD 0.449438 0.75641
341 2FA 0.447368 0.810811
342 26A 0.447368 0.76
343 CMP 0.447059 0.927536
344 2BA 0.447059 0.914286
345 D3Y 0.446809 0.786667
346 VRT 0.444444 0.766234
347 APU 0.444444 0.893333
348 KB1 0.444444 0.716049
349 SO8 0.444444 0.786667
350 FDA 0.443548 0.809524
351 PUA 0.443478 0.858974
352 ODP 0.441441 0.883117
353 6FA 0.44 0.817073
354 103 0.439024 0.861111
355 RP1 0.439024 0.864865
356 SP1 0.439024 0.864865
357 3NZ 0.438776 0.779221
358 A C A C 0.438596 0.846154
359 7DT 0.438202 0.957143
360 NDP 0.436364 0.894737
361 NPW 0.436364 0.860759
362 MTP 0.434211 0.727273
363 FAD 0.433071 0.82716
364 SFD 0.433071 0.712766
365 FAS 0.433071 0.82716
366 ZZB 0.432432 0.792683
367 NZQ 0.432432 0.883117
368 IRN 0.432432 0.867647
369 TXP 0.432432 0.894737
370 62F 0.430769 0.8375
371 FNK 0.430769 0.781609
372 128 0.429907 0.752941
373 PAX 0.428571 0.82716
374 6MD 0.428571 0.805556
375 1DA 0.428571 0.842857
376 9BG 0.428571 0.87013
377 SLU 0.426087 0.767442
378 XNP 0.424779 0.848101
379 HZ2 0.424528 0.728395
380 12D 0.424528 0.761905
381 5F1 0.423077 0.72973
382 ETB 0.422414 0.809524
383 DCA 0.422414 0.8
384 F0P 0.422018 0.725
385 ERJ 0.421687 0.777778
386 GUO 0.421053 0.864865
387 WMP 0.421053 0.864865
388 OZP 0.420561 0.725
389 FAY 0.416667 0.8375
390 HY8 0.416667 0.728395
391 38Y 0.415929 0.804878
392 5J9 0.415842 0.728395
393 0T1 0.415254 0.8
394 COA 0.415254 0.8
395 KH3 0.415094 0.690476
396 N01 0.413793 0.90411
397 FMP 0.413793 0.871429
398 U A C C 0.413793 0.857143
399 RFL 0.413534 0.797619
400 NMN AMP PO4 0.412281 0.868421
401 GP2 0.408602 0.858974
402 GDP 0.408602 0.893333
403 NAP 0.408333 0.944444
404 NOC 0.407895 0.760563
405 2ER 0.405941 0.831169
406 1PR 0.405941 0.820513
407 P5F 0.405797 0.8
408 30N 0.404959 0.731183
409 CAO 0.404959 0.772727
410 COS 0.404959 0.781609
411 AMX 0.404959 0.809524
412 TAP 0.404959 0.906667
413 XMP 0.402299 0.891892
414 G2P 0.402062 0.858974
415 APC G U 0.401709 0.833333
416 CMX 0.401639 0.8
417 SCO 0.401639 0.8
418 U A A U 0.401639 0.906667
419 NA0 0.401639 0.931507
420 9JJ 0.40146 0.8375
421 F2N 0.4 0.790698
422 N37 0.4 0.730769
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6QE5; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6qe5.bio2) has 38 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 6QE5; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6qe5.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
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