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Receptor
PDB id Resolution Class Description Source Keywords
4A6F 1.68 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH PHOSPHOS SACCHAROMYCES CEREVISIAE SIGNALING PROTEIN POST TRANSLATIONAL MODIFICATION
Ref.: STRUCTURAL ANALYSES OF SLM1-PH DOMAIN DEMONSTRATE L BINDING IN THE NON-CANONICAL SITE PLOS ONE V. 7 36526 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PO4 A:1583;
A:1586;
Invalid;
Invalid;
none;
none;
submit data
94.971 O4 P [O-]P...
SEP A:1584;
A:1585;
B:1584;
B:1585;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
185.072 C3 H8 N O6 P C([C@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4A6F 1.68 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH PHOSPHOS SACCHAROMYCES CEREVISIAE SIGNALING PROTEIN POST TRANSLATIONAL MODIFICATION
Ref.: STRUCTURAL ANALYSES OF SLM1-PH DOMAIN DEMONSTRATE L BINDING IN THE NON-CANONICAL SITE PLOS ONE V. 7 36526 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 4A6F - SEP C3 H8 N O6 P C([C@@H](C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 4A6F - SEP C3 H8 N O6 P C([C@@H](C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 4A6F - SEP C3 H8 N O6 P C([C@@H](C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SEP; Similar ligands found: 14
No: Ligand ECFP6 Tc MDL keys Tc
1 SEP 1 1
2 3PG 0.515152 0.74359
3 4TP 0.513514 0.833333
4 GSE 0.512195 0.833333
5 DG2 0.459459 0.675
6 DEZ 0.459459 0.707317
7 DER 0.459459 0.707317
8 RGP 0.45 0.871795
9 R10 0.425 0.707317
10 PA5 0.425 0.707317
11 PGA 0.40625 0.710526
12 OSE 0.405405 0.733333
13 LG6 0.404762 0.707317
14 6PG 0.404762 0.707317
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4A6F; Ligand: SEP; Similar sites found with APoc: 26
This union binding pocket(no: 1) in the query (biounit: 4a6f.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2BME GNP None
2 5H68 AGS None
3 1JG3 ADN None
4 1JG3 VAL TYR PRO IAS HIS ALA None
5 2HV8 GTP None
6 5H5F SAM 2.5
7 1Z06 GNP 4.16667
8 1PG4 COA 4.16667
9 1PG4 PRX 4.16667
10 4K6B GLU 5
11 6C6O ENG 5.83333
12 3EVF GTA 5.83333
13 1HDC CBO 5.83333
14 5FPE 3TR 6.66667
15 4YJI TYL 7.5
16 3OFK SAH 7.5
17 1P31 EPU 7.5
18 5OD2 5ID 7.5
19 2FH5 GTP 7.5
20 3WG6 NDP 7.5
21 1T36 U 8.33333
22 1R4A GNP 10.8333
23 1OKE BOG 10.8333
24 2AJH MET 12.5
25 3JQQ FAD 13.3333
26 1BZY IMU 19.1667
Pocket No.: 2; Query (leader) PDB : 4A6F; Ligand: SEP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4a6f.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4A6F; Ligand: SEP; Similar sites found with APoc: 1
This union binding pocket(no: 3) in the query (biounit: 4a6f.bio1) has 5 residues
No: Leader PDB Ligand Sequence Similarity
1 4J25 OGA 3.33333
Pocket No.: 4; Query (leader) PDB : 4A6F; Ligand: SEP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4a6f.bio1) has 5 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4A6F; Ligand: SEP; Similar sites found with APoc: 2
This union binding pocket(no: 5) in the query (biounit: 4a6f.bio1) has 6 residues
No: Leader PDB Ligand Sequence Similarity
1 1W5T ANP 4.16667
2 2QEN ADP 5
Pocket No.: 6; Query (leader) PDB : 4A6F; Ligand: SEP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4a6f.bio1) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 4A6F; Ligand: SEP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 4a6f.bio1) has 5 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 4A6F; Ligand: SEP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 4a6f.bio1) has 5 residues
No: Leader PDB Ligand Sequence Similarity
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