Receptor
PDB id Resolution Class Description Source Keywords
4AMV 2.05 Å EC: 2.6.1.16 E.COLI GLUCOSAMINE-6P SYNTHASE IN COMPLEX WITH FRUCTOSE-6P ESCHERICHIA COLI TRANSFERASE AMMONIA CHANNELING GLUCOSAMINE 6- PHOSPHATE SYN TERMINAL NUCLEOPHILE GLUTAMINE AMIDOTRANSFERASE
Ref.: GLUTAMINE BINDING OPENS THE AMMONIA CHANNEL AND ACT GLUCOSAMINE-6P SYNTHASE J.BIOL.CHEM. V. 281 4404 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
F6R B:1609;
C:1609;
A:1609;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
260.136 C6 H13 O9 P C([C@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4AMV 2.05 Å EC: 2.6.1.16 E.COLI GLUCOSAMINE-6P SYNTHASE IN COMPLEX WITH FRUCTOSE-6P ESCHERICHIA COLI TRANSFERASE AMMONIA CHANNELING GLUCOSAMINE 6- PHOSPHATE SYN TERMINAL NUCLEOPHILE GLUTAMINE AMIDOTRANSFERASE
Ref.: GLUTAMINE BINDING OPENS THE AMMONIA CHANNEL AND ACT GLUCOSAMINE-6P SYNTHASE J.BIOL.CHEM. V. 281 4404 2006
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4AMV - F6R C6 H13 O9 P C([C@H]([C....
2 2J6H - G6Q C6 H13 O9 P C([C@H]([C....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4AMV - F6R C6 H13 O9 P C([C@H]([C....
2 2J6H - G6Q C6 H13 O9 P C([C@H]([C....
50% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2POC - BG6 C6 H13 O9 P C([C@@H]1[....
2 2PUV - M6R C6 H16 N O8 P C([C@H]([C....
3 2PUT - F6R C6 H13 O9 P C([C@H]([C....
4 1MOQ Ki = 0.35 mM GLP C6 H14 N O8 P C([C@@H]1[....
5 1MOS - AGP C6 H16 N O8 P C([C@@H]([....
6 1MOR - G6P C6 H13 O9 P C([C@@H]1[....
7 4AMV - F6R C6 H13 O9 P C([C@H]([C....
8 2J6H - G6Q C6 H13 O9 P C([C@H]([C....
9 2ZJ3 - G6P C6 H13 O9 P C([C@@H]1[....
10 2ZJ4 - AGP C6 H16 N O8 P C([C@@H]([....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: F6R; Similar ligands found: 47
No: Ligand ECFP6 Tc MDL keys Tc
1 F6R 1 1
2 TG6 1 1
3 I22 0.74359 1
4 2FP 0.7 0.971429
5 P6F 0.7 0.971429
6 P6T 0.7 0.971429
7 HMS 0.641026 0.972222
8 PA5 0.641026 0.916667
9 5RP 0.641026 0.972222
10 5SP 0.641026 0.972222
11 R10 0.641026 0.916667
12 PAN 0.581395 0.6875
13 M2P 0.555556 0.942857
14 6PG 0.534884 0.916667
15 LG6 0.534884 0.916667
16 TAG 0.5 0.628571
17 FUD 0.5 0.628571
18 LPK 0.5 0.628571
19 LX1 0.5 0.837838
20 SDD 0.5 0.628571
21 PSJ 0.5 0.628571
22 KD0 0.5 0.916667
23 DX5 0.5 0.916667
24 SOL 0.5 0.628571
25 A5P 0.5 0.916667
26 LXP 0.5 0.916667
27 DEZ 0.487805 0.916667
28 S6P 0.487805 0.942857
29 DER 0.487805 0.916667
30 RUB 0.477273 0.916667
31 XBP 0.477273 0.916667
32 DXP 0.47619 0.837838
33 TX4 0.465116 0.645833
34 DG6 0.465116 0.891892
35 R52 0.465116 0.942857
36 R5P 0.465116 0.942857
37 HG3 0.459459 0.805556
38 52L 0.44898 0.702128
39 M6R 0.444444 0.767442
40 AGP 0.444444 0.767442
41 RES 0.444444 0.6875
42 G6Q 0.444444 0.942857
43 4TP 0.431818 0.767442
44 LRY 0.423077 0.733333
45 H4P 0.42 0.790698
46 1NT 0.407407 0.916667
47 E4P 0.404762 0.885714
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4AMV; Ligand: F6R; Similar sites found: 478
This union binding pocket(no: 1) in the query (biounit: 4amv.bio1) has 37 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1PTR PRB 0.002537 0.44072 None
2 4F4S EFO 0.001925 0.4265 None
3 2E1A MSE 0.007783 0.41765 None
4 1QD0 RR6 0.002174 0.40873 None
5 3FJO FMN 0.004194 0.41915 1.14943
6 3QV9 QV7 0.000185 0.47549 1.2024
7 3QO8 SSA 0.001155 0.40935 1.23711
8 3F3E LEU 0.000334 0.46121 1.34875
9 3JQ3 ADP 0.0003412 0.44432 1.36612
10 1H2B OCA 0.004851 0.41558 1.39276
11 3GWT 066 0.00454 0.41007 1.41643
12 2CKM AA7 0.0119 0.40471 1.4733
13 2HGS ADP 0.001936 0.41164 1.47679
14 2ZWS PLM 0.001255 0.49308 1.47783
15 1TLL FMN 0.006732 0.41499 1.47783
16 2AMV BIN 0.01512 0.40723 1.47783
17 3WO0 ADP 0.004573 0.41593 1.48936
18 3WO0 ALA 0.004573 0.41593 1.48936
19 1JH7 UVC 0.002966 0.42462 1.5873
20 3PJU C2E 0.004227 0.40573 1.60643
21 1WDA BAG 0.001807 0.42197 1.64204
22 2IZ1 ATR 0.002512 0.43401 1.68776
23 2D37 FMN 0.004009 0.40658 1.70455
24 2Q1A 2KT 0.001387 0.44531 1.70648
25 3L6R MLI 0.002113 0.44433 1.7341
26 2WET FAD 0.03734 0.40002 1.76125
27 3I0O SMI 0.002755 0.42597 1.76991
28 2Y7G AAE 0.001226 0.40845 1.77305
29 1X54 4AD 0.002801 0.40922 1.84332
30 1YBH FAD 0.0009503 0.44588 1.86441
31 1YBH P22 0.006362 0.40451 1.86441
32 2IMP NAI 0.03139 0.4085 1.87891
33 1Q11 TYE 0.003045 0.41838 1.88172
34 3NKS ACJ 0.0007863 0.41518 1.88679
35 1F8F NAD 0.01592 0.40925 1.88679
36 2XVE FAD 0.00205 0.45031 1.93966
37 1IYE PGU 0.002965 0.41709 1.94175
38 2YG3 FAD 0.02281 0.4089 1.98676
39 2VQ5 HBA 0.004041 0.43151 1.99005
40 2F2U M77 0.002165 0.41367 1.99005
41 2VQ5 LDP 0.02209 0.41005 1.99005
42 1AUA BOG 0.007831 0.40161 2.02703
43 4WBD CIT 0.003125 0.44397 2.03327
44 4WBD ADP 0.002627 0.44002 2.03327
45 1E4E PHY 0.0008524 0.41395 2.04082
46 3D3W NAP 0.0001319 0.47132 2.04918
47 4K5S PM0 0.006077 0.4225 2.05224
48 4K5S FAD 0.002498 0.4225 2.05224
49 3B9Z CO2 0.006192 0.41683 2.06186
50 3WE0 FAD 0.009067 0.41122 2.06897
51 3B1F NAD 0.002548 0.40732 2.06897
52 1CBF SAH 0.001359 0.40689 2.10526
53 2OWZ CIT 0.0004125 0.46835 2.10843
54 2Q8M BG6 0.007737 0.42532 2.10843
55 1JN2 SFP 0.004172 0.45744 2.1097
56 1NJR XYL 0.002219 0.44352 2.11268
57 2QS8 MET 0.004882 0.4034 2.15311
58 3V1U NAD 0.004867 0.40196 2.1645
59 2PFC PLM 0.001607 0.41359 2.18579
60 1T8U UAP SGN IDS SGN 0.00268 0.42716 2.20588
61 1ZUW DGL 0.0001199 0.41931 2.20588
62 2YVF NAD 0.01435 0.41514 2.20588
63 2YVF FAD 0.0171 0.41132 2.20588
64 1WVG APR 0.0001745 0.4553 2.22841
65 1YS4 NAP 0.0001833 0.44872 2.25989
66 1UXG NAD 0.003474 0.42276 2.26537
67 1UXG FUM 0.003474 0.42276 2.26537
68 3D9F FAD 0.02472 0.41523 2.28311
69 1H16 PYR 0.0006013 0.47784 2.29885
70 1R37 NAD 0.005586 0.4103 2.30548
71 4C0C WVH 0.003788 0.42725 2.35546
72 1Z42 HBA 0.003044 0.47367 2.36686
73 1Z44 NPO 0.02385 0.42354 2.36686
74 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.02056 0.40512 2.38095
75 1H5R G1P 0.006286 0.41325 2.38908
76 2C7G ODP 0.002261 0.44401 2.41228
77 2C7G FAD 0.002364 0.44401 2.41228
78 4COQ SAN 0.0002217 0.48015 2.42915
79 1XVV CCQ 0.002583 0.42887 2.45098
80 1NML CIT 0.000885 0.44027 2.45399
81 1C7R PA5 0.003325 0.40105 2.47191
82 2ZJF BSU 0.001198 0.42349 2.48619
83 2CXS F6P 0.000002351 0.56856 2.51346
84 4PO2 ASN ARG LEU LEU LEU THR GLY 0.003073 0.40437 2.55319
85 1PEA ACM 0.01998 0.40572 2.5974
86 3Q9T FAY 0.002341 0.42946 2.59965
87 2HGZ PBF 0.001473 0.41947 2.61438
88 2O2C G6Q 0.000000984 0.57382 2.62726
89 1WNG SAH 0.0001313 0.42138 2.64151
90 2H6T IVA VAL VAL STA ALA STA 0.0008345 0.4166 2.64706
91 3K3G MMU 0.004676 0.41346 2.64706
92 2W8Q SIN 0.0006127 0.46876 2.6694
93 2GWD GLU 0.001443 0.42582 2.67261
94 1XX4 BAM 0.0007284 0.48335 2.68199
95 1OAA OAA 0.001892 0.4383 2.7027
96 2XI7 XI7 0.0004059 0.51964 2.71739
97 2HXT EHM 0.001071 0.40673 2.72109
98 3F81 STT 0.0002731 0.50436 2.73224
99 1DLJ UGA 0.0009797 0.45541 2.73632
100 1DLJ NAI 0.006245 0.42284 2.73632
101 2XDQ MGX 0.001234 0.47205 2.73973
102 3WCS MAN NAG GAL 0.0001048 0.4639 2.75591
103 3WCS MAN NAG 0.00252 0.42174 2.75591
104 1TUF AZ1 0.004438 0.40188 2.76498
105 4OYA 1VE 0.01971 0.42458 2.76596
106 1FW1 GSH 0.002636 0.40111 2.77778
107 4CCO OGA 0.002691 0.42057 2.78373
108 2RCN GDP 0.00245 0.41162 2.7933
109 1E7S NAP 0.006069 0.40653 2.80374
110 2Z9V PXM 0.002141 0.42462 2.80612
111 2P4Q FLC 0.007777 0.41249 2.8169
112 2HFK E4H 0.001784 0.42786 2.82132
113 4HZO COA 0.0006795 0.44495 2.83019
114 1ZFJ IMP 0.003349 0.42844 2.85132
115 1I9G SAM 0.002079 0.43859 2.85714
116 4JWX 1N4 0.01932 0.40252 2.85714
117 2ZYF AKG 0.004388 0.40675 2.87958
118 2DWU DGL 0.0004537 0.44564 2.89855
119 1AX2 NDG GAL 0.0003239 0.45807 2.92887
120 2Q8H TF4 0.0003678 0.49799 2.9484
121 3AHC TPP 0.003325 0.41387 2.95567
122 3CQ5 PMP 0.000465 0.44522 2.98103
123 2BO4 FLC 0.003353 0.4352 3.02267
124 3BL6 FMC 0.0006743 0.4221 3.04348
125 1PL6 NAD 0.0006851 0.42799 3.08989
126 1PL6 572 0.002044 0.42583 3.08989
127 1X8X TYR 0.004717 0.40074 3.10559
128 3TFC PEP 0.003134 0.41786 3.11688
129 4RJK PYR 0.02462 0.40137 3.11987
130 1FP2 SAH 0.001327 0.41183 3.125
131 3MB5 SAM 0.002805 0.43692 3.13725
132 3DGB MUC 0.001765 0.41207 3.14136
133 4IXW IXW 0.00167 0.42332 3.14961
134 1H8G CHT 0.00674 0.45347 3.15789
135 1GSA GSH 0.002495 0.43154 3.16456
136 1GSA ADP 0.01038 0.41229 3.16456
137 1A5V Y3 0.009572 0.40308 3.16456
138 3TKA CTN 0.006101 0.45927 3.17003
139 3TKA SAM 0.0001317 0.41419 3.17003
140 4PKG ATP 0.005367 0.41431 3.18302
141 3SJH ATP 0.005602 0.41527 3.2
142 1ZJ6 G3D 0.001452 0.41521 3.20856
143 1EYE PMM 0.003052 0.40327 3.21429
144 1E5F PLP 0.0009566 0.41221 3.21782
145 4OE4 NAD 0.003225 0.41505 3.27586
146 2FOI JPA 0.0006731 0.43306 3.33333
147 2FF3 ATP 0.006376 0.41092 3.33333
148 3MN5 ATP 0.005878 0.41433 3.34262
149 4QVH FLC 0.03002 0.4202 3.34448
150 2CE7 ADP 0.00181 0.40698 3.36134
151 4N02 FNR 0.0216 0.40237 3.36134
152 4C2G ALA ALA ALA ALA 0.002915 0.41377 3.36323
153 4Q3R XA2 0.002758 0.41108 3.37662
154 4IOK XPO 0.003008 0.40643 3.39893
155 4IOK ADP 0.004046 0.40643 3.39893
156 1MZV AMP 0.002536 0.41104 3.40426
157 2C0U FAD NBT 0.02026 0.40859 3.41686
158 3UEC ALA ARG TPO LYS 0.003836 0.43254 3.42466
159 2FR6 CTN 0.0004307 0.41018 3.42466
160 3O03 NAP 0.00387 0.40715 3.43643
161 1QH9 LAC 0.004905 0.42127 3.44828
162 2NVK NAP 0.001898 0.42676 3.48361
163 1H6W SER LEU ASN TYR ILE ILE LYS VAL LYS GLU 0.0005535 0.46497 3.52564
164 1U7Z PMT 0.0005066 0.44899 3.53982
165 2EWM NAD 0.002592 0.4193 3.61446
166 3B9Q MLI 0.009607 0.42358 3.64238
167 2C4I BTN 0.0009174 0.41284 3.69004
168 2RC8 DSN 0.008367 0.41903 3.7415
169 1BTN I3P 0.0003822 0.53016 3.77358
170 1TU3 GNP 0.000232 0.45074 3.79747
171 1EB9 HBA 0.003352 0.40176 3.81679
172 3SSO SAH 0.001474 0.41406 3.81862
173 2VAR AMP 0.001318 0.42191 3.83387
174 2VAR KDG 0.001919 0.41073 3.83387
175 2VAR ANP 0.000429 0.40007 3.83387
176 1RZM E4P 0.002299 0.44266 3.84615
177 4DN8 BMA 0.001987 0.43847 3.84615
178 1RZM PEP 0.002685 0.42061 3.84615
179 2A42 ATP 0.006242 0.41134 3.84615
180 2A3Z ATP 0.006728 0.40987 3.84615
181 3GE7 AFQ 0.001424 0.43183 3.88601
182 1SQ5 PAU 0.0007966 0.44214 3.8961
183 1G8S MET 0.002016 0.4382 3.91304
184 3VPD ANP 0.0002874 0.4396 3.91459
185 3ICC NAP 0.00269 0.42 3.92157
186 3LTW HLZ 0.001827 0.44006 3.92857
187 4CBX ATP 0.007444 0.40788 3.93701
188 1XE7 GUN 0.00792 0.43217 3.94089
189 2DKH FAD 0.001959 0.42654 3.94089
190 2JC9 ADN 0.004062 0.41327 3.94089
191 2DKH 3HB 0.007124 0.41158 3.94089
192 4M2K PLP 0.000261 0.41047 3.94089
193 2YC5 6BC 0.0006304 0.448 3.94737
194 1SOW NAD 0.002291 0.42266 3.96341
195 4USS GSH 0.003907 0.41396 4
196 2JAR UMP 0.0004433 0.40965 4
197 1OFH ADP 0.01621 0.41098 4.02299
198 1R6W 164 0.001394 0.40651 4.03727
199 1EYQ NAR 0.0001926 0.46032 4.05405
200 3I51 45C 0.002269 0.40803 4.07407
201 3CXO 1N5 0.00462 0.40979 4.09639
202 1HSJ GLC 0.04516 0.40826 4.10678
203 4PL8 ATP 0.006251 0.41131 4.10959
204 3ITJ FAD 0.03441 0.4065 4.14201
205 3SVL FMN 0.002401 0.40046 4.14508
206 3H86 AP5 0.007674 0.41631 4.16667
207 3JDW ORN 0.0001224 0.44334 4.25532
208 2B82 ADN 0.003588 0.40015 4.2654
209 3FXU TSU 0.0001461 0.45627 4.26929
210 1LSS NAD 0.0001304 0.41431 4.28571
211 2Q3M MLA 0.0004642 0.493 4.29448
212 3SQG COM 0.009887 0.43537 4.30108
213 3MJY FMN 0.0127 0.413 4.33526
214 1ZED PNP 0.007074 0.42044 4.33884
215 3GTD MLI 0.0001547 0.47877 4.35685
216 2BLE 5GP 0.00122 0.45815 4.35967
217 3DG6 MUC 0.001343 0.41164 4.35967
218 3R51 MMA 0.00003755 0.54685 4.375
219 4NTD FAD 0.002391 0.4291 4.41176
220 1DKU AP2 0.002576 0.41447 4.4164
221 4IVG ANP 0.01407 0.40851 4.4335
222 3KV4 OGA 0.0181 0.4054 4.47427
223 2GSD NAD 0.002219 0.42692 4.47761
224 1KOJ PAN 0.000001345 0.57683 4.48833
225 4B16 NAG 0.002819 0.46356 4.51128
226 4O8A 2OP 0.004383 0.44487 4.51237
227 4R33 TRP 0.007989 0.40316 4.52381
228 4R33 SAH 0.007989 0.40316 4.52381
229 1I7L ATP 0.004187 0.40119 4.53074
230 2DTX BMA 0.001154 0.44257 4.54545
231 3PFG TLO 0.002967 0.42755 4.56274
232 3PFG SAM 0.002967 0.42755 4.56274
233 3RKR NAP 0.0007104 0.401 4.58015
234 1H8P PC 0.00302 0.45287 4.58716
235 2NLI LAC 0.01779 0.40436 4.61957
236 2NLI FMN 0.01779 0.40436 4.61957
237 4B9E FAH 0.001533 0.45066 4.65116
238 1RYD GLC 0.00287 0.43148 4.65116
239 1ULE GLA GAL NAG 0.004817 0.43507 4.66667
240 1C0I BE2 0.002182 0.43775 4.6832
241 1C0I FAD 0.002182 0.43775 4.6832
242 1KTC NGA 0.000922 0.43955 4.69136
243 3GJB AKG 0.001154 0.42964 4.70219
244 3ZPG 5GP 0.009793 0.4276 4.71204
245 1B55 4IP 0.0004602 0.42835 4.73373
246 3CBG SAH 0.001268 0.41021 4.74138
247 1TDF NAP 0.01295 0.42183 4.74684
248 4GYW UDP 0.003952 0.41488 4.7619
249 1I0Z OXM 0.003445 0.45004 4.8048
250 3LZW NAP 0.002559 0.44412 4.81928
251 3LZW FAD 0.001678 0.4351 4.81928
252 3L24 GOA 0.002529 0.45667 4.83559
253 3IB8 AMP 0.001537 0.40064 4.84848
254 4B7E OGA 0.002252 0.42967 4.87106
255 4L7I SAM 0.0003586 0.42011 4.914
256 1H9G COA MYR 0.0002064 0.4544 4.93827
257 3NNF AKG 0.001674 0.44173 4.94186
258 2Z9C FMN 0.009221 0.40367 5
259 2V7T SAH 0.002249 0.46204 5.01672
260 1KOL NAD 0.01075 0.40152 5.02513
261 4KCF FMN 0.001072 0.41048 5.06608
262 1C1L GAL BGC 0.005052 0.4271 5.10949
263 2YBQ SAH 0.0004913 0.42915 5.13699
264 2YBQ UP2 0.002926 0.42345 5.13699
265 2WMO GTP 0.002579 0.40146 5.14019
266 1TIW TFB 0.006508 0.4121 5.1495
267 1TIW FAD 0.006508 0.4121 5.1495
268 1V2X SAM 0.00178 0.40918 5.15464
269 4LO6 SIA GAL 0.01251 0.4122 5.26316
270 3BHO B4P 0.04232 0.40242 5.28846
271 2QCX PF1 0.003983 0.4192 5.32319
272 3U4C NDP 0.0005538 0.4417 5.33808
273 3MN9 ATP 0.005889 0.41249 5.34759
274 3A1I UNU 0.001148 0.4242 5.37428
275 4M5P MLA 0.001988 0.4714 5.40541
276 1C4U IH1 0.0007882 0.42077 5.40541
277 1O0D 163 0.001773 0.40509 5.40541
278 3DDC GNP 0.002882 0.41037 5.42169
279 1O9U ADZ 0.003599 0.44911 5.42857
280 3C3N FMN 0.0241 0.4029 5.44872
281 2EFJ SAH 0.001715 0.4056 5.46875
282 1RYI GOA 0.007985 0.45269 5.49738
283 2JFV FLC 0.001038 0.45081 5.49828
284 3FPZ AHZ 0.0031 0.45168 5.52147
285 1X92 M7P 0.0007296 0.43391 5.52764
286 2HMT NAI 0.002847 0.43493 5.55556
287 3SCH TB6 0.007039 0.41439 5.55556
288 4PKI ATP 0.006359 0.41098 5.55556
289 1YAG ATP 0.006899 0.4145 5.6
290 2DTJ THR 0.0002266 0.45111 5.61798
291 4KQI NIO 0.004698 0.40951 5.61798
292 4KQI RBZ 0.004698 0.40951 5.61798
293 2P1M IHP 0.003405 0.40769 5.625
294 2OHV NHL 0.001463 0.42559 5.68182
295 9LDB NAD 0.002465 0.42013 5.72289
296 9LDT OXM 0.03553 0.40642 5.72289
297 2YIV NBN 0.0004851 0.47337 5.74713
298 2YIV YIV 0.0007948 0.47211 5.74713
299 1YHM AHD 0.005666 0.41273 5.80111
300 1TOI HCI 0.006456 0.40167 5.80808
301 4GQB 0XU 0.02299 0.40126 5.81395
302 1SS4 GSH 0.00005558 0.57732 5.88235
303 4LIT AKG 0.004468 0.41709 5.89681
304 1WUR 8DG 0.003955 0.4004 5.90909
305 1OTH PAO 0.003464 0.41582 5.919
306 2PT9 2MH 0.004988 0.41219 5.919
307 2PT9 S4M 0.004673 0.40261 5.919
308 1POC GEL 0.0008533 0.40841 5.97015
309 3RFV 15L 0.004098 0.40623 5.99251
310 1JAC AMG 0.0005948 0.49845 6.01504
311 3QQA TCH 0.000934 0.42311 6.01852
312 1XHL NDP 0.007092 0.40395 6.06061
313 3I8P 840 0.001262 0.40801 6.08899
314 4N65 FMN 0.01123 0.41185 6.13208
315 3L8H FX1 0.009222 0.41883 6.14525
316 1EDO NAP 0.01507 0.41789 6.14754
317 4EXO PYR 0.008951 0.42231 6.16438
318 3MAG 3MA 0.01043 0.43416 6.18893
319 1QF5 GDP 0.003557 0.43104 6.2645
320 1QF5 RPL 0.003557 0.43104 6.2645
321 1Y7P RIP 0.02455 0.40143 6.27803
322 2VPR TDC 0.0018 0.40263 6.28019
323 1YOA FMN 0.0004401 0.51774 6.28931
324 1DXY COI 0.01284 0.42177 6.30631
325 2VDJ HSE 0.00154 0.45852 6.31229
326 4AF5 CIT 0.0001233 0.49129 6.31579
327 4W6Z ETF 0.00163 0.46609 6.34006
328 1B8U OAA 0.005245 0.40895 6.38298
329 1QZZ SAM 0.002172 0.40413 6.41711
330 1I2B USQ 0.002796 0.44024 6.43564
331 1I2B NAD 0.002796 0.44024 6.43564
332 1I2B UPG 0.002796 0.44024 6.43564
333 3TO7 COA 0.004635 0.41787 6.52174
334 2QV7 ADP 0.0009451 0.41239 6.52819
335 3O7B SAH 0.0001484 0.42696 6.55738
336 1NVU GTP 0.01116 0.41559 6.65281
337 3ZGE ASP 0.001967 0.45349 6.73235
338 3CQD ATP 0.007562 0.40852 6.79612
339 4F8L GAL 0.03255 0.41612 6.89655
340 3RF4 FUN 0.005822 0.40688 6.89655
341 1LTH NAD 0.01876 0.40489 6.89655
342 4EKV BTN 0.002104 0.42535 6.91824
343 1KYQ NAD 0.0004668 0.40912 6.93431
344 1HEX NAD 0.001036 0.42998 6.95652
345 4LSJ LSJ 0.0009747 0.42053 6.97674
346 2Q97 ATP 0.006438 0.41424 6.97674
347 1L1Q 9DA 0.002486 0.404 6.98925
348 2XBL M7P 0.0003336 0.4618 7.07071
349 2BOI MFU 0.0003008 0.45939 7.07965
350 2F01 BTN 0.003745 0.44147 7.08661
351 2F01 BTQ 0.01688 0.41404 7.08661
352 3A2Q ACA ACA 0.0005094 0.42414 7.09939
353 1Q3Q ANP 0.007324 0.42311 7.11679
354 3LST SAH 0.00147 0.41501 7.18391
355 3OZG SSI 0.0007005 0.41693 7.2
356 1GJW GLC 0.0005554 0.4707 7.22496
357 1GJW MAL 0.0006761 0.43298 7.22496
358 3BRE C2E 0.0003022 0.47426 7.26257
359 1UZN NAP 0.0007716 0.41546 7.28745
360 3GEG NAD 0.00401 0.40803 7.28745
361 3PMA SCR 0.002757 0.42014 7.33591
362 2PWY SAH 0.0004111 0.43795 7.36434
363 2X61 CH 0.003455 0.42391 7.36434
364 2EB5 OXL 0.002627 0.43316 7.49064
365 1A27 EST 0.0005317 0.4211 7.61246
366 4Q3F TLA 0.01045 0.40684 7.69231
367 4LWA Q13 0.002834 0.42729 7.7135
368 2C2A ADP 0.0005082 0.41429 7.75194
369 1NZY BCA 0.002868 0.41347 7.80669
370 1SC3 MLI 0.0007965 0.47206 7.95455
371 2XBP ATP 0.01283 0.40733 7.9646
372 4NAO AKG 0.002027 0.44515 7.97546
373 3CEV ARG 0.001103 0.43042 8.02676
374 1GU3 BGC BGC BGC BGC BGC 0.0008873 0.44023 8.05369
375 3PNL ADP 0.002566 0.40721 8.05687
376 1T0S BML 0.005358 0.43288 8.13953
377 1P9B IMO 0.001637 0.41779 8.1448
378 1NW5 SAM 0.0002829 0.43771 8.15047
379 4DQ2 BTX 0.004314 0.40825 8.23171
380 1KBJ FMN 0.002905 0.41024 8.25243
381 1D6H COA 0.003506 0.42765 8.26873
382 4M51 BEZ 0.001252 0.46277 8.43091
383 4BAS GNP 0.0002156 0.44409 8.54271
384 1FIQ FAD 0.003856 0.41649 8.57143
385 1FIQ SAL 0.005675 0.40764 8.57143
386 1FIQ MTE 0.004861 0.40764 8.57143
387 4DYO SD4 0.00491 0.40482 8.65979
388 1Y1A GSH 0.009086 0.44945 8.74317
389 5EQU AKG 0.02166 0.40404 8.85246
390 2VKL MLT 0.02346 0.41586 8.88889
391 3S2Y FMN 0.002595 0.40135 9.04523
392 3OCZ SRA 0.0009844 0.40464 9.16031
393 1VQ2 DDN 0.0002331 0.4253 9.32642
394 2C31 ADP 0.0146 0.41962 9.33099
395 2C31 TZD 0.02901 0.40743 9.33099
396 1I1Q TRP 0.003891 0.40881 9.375
397 1II5 GLU 0.0001418 0.40635 9.44206
398 3I6B KDO 0.002803 0.41984 9.44444
399 2YLD CMO 0.005579 0.41882 9.44882
400 4G6I RS3 0.02284 0.40081 9.52381
401 2O66 FLC 0.003222 0.42309 9.62963
402 1TUV VK3 0.002526 0.4567 9.64912
403 4HSU FAD 0.037 0.40185 9.67742
404 3U1T MLI 0.002148 0.444 9.70874
405 1V35 NAI 0.03464 0.4008 9.72644
406 2ALG DAO 0.002472 0.40598 9.78261
407 2ALG HP6 0.002472 0.40598 9.78261
408 2PR5 FMN 0.0001469 0.42517 9.84848
409 2V5E SCR 0.01389 0.42771 10
410 2GJ3 FAD 0.0006137 0.4257 10
411 4G4S LDZ 0.0003909 0.41888 10.0694
412 2PAV ATP 0.009561 0.41644 10.0719
413 2Y7P SAL 0.005617 0.40751 10.0917
414 3H22 B53 0.0004276 0.40973 10.7744
415 4INB 1F6 0.0006115 0.42576 10.9589
416 4A6D SAM 0.002645 0.40303 11.0482
417 4E28 9MZ 0.006659 0.41545 11.0769
418 4E28 0MZ 0.008382 0.40553 11.0769
419 3WBF NAP 0.003866 0.41004 11.1475
420 4HZD COA 0.004806 0.41397 11.3475
421 1OGD RIP 0.004258 0.41243 11.4504
422 3DCM SAM 0.0009101 0.41959 11.4583
423 1VDC FAD 0.005109 0.42471 11.7117
424 2HW1 ANP 0.0002306 0.44304 11.745
425 2W3L DRO 0.01216 0.42295 11.8056
426 3EW2 BTN 0.003007 0.41323 11.8519
427 3QDY A2G GAL 0.0002823 0.49336 11.8881
428 3QDT A2G GAL 0.0006122 0.47747 11.8881
429 3QDY CBS 0.001877 0.44667 11.8881
430 1O68 KIV 0.004674 0.41078 12
431 2QLX RM4 0.00272 0.43934 12.037
432 1V6A TRE 0.003091 0.42386 12.0482
433 4G28 0W8 0.002425 0.41692 12.0805
434 2B4Q NAP 0.002699 0.41729 12.3188
435 2OYS FMN 0.0007659 0.42429 12.3967
436 1NF8 ISC 0.001989 0.41016 12.5604
437 3RGG AIR 0.002947 0.40855 12.5786
438 1DL7 NCH 0.044 0.40889 12.844
439 1CT9 GLN 0.003027 0.40378 13.0199
440 3P7I P7I 0.0005588 0.44842 13.0841
441 1W7J ADP BEF 0.0001648 0.43093 13.245
442 2Q37 3AL 0.0008112 0.44839 13.2597
443 3PNA CMP 0.001527 0.42485 13.6364
444 1WRA PC 0.01117 0.41139 13.6364
445 1ECM TSA 0.00252 0.41626 13.7615
446 2UZ2 BTN 0.00214 0.40001 13.8462
447 2D0V PQQ 0.002548 0.40361 13.8889
448 3T2W BTN 0.004644 0.401 13.9344
449 4CCN OGA 0.01256 0.40333 14.2857
450 1Y75 NAG 0.002936 0.41364 14.4068
451 3TA2 AKG 0.005021 0.40577 14.4068
452 1YRX FMN 0.0001801 0.43749 14.876
453 1A69 FMB 0.02915 0.40224 15.126
454 4JLV ADP 0.00807 0.44443 15.2416
455 1QO0 BMD 0.00133 0.44611 15.3061
456 4LZJ 22H 0.0001504 0.49271 15.5116
457 2V52 ATP 0.00576 0.41473 15.625
458 3W54 RNB 0.0002069 0.44081 16.1094
459 4JP3 CIT 0.00152 0.41448 16.7364
460 2WCI GSH 0.009513 0.4032 17.037
461 3HUJ AGH 0.04032 0.40076 18.1818
462 2OFE NAG 0.00154 0.44332 18.3099
463 2OFD NGA 0.003301 0.42881 18.3099
464 3S9K CIT 0.005711 0.45031 18.6441
465 1ECC PCP 0.0003412 0.4409 19.0476
466 2JBH 5GP 0.003231 0.412 19.1111
467 4IVN BMX 0.000002044 0.54623 19.7842
468 1X9I G6Q 0.000002169 0.57404 20.1987
469 4KGM ATP 0.003469 0.4012 20.4082
470 3BY8 MLT 0.001881 0.44662 20.4225
471 3E81 SLB 0.004709 0.41613 21.3415
472 1Y2W NAG 0.00208 0.4376 22.5352
473 1JUV NDP 0.001191 0.42615 25.3886
474 2FF6 ATP 0.005441 0.41404 26.9231
475 4B1Y ATP 0.007372 0.41155 34.375
476 2A40 ATP 0.00694 0.40926 34.375
477 1UO4 PIH 0.007767 0.44081 38.2353
478 1UO5 PIH 0.01371 0.43669 41.1765
Pocket No.: 2; Query (leader) PDB : 4AMV; Ligand: F6R; Similar sites found: 27
This union binding pocket(no: 2) in the query (biounit: 4amv.bio2) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5IN3 G1P 0.0131 0.41034 0.997506
2 1LCF OXL 0.01352 0.40154 1.97044
3 1RP0 AHZ 0.02332 0.40037 2.11268
4 2ZKJ ADP 0.02328 0.40661 2.28426
5 5FA6 FMN 0.03259 0.4201 2.29885
6 5FA6 NAP 0.03334 0.4201 2.29885
7 5FA6 FAD 0.03259 0.4201 2.29885
8 4B2D FBP 0.005398 0.40822 2.73723
9 5HWK BEZ 0.02472 0.40072 3.33333
10 3FC4 EDO 0.03492 0.40901 3.77668
11 4AT0 FAD 0.03995 0.40248 3.92157
12 4IP7 FBP 0.004398 0.41217 4.05157
13 1N62 MCN 0.02484 0.40328 4.21687
14 4H2D FMN 0.00422 0.40158 4.24242
15 3MJY IJZ 0.01691 0.40707 4.33526
16 4TQK NAG 0.01004 0.41819 4.92611
17 5DEX 5E0 0.01253 0.40408 5.47945
18 4WXJ GLU 0.001487 0.4586 5.57621
19 4RL4 PPV 0.01174 0.42375 5.66038
20 2GAG NAD 0.03023 0.40009 8.14815
21 5O4F 8VE 0.004017 0.41799 8.52713
22 1YC5 NCA 0.01723 0.40178 8.53659
23 3HRD MCN 0.02043 0.40534 8.75
24 3KAP FMN 0.005982 0.41398 10.2041
25 5IKB KAI 0.001591 0.42273 12.4514
26 2XOD FMN 0.008853 0.40447 14.2857
27 4BMO FMN 0.01092 0.40832 15.126
Pocket No.: 3; Query (leader) PDB : 4AMV; Ligand: F6R; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4amv.bio2) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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