Receptor
PDB id Resolution Class Description Source Keywords
3k5u 2.35 Å EC: 2.7.11.1 IDENTIFICATION, SAR STUDIES AND X-RAY COCRYSTAL ANALYSIS OF FURANO-PYRIMIDINE AURORA KINASE A INHIBITOR HOMO SAPIENS AURORA KINASE INHIBITORS VIRTUAL SCREENING X-RAY CO-CRYSTAANALYSIS STRUCTURE-BASED DRUG DESIGN (SBDD) H-BONDING ATSITE CELL CYCLE CYTOSKELETON KINASE NUCLEOTIDE-BINDINGPHOSPHOPROTEIN SERINE/THREONINE-PROTEIN KINASE TRANSFERAS
Ref.: IDENTIFICATION, SAR STUDIES, AND X-RAY CO-CRYSTALLO ANALYSIS OF A NOVEL FURANOPYRIMIDINE AURORA KINASE INHIBITOR CHEMMEDCHEM V. 5 255 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PFQ A:1001;
Valid;
none;
ic50 = 309 nM
331.368 C20 H17 N3 O2 c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2WTV 2.4 Å EC: 2.7.11.1 AURORA-A INHIBITOR STRUCTURE HOMO SAPIENS KINASE CELL CYCLE TRANSFERASE PHOSPHOPROTEIN
Ref.: CRYSTAL STRUCTURE OF AN AURORA-A MUTANT THAT MIMICS AURORA-B BOUND TO MLN8054: INSIGHTS INTO SELECTIVITY AND DRUG DESIGN. BIOCHEM.J. V. 427 19 2010
Members (32)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 129 families.
1 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
2 4UZH ic50 = 9800 nM JVE C15 H13 F N4 O c1ccc(c(c1....
3 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
4 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
5 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
6 2C6E - HPM C28 H31 N7 O4 COc1cc2c(c....
7 3H0Y ic50 = 0.006 uM 48B C23 H17 Cl F N5 O2 c1ccc(c(c1....
8 4B0G ic50 = 0.015 uM VEK C19 H21 Br N8 O Cc1cc(no1)....
9 4JBP ic50 = 41 nM YPH C34 H36 N6 O4 c1ccc(cc1)....
10 3H10 - 97B C30 H25 Cl F2 N6 O CN1CCN(CC1....
11 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
12 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
13 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
14 1MQ4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
15 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
16 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
17 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
18 3DJ6 - AK6 C25 H24 N4 O3 S COc1ccc(cc....
19 2WQE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
20 4UYN ic50 = 2 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
21 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
22 3FDN ic50 = 0.033 uM MMH C21 H22 N6 O3 Cc1c(c([nH....
23 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
24 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
25 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
26 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
27 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
28 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
29 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
30 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
31 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
32 3K5U ic50 = 309 nM PFQ C20 H17 N3 O2 c1ccc(cc1)....
70% Homology Family (32)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 94 families.
1 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
2 4UZH ic50 = 9800 nM JVE C15 H13 F N4 O c1ccc(c(c1....
3 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
4 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
5 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
6 2C6E - HPM C28 H31 N7 O4 COc1cc2c(c....
7 3H0Y ic50 = 0.006 uM 48B C23 H17 Cl F N5 O2 c1ccc(c(c1....
8 4B0G ic50 = 0.015 uM VEK C19 H21 Br N8 O Cc1cc(no1)....
9 4JBP ic50 = 41 nM YPH C34 H36 N6 O4 c1ccc(cc1)....
10 3H10 - 97B C30 H25 Cl F2 N6 O CN1CCN(CC1....
11 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
12 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
13 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
14 1MQ4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
15 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
16 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
17 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
18 3DJ6 - AK6 C25 H24 N4 O3 S COc1ccc(cc....
19 2WQE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
20 4UYN ic50 = 2 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
21 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
22 3FDN ic50 = 0.033 uM MMH C21 H22 N6 O3 Cc1c(c([nH....
23 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
24 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
25 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
26 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
27 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
28 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
29 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
30 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
31 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
32 3K5U ic50 = 309 nM PFQ C20 H17 N3 O2 c1ccc(cc1)....
50% Homology Family (385)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 68 families.
1 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
2 4UZH ic50 = 9800 nM JVE C15 H13 F N4 O c1ccc(c(c1....
3 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
4 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
5 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
6 2C6E - HPM C28 H31 N7 O4 COc1cc2c(c....
7 3H0Y ic50 = 0.006 uM 48B C23 H17 Cl F N5 O2 c1ccc(c(c1....
8 4B0G ic50 = 0.015 uM VEK C19 H21 Br N8 O Cc1cc(no1)....
9 4JBP ic50 = 41 nM YPH C34 H36 N6 O4 c1ccc(cc1)....
10 3H10 - 97B C30 H25 Cl F2 N6 O CN1CCN(CC1....
11 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
12 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
13 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
14 1MQ4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
15 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
16 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
17 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
18 3DJ6 - AK6 C25 H24 N4 O3 S COc1ccc(cc....
19 2WQE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
20 4UYN ic50 = 2 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
21 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
22 3FDN ic50 = 0.033 uM MMH C21 H22 N6 O3 Cc1c(c([nH....
23 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
24 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
25 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
26 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
27 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
28 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
29 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
30 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
31 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
32 3K5U ic50 = 309 nM PFQ C20 H17 N3 O2 c1ccc(cc1)....
33 1JSV - U55 C10 H11 N5 O2 S c1cc(ccc1N....
34 1E1V Ki = 12 uM CMG C12 H17 N5 O c1[nH]c2c(....
35 1OIQ ic50 = 2.9 uM HDU C14 H13 N5 O Cc1c(n2ccc....
36 2VV9 ic50 = 0.017 uM IM9 C23 H29 N7 O2 Cc1ncc(n1C....
37 2W17 ic50 = 0.002 uM I19 C24 H30 F N7 O Cc1ncc(n1C....
38 2VTP ic50 = 0.003 uM LZ9 C17 H11 F3 N4 O2 c1cc(c(c(c....
39 1JVP ic50 = 1.6 uM LIG C15 H11 N3 c1ccc-2c(c....
40 1FVT - 106 C14 H9 Br N4 O3 S c1cc(ccc1/....
41 4KD1 - 1QK C21 H29 N6 O2 CCc1cnn2c1....
42 2BTS ic50 = 20 nM U32 C12 H15 N3 O2 S2 CC(C)c1cnc....
43 3LE6 ic50 = 0.035 uM 2BZ C17 H10 Cl N5 O2 Cc1c-2nc(c....
44 2VTI ic50 = 0.66 uM LZ3 C14 H12 N4 O3 S c1ccc2c(c1....
45 3LFS Ki = 2.5 uM A07 C17 H16 Cl N3 O CCCC(=O)Nc....
46 1PXI - CK1 C8 H5 Cl2 N3 S c1cnc(nc1c....
47 1URW ic50 < 0.003 uM I1P C21 H24 N8 O2 S CN(C)CCCNS....
48 4LYN - 1YG C20 H23 N3 O2 S2 C[C@@H](c1....
49 1YKR ic50 = 0.56 uM 628 C20 H14 Cl2 N4 O3 S c1cc(c(c(c....
50 1PXN Ki ~ 0.32 uM CK6 C15 H15 N5 O S Cc1c(sc(n1....
51 1CKP - PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
52 1KE6 ic50 = 5.7 nM LS2 C17 H15 N5 O3 S2 CNS(=O)(=O....
53 2C6K ic50 = 0.73 uM DT2 C17 H21 N7 O2 S c1cc(ccc1N....
54 2R3Q - 5SC C19 H16 Br N5 O Cc1ccccc1c....
55 2R3J ic50 = 10 nM SCJ C18 H14 Br N5 c1ccc(cc1)....
56 3IG7 ic50 = 9 nM EFP C18 H22 N4 O3 CC(=O)NC1C....
57 2VTS ic50 = 0.03 uM LZC C16 H23 N7 CC(C)Nc1cc....
58 1P2A ic50 = 12 nM 5BN C17 H15 F N4 O c1cc([nH]c....
59 2BHE ic50 = 1 uM BRY C16 H9 Br N2 O2 c1ccc2c(c1....
60 3UNK ic50 = 15 uM 0BY C17 H13 Cl N4 O2 c1ccc(c(c1....
61 1OIT ic50 < 0.003 uM HDT C17 H14 N6 O2 S c1ccn2c(c1....
62 2VTQ ic50 = 0.14 uM LZA C16 H17 F2 N5 O2 c1cc(c(c(c....
63 3NS9 ic50 = 0.003 uM NS9 C20 H27 N5 O3 CC(C)c1cnn....
64 2C68 ic50 = 1.8 uM CT6 C18 H15 Br N5 c1cc(cc(c1....
65 3TIZ - 3TI C17 H13 N O2 c1ccc2c(c1....
66 3PXY ic50 = 5.9 uM JWS C10 H11 N5 O2 COc1ccc(c(....
67 1H01 ic50 = 22 uM FAL C21 H23 Cl2 N5 O2 CN(C)C[C@H....
68 2EXM - ZIP C10 H13 N5 CC(=CCNc1c....
69 4BGH ic50 = 4 nM 3I6 C13 H16 Br N5 O3 S C[C@H](CO)....
70 2R3F ic50 = 500 nM SC8 C18 H13 Cl2 N5 c1cc(c(c(c....
71 2R3M ic50 = 10 nM SCX C19 H17 F2 N7 CCc1cnn2c1....
72 1GII - 1PU C17 H16 N4 O2 c1ccnc(c1)....
73 2R64 ic50 = 0.03 uM 740 C23 H27 N5 O3 S c1cc(ccc1C....
74 2C6O - 4SP C18 H22 N6 O3 S c1cc(ccc1N....
75 1V1K Ki = 35 uM 3FP C22 H23 F4 N5 O2 CN(C)C[C@H....
76 2VTJ ic50 = 1.9 uM LZ4 C10 H9 Cl N4 O2 S c1cc(ccc1N....
77 2C6L ic50 = 0.27 uM DT4 C17 H22 N8 O2 S c1cc(ccc1N....
78 2W06 - FRV C18 H20 N6 O2 S Cc1ncc(n1C....
79 3EZV - EZV C25 H25 N7 CN1CCN(CC1....
80 4EZ7 - STU C28 H26 N4 O3 C[C@@]12[C....
81 3PXZ Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
82 1W0X - OLO C15 H18 N6 O Cn1cnc2c1n....
83 2XMY Ki = 0.11 nM CDK C18 H21 N5 O4 S2 CC1=C(SC(=....
84 2UZO ic50 = 18 uM C62 C14 H10 N2 O5 S2 c1cc(ccc1c....
85 2VTT ic50 = 0.044 uM LZD C16 H17 F2 N5 O2 c1cc(c(c(c....
86 1KE7 ic50 = 8.9 nM LS3 C20 H15 N3 O4 S c1cc2c(cc1....
87 2VU3 ic50 = 0.047 uM LZE C16 H17 Cl2 N5 O2 c1cc(c(c(c....
88 2B54 - D05 C20 H15 Cl3 N4 O3 CCc1c2c(n(....
89 1DM2 - HMD C11 H10 Br N5 O2 C1CNC(=O)C....
90 1DI8 ic50 = 1 uM DTQ C16 H15 N3 O3 COc1cc2c(c....
91 1GZ8 - MBP C10 H13 N5 O2 CC(C)C(=O)....
92 3PY0 ic50 = 0.13 uM SU9 C13 H11 N3 O2 COc1ccc2c(....
93 2VTR ic50 = 1.5 uM LZB C10 H10 Cl N5 CC(C)Nc1cc....
94 1E1X Ki = 1.3 uM NW1 C11 H17 N5 O2 C1CCC(CC1)....
95 1GIJ - 2PU C19 H22 N6 O2 c1cc2c(c(c....
96 3UNJ ic50 = 11 uM 0BX C17 H14 N4 O2 c1ccc(cc1)....
97 2A0C - CK9 C19 H26 N6 O2 CC[C@H](CO....
98 3TIY - TIY C11 H8 O5 c1c2c(c(c(....
99 2R3I ic50 = 1000 nM SCF C18 H14 F N5 c1ccc(c(c1....
100 2R3P ic50 = 900 nM 3SC C19 H12 Cl2 N6 S c1cc(c(c(c....
101 1KE8 ic50 = 1000 nM LS4 C18 H14 N4 O3 S2 c1ccc2c(c1....
102 2C6I ic50 = 11 uM DT1 C18 H22 N6 O3 S c1cc(ccc1N....
103 1VYZ ic50 = 290 nM N5B C13 H13 N3 O c1ccc(cc1)....
104 3WBL ic50 = 23 uM PDY C20 H26 N6 O CCOc1ccc(c....
105 1PXP Ki ~ 0.22 uM CK8 C17 H19 N5 S Cc1c(sc(n1....
106 4RJ3 ic50 = 93 nM 3QS C22 H28 N6 O COC1CCN(CC....
107 2VTN ic50 = 0.85 uM LZ7 C12 H11 F N4 O2 CC(=O)Nc1c....
108 1AQ1 - STU C28 H26 N4 O3 C[C@@]12[C....
109 2UZN ic50 = 0.03 uM C96 C15 H13 N3 O4 S2 [H]/N=C/1N....
110 2B55 ic50 = 96 nM D31 C24 H31 N5 O2 c1cc-2c(c(....
111 2C6M ic50 = 0.35 uM DT5 C17 H20 N6 O3 S c1cc(ccc1N....
112 3PJ8 - 404 C19 H26 N6 O CC[C@H](CO....
113 3LFQ - A28 C17 H15 F2 N3 O CCCC(=O)Nc....
114 2R3L ic50 = 100 nM SCW C18 H14 Br N5 c1ccc(cc1)....
115 2W05 ic50 = 0.001 uM FRT C20 H26 N6 O3 S Cc1ncc(n1C....
116 1H08 - BYP BWP n/a n/a
117 2XNB Ki = 149 nM Y8L C19 H22 N6 O S CC1=C(SC(=....
118 1HCK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
119 1B38 Kd = 0.254 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
120 2B52 ic50 = 8 nM D42 C21 H23 N7 O2 S Cc1c(sc(n1....
121 1PXL - CK4 C16 H13 F3 N4 S Cc1c(sc(n1....
122 2R3H ic50 = 20000 nM SCE C13 H13 N5 Cc1cnc2n1c....
123 3LFN Ki = 3160 nM A27 C23 H21 N3 O2 CCCC(=O)Nc....
124 3S2P ic50 = 0.068 uM PMU C17 H22 N4 O3 CC(C)c1cc(....
125 2R3O ic50 = 600 nM 2SC C19 H17 N5 O c1ccc(cc1)....
126 3IGG ic50 = 95 nM EFQ C16 H19 N3 O3 COc1ccc(cc....
127 1R78 ic50 = 3 nM FMD C20 H20 F N3 O4 C[C@H]([C@....
128 2FVD Ki = 0.003 uM LIA C18 H21 F2 N5 O4 S COc1ccc(c(....
129 2VTL ic50 = 97 uM LZ5 C10 H9 N3 O c1ccc(cc1)....
130 3PY1 Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
131 1KE9 ic50 = 660 nM LS5 C16 H15 N5 O3 S c1ccc2c(c1....
132 2A4L ic50 = 0.4 uM RRC C19 H26 N6 O CC[C@H](CO....
133 1Y8Y ic50 = 2 uM CT7 C13 H11 Cl N4 O2 S CS(=O)(=O)....
134 1OIR ic50 = 0.032 uM HDY C23 H26 N6 O2 Cc1c(n2ccc....
135 1PXJ - CK2 C9 H10 N4 S Cc1c(sc(n1....
136 2VTO ic50 = 0.14 uM LZ8 C17 H13 F N4 O2 c1ccc(cc1)....
137 1PYE ic50 = 0.32 uM PM1 C21 H13 F2 N3 O2 c1ccc(cc1)....
138 2BTR ic50 = 95 nM U73 C13 H15 N3 O S CC(C)C1=CN....
139 2VTA ic50 = 185 uM LZ1 C7 H6 N2 c1ccc2c(c1....
140 4EZ3 - 0S0 C11 H10 N4 O4 S c1cc(ccc1/....
141 3EZR - EZR C26 H27 N7 O CN1CCN(CC1....
142 3ULI ic50 = 0.07 uM 1N3 C21 H25 Br N6 O2 COc1ccc(cc....
143 2DS1 ic50 = 6.4 nM 1CD C22 H21 N5 O3 C[C@@H]1C[....
144 1H07 ic50 = 3 uM MFP C24 H27 Br N6 O2 Cc1ccc(c(c....
145 2B53 ic50 = 0.6 uM D23 C19 H19 F3 N4 CC(C)(C)Nc....
146 2DUV ic50 = 0.087 uM 371 C19 H17 N O7 S Cc1cc2c(c(....
147 2VTH ic50 = 120 uM LZ2 C10 H9 N O3 S c1cc2c(ccc....
148 1KE5 ic50 = 560 nM LS1 C16 H15 N3 O3 S CNS(=O)(=O....
149 3FZ1 - B98 C13 H15 N3 O2 S COc1ccc2c(....
150 1WCC ic50 = 350 uM CIG C4 H4 Cl N3 c1c(nc(cn1....
151 4ACM Ki = 210 nM 7YG C20 H23 N7 O3 S CN(C)CCNS(....
152 2C5Y ic50 = 0.25 uM MTW C19 H15 N7 O2 c1cc(cc(c1....
153 1PXO Ki = 2 nM CK7 C14 H12 N6 O2 S Cc1c(sc(n1....
154 1H00 ic50 = 38 uM FAP C21 H23 F2 N5 O2 CN(C)C[C@@....
155 2R3R - 6SC C18 H14 Br N5 c1ccc(cc1)....
156 2R3K ic50 = 100 nM SCQ C18 H14 Br N5 c1ccc(cc1)....
157 2V0D - C53 C9 H7 N3 O S [H]/N=C1/N....
158 1B39 Kd = 0.12 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
159 2W1H ic50 = 0.052 uM L0F C17 H13 N5 O c1ccc(cc1)....
160 1Y91 ic50 = 0.059 uM CT9 C23 H33 N7 O2 S CC(C)c1cnn....
161 2ZJW ic50 = 0.04 uM REF C14 H6 O8 c1c2c-3c(c....
162 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
163 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
164 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
165 2E9O ic50 = 20 nM A58 C25 H27 N3 O2 CC1CCC(CC1....
166 2WMQ - ZYQ C9 H11 N3 O2 S CC(=O)Nc1n....
167 2C3J Ki = 0.659 uM DBQ C11 H11 N5 O2 c1c[nH]c2c....
168 2YM7 ic50 = 0.13 uM YM7 C15 H18 N8 c1c(ncnc1N....
169 2X8I ic50 = 0.19 uM X8I C17 H13 N3 O2 CC1=CC2=NN....
170 2YDJ ic50 = 0.005 uM YDJ C17 H19 F N4 O2 S c1cc(cc(c1....
171 4QYE ic50 = 1.2 uM 3DL C17 H12 N2 O3 c1cc(cc(c1....
172 2BRO ic50 = 1.4 uM DF2 C21 H20 N4 O2 c1ccc(cc1)....
173 2BRG ic50 = 6.1 uM DFY C21 H19 N3 O2 CN(CCO)c1c....
174 2YM5 ic50 = 0.43 uM YM5 C18 H21 N5 O2 c1cc(cc(c1....
175 4HYH ic50 = 1 nM 1AM C22 H22 N6 O3 S COc1ccc2c(....
176 2CGU ic50 = 13.4 uM 3A3 C17 H13 N O7 c1cc-2c(cc....
177 1NVS Ki = 15 nM UCM C24 H15 N3 O3 c1ccc2c(c1....
178 2YDK ic50 = 0.007 uM YDK C17 H20 N4 O2 S c1ccc(cc1)....
179 3OT3 ic50 = 0.005 uM 22K C16 H20 Br N7 Cn1cc(cn1)....
180 2WMR ic50 = 52 uM ZYR C10 H10 N2 O S C1CCc2c(c3....
181 3PA5 ic50 = 2 nM C73 C17 H19 Cl N4 O2 S c1cc(ccc1c....
182 2WMV ic50 = 9.2 uM ZYV C10 H14 N6 O c1[nH]c2c(....
183 2BRH ic50 = 22 uM DFW C20 H15 N3 O3 c1ccc(cc1)....
184 1NVR Ki = 7.8 nM STU C28 H26 N4 O3 C[C@@]12[C....
185 2CGX ic50 = 15.6 uM 3D3 C7 H8 N6 O S c1nc(c2c(n....
186 3OT8 ic50 = 0.009 uM MI5 C19 H22 N8 S Cc1cc(sn1)....
187 2YM4 ic50 = 1.5 uM 4YM C21 H22 N6 O3 CCOC(=O)c1....
188 4HYI ic50 = 2 nM 1AO C21 H20 N6 O S c1ccc2c(c1....
189 4QYF - 3DV C17 H13 N3 O3 c1cc(cc(c1....
190 3JVS Ki = 0.146 uM AGY C22 H22 N4 O4 CC(C)(C)c1....
191 2WMW ic50 = 0.39 uM ZYW C11 H14 Br N5 O c1c2c(c(cn....
192 2BR1 Ki = 7.2 uM PFP C22 H21 N3 O4 COc1ccc(cc....
193 2XF0 ic50 = 30 uM 4UB C15 H11 N5 c1ccc(cc1)....
194 2C3L Ki = 0.026 uM IDZ C14 H10 N4 c1ccc2c(c1....
195 2YM6 ic50 = 0.88 uM YM6 C14 H16 N6 O c1cncc2c1c....
196 2X8E ic50 = 0.014 uM X8E C16 H12 N4 O CC1=CC2=NN....
197 4QYG ic50 = 0.0041 uM 3DW C22 H21 N5 O2 CN1CCN(CC1....
198 2X8D ic50 = 0.8 uM X8D C11 H9 N3 O CC1=CC2=NN....
199 2YEX ic50 = 0.0001 uM YEX C15 H12 N4 O CC1=CC2=NN....
200 2BRM Ki = 1.3 uM DFZ C20 H18 N4 O c1ccc(cc1)....
201 2XEZ ic50 = 1.5 uM XEZ C12 H9 N7 c1c[nH]nc1....
202 1NVQ Ki = 5.6 nM UCN C28 H26 N4 O4 C[C@@]12[C....
203 3PA4 ic50 = 3 nM C72 C19 H19 Cl N4 O S c1cc(ccc1c....
204 2E9N ic50 = 6.2 nM 76A C29 H27 N3 O3 c1cc(ccc1c....
205 2YM3 ic50 = 1.2 uM YM3 C14 H19 N5 O3 CCOC(=O)c1....
206 2YDI - YDI C16 H20 N4 O3 S CN(C)CCOc1....
207 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
208 1JKL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
209 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
210 3F5G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
211 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
212 1P4F - DRG C12 H11 N3 c1ccc-2c(c....
213 4TXC Kd = 0.24 uM 38G C24 H27 N5 O3 CN(C)CCN[C....
214 2YAK ic50 = 2 nM OSV C27 H31 F N4 O3 Ru S4 CC(C)Oc1cc....
215 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
216 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
217 3SHE - I85 C24 H22 F3 N5 O2 c1cc(cc(c1....
218 3R1N - 05B C22 H21 N5 O3 c1cc2c(cc1....
219 4AU8 ic50 = 551 nM Z3R C11 H8 N2 O2 S3 c1ccc2c(c1....
220 1REJ Ki = 5 nM B1L C20 H22 N2 O5 c1cc(ccc1C....
221 3BWJ ic50 = 2.6 uM ARX C28 H47 N15 O7 [H]/N=C(N)....
222 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
223 3AGL Ki = 16 nM A03 C37 H63 N17 O9 [H]/N=C(N)....
224 1RE8 Ki = 0.3 nM BD2 C27 H26 N2 O6 c1ccc(c(c1....
225 2VZ6 - FEF C20 H19 N3 O4 c1ccc2c(c1....
226 2Z7Q - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
227 2Z7R ic50 = 3 nM STU C28 H26 N4 O3 C[C@@]12[C....
228 3QD4 ic50 = 1e-08 M 3Q6 C22 H30 N8 O2 C[C@@H]1C[....
229 1Z5M ic50 = 30 nM LI8 C23 H31 Br N8 O3 CC(C)(C(=O....
230 3RCJ ic50 = 0.8 uM 3RC C16 H13 N5 c1ccc(cc1)....
231 2PE0 - 39Z C14 H12 N2 O2 CC(c1ccc[n....
232 4CT2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
233 3QD0 ic50 = 1e-08 M 3Q4 C24 H26 N8 O C[C@@H]1CC....
234 3ORZ - BI4 C27 H26 N4 O2 C[N@]1CCC[....
235 3HRC - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
236 3ION ic50 = 8 nM 8H1 C28 H27 N5 O3 COc1cc2c3c....
237 2XCH ic50 = 374 nM CKG C22 H25 N7 O c1c2c(nc(n....
238 4AW0 - MJF C18 H15 Cl O5 c1ccc(cc1)....
239 1UU7 ic50 = 14 uM BI2 C27 H26 N4 O2 C[N@@]1CCC....
240 3OTU - BI4 C27 H26 N4 O2 C[N@]1CCC[....
241 3HRF Kd = 10.3 uM P47 C17 H15 Cl O2 c1ccc(cc1)....
242 3QCS ic50 = 1e-08 M 3Q1 C15 H17 N7 O c1cc2c(cc1....
243 3QCX ic50 = 1e-08 M 3Q2 C16 H19 N7 O C[C@@H]1CO....
244 1UU3 ic50 = 0.75 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
245 1H1W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
246 3QC4 ic50 = 0.002 uM MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
247 4AW1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
248 3QCY ic50 = 1e-08 M 3Q3 C22 H22 N8 O2 c1ccc(cc1)....
249 1UU8 ic50 = 9 uM BI1 C25 H24 N4 O2 CN(C)CCCn1....
250 4CT1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
251 2PE2 - 464 C28 H30 N6 O3 c1cc(cc(c1....
252 3H9O ic50 = 70 nM 9BD C19 H19 N5 O3 COCCOc1cc2....
253 4A07 - AZ7 C17 H13 Cl3 N2 O2 c1cc(ccc1[....
254 4KS7 - X4Z C25 H28 N8 O S Cc1nc2ccsc....
255 4KS8 - B49 C22 H27 F N4 O2 CCN(CC)CCN....
256 4DGO ic50 = 0.57 uM 0JW C10 H10 N2 O3 c1cc(c(cc1....
257 4DGM ic50 = 1.2 uM AGI C15 H10 O5 c1cc(ccc1C....
258 2PVJ Ki = 0.005 uM P44 C19 H21 N7 c1ccc(cc1)....
259 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
260 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
261 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
262 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
263 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
264 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
265 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
266 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
267 3SLS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
268 4AUA ic50 = 7.2 uM 4AU C12 H9 N3 O c1ccc2c(c1....
269 2QHN ic50 = 980 nM 582 C13 H13 N3 O CCN1c2cccc....
270 3TKI ic50 = 0.05 nM S25 C20 H23 N7 O2 S c1cnc(cc1N....
271 2HXQ ic50 = 144 nM 373 C24 H26 N4 O c1ccc2c(c1....
272 2QHM ic50 = 660 nM 7CS C16 H19 N3 O2 CN1[C@H]2C....
273 2R0U ic50 = 1 nM M54 C25 H22 N4 O2 c1cc(cc(c1....
274 3TKH ic50 = 47 nM 07S C23 H27 N7 O2 S c1cc(cnc1)....
275 2HXL ic50 = 12 nM 422 C23 H24 N6 c1cc2c(cc1....
276 2HOG ic50 = 0.3 nM 710 C24 H25 N7 O c1cc2c(cc1....
277 2XK6 - EQH C18 H21 N3 O2 S c1csc(c1C2....
278 2WQO - VGK C21 H20 N2 O5 COc1cc(cc(....
279 2XKE ic50 = 4.2 uM WI2 C17 H20 N4 O3 COc1cccc(c....
280 2XNN - 430 C21 H16 F3 N3 O2 S C[C@H](c1c....
281 2XK7 ic50 = 1.5 uM 30E C21 H28 N4 O5 CC[C@H]1C[....
282 4EQU - G6I C30 H24 F3 N7 O2 Cc1ccc(cc1....
283 2J7T - 274 C28 H30 Cl N5 O4 S Cc1c([nH]c....
284 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
285 3D0E ic50 = 13 nM G93 C21 H27 N7 O3 CCn1c2c(cn....
286 2JDO ic50 = 0.23 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
287 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
288 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
289 1O6K - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
290 3E88 Ki = 2 nM G96 C24 H27 N7 O3 CCn1c2cc(n....
291 4OBQ ic50 = 0.065 uM 2QT C20 H20 F N5 O c1cc2c(cc1....
292 4U43 Kd = 48 uM 3D8 C11 H9 N5 c1cc(cnc1)....
293 4OBP ic50 = 0.017 uM 2QU C12 H8 F N5 c1cc(nc2c1....
294 4OBO ic50 = 0.077 uM 2QV C14 H10 Cl N3 c1cc(cc(c1....
295 4U44 ic50 = 0.008 uM 3D9 C17 H13 N5 c1ccc(cc1)....
296 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
297 4NW5 ic50 = 0.02 uM 2NR C23 H21 F N2 O5 COc1cccc(c....
298 4EL9 - AFE C21 H20 O10 C[C@H]1[C@....
299 4NUS ic50 = 0.005 uM 2NK C22 H21 F2 N3 O CN1CCN(CC1....
300 4NW6 ic50 = 0.004 uM 2NS C23 H20 N4 O4 COc1cc(cc(....
301 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
302 2YIT ic50 = 0.29 nM YIT C21 H24 N6 O2 CCC/C(=NNC....
303 2W0J ic50 = 240 nM ZAT C19 H24 N10 O [H]/N=C(N)....
304 2W7X ic50 = 138 nM D1A C18 H17 N7 O3 [H]/N=C(N)....
305 4A9U - A9U C27 H28 N4 O2 c1ccc(cc1)....
306 2XK9 ic50 = 0.03 nM XK9 C18 H17 N7 O4 C/C(=NNC(=....
307 2YCS ic50 = 1.36 nM NXP C18 H18 N6 O C/C(=NNC(=....
308 2YCF ic50 = 0.7 nM YCF C19 H24 N10 O3 [H]/N=C(N/....
309 2WTI ic50 = 0.092 uM WTI C18 H15 N3 O3 S c1cc(ccc1c....
310 2YIR ic50 = 0.17 nM YIR C20 H19 N7 O3 [H]/N=C(N)....
311 2XBJ ic50 = 0.86 uM XBJ C23 H27 F N4 O4 CC(C)([C@@....
312 4BDI ic50 = 227.7 uM HAU C14 H19 N3 O2 Cc1ccc(nc1....
313 2XM9 ic50 = 0.009 uM LWH C21 H20 N6 O c1ccc2c(c1....
314 2YCR ic50 = 69.6 nM HCW C23 H28 N10 O C/C(=NNC1=....
315 2YIQ ic50 = 12.67 nM YIQ C20 H19 N7 O C/C(=NNC(=....
316 2WTJ ic50 = 0.7 uM WTJ C16 H20 N4 O3 S CN(C)CCNC(....
317 2CN5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
318 4FII - ARG PRO LYS PRO LEU VAL ASP PRO n/a n/a
319 4JDK - ARG ARG ARG ARG SER TRP TYR n/a n/a
320 4JDI - ARG ARG ARG ARG SER TRP TYR n/a n/a
321 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
322 3A7J - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
323 3A7I - ADE C5 H5 N5 c1[nH]c2c(....
324 1U5R - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
325 3EQC - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
326 3EQH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
327 3EQI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
328 2J51 - DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
329 2UV2 - GVD C22 H19 N7 c1ccc2c(c1....
330 2JFL - DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
331 4FG9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
332 4FG8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
333 4JQE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
334 1QL6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
335 1PHK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
336 2F57 - 23D C19 H24 Cl N7 CCn1cnc2c1....
337 1XJD Ki = 0.33 nM STU C28 H26 N4 O3 C[C@@]12[C....
338 3A62 - STU C28 H26 N4 O3 C[C@@]12[C....
339 3WF9 ic50 = 567 nM FS7 C24 H25 N3 O5 S C[C@H]1CCc....
340 3WF8 ic50 = 232 nM F76 C23 H23 N3 O5 S c1ccc2c(c1....
341 4L3L - 5FI C19 H21 F3 N6 CCc1cncnc1....
342 3WE4 ic50 = 15 nM 5FI C19 H21 F3 N6 CCc1cncnc1....
343 3WF7 ic50 = 206 nM FS9 C18 H17 F3 N6 O c1cc(cc(c1....
344 4L3J - 5FI C19 H21 F3 N6 CCc1cncnc1....
345 3WF6 ic50 = 33 nM FZ9 C18 H16 N6 c1ccc2c(c1....
346 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
347 2VN9 - GVD C22 H19 N7 c1ccc2c(c1....
348 4EJN ic50 = 0.005 uM 0R4 C33 H26 F N7 O2 CC(=O)Nc1c....
349 2V7O - DRN C25 H23 N5 O2 S [H]/N=C(/N....
350 2WEI ic50 = 3.4 nM VGG C17 H21 N5 Cc1cccc(c1....
351 3CQW ic50 = 42 nM CQW C12 H11 Cl N6 c1c(c2c([n....
352 3MV5 ic50 = 180 nM XFE C11 H15 N5 Cc1c[nH]c2....
353 3QKL - SMR C29 H40 N4 O5 S CCOCC[N@@]....
354 4GV1 ic50 = 3 nM 0XZ C21 H25 Cl N6 O2 c1cc(ccc1[....
355 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
356 3MVH ic50 = 0.5 nM WFE C20 H22 F2 N6 O CCc1c[nH]c....
357 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
358 3Q53 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
359 4O0R Ki = 0.036 uM X4Z C25 H28 N8 O S Cc1nc2ccsc....
360 4EQC ic50 = 0.008 uM XR1 C29 H28 Cl N7 O S CCN1c2c(cn....
361 3FY0 ic50 = 1090 nM DW1 C23 H13 N3 O4 Ru C1=CC(C=C1....
362 3FXZ ic50 = 130 nM FLL C30 H18 Cl F N5 O4 Ru c1ccc(cc1)....
363 3Q4Z - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
364 3GC0 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
365 3MFU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
366 3C0I - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
367 3MFS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
368 3MFR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
369 3TXO ic50 = 9 nM 07U C17 H19 N5 CC(C)(CNc1....
370 4OTH ic50 = 9 nM DRN C25 H23 N5 O2 S [H]/N=C(/N....
371 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
372 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
373 1V0P ic50 = 0.13 uM PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
374 1V0O ic50 = 5.5 uM INR C16 H10 N2 O5 S c1ccc2c(c1....
375 4NJD ic50 = 0.79 uM NJD C21 H20 N8 O COc1nc(nc(....
376 4APP Ki = 0.064 uM N53 C33 H36 N6 O3 CC1(c2c(c(....
377 4O0X Ki = 0.068 uM 2OQ C19 H20 N6 O Cc1nc2ccc(....
378 2X4Z Ki = 18.7 nM X4Z C25 H28 N8 O S Cc1nc2ccsc....
379 4O0Y Ki = 0.06 uM 2OO C17 H19 N7 O CCNc1nc2cc....
380 2CDZ - 23D C19 H24 Cl N7 CCn1cnc2c1....
381 3A8W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
382 3AQV - TAK C24 H25 N5 O c1cc(ccc1c....
383 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
384 2YAB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
385 2YAA - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PFQ; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 PFQ 1 1
2 DFW 0.69697 0.892857
3 PFP 0.681818 0.883333
4 DFY 0.513889 0.819672
5 DFZ 0.434211 0.851852
6 547 0.428571 0.68254
Similar Binding Sites
Pocket no: 1; Query (leader) PDB : 2WTV; Ligand: ZZL; Similar sites found: 567
This union binding pocket (no: 1) in the query (biounit: 2wtv.bio1) has 52 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 2WTV ZZL 2.166e-23 1
2 3RWP ABQ 9.565e-08 0.51894
3 2GU8 796 2.377e-07 0.51171
4 2XMY CDK 4.014e-07 0.4977
5 2BPM 529 1.68e-07 0.49551
6 4MXO DB8 8.575e-08 0.49244
7 4C2V YJA 1.949e-09 0.49212
8 3MVH GLY 4.515e-07 0.48618
9 3BZ3 YAM 2.131e-07 0.47799
10 1PME SB2 3.317e-07 0.47387
11 3IOK 1P6 3.014e-07 0.47171
12 2JDR GLY 3.173e-06 0.47057
13 4F65 0S9 1.897e-07 0.4704
14 4NWM 2P5 9.012e-07 0.46965
15 4WHZ 3NL 8.207e-06 0.4674
16 3LQ8 88Z 1.497e-06 0.4646
17 2JLD AG1 5.363e-08 0.46109
18 1RE8 BD2 3.421e-06 0.46034
19 1OUK 084 7.342e-05 0.45956
20 2YAK OSV 5.832e-09 0.45932
21 4EQC XR1 6.064e-08 0.45691
22 4F4P 0SB 1.062e-06 0.45303
23 3THB 3TA 2.095e-07 0.44797
24 3E5A VX6 1.113e-08 0.44747
25 3KRL KRL 1.166e-08 0.44602
26 2XB7 GUI 4.48e-07 0.44563
27 4P5Z Q7M 5.909e-06 0.44512
28 3E8N ATP 5.71e-06 0.44193
29 4GJ3 0XP 4.712e-08 0.44177
30 3V8T 477 3.186e-06 0.43922
31 2X4Z X4Z 1.944e-07 0.438
32 4BKY 82B 1.967e-09 0.43649
33 4NW6 2NS 2.899e-07 0.43623
34 1XKK FMM 7.052e-07 0.43558
35 3PVW QRX 6.335e-08 0.43552
36 2XNM WGZ 4.794e-08 0.43526
37 3RI1 3RH 7.579e-09 0.43336
38 4AG8 AXI 8.115e-07 0.43098
39 4L3L 5FI 1.066e-08 0.43019
40 3LXK MI1 5.562e-07 0.42749
41 2OFV 242 4.386e-06 0.42531
42 3KF4 B90 2.069e-05 0.42348
43 4E93 GUI 1.068e-05 0.42294
44 3SXF BK5 2.806e-06 0.41984
45 2Z7R STU 1.739e-08 0.41799
46 3VHE 42Q 9.784e-07 0.41697
47 4NM5 ADP 2.007e-05 0.41617
48 3NW7 LGV 1.011e-05 0.41438
49 3EKK GS2 4.347e-08 0.4143
50 4IWD 1JC 4.709e-06 0.4139
51 4U0I 0LI 0.0001532 0.41345
52 3TKI S25 5.314e-08 0.41289
53 3EQR T74 2.8e-07 0.41213
54 4QTB 38Z 1.552e-06 0.411
55 3VBQ 0F5 2.91e-05 0.41008
56 3AT4 CCK 1.525e-05 0.41008
57 2PVN P63 3.691e-06 0.40728
58 2XVD AS6 1.836e-06 0.40665
59 4IZY 1J2 5.696e-07 0.40102
60 4MQ1 2C3 5.257e-07 0.39787
61 2X2M X2M 2.702e-07 0.39776
62 4OTH DRN 5.308e-08 0.39756
63 4MKC 4MK 8.972e-08 0.39667
64 3BI6 396 2.244e-07 0.39619
65 3E7O 35F 2.949e-06 0.39558
66 4KS7 X4Z 2.809e-07 0.39395
67 4ASE AV9 1.277e-06 0.39347
68 3VRY B43 5.855e-06 0.39333
69 2EVA ADN 9.414e-06 0.39284
70 3SXS PP2 5.517e-07 0.3927
71 1VJY 460 6.301e-06 0.39266
72 3V8S 0HD 3.943e-09 0.39223
73 4OTI MI1 1.737e-07 0.39181
74 4CMT GWH 8.709e-08 0.3918
75 4CTB KVC 3.955e-08 0.39
76 3LXN MI1 2.878e-07 0.38982
77 4FL3 ANP 1.362e-06 0.38959
78 3ORK AGS 4.706e-06 0.38938
79 4BHN BH9 2.426e-06 0.38923
80 4E6D 0NU 3.045e-07 0.38897
81 3FHI ANP 1.786e-05 0.38875
82 4C2W ANP 3.097e-10 0.38732
83 4E1Z 0MX 9.343e-07 0.38703
84 1XJD STU 3.009e-07 0.38692
85 3PP0 03Q 3.362e-06 0.38683
86 3U6H 03X 5.649e-05 0.38681
87 4I5C C5I 4.068e-07 0.38667
88 1OPK P16 5.014e-07 0.38528
89 3IGO ANP 2.944e-06 0.38498
90 3EFK MT4 7.837e-06 0.38455
91 3F7Z 34O 2.858e-07 0.38444
92 4QTC 38Z 1.146e-05 0.38382
93 4CD0 AWJ 3.718e-07 0.38379
94 4MK0 29X 4.612e-06 0.38369
95 4E4N 0NL 4.561e-07 0.38279
96 4EUU BX7 5.879e-06 0.38252
97 4H1M 0YJ 7.545e-05 0.38245
98 2YAB AMP 4.889e-07 0.38192
99 1V0O INR 2.245e-06 0.38107
100 4IVD 15T 7.051e-07 0.38061
101 3A7H ATP 1.747e-07 0.38036
102 3IDB ANP 8.881e-06 0.3803
103 2J90 IZA 7.081e-07 0.37856
104 4FG8 ATP 2.455e-06 0.37845
105 1U5R ATP 2.038e-07 0.37807
106 4E6Q 0NV 5.76e-07 0.37754
107 2WU6 DKI 2.806e-06 0.37709
108 3C0I 3AM 2.583e-07 0.37704
109 4FOB 0US 6.841e-07 0.37678
110 4JDI ARG 0.0003359 0.37634
111 3EYG MI1 8.286e-07 0.37575
112 3PLS ANP 4.11e-07 0.37546
113 2NRY STU 8.791e-07 0.37413
114 2B9F ADP 5.565e-06 0.37401
115 4C4F 7CE 8.31e-07 0.37373
116 3HMO STU 4.641e-07 0.37319
117 2QCS ANP 3.733e-05 0.37252
118 3A8W ATP 1.126e-06 0.37228
119 2I0D MUT 0.01917 0.37172
120 3BQC EMO 1.092e-05 0.37095
121 2B9I ADP 5.806e-06 0.36912
122 2H8H H8H 1.585e-06 0.36901
123 4KNB 1RU 1.556e-06 0.3681
124 4I6H 1C8 1.911e-06 0.36808
125 1Y57 MPZ 4.302e-06 0.36786
126 4BCM T7Z 5.986e-08 0.36777
127 4DCE 0JF 3.822e-06 0.36725
128 4O1P ANP 2.485e-06 0.36672
129 3TTI KBI 9.774e-06 0.36611
130 1PHK ATP 1.228e-05 0.36567
131 3GNI ATP 4.23e-06 0.36547
132 2Y6O 1N1 8.057e-06 0.36529
133 4UXQ 0LI 0.000138 0.36506
134 1BYG STU 7.548e-07 0.36488
135 2RFN AM7 1.53e-05 0.36482
136 4CCU AWF 2.45e-07 0.36429
137 2RIO ADP 2.525e-06 0.36427
138 4AOI 4K0 5.04e-06 0.36377
139 4CLI 5P8 2.217e-07 0.36366
140 1UNH IXM 2.232e-06 0.36321
141 4BBF O19 7.465e-07 0.36282
142 3EYH IZA 4.491e-06 0.36239
143 2PVF ACP 5.48e-06 0.36234
144 1Q8Y ADP 2.901e-05 0.36232
145 4M69 ANP 2.111e-05 0.36149
146 1Q8Y ADE 1.764e-06 0.36088
147 4E5W 0NT 2.692e-06 0.36048
148 4U44 3D9 6.232e-06 0.36006
149 2V58 LZJ 0.007177 0.35951
150 4NST ADP 6.581e-06 0.35943
151 2QU6 857 1.72e-05 0.35919
152 4CFU 2WC 1.46e-06 0.35917
153 4IVC 1J6 3.676e-06 0.3587
154 4BTK DTQ 1.425e-05 0.35828
155 2B9J ADP 1.453e-05 0.35781
156 2OIC STU 1.314e-06 0.35765
157 4IVB 1J5 1.826e-06 0.35751
158 4ANW O92 0.0007405 0.35744
159 2B9H ADP 1.453e-05 0.35696
160 4QPM ADP 1.707e-05 0.35677
161 3O0G 3O0 1.507e-06 0.3565
162 3FHR P4O 1.634e-05 0.35619
163 2P2H 994 5.804e-07 0.35582
164 2ZV2 609 1.143e-06 0.35573
165 1U59 STU 7.578e-07 0.35542
166 1R27 MGD 0.04012 0.3553
167 4CTC J99 1.327e-06 0.35525
168 4OAV ACP 1.468e-05 0.35516
169 4K1B 1OC 1.063e-06 0.35467
170 2HK5 1BM 6.474e-06 0.35466
171 4CLJ 5P8 9.298e-07 0.35461
172 3FI3 JK2 0.0003876 0.3546
173 2WQN ADP 3.396e-07 0.35455
174 4CCB OFG 3.001e-07 0.3545
175 2OO8 RAJ 0.000123 0.3543
176 2V7O DRN 2.883e-07 0.35414
177 4CMO YPW 2.461e-07 0.35361
178 3ZOS 0LI 0.001997 0.35358
179 4EWH T77 1.251e-05 0.35353
180 3ZRM ZRM 4.465e-06 0.35346
181 2XK9 XK9 0.0299 0.353
182 3GC8 B45 2.299e-05 0.35292
183 4F99 ADP 1.577e-05 0.35279
184 3GGF GVD 8.005e-07 0.35189
185 4LFI GNP 5.068e-05 0.35189
186 3SRV S19 5.495e-06 0.35163
187 2P2I 608 4.99e-05 0.35101
188 3SLS ANP 3.418e-05 0.35092
189 4JQE ANP 4.346e-06 0.35042
190 4BCN T9N 1.17e-06 0.35036
191 3SG8 TOY 0.001947 0.34942
192 4IDT T28 2.344e-05 0.34932
193 4OAC ADP 5.61e-05 0.34907
194 3ZBF VGH 5.113e-06 0.34882
195 4E4L 0NH 1.867e-06 0.34867
196 4CQE CQE 3.027e-05 0.34851
197 4OH4 ANP 3.521e-05 0.34828
198 4OUC 5ID 8.65e-06 0.34806
199 2EVL GAL 0.01916 0.34739
200 2VAG V25 2.171e-05 0.34668
201 3M2W L8I 2.102e-05 0.3466
202 3RGF BAX 0.0001447 0.34648
203 4GW8 3RA 9.185e-07 0.34639
204 1XR1 ANP 3.228e-06 0.34634
205 4I94 ANP 3.282e-05 0.34614
206 2R5T ANP 1.825e-05 0.34536
207 4JR7 GNP 1.818e-05 0.34504
208 4IJP 1EH 0.0001838 0.34503
209 3LKM AMP 0.0001595 0.34492
210 2CSN CKI 0.03561 0.34481
211 4H3Q ANP 0.0002001 0.3447
212 4OA2 ADP 3.51e-05 0.34463
213 4N70 2HX 6.749e-06 0.34451
214 4FOC 0UU 7.634e-06 0.3445
215 4BFM ANP 2.135e-05 0.34434
216 3BE2 RAJ 0.0002003 0.3443
217 4PMT 31Y 3.44e-05 0.34406
218 4N6Z 2HW 1.03e-06 0.34359
219 4LRJ ANP 9.189e-06 0.34356
220 2ZM3 575 7.534e-07 0.34329
221 4F9A ADP 2.813e-05 0.34317
222 3DLS ADP 7.9e-05 0.34314
223 4X2K 3WO 1.095e-05 0.34295
224 4X2J 3WN 1.095e-05 0.34295
225 1MQB ANP 1.282e-06 0.34274
226 4FVQ ATP 4.829e-05 0.34265
227 4JX7 1N6 2.357e-06 0.34219
228 3DAK ANP 1.443e-06 0.34194
229 2NRU T12 3.961e-05 0.3414
230 4LOO SB4 5.11e-05 0.34136
231 4C58 824 0.00497 0.3411
232 3PE2 E1B 1.227e-05 0.34087
233 4CMU IV7 7.006e-07 0.34049
234 4FK6 0UJ 1.209e-05 0.34019
235 3GC0 AMP 1.607e-06 0.34
236 4DP3 MMV 0.03268 0.33992
237 2H26 6UL 0.04475 0.33939
238 3ALN ANP 5.595e-05 0.33908
239 4IX4 ADP 0.000333 0.33906
240 3GQI ACP 4.423e-05 0.33866
241 4CKR DI1 0.0004775 0.33848
242 1ZP9 ATP 4.203e-05 0.33828
243 3CV6 HXS 0.02148 0.33791
244 2P4Y C03 0.03763 0.33755
245 4M7V RAR 0.03086 0.33747
246 3R0T FU9 1.827e-05 0.3367
247 1ZY5 ANP 1.435e-06 0.33661
248 3QUP LUN 0.0001527 0.33635
249 3PTG 932 1.308e-07 0.33618
250 1AOE GW3 0.03049 0.33591
251 3RG9 NDP 0.02385 0.33588
252 4K77 1Q4 3.962e-06 0.33572
253 1V97 MTE 0.04045 0.3357
254 2J7T 274 0.04032 0.33549
255 1PK8 ATP 0.001879 0.33547
256 3C1X CKK 0.0003787 0.33495
257 4PMM 31V 0.0001105 0.33487
258 3TZM 085 0.0001155 0.3347
259 3PE1 3NG 1.162e-05 0.33448
260 3UIM ANP 4.114e-05 0.33418
261 4EI4 0Q2 2.382e-06 0.3341
262 1IA9 ANP 0.0004051 0.33395
263 4CYI ATP 0.0001719 0.33343
264 4GRB 0XG 2.291e-06 0.33262
265 4F0F ACP 9.896e-06 0.3322
266 2VN9 GVD 2.38e-07 0.33216
267 3PPM JG1 0.01679 0.33135
268 3RE4 TO1 0.0001637 0.33128
269 3H9R TAK 3.23e-05 0.33124
270 2WXG ZZN 0.003489 0.33097
271 1K3A ACP 3.666e-06 0.33073
272 3TDV GDP 0.0006011 0.3307
273 3V66 D3A 0.02906 0.33061
274 1XSE NDP 0.03729 0.33045
275 3BRB ADP 0.0001099 0.33038
276 4TW9 386 9.928e-05 0.33028
277 3KN5 ANP 1.033e-05 0.32955
278 4BKJ STI 0.0008104 0.32933
279 1FRB ZST 0.04424 0.32915
280 1TQP ATP 0.001625 0.32879
281 4EIL NDP 0.03589 0.3287
282 4H3P ANP 7.185e-05 0.32865
283 2OID ANP 0.0001264 0.32857
284 1I7L ATP 0.0005219 0.32772
285 4KBA 1QM 0.0001672 0.32757
286 2A19 ANP 3.558e-06 0.32742
287 4MWH ATP 0.001064 0.3273
288 2VVL FAD 0.03054 0.32685
289 3UZP 0CK 5.762e-05 0.32646
290 3Q60 ATP 0.0002032 0.32612
291 2WEI VGG 3.716e-05 0.32612
292 3TXO 07U 3.963e-05 0.3261
293 3OKI OKI 0.02542 0.32603
294 2ZCQ B65 0.03903 0.3259
295 1VA6 P2S 0.02665 0.32586
296 3UYT 0CK 0.0001388 0.32486
297 4PMP 31W 0.0001292 0.3247
298 4TWC 37J 0.0002856 0.32439
299 4DEH 0JK 4.079e-05 0.32405
300 4BBE 3O4 1.865e-06 0.32388
301 4EHZ JAK 1.869e-05 0.3235
302 2X32 OTP 0.04848 0.32296
303 3UDZ ADP 0.0004581 0.32293
304 4NFN 2KC 4.541e-05 0.32286
305 2VZ6 FEF 3.129e-05 0.32279
306 1SIV PSI 0.04037 0.32277
307 3PG7 PTY 0.01837 0.32242
308 1M9H NAD 0.0134 0.32161
309 1WBP ADP 3.504e-06 0.32145
310 1GVE NAP 0.04396 0.32135
311 1ZTH ADP 0.0001403 0.32134
312 4F1M ACP 2.729e-05 0.32099
313 4G16 0VM 0.000239 0.32091
314 2Q4W FAD 0.04062 0.32087
315 3RUX BS5 0.01663 0.32034
316 4F9C 0SX 7.071e-05 0.3201
317 3CXW 7CP 3.46e-05 0.31968
318 4MBI 26K 8.394e-06 0.3196
319 4CNH 3U9 5.47e-07 0.31835
320 3C0G 3AM 6.308e-07 0.31832
321 4ORK GDP 0.001363 0.31789
322 3LVW GSH 0.03853 0.31733
323 4WLB 3QQ 0.03782 0.3168
324 2PUL ACP 0.0009898 0.31658
325 4JVF 17X 0.01784 0.3165
326 3FAL LO2 0.04878 0.31575
327 4EYM 0RX 0.001471 0.31551
328 3CY2 MB9 6.645e-06 0.31551
329 2PYW ADP 0.0005577 0.31531
330 3H7U NAP 0.03245 0.31513
331 1VP5 NAP 0.03042 0.31465
332 3W0O ADP 0.03255 0.31449
333 4KBC 1QJ 3.869e-06 0.31446
334 3PDT ADP 0.001391 0.3142
335 1Z2P ACP 0.04354 0.31378
336 3E2M E2M 0.02624 0.31358
337 4DC2 ADE 7.023e-06 0.31353
338 2VPQ ANP 0.005837 0.31347
339 4AZW ATP 0.00501 0.31333
340 4OCV ANP 0.008441 0.31308
341 1CM8 ANP 0.0007744 0.31306
342 3NUB UD0 0.04994 0.31273
343 3H7R NAP 0.03728 0.31263
344 3AQV TAK 8.744e-05 0.3124
345 3HAV ATP 0.005266 0.31233
346 1EHI ADP 0.007522 0.3121
347 3BU5 ATP 0.0001098 0.31204
348 2O2U 738 3.102e-05 0.312
349 2ODE ALF 0.02701 0.31197
350 4BCQ TJF 6.925e-05 0.31187
351 2YW2 ATP 0.005506 0.31186
352 4HNF 16W 3.445e-05 0.31137
353 2VQD AP2 0.007781 0.31123
354 1LLF F23 0.03947 0.31122
355 3U7S 017 0.03358 0.31121
356 2J51 DKI 0.04361 0.31032
357 4ELG 52I 0.03805 0.30996
358 4AU8 Z3R 0.0003547 0.30985
359 4PU5 ANP 0.01273 0.30968
360 4F9B 0SY 0.0001417 0.30954
361 4G17 0VN 0.002063 0.30897
362 4IE6 UN9 0.01389 0.30845
363 2VC7 HT5 0.01394 0.30823
364 4X0M 3WA 9.095e-06 0.30813
365 3WCA FPS 0.03685 0.30786
366 3VPC ADP 0.00942 0.3078
367 4KWP EXX 0.0001473 0.30703
368 4B0T ADP 0.0275 0.30656
369 3AKK ADP 0.002995 0.30651
370 3VOT ADP 0.004643 0.30633
371 1KGI T4A 0.01988 0.30614
372 3C0H AMP 3.978e-06 0.30526
373 1OGX EQU 0.004895 0.30511
374 4GYI ADP 0.002677 0.30498
375 4BVN P32 0.02945 0.30419
376 2WEL K88 6.665e-07 0.30412
377 2V0U FMN 0.0148 0.30405
378 2GQS C2R 0.002966 0.30402
379 4USI ATP 0.04809 0.30377
380 2DYP ARG 0.04903 0.30352
381 1TPY SAH 0.03517 0.3035
382 2Z6C FMN 0.015 0.30341
383 3PFF ADP 0.003133 0.30333
384 3WVR AMP 0.003369 0.30309
385 3HZT J60 0.0001812 0.30301
386 4O4F ATP 0.03803 0.30292
387 4EES FMN 0.01772 0.30292
388 2WKQ FMN 0.02973 0.30247
389 3L0E G58 0.02728 0.30243
390 4Q5H ANP 0.007583 0.30236
391 3DNT ATP 0.0318 0.3023
392 2FK8 SAM 0.02421 0.30197
393 3PLZ 470 0.04346 0.3019
394 3OWL 19E 0.0001361 0.30129
395 2HSA FMN 0.04387 0.30086
396 2ICY UPG 0.02842 0.30084
397 3T50 FMN 0.01733 0.30023
398 1TT8 PHB 0.02459 0.29959
399 2GC0 PAN 0.01082 0.29939
400 2QV6 GTP 0.0444 0.29938
401 2RDE C2E 0.007027 0.29891
402 2PZI AXX 0.00142 0.29869
403 1ZB6 GST 0.03596 0.29857
404 3JPV 1DR 2.591e-05 0.29809
405 4AUA 4AU 2.774e-05 0.29748
406 4RC7 PL3 0.005817 0.29738
407 3JRX S1A 0.00427 0.29725
408 2GTE VA 0.02798 0.29713
409 2Y0E UGA 0.03883 0.29698
410 3KMW ATP 0.01007 0.29691
411 2Z6D FMN 0.02378 0.29679
412 2ADA HPR 0.03409 0.29671
413 2FXV 5GP 0.0404 0.29644
414 3I0O ADP 0.008927 0.29603
415 4GBD MCF 0.02185 0.29545
416 3EFS BTN 0.03659 0.29539
417 3KYF 5GP 0.0171 0.29523
418 1N5S ADL 0.03101 0.29513
419 4F1O ACP 0.0002973 0.29465
420 4DXD 9PC 0.02892 0.29441
421 4GCZ FMN 0.03069 0.29433
422 4O2B ACP 0.04023 0.29428
423 2FR3 REA 0.04816 0.29424
424 1DZK PRZ 0.0167 0.29383
425 1RDT 570 0.04811 0.29372
426 4WT2 3UD 0.01496 0.29365
427 3OFM 4B0 0.0001096 0.29361
428 2PR5 FMN 0.03708 0.29356
429 4RC8 STE 0.02036 0.29336
430 4IPH 1FJ 0.04969 0.29317
431 3LLI FAD 0.04484 0.29311
432 1LO0 BC1 0.03587 0.2928
433 2CFM AMP 0.005156 0.29264
434 4BNU 9KQ 0.0467 0.29251
435 4AZ3 S35 0.02579 0.29208
436 3SLS 77D 0.003457 0.29171
437 3EQ9 X97 0.03877 0.29169
438 1SW0 PGA 0.03663 0.29108
439 3B1Q NOS 0.03096 0.29105
440 3GFZ FMN 0.02167 0.29096
441 1NY5 ADP 0.007317 0.2909
442 1Q0R AKT 0.03189 0.29084
443 2H04 4UN 0.03961 0.29045
444 3OWK 18E 0.0002888 0.28876
445 3NKS ACJ 0.008641 0.28847
446 3IUY AMP 0.01078 0.28811
447 1SN0 T44 0.0109 0.2878
448 2OXY K17 0.000128 0.2878
449 2GQS ADP 0.02493 0.28734
450 2BKK ADP 0.04633 0.28705
451 1UA4 AMP 0.01656 0.28679
452 2YPI PGA 0.03112 0.28676
453 3GHB LYS 0.03588 0.2866
454 2QLU ADE 8.282e-05 0.28651
455 4JE7 BB2 0.03194 0.2859
456 2E0N SAH 0.03934 0.2856
457 1G27 BB1 0.03961 0.28518
458 2CM4 RCL 0.0279 0.2851
459 2O5L MNR 0.03068 0.28498
460 3GHB LYS 0.04148 0.28469
461 3GNP SOG 0.03609 0.28462
462 1X0P FAD 0.01285 0.28416
463 2GQR ADP 0.03621 0.28398
464 1YRX FMN 0.03995 0.28353
465 1J3R 6PG 0.01719 0.28313
466 4LBK GAL 0.04839 0.2831
467 2FF4 SER 0.01223 0.28288
468 4AZT LY2 0.02682 0.28279
469 4F1T H52 0.002564 0.28231
470 2CHG ANP 0.0425 0.28213
471 1V59 NAD 0.04789 0.28092
472 3G5K BB2 0.03357 0.28014
473 4CYD CMP 0.03949 0.27972
474 4FF8 14S 0.001339 0.2794
475 4TSZ ACE 0.0407 0.27887
476 2IVD ACJ 0.03579 0.2782
477 4UWH JXM 0.01607 0.27725
478 3TII ANP 0.0155 0.27717
479 2BS3 CIT 0.04488 0.27709
480 2QK4 ATP 0.01506 0.27695
481 3MB6 01I 0.0003114 0.27693
482 3EW2 BTN 0.04346 0.27678
483 2FN1 SAL 0.03915 0.27674
484 2PEH LYS 0.01194 0.27653
485 4FE2 AIR 0.03675 0.27639
486 3SE5 ANP 0.03018 0.27623
487 4G31 0WH 0.000272 0.27541
488 4DYO SD4 0.04208 0.27525
489 2BJ4 OHT 0.03418 0.27358
490 3N9R TD3 0.02415 0.27347
491 3ZJX BOG 0.001126 0.27314
492 4IEE AGS 0.01195 0.27312
493 3WAR NIO 0.0001119 0.27286
494 2XZ9 PYR 0.02623 0.27226
495 3CHT 4NB 0.01473 0.2719
496 2XG5 EC5 0.00104 0.27179
497 1XN0 ROL 0.03256 0.27167
498 3DGY 2GP 0.03078 0.27152
499 1JPA ANP 0.0001102 0.27122
500 2IF8 ADP 0.006949 0.27076
501 2QHV OC9 0.01543 0.27051
502 4DSU BZI 0.01295 0.27028
503 1CBK ROI 0.0383 0.26971
504 2XQ0 BES 0.01592 0.26903
505 4RLL E91 0.003447 0.26886
506 4BMB LAT 0.006347 0.2687
507 2XG5 EC2 0.0001377 0.26858
508 3R42 GLN 0.03677 0.26854
509 3SAO NKN 0.04939 0.26849
510 4MA7 P2Z 0.01003 0.26848
511 2QHS OCA 0.04565 0.26788
512 3TL1 JRO 0.02287 0.26698
513 4DFU QUE 0.03024 0.26663
514 4JPS 1LT 0.0497 0.26653
515 4DOL PLM 0.04198 0.26636
516 4KEC COA 0.04827 0.26613
517 4MA6 28E 0.009268 0.26591
518 2WZ5 MET 0.0001495 0.26504
519 4SGA ACE 0.02576 0.26477
520 1A4K FRA 0.009724 0.26471
521 4AIF SER 0.02767 0.26461
522 3DBX PLM 0.04654 0.26413
523 3I27 SID 0.04492 0.26409
524 1NQ7 HIS 0.008728 0.26409
525 3SQP 3J8 0.007597 0.26383
526 2PIE GLU 0.009842 0.2633
527 1G51 AMP 0.009146 0.26294
528 3UNN MET 0.03319 0.26276
529 2YRX AMP 0.04687 0.26263
530 2F67 12B 0.01224 0.26175
531 2V7Q ADP 0.04892 0.26173
532 1DDV THR 0.007058 0.26087
533 1ALW ISA 0.04154 0.26032
534 2UW1 GVM 0.03377 0.25979
535 4RHP PEF 0.04219 0.25975
536 1XPJ TLA 0.00981 0.25851
537 3QBC B55 0.02625 0.25827
538 1WKM MET 0.04949 0.25806
539 2GJP MAL 0.008855 0.25801
540 3P1D MB3 0.03327 0.2574
541 1ZOY UQ1 0.042 0.25702
542 2ZPG TB0 0.03596 0.25632
543 1OFL NGK 0.01852 0.25567
544 1TZD ADP 0.04984 0.25561
545 1P7T PYR 0.03534 0.25538
546 1VPD TLA 0.01217 0.25512
547 1HPG BOC 0.03664 0.25454
548 2Z9I GLY 0.01198 0.25375
549 4URG C2E 0.03786 0.25335
550 3CV2 OXL 0.01911 0.25318
551 4QAG F95 0.04111 0.25139
552 2G30 ALA 0.006155 0.25082
553 3O01 DXC 0.002119 0.25
554 1I0B PEL 0.04732 0.24991
555 1XXR MAN 0.02781 0.24989
556 1D8C GLV 0.0381 0.24985
557 3AJ4 SEP 0.01915 0.2493
558 1OD3 BGC 0.002405 0.24923
559 4I9B 1KA 0.0273 0.2491
560 3SJK LYS 0.04275 0.24827
561 2B6N ALA 0.02414 0.24804
562 4MRP GSH 0.0356 0.24789
563 3F5A SIA 0.002415 0.24642
564 3ETG GWD 0.03853 0.24556
565 1UGY GLA 0.04114 0.24336
566 3FW3 GLC 0.04642 0.24187
567 3SXU ASP 0.03326 0.24122
Feedback