Receptor
PDB id Resolution Class Description Source Keywords
4ADD 2.45 Å EC: 2.6.1.17 STRUCTURAL AND FUNCTIONAL STUDY OF SUCCINYL-ORNITHINE TRANSA FROM E. COLI ESCHERICHIA COLI TRANSFERASE PLP ENZYMES AMINOTRANSFERASE
Ref.: DETERMINATION OF THE STRUCTURE OF THE CATABOLIC N-SUCCINYLORNITHINE TRANSAMINASE (ASTC) FROM ESCHER COLI. PLOS ONE V. 8 58298 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLP SUO C:410;
A:410;
B:410;
D:410;
 Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4ADC 2.3 Å EC: 2.6.1.17 STRUCTURAL AND FUNCTIONAL STUDY OF SUCCINYL-ORNITHINE TRANSAMINASE FROM E. COLI ESCHERICHIA COLI TRANSFERASE PLP ENZYMES AMINOTRANSFERASE
Ref.: DETERMINATION OF THE STRUCTURE OF THE CATABOLIC N-SUCCINYLORNITHINE TRANSAMINASE (ASTC) FROM ESCHERIC PLOS ONE V. 8 58298 2013
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4ADD - PLP SUO n/a n/a
2 4ADC - PLP C8 H10 N O6 P Cc1c(c(c(c....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4ADD - PLP SUO n/a n/a
2 4ADC - PLP C8 H10 N O6 P Cc1c(c(c(c....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4ADD - PLP SUO n/a n/a
2 4ADC - PLP C8 H10 N O6 P Cc1c(c(c(c....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: PLP SUO; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: PLP SUO; Similar ligands found: 1
No: Ligand Similarity coefficient
1 PLP SUO 1.0000
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4ADC; Ligand: PLP; Similar sites found with APoc: 19
This union binding pocket(no: 1) in the query (biounit: 4adc.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 6JC7 F0G 26.1084
2 6JC7 F0G 26.1084
3 6JC7 F0G 26.1084
4 6JC7 F0G 26.1084
5 5KGS 6SR 35.7143
6 4ZSY RW2 40.8867
7 4ZSY RW2 40.8867
8 4ZSY RW2 40.8867
9 4ZSY RW2 40.8867
10 2OAT PFM 46.3054
11 2OAT PFM 46.3054
12 2OAT PFM 46.3054
13 2OAT PFM 46.3054
14 4UOX PUT 48.5222
15 4UOX PLP PUT 48.5222
16 1SFF IK2 49.0148
17 1SFF IK2 49.0148
18 1SFF IK2 49.0148
19 1SFF IK2 49.0148
Pocket No.: 2; Query (leader) PDB : 4ADC; Ligand: PLP; Similar sites found with APoc: 10
This union binding pocket(no: 2) in the query (biounit: 4adc.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 6JC7 F0G 26.1084
2 6JC7 F0G 26.1084
3 6JC7 F0G 26.1084
4 6JC7 F0G 26.1084
5 2OAT PFM 46.3054
6 2OAT PFM 46.3054
7 1SFF IK2 49.0148
8 1SFF IK2 49.0148
9 1SFF IK2 49.0148
10 1SFF IK2 49.0148
Pocket No.: 3; Query (leader) PDB : 4ADC; Ligand: PLP; Similar sites found with APoc: 53
This union binding pocket(no: 3) in the query (biounit: 4adc.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 6JC7 F0G 26.1084
2 6JC7 F0G 26.1084
3 6JC7 F0G 26.1084
4 4ZM4 PLP 35.468
5 4ZM4 PLP 35.468
6 4ZM4 P3B 35.468
7 4ZM4 P3B 35.468
8 4ZM4 PLP 35.468
9 4ZM4 PLP 35.468
10 4AOA IK2 37.931
11 4AOA IK2 37.931
12 4ZSY RW2 40.8867
13 4ZSY RW2 40.8867
14 2CJH AKG 40.8867
15 4B98 PXG 44.8276
16 4B98 PXG 44.8276
17 4B98 PXG 44.8276
18 4B98 PXG 44.8276
19 4E3Q PMP 45.0739
20 4E3Q PMP 45.0739
21 4E3Q PMP 45.0739
22 4E3Q PMP 45.0739
23 4E3Q PMP 45.0739
24 4E3Q PMP 45.0739
25 4E3Q PMP 45.0739
26 4E3Q PMP 45.0739
27 4UHO PLP 45.5665
28 5WYF ILP 46.0591
29 5WYF ILP 46.0591
30 5WYF ILP 46.0591
31 5WYF ILP 46.0591
32 2OAT PFM 46.3054
33 2OAT PFM 46.3054
34 5G4J EXT 46.5517
35 5G4J EXT 46.5517
36 6S4G PMP 47.0443
37 6S4G PMP 47.0443
38 6S4G PMP 47.0443
39 6S54 PLP 47.2906
40 6S54 PLP 47.2906
41 6S54 PLP 47.2906
42 6S54 PLP 47.2906
43 3A8U PLP 48.0296
44 4UOX PLP 48.5222
45 4UOX PLP 48.5222
46 4UOX PUT 48.5222
47 4UOX PLP PUT 48.5222
48 1SFF IK2 49.0148
49 1SFF IK2 49.0148
50 1SFF IK2 49.0148
51 1SFF IK2 49.0148
52 6IO1 PMP 49.2611
53 1ZC9 PMP 49.7537
54 6G4E PLP ACA 50
55 6TOR PMP 50
56 6TOR PMP 50
Pocket No.: 4; Query (leader) PDB : 4ADC; Ligand: PLP; Similar sites found with APoc: 51
This union binding pocket(no: 4) in the query (biounit: 4adc.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 6JC7 F0G 26.1084
2 6JC7 F0G 26.1084
3 6JC7 F0G 26.1084
4 5Z8A PLP JIA 30.6636
5 5Z8A PLP JIA 30.6636
6 4ZM4 PLP 35.468
7 4ZM4 P3B 35.468
8 4ZM4 PLP 35.468
9 4ZM4 PLP 35.468
10 4ZM4 P3B 35.468
11 4ZM4 PLP 35.468
12 4AOA IK2 37.931
13 4AOA IK2 37.931
14 4ZSY RW2 40.8867
15 4ZSY RW2 40.8867
16 2CJH AKG 40.8867
17 4B98 PXG 44.8276
18 4B98 PXG 44.8276
19 4B98 PXG 44.8276
20 4B98 PXG 44.8276
21 4E3Q PMP 45.0739
22 4E3Q PMP 45.0739
23 4E3Q PMP 45.0739
24 4E3Q PMP 45.0739
25 4E3Q PMP 45.0739
26 4E3Q PMP 45.0739
27 4E3Q PMP 45.0739
28 4E3Q PMP 45.0739
29 5WYF ILP 46.0591
30 5WYF ILP 46.0591
31 5WYF ILP 46.0591
32 5WYF ILP 46.0591
33 5G4J EXT 46.5517
34 5G4J EXT 46.5517
35 6S4G PMP 47.0443
36 6S4G PMP 47.0443
37 6S54 PLP 47.2906
38 6S54 PLP 47.2906
39 6S54 PLP 47.2906
40 6S54 PLP 47.2906
41 3A8U PLP 48.0296
42 4UOX PLP 48.5222
43 4UOX PLP 48.5222
44 4UOX PUT 48.5222
45 4UOX PLP PUT 48.5222
46 1SFF IK2 49.0148
47 1SFF IK2 49.0148
48 1SFF IK2 49.0148
49 1SFF IK2 49.0148
50 6IO1 PMP 49.2611
51 1ZC9 PMP 49.7537
52 6G4E PLP ACA 50
53 6TOR PMP 50
54 6TOR PMP 50
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