Receptor
PDB id Resolution Class Description Source Keywords
4BFM 2.35 Å EC: 2.7.11.1 THE CRYSTAL STRUCTURE OF MOUSE PK38 MUS MUSCULUS TRANSFERASE
Ref.: THE STRUCTURES OF THE KINASE DOMAIN AND UBA DOMAIN SUGGEST THE ACTIVATION MECHANISM FOR KINASE ACTIVIT ACTA CRYSTALLOGR.,SECT.D V. 70 514 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 A:2006;
A:2001;
A:2004;
A:2003;
A:2002;
A:2007;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
ANP A:1000;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4BFM 2.35 Å EC: 2.7.11.1 THE CRYSTAL STRUCTURE OF MOUSE PK38 MUS MUSCULUS TRANSFERASE
Ref.: THE STRUCTURES OF THE KINASE DOMAIN AND UBA DOMAIN SUGGEST THE ACTIVATION MECHANISM FOR KINASE ACTIVIT ACTA CRYSTALLOGR.,SECT.D V. 70 514 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 4BFM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 4BFM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 5IH8 ic50 = 0.18 uM 6BJ C21 H17 N5 O c1ccnc(c1)....
3 5IH9 ic50 = 0.002 uM 6BF C25 H32 N6 O CN1CCN(CC1....
4 5IHA ic50 = 0.41 uM 6BE C23 H29 N5 O CC(C)COc1c....
5 4BKZ ic50 = 0.027 uM 1WS C18 H20 F N7 O c1cc(cc(c1....
6 4BKY ic50 = 0.012 uM 82B C26 H30 Br N7 O2 Cn1cc(cc1C....
7 5K00 ic50 = 7.1 nM 6PV C32 H34 N6 O4 COc1cccc(c....
8 5IHC ic50 = 0.013 uM 6BB C20 H21 F N4 O c1ccc(c(c1....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 4BFM - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 5IH8 ic50 = 0.18 uM 6BJ C21 H17 N5 O c1ccnc(c1)....
3 5IH9 ic50 = 0.002 uM 6BF C25 H32 N6 O CN1CCN(CC1....
4 5IHA ic50 = 0.41 uM 6BE C23 H29 N5 O CC(C)COc1c....
5 4BKZ ic50 = 0.027 uM 1WS C18 H20 F N7 O c1cc(cc(c1....
6 4BKY ic50 = 0.012 uM 82B C26 H30 Br N7 O2 Cn1cc(cc1C....
7 5K00 ic50 = 7.1 nM 6PV C32 H34 N6 O4 COc1cccc(c....
8 5IHC ic50 = 0.013 uM 6BB C20 H21 F N4 O c1ccc(c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4BFM; Ligand: ANP; Similar sites found: 336
This union binding pocket(no: 1) in the query (biounit: 4bfm.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4XMF HSM 0.00005929 0.55539 None
2 4PU5 ANP 0.001674 0.41372 1.1976
3 3ETH ATP 0.001146 0.43401 1.49701
4 2Z48 NGA 0.00971 0.43038 1.49701
5 2Z49 AMG 0.009644 0.41286 1.49701
6 3TII ANP 0.0007042 0.4126 1.49701
7 1ZB6 DIN 0.0062 0.41213 1.62866
8 1ZB6 GST 0.006693 0.41203 1.62866
9 5FS0 5JC 0.002426 0.4487 1.89573
10 3BU1 HSM 0.0157 0.41055 2.02703
11 3PDT ADP 0.0000002062 0.62214 2.09581
12 1PK8 ATP 0.00008242 0.45429 2.09581
13 3K5I ADP 0.001199 0.43119 2.09581
14 3NOJ PYR 0.01295 0.43148 2.10084
15 3VPC ADP 0.00006749 0.47627 2.12766
16 1AUX AGS 0.000126 0.48251 2.2508
17 2CFM AMP 0.003384 0.43656 2.39521
18 5TDF ADP 0.0008209 0.43814 2.46914
19 2VQD AP2 0.0002388 0.46082 2.69461
20 1M0W ANP 0.0005461 0.42248 2.69461
21 4MV1 ADP 0.005429 0.41867 2.69461
22 2Q7D ANP 0.008385 0.40352 2.69461
23 1H82 FAD 0.03532 0.40174 2.69461
24 1H82 GZZ 0.04092 0.40174 2.69461
25 4FE2 ADP 0.0009466 0.45808 2.7451
26 4MYD 164 0.01788 0.40543 2.77778
27 4D4U FUC NDG GAL FUC 0.005133 0.43647 2.85714
28 4D4U FUC GAL NAG 0.02107 0.40734 2.85714
29 1IOW PHY 0.00109 0.45241 2.94118
30 1IOW ADP 0.00109 0.45241 2.94118
31 3X01 AMP 0.0002023 0.51325 2.99401
32 2VPQ ANP 0.00006536 0.48912 2.99401
33 3W0O ADP 0.00002994 0.44454 2.99401
34 3W0O HY0 0.00002994 0.44454 2.99401
35 1T36 ADP 0.006177 0.41078 2.99401
36 1W2D ADP 0.00005191 0.52448 3.01887
37 1W2D 4IP 0.0005757 0.40511 3.01887
38 1GSA ADP 0.000005882 0.53387 3.16456
39 1IA9 ANP 0.0000004811 0.58184 3.21429
40 1YRO UDP 0.009466 0.41643 3.25203
41 2PYW ADP 0.000001811 0.55046 3.29341
42 3I0O ADP 0.00003838 0.53083 3.29341
43 5VZ0 ADP 0.0001152 0.45833 3.29341
44 2OVD DAO 0.01527 0.41635 3.2967
45 1KDK DHT 0.002984 0.40401 3.38983
46 4ZGP ADP 0.003175 0.40043 3.41297
47 3KA2 2NC 0.005443 0.43598 3.44828
48 2AQX ATP 0.000178 0.46841 3.46021
49 3UDZ ADP 0.00000002712 0.61864 3.59281
50 5MW8 ATP 0.00000006255 0.61829 3.59281
51 5I35 ANP 0.0000001725 0.56932 3.59281
52 2PUL ACP 0.000002219 0.56702 3.59281
53 4AXD ANP 0.00000005193 0.48529 3.59281
54 4ME6 ADP 0.01035 0.42288 3.59281
55 5ABF XRJ 0.008468 0.40534 3.59281
56 2CHN NGT 0.01028 0.40516 3.59281
57 5ABH YWN 0.004411 0.40203 3.59281
58 4GYI ADP 0.000005951 0.56216 3.89222
59 2HGS ADP 0.0002995 0.46084 3.89222
60 4OYA 1VE 0.00261 0.4596 3.89222
61 5MRH Q9Z 0.002474 0.44828 3.89222
62 1G51 AMO 0.00914 0.40332 3.89222
63 1QY1 PRZ 0.003109 0.41554 4.02299
64 4R78 AMP 0.00003258 0.54175 4.20712
65 4ZS4 ATP 0.00000007202 0.61746 4.23453
66 3ZJX BOG 0.004987 0.44056 4.49827
67 1T3D CYS 0.006495 0.43346 4.49827
68 4UWH JXM 0.001434 0.44475 4.79042
69 1UWK NAD 0.02085 0.40611 4.79042
70 1OBD ATP 0.0006586 0.46553 4.90196
71 2ET1 GLV 0.01404 0.41772 4.97512
72 2Z77 NCA 0.009118 0.42478 5.03597
73 2IO8 ADP 0.0003425 0.43539 5.08982
74 5A89 ADP 0.02268 0.40101 5.12821
75 5A89 FMN 0.02268 0.40101 5.12821
76 2IF8 ADP 0.00003227 0.54995 5.23416
77 2YW2 ATP 0.003295 0.4126 5.38922
78 3FSM 2NC 0.01297 0.40524 5.41872
79 3EXS 5RP 0.01692 0.40255 5.42986
80 4LO2 GAL BGC 0.002332 0.45661 5.44218
81 2GQS ADP 0.0003611 0.43951 5.48523
82 2GQR ADP 0.0004333 0.43519 5.48523
83 1I7L ATP 0.00009583 0.45741 5.50162
84 5GZ9 ANP 0.0000000007316 0.70095 5.57377
85 4XYM A12 0.00118 0.42743 5.68862
86 5W2I I3P 0.0001389 0.47716 5.83658
87 5W2I ADP 0.0001389 0.47716 5.83658
88 4DFU QUE 0.01968 0.40761 5.90062
89 5IQD RIO 0.0001103 0.50125 5.90164
90 5IQD GNP 0.0001028 0.50125 5.90164
91 5C4L SIS 0.00002923 0.51785 5.919
92 5C4L 4XR 0.00003374 0.51509 5.919
93 3V4S ATP 0.002873 0.41009 5.98802
94 2DTX BMA 0.01431 0.40843 5.98802
95 4CYI ATP 0.00001627 0.51016 6.28743
96 2VD9 IN5 0.005845 0.41263 6.28743
97 4WA2 SIA GAL NAG 0.03035 0.40009 6.28743
98 2GND MAN 0.02009 0.40945 6.74603
99 2XKO AKG 0.0055 0.4395 6.75676
100 4FFG 0U8 0.01489 0.41455 6.88623
101 1EHI ADP 0.001052 0.43761 7.18563
102 2QK4 ATP 0.0003665 0.41618 7.18563
103 2BKK ADP 0.000009668 0.48471 7.19697
104 3TM0 ANP 0.00004971 0.42745 7.22433
105 3TM0 B31 0.00005403 0.42159 7.22433
106 4ANW O92 0.0003813 0.46998 7.48503
107 2R7K AMZ 0.004536 0.4181 7.48503
108 5IH1 6BQ 0.007971 0.42736 7.61589
109 5IH1 GDP 0.007971 0.42736 7.61589
110 4OCJ NDG 0.00001327 0.54289 7.78443
111 4OCV ANP 0.00001127 0.51186 7.78443
112 4Z3X MTE 0.03515 0.40376 7.78443
113 4Z3X 4KX 0.03723 0.40376 7.78443
114 3G2Y GF4 0.02271 0.41897 7.98479
115 4Q5H ANP 0.0000003607 0.59474 8.04598
116 4LH7 1X8 0.001192 0.46766 8.04954
117 4O1P ANP 0.000000004772 0.63899 8.08383
118 1TQP ATP 0.000002824 0.51644 8.15603
119 3TDV GDP 0.00000005479 0.63086 8.16993
120 2UYN 2KT 0.01696 0.40639 8.52713
121 5IGI GMP 0.01057 0.41037 8.63787
122 5IGI ZIT 0.01115 0.41037 8.63787
123 4IX4 ADP 0.00000239 0.54537 8.68263
124 3DNT ATP 0.001331 0.43492 8.68263
125 3ORQ ADP 0.00108 0.43311 9.58084
126 3LQV ADE 0.01363 0.41207 10.2564
127 3VPD ANP 0.0008103 0.44041 10.3203
128 4U98 ACP 0.0001115 0.49027 10.479
129 3VOT ADP 0.0003248 0.42485 10.479
130 3LJU IP9 0.02703 0.40148 10.479
131 5C1P DAL DAL 0.001423 0.4354 10.7843
132 5C1P ADP 0.0003347 0.43047 10.7843
133 5LXT ACP 0.002489 0.40788 11.1888
134 4O4F ATP 0.00111 0.44007 11.2903
135 4O4F IHP 0.001213 0.44007 11.2903
136 3WVR AMP 0.00005479 0.467 11.3772
137 3SZB I1E 0.006056 0.43734 11.3772
138 3H0L ADP 0.005187 0.43228 11.7021
139 1N62 FAD 0.00679 0.42229 11.976
140 4AZW ATP 0.00002867 0.49975 12.2754
141 1E4E ADP 0.004117 0.40542 12.5749
142 5CKW ANP 0.000001996 0.50497 12.8743
143 4WW7 AMP 0.000001214 0.56055 13.7931
144 5JNN 6LM 0.002393 0.42395 14.7368
145 5U98 1KX 0.02975 0.406 15.1515
146 5L2J 6UL 0.04039 0.40261 15.3061
147 5L2J 70E 0.04261 0.40261 15.3061
148 3HAV ATP 0.0007996 0.44795 15.3846
149 4OAV ACP 0.00000001618 0.60751 15.8683
150 3KMW ATP 0.00005682 0.50348 16.6052
151 2FXD DR7 0.01224 0.40043 17.1717
152 5K2M ADP 0.00006888 0.49026 18.8679
153 1ZP9 ATP 0.0000004195 0.5471 18.9922
154 1ZTH ADP 0.0000001867 0.54132 18.9922
155 5MY8 RXZ 0.0000002666 0.5966 20.0599
156 3VHE 42Q 0.00000135 0.48513 20.9581
157 2CSN CKI 0.00000000002181 0.77671 24.2424
158 4P5Z Q7M 0.0000006036 0.60366 24.9307
159 3VPB ADP 0.000009017 0.48788 25
160 3E8N ATP 0.000000007523 0.47851 26.9461
161 3E8N VRA 0.000000007523 0.47851 26.9461
162 4FL3 ANP 0.00000000008903 0.71502 27.5449
163 1JPA ANP 0.0000001077 0.41349 28.2051
164 4CLI 5P8 0.00000005471 0.65967 28.7462
165 3H9R TAK 0.0000007706 0.49978 28.7879
166 4XH0 ADP 0.00000006559 0.69455 29.0419
167 3LXK MI1 0.0000002786 0.52809 29.052
168 5LXC 7AA 0.00000000008019 0.6826 29.3413
169 1VJY 460 0.00000001333 0.66802 29.3729
170 5C03 AGS 0.0000007951 0.55227 29.5322
171 3PP0 03Q 0.000002607 0.49794 29.6407
172 3NW7 LGV 0.0000001337 0.64495 29.6417
173 3C1X CKK 0.00001388 0.50347 30.2395
174 5EOB 5QQ 0.000000002635 0.73524 30.4075
175 5LPZ ADP 0.00000001329 0.62102 30.4217
176 4Y93 746 0.000000005238 0.6704 30.5389
177 1U59 STU 0.0000000117 0.66044 30.662
178 5KO1 6UY 0.00000009324 0.57722 30.7421
179 4KBA 1QM 0.00001407 0.46675 30.8157
180 4BTK DTQ 0.000008503 0.5116 30.8383
181 2XVD AS6 0.00000006526 0.63057 31.1258
182 1Y57 MPZ 0.00000008049 0.58262 31.1377
183 2H8H H8H 0.0000004998 0.55834 31.1377
184 5MJA 7O3 0.0000002484 0.5472 31.1475
185 4BHN BH9 0.00000004419 0.61865 31.4371
186 5T8O 76Z 0.0000001424 0.59717 31.5186
187 3UIM ANP 0.0000006804 0.55551 31.5951
188 1O9U ADZ 0.00000002834 0.71129 31.7365
189 5U6C 7YS 0.0000001983 0.59403 31.746
190 4BKJ STI 0.0008479 0.44513 31.746
191 4WOV 3SM 0.00002288 0.53451 31.8612
192 4YLL 4E3 0.0000000001388 0.73183 32.0359
193 2QLU ADE 0.000001188 0.62957 32.1656
194 4IDT T28 0.00000001988 0.65941 32.6347
195 3F7Z 34O 0.000000003924 0.64205 32.6347
196 4CRL C1I 0.0000003853 0.60509 32.6347
197 3ZRM ZRM 0.0000001042 0.5854 32.6347
198 2JLD AG1 0.00000000433 0.54757 32.6347
199 4NM5 ADP 0.0000346 0.53794 32.6347
200 3PLS ANP 0.0000000006749 0.66233 32.8859
201 4WNK 453 0.0000000001344 0.75129 32.9341
202 4AT3 LTI 0.0000001792 0.51072 33.4448
203 5LPB ADP 0.00000002963 0.56474 34.1216
204 1U5R ATP 0.0000000004632 0.73307 34.1317
205 4E93 GUI 0.000000006401 0.54398 34.1317
206 3VRY B43 0.000001495 0.5133 34.1317
207 1OPK P16 0.00001672 0.44342 34.1317
208 5HCY 60D 0.000000003113 0.71694 34.4411
209 3SRV S19 0.000000002087 0.64453 34.657
210 3LXN MI1 0.000000005089 0.65834 34.9057
211 3GNI ATP 0.00000003972 0.62061 35.0299
212 4ASE AV9 0.000002715 0.55744 35.0299
213 4F4P 0SB 0.0000006134 0.6285 35.1648
214 2F2U M77 0.000000003219 0.7283 35.3293
215 3ALN ANP 0.00000006896 0.61048 35.474
216 5UKL SIX 0.000000003309 0.6847 35.6287
217 3PVW QRX 0.000000005044 0.59709 35.6287
218 4YZC STU 0.000000003896 0.70073 35.9281
219 5USZ SKE 0.0000001571 0.61149 36.3322
220 2OO8 RAJ 0.0008363 0.43982 36.5931
221 3KRR DQX 0.000001891 0.60951 36.6102
222 2A19 ANP 0.000000002178 0.73651 36.6197
223 4GJ3 0XP 0.0000001305 0.62185 36.755
224 2Y6O 1N1 0.000005447 0.52013 37.1134
225 3KRL KRL 0.0000009088 0.56591 37.1257
226 5HES 032 0.0000005376 0.5756 37.1335
227 5FBN 5WF 0.00000001492 0.67026 37.2694
228 4AG8 AXI 0.000001131 0.45598 37.3418
229 2WU6 DKI 0.000000005265 0.63107 37.4251
230 3GC8 B45 0.000003044 0.53074 37.4251
231 1K3A ACP 0.00000001476 0.58739 37.4582
232 4U0I 0LI 0.00003582 0.51394 37.4603
233 5DBX ANP 0.0000000006126 0.63681 37.5
234 3BU5 ATP 0.0000000002552 0.6879 37.5817
235 5NKB 8ZT 0.0000005494 0.44127 37.5817
236 5BVE 4VG 0.0000000255 0.69674 37.7246
237 3GC0 AMP 0.0000001231 0.55267 37.9939
238 5CEO 50D 0.000001238 0.54285 38
239 4H3Q ANP 0.00000000001505 0.77311 38.024
240 4H3P ANP 0.000000003269 0.64619 38.024
241 3EKK GS2 0.00000002114 0.66759 38.1107
242 4Y85 499 0.000005694 0.50898 38.3234
243 5UOX 8GY 0.00000008471 0.60974 38.3764
244 2X2M X2M 0.00000002936 0.62932 38.535
245 5AWM ANP 0.0000001951 0.53747 38.6228
246 5JGA 6KC 0.000000009845 0.67387 38.7302
247 4E1Z 0MX 0.0000007933 0.54531 38.8316
248 4EWH T77 0.00000003709 0.55417 38.9091
249 5EKO N17 0.00002987 0.50367 38.9222
250 5X8I SQZ 0.0000000003913 0.68251 39.2216
251 5BYZ 4WE 0.0000001203 0.62342 39.2216
252 4L9I 8PR 0.00000002133 0.6047 39.521
253 1CM8 ANP 0.0000008321 0.58624 39.521
254 4QMN DB8 0.00000007111 0.64188 39.6774
255 2OFV 242 0.00001845 0.53336 39.7112
256 2QCS ANP 0.00000000005394 0.75961 39.8204
257 3FHI ANP 0.00000000008323 0.75143 39.8204
258 4OTH DRN 0.0000000002132 0.72031 39.8204
259 3GQI ACP 0.00000001088 0.66183 39.8773
260 5TO8 7FM 0.000001867 0.58307 40.0709
261 2PVF ACP 0.0000000004321 0.73443 40.1198
262 2GU8 796 0.000000003481 0.73102 40.1198
263 1RE8 BD2 0.000000003005 0.72122 40.1198
264 3IDB ANP 0.000000002087 0.64572 40.1198
265 5TA6 79D 0.000000204 0.60653 40.1198
266 4QTB 38Z 0.000000002237 0.58967 40.1198
267 4LOO SB4 0.000002207 0.56002 40.1198
268 3FC2 IBI 0.00002497 0.55844 40.1198
269 4WB7 ATP 0.00000000109 0.54641 40.1198
270 3SLS ANP 0.000000007234 0.63818 40.1316
271 4WB6 ATP 0.00000000003011 0.77062 40.4192
272 4NST ADP 0.00000002837 0.60956 40.4192
273 3TXO 07U 0.00000001577 0.5995 40.4192
274 5JFS 6K0 0.0000001419 0.63566 40.5844
275 5JKG 6LF 0.000001203 0.5901 40.836
276 4K33 ACP 0.0000000005281 0.68874 40.9231
277 1OUK 084 0.000001391 0.64183 41.018
278 5EFQ ADP 0.00000001191 0.62441 41.018
279 5HQ0 LZ9 0.00000001436 0.63929 41.0596
280 3E7O 35F 0.000004153 0.55721 41.3174
281 4YMJ 4EJ 0.0000002353 0.66559 41.4474
282 5H2U 1N1 0.00001421 0.49822 41.573
283 5LI1 ANP 0.00000000000406 0.79348 41.6168
284 5LI9 ACP 0.00000000001045 0.7832 41.6168
285 4DC2 ADE 0.000000004445 0.52241 41.6168
286 5DA3 58V 0.0000009015 0.60975 41.8868
287 2B9J ADP 0.000000004271 0.68954 41.9162
288 2B9I ADP 0.000000004772 0.67763 41.9162
289 2B9H ADP 0.000000007399 0.64219 41.9162
290 2B9F ADP 0.000000007645 0.63255 41.9162
291 4WHZ 3NL 0.00000342 0.58244 41.9162
292 3TTI KBI 0.000000009515 0.57687 41.9162
293 3PTG 932 0.0000001364 0.53301 41.9162
294 4TWP AXI 0.0000002206 0.63337 42.0664
295 3HMO STU 0.00000001205 0.66922 42.1053
296 5VC5 96M 0.00000004037 0.63726 42.2145
297 2HK5 1BM 0.0000001353 0.5981 42.2222
298 3G5D 1N1 0.00000006155 0.6721 42.3077
299 5UR1 YY9 0.00000005263 0.65877 42.4437
300 4UX9 ANP 0.000000000084 0.7337 42.515
301 4IZY 1J2 0.0000001885 0.59202 42.515
302 4AUA 4AU 0.00000096 0.53968 42.671
303 4XLI 1N1 0.000001496 0.52831 42.9104
304 4RFM 3P6 0.0000007217 0.40719 43.2331
305 3RI1 3RH 0.000000001624 0.69535 43.4505
306 2F57 23D 0.0000000195 0.58988 43.5331
307 3SXS PP2 0.0000002308 0.5883 43.6567
308 2BPM 529 0.000000002073 0.47323 43.6893
309 4CSV STI 0.00005158 0.49353 44
310 2V7O DRN 0.0000000005925 0.60766 44.012
311 3BZ3 YAM 0.00000009465 0.41184 44.2029
312 1ZY5 ANP 0.000002092 0.52338 44.2244
313 4CFU 2WC 0.00000001329 0.6771 44.5545
314 1BYG STU 0.000000000474 0.65157 44.6043
315 4BCQ TJF 0.0000001184 0.65245 44.8505
316 4BCM T7Z 0.0000004344 0.50343 44.8505
317 4AU8 Z3R 0.0000009905 0.60777 44.9324
318 4BCN T9N 0.00000003489 0.66766 45
319 3IGO ANP 0.000000000407 0.68841 45.2096
320 3SXF BK5 0.00000001356 0.67212 45.2096
321 1XJD STU 0.000000006788 0.64402 45.2096
322 2XMY CDK 0.0000003436 0.64611 45.302
323 5LMK 6ZK 0.000003386 0.50718 45.4545
324 5N87 N66 0.00000002616 0.66141 45.6869
325 3HZT J60 0.0000003318 0.63077 46.1078
326 1UNH IXM 0.00000001166 0.58761 46.2329
327 3O0G 3O0 0.00000007088 0.58259 46.2329
328 2WEL K88 0.00000002764 0.519 46.4832
329 4I6H 1C8 0.000001842 0.56349 47.0779
330 1V0O INR 0.00000001591 0.64578 47.2222
331 2ZV2 609 0.00000009665 0.65672 47.3154
332 5HX8 66P 0.0000001931 0.54138 47.351
333 2VZ6 FEF 0.00000006934 0.65356 47.9233
334 1PHK ATP 0.0000000001755 0.70904 47.9866
335 4D2S DYK 0.0000004293 0.52838 48.5915
336 4FG8 ATP 0.00000000009203 0.73203 49.5238
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