Receptor
PDB id Resolution Class Description Source Keywords
3i65 2 Å EC: 1.3.5.2 PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH TRIAZOLOPYRIMIDINE-BASED INHIBITOR DSM1 PLASMODIUM FALCIPARUM 3D7 PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE TRIAZOLOPYRIMIDINEINHIBITOR DSM1 FAD FLAVOPROTEIN MEMBRANE MITOCHONDRION MITOCHONDRION INNER MEMBRANE OXIDOREDUCTASE PYRIMIDINE BIOSYNTHESIS TRANSIT PEPTIDE
Ref.: STRUCTURAL PLASTICITY OF MALARIA DIHYDROOROTATE DEHYDROGENASE ALLOWS SELECTIVE BINDING OF DIVERSE CHEMICAL SCAFFOLDS. J.BIOL.CHEM. V. 284 26999 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FMN A:1002;
Valid;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
JZ8 A:1001;
Valid;
none;
ic50 = 0.047 uM
277.324 C16 H15 N5 Cc1cc...
LDA A:1004;
Invalid;
none;
submit data
229.402 C14 H31 N O CCCCC...
ORO A:1003;
Valid;
none;
submit data
156.096 C5 H4 N2 O4 C1=C(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4ORM 2.07 Å EC: 1.3.5.2 CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM338 (N-[3,5-DIFLUORO-( TRIFLUOROMETHYL)PHENYL]-5-METHYL-2-(TRIFLUOROMETHYL)[1,2, 4] TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE) PLASMODIUM FALCIPARUM ALPHA/BETA BARREL OXIDOREDUCTASE FMN MITOCHONDRIAL MEMBRAOXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
Ref.: FLUORINE MODULATES SPECIES SELECTIVITY IN THE TRIAZOLOPYRIMIDINE CLASS OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE INHIBITORS. J.MED.CHEM. V. 57 5381 2014
Members (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3I65 ic50 = 0.047 uM JZ8 C16 H15 N5 Cc1cc([n+]....
2 4CQ8 ic50 = 0.08 uM JBW C17 H14 N4 O S Cc1nc2c(cc....
3 3I68 ic50 = 0.056 uM J4Z C20 H15 N5 Cc1cc(n2c(....
4 4ORM ic50 = 0.0018 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
5 3O8A ic50 = 0.022 uM O8A C17 H14 F3 N3 O2 S Cc1nc2cc(c....
6 3I6R ic50 = 0.28 uM J5Z C13 H10 F3 N5 Cc1cc(n2c(....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1TV5 Ki ~ 1000 nM A26 C12 H9 F3 N2 O2 CC(=C(C#N)....
2 3I65 ic50 = 0.047 uM JZ8 C16 H15 N5 Cc1cc([n+]....
3 4CQ8 ic50 = 0.08 uM JBW C17 H14 N4 O S Cc1nc2c(cc....
4 3I68 ic50 = 0.056 uM J4Z C20 H15 N5 Cc1cc(n2c(....
5 4ORM ic50 = 0.0018 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
6 3O8A ic50 = 0.022 uM O8A C17 H14 F3 N3 O2 S Cc1nc2cc(c....
7 3I6R ic50 = 0.28 uM J5Z C13 H10 F3 N5 Cc1cc(n2c(....
50% Homology Family (35)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1TV5 Ki ~ 1000 nM A26 C12 H9 F3 N2 O2 CC(=C(C#N)....
2 2FQI ic50 = 7 nM ILH C20 H10 F7 N O4 c1cc(cc(c1....
3 3KVL ic50 = 5.5 uM 7Z5 C17 H19 N3 O3 CCC(=O)Nc1....
4 3F1Q ic50 = 0.117 uM BCE C17 H14 N2 O2 CC(=C(C#N)....
5 3ZWS ic50 = 0.051 uM AVQ C13 H10 Cl2 N4 O S Cc1cc(n2c(....
6 2FPT ic50 = 33 nM ILB C20 H14 F5 N O4 c1cc(cc(c1....
7 3G0X ic50 = 0.053 uM MD7 C19 H16 N2 O2 c1ccc(cc1)....
8 2PRL ic50 = 81 nM R2C C20 H17 N O4 COc1ccc(c(....
9 2FPY ic50 = 2 nM ILF C19 H10 F5 N O4 S c1cc(cc(c1....
10 3FJ6 ic50 = 0.022 uM CIH C17 H12 Cl2 N2 O2 CC(=C(C#N)....
11 3G0U ic50 = 0.2 uM MDY C18 H15 Cl N2 O3 CC(=C(C#N)....
12 4IGH ic50 = 1 nM 1EA C26 H22 F N O3 Cc1cc(c(cc....
13 4OQV ic50 = 1.6 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
14 2B0M - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
15 3FJL ic50 = 0.13 uM CJH C19 H18 N2 O3 CCOc1cccc(....
16 2PRH ic50 = 15 nM 238 C23 H15 Cl F N O2 Cc1c(c2cc(....
17 2FPV ic50 = 44 nM ILC C19 H14 F N O4 S COc1cccc(c....
18 3U2O ic50 = 110 nM 03U C20 H17 F N2 O4 CCC(=C(C#N....
19 3ZWT ic50 = 0.013 uM KFZ C14 H12 Cl2 N4 O S CCc1cc(n2c....
20 3KVK ic50 = 0.7 uM 6X1 C14 H10 Cl2 N2 O3 c1ccc(c(c1....
21 1D3G - BRE C23 H16 F N O2 Cc1c(c2cc(....
22 3KVM ic50 = 0.5 uM 951 C18 H13 Cl N2 O3 c1ccc(c(c1....
23 2BXV ic50 = 280 nM 3FT C20 H15 F4 N O4 c1cc(cc(c1....
24 3KVJ ic50 = 0.1 uM 1X5 C18 H19 N3 O3 CN(Cc1cccn....
25 2WV8 ic50 = 0.21 uM VGN C21 H17 N O3 CC(=O)Nc1c....
26 1D3H - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
27 3I65 ic50 = 0.047 uM JZ8 C16 H15 N5 Cc1cc([n+]....
28 4CQ8 ic50 = 0.08 uM JBW C17 H14 N4 O S Cc1nc2c(cc....
29 3I68 ic50 = 0.056 uM J4Z C20 H15 N5 Cc1cc(n2c(....
30 4ORM ic50 = 0.0018 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
31 3O8A ic50 = 0.022 uM O8A C17 H14 F3 N3 O2 S Cc1nc2cc(c....
32 3I6R ic50 = 0.28 uM J5Z C13 H10 F3 N5 Cc1cc(n2c(....
33 1UUO ic50 = 6 nM BRF C23 H15 F2 N O2 Cc1c(c2cc(....
34 4ORI ic50 = 0.088 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
35 1UUM ic50 = 698 nM AFI C22 H19 Cl O3 c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FMN; Similar ligands found: 15
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAD 0.543307 0.876543
5 FAS 0.543307 0.876543
6 FAE 0.539062 0.865854
7 DAL FAD PER 0.5 0.833333
8 LFN 0.475 0.643836
9 C3F 0.473684 0.74359
10 CF4 0.463918 0.734177
11 FAY 0.446043 0.864198
12 FNR 0.444444 0.909091
13 RFL 0.442857 0.845238
14 1VY 0.406593 0.769231
15 DLZ 0.404494 0.782051
Ligand no: 2; Ligand: JZ8; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 JZ8 1 1
Ligand no: 3; Ligand: ORO; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 ORO 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4ORM; Ligand: ORO; Similar sites found: 315
This union binding pocket(no: 1) in the query (biounit: 4orm.bio1) has 60 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1F76 ORO 0.0000000003087 0.93028
2 1F76 FMN 0.00000000000003497 0.92289
3 1F76 FMN 0.00000000000004052 0.92009
4 1F76 FMN 0.00000000000004374 0.91862
5 1F76 FMN 0.00000000000004619 0.91757
6 3OIX FMN 0.000000000009972 0.83326
7 1OVD ORO 0.0000000000001503 0.80769
8 1OVD FMN 0.0000000000001503 0.80769
9 3MJY IJZ 0.000000000000942 0.80734
10 3MJY FMN 0.000000000000942 0.80734
11 3OIX FMN 0.00000000004266 0.80448
12 3OIX FMN 0.00000000004266 0.80448
13 3C3N FMN 0.0000000000004962 0.79531
14 1EP2 FMN 0.0000000001294 0.74983
15 1EP2 ORO 0.0000000000194 0.74061
16 1GTE FMN 0.0000000001644 0.70435
17 1GTE IUR 0.0000000001644 0.70435
18 1GTE FMN 0.0000000002646 0.69023
19 1GTE IUR 0.0000000002646 0.69023
20 4IA6 EIC 0.00003018 0.61636
21 3B0P FMN 0.00001923 0.57974
22 3B0P FMN 0.00002035 0.57849
23 2Q3R FMN 0.00001387 0.56893
24 1Z41 FMN 0.00009629 0.54413
25 1Z41 FMN 0.00009629 0.54413
26 1Z44 FMN 0.000126 0.54384
27 1Z44 FMN 0.000126 0.54384
28 1Z48 FMN 0.00009923 0.54347
29 1Z42 FMN 0.000172 0.54263
30 1Z42 FMN 0.000172 0.54263
31 3QH2 3NM 0.0004224 0.54023
32 3QH2 3NM 0.0005067 0.53574
33 4JEJ 1GP 0.0002321 0.53573
34 4QNW FMN 0.00006267 0.53255
35 3TDC 0EU 0.0005864 0.52873
36 4NAE 1GP 0.001118 0.52128
37 2Q3O FMN 0.000165 0.50836
38 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.003421 0.5074
39 3EXS 5RP 0.001032 0.50661
40 4JIQ FMN 0.000167 0.50395
41 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.00228 0.50179
42 2Q3O FMN 0.0001707 0.49952
43 1NF8 BOG 0.003191 0.4992
44 2HSA FMN 0.00008036 0.49871
45 3W9Z FMN 0.0005143 0.49783
46 4M5P FMN 0.0003696 0.49618
47 3B9Z CO2 0.001731 0.48928
48 1AL8 FMN 0.0003695 0.48823
49 1VYP TNF 0.0003083 0.48801
50 4JIQ 1L5 0.0002609 0.48755
51 1ICP FMN 0.000151 0.48718
52 1KBI PYR 0.000222 0.48702
53 1KBI FMN 0.000222 0.48702
54 3BW2 FMN 0.0001264 0.48701
55 1ICP FMN 0.000172 0.4848
56 3EXS 5RP 0.002269 0.48318
57 2NLI LAC 0.0004828 0.48293
58 2NLI FMN 0.0004828 0.48293
59 2NLI FMN 0.0004828 0.48293
60 2VWA PTY 0.005187 0.48292
61 4EWN 0VR 0.001569 0.48244
62 2Z6I FMN 0.000606 0.48215
63 1VHN FMN 0.002395 0.48193
64 3ATY FMN 0.0005473 0.48045
65 1VYP FMN 0.0003809 0.4803
66 2RDT FMN 0.0004169 0.47857
67 1KBJ FMN 0.0004221 0.47834
68 2F6U CIT 0.00525 0.47801
69 2GJN FMN 0.000466 0.47644
70 2GJN FMN 0.000466 0.47644
71 2WOR 2AN 0.006952 0.47621
72 4UTU LRY 0.002711 0.47458
73 3ATY FMN 0.0006734 0.4728
74 1OYB FMN 0.0008168 0.47252
75 3SP6 IL2 0.001967 0.46929
76 1TRD PGH 0.004156 0.46922
77 1TRD PGH 0.004156 0.46922
78 2O1V ADP 0.005401 0.46758
79 3B6C SDN 0.008705 0.46549
80 2GJN NIS 0.0005867 0.46549
81 2GJN NIS 0.0005867 0.46549
82 1GVF PGH 0.009119 0.46434
83 1AL8 DHP 0.0005703 0.4599
84 2NLI FMN 0.001003 0.45859
85 4V3I ASP LEU THR ARG PRO 0.01435 0.4575
86 2R14 FMN 0.001118 0.45654
87 2Z6J FMN 0.0008431 0.45576
88 2RDT 2RD 0.0006265 0.45532
89 2FDW D3G 0.01094 0.45522
90 2NPA MMB 0.002757 0.45496
91 1B57 PGH 0.009392 0.45451
92 2VWA PTY 0.01741 0.45396
93 1OFD AKG 0.0005026 0.4536
94 3ET1 ET1 0.00418 0.45324
95 2ZRU FMN 0.0003272 0.45284
96 1QDS PGA 0.01011 0.45276
97 1OFD AKG 0.0005369 0.45246
98 2NLI LAC 0.001192 0.45234
99 2NLI LAC 0.001192 0.45234
100 1OYB HBA 0.00145 0.45164
101 3TAO PGH 0.01105 0.45066
102 4HBM 0Y7 0.0132 0.45066
103 4HBM 0Y7 0.0132 0.45066
104 2FLI DX5 0.004042 0.45045
105 3KO0 TFP 0.01253 0.45043
106 1VKF CIT 0.0162 0.45007
107 4M26 AKG 0.01809 0.44958
108 4WLB SER LEU LEU LYS LYS LEU LEU ASP 0.01767 0.44918
109 3KO0 TFP 0.01339 0.44864
110 1Q6O LG6 0.007416 0.44804
111 1Q6O LG6 0.007416 0.44804
112 4OAS 2SW 0.008834 0.44787
113 3KO0 TFP 0.01275 0.44769
114 4BI7 PGA 0.01515 0.44732
115 2BTM PGA 0.01525 0.44716
116 1OFD FMN 0.0005868 0.4457
117 1Q1Y BB2 0.009817 0.44548
118 1SW0 PGA 0.01166 0.44536
119 2VWA PTY 0.0252 0.44524
120 2BYC FMN 0.01001 0.44504
121 3KRU FMN 0.0009633 0.445
122 4I67 G G G RPC 0.01456 0.44412
123 1OFD FMN 0.0006451 0.44412
124 2FLI DX5 0.004715 0.44394
125 3WMX THR 0.003999 0.44351
126 1M2Z BOG 0.02188 0.44296
127 4AF0 IMP 0.004283 0.44273
128 4OKZ 3E9 0.003802 0.44204
129 4I9A NCN 0.008387 0.44176
130 2NPA MMB 0.00386 0.44174
131 2BYC FMN 0.01379 0.44147
132 3O01 DXC 0.03734 0.44115
133 4AF0 IMP 0.004652 0.44107
134 3ET1 ET1 0.009035 0.44014
135 1H5R THM 0.0174 0.43989
136 4MLM TLA 0.02561 0.43953
137 3W54 RNB 0.01286 0.43934
138 4LWU 20U 0.01312 0.4389
139 1DJN FMN 0.004585 0.43833
140 3NV6 CAM 0.008713 0.43822
141 3A2Q ACA ACA 0.009917 0.43811
142 4HBM 0Y7 0.01905 0.43774
143 3FAL REA 0.01403 0.43738
144 3FAL REA 0.01403 0.43738
145 1MT1 AG2 0.03315 0.43698
146 2YFB SIN 0.01365 0.43667
147 3AQT RCO 0.03117 0.43653
148 4Q9N 0WE 0.01494 0.43594
149 3ZGJ RMN 0.02432 0.43581
150 4G8R 96P 0.03295 0.43504
151 4Q9N 0WE 0.01557 0.435
152 3A75 GLU 0.03197 0.43482
153 3VKC FPQ 0.007578 0.43419
154 3A75 GLU 0.03319 0.43404
155 2YLD CMO 0.03227 0.43341
156 4HBM 0Y7 0.02367 0.43257
157 4HBM 0Y7 0.02367 0.43257
158 1LYX PGA 0.01742 0.43246
159 1LYX PGA 0.01742 0.43246
160 2H8Z FMN 0.004046 0.43228
161 4MLM TLA 0.0305 0.43201
162 4MLM TLA 0.0305 0.43201
163 1VKF CIT 0.03391 0.432
164 2R14 TXD 0.002367 0.43174
165 4HBM 0Y7 0.0252 0.43108
166 2WG9 OCA 0.03476 0.43101
167 3FEI CTM 0.008919 0.43083
168 3OVR 5SP 0.007969 0.43019
169 2YPI PGA 0.02627 0.43009
170 2WG9 OCA 0.03645 0.42982
171 3GLC R5P 0.02327 0.42931
172 3GLC R5P 0.02344 0.42914
173 4A3R CIT 0.02035 0.42892
174 1G27 BB1 0.01315 0.42878
175 2VVG ADP 0.0444 0.42874
176 1P4C FMN 0.002838 0.42853
177 1NQ7 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 0.03281 0.42849
178 3P9T TCL 0.02813 0.42845
179 1CX9 NHP 0.00583 0.428
180 4HBM 0Y7 0.02874 0.42794
181 2DBX GLU 0.04281 0.4274
182 2CB8 MYA 0.04317 0.42736
183 1C3X 8IG 0.03219 0.42708
184 4HBM 0Y7 0.03016 0.42679
185 4IBF 1D5 0.02253 0.42659
186 4HBM 0Y7 0.03052 0.42651
187 2H8Z 8CM 0.004802 0.42645
188 1OX5 1PR 0.004845 0.42629
189 3IT6 ORN 0.04169 0.42626
190 1MT1 AG2 0.04279 0.42578
191 3KO0 TFP 0.04062 0.42526
192 1OX5 1PR 0.005143 0.42518
193 1TPY 16A 0.02079 0.42511
194 1SQS TLA 0.04218 0.42503
195 4IBF 1D5 0.02445 0.42473
196 1DKF BMS 0.01063 0.42436
197 2IYG FMN 0.02889 0.42426
198 2D6M LBT 0.02287 0.42383
199 3G58 988 0.03437 0.42366
200 1UJP CIT 0.01928 0.4236
201 2FJK 13P 0.03453 0.42355
202 4HW3 19G 0.03458 0.42352
203 4N6W FLC 0.03019 0.42324
204 1YRX FMN 0.02293 0.42291
205 4F4S EFO 0.0484 0.42267
206 1WDD CAP 0.01529 0.42257
207 1NU4 MLA 0.04312 0.4224
208 1NU4 MLA 0.04312 0.4224
209 1K7L 544 0.00906 0.42211
210 2PRG BRL 0.02064 0.42211
211 3ZGJ RMN 0.04982 0.42194
212 1SDW IYT 0.0321 0.42179
213 1K7L 544 0.008088 0.42171
214 4IXH IMP 0.01061 0.42166
215 1XN0 ROL 0.04375 0.42142
216 2C6Q IMP 0.009467 0.42126
217 3G58 988 0.0384 0.421
218 3LBZ Z89 0.0479 0.42084
219 2C6Q IMP 0.009677 0.42083
220 2PX6 DH9 0.02531 0.4207
221 3FEA ACE PHE MET AIB PM3 6CW GLU 1AC LEU NH2 0.03944 0.42036
222 1K7L 544 0.008772 0.42015
223 2V68 CAP 0.0172 0.42009
224 2V63 CAP 0.01513 0.41994
225 3VGL ANP 0.02645 0.41972
226 3RK0 AMP 0.03538 0.41952
227 2V67 CAP 0.01565 0.41924
228 1RBL CAP 0.0139 0.41892
229 4HW3 19G 0.04191 0.4189
230 4C2G ALA ALA ALA ALA 0.0489 0.41868
231 2GOU FMN 0.003836 0.41858
232 3W54 RNB 0.02455 0.4183
233 2G50 ALA 0.04327 0.41813
234 2GTE VA 0.01274 0.41802
235 2VDH CAP 0.01666 0.41794
236 3VV1 GAL FUC 0.04266 0.41755
237 2TPS TPS 0.01005 0.41753
238 2TPS TPS 0.01011 0.41742
239 1UZH CAP 0.01723 0.41725
240 2CIX CEJ 0.04144 0.41691
241 1IR2 CAP 0.01761 0.41679
242 3B99 U51 0.0399 0.41669
243 1DE6 RNS 0.04004 0.41661
244 1K7L 544 0.01064 0.41643
245 1UZD CAP 0.01805 0.41629
246 4HW3 19G 0.0354 0.41625
247 4WCK API 0.02696 0.41625
248 3G58 988 0.04696 0.41616
249 1S17 GNR 0.02387 0.41599
250 3CR3 ADP 0.02101 0.41587
251 1IR2 CAP 0.01849 0.41579
252 1ULE GLA GAL NAG 0.03749 0.41565
253 1T0S BML 0.03323 0.41515
254 1T0S BML 0.03323 0.41515
255 4OAR 2S0 0.02197 0.41493
256 2BJ4 OHT 0.02223 0.41469
257 2JGV ADP 0.04362 0.41459
258 4J2V DIU 0.02594 0.41419
259 3RET PYR 0.03887 0.4141
260 3RET SAL 0.03887 0.4141
261 3SIX GDP 0.04456 0.41409
262 3SIX GDP 0.04456 0.41409
263 2UZ1 TPP 0.01211 0.41394
264 2QCD U5P 0.02307 0.4139
265 4RC7 PL3 0.03434 0.41386
266 3CR3 ADP 0.02401 0.41305
267 1TIQ COA 0.04069 0.41305
268 3CR3 ADP 0.02401 0.41305
269 2AKO ADP 0.03608 0.41275
270 4EKQ NPO 0.03182 0.4126
271 4EKQ NPO 0.03182 0.4126
272 1S8G DAO 0.04823 0.41223
273 1TIQ COA 0.03697 0.4122
274 4OAS 2SW 0.02922 0.41162
275 3M31 FAD 0.01799 0.41113
276 3M31 FAD 0.01799 0.41113
277 3GAY P6T 0.0265 0.41097
278 1YRX FMN 0.04485 0.4108
279 3D78 NBB 0.02082 0.41071
280 4MPN PV0 0.0169 0.4099
281 3RV5 DXC 0.04622 0.40955
282 4HBM 0Y7 0.02561 0.40904
283 3VV1 GAL FUC 0.0442 0.40899
284 4NB5 2JT 0.03372 0.40853
285 2OL1 UMP 0.0437 0.40842
286 1IR1 CAP 0.03121 0.4075
287 2JF9 OHT 0.02167 0.40741
288 1L6O SER LEU LYS LEU MET THR THR VAL 0.04575 0.40738
289 1ZFJ IMP 0.03179 0.40712
290 1ZFJ IMP 0.03179 0.40712
291 1ZC9 PMP 0.03623 0.40698
292 2HFP NSI 0.02228 0.40685
293 1S17 GNR 0.0372 0.4064
294 2WPX ACO 0.03745 0.40626
295 3OGN 3OG 0.04868 0.40598
296 1RJD SAM 0.03817 0.40585
297 1A78 TDG 0.04652 0.40556
298 2YMZ LAT 0.01834 0.4043
299 4OKX 198 0.02329 0.4036
300 1QPR PPC 0.03343 0.40349
301 3CTL S6P 0.03974 0.40237
302 3CTL S6P 0.03974 0.40237
303 3LLI FAD 0.01996 0.40205
304 1RDT L79 0.0408 0.40181
305 4M8E 29V 0.04145 0.40147
306 3QCP FAD 0.02317 0.40141
307 1T36 U 0.04827 0.40074
308 2ZZ5 6CN 0.04841 0.40068
309 3SXN COA 0.03827 0.40067
310 4Q0A 4OA 0.04847 0.40065
311 4Q0A 4OA 0.04847 0.40065
312 3V49 PK0 0.02727 0.40048
313 4E6D 0NU 0.04922 0.40032
314 2VVS OAN 0.03913 0.40021
315 3D2Y AH0 ALA FGA LYS 0.04957 0.40016
Pocket No.: 2; Query (leader) PDB : 4ORM; Ligand: FMN; Similar sites found: 315
This union binding pocket(no: 2) in the query (biounit: 4orm.bio1) has 60 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1F76 ORO 0.0000000003087 0.93028
2 1F76 FMN 0.00000000000003497 0.92289
3 1F76 FMN 0.00000000000004052 0.92009
4 1F76 FMN 0.00000000000004374 0.91862
5 1F76 FMN 0.00000000000004619 0.91757
6 3OIX FMN 0.000000000009972 0.83326
7 1OVD ORO 0.0000000000001503 0.80769
8 1OVD FMN 0.0000000000001503 0.80769
9 3MJY IJZ 0.000000000000942 0.80734
10 3MJY FMN 0.000000000000942 0.80734
11 3OIX FMN 0.00000000004266 0.80448
12 3OIX FMN 0.00000000004266 0.80448
13 3C3N FMN 0.0000000000004962 0.79531
14 1EP2 FMN 0.0000000001294 0.74983
15 1EP2 ORO 0.0000000000194 0.74061
16 1GTE FMN 0.0000000001644 0.70435
17 1GTE IUR 0.0000000001644 0.70435
18 1GTE FMN 0.0000000002646 0.69023
19 1GTE IUR 0.0000000002646 0.69023
20 4IA6 EIC 0.00003018 0.61636
21 3B0P FMN 0.00001923 0.57974
22 3B0P FMN 0.00002035 0.57849
23 2Q3R FMN 0.00001387 0.56893
24 1Z41 FMN 0.00009629 0.54413
25 1Z41 FMN 0.00009629 0.54413
26 1Z44 FMN 0.000126 0.54384
27 1Z44 FMN 0.000126 0.54384
28 1Z48 FMN 0.00009923 0.54347
29 1Z42 FMN 0.000172 0.54263
30 1Z42 FMN 0.000172 0.54263
31 3QH2 3NM 0.0004224 0.54023
32 3QH2 3NM 0.0005067 0.53574
33 4JEJ 1GP 0.0002321 0.53573
34 4QNW FMN 0.00006267 0.53255
35 3TDC 0EU 0.0005864 0.52873
36 4NAE 1GP 0.001118 0.52128
37 2Q3O FMN 0.000165 0.50836
38 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.003421 0.5074
39 3EXS 5RP 0.001032 0.50661
40 4JIQ FMN 0.000167 0.50395
41 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.00228 0.50179
42 2Q3O FMN 0.0001707 0.49952
43 1NF8 BOG 0.003191 0.4992
44 2HSA FMN 0.00008036 0.49871
45 3W9Z FMN 0.0005143 0.49783
46 4M5P FMN 0.0003696 0.49618
47 3B9Z CO2 0.001731 0.48928
48 1AL8 FMN 0.0003695 0.48823
49 1VYP TNF 0.0003083 0.48801
50 4JIQ 1L5 0.0002609 0.48755
51 1ICP FMN 0.000151 0.48718
52 1KBI PYR 0.000222 0.48702
53 1KBI FMN 0.000222 0.48702
54 3BW2 FMN 0.0001264 0.48701
55 1ICP FMN 0.000172 0.4848
56 3EXS 5RP 0.002269 0.48318
57 2NLI LAC 0.0004828 0.48293
58 2NLI FMN 0.0004828 0.48293
59 2NLI FMN 0.0004828 0.48293
60 2VWA PTY 0.005187 0.48292
61 4EWN 0VR 0.001569 0.48244
62 2Z6I FMN 0.000606 0.48215
63 1VHN FMN 0.002395 0.48193
64 3ATY FMN 0.0005473 0.48045
65 1VYP FMN 0.0003809 0.4803
66 2RDT FMN 0.0004169 0.47857
67 1KBJ FMN 0.0004221 0.47834
68 2F6U CIT 0.00525 0.47801
69 2GJN FMN 0.000466 0.47644
70 2GJN FMN 0.000466 0.47644
71 2WOR 2AN 0.006952 0.47621
72 4UTU LRY 0.002711 0.47458
73 3ATY FMN 0.0006734 0.4728
74 1OYB FMN 0.0008168 0.47252
75 3SP6 IL2 0.001967 0.46929
76 1TRD PGH 0.004156 0.46922
77 1TRD PGH 0.004156 0.46922
78 2O1V ADP 0.005401 0.46758
79 3B6C SDN 0.008705 0.46549
80 2GJN NIS 0.0005867 0.46549
81 2GJN NIS 0.0005867 0.46549
82 1GVF PGH 0.009119 0.46434
83 1AL8 DHP 0.0005703 0.4599
84 2NLI FMN 0.001003 0.45859
85 4V3I ASP LEU THR ARG PRO 0.01435 0.4575
86 2R14 FMN 0.001118 0.45654
87 2Z6J FMN 0.0008431 0.45576
88 2RDT 2RD 0.0006265 0.45532
89 2FDW D3G 0.01094 0.45522
90 2NPA MMB 0.002757 0.45496
91 1B57 PGH 0.009392 0.45451
92 2VWA PTY 0.01741 0.45396
93 1OFD AKG 0.0005026 0.4536
94 3ET1 ET1 0.00418 0.45324
95 2ZRU FMN 0.0003272 0.45284
96 1QDS PGA 0.01011 0.45276
97 1OFD AKG 0.0005369 0.45246
98 2NLI LAC 0.001192 0.45234
99 2NLI LAC 0.001192 0.45234
100 1OYB HBA 0.00145 0.45164
101 3TAO PGH 0.01105 0.45066
102 4HBM 0Y7 0.0132 0.45066
103 4HBM 0Y7 0.0132 0.45066
104 2FLI DX5 0.004042 0.45045
105 3KO0 TFP 0.01253 0.45043
106 1VKF CIT 0.0162 0.45007
107 4M26 AKG 0.01809 0.44958
108 4WLB SER LEU LEU LYS LYS LEU LEU ASP 0.01767 0.44918
109 3KO0 TFP 0.01339 0.44864
110 1Q6O LG6 0.007416 0.44804
111 1Q6O LG6 0.007416 0.44804
112 4OAS 2SW 0.008834 0.44787
113 3KO0 TFP 0.01275 0.44769
114 4BI7 PGA 0.01515 0.44732
115 2BTM PGA 0.01525 0.44716
116 1OFD FMN 0.0005868 0.4457
117 1Q1Y BB2 0.009817 0.44548
118 1SW0 PGA 0.01166 0.44536
119 2VWA PTY 0.0252 0.44524
120 2BYC FMN 0.01001 0.44504
121 3KRU FMN 0.0009633 0.445
122 4I67 G G G RPC 0.01456 0.44412
123 1OFD FMN 0.0006451 0.44412
124 2FLI DX5 0.004715 0.44394
125 3WMX THR 0.003999 0.44351
126 1M2Z BOG 0.02188 0.44296
127 4AF0 IMP 0.004283 0.44273
128 4OKZ 3E9 0.003802 0.44204
129 4I9A NCN 0.008387 0.44176
130 2NPA MMB 0.00386 0.44174
131 2BYC FMN 0.01379 0.44147
132 3O01 DXC 0.03734 0.44115
133 4AF0 IMP 0.004652 0.44107
134 3ET1 ET1 0.009035 0.44014
135 1H5R THM 0.0174 0.43989
136 4MLM TLA 0.02561 0.43953
137 3W54 RNB 0.01286 0.43934
138 4LWU 20U 0.01312 0.4389
139 1DJN FMN 0.004585 0.43833
140 3NV6 CAM 0.008713 0.43822
141 3A2Q ACA ACA 0.009917 0.43811
142 4HBM 0Y7 0.01905 0.43774
143 3FAL REA 0.01403 0.43738
144 3FAL REA 0.01403 0.43738
145 1MT1 AG2 0.03315 0.43698
146 2YFB SIN 0.01365 0.43667
147 3AQT RCO 0.03117 0.43653
148 4Q9N 0WE 0.01494 0.43594
149 3ZGJ RMN 0.02432 0.43581
150 4G8R 96P 0.03295 0.43504
151 4Q9N 0WE 0.01557 0.435
152 3A75 GLU 0.03197 0.43482
153 3VKC FPQ 0.007578 0.43419
154 3A75 GLU 0.03319 0.43404
155 2YLD CMO 0.03227 0.43341
156 4HBM 0Y7 0.02367 0.43257
157 4HBM 0Y7 0.02367 0.43257
158 1LYX PGA 0.01742 0.43246
159 1LYX PGA 0.01742 0.43246
160 2H8Z FMN 0.004046 0.43228
161 4MLM TLA 0.0305 0.43201
162 4MLM TLA 0.0305 0.43201
163 1VKF CIT 0.03391 0.432
164 2R14 TXD 0.002367 0.43174
165 4HBM 0Y7 0.0252 0.43108
166 2WG9 OCA 0.03476 0.43101
167 3FEI CTM 0.008919 0.43083
168 3OVR 5SP 0.007969 0.43019
169 2YPI PGA 0.02627 0.43009
170 2WG9 OCA 0.03645 0.42982
171 3GLC R5P 0.02327 0.42931
172 3GLC R5P 0.02344 0.42914
173 4A3R CIT 0.02035 0.42892
174 1G27 BB1 0.01315 0.42878
175 2VVG ADP 0.0444 0.42874
176 1P4C FMN 0.002838 0.42853
177 1NQ7 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 0.03281 0.42849
178 3P9T TCL 0.02813 0.42845
179 1CX9 NHP 0.00583 0.428
180 4HBM 0Y7 0.02874 0.42794
181 2DBX GLU 0.04281 0.4274
182 2CB8 MYA 0.04317 0.42736
183 1C3X 8IG 0.03219 0.42708
184 4HBM 0Y7 0.03016 0.42679
185 4IBF 1D5 0.02253 0.42659
186 4HBM 0Y7 0.03052 0.42651
187 2H8Z 8CM 0.004802 0.42645
188 1OX5 1PR 0.004845 0.42629
189 3IT6 ORN 0.04169 0.42626
190 1MT1 AG2 0.04279 0.42578
191 3KO0 TFP 0.04062 0.42526
192 1OX5 1PR 0.005143 0.42518
193 1TPY 16A 0.02079 0.42511
194 1SQS TLA 0.04218 0.42503
195 4IBF 1D5 0.02445 0.42473
196 1DKF BMS 0.01063 0.42436
197 2IYG FMN 0.02889 0.42426
198 2D6M LBT 0.02287 0.42383
199 3G58 988 0.03437 0.42366
200 1UJP CIT 0.01928 0.4236
201 2FJK 13P 0.03453 0.42355
202 4HW3 19G 0.03458 0.42352
203 4N6W FLC 0.03019 0.42324
204 1YRX FMN 0.02293 0.42291
205 4F4S EFO 0.0484 0.42267
206 1WDD CAP 0.01529 0.42257
207 1NU4 MLA 0.04312 0.4224
208 1NU4 MLA 0.04312 0.4224
209 1K7L 544 0.00906 0.42211
210 2PRG BRL 0.02064 0.42211
211 3ZGJ RMN 0.04982 0.42194
212 1SDW IYT 0.0321 0.42179
213 1K7L 544 0.008088 0.42171
214 4IXH IMP 0.01061 0.42166
215 1XN0 ROL 0.04375 0.42142
216 2C6Q IMP 0.009467 0.42126
217 3G58 988 0.0384 0.421
218 3LBZ Z89 0.0479 0.42084
219 2C6Q IMP 0.009677 0.42083
220 2PX6 DH9 0.02531 0.4207
221 3FEA ACE PHE MET AIB PM3 6CW GLU 1AC LEU NH2 0.03944 0.42036
222 1K7L 544 0.008772 0.42015
223 2V68 CAP 0.0172 0.42009
224 2V63 CAP 0.01513 0.41994
225 3VGL ANP 0.02645 0.41972
226 3RK0 AMP 0.03538 0.41952
227 2V67 CAP 0.01565 0.41924
228 1RBL CAP 0.0139 0.41892
229 4HW3 19G 0.04191 0.4189
230 4C2G ALA ALA ALA ALA 0.0489 0.41868
231 2GOU FMN 0.003836 0.41858
232 3W54 RNB 0.02455 0.4183
233 2G50 ALA 0.04327 0.41813
234 2GTE VA 0.01274 0.41802
235 2VDH CAP 0.01666 0.41794
236 3VV1 GAL FUC 0.04266 0.41755
237 2TPS TPS 0.01005 0.41753
238 2TPS TPS 0.01011 0.41742
239 1UZH CAP 0.01723 0.41725
240 2CIX CEJ 0.04144 0.41691
241 1IR2 CAP 0.01761 0.41679
242 3B99 U51 0.0399 0.41669
243 1DE6 RNS 0.04004 0.41661
244 1K7L 544 0.01064 0.41643
245 1UZD CAP 0.01805 0.41629
246 4HW3 19G 0.0354 0.41625
247 4WCK API 0.02696 0.41625
248 3G58 988 0.04696 0.41616
249 1S17 GNR 0.02387 0.41599
250 3CR3 ADP 0.02101 0.41587
251 1IR2 CAP 0.01849 0.41579
252 1ULE GLA GAL NAG 0.03749 0.41565
253 1T0S BML 0.03323 0.41515
254 1T0S BML 0.03323 0.41515
255 4OAR 2S0 0.02197 0.41493
256 2BJ4 OHT 0.02223 0.41469
257 2JGV ADP 0.04362 0.41459
258 4J2V DIU 0.02594 0.41419
259 3RET PYR 0.03887 0.4141
260 3RET SAL 0.03887 0.4141
261 3SIX GDP 0.04456 0.41409
262 3SIX GDP 0.04456 0.41409
263 2UZ1 TPP 0.01211 0.41394
264 2QCD U5P 0.02307 0.4139
265 4RC7 PL3 0.03434 0.41386
266 3CR3 ADP 0.02401 0.41305
267 1TIQ COA 0.04069 0.41305
268 3CR3 ADP 0.02401 0.41305
269 2AKO ADP 0.03608 0.41275
270 4EKQ NPO 0.03182 0.4126
271 4EKQ NPO 0.03182 0.4126
272 1S8G DAO 0.04823 0.41223
273 1TIQ COA 0.03697 0.4122
274 4OAS 2SW 0.02922 0.41162
275 3M31 FAD 0.01799 0.41113
276 3M31 FAD 0.01799 0.41113
277 3GAY P6T 0.0265 0.41097
278 1YRX FMN 0.04485 0.4108
279 3D78 NBB 0.02082 0.41071
280 4MPN PV0 0.0169 0.4099
281 3RV5 DXC 0.04622 0.40955
282 4HBM 0Y7 0.02561 0.40904
283 3VV1 GAL FUC 0.0442 0.40899
284 4NB5 2JT 0.03372 0.40853
285 2OL1 UMP 0.0437 0.40842
286 1IR1 CAP 0.03121 0.4075
287 2JF9 OHT 0.02167 0.40741
288 1L6O SER LEU LYS LEU MET THR THR VAL 0.04575 0.40738
289 1ZFJ IMP 0.03179 0.40712
290 1ZFJ IMP 0.03179 0.40712
291 1ZC9 PMP 0.03623 0.40698
292 2HFP NSI 0.02228 0.40685
293 1S17 GNR 0.0372 0.4064
294 2WPX ACO 0.03745 0.40626
295 3OGN 3OG 0.04868 0.40598
296 1RJD SAM 0.03817 0.40585
297 1A78 TDG 0.04652 0.40556
298 2YMZ LAT 0.01834 0.4043
299 4OKX 198 0.02329 0.4036
300 1QPR PPC 0.03343 0.40349
301 3CTL S6P 0.03974 0.40237
302 3CTL S6P 0.03974 0.40237
303 3LLI FAD 0.01996 0.40205
304 1RDT L79 0.0408 0.40181
305 4M8E 29V 0.04145 0.40147
306 3QCP FAD 0.02317 0.40141
307 1T36 U 0.04827 0.40074
308 2ZZ5 6CN 0.04841 0.40068
309 3SXN COA 0.03827 0.40067
310 4Q0A 4OA 0.04847 0.40065
311 4Q0A 4OA 0.04847 0.40065
312 3V49 PK0 0.02727 0.40048
313 4E6D 0NU 0.04922 0.40032
314 2VVS OAN 0.03913 0.40021
315 3D2Y AH0 ALA FGA LYS 0.04957 0.40016
Pocket No.: 3; Query (leader) PDB : 4ORM; Ligand: 2V6; Similar sites found: 337
This union binding pocket(no: 3) in the query (biounit: 4orm.bio1) has 61 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 1F76 ORO 0.0000000003248 0.93028
2 1F76 FMN 0.0000000000000383 0.92289
3 1F76 FMN 0.0000000000000443 0.92009
4 1F76 FMN 0.00000000000004785 0.91862
5 1F76 FMN 0.00000000000005052 0.91757
6 3OIX FMN 0.00000000001076 0.83326
7 1OVD ORO 0.0000000000001664 0.80769
8 1OVD FMN 0.0000000000001664 0.80769
9 3MJY FMN 0.000000000001032 0.80734
10 3MJY IJZ 0.000000000001032 0.80734
11 3OIX FMN 0.00000000004588 0.80448
12 3OIX FMN 0.00000000004588 0.80448
13 3C3N FMN 0.0000000000005467 0.79531
14 1EP2 FMN 0.0000000001395 0.74983
15 1EP2 ORO 0.00000000002116 0.74061
16 1GTE FMN 0.0000000001783 0.70435
17 1GTE IUR 0.0000000001783 0.70435
18 1GTE FMN 0.0000000002871 0.69023
19 1GTE IUR 0.0000000002871 0.69023
20 4IA6 EIC 0.00003123 0.61636
21 3B0P FMN 0.00002003 0.57974
22 3B0P FMN 0.0000212 0.57849
23 2Q3R FMN 0.00001273 0.57165
24 1Z48 FMN 0.00008891 0.54674
25 1Z42 FMN 0.0001659 0.54428
26 1Z42 FMN 0.0001659 0.54428
27 1Z44 FMN 0.0001286 0.5442
28 1Z44 FMN 0.0001286 0.5442
29 1Z41 FMN 0.0001 0.54413
30 1Z41 FMN 0.0001 0.54413
31 3QH2 3NM 0.0004359 0.54023
32 3QH2 3NM 0.0005228 0.53574
33 4JEJ 1GP 0.0002403 0.53573
34 4QNW FMN 0.00006534 0.53255
35 3TDC 0EU 0.0006007 0.52873
36 4NAE 1GP 0.001151 0.52128
37 2Q3O FMN 0.0001496 0.51116
38 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.003508 0.5074
39 3EXS 5RP 0.001065 0.50661
40 4JIQ FMN 0.0001816 0.50311
41 2HSA FMN 0.00006822 0.50255
42 2Q3O FMN 0.0001535 0.50241
43 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 0.002343 0.50179
44 4M5P FMN 0.0002962 0.50151
45 2WOR 2AN 0.002705 0.49967
46 1NF8 BOG 0.003274 0.4992
47 3W9Z FMN 0.0005332 0.49783
48 1ICP FMN 0.0001186 0.49243
49 1VYP TNF 0.000293 0.4898
50 3B9Z CO2 0.001774 0.48928
51 1AL8 FMN 0.0003843 0.48823
52 4JIQ 1L5 0.000265 0.48805
53 3BW2 FMN 0.0001274 0.48769
54 1ICP FMN 0.0001575 0.48723
55 1KBI FMN 0.0002317 0.48702
56 1KBI PYR 0.0002317 0.48702
57 2Z6I FMN 0.0005618 0.48445
58 3ATY FMN 0.0004768 0.48395
59 3EXS 5RP 0.00234 0.48318
60 2NLI FMN 0.0005019 0.48293
61 2NLI LAC 0.0005019 0.48293
62 2NLI FMN 0.0005019 0.48293
63 2VWA PTY 0.005311 0.48292
64 4EWN 0VR 0.001621 0.48244
65 1VYP FMN 0.0003589 0.48223
66 1VHN FMN 0.00247 0.48193
67 2RDT FMN 0.0004342 0.47857
68 1KBJ FMN 0.0004396 0.47834
69 2F6U CIT 0.005395 0.47801
70 2GJN FMN 0.0004796 0.47667
71 2GJN FMN 0.0004796 0.47667
72 3ATY FMN 0.0005837 0.47635
73 1OYB FMN 0.0007233 0.47568
74 4UTU LRY 0.002797 0.47458
75 3SP6 IL2 0.002034 0.46929
76 1TRD PGH 0.004281 0.46922
77 1TRD PGH 0.004281 0.46922
78 2O1V ADP 0.005558 0.46758
79 3B6C SDN 0.008479 0.4668
80 2GJN NIS 0.0005858 0.46628
81 2GJN NIS 0.0005858 0.46628
82 1GVF PGH 0.009362 0.46434
83 1AL8 DHP 0.0005859 0.46018
84 2NLI FMN 0.001043 0.45859
85 4V3I ASP LEU THR ARG PRO 0.0147 0.4575
86 2Z6J FMN 0.0008369 0.45665
87 2R14 FMN 0.001189 0.45612
88 2RDT 2RD 0.000651 0.4554
89 1OYB HBA 0.001237 0.45537
90 2FDW D3G 0.01123 0.45522
91 2NPA MMB 0.002852 0.45496
92 1B57 PGH 0.009653 0.45451
93 2VWA PTY 0.01782 0.45396
94 1OFD AKG 0.0005256 0.4536
95 2ZRU FMN 0.0003432 0.45284
96 1QDS PGA 0.01039 0.45276
97 1OFD AKG 0.0005613 0.45246
98 2NLI LAC 0.00124 0.45234
99 2NLI LAC 0.00124 0.45234
100 3AIH BMA MAN MAN 0.01705 0.4507
101 2HHP FLC 0.003067 0.45069
102 3TAO PGH 0.01135 0.45066
103 4HBM 0Y7 0.01355 0.45066
104 4HBM 0Y7 0.01355 0.45066
105 2FLI DX5 0.004176 0.45045
106 1VKF CIT 0.01659 0.45007
107 4M26 AKG 0.01854 0.44958
108 4WLB SER LEU LEU LYS LYS LEU LEU ASP 0.01811 0.44918
109 3KO0 TFP 0.0137 0.44864
110 1Q6O LG6 0.00764 0.44804
111 1Q6O LG6 0.00764 0.44804
112 4OAS 2SW 0.009091 0.44787
113 4BI7 PGA 0.01555 0.44732
114 2BTM PGA 0.01565 0.44716
115 1OFD FMN 0.0006142 0.4457
116 1SW0 PGA 0.01199 0.44536
117 2VWA PTY 0.02578 0.44524
118 2BYC FMN 0.0103 0.44504
119 3KRU FMN 0.001005 0.445
120 4I67 G G G RPC 0.01496 0.44412
121 1OFD FMN 0.000675 0.44412
122 2FLI DX5 0.004874 0.44394
123 3WMX THR 0.004094 0.44351
124 1M2Z BOG 0.02233 0.44296
125 4AF0 IMP 0.004431 0.44273
126 4I9A NCN 0.008642 0.44176
127 2NPA MMB 0.003996 0.44174
128 2BYC FMN 0.01418 0.44147
129 3O01 DXC 0.03806 0.44115
130 4AF0 IMP 0.004811 0.44107
131 4OKZ 3E9 0.004172 0.44089
132 4RC7 PL3 0.01084 0.44026
133 3ET1 ET1 0.009309 0.44014
134 4MLM TLA 0.02621 0.43953
135 3W54 RNB 0.01323 0.43934
136 4LWU 20U 0.01349 0.4389
137 1DJN FMN 0.004705 0.4385
138 3NV6 CAM 0.008908 0.43822
139 3A2Q ACA ACA 0.01022 0.43811
140 4HBM 0Y7 0.01955 0.43774
141 1MT1 AG2 0.03391 0.43698
142 2YFB SIN 0.01395 0.43667
143 3AQT RCO 0.03189 0.43653
144 4Q9N 0WE 0.01536 0.43594
145 3ZGJ RMN 0.02493 0.43581
146 4Q9N 0WE 0.01601 0.435
147 2R14 TXD 0.002053 0.43499
148 3A75 GLU 0.03273 0.43482
149 3VGL ANP 0.01387 0.43477
150 3VKC FPQ 0.007824 0.43419
151 2YLD CMO 0.03301 0.43341
152 4HBM 0Y7 0.02428 0.43257
153 4HBM 0Y7 0.02428 0.43257
154 1LYX PGA 0.0179 0.43246
155 1LYX PGA 0.0179 0.43246
156 2H8Z FMN 0.004195 0.43228
157 4MLM TLA 0.0312 0.43201
158 4MLM TLA 0.0312 0.43201
159 1VKF CIT 0.0347 0.432
160 1TIQ COA 0.01836 0.43188
161 3L0E G58 0.004367 0.43152
162 3L0E G58 0.004367 0.43152
163 4HBM 0Y7 0.02585 0.43108
164 2WG9 OCA 0.03559 0.43101
165 3FEI CTM 0.009206 0.43083
166 2GTE VA 0.006988 0.43063
167 3OVR 5SP 0.008232 0.43019
168 2YPI PGA 0.02695 0.43009
169 2WG9 OCA 0.03732 0.42982
170 3GLC R5P 0.02389 0.42931
171 3GLC R5P 0.02406 0.42914
172 3RS8 ALA TRP LEU PHE GLU ALA 0.01547 0.42904
173 4A3R CIT 0.0209 0.42892
174 2VVG ADP 0.04536 0.42874
175 1P4C FMN 0.002952 0.42853
176 3P9T TCL 0.02885 0.42845
177 1CX9 NHP 0.006037 0.428
178 4HBM 0Y7 0.02947 0.42794
179 1G27 BB1 0.01643 0.42773
180 2DBX GLU 0.04379 0.4274
181 1TIQ COA 0.01953 0.42712
182 1C3X 8IG 0.03291 0.42708
183 3KO0 TFP 0.04735 0.42703
184 4HBM 0Y7 0.03093 0.42679
185 4IBF 1D5 0.02315 0.42659
186 4HBM 0Y7 0.03129 0.42651
187 2H8Z 8CM 0.00498 0.42645
188 1OX5 1PR 0.005024 0.42629
189 3IT6 ORN 0.04264 0.42626
190 2BWM SNG 0.04027 0.42588
191 3GAY P6T 0.01356 0.42573
192 2ZFI ADP 0.03236 0.42571
193 1OX5 1PR 0.005333 0.42518
194 3IX9 MTX 0.0285 0.42518
195 1TPY 16A 0.02137 0.42511
196 3IL6 B83 0.01397 0.42509
197 1SQS TLA 0.04309 0.42503
198 4IBF 1D5 0.02511 0.42473
199 4HW3 19G 0.03379 0.42466
200 1DKF BMS 0.01097 0.42436
201 2IYG FMN 0.02964 0.42426
202 4OKW 198 0.01692 0.424
203 3CHT 4NB 0.04857 0.42398
204 2D6M LBT 0.02336 0.42383
205 3G58 988 0.03523 0.42366
206 1UJP CIT 0.01983 0.4236
207 2FJK 13P 0.0354 0.42355
208 3C56 PH4 0.01504 0.42354
209 1YRX FMN 0.02357 0.42291
210 1WDD CAP 0.01575 0.42257
211 1NU4 MLA 0.04394 0.4224
212 1NU4 MLA 0.04394 0.4224
213 2PRG BRL 0.02123 0.42211
214 1K7L 544 0.009367 0.42211
215 1K7L 544 0.008368 0.42171
216 4IXH IMP 0.01096 0.42166
217 1XN0 ROL 0.0448 0.42142
218 1SDW IYT 0.0336 0.42133
219 2C6Q IMP 0.009786 0.42126
220 3G58 988 0.03936 0.421
221 3LBZ Z89 0.04896 0.42084
222 2C6Q IMP 0.01 0.42083
223 2GOU FMN 0.003522 0.42075
224 2PX6 DH9 0.02601 0.4207
225 4DR9 BB2 0.02616 0.42057
226 3FEA ACE PHE MET AIB PM3 6CW GLU 1AC LEU NH2 0.04042 0.42036
227 1K7L 544 0.009074 0.42015
228 2V68 CAP 0.01772 0.42009
229 2V63 CAP 0.01559 0.41994
230 2V67 CAP 0.01613 0.41924
231 1RBL CAP 0.01434 0.41892
232 3W54 RNB 0.02524 0.4183
233 2G50 ALA 0.04434 0.41813
234 4HBM 0Y7 0.01713 0.41799
235 2VDH CAP 0.01717 0.41794
236 4Q0A GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 0.03939 0.41759
237 3VV1 GAL FUC 0.04356 0.41755
238 2TPS TPS 0.0104 0.41753
239 2WPX ACO 0.02291 0.41748
240 2TPS TPS 0.01046 0.41742
241 1UZH CAP 0.01775 0.41725
242 4HW3 19G 0.04652 0.41697
243 1IR2 CAP 0.01815 0.41679
244 1K7L 544 0.011 0.41643
245 1UZD CAP 0.0186 0.41629
246 3G58 988 0.04811 0.41616
247 3CR3 ADP 0.02163 0.41587
248 1IR2 CAP 0.01906 0.41579
249 4OAR 2S0 0.02205 0.41546
250 1T0S BML 0.03395 0.41515
251 1T0S BML 0.03395 0.41515
252 2BJ4 OHT 0.02288 0.41469
253 2JGV ADP 0.04472 0.41459
254 3OGN 3OG 0.03445 0.41438
255 4RC7 PL3 0.02647 0.41436
256 3RET PYR 0.03988 0.4141
257 3RET SAL 0.03988 0.4141
258 3SIX GDP 0.04568 0.41409
259 3SIX GDP 0.04568 0.41409
260 3IX9 MTX 0.03064 0.41404
261 2UZ1 TPP 0.01252 0.41394
262 2QCD U5P 0.02381 0.41384
263 4MG8 27J 0.04053 0.41372
264 4HW3 19G 0.02411 0.41358
265 1WS1 BB2 0.03642 0.41313
266 3CR3 ADP 0.02472 0.41305
267 3CR3 ADP 0.02472 0.41305
268 2AKO ADP 0.03704 0.41275
269 4EKQ NPO 0.0327 0.4126
270 4EKQ NPO 0.0327 0.4126
271 1S8G DAO 0.04943 0.41223
272 4NES UDP 0.03338 0.41214
273 4J2V DIU 0.02978 0.41182
274 4OAS 2SW 0.03005 0.41162
275 2VAT COA 0.03474 0.41127
276 3M31 FAD 0.01856 0.41113
277 3M31 FAD 0.01856 0.41113
278 1OSV CHC 0.03093 0.411
279 1YRX FMN 0.046 0.4108
280 3D78 NBB 0.02146 0.41071
281 2PIA FMN 0.02777 0.41058
282 4MPN PV0 0.01744 0.4099
283 1NQ7 ARL 0.02901 0.40965
284 2CIX CEJ 0.04589 0.40944
285 3FAL LO2 0.009783 0.40933
286 1Q1Y BB2 0.04946 0.40912
287 3VV1 GAL FUC 0.04513 0.40899
288 4NB5 2JT 0.03466 0.40853
289 2OL1 UMP 0.04485 0.40842
290 1IR1 CAP 0.0321 0.4075
291 2JF9 OHT 0.02235 0.40741
292 1L6O SER LEU LYS LEU MET THR THR VAL 0.04695 0.40738
293 1ZFJ IMP 0.0327 0.40712
294 1ZFJ IMP 0.0327 0.40712
295 3OGN 3OG 0.04209 0.40702
296 1ZC9 PMP 0.03723 0.40698
297 1E4I NFG 0.0484 0.40698
298 1QPR PPC 0.02948 0.40672
299 2HFP NSI 0.02351 0.40639
300 4HR0 PLM 0.01877 0.40611
301 1RJD SAM 0.03922 0.40585
302 1A78 TDG 0.04749 0.40556
303 3UDZ ADP 0.04021 0.40531
304 3R5W F42 0.04067 0.40506
305 3KFC 61X 0.01247 0.40493
306 3FAL LO2 0.01123 0.40472
307 3FAL LO2 0.01123 0.40472
308 3R5W F42 0.04144 0.40465
309 4POJ 2VP 0.0257 0.4046
310 2R40 20E 0.02297 0.40448
311 2R40 20E 0.02297 0.40448
312 4RC8 STE 0.03296 0.40439
313 2YMZ LAT 0.01873 0.4043
314 2Q4V ACO 0.02086 0.40406
315 3TAX UDP 0.01038 0.40404
316 3TAX UDP 0.01038 0.40404
317 2X7B COA 0.0235 0.40403
318 4OKX 198 0.0236 0.40394
319 3R5W F42 0.04326 0.40371
320 1Q23 FUA 0.03876 0.40349
321 3R5W F42 0.04396 0.40337
322 3SXN COA 0.03487 0.40321
323 3IPQ 965 0.01389 0.40298
324 3R5W F42 0.04487 0.40292
325 2CNT COA 0.03998 0.40283
326 3LLI FAD 0.01979 0.40283
327 3CTL S6P 0.04085 0.40237
328 3CTL S6P 0.04085 0.40237
329 3QCP FAD 0.02329 0.40192
330 3V49 PK0 0.02699 0.40129
331 3UDZ ADP 0.0494 0.40082
332 3UDZ ADP 0.0494 0.40082
333 3R5W F42 0.0494 0.40082
334 1T36 U 0.04957 0.40074
335 2ZZ5 6CN 0.04972 0.40068
336 2VVS OAN 0.04025 0.40021
337 4FHH 0U3 0.01036 0.40012
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