Receptor
PDB id Resolution Class Description Source Keywords
3ujs 1.65 Å EC: 4.2.1.11 ASYMMETRIC COMPLEX OF HUMAN NEURON SPECIFIC ENOLASE-6-PGA/PE HOMO SAPIENS LYASE
Ref.: STRUCTURES OF ASYMMETRIC COMPLEXES OF HUMAN NEURON ENOLASE WITH RESOLVED SUBSTRATE AND PRODUCT AND AN COMPLEX WITH TWO INHIBITORS INDICATE SUBUNIT INTERA INHIBITOR COOPERATIVITY. J.INORG.BIOCHEM. V. 111 187 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
0V5 B:602;
 Valid;
 none;
 Ki = 0.4 mM
170.058 C3 H7 O6 P C[C@H...
MG A:600;
A:601;
B:600;
B:601;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
 submit data
24.305 Mg [Mg+2...
TRS A:603;
 Invalid;
 none;
 submit data
122.143 C4 H12 N O3 C(C(C...
XSP A:602;
 Valid;
 none;
 Ki = 0.004 mM
184.041 C3 H5 O7 P C(=O)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4ZCW 1.99 Å EC: 4.2.1.11 STRUCTURE OF HUMAN ENOLASE 2 IN COMPLEX WITH SF2312 HOMO SAPIENS ENOLASE GAMMA GLYCOLYSIS NEURON SPECIFIC ENOLASE INHIBITOLYASE INHIBITOR COMPLEX
Ref.: SF2312 IS A NATURAL PHOSPHONATE INHIBITOR OF ENOLAS NAT.CHEM.BIOL. V. 12 1053 2016
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 3UJF - PEP C3 H5 O6 P C=C(C(=O)O....
2 4ZA0 - PAH C2 H6 N O5 P C(C(=O)NO)....
3 3UCD - PEP C3 H5 O6 P C=C(C(=O)O....
4 3UCC - 2PG C3 H7 O7 P C([C@H](C(....
5 4ZCW ic50 = 42.5 nM 4NG C4 H8 N O6 P C1[C@@H](C....
6 3UJE - PEP C3 H5 O6 P C=C(C(=O)O....
7 3UJS Ki = 0.4 mM 0V5 C3 H7 O6 P C[C@H](C(=....
8 3UJR - PEP C3 H5 O6 P C=C(C(=O)O....
70% Homology Family (33)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3UJF - PEP C3 H5 O6 P C=C(C(=O)O....
2 4ZA0 - PAH C2 H6 N O5 P C(C(=O)NO)....
3 3UCD - PEP C3 H5 O6 P C=C(C(=O)O....
4 3UCC - 2PG C3 H7 O7 P C([C@H](C(....
5 4ZCW ic50 = 42.5 nM 4NG C4 H8 N O6 P C1[C@@H](C....
6 3UJE - PEP C3 H5 O6 P C=C(C(=O)O....
7 3UJS Ki = 0.4 mM 0V5 C3 H7 O6 P C[C@H](C(=....
8 3UJR - PEP C3 H5 O6 P C=C(C(=O)O....
9 6D3Q Ki = 3.4 nM 4NG C4 H8 N O6 P C1[C@@H](C....
10 5ENL - 2PG C3 H7 O7 P C([C@H](C(....
11 2AL1 - PEP C3 H5 O6 P C=C(C(=O)O....
12 1ONE - PEP C3 H5 O6 P C=C(C(=O)O....
13 2XH2 - 2PG C3 H7 O7 P C([C@H](C(....
14 2XH4 - 2PG C3 H7 O7 P C([C@H](C(....
15 1L8P - PAH C2 H6 N O5 P C(C(=O)NO)....
16 1ELS Ki = 15 pM PAH C2 H6 N O5 P C(C(=O)NO)....
17 6ENL - PGA C2 H5 O6 P C(C(=O)O)O....
18 1EBG Ki = 15 pM PAH C2 H6 N O5 P C(C(=O)NO)....
19 1P48 - PEP C3 H5 O6 P C=C(C(=O)O....
20 2ONE - PEP C3 H5 O6 P C=C(C(=O)O....
21 2XH7 - 2PG C3 H7 O7 P C([C@H](C(....
22 2XH0 - PEP C3 H5 O6 P C=C(C(=O)O....
23 2XGZ - PEP C3 H5 O6 P C=C(C(=O)O....
24 7ENL - 2PG C3 H7 O7 P C([C@H](C(....
25 1P43 - 2PG C3 H7 O7 P C([C@H](C(....
26 4A3R Ki = 5 mM CIT C6 H8 O7 C(C(=O)O)C....
27 5BOE - PEP C3 H5 O6 P C=C(C(=O)O....
28 3QTP - 2PG C3 H7 O7 P C([C@H](C(....
29 2PTZ - PAH C2 H6 N O5 P C(C(=O)NO)....
30 2PU1 - FSG C2 H5 F N O5 P [C@H](C(=O....
31 2PTY - PEP C3 H5 O6 P C=C(C(=O)O....
32 2PU0 - PAH C2 H6 N O5 P C(C(=O)NO)....
33 1PDZ Ki = 0.2 mM PGA C2 H5 O6 P C(C(=O)O)O....
50% Homology Family (33)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3UJF - PEP C3 H5 O6 P C=C(C(=O)O....
2 4ZA0 - PAH C2 H6 N O5 P C(C(=O)NO)....
3 3UCD - PEP C3 H5 O6 P C=C(C(=O)O....
4 3UCC - 2PG C3 H7 O7 P C([C@H](C(....
5 4ZCW ic50 = 42.5 nM 4NG C4 H8 N O6 P C1[C@@H](C....
6 3UJE - PEP C3 H5 O6 P C=C(C(=O)O....
7 3UJS Ki = 0.4 mM 0V5 C3 H7 O6 P C[C@H](C(=....
8 3UJR - PEP C3 H5 O6 P C=C(C(=O)O....
9 6D3Q Ki = 3.4 nM 4NG C4 H8 N O6 P C1[C@@H](C....
10 5ENL - 2PG C3 H7 O7 P C([C@H](C(....
11 2AL1 - PEP C3 H5 O6 P C=C(C(=O)O....
12 1ONE - PEP C3 H5 O6 P C=C(C(=O)O....
13 2XH2 - 2PG C3 H7 O7 P C([C@H](C(....
14 2XH4 - 2PG C3 H7 O7 P C([C@H](C(....
15 1L8P - PAH C2 H6 N O5 P C(C(=O)NO)....
16 1ELS Ki = 15 pM PAH C2 H6 N O5 P C(C(=O)NO)....
17 6ENL - PGA C2 H5 O6 P C(C(=O)O)O....
18 1EBG Ki = 15 pM PAH C2 H6 N O5 P C(C(=O)NO)....
19 1P48 - PEP C3 H5 O6 P C=C(C(=O)O....
20 2ONE - PEP C3 H5 O6 P C=C(C(=O)O....
21 2XH7 - 2PG C3 H7 O7 P C([C@H](C(....
22 2XH0 - PEP C3 H5 O6 P C=C(C(=O)O....
23 2XGZ - PEP C3 H5 O6 P C=C(C(=O)O....
24 7ENL - 2PG C3 H7 O7 P C([C@H](C(....
25 1P43 - 2PG C3 H7 O7 P C([C@H](C(....
26 4A3R Ki = 5 mM CIT C6 H8 O7 C(C(=O)O)C....
27 5BOE - PEP C3 H5 O6 P C=C(C(=O)O....
28 3QTP - 2PG C3 H7 O7 P C([C@H](C(....
29 2PTZ - PAH C2 H6 N O5 P C(C(=O)NO)....
30 2PU1 - FSG C2 H5 F N O5 P [C@H](C(=O....
31 2PTY - PEP C3 H5 O6 P C=C(C(=O)O....
32 2PU0 - PAH C2 H6 N O5 P C(C(=O)NO)....
33 1PDZ Ki = 0.2 mM PGA C2 H5 O6 P C(C(=O)O)O....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 0V5; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 PEQ 1 1
2 0V5 1 1
3 TPO 0.5 0.727273
4 PEZ 0.5 0.833333
5 2PG 0.482759 0.705882
6 XSP 0.466667 0.923077
7 3PG 0.40625 0.727273
8 DG2 0.4 0.75
Ligand no: 2; Ligand: XSP; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 XSP 1 1
2 PEQ 0.466667 0.923077
3 0V5 0.466667 0.923077
4 2PG 0.451613 0.757576
5 PEZ 0.424242 0.774194
Similar Ligands (3D)
Ligand no: 1; Ligand: 0V5; Similar ligands found: 574
No: Ligand Similarity coefficient
1 PEP 1.0000
2 GZ3 0.9881
3 SPV 0.9840
4 R67 0.9817
5 3SL 0.9737
6 PPR 0.9661
7 PGA 0.9629
8 FB2 0.9572
9 LEU 0.9517
10 ASP 0.9513
11 AKG 0.9513
12 PMB 0.9494
13 LMR 0.9491
14 OAA 0.9472
15 ASN 0.9470
16 ACH 0.9458
17 COI 0.9456
18 PAH 0.9454
19 LLQ 0.9450
20 DS0 0.9437
21 HG3 0.9436
22 IOM 0.9427
23 DYA 0.9418
24 JYD 0.9411
25 CMS 0.9406
26 2RH 0.9396
27 KVP 0.9392
28 X1S 0.9385
29 CIZ 0.9384
30 TEO 0.9381
31 G2H 0.9380
32 40E 0.9373
33 AL0 0.9372
34 1SA 0.9372
35 GP9 0.9354
36 152 0.9348
37 HL5 0.9342
38 TSU 0.9336
39 A09 0.9333
40 GLN 0.9328
41 MLT 0.9325
42 ITN 0.9322
43 GLU 0.9319
44 8K2 0.9315
45 2PN 0.9294
46 SAN 0.9294
47 3PP 0.9294
48 1GP 0.9290
49 DGL 0.9290
50 DGN 0.9289
51 4J8 0.9283
52 1SH 0.9283
53 AAS 0.9279
54 FBS 0.9275
55 G3P 0.9268
56 PGH 0.9266
57 G3H 0.9263
58 13P 0.9260
59 LTL 0.9260
60 HBU 0.9252
61 CRN 0.9251
62 FCR 0.9247
63 173 0.9239
64 1DV 0.9233
65 1DQ 0.9227
66 BAM 0.9219
67 GVM 0.9217
68 GUA 0.9217
69 98J 0.9212
70 BEN 0.9211
71 PBC 0.9211
72 POP 0.9211
73 CYX 0.9209
74 BEZ 0.9203
75 PPV 0.9200
76 FCN 0.9199
77 CCD 0.9193
78 NCA 0.9189
79 CFI 0.9188
80 6M4 0.9188
81 PSE 0.9187
82 HX2 0.9187
83 DAS 0.9186
84 SRT 0.9184
85 PZA 0.9182
86 QMP 0.9180
87 IP8 0.9180
88 SIN 0.9175
89 TLA 0.9175
90 2CO 0.9174
91 UNU 0.9172
92 MDN 0.9170
93 HIO 0.9170
94 SEP 0.9169
95 NIO 0.9168
96 PHB 0.9165
97 A20 0.9164
98 FB1 0.9163
99 6PC 0.9163
100 6JN 0.9160
101 FUM 0.9159
102 2AS 0.9158
103 TAR 0.9157
104 FBV 0.9154
105 ICF 0.9153
106 NBZ 0.9151
107 MAE 0.9147
108 X0V 0.9143
109 ILE 0.9137
110 3LR 0.9137
111 KMH 0.9136
112 AHB 0.9134
113 PLU 0.9133
114 NPO 0.9130
115 3HB 0.9129
116 DAL DAL 0.9128
117 GAB 0.9127
118 PC 0.9127
119 NTN 0.9126
120 ISZ 0.9124
121 2IT 0.9119
122 GGL 0.9119
123 BE2 0.9118
124 2HG 0.9115
125 51R 0.9112
126 HZP 0.9111
127 ONL 0.9110
128 P22 0.9109
129 SD4 0.9105
130 4LR 0.9105
131 OPE 0.9102
132 NM2 0.9101
133 NM3 0.9101
134 PIS 0.9101
135 AMS 0.9100
136 3NT 0.9099
137 RHU 0.9097
138 IFP 0.9096
139 SAL 0.9095
140 SKG 0.9091
141 URP 0.9090
142 BHO 0.9090
143 SYM 0.9088
144 PAB 0.9085
145 LNO 0.9081
146 MLE 0.9079
147 VGL 0.9079
148 ES6 0.9078
149 KVV 0.9077
150 93K 0.9075
151 TB6 0.9073
152 ZGL 0.9072
153 SS2 0.9072
154 INO 0.9071
155 ORN 0.9071
156 YCP 0.9070
157 AT3 0.9070
158 OSE 0.9069
159 PBZ 0.9063
160 DHB 0.9062
161 S0H 0.9060
162 NMG 0.9058
163 9ON 0.9057
164 S2G 0.9057
165 FBW 0.9056
166 SPA 0.9055
167 7N0 0.9054
168 DBX 0.9053
169 Z82 0.9053
170 GPJ 0.9050
171 GPF 0.9050
172 IHG 0.9048
173 AC6 0.9047
174 MYJ 0.9046
175 H95 0.9042
176 XCZ 0.9039
177 4MV 0.9038
178 VAL 0.9038
179 URQ 0.9036
180 HPS 0.9035
181 UGC 0.9032
182 PMF 0.9032
183 8EW 0.9029
184 QY9 0.9029
185 MET 0.9028
186 GJZ 0.9027
187 JKE 0.9026
188 TZC 0.9024
189 DQY 0.9019
190 1Y6 0.9019
191 RMN 0.9018
192 NLE 0.9017
193 NIZ 0.9017
194 XLS 0.9015
195 DAB 0.9015
196 RNT 0.9014
197 OVV 0.9014
198 4NC 0.9013
199 60P 0.9011
200 23J 0.9010
201 NXA 0.9010
202 SMN 0.9006
203 QSC 0.9005
204 SS1 0.9004
205 ODV 0.9004
206 PZI 0.9003
207 BNS 0.9001
208 9RW 0.9001
209 4MA 0.9000
210 3YP 0.8999
211 HSE 0.8999
212 XYL 0.8995
213 RB5 0.8995
214 TIU 0.8995
215 HIS 0.8989
216 HBD 0.8989
217 RBL 0.8987
218 4SX 0.8986
219 ROR 0.8986
220 3U4 0.8985
221 FEH 0.8984
222 SC2 0.8983
223 GAG 0.8983
224 HYP 0.8982
225 7VD 0.8982
226 SMV 0.8981
227 P72 0.8975
228 7BC 0.8975
229 GG6 0.8974
230 NVA 0.8974
231 IZC 0.8973
232 3OC 0.8969
233 9YL 0.8969
234 SYC 0.8969
235 FQI 0.8968
236 JBN 0.8967
237 53C 0.8967
238 4CS 0.8967
239 7WG 0.8967
240 IXW 0.8967
241 HMS 0.8964
242 OEM 0.8964
243 2PC 0.8963
244 VNJ 0.8962
245 9X6 0.8961
246 EKZ 0.8961
247 DCO 0.8961
248 HDA 0.8961
249 129 0.8960
250 8OZ 0.8957
251 CCE 0.8952
252 2HO 0.8951
253 PAE 0.8949
254 K5W 0.8948
255 SHF 0.8948
256 E4P 0.8947
257 MED 0.8946
258 KIV 0.8943
259 I4B 0.8941
260 MTL 0.8940
261 PAC 0.8940
262 9X7 0.8939
263 4FH 0.8937
264 GLY ALA 0.8937
265 K34 0.8935
266 1P3 0.8932
267 GRO 0.8929
268 F9P 0.8928
269 PYC 0.8927
270 TFB 0.8926
271 OGA 0.8925
272 8GL 0.8925
273 MUC 0.8924
274 EDR 0.8923
275 B85 0.8923
276 FAN 0.8923
277 TP5 0.8922
278 MNN 0.8921
279 HSM 0.8921
280 FBT 0.8918
281 CP 0.8917
282 PRO 0.8913
283 UY7 0.8912
284 LYS 0.8909
285 7A8 0.8908
286 QDK 0.8907
287 RSO 0.8907
288 SHA 0.8906
289 SOL 0.8906
290 DYT 0.8906
291 M58 0.8906
292 OK7 0.8904
293 DOB 0.8903
294 RNS 0.8901
295 MPD 0.8901
296 HPV 0.8901
297 FSG 0.8900
298 URS 0.8898
299 TPA 0.8897
300 PG3 0.8895
301 DCL 0.8894
302 PHU 0.8893
303 UYA 0.8891
304 RAT 0.8888
305 3BZ 0.8888
306 273 0.8887
307 I1E 0.8884
308 LY0 0.8884
309 1DJ 0.8883
310 SW7 0.8883
311 CXF 0.8881
312 SOR 0.8878
313 TIH 0.8876
314 GLY GLY 0.8876
315 IT2 0.8875
316 14J 0.8874
317 PCT 0.8873
318 GLO 0.8869
319 ZBT 0.8868
320 TZL 0.8868
321 XUL 0.8867
322 3V4 0.8865
323 2D8 0.8865
324 5CU 0.8864
325 THR 0.8864
326 3AB 0.8862
327 FOA 0.8862
328 CDV 0.8860
329 OTR 0.8859
330 MXN 0.8859
331 5AC 0.8859
332 FA0 0.8859
333 3BU 0.8858
334 69O 0.8857
335 EHM 0.8856
336 C5A 0.8854
337 HYA 0.8854
338 HBA 0.8854
339 GYE 0.8852
340 K7M 0.8851
341 BAE 0.8850
342 SVD 0.8850
343 IP0 0.8848
344 SJ5 0.8841
345 3SK 0.8841
346 AC0 0.8840
347 J9T 0.8840
348 THE 0.8839
349 FBM 0.8839
350 MRZ 0.8835
351 ASC 0.8834
352 4P5 0.8833
353 RTK 0.8833
354 XBT 0.8832
355 SAT 0.8827
356 BZ3 0.8827
357 0OC 0.8826
358 54D 0.8825
359 C21 0.8825
360 FLA 0.8824
361 R9S 0.8823
362 HCI 0.8821
363 DHS 0.8818
364 3FH 0.8816
365 T2C 0.8815
366 FK8 0.8815
367 RIP 0.8815
368 AC5 0.8813
369 JZ7 0.8813
370 HCS 0.8813
371 HSO 0.8812
372 DMV 0.8809
373 XXG 0.8807
374 PCA 0.8805
375 FA1 0.8805
376 069 0.8805
377 JZ5 0.8804
378 XRG 0.8803
379 BZX 0.8802
380 9TZ 0.8801
381 TZE 0.8800
382 4HP 0.8799
383 GBD 0.8798
384 FUC 0.8798
385 VAH 0.8797
386 4VP 0.8797
387 HDH 0.8796
388 1WD 0.8796
389 KMT 0.8794
390 9YT 0.8794
391 XM0 0.8792
392 OHP 0.8792
393 3S5 0.8790
394 4SV 0.8790
395 FP1 0.8788
396 LPK 0.8786
397 XX2 0.8782
398 4M0 0.8782
399 MRY 0.8781
400 RUJ 0.8781
401 8EZ 0.8780
402 MZT 0.8777
403 APG 0.8775
404 I38 0.8775
405 OXQ 0.8775
406 PEL 0.8775
407 N8P 0.8773
408 MEQ 0.8772
409 IQ0 0.8771
410 2LP 0.8768
411 1DU 0.8767
412 LNR 0.8767
413 GLY CYS 0.8767
414 2AL 0.8767
415 PRS 0.8767
416 NK2 0.8766
417 271 0.8764
418 GCO 0.8764
419 GBN 0.8764
420 1LN 0.8764
421 LEA 0.8763
422 3HA 0.8763
423 AHN 0.8763
424 M6W 0.8761
425 HTX 0.8760
426 HY1 0.8760
427 6NA 0.8758
428 41K 0.8758
429 M3H 0.8758
430 23W 0.8757
431 KOJ 0.8756
432 PEA 0.8755
433 5XB 0.8754
434 MNM 0.8753
435 DBH 0.8753
436 GTK 0.8751
437 K6H 0.8747
438 8GC 0.8747
439 WCE 0.8747
440 EDG 0.8746
441 3HP 0.8744
442 ORO 0.8744
443 DOR 0.8740
444 URF 0.8739
445 261 0.8738
446 T9G 0.8735
447 KBB 0.8733
448 ABU 0.8732
449 HBX 0.8730
450 3M0 0.8728
451 A13 0.8720
452 JLZ 0.8719
453 HF2 0.8718
454 NMJ 0.8717
455 7WV 0.8716
456 LER 0.8710
457 PPY 0.8710
458 PAF 0.8708
459 FBJ 0.8703
460 51F 0.8702
461 2CK 0.8700
462 HY3 0.8699
463 5OB 0.8698
464 PYD 0.8693
465 826 0.8693
466 CXP 0.8691
467 EYK 0.8690
468 PKU 0.8687
469 DE5 0.8687
470 34D 0.8687
471 PHE 0.8684
472 NNO 0.8684
473 KPL 0.8684
474 M4T 0.8683
475 SNE 0.8681
476 HFA 0.8681
477 BE7 0.8681
478 M4S 0.8679
479 N4B 0.8678
480 1X4 0.8676
481 MSE 0.8675
482 O7U 0.8675
483 4ZA 0.8674
484 MJ2 0.8674
485 2FY 0.8674
486 SIF 0.8674
487 4PN 0.8674
488 NCT 0.8672
489 TH7 0.8670
490 4FA 0.8668
491 RM1 0.8668
492 CSS 0.8665
493 4JC 0.8664
494 LDP 0.8663
495 AMC 0.8662
496 4A3 0.8661
497 WBU 0.8660
498 NK 0.8660
499 AEF 0.8659
500 DHK 0.8658
501 HMU 0.8655
502 RBJ 0.8655
503 FHB 0.8654
504 449 0.8654
505 ABN 0.8651
506 SKM 0.8650
507 IDM 0.8648
508 BDF 0.8647
509 SYN 0.8645
510 BMA 0.8644
511 FUL 0.8644
512 G4D 0.8642
513 9TY 0.8640
514 3F0 0.8639
515 FYU 0.8637
516 KTA 0.8636
517 4NG 0.8635
518 6CS 0.8635
519 M45 0.8634
520 BP9 0.8633
521 MAK 0.8632
522 HPA 0.8630
523 174 0.8626
524 PSJ 0.8624
525 HMH 0.8622
526 HHA 0.8622
527 CS2 0.8621
528 D1X 0.8621
529 FPY 0.8621
530 GZL 0.8621
531 23B 0.8619
532 PIM 0.8619
533 IFL 0.8617
534 LRH 0.8615
535 ABE 0.8615
536 4XR 0.8614
537 PBE 0.8613
538 7HP 0.8611
539 5HN 0.8610
540 GLL 0.8609
541 TYE 0.8608
542 24B 0.8605
543 DMJ 0.8605
544 8H8 0.8603
545 4SD 0.8602
546 FRU 0.8600
547 WOT 0.8600
548 282 0.8598
549 NOJ 0.8597
550 45L 0.8596
551 RJY 0.8595
552 JFJ 0.8595
553 LDU 0.8592
554 Q88 0.8592
555 4WL 0.8590
556 ALO 0.8590
557 ADE 0.8590
558 XAN 0.8586
559 6OT 0.8584
560 R2B 0.8584
561 5NI 0.8583
562 Q02 0.8582
563 IFM 0.8578
564 FPI 0.8574
565 4JL 0.8571
566 SSN 0.8568
567 GUN 0.8565
568 265 0.8562
569 2KT 0.8562
570 PBA 0.8561
571 1SP 0.8556
572 3AL 0.8540
573 GIF 0.8540
574 6M9 0.8530
Ligand no: 2; Ligand: XSP; Similar ligands found: 412
No: Ligand Similarity coefficient
1 PEP 0.9684
2 FB2 0.9429
3 G2H 0.9417
4 SPV 0.9410
5 DCO 0.9402
6 PMB 0.9394
7 R67 0.9392
8 GZ3 0.9389
9 MLE 0.9384
10 3SL 0.9342
11 3PG 0.9338
12 A13 0.9321
13 MJ2 0.9297
14 NFQ 0.9286
15 23J 0.9281
16 PPR 0.9276
17 CDV 0.9260
18 EKZ 0.9256
19 XCZ 0.9246
20 5RG 0.9241
21 GLU 0.9229
22 K5W 0.9229
23 LEU 0.9228
24 GLN 0.9224
25 JYD 0.9220
26 LMR 0.9219
27 FBW 0.9211
28 ASP 0.9206
29 GTQ 0.9203
30 51R 0.9201
31 ASN 0.9200
32 PZI 0.9184
33 CIZ 0.9183
34 HL5 0.9183
35 FBU 0.9173
36 5M0 0.9166
37 UFV 0.9160
38 ORO 0.9153
39 BE2 0.9152
40 FBV 0.9150
41 D1X 0.9147
42 GAB 0.9147
43 DOR 0.9132
44 DHK 0.9131
45 CFI 0.9131
46 54G 0.9125
47 4FH 0.9125
48 BEN 0.9124
49 FB1 0.9123
50 CMS 0.9120
51 2AL 0.9119
52 X0V 0.9118
53 34D 0.9117
54 RHU 0.9111
55 AL0 0.9110
56 BEZ 0.9108
57 A09 0.9102
58 MYJ 0.9098
59 FCR 0.9097
60 3NT 0.9097
61 3HB 0.9094
62 SAL 0.9093
63 OXC 0.9090
64 PRZ 0.9082
65 IFP 0.9077
66 DHB 0.9076
67 SHA 0.9076
68 COI 0.9075
69 BAM 0.9075
70 OAA 0.9072
71 SVD 0.9064
72 HIO 0.9063
73 OVV 0.9060
74 DS0 0.9059
75 SIF 0.9057
76 53C 0.9056
77 4NC 0.9054
78 IOM 0.9051
79 6PC 0.9050
80 13P 0.9046
81 NIO 0.9046
82 4CS 0.9037
83 MLT 0.9037
84 9TZ 0.9035
85 QMP 0.9034
86 TRA 0.9032
87 P9P 0.9030
88 SEP 0.9029
89 VNL 0.9027
90 6M4 0.9024
91 1SA 0.9022
92 8OZ 0.9022
93 9TW 0.9020
94 P4B 0.9019
95 3FH 0.9018
96 SC2 0.9009
97 40E 0.9005
98 AN0 0.9003
99 HBU 0.8999
100 ORN 0.8998
101 PHU 0.8998
102 GAG 0.8994
103 GP9 0.8990
104 GJZ 0.8985
105 LLQ 0.8979
106 OSE 0.8979
107 ES6 0.8978
108 ICT 0.8975
109 QY9 0.8973
110 3OC 0.8970
111 AW5 0.8966
112 7N0 0.8963
113 R9S 0.8963
114 1AL 0.8963
115 MWP 0.8961
116 BNS 0.8960
117 SRT 0.8958
118 CIT 0.8957
119 6OT 0.8955
120 CRN 0.8951
121 FOC 0.8950
122 ITN 0.8950
123 TPO 0.8948
124 AKG 0.8943
125 TLA 0.8942
126 EDR 0.8942
127 98J 0.8941
128 1DV 0.8936
129 5MK 0.8936
130 SS2 0.8936
131 KTA 0.8935
132 IPM 0.8935
133 DBX 0.8934
134 4NG 0.8933
135 NMJ 0.8933
136 1LQ 0.8932
137 4SX 0.8930
138 3BU 0.8926
139 2AS 0.8926
140 X09 0.8926
141 3HA 0.8923
142 DBH 0.8923
143 IP0 0.8922
144 HPV 0.8921
145 ICF 0.8917
146 F9P 0.8914
147 CXF 0.8914
148 Q6T 0.8912
149 RMN 0.8910
150 URS 0.8908
151 PAC 0.8906
152 TEO 0.8903
153 TAR 0.8901
154 ONL 0.8898
155 Q88 0.8898
156 SKG 0.8895
157 SYM 0.8895
158 G3H 0.8894
159 URQ 0.8894
160 FP1 0.8894
161 TRC 0.8893
162 6JN 0.8893
163 PLU 0.8892
164 J9T 0.8890
165 3BZ 0.8890
166 SD4 0.8890
167 KBB 0.8887
168 9J3 0.8886
169 9DG 0.8886
170 3Z8 0.8885
171 6CS 0.8885
172 3SK 0.8883
173 GLY CYS 0.8877
174 VPR 0.8877
175 SKM 0.8877
176 QSC 0.8875
177 3IT 0.8875
178 XX2 0.8870
179 G3P 0.8869
180 MET 0.8868
181 7A3 0.8867
182 RSO 0.8866
183 293 0.8866
184 FLC 0.8865
185 2D8 0.8864
186 LY0 0.8862
187 ENL 0.8861
188 92K 0.8860
189 3AB 0.8860
190 9ON 0.8857
191 OEM 0.8853
192 261 0.8851
193 P22 0.8849
194 FPK 0.8849
195 IJZ 0.8847
196 PGA 0.8847
197 8EW 0.8846
198 1WD 0.8846
199 HPS 0.8844
200 4SV 0.8843
201 OGA 0.8842
202 3F0 0.8841
203 2CO 0.8840
204 DHS 0.8840
205 3MV 0.8839
206 GYE 0.8837
207 1P3 0.8835
208 SS1 0.8834
209 HPA 0.8834
210 XM0 0.8832
211 8GC 0.8831
212 SJ5 0.8830
213 ACH 0.8827
214 AKH 0.8826
215 CTS 0.8825
216 ASC 0.8824
217 IPZ 0.8824
218 NCD 0.8823
219 3M0 0.8819
220 HIS 0.8819
221 791 0.8818
222 2IT 0.8815
223 3AL 0.8814
224 WCE 0.8811
225 2TQ 0.8810
226 N8P 0.8808
227 YCP 0.8807
228 2RH 0.8807
229 FA3 0.8806
230 BGC 0.8806
231 DGL 0.8804
232 TPA 0.8804
233 KOJ 0.8802
234 M58 0.8801
235 SWA 0.8797
236 CCB 0.8796
237 DCL 0.8796
238 AS3 0.8796
239 GLC 0.8795
240 1GP 0.8793
241 PMF 0.8791
242 DQA 0.8791
243 EYK 0.8790
244 JFJ 0.8785
245 GUN 0.8784
246 GBN 0.8784
247 GTR 0.8781
248 7HP 0.8781
249 FOT 0.8776
250 AHB 0.8775
251 GCB 0.8775
252 G8M 0.8767
253 FEH 0.8764
254 TZE 0.8763
255 DAS 0.8762
256 FA1 0.8759
257 5AC 0.8759
258 3MB 0.8758
259 DYT 0.8755
260 PAH 0.8752
261 HSE 0.8751
262 4XR 0.8751
263 GRO 0.8749
264 4WK 0.8745
265 BDP 0.8744
266 CDT 0.8741
267 7MU 0.8740
268 QUS 0.8739
269 069 0.8737
270 GBD 0.8735
271 51F 0.8735
272 ADE 0.8735
273 0OC 0.8734
274 XYL 0.8732
275 RB5 0.8732
276 OVM 0.8732
277 N7P 0.8730
278 ZXD 0.8728
279 NVA 0.8728
280 OHP 0.8728
281 DAL DAL 0.8727
282 DYA 0.8725
283 M4T 0.8723
284 GAL 0.8721
285 QIC 0.8721
286 2LP 0.8720
287 8GL 0.8719
288 DAB 0.8718
289 ZZ3 0.8718
290 ALA PRO 0.8715
291 DII 0.8713
292 XXG 0.8712
293 ASO 0.8712
294 FGZ 0.8711
295 KDF 0.8709
296 3CU 0.8704
297 VOH 0.8703
298 I4B 0.8702
299 G4D 0.8701
300 TAG 0.8700
301 YIO 0.8700
302 FRU 0.8700
303 210 0.8699
304 V55 0.8698
305 RNS 0.8698
306 LNR 0.8693
307 OMD 0.8693
308 GLA 0.8691
309 PEA 0.8690
310 ZGL 0.8690
311 GCU 0.8689
312 AIN 0.8688
313 EV0 0.8687
314 XUL 0.8684
315 NTC 0.8682
316 9RW 0.8682
317 IHG 0.8680
318 F31 0.8677
319 NXA 0.8676
320 7HQ 0.8674
321 149 0.8673
322 ILE 0.8673
323 1LN 0.8672
324 S76 0.8672
325 5HN 0.8671
326 TZL 0.8671
327 ZBT 0.8671
328 ADA 0.8671
329 RAT 0.8670
330 GCO 0.8668
331 ATH 0.8667
332 QDK 0.8665
333 2MN 0.8664
334 PEL 0.8664
335 E7Z 0.8663
336 PBE 0.8661
337 SYC 0.8661
338 EKN 0.8660
339 M0Q 0.8659
340 PGH 0.8657
341 GLY PRO 0.8656
342 URP 0.8656
343 LDP 0.8655
344 HLZ 0.8653
345 LFR 0.8652
346 R8V 0.8652
347 7A2 0.8651
348 HCS 0.8646
349 M1E 0.8644
350 2D0 0.8644
351 SOR 0.8642
352 9X7 0.8641
353 6XI 0.8641
354 SF9 0.8640
355 RIB 0.8640
356 BRT 0.8640
357 MNM 0.8635
358 IFL 0.8632
359 LGC 0.8631
360 ROR 0.8630
361 FE DB1 0.8627
362 2FG 0.8627
363 0W8 0.8625
364 2A7 0.8624
365 CXP 0.8620
366 C2U 0.8617
367 24W 0.8616
368 12M 0.8615
369 SOE 0.8614
370 MED 0.8610
371 CWM 0.8609
372 NCT 0.8608
373 F0J 0.8606
374 N5J 0.8606
375 HYP 0.8605
376 GV9 0.8604
377 XX3 0.8601
378 KLW 0.8601
379 NOJ 0.8600
380 GAF 0.8599
381 DA4 0.8598
382 HY3 0.8595
383 LPK 0.8595
384 7ME 0.8586
385 LT2 0.8578
386 GIF 0.8573
387 42J 0.8571
388 3S4 0.8569
389 B85 0.8567
390 SX1 0.8566
391 DBJ 0.8565
392 1LM 0.8564
393 9KH 0.8562
394 1SQ 0.8562
395 HMU 0.8559
396 HDA 0.8558
397 HQY 0.8558
398 KT7 0.8554
399 GTK 0.8553
400 RM1 0.8552
401 HA7 0.8550
402 GLO 0.8548
403 O72 0.8547
404 EHM 0.8547
405 9PY 0.8543
406 MRZ 0.8542
407 JZ7 0.8535
408 AZA 0.8532
409 OVP 0.8529
410 SWD 0.8521
411 M1H 0.8520
412 X6X 0.8516
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4ZCW; Ligand: 4NG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4zcw.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4ZCW; Ligand: 4NG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4zcw.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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