Receptor
PDB id Resolution Class Description Source Keywords
3zrl 2.48 Å EC: 2.7.11.26 IDENTIFICATION OF 2-(4-PYRIDYL)THIENOPYRIDINONES AS GSK-3BET INHIBITORS HOMO SAPIENS TRANSFERASE-PEPTIDE COMPLEX KINASE
Ref.: IDENTIFICATION OF 2-(4-PYRIDYL)THIENOPYRIDINONES AS GSK-3BETA INHIBITORS. BIOORG.MED.CHEM.LETT. V. 21 4823 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data Chemaxon Viewer Molecular Weight (Da) Formula SMILES
GOL A:1389;
B:1388;
B:1389;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data 92.094 C3 H8 O3 C(C(C...
SO4 A:1386;
A:1387;
A:1388;
B:1385;
B:1386;
B:1387;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data 96.063 O4 S [O-]S...
ZRL A:1390;
B:1390;
Valid;
Valid;
none;
none;
ic50 = 0.16 uM 307.166 C12 H7 Br N2 O S c1cnc...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3ZRM 2.49 Å EC: 2.7.11.26 IDENTIFICATION OF 2-(4-PYRIDYL)THIENOPYRIDINONES AS GSK- 3BETA INHIBITORS HOMO SAPIENS TRANSFERASE-PEPTIDE COMPLEX KINASE
Ref.: IDENTIFICATION OF 2-(4-PYRIDYL)THIENOPYRIDINONES AS GSK-3BETA INHIBITORS. BIOORG.MED.CHEM.LETT. V. 21 4823 2011
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3ZRL ic50 = 0.16 uM ZRL C12 H7 Br N2 O S c1cnccc1c2....
2 3ZRM ic50 = 0.13 uM ZRM C18 H12 N2 O2 S c1cc(ccc1C....
3 4AFJ ic50 = 0.4 uM SJJ C17 H15 N3 O3 COc1ccc(cc....
4 3ZRK ic50 = 0.13 uM ZRK C12 H8 N2 O2 c1cnccc1c2....