Receptor
PDB id Resolution Class Description Source Keywords
3mfw 1.47 Å EC: 3.5.3.1 CRYSTAL STRUCTURE OF HUMAN ARGINASE I IN COMPLEX WITH L-2- AMINOHISTIDINE AND SULPHATE HOMO SAPIENS MANGANESE COORDINATION 2-AMINOIMIDAZOLE DERIVATIVE STRUCTUDESIGN HYDROLASE
Ref.: 2-AMINOIMIDAZOLE AMINO ACIDS AS INHIBITORS OF THE B MANGANESE METALLOENZYME HUMAN ARGINASE I. J.MED.CHEM. V. 53 4266 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
B3U A:600;
B:601;
 Valid;
Valid;
 none;
none;
 Ki = 300 uM
170.169 C6 H10 N4 O2 c1c([...
MN A:5362;
A:5363;
B:6362;
B:6363;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
 submit data
54.938 Mn [Mn+2...
SO4 A:551;
B:552;
 Invalid;
Invalid;
 none;
none;
 submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6V7E 1.99 Å EC: 3.5.3.1 HUMAN ARGINASE1 COMPLEXED WITH BICYCLIC INHIBITOR COMPOUND 1 HOMO SAPIENS AGONIST ARG (ARGINASE) BICYCLIC IMMUNOTHERAPY METALLOENZHYDROLASE HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Ref.: DISCOVERY AND OPTIMIZATION OF RATIONALLY DESIGNED B INHIBITORS OF HUMAN ARGINASE TO ENHANCE CANCER IMMUNOTHERAPY. ACS MED.CHEM.LETT. V. 11 582 2020
Members (30)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 3SKK - 4U7 C7 H15 B F2 N O5 [B-](CCCC[....
2 3GN0 Ki = 3.9 mM DMO C6 H12 F2 N2 O2 C(CC(C(F)F....
3 1WVA Kd = 270 nM S2C C5 H13 B N O5 S [B-](CCSC[....
4 3KV2 Kd = 47.51 nM NNH C5 H12 N4 O3 [H]/N=C(/N....
5 2PHO Kd > 0.1 mM TSZ C H5 N3 S C(=S)(N)NN
6 6V7D ic50 = 22 nM QR4 C11 H24 B N2 O5 [B-](CCC[C....
7 4IE1 - 1EC C9 H21 B N O6 [B-](CCCC[....
8 3MFW Ki = 300 uM B3U C6 H10 N4 O2 c1c([nH]c(....
9 3LP4 Kd = 13100 nM LYS C6 H15 N2 O2 C(CC[NH3+]....
10 3GMZ - ORN C5 H12 N2 O2 C(C[C@@H](....
11 4GSZ - ABH C6 H15 B N O5 [B-](CCCC[....
12 3SJT - 5AB C7 H17 B N O5 [B-](CCCC[....
13 2PLL Kd = 5 nM ABH C6 H15 B N O5 [B-](CCCC[....
14 3MFV Ki = 3000 uM Z70 C7 H12 N4 O2 c1c([nH]c(....
15 4GSV - ABH C6 H15 B N O5 [B-](CCCC[....
16 3DJ8 - EXY C8 H15 N O3 C1[C@H](O1....
17 1WVB - S2C C5 H13 B N O5 S [B-](CCSC[....
18 4HWW ic50 = 223 nM X7A C13 H28 B N2 O5 [B-](CCCC[....
19 3E6V Kd = 147 nM ABH C6 H15 B N O5 [B-](CCCC[....
20 3THH - ABH C6 H15 B N O5 [B-](CCCC[....
21 6V7E ic50 = 2 nM QRA C12 H24 B N2 O5 [B-](CCC[C....
22 3LP7 Kd = 3600 nM HAR C6 H14 N4 O3 C(C[C@@H](....
23 2AEB Kd = 5 nM ABH C6 H15 B N O5 [B-](CCCC[....
24 3THJ - ORN C5 H12 N2 O2 C(C[C@@H](....
25 6V7F ic50 = 14 nM QRJ C12 H26 B N2 O5 [B-](CCC[C....
26 3F80 Kd = 60 uM 6HN C6 H12 N2 O4 C(CC[N+](=....
27 3E6K Kd = 7000 nM ABH C6 H15 B N O5 [B-](CCCC[....
28 4HXQ ic50 = 60 nM X8A C14 H30 B N2 O5 [B-](CCCC[....
29 4GWD - ABH C6 H15 B N O5 [B-](CCCC[....
30 6V7C ic50 = 29 nM QR1 C11 H24 B N2 O5 [B-](CCC[C....
70% Homology Family (46)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 3SKK - 4U7 C7 H15 B F2 N O5 [B-](CCCC[....
2 3GN0 Ki = 3.9 mM DMO C6 H12 F2 N2 O2 C(CC(C(F)F....
3 1WVA Kd = 270 nM S2C C5 H13 B N O5 S [B-](CCSC[....
4 3KV2 Kd = 47.51 nM NNH C5 H12 N4 O3 [H]/N=C(/N....
5 2PHO Kd > 0.1 mM TSZ C H5 N3 S C(=S)(N)NN
6 6V7D ic50 = 22 nM QR4 C11 H24 B N2 O5 [B-](CCC[C....
7 4IE1 - 1EC C9 H21 B N O6 [B-](CCCC[....
8 3MFW Ki = 300 uM B3U C6 H10 N4 O2 c1c([nH]c(....
9 3LP4 Kd = 13100 nM LYS C6 H15 N2 O2 C(CC[NH3+]....
10 3GMZ - ORN C5 H12 N2 O2 C(C[C@@H](....
11 4GSZ - ABH C6 H15 B N O5 [B-](CCCC[....
12 3SJT - 5AB C7 H17 B N O5 [B-](CCCC[....
13 2PLL Kd = 5 nM ABH C6 H15 B N O5 [B-](CCCC[....
14 3MFV Ki = 3000 uM Z70 C7 H12 N4 O2 c1c([nH]c(....
15 4GSV - ABH C6 H15 B N O5 [B-](CCCC[....
16 3DJ8 - EXY C8 H15 N O3 C1[C@H](O1....
17 1WVB - S2C C5 H13 B N O5 S [B-](CCSC[....
18 4HWW ic50 = 223 nM X7A C13 H28 B N2 O5 [B-](CCCC[....
19 3E6V Kd = 147 nM ABH C6 H15 B N O5 [B-](CCCC[....
20 3THH - ABH C6 H15 B N O5 [B-](CCCC[....
21 6V7E ic50 = 2 nM QRA C12 H24 B N2 O5 [B-](CCC[C....
22 3LP7 Kd = 3600 nM HAR C6 H14 N4 O3 C(C[C@@H](....
23 2AEB Kd = 5 nM ABH C6 H15 B N O5 [B-](CCCC[....
24 3THJ - ORN C5 H12 N2 O2 C(C[C@@H](....
25 6V7F ic50 = 14 nM QRJ C12 H26 B N2 O5 [B-](CCC[C....
26 3F80 Kd = 60 uM 6HN C6 H12 N2 O4 C(CC[N+](=....
27 3E6K Kd = 7000 nM ABH C6 H15 B N O5 [B-](CCCC[....
28 4HXQ ic50 = 60 nM X8A C14 H30 B N2 O5 [B-](CCCC[....
29 4GWD - ABH C6 H15 B N O5 [B-](CCCC[....
30 6V7C ic50 = 29 nM QR1 C11 H24 B N2 O5 [B-](CCC[C....
31 4I06 ic50 = 67 nM X8A C14 H30 B N2 O5 [B-](CCCC[....
32 4IXV ic50 = 240 nM XA1 C18 H29 B Cl N2 O5 [B-](CCCC[....
33 4IE3 ic50 = 980 nM 1EE C13 H28 B N2 O6 [B-](CCCC[....
34 4IE2 ic50 = 4500 nM 1EC C9 H21 B N O6 [B-](CCCC[....
35 4HZE ic50 = 509 nM X7A C13 H28 B N2 O5 [B-](CCCC[....
36 6Q37 ic50 = 440 nM HE8 C8 H18 B N2 O5 [B-](CCC[C....
37 6Q39 ic50 = 16 nM HDQ C14 H29 B N3 O5 [B-](CCC[C....
38 4IXU ic50 = 23 nM 38I C20 H30 B Cl2 N2 O5 [B-](CCCC[....
39 1T5G - ARG C6 H15 N4 O2 C(C[C@@H](....
40 1D3V Kd = 0.11 uM ABH C6 H15 B N O5 [B-](CCCC[....
41 1HQG - ORN C5 H12 N2 O2 C(C[C@@H](....
42 1T4T ic50 < 400 uM DIR C4 H10 N4 O3 C([C@@H](C....
43 1T5F Ki = 60 uM DHH C7 H15 N O4 C(CCC(O)O)....
44 1P8R - S2C C5 H13 B N O5 S [B-](CCSC[....
45 1HQ5 Kd = 2.22 uM S2C C5 H13 B N O5 S [B-](CCSC[....
46 3E9B Ki = 4500 nM S2C C5 H13 B N O5 S [B-](CCSC[....
50% Homology Family (61)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4Q3S Kd = 0.26 uM X7A C13 H28 B N2 O5 [B-](CCCC[....
2 4Q42 - ORN C5 H12 N2 O2 C(C[C@@H](....
3 4Q40 - VAL C5 H11 N O2 CC(C)[C@@H....
4 4Q3U Kd = 0.36 uM NNH C5 H12 N4 O3 [H]/N=C(/N....
5 4Q41 - LYS C6 H15 N2 O2 C(CC[NH3+]....
6 4Q3Q Kd = 1.3 uM ABH C6 H15 B N O5 [B-](CCCC[....
7 4Q3T Kd = 0.33 uM HAR C6 H14 N4 O3 C(C[C@@H](....
8 3SKK - 4U7 C7 H15 B F2 N O5 [B-](CCCC[....
9 3GN0 Ki = 3.9 mM DMO C6 H12 F2 N2 O2 C(CC(C(F)F....
10 1WVA Kd = 270 nM S2C C5 H13 B N O5 S [B-](CCSC[....
11 3KV2 Kd = 47.51 nM NNH C5 H12 N4 O3 [H]/N=C(/N....
12 2PHO Kd > 0.1 mM TSZ C H5 N3 S C(=S)(N)NN
13 6V7D ic50 = 22 nM QR4 C11 H24 B N2 O5 [B-](CCC[C....
14 4IE1 - 1EC C9 H21 B N O6 [B-](CCCC[....
15 3MFW Ki = 300 uM B3U C6 H10 N4 O2 c1c([nH]c(....
16 3LP4 Kd = 13100 nM LYS C6 H15 N2 O2 C(CC[NH3+]....
17 3GMZ - ORN C5 H12 N2 O2 C(C[C@@H](....
18 4GSZ - ABH C6 H15 B N O5 [B-](CCCC[....
19 3SJT - 5AB C7 H17 B N O5 [B-](CCCC[....
20 2PLL Kd = 5 nM ABH C6 H15 B N O5 [B-](CCCC[....
21 3MFV Ki = 3000 uM Z70 C7 H12 N4 O2 c1c([nH]c(....
22 4GSV - ABH C6 H15 B N O5 [B-](CCCC[....
23 3DJ8 - EXY C8 H15 N O3 C1[C@H](O1....
24 1WVB - S2C C5 H13 B N O5 S [B-](CCSC[....
25 4HWW ic50 = 223 nM X7A C13 H28 B N2 O5 [B-](CCCC[....
26 3E6V Kd = 147 nM ABH C6 H15 B N O5 [B-](CCCC[....
27 3THH - ABH C6 H15 B N O5 [B-](CCCC[....
28 6V7E ic50 = 2 nM QRA C12 H24 B N2 O5 [B-](CCC[C....
29 3LP7 Kd = 3600 nM HAR C6 H14 N4 O3 C(C[C@@H](....
30 2AEB Kd = 5 nM ABH C6 H15 B N O5 [B-](CCCC[....
31 3THJ - ORN C5 H12 N2 O2 C(C[C@@H](....
32 6V7F ic50 = 14 nM QRJ C12 H26 B N2 O5 [B-](CCC[C....
33 3F80 Kd = 60 uM 6HN C6 H12 N2 O4 C(CC[N+](=....
34 3E6K Kd = 7000 nM ABH C6 H15 B N O5 [B-](CCCC[....
35 4HXQ ic50 = 60 nM X8A C14 H30 B N2 O5 [B-](CCCC[....
36 4GWD - ABH C6 H15 B N O5 [B-](CCCC[....
37 6V7C ic50 = 29 nM QR1 C11 H24 B N2 O5 [B-](CCC[C....
38 4I06 ic50 = 67 nM X8A C14 H30 B N2 O5 [B-](CCCC[....
39 4IXV ic50 = 240 nM XA1 C18 H29 B Cl N2 O5 [B-](CCCC[....
40 4IE3 ic50 = 980 nM 1EE C13 H28 B N2 O6 [B-](CCCC[....
41 4IE2 ic50 = 4500 nM 1EC C9 H21 B N O6 [B-](CCCC[....
42 4HZE ic50 = 509 nM X7A C13 H28 B N2 O5 [B-](CCCC[....
43 6Q37 ic50 = 440 nM HE8 C8 H18 B N2 O5 [B-](CCC[C....
44 6Q39 ic50 = 16 nM HDQ C14 H29 B N3 O5 [B-](CCC[C....
45 4IXU ic50 = 23 nM 38I C20 H30 B Cl2 N2 O5 [B-](CCCC[....
46 4IU4 Ki ~ 10 uM S2C C5 H13 B N O5 S [B-](CCSC[....
47 4IU1 Ki ~ 50 uM NNH C5 H12 N4 O3 [H]/N=C(/N....
48 4IU5 - ORN C5 H12 N2 O2 C(C[C@@H](....
49 4IU0 Ki = 1.3 uM ABH C6 H15 B N O5 [B-](CCCC[....
50 1T5G - ARG C6 H15 N4 O2 C(C[C@@H](....
51 1D3V Kd = 0.11 uM ABH C6 H15 B N O5 [B-](CCCC[....
52 1HQG - ORN C5 H12 N2 O2 C(C[C@@H](....
53 1T4T ic50 < 400 uM DIR C4 H10 N4 O3 C([C@@H](C....
54 1T5F Ki = 60 uM DHH C7 H15 N O4 C(CCC(O)O)....
55 1P8R - S2C C5 H13 B N O5 S [B-](CCSC[....
56 1HQ5 Kd = 2.22 uM S2C C5 H13 B N O5 S [B-](CCSC[....
57 3E9B Ki = 4500 nM S2C C5 H13 B N O5 S [B-](CCSC[....
58 5ZEE - HAR C6 H14 N4 O3 C(C[C@@H](....
59 5ZEF - NVA C5 H11 N O2 CCC[C@@H](....
60 5CEV - LYS C6 H15 N2 O2 C(CC[NH3+]....
61 3CEV - ARG C6 H15 N4 O2 C(C[C@@H](....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: B3U; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 B3U 1 1
2 Z70 0.6 0.926829
Similar Ligands (3D)
Ligand no: 1; Ligand: B3U; Similar ligands found: 470
No: Ligand Similarity coefficient
1 HIC 0.9888
2 HIS 0.9830
3 PHE 0.9771
4 NFA 0.9766
5 HJH 0.9709
6 PPY 0.9704
7 HFA 0.9670
8 SHI 0.9594
9 DYT 0.9594
10 AOT 0.9571
11 S2P 0.9560
12 HHH 0.9548
13 QUS 0.9525
14 P58 0.9516
15 HHI 0.9512
16 TIH 0.9499
17 0A9 0.9483
18 DPN 0.9480
19 56D 0.9472
20 ISA 0.9469
21 SMN 0.9459
22 4BF 0.9442
23 TYR 0.9431
24 GLN 0.9431
25 HF2 0.9419
26 KTJ 0.9415
27 2UB 0.9414
28 UN1 0.9411
29 R9M 0.9400
30 ENO 0.9388
31 HCI 0.9388
32 URO 0.9378
33 B40 0.9377
34 HNL 0.9368
35 XIZ 0.9367
36 BRH 0.9348
37 DHI 0.9347
38 1Z6 0.9345
39 R2P 0.9338
40 0OC 0.9325
41 NCT 0.9324
42 OTR 0.9315
43 PPT 0.9314
44 HPP 0.9313
45 DTY 0.9312
46 AHC 0.9311
47 HSO 0.9308
48 FHC 0.9306
49 AKG 0.9306
50 PBA 0.9304
51 TYC 0.9302
52 PO6 0.9302
53 AHN 0.9293
54 TYE 0.9285
55 E0O 0.9284
56 33S 0.9284
57 S0W 0.9276
58 8OZ 0.9275
59 3QM 0.9272
60 TYL 0.9271
61 CLT 0.9270
62 4J8 0.9266
63 GVG 0.9265
64 M74 0.9264
65 6TZ 0.9260
66 AMQ 0.9255
67 1BN 0.9254
68 K7M 0.9254
69 R9J 0.9247
70 GLU 0.9244
71 3CR 0.9243
72 3QO 0.9243
73 QBS 0.9236
74 EDR 0.9228
75 P80 0.9224
76 L5V 0.9221
77 MEQ 0.9220
78 M45 0.9217
79 PH3 0.9217
80 PFF 0.9210
81 DIR 0.9209
82 EN1 0.9203
83 HGA 0.9201
84 FF3 0.9200
85 A09 0.9195
86 ONL 0.9193
87 HNH 0.9192
88 2HG 0.9184
89 HDH 0.9184
90 TSU 0.9183
91 JF6 0.9182
92 RMN 0.9181
93 4SX 0.9176
94 A29 0.9176
95 MUC 0.9175
96 M3H 0.9170
97 OOG 0.9170
98 6FZ 0.9168
99 F90 0.9165
100 9RH 0.9164
101 2C2 0.9163
102 APG 0.9162
103 RUY 0.9157
104 LNR 0.9155
105 3PG 0.9155
106 S2G 0.9153
107 7BC 0.9151
108 CFI 0.9151
109 YPN 0.9148
110 ISZ 0.9146
111 FK8 0.9143
112 J0Z 0.9142
113 4VY 0.9142
114 ARG 0.9142
115 PMF 0.9142
116 HL4 0.9140
117 3YP 0.9138
118 HC4 0.9136
119 Q06 0.9133
120 I38 0.9131
121 RLG 0.9131
122 RQD 0.9131
123 173 0.9131
124 1SA 0.9131
125 DAH 0.9127
126 MMS 0.9121
127 HNK 0.9118
128 A3M 0.9117
129 M6H 0.9116
130 5WZ 0.9116
131 GRO 0.9113
132 ICB 0.9108
133 BNF 0.9108
134 FTV 0.9104
135 AOS 0.9102
136 OHJ 0.9101
137 GWM 0.9101
138 KMH 0.9097
139 263 0.9097
140 SYM 0.9096
141 SAN 0.9092
142 O45 0.9089
143 9RW 0.9087
144 4HP 0.9087
145 LVD 0.9087
146 069 0.9087
147 N9J 0.9082
148 FUD 0.9080
149 LYS 0.9079
150 TZM 0.9079
151 Q9Z 0.9075
152 SYC 0.9073
153 TAG 0.9071
154 HWD 0.9068
155 FBM 0.9061
156 LSQ 0.9059
157 MNN 0.9058
158 1DJ 0.9057
159 DGL 0.9056
160 BHO 0.9055
161 LYN 0.9053
162 P7Y 0.9052
163 K6H 0.9052
164 GGL 0.9050
165 DHY 0.9049
166 F9P 0.9048
167 C53 0.9047
168 HA5 0.9043
169 DGN 0.9042
170 FCR 0.9039
171 Q02 0.9039
172 SD4 0.9035
173 3C4 0.9035
174 3LR 0.9031
175 ONH 0.9031
176 ALA ALA 0.9031
177 2FY 0.9030
178 CH8 0.9028
179 AVI 0.9027
180 N4B 0.9023
181 PAC 0.9020
182 Q03 0.9015
183 HXY 0.9014
184 G8M 0.9014
185 MAH 0.9013
186 HPS 0.9013
187 MES 0.9013
188 B85 0.9012
189 G3H 0.9011
190 152 0.9005
191 13P 0.9004
192 DHC 0.9001
193 HDL 0.9000
194 KDG 0.8999
195 9GB 0.8998
196 2IT 0.8997
197 PHI 0.8996
198 K34 0.8996
199 RAT 0.8995
200 GZQ 0.8994
201 1X4 0.8993
202 8GL 0.8992
203 3SL 0.8992
204 I3E 0.8991
205 Q04 0.8991
206 NPO 0.8990
207 AL0 0.8989
208 DXG 0.8988
209 SOR 0.8987
210 9ON 0.8985
211 NYL 0.8983
212 ORN 0.8983
213 SEP 0.8982
214 1VK 0.8980
215 7QS 0.8977
216 DAL DAL 0.8976
217 3VW 0.8976
218 MXN 0.8974
219 7Q1 0.8971
220 OSE 0.8970
221 GUA 0.8968
222 SAF 0.8961
223 PSJ 0.8960
224 RP3 0.8959
225 DZA 0.8958
226 DAR 0.8957
227 IAR 0.8957
228 GCO 0.8957
229 3HG 0.8956
230 TRP 0.8956
231 M5E 0.8956
232 CS2 0.8954
233 7C3 0.8953
234 PGH 0.8953
235 I2E 0.8952
236 7UC 0.8952
237 DLY 0.8951
238 1PS 0.8951
239 CFA 0.8950
240 EQW 0.8946
241 LDP 0.8942
242 AAS 0.8941
243 7OD 0.8941
244 269 0.8940
245 GLO 0.8938
246 4FA 0.8937
247 SOL 0.8936
248 E4P 0.8935
249 RBL 0.8935
250 LFC 0.8935
251 URQ 0.8934
252 TOH 0.8934
253 GLY PRO 0.8934
254 4PN 0.8933
255 CWD 0.8931
256 BWD 0.8930
257 QMP 0.8929
258 FWD 0.8929
259 2BX 0.8926
260 GNW 0.8925
261 ASC 0.8925
262 ALE 0.8923
263 XDE 0.8923
264 HL5 0.8923
265 IWD 0.8922
266 IYR 0.8921
267 XRX 0.8917
268 2FT 0.8915
269 LY0 0.8914
270 S8V 0.8914
271 FBS 0.8914
272 I1E 0.8914
273 15N 0.8913
274 OKG 0.8913
275 QY9 0.8912
276 OIA 0.8911
277 URP 0.8910
278 MF3 0.8910
279 DEW 0.8910
280 BPW 0.8907
281 ILO 0.8907
282 YRL 0.8905
283 AEG 0.8905
284 49F 0.8905
285 MLZ 0.8904
286 9W5 0.8903
287 264 0.8903
288 CIR 0.8903
289 URS 0.8902
290 PEP 0.8900
291 JZA 0.8899
292 QDK 0.8899
293 2B4 0.8899
294 61M 0.8896
295 NFM 0.8895
296 PBN 0.8894
297 M72 0.8891
298 SSC 0.8890
299 XUL 0.8889
300 CXP 0.8888
301 0JD 0.8888
302 258 0.8885
303 HG3 0.8884
304 LTT 0.8884
305 268 0.8883
306 XYL 0.8882
307 RBJ 0.8879
308 PRA 0.8877
309 MTL 0.8877
310 7UZ 0.8876
311 AEF 0.8873
312 XYH 0.8873
313 PC 0.8873
314 PZI 0.8873
315 N2Y 0.8872
316 6J5 0.8871
317 1GP 0.8870
318 9R5 0.8870
319 AC6 0.8869
320 YOF 0.8868
321 ZGL 0.8868
322 RNT 0.8867
323 LGT 0.8866
324 0QW 0.8865
325 3BU 0.8865
326 GLR 0.8864
327 XLS 0.8864
328 GGB 0.8863
329 E79 0.8861
330 0VT 0.8860
331 4JC 0.8859
332 G3P 0.8856
333 SV4 0.8853
334 DXP 0.8851
335 9YT 0.8849
336 7R4 0.8849
337 LPK 0.8848
338 RNS 0.8848
339 FOC 0.8845
340 GP9 0.8840
341 4ZD 0.8839
342 GAE 0.8838
343 ENW 0.8838
344 CUW 0.8836
345 GLY GLY 0.8830
346 C5A 0.8830
347 JX7 0.8829
348 ROR 0.8829
349 HPV 0.8828
350 BHH 0.8828
351 Y4L 0.8827
352 KYN 0.8821
353 BCU 0.8818
354 3H2 0.8815
355 9J3 0.8815
356 GRQ 0.8815
357 REL 0.8814
358 OEG 0.8814
359 JPQ 0.8813
360 XXG 0.8811
361 XI7 0.8809
362 1H1 0.8809
363 SDD 0.8807
364 TPO 0.8806
365 DTR 0.8806
366 PCS 0.8803
367 B09 0.8801
368 92K 0.8800
369 XXP 0.8799
370 MLT 0.8795
371 ATX 0.8793
372 4CF 0.8791
373 YIP 0.8791
374 3OM 0.8790
375 4TP 0.8789
376 FEH 0.8787
377 KTA 0.8785
378 PJL 0.8784
379 CLU 0.8784
380 2HC 0.8783
381 F06 0.8781
382 GVM 0.8779
383 6L6 0.8775
384 0A1 0.8774
385 0L1 0.8773
386 HPN 0.8771
387 PUE 0.8769
388 129 0.8767
389 5XA 0.8764
390 SQV 0.8762
391 4WK 0.8761
392 NNH 0.8760
393 6MW 0.8755
394 QH3 0.8753
395 LT1 0.8753
396 7N0 0.8750
397 ZZU 0.8745
398 PTU 0.8744
399 11C 0.8743
400 LLH 0.8742
401 5DL 0.8740
402 XQI 0.8739
403 MP5 0.8738
404 2D8 0.8738
405 36M 0.8737
406 API 0.8735
407 H4E 0.8733
408 256 0.8729
409 IPO 0.8727
410 SBK 0.8725
411 6JN 0.8724
412 791 0.8721
413 9BF 0.8719
414 ASN 0.8718
415 F98 0.8717
416 8SZ 0.8715
417 SME 0.8712
418 DLT 0.8711
419 HY1 0.8710
420 S7A 0.8707
421 SG3 0.8705
422 T2D 0.8703
423 T9G 0.8702
424 DEZ 0.8699
425 LL2 0.8698
426 DDU 0.8690
427 M3P 0.8687
428 SSB 0.8687
429 LUQ 0.8683
430 UA5 0.8682
431 2FM 0.8680
432 DHS 0.8677
433 2AS 0.8665
434 8U3 0.8663
435 ACA 0.8661
436 T03 0.8660
437 AFS 0.8659
438 HJ7 0.8656
439 1FD 0.8654
440 26P 0.8653
441 QIC 0.8651
442 BL0 0.8650
443 S24 0.8650
444 IVL 0.8649
445 LTL 0.8645
446 64Z 0.8642
447 27L 0.8637
448 HMS 0.8632
449 MHO 0.8631
450 RM1 0.8630
451 KDF 0.8626
452 8EW 0.8612
453 EYJ 0.8612
454 ENV 0.8605
455 ABF 0.8603
456 7Y3 0.8599
457 IXW 0.8597
458 NLE 0.8593
459 SER THR 0.8592
460 DS0 0.8589
461 XBT 0.8587
462 GLY ALA 0.8584
463 GTK 0.8582
464 6Q3 0.8579
465 3OL 0.8579
466 MET 0.8571
467 2JJ 0.8567
468 NSB 0.8547
469 54Z 0.8542
470 9VQ 0.8532
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6V7E; Ligand: QRA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6v7e.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 6V7E; Ligand: QRA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 6v7e.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 6V7E; Ligand: QRA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 6v7e.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 6V7E; Ligand: QRA; Similar sites found with APoc: 3
This union binding pocket(no: 4) in the query (biounit: 6v7e.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1WOG 16D 39.3443
2 1WOG 16D 39.3443
3 1WOG 16D 39.3443
Pocket No.: 5; Query (leader) PDB : 6V7E; Ligand: QRA; Similar sites found with APoc: 3
This union binding pocket(no: 5) in the query (biounit: 6v7e.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1WOG 16D 39.3443
2 1WOG 16D 39.3443
3 1WOG 16D 39.3443
Pocket No.: 6; Query (leader) PDB : 6V7E; Ligand: QRA; Similar sites found with APoc: 2
This union binding pocket(no: 6) in the query (biounit: 6v7e.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1WOG 16D 39.3443
2 1WOG 16D 39.3443
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