Receptor
PDB id Resolution Class Description Source Keywords
4A6D 2.4 Å EC: 2.1.1.4 CRYSTAL STRUCTURE OF HUMAN N-ACETYLSEROTONIN METHYLTRANSFERASE (ASMT) IN COMPLEX WITH SAM HOMO SAPIENS TRANSFERASE MELATONIN CIRCADIAN CLOCK
Ref.: CRYSTAL STRUCTURE AND FUNCTIONAL MAPPING OF HUMAN A LAST ENZYME OF THE MELATONIN SYNTHESIS PATHWAY. J.PINEAL RES. V. 54 46 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:1355;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SAM A:1350;
Valid;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
SO4 A:1351;
A:1352;
A:1353;
A:1354;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
ZN A:1348;
A:1349;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4A6D 2.4 Å EC: 2.1.1.4 CRYSTAL STRUCTURE OF HUMAN N-ACETYLSEROTONIN METHYLTRANSFERASE (ASMT) IN COMPLEX WITH SAM HOMO SAPIENS TRANSFERASE MELATONIN CIRCADIAN CLOCK
Ref.: CRYSTAL STRUCTURE AND FUNCTIONAL MAPPING OF HUMAN A LAST ENZYME OF THE MELATONIN SYNTHESIS PATHWAY. J.PINEAL RES. V. 54 46 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4A6D - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4A6D - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4A6D - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4A6D; Ligand: SAM; Similar sites found: 621
This union binding pocket(no: 1) in the query (biounit: 4a6d.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3R51 MMA 0.01705 0.4212 None
2 4Q3F TLA 0.01081 0.41192 None
3 3EW2 BTN 0.005157 0.40997 None
4 3H2B SAH 0.0000519 0.48885 0.985222
5 3A25 SAM 0.002921 0.41845 0.996678
6 1V6A TRE 0.001513 0.4434 1.20482
7 3RGG AIR 0.002385 0.41834 1.25786
8 4Q0A 4OA 0.000785 0.41297 1.3245
9 3DX5 DHB 0.005487 0.40419 1.3986
10 1T10 F6P 0.0125 0.40383 1.41643
11 3LZW NAP 0.001204 0.44509 1.50602
12 3LZW FAD 0.001808 0.4218 1.50602
13 1CKM GTP 0.003381 0.41737 1.51515
14 4M51 BEZ 0.0006819 0.48198 1.69972
15 2NCD ADP 0.0008906 0.45332 1.69972
16 1H16 PYR 0.003866 0.4457 1.69972
17 1GY8 NAD 0.002008 0.43791 1.69972
18 2CKM AA7 0.0008458 0.43711 1.69972
19 1DLJ NAI 0.001718 0.43345 1.69972
20 1DLJ UGA 0.001916 0.43166 1.69972
21 3K5X P8D 0.001183 0.43023 1.69972
22 3M6W SAM 0.0006083 0.42584 1.69972
23 1C7S CBS 0.001144 0.4256 1.69972
24 3A1I UNU 0.003076 0.41402 1.69972
25 1H16 DTL 0.03512 0.40526 1.69972
26 1YBH P22 0.005357 0.4046 1.69972
27 4CNK FAD 0.01743 0.40353 1.69972
28 1SB8 NAD 0.008834 0.42527 1.70455
29 1SB8 UD2 0.0103 0.42527 1.70455
30 1I0Z OXM 0.01301 0.42713 1.8018
31 2OHV NHL 0.002696 0.42134 1.89394
32 1EB9 HBA 0.0002882 0.44826 1.9084
33 2UYQ SAM 0.0000001835 0.47698 1.93548
34 2EG5 SAH 0.0000007573 0.59606 1.983
35 5HJM MTA 0.004496 0.43544 1.983
36 3V1U NAD 0.009924 0.40033 1.983
37 1QDS PGA 0.002817 0.41551 1.99203
38 1Z3C SA8 0.00008514 0.4973 2.01342
39 2VDV SAM 0.000001178 0.5872 2.03252
40 1A27 EST 0.002066 0.40687 2.07612
41 1XX6 ADP 0.005999 0.40267 2.09424
42 1DXY COI 0.0005376 0.49667 2.1021
43 1ZQ9 SAM 0.002394 0.41442 2.10526
44 3SIX GDP 0.001652 0.41955 2.12121
45 4NAO AKG 0.005107 0.43288 2.14724
46 3GJB AKG 0.0007897 0.44283 2.19436
47 1TDF NAP 0.006516 0.42403 2.21519
48 1TDF FAD 0.00631 0.40967 2.21519
49 4WVH ASP HIS ASP ALA HIS ALA 0.0004477 0.45276 2.26629
50 2Q8H TF4 0.007688 0.43865 2.26629
51 1GAD NAD 0.0004673 0.42754 2.26629
52 1D6H COA 0.002145 0.42431 2.26629
53 1BZL FAD 0.03219 0.42073 2.26629
54 4C2G ALA ALA ALA ALA 0.002906 0.42002 2.26629
55 2JC9 ADN 0.004484 0.41756 2.26629
56 3PC3 P1T 0.0005348 0.4087 2.26629
57 4GYW UDP 0.003614 0.40394 2.26629
58 3GD4 FAD 0.03816 0.4014 2.26629
59 1TUU AMP 0.0218 0.40111 2.26629
60 2AE2 NAP 0.005979 0.42684 2.30769
61 3Q3C NAD 0.001338 0.43926 2.34114
62 1Z6K OAA 0.002733 0.41361 2.38908
63 1VDC FAD 0.003887 0.4184 2.4024
64 3B1F NAD 0.0004587 0.42058 2.41379
65 2IYG FMN 0.001335 0.42306 2.41935
66 1T3D CYS 0.003872 0.43845 2.42215
67 2PZM NAD 0.0115 0.4165 2.42424
68 4DQ2 BTX 0.0009912 0.41945 2.43902
69 3CH6 311 0.03105 0.40761 2.44755
70 2YK7 CSF 0.001175 0.40307 2.45399
71 3GU3 SAH 0.0000003745 0.52163 2.46479
72 1UAY ADN 0.0001621 0.44311 2.47934
73 1YRX FMN 0.0006464 0.42489 2.47934
74 1KEW NAD 0.02769 0.40409 2.49307
75 1JN2 SFP 0.01471 0.42153 2.53165
76 3RK0 AMP 0.003784 0.40591 2.53165
77 2WA2 SAM 0.0004524 0.43795 2.53623
78 2DWU DGL 0.004761 0.41137 2.53623
79 2EFJ SAH 0.0000009608 0.54455 2.54958
80 4EUE NAI 0.0008623 0.45562 2.54958
81 4C4A SAH 0.0003186 0.45553 2.54958
82 1EDO NAP 0.0009024 0.45474 2.54958
83 2CE7 ADP 0.0002224 0.44683 2.54958
84 3TLJ SAH 0.0002563 0.43934 2.54958
85 3X0D SAH 0.0008394 0.43774 2.54958
86 3C6K SPD 0.003329 0.43422 2.54958
87 1FEC FAD 0.00818 0.426 2.54958
88 1ZBQ NAD 0.00431 0.42441 2.54958
89 4M5P 23W 0.0107 0.42435 2.54958
90 4ONQ SFG 0.001457 0.42332 2.54958
91 2WSB NAD 0.009874 0.41681 2.54958
92 2R5T ANP 0.0003187 0.41585 2.54958
93 4M5P MLA 0.03398 0.41273 2.54958
94 2C31 ADP 0.04591 0.40371 2.54958
95 2C31 TZD 0.04702 0.40371 2.54958
96 3GTD MLI 0.01379 0.40198 2.54958
97 3KLJ FAD 0.01563 0.40048 2.54958
98 1YHM AHD 0.01517 0.40019 2.54958
99 3VC1 SAH 0.0001512 0.44856 2.5641
100 3A27 SAM 0.002092 0.42471 2.57353
101 1T27 PCW 0.02145 0.40214 2.58303
102 1OC2 NAD 0.01862 0.41514 2.58621
103 1TUV VK3 0.006925 0.44093 2.63158
104 2DTX BMA 0.001725 0.45057 2.65152
105 3I0O SMI 0.003932 0.42553 2.65487
106 1U7Z PMT 0.003187 0.40712 2.65487
107 1TIW FAD 0.0006636 0.43756 2.65781
108 1TIW TFB 0.0006636 0.43756 2.65781
109 3K9W 4PS 0.02041 0.4136 2.6738
110 3K9W ADE 0.02041 0.4136 2.6738
111 1XHL NDP 0.004253 0.42467 2.6936
112 4PLG NAI 0.001059 0.42905 2.69461
113 4PLG OXM 0.001059 0.42905 2.69461
114 1P72 THM 0.006147 0.41184 2.69461
115 1AUA BOG 0.008511 0.40594 2.7027
116 1NML CIT 0.003787 0.42061 2.76074
117 4USS GSH 0.002213 0.43033 2.76923
118 1D3V ABH 0.0005638 0.42305 2.78638
119 2PT9 2MH 0.004864 0.42448 2.80374
120 2PT9 S4M 0.003312 0.4211 2.80374
121 3UH0 TSB 0.00203 0.40078 2.82609
122 2FK8 SAM 0.0009249 0.43036 2.83019
123 4KRG SAH 0.000009034 0.50723 2.83286
124 2O2C G6Q 0.002174 0.40608 2.83286
125 4LHM AZZ 0.01206 0.4045 2.83286
126 4N7C AEF 0.003011 0.44351 2.84091
127 1GSA ADP 0.0003639 0.42393 2.8481
128 1GSA GSH 0.00753 0.40232 2.8481
129 5DX8 SFG 0.01531 0.40252 2.86533
130 5DXA SFG 0.01723 0.40026 2.86533
131 3MBG FAD 0.00084 0.41716 2.8777
132 3TO7 COA 0.002468 0.41692 2.89855
133 1WRA PC 0.01986 0.40544 2.92208
134 1AE1 NAP 0.004002 0.42709 2.9304
135 2P41 SAH 0.0001874 0.45951 2.95082
136 2WCI GSH 0.009494 0.409 2.96296
137 4JLV ADP 0.03046 0.41902 2.97398
138 2J7T 274 0.0004399 0.43168 2.98013
139 3LM9 ADP 0.003839 0.40567 2.98013
140 2VQ5 LDP 0.009922 0.43307 2.98507
141 2VQ5 HBA 0.006895 0.42683 2.98507
142 1JAC AMG 0.008399 0.44486 3.00752
143 9LDT OXM 0.02319 0.42156 3.01205
144 4NEC SAH 0.000003725 0.55687 3.0303
145 3GRU AMP 0.002201 0.42552 3.05085
146 1XSE NDP 0.0149 0.40856 3.05085
147 3O03 NAP 0.002662 0.42678 3.09278
148 4TQG NDP 0.0001937 0.47988 3.09598
149 3C1O NAP 0.0013 0.40902 3.11526
150 4KRI SAH 0.000009857 0.52187 3.11615
151 4QVH FLC 0.004477 0.47098 3.11615
152 3K8L CEY 0.01119 0.42563 3.11615
153 2PUL ACP 0.0009456 0.41899 3.11615
154 2V6G NAP 0.007465 0.41251 3.11615
155 1TFZ 869 0.0007356 0.40975 3.11615
156 2F2U M77 0.004522 0.40748 3.11615
157 4DCM SAM 0.001937 0.40701 3.11615
158 2NLI LAC 0.009205 0.40598 3.11615
159 2NLI FMN 0.009205 0.40598 3.11615
160 2XVF FAD 0.01509 0.40541 3.11615
161 1Y9Q MED 0.002902 0.43746 3.125
162 2HFK E4H 0.01162 0.40029 3.1348
163 4AF5 CIT 0.001018 0.45778 3.15789
164 1A5V Y3 0.005406 0.41957 3.16456
165 1NV8 SAM 0.0008303 0.45203 3.16901
166 1NV8 MEQ 0.0007659 0.45203 3.16901
167 4CNO 9PY 0.01086 0.42198 3.1746
168 1ZK4 NAP 0.005346 0.42489 3.18725
169 1ZJ6 G3D 0.003568 0.40688 3.20856
170 1EYE PMM 0.001695 0.41913 3.21429
171 3EVF GTA 0.0006571 0.46974 3.2491
172 3EVF SAH 0.0005476 0.46974 3.2491
173 4K26 SFF 0.02039 0.40133 3.26087
174 3PMD 11A 0.006241 0.402 3.26797
175 3EVG SAH 0.0001202 0.46734 3.27273
176 3A4T SFG 0.0003821 0.45631 3.28467
177 3BHO B4P 0.02223 0.42253 3.36538
178 3OIG NAD 0.004993 0.42208 3.38346
179 1Y75 NAG 0.004147 0.41379 3.38983
180 1H5Q NAP 0.01321 0.40144 3.39623
181 1UWK URO 0.002112 0.45257 3.39943
182 3L9W AMP 0.001292 0.44641 3.39943
183 2ZWS PLM 0.01442 0.44111 3.39943
184 2IZ1 ATR 0.005483 0.42512 3.39943
185 3L9W GSH 0.004172 0.4211 3.39943
186 3MD0 GDP 0.006049 0.40717 3.39943
187 2IMP NAI 0.02169 0.40648 3.39943
188 4IHQ ADP 0.006714 0.40534 3.39943
189 1PEA ACM 0.02824 0.40388 3.39943
190 3UER BTU 0.005269 0.40045 3.39943
191 3UER TUR 0.005269 0.40045 3.39943
192 4BMO FMN 0.0005302 0.42396 3.41615
193 3UEC ALA ARG TPO LYS 0.001418 0.45867 3.42466
194 4EXO PYR 0.01321 0.41992 3.42466
195 1H2K OGA 0.004573 0.42864 3.4384
196 2WA4 069 0.001313 0.42333 3.4384
197 3P3N AKG 0.00734 0.41945 3.4384
198 3RF4 FUN 0.001993 0.43223 3.44828
199 4F8L GAL 0.0293 0.42398 3.44828
200 4W6Z ETF 0.004128 0.45223 3.45821
201 4BLW AMP 0.01088 0.40869 3.46021
202 4BLW SAH 0.008848 0.4025 3.46021
203 1L1E SAH 0.0006975 0.44317 3.48432
204 3OID NDP 0.004469 0.42494 3.48837
205 4NBW NAD 0.007641 0.40813 3.50195
206 2C7G FAD 0.003248 0.42704 3.50877
207 2C7G ODP 0.01155 0.40525 3.50877
208 4HZD COA 0.00526 0.40174 3.5461
209 2BZ1 TAU 0.0006183 0.51651 3.57143
210 4R33 TRP 0.00221 0.41276 3.57143
211 4R33 SAH 0.00221 0.41276 3.57143
212 2Q8M AMP 0.001517 0.42095 3.61446
213 2OWZ CIT 0.01304 0.40827 3.61446
214 1C1L GAL BGC 0.001652 0.4556 3.64964
215 4B9E FAH 0.003905 0.43829 3.65448
216 1BXK NAD 0.009363 0.40558 3.66197
217 2XVE FAD 0.03041 0.40744 3.66379
218 1ECM TSA 0.004725 0.4115 3.66972
219 4DMG SAM 0.0004694 0.47249 3.68272
220 4N49 SAM 0.0006113 0.44561 3.68272
221 2BO4 FLC 0.00322 0.44217 3.68272
222 2YVF NAD 0.002152 0.43762 3.68272
223 2YVF FAD 0.002215 0.43641 3.68272
224 1T26 GBD 0.006056 0.43478 3.68272
225 1T26 NAI 0.006056 0.43478 3.68272
226 1RYI GOA 0.02539 0.42926 3.68272
227 2EJU SAH 0.001072 0.42769 3.68272
228 1V5F TPP 0.03697 0.41566 3.68272
229 1Q3Q ANP 0.00828 0.41077 3.68272
230 2NVK NAP 0.006657 0.41039 3.68272
231 2YP9 SIA CMO 0.001937 0.40575 3.68272
232 1V5F FAD 0.04065 0.40305 3.68272
233 3EYA FAD 0.01584 0.40239 3.68272
234 3B96 MYA 0.001344 0.40115 3.68272
235 2QLX RM4 0.001586 0.45641 3.7037
236 2PXX SAH 0.00007893 0.48115 3.72093
237 1KYV RBF 0.001382 0.40878 3.77358
238 1G55 SAH 0.0001931 0.46473 3.79009
239 3K3K A8S 0.0004607 0.41643 3.79147
240 1QJC PNS 0.00795 0.41033 3.79747
241 2XI7 XI7 0.00132 0.49839 3.80435
242 1ZEM NAD 0.003504 0.42156 3.81679
243 2FWP ICR 0.00161 0.42013 3.82514
244 1U7T TDT 0.00208 0.44896 3.83142
245 1TPY SAH 0.0006888 0.44536 3.83275
246 1Z42 HBA 0.002258 0.49043 3.84615
247 1Z48 FMN 0.002149 0.40625 3.84615
248 3PMA SCR 0.009756 0.40346 3.861
249 2YX1 SFG 0.0001482 0.44459 3.86905
250 3EGI ADP 0.00006034 0.53608 3.8835
251 3CQD ATP 0.006509 0.40061 3.8835
252 1EJ0 SAM 0.00004012 0.48718 3.88889
253 1XTP SAI 0.00003825 0.48843 3.93701
254 2F01 BTQ 0.008102 0.41726 3.93701
255 2F01 BTN 0.008102 0.41726 3.93701
256 1XE7 GUN 0.002245 0.46552 3.94089
257 5KOK SAH 0.001238 0.4614 3.96601
258 1T0S BML 0.00214 0.45808 3.96601
259 1DL5 SAH 0.0006391 0.45386 3.96601
260 2W8Q SIN 0.002753 0.44532 3.96601
261 3WE0 FAD 0.0007434 0.44129 3.96601
262 4OYA 1VE 0.008449 0.43068 3.96601
263 2YIV YIV 0.008299 0.42969 3.96601
264 1GJW MAL 0.001991 0.42141 3.96601
265 1E5F PLP 0.0009345 0.41918 3.96601
266 1X87 NAD 0.003095 0.41914 3.96601
267 3VSE SAH 0.000647 0.41571 3.96601
268 1GJW GLC 0.01668 0.40898 3.96601
269 2YIV NBN 0.01806 0.40736 3.96601
270 1D09 PAL 0.04973 0.40102 3.96601
271 3NNF AKG 0.00318 0.43569 4.06977
272 4M37 SAH 0.001743 0.4243 4.08163
273 4M38 SAH 0.001641 0.41951 4.08163
274 1WGC SIA GAL BGC 0.03248 0.41378 4.09357
275 1QAN SAH 0.001698 0.42859 4.09836
276 1UDB NAD 0.01068 0.42377 4.14201
277 1KPH SAH 0.0008993 0.4404 4.18118
278 1KPG SAH 0.0008577 0.4264 4.18118
279 4TMK T5A 0.001784 0.41475 4.22535
280 4E13 NAD 0.0009413 0.40031 4.24028
281 2WPF FAD 0.02491 0.42599 4.24242
282 2WPF WPF 0.03399 0.42033 4.24242
283 4WBD CIT 0.001019 0.47359 4.24929
284 1SQF SAM 0.0009079 0.43097 4.24929
285 4LIT AKG 0.003223 0.42925 4.24929
286 2ZJ5 ADP 0.009686 0.40862 4.24929
287 4WBD ADP 0.02053 0.40477 4.24929
288 1A59 CIT 0.0241 0.4015 4.24929
289 4DEC UDP 0.0001404 0.40014 4.24929
290 4DEC 3PG 0.0001404 0.40014 4.24929
291 2Y7G AAE 0.0002831 0.4377 4.25532
292 3W54 RNB 0.0008982 0.42455 4.25532
293 3SQG COM 0.01272 0.43535 4.30108
294 1ORR NAD 0.0004029 0.47178 4.32277
295 3PA8 621 0.0156 0.41281 4.33071
296 1WY7 SAH 0.0006489 0.44647 4.34783
297 5FA8 SAM 0.002586 0.43648 4.34783
298 1R6W 164 0.002328 0.40502 4.34783
299 1PX8 XYP 0.000436 0.46667 4.4
300 1YOA FMN 0.004248 0.47042 4.40252
301 2Q37 3AL 0.006646 0.4157 4.41989
302 1LYX PGA 0.0008848 0.42479 4.43548
303 1BC5 SAH 0.001069 0.43902 4.46097
304 2ZWA SAH 0.00001664 0.51455 4.53258
305 1JQ5 NAD 0.004799 0.44975 4.53258
306 1G60 SAM 0.001288 0.42987 4.53258
307 2HGS ADP 0.0003833 0.42318 4.53258
308 1RYD GLC 0.006807 0.42092 4.53258
309 1V59 FAD 0.01538 0.41232 4.53258
310 3PLN U5P 0.009427 0.40408 4.53258
311 2QQF A1R 0.0003538 0.42995 4.54545
312 1DL7 NCH 0.005546 0.46404 4.58716
313 3LCV SAM 0.00001543 0.51821 4.62633
314 1Q0S SAH 0.0008219 0.44571 4.6332
315 2VDJ HSE 0.01163 0.4226 4.65116
316 2XK9 XK9 0.002602 0.41148 4.65839
317 3ELW SAM 0.0003482 0.48468 4.66667
318 3ELW GP3 0.0003988 0.48308 4.66667
319 1C0I FAD 0.002951 0.42108 4.6832
320 1C0I BE2 0.002951 0.42108 4.6832
321 1E6E FAD 0.01812 0.40077 4.6875
322 2ZIF SAM 0.001581 0.4261 4.7138
323 3FRH SAH 0.00000098 0.56971 4.74308
324 2Q46 NAP 0.007789 0.40912 4.74308
325 1JQD HSM 0.0003004 0.41719 4.79452
326 1JQD SAH 0.0002973 0.40719 4.79452
327 3FUU ADN 0.0007936 0.43876 4.79705
328 4FZV SAM 0.0007672 0.44142 4.81586
329 1I2B NAD 0.007675 0.43283 4.81586
330 2ZJF BSU 0.001848 0.42266 4.81586
331 1ZED PNP 0.009648 0.42005 4.81586
332 1I2B UPG 0.00534 0.41804 4.81586
333 1I2B USQ 0.00534 0.41804 4.81586
334 3QV9 QV7 0.007136 0.41436 4.81586
335 3WO0 ADP 0.003922 0.40744 4.81586
336 3WO0 ALA 0.003922 0.40744 4.81586
337 3ICS FAD 0.01469 0.40693 4.81586
338 3ICR FAD 0.01785 0.40206 4.81586
339 4RJK PYR 0.03184 0.40134 4.81586
340 2GDZ NAD 0.01258 0.40116 4.81586
341 5ULP KB1 0.01276 0.40345 4.85075
342 3P2E SAH 0.0001653 0.46978 4.88889
343 3QDT A2G GAL 0.0002249 0.50517 4.8951
344 3QDY A2G GAL 0.0002431 0.50354 4.8951
345 3QDY CBS 0.01033 0.41868 4.8951
346 1C3V PDC 0.008871 0.41027 4.89796
347 3QP4 HL0 0.001018 0.41785 4.94506
348 3LKZ SFG 0.0002743 0.45828 4.98442
349 3FZG SAM 0.00004548 0.50784 5
350 1LSS NAD 0.0005615 0.44718 5
351 1FIQ FAD 0.0006008 0.43411 5.02283
352 1FIQ MTE 0.0005115 0.43094 5.02283
353 1FIQ SAL 0.000619 0.43094 5.02283
354 1R6D NAD 0.01723 0.41536 5.04451
355 1R6D DAU 0.01874 0.4129 5.04451
356 1RJD SAM 0.000002252 0.54914 5.08982
357 3MB5 SAM 0.0002701 0.46473 5.09804
358 3Q9T FAY 0.00001398 0.49818 5.09915
359 2XDQ MGX 0.01384 0.42577 5.09915
360 5JJR SAH 0.01619 0.41254 5.09915
361 3SSO SAH 0.003915 0.41128 5.09915
362 1AX2 NDG GAL 0.007886 0.40732 5.09915
363 1EU1 MGD 0.01575 0.40455 5.09915
364 1RSG FAD 0.02414 0.40062 5.09915
365 1B74 DGN 0.003483 0.44788 5.11811
366 2AOT SAH 0.00009585 0.45884 5.13699
367 1U5R ATP 0.0008597 0.42047 5.17241
368 2PX8 SAH 0.001313 0.42351 5.20446
369 2JAH NDP 0.007338 0.41284 5.26316
370 3ZV6 NAD 0.004388 0.43402 5.33808
371 3ZV6 4HB 0.004605 0.43402 5.33808
372 1GU3 BGC BGC BGC BGC BGC 0.009341 0.40425 5.36913
373 3NDJ SAH 0.0007208 0.47529 5.38244
374 1I8T FAD 0.005151 0.42881 5.38244
375 3DMH SAM 0.001227 0.42417 5.38244
376 3CL7 HYN 0.002331 0.40044 5.38244
377 2BGM NAJ 0.004995 0.41482 5.39568
378 1Y1A GSH 0.007618 0.45991 5.46448
379 2JFV FLC 0.01512 0.40538 5.49828
380 3MQ2 SAH 0.0002123 0.45304 5.50459
381 4LWM MHO 0.01357 0.44204 5.52995
382 3MAG 3MA 0.02768 0.41747 5.53746
383 3SJ7 NDP 0.002776 0.42891 5.55556
384 2HMT NAI 0.003856 0.41333 5.55556
385 4PIO SAH 0.000005737 0.55616 5.57276
386 4PIO AVI 0.000005346 0.55586 5.57276
387 3DAG FEG 0.0008937 0.41624 5.58659
388 3SJ0 DXC 0.01093 0.41752 5.6338
389 3GM5 CIT 0.003219 0.43545 5.66038
390 2IV2 MGD 0.004307 0.42915 5.66572
391 3L24 GOA 0.02007 0.41761 5.66572
392 1JIL 485 0.001073 0.40437 5.66572
393 3GCZ SAM 0.00007363 0.47619 5.67376
394 2QCX PF1 0.01381 0.40196 5.70342
395 4CQM NAP 0.01004 0.40553 5.7377
396 3TKA CTN 0.001534 0.4926 5.76369
397 3TKA SAM 0.005385 0.40537 5.76369
398 3HVJ 705 0.001398 0.45248 5.88235
399 4HXY NDP 0.003802 0.42557 5.93607
400 1UF5 CDT 0.001838 0.42276 5.94059
401 1F3L SAH 0.0001168 0.47833 5.94901
402 2JJQ SAH 0.002869 0.43083 5.94901
403 2QF7 COA 0.00157 0.41562 5.94901
404 1YS4 NAP 0.000693 0.4146 5.94901
405 2AMV BIN 0.008003 0.40828 5.94901
406 1NW5 SAM 0.00189 0.42282 5.95611
407 3LCC SAH 0.000001277 0.54124 5.95745
408 2EB5 OXL 0.0008447 0.46139 5.99251
409 3CEV ARG 0.007594 0.40318 6.02007
410 1JNR FAD 0.01276 0.43286 6.06532
411 1I9G SAM 0.002731 0.41794 6.07143
412 4JEJ 1GP 0.002632 0.41188 6.14754
413 3H8V ATP 0.0008387 0.43302 6.16438
414 1OAA OAA 0.001471 0.43035 6.17761
415 2DTJ THR 0.006254 0.40197 6.17978
416 1KTC NGA 0.00452 0.41741 6.23229
417 3F3E LEU 0.003754 0.40924 6.23229
418 2BRY FAD 0.01583 0.40023 6.23229
419 2OFE NAG 0.005328 0.42568 6.33803
420 3FPZ AHZ 0.009246 0.42135 6.44172
421 2YBQ UP2 0.0003833 0.44369 6.50685
422 4GQB 0XU 0.0000361 0.50442 6.51558
423 4AZW SAM 0.0002593 0.45931 6.51558
424 4AZT SAM 0.000202 0.45872 6.51558
425 3GE7 AFQ 0.0005977 0.43285 6.51558
426 3ZGE ASP 0.007766 0.43108 6.51558
427 5FA5 MTA 0.009517 0.4303 6.51558
428 4C0C WVH 0.001631 0.42968 6.51558
429 1UOU CMU 0.0009155 0.42424 6.51558
430 3O2K DST 0.003668 0.42119 6.51558
431 2GWD GLU 0.002996 0.41949 6.51558
432 3G5S FAD 0.008739 0.41625 6.51558
433 2Q28 ADP 0.00422 0.40805 6.51558
434 3O2K QRP 0.005889 0.40299 6.51558
435 1P1C SAH 0.008298 0.40067 6.53266
436 3T2W BTN 0.005351 0.40462 6.55738
437 4KOA NDP 0.001129 0.41183 6.60661
438 1QO0 BMD 0.0158 0.40453 6.63265
439 3L6R MLI 0.01208 0.41551 6.6474
440 3WCS MAN NAG GAL 0.003457 0.41204 6.69291
441 3WCS MAN NAG 0.008923 0.40508 6.69291
442 1E4E PHY 0.002383 0.40465 6.70554
443 1POC GEL 0.0001389 0.44342 6.71642
444 4U9W COA 0.001537 0.40718 6.76329
445 4B16 NAG 0.03069 0.41509 6.76692
446 3U1T MLI 0.01779 0.40767 6.79612
447 3W8S GSH 0.01313 0.40291 6.79612
448 3MTW M3R 0.001298 0.41408 6.79887
449 3LAD FAD 0.01573 0.40929 6.79887
450 4G1V FAD 0.002365 0.4034 6.79887
451 1NM5 NAP 0.03261 0.40068 6.79887
452 1SC3 MLI 0.03057 0.4022 6.81818
453 5D63 FUC GLA GLA 0.003823 0.43212 6.82594
454 5D63 FUC GAL GLA 0.004221 0.41348 6.82594
455 1MXI SAH 0.000966 0.40993 6.875
456 4COQ SAN 0.002751 0.43851 6.88259
457 3NUG NAD 0.01265 0.40227 6.88259
458 1TH8 ADP 0.002356 0.41854 6.89655
459 3JWH SAH 0.000002418 0.50295 6.91244
460 3KO0 TFP 0.03907 0.42125 6.93069
461 1G8S MET 0.008752 0.41603 6.95652
462 4GO7 THR 0.006644 0.40094 7
463 2BNE U5P 0.004726 0.40166 7.05394
464 3PT9 SAH 0.001305 0.42444 7.08215
465 4IOK ADP 0.001628 0.40896 7.08215
466 4IOK XPO 0.001447 0.40573 7.08215
467 3U4C NDP 0.0001621 0.48329 7.11744
468 1O9U ADZ 0.000639 0.49291 7.14286
469 2A14 SAH 0.001272 0.43396 7.22433
470 1JGS SAL 0.004837 0.46731 7.24638
471 1I1Q TRP 0.00838 0.40145 7.29167
472 3H86 AP5 0.01439 0.40051 7.29167
473 3BGD PM6 0.00007014 0.49758 7.30769
474 3BGD SAH 0.00007547 0.48855 7.30769
475 4LWP SAH 0.0003868 0.44685 7.33696
476 2PWY SAH 0.0006704 0.44774 7.36434
477 1NN5 ANP 0.0003236 0.43787 7.44186
478 1NN5 2DT 0.0003236 0.43787 7.44186
479 1R37 NAD 0.01336 0.40467 7.4928
480 2OBF F83 0.001721 0.45377 7.61246
481 4HA6 PXM 0.002191 0.43648 7.64873
482 1XKQ NDP 0.002946 0.43306 7.64873
483 4JHG ZEA 0.002531 0.40372 7.7381
484 1F1V DHY 0.00293 0.41988 7.73994
485 2BZG SAH 0.0001531 0.46345 7.75862
486 3CF6 SP1 0.000817 0.42126 7.78443
487 1Q11 TYE 0.003152 0.42394 7.7957
488 3DXY SAM 0.000008753 0.55424 7.79817
489 3T7S SAM 0.00001183 0.50927 7.83582
490 1SS4 GSH 0.0003188 0.54274 7.84314
491 1B5E DCM 0.0007483 0.44377 7.93201
492 2V7T SAH 0.02332 0.40903 8.02676
493 3FPF MTA 0.000558 0.47299 8.05369
494 4G28 0W8 0.008124 0.402 8.05369
495 5MDH NAD 0.009563 0.40384 8.10811
496 4QTU SAM 0.000008063 0.52305 8.17308
497 1G0N NDP 0.004612 0.42997 8.2153
498 1G0N PHH 0.005734 0.42866 8.2153
499 4KCF AKM 0.003594 0.42138 8.2153
500 1TMO 2MD 0.009921 0.41374 8.2153
501 4INB 1F6 0.0009679 0.40584 8.21918
502 2YY7 NAD 0.007512 0.41239 8.33333
503 3G2O SAM 0.00006681 0.48932 8.3612
504 3BXO SAM 0.00001244 0.48674 8.3682
505 1H8G CHT 0.01443 0.44108 8.42105
506 3G89 SAM 0.000001507 0.58226 8.43373
507 1Y2W NAG 0.006654 0.42136 8.4507
508 2WET FAD 0.01477 0.40966 8.49858
509 3E81 SLB 0.005082 0.42072 8.53659
510 3PFG SAM 0.000000198 0.56835 8.78187
511 3PFG TLO 0.0001765 0.49707 8.78187
512 3DG6 MUC 0.001126 0.42093 8.78187
513 1NJR XYL 0.007218 0.40922 8.78187
514 3DCM SAM 0.000177 0.43009 8.85417
515 2XVM SAH 0.00002377 0.47649 9.04523
516 1RZM E4P 0.001231 0.46151 9.06516
517 2Z9V PXM 0.002525 0.42795 9.06516
518 3PNA CMP 0.003189 0.4184 9.09091
519 1WG8 SAM 0.0008752 0.44453 9.12281
520 1JA9 NDP 0.002685 0.43359 9.12409
521 4II2 ATP 0.001302 0.43164 9.20245
522 2YYJ FAD 0.032 0.40063 9.34844
523 2YYJ 4HP 0.032 0.40063 9.34844
524 1YGC 905 0.0009562 0.40601 9.52381
525 3WUD GLC GAL 0.02932 0.40309 9.55882
526 5MPT SAH 0.008552 0.42569 9.63173
527 2HQM FAD 0.02011 0.40432 9.63173
528 1Y42 TYR 0.008191 0.40663 9.91501
529 1X8X TYR 0.005544 0.40402 9.93789
530 3GDH SAH 0.00003092 0.46509 9.95851
531 1N2X SAM 0.002109 0.42632 9.96678
532 2X61 CH 0.00145 0.42639 10.0775
533 2X61 NGA GAL SIA 0.01478 0.40253 10.0775
534 1N9L FMN 0.0000583 0.4511 10.0917
535 2B7N NTM 0.007018 0.41467 10.2564
536 2V2V V12 0.005968 0.42785 10.7011
537 4JCA CIT 0.01315 0.4346 10.7784
538 2DVZ GLU 0.00679 0.40057 10.828
539 2V5E SCR 0.009644 0.4417 10.8911
540 1O97 AMP 0.01692 0.41714 10.9375
541 1TUF AZ1 0.0004623 0.42422 11.0482
542 4AMV F6R 0.002645 0.40303 11.0482
543 3F8C HT1 0.01381 0.40196 11.1111
544 4EMJ FAD 0.01647 0.40562 11.215
545 3AD8 FAD 0.04209 0.40344 11.33
546 4CCN OGA 0.004412 0.42934 11.4286
547 3O7W SAM 0.00000009034 0.56434 11.5646
548 1ZFJ IMP 0.02962 0.40734 11.6147
549 2FR6 CTN 0.0008656 0.41153 11.6438
550 4GKV NAD 0.01544 0.40182 11.9048
551 1JG3 ADN 0.0006525 0.44658 11.9149
552 4OBW SAM 0.0003222 0.45981 12.0623
553 3QOX SAH 0.00009086 0.48508 12.1813
554 1IY8 NAD 0.004918 0.42059 12.3596
555 3OU2 SAH 0.00002314 0.46428 12.3853
556 5GM1 SAH 0.006975 0.41756 12.4579
557 5THY SAH 0.01219 0.41239 12.4646
558 3VYW SAM 0.004835 0.40039 12.6623
559 1EYQ NAR 0.006098 0.40703 13.0631
560 3SCH TB6 0.0009159 0.45982 13.1313
561 1ZZ7 S0H 0.0005016 0.45717 13.1313
562 4F4S EFO 0.003364 0.42276 13.1579
563 1R18 SAH 0.0006305 0.447 13.2159
564 2DPM SAM 0.0005356 0.45004 13.3803
565 5FTW SAH 0.00446 0.4323 13.6719
566 2JBH 5GP 0.0007601 0.4435 13.881
567 1PTR PRB 0.003811 0.43878 14
568 2GJ3 FAD 0.002918 0.40525 14.1667
569 1SQ5 PAU 0.007363 0.40857 14.2857
570 1U2Z SAH 0.0003348 0.46071 14.4476
571 2W3L DRO 0.02076 0.41687 14.5833
572 3QWI NAP 0.003608 0.42786 14.8148
573 3QWI CUE 0.005966 0.42786 14.8148
574 2ZFU SAH 0.00002262 0.50652 14.8837
575 4DSG UDP 0.03269 0.40591 15.5807
576 2HNK SAH 0.00468 0.40797 15.8996
577 1ULE GLA GAL NAG 0.02061 0.41055 16
578 1Q3P GLU ALA GLN THR ARG LEU 0.003778 0.41543 16.5138
579 3GEG NAD 0.0004114 0.46387 16.5992
580 1NF8 ISC 0.002794 0.4109 17.3913
581 3F81 STT 0.003209 0.45773 17.4863
582 3EGV SAH 0.001762 0.43195 17.7165
583 2NXE SAM 0.001521 0.4307 17.7165
584 3S9K CIT 0.0004779 0.52159 17.7966
585 2YLD CMO 0.01263 0.40889 18.1102
586 2VPY MGD 0.01913 0.41908 18.1818
587 2H6B 3C4 0.004072 0.42253 18.4136
588 1NU4 MLA 0.008672 0.45332 18.5567
589 1I1N SAH 0.0001425 0.48408 18.5841
590 5MGZ SAH 0.00306 0.44319 18.6441
591 5E1M SAH 0.003028 0.43995 18.6722
592 1IM8 SAI 0.00006213 0.4776 19.6721
593 4R6W PC 0.00007517 0.5263 20.155
594 4R6W SAH 0.00003513 0.51765 20.155
595 3Q87 SAM 0.003728 0.41566 20.5882
596 1FP2 SAH 5.482e-16 0.87339 20.7386
597 4E70 N7I 0.00000000103 0.57482 21.2465
598 3I53 SAH 0.0000000001207 0.73082 21.3855
599 5F8F SFG 0.001128 0.47588 21.813
600 4K30 NLG 0.007771 0.40759 21.875
601 1H2M OGA 0.005238 0.42601 23.0769
602 1L3I SAH 0.0004714 0.45963 23.9583
603 4IWN GEK 0.00001831 0.51501 24.0175
604 1VE3 SAM 0.000005637 0.52282 24.2291
605 4M73 M72 0.00003857 0.52333 26.3456
606 3OFK SAH 0.003574 0.40194 27.7778
607 1XDS SAM 0.000000000164 0.76522 28.3286
608 1QZZ SAM 0.0000000008236 0.64967 28.8952
609 4KIB SAH 0.000005859 0.51453 28.8952
610 1UO5 PIH 0.002684 0.48141 29.4118
611 1UO4 PIH 0.01047 0.43982 29.4118
612 5E8J SAH 0.00106 0.48187 34.0909
613 3GXO SAH 0.0000000003112 0.74086 38.5269
614 3GWZ SAH 0.00000000003263 0.69515 38.5269
615 3LST SAH 0.0000000002619 0.75583 39.3678
616 3P9C SAH 0.0000000004356 0.73656 40.5099
617 1FP1 SAH 0.00000000001008 0.72507 40.7932
618 1ZGA SAH 0.000000001045 0.637 41.3598
619 1KYZ FER 0.000000005118 0.67907 42.2096
620 1KYZ SAH 0.000000001228 0.67298 42.2096
621 3TKY SAH 0.000000000001643 0.80595 43.9093
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