Receptor
PDB id Resolution Class Description Source Keywords
3zrl 2.48 Å EC: 2.7.11.26 IDENTIFICATION OF 2-(4-PYRIDYL)THIENOPYRIDINONES AS GSK-3BET INHIBITORS HOMO SAPIENS TRANSFERASE-PEPTIDE COMPLEX KINASE
Ref.: IDENTIFICATION OF 2-(4-PYRIDYL)THIENOPYRIDINONES AS GSK-3BETA INHIBITORS. BIOORG.MED.CHEM.LETT. V. 21 4823 2011
Ligand Information
Ligand Validity Binding Data Ligand Warnings Chemaxon Viewer Molecular Weight (Da) Formula SMILES
GOL Invalid - none 92.094
C3 H8 O3
C(C(CO)O)O
SO4 Invalid - none 96.063
O4 S
[O-]S(=O)(=O)[O-]
ZRL Valid ic50 = 0.16 uM none 307.166
C12 H7 Br N2 O S
c1cnccc1c2cc3c(s2)C(=CNC3=O)Br
90% Homology Family

The Class containing this family consists of a total of 3 families.

Leader:    3ZRM     IDENTIFICATION OF 2-(4-PYRIDYL)THIENOPYRIDINONES AS GSK- 3BETA INHIBITORS
No: PDB id Binding Data Representative ligand
1 3ZRL ic50 = 0.16 uM ZRL
2 3ZRM ic50 = 0.13 uM ZRM
3 4AFJ ic50 = 0.4 uM SJJ
4 3ZRK ic50 = 0.13 uM ZRK
More Information
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