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Receptor
PDB id Resolution Class Description Source Keywords
3WXM 2.3 Å EC: 3.1.-.- CRYSTAL STRUCTURE OF ARCHAEAL PELOTA AND GTP-BOUND EF1 ALPHA AEROPYRUM PERNIX K1 MRNA SURVEILLANCE RIBOSOME TRANSLATION-HYDROLASE COMPLEX
Ref.: STRUCTURAL BASIS FOR MRNA SURVEILLANCE BY ARCHAEAL AND GTP-BOUND EF1 ALPHA COMPLEX PROC.NATL.ACAD.SCI.USA V. 107 17575 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:502;
C:502;
G:502;
E:502;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
GTP A:501;
G:501;
C:501;
E:501;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3WXM 2.3 Å EC: 3.1.-.- CRYSTAL STRUCTURE OF ARCHAEAL PELOTA AND GTP-BOUND EF1 ALPHA AEROPYRUM PERNIX K1 MRNA SURVEILLANCE RIBOSOME TRANSLATION-HYDROLASE COMPLEX
Ref.: STRUCTURAL BASIS FOR MRNA SURVEILLANCE BY ARCHAEAL AND GTP-BOUND EF1 ALPHA COMPLEX PROC.NATL.ACAD.SCI.USA V. 107 17575 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 19 families.
1 3WXM - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 3WXM - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 3WXM - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 156
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 9GM 0.809524 0.973684
9 GNP 0.809524 0.973684
10 GCP 0.797619 0.973684
11 5GP 0.797468 0.986486
12 G 0.797468 0.986486
13 GMV 0.764706 0.973684
14 G2R 0.764045 0.961039
15 G5P 0.755319 0.973684
16 GTG 0.752688 0.936709
17 G2P 0.747126 0.961039
18 G3A 0.744681 0.973684
19 GDD 0.741935 0.961039
20 GDC 0.741935 0.961039
21 GKE 0.741935 0.961039
22 0O2 0.736264 0.986486
23 GP2 0.729412 0.961039
24 6CK 0.726316 0.936709
25 Y9Z 0.723404 0.902439
26 GPG 0.717391 0.961039
27 GFB 0.715789 0.961039
28 GDR 0.715789 0.961039
29 GPD 0.704082 0.925
30 GKD 0.693878 0.961039
31 JB2 0.693878 0.961039
32 GDX 0.686869 0.973684
33 ALF 5GP 0.685393 0.888889
34 GH3 0.681319 0.973333
35 YGP 0.677083 0.901235
36 G3D 0.67033 0.986486
37 GDP AF3 0.659574 0.888889
38 ALF GDP 0.659574 0.888889
39 GDP ALF 0.659574 0.888889
40 DGT 0.659341 0.923077
41 GMP 0.658228 0.88
42 G4P 0.655914 0.986486
43 JB3 0.653846 0.948718
44 NGD 0.647619 0.961039
45 CAG 0.642202 0.880952
46 2MD 0.62963 0.891566
47 MGP 0.619565 0.961039
48 U2G 0.616822 0.936709
49 6G0 0.612903 0.961039
50 MGD 0.612613 0.891566
51 TPG 0.608696 0.840909
52 CG2 0.605505 0.936709
53 GDP 7MG 0.601942 0.911392
54 FEG 0.601852 0.879518
55 G G 0.598039 0.948052
56 ZGP 0.59633 0.869048
57 PGD 0.591304 0.925
58 MD1 0.591304 0.891566
59 3GP 0.590909 0.946667
60 GPX 0.581633 0.946667
61 DGI 0.580645 0.923077
62 IDP 0.576087 0.972973
63 DBG 0.567797 0.948718
64 2GP 0.555556 0.96
65 FE9 0.555556 0.776596
66 G4M 0.547619 0.880952
67 BGO 0.544643 0.924051
68 GCP G 0.543689 0.921053
69 ATP 0.537634 0.92
70 HEJ 0.537634 0.92
71 G1G 0.533898 0.925
72 AQP 0.531915 0.92
73 5FA 0.531915 0.92
74 A G 0.525862 0.935065
75 G A A A 0.525862 0.923077
76 U A G G 0.521368 0.935065
77 HFD 0.520833 0.873418
78 R5I 0.520408 0.946667
79 R7I 0.520408 0.946667
80 01G 0.518868 0.902439
81 P2G 0.510638 0.883117
82 ITT 0.510638 0.868421
83 AKW 0.504348 0.890244
84 GGM 0.504274 0.901235
85 G1R G1R 0.504065 0.924051
86 DGP 0.5 0.910256
87 PGD O 0.5 0.850575
88 MGO 0.5 0.864198
89 DG 0.5 0.910256
90 P1G 0.5 0.871795
91 GTA 0.495495 0.936709
92 PRT 0.490741 0.959459
93 B4P 0.489362 0.894737
94 AP5 0.489362 0.894737
95 IMP 0.489362 0.959459
96 G U 0.487179 0.9
97 7DT 0.484536 0.906667
98 GPC 0.479339 0.879518
99 G C 0.478992 0.9
100 BA3 0.478723 0.894737
101 ADP 0.473684 0.92
102 G2Q 0.471698 0.961039
103 6YZ 0.470588 0.896104
104 G7M 0.46875 0.948052
105 C1Z 0.462963 0.986486
106 25L 0.458716 0.907895
107 A2D 0.457447 0.894737
108 RGT 0.45045 0.909091
109 AGS 0.45 0.873418
110 SAP 0.45 0.873418
111 SGP 0.44898 0.82716
112 A4P 0.445378 0.869048
113 G G G RPC 0.442623 0.875
114 ANP 0.441176 0.896104
115 ACQ 0.441176 0.896104
116 8GT 0.441176 0.875
117 APC G U 0.44 0.886076
118 AT4 0.438776 0.884615
119 G U34 0.438017 0.888889
120 6AD 0.436893 0.841463
121 G G G C 0.433071 0.9125
122 UP5 0.432203 0.873418
123 PCG 0.431373 0.933333
124 C2E 0.431373 0.921053
125 35G 0.431373 0.933333
126 A G C C 0.429688 0.911392
127 T99 0.427184 0.884615
128 5GP 5GP 0.427184 0.883117
129 TAT 0.427184 0.884615
130 AR6 0.425743 0.894737
131 APR 0.425743 0.894737
132 7DD 0.424242 0.906667
133 AN2 0.424242 0.907895
134 DG DG 0.423423 0.865854
135 AD9 0.421569 0.896104
136 M33 0.42 0.883117
137 7D4 0.42 0.835443
138 UCG 0.419847 0.911392
139 HDV 0.419048 0.825
140 H6Y 0.419048 0.946667
141 G C C C 0.416667 0.924051
142 ACP 0.415842 0.896104
143 T5A 0.414634 0.802326
144 A1R 0.412844 0.839506
145 ADQ 0.412844 0.871795
146 MGQ 0.412844 0.935897
147 A3R 0.412844 0.839506
148 MGT 0.411215 0.823529
149 A G U 0.410072 0.888889
150 93A 0.41 0.833333
151 A22 0.407407 0.907895
152 CA0 0.405941 0.896104
153 ATF 0.40566 0.884615
154 AGO 0.404762 0.888889
155 MGV 0.401786 0.890244
156 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3WXM; Ligand: GTP; Similar sites found with APoc: 676
This union binding pocket(no: 1) in the query (biounit: 3wxm.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4IDN GNP 1.59574
2 2G50 ALA 1.8617
3 6CZY PMP 1.9337
4 1RRC ADP 1.99336
5 5H4S RAM 2.11268
6 4A4Z ANP 2.12766
7 1TQ4 GDP 2.17918
8 1XP8 AGS 2.18579
9 1V8K ANP 2.19512
10 2XT3 ADP 2.32558
11 4IOK XPO 2.39362
12 4IOK ADP 2.39362
13 1PSC EBP 2.46575
14 1F9V ADP 2.59366
15 4JLV ADP 2.60223
16 5I0H ADP BEF 2.65957
17 2BIF ANP 2.65957
18 2BIF SIN 2.65957
19 2XAU ADP 2.68456
20 1YTM ATP 2.68456
21 1OS1 PYR 2.68456
22 1OS1 ATP 2.68456
23 2OWZ CIT 2.71084
24 1QF5 RPL 2.78422
25 1QF5 GDP 2.78422
26 3ZFD ANP 2.849
27 1R6B ADP 2.92553
28 1IHU ADP 2.92553
29 1IHU AF3 2.92553
30 1G3Q ADP 2.95359
31 2PL3 ADP 2.9661
32 1DAK DPU 3.125
33 1DAK ADP 3.125
34 4LHD GLY 3.13199
35 1IWE IMP 3.13199
36 5CK5 GDP 3.16456
37 3GJ3 GDP 3.16742
38 3GJ0 GDP 3.16742
39 5K5Z ANP 3.18471
40 4LYA ATP 3.19149
41 2DPY ADP 3.19149
42 5VHC BEF ADP 3.19149
43 3UYW TAU 3.27103
44 2Y65 ADP 3.28767
45 6CS8 F9Y 3.30033
46 3BOS CDP 3.30579
47 4AG5 ADP 3.31633
48 1JI0 ATP 3.33333
49 4IV9 TSR 3.3557
50 3MD0 GDP 3.38028
51 4WZ6 ATP 3.44828
52 5LTJ ADP 3.45745
53 3TBK ANP 3.45745
54 2ZPA ADP 3.45745
55 5LTJ BEF 3.45745
56 5I34 GDP 3.45745
57 4BFW ZVW 3.45912
58 2W58 ADP 3.46535
59 4AP9 1PS 3.48259
60 4L77 CNL 3.51759
61 3COB ADP 3.52304
62 1LVG ADP 3.53535
63 2Q2Y ADP 3.54223
64 2Q2Y MKR 3.54223
65 2ZFI ADP 3.55191
66 5LV1 78T 3.57143
67 2IS6 ADP 3.57942
68 1P4V GLY 3.57942
69 4TVD BGC 3.57942
70 2D2F ADP 3.6
71 3FVQ ATP 3.62117
72 1YQT ADP 3.7234
73 1F5N GNP 3.7234
74 3FKQ ATP 3.75335
75 3EZ2 ADP 3.76884
76 1M7G AV2 3.79147
77 1M7G ADP 3.79147
78 1M7G ADX 3.79147
79 1NY5 ADP 3.80313
80 1X6V ADP 3.80313
81 6DEF GCP 3.83632
82 4D81 ADP 3.88693
83 1G6H ADP 3.89105
84 3B7G ANP 3.91304
85 3LRE ADP 3.94366
86 1WA5 GTP 3.97727
87 5XJ7 87O 3.9801
88 5L3V GDP 4.01338
89 4L80 OXL 4.02299
90 3QDK QDK 4.02685
91 5HR5 ADP 4.02685
92 6CBO DOW 4.02685
93 5LB3 ADP 4.04494
94 3GJ4 GDP 4.0724
95 3GJ5 GDP 4.0724
96 3QXC ATP 4.13223
97 2OG2 MLI 4.17827
98 1B0U ATP 4.19847
99 3GJX GTP 4.25056
100 5KSZ GCP 4.25056
101 4H1V GNP 4.25056
102 1PUJ GNP 4.25532
103 2FAH GDP 4.25532
104 3FYH ADP 4.34783
105 3P4X ADP 4.35835
106 2PZE ATP 4.36681
107 1JJV ATP 4.36893
108 5H68 AGS 4.41176
109 6G14 G4P 4.42177
110 3BFV ADP 4.42804
111 3VX3 ADP 4.43548
112 4GOX A3P 4.47284
113 1P72 ADP 4.49102
114 1U0J ADP 4.49438
115 1S8F GDP 4.51977
116 4IHQ ADP 4.52128
117 4OHY ANP 4.52128
118 6B4K ANP 4.52128
119 2FSH ANP 4.52128
120 4YS0 ADP 4.52128
121 4PPF FLC 4.57143
122 5HCN GCP 4.5977
123 4MKF AP5 4.60829
124 5EXT ADP 4.61538
125 6FA4 GNP 4.62428
126 3FB4 AP5 4.62963
127 3DC4 ADP 4.65116
128 3QKT ANP 4.71976
129 1M2O GNP 4.73684
130 1BO4 COA 4.7619
131 5GOE GDP 4.78723
132 1XKV ATP 4.78723
133 4KVA GTP 4.78723
134 3CV2 OXL 4.78723
135 2C9O ADP 4.78723
136 6FAA ADP 4.78723
137 1SVK ALF GDP 4.81586
138 1W5T ANP 4.85437
139 1W5T ADP 4.85437
140 5G3Y ADP 4.86726
141 1IBR GNP 4.9217
142 3B9Q MLI 4.96689
143 2RCN GDP 5.02793
144 2WKQ GTP 5.05319
145 1RYH GNP 5.05319
146 4V03 ADP 5.05837
147 1CR1 TTP 5.06757
148 4RZ3 ADP 5.08475
149 2VVG ADP 5.14286
150 5XDR ADP 5.14541
151 3TK1 GDP 5.15152
152 6H5E ANP 5.17928
153 2OBM ADP 5.18732
154 1SQ5 ADP 5.19481
155 2OM2 GDP 5.23077
156 1XX6 ADP 5.2356
157 5C9P FUC 5.24934
158 5Y6N ADP 5.25114
159 2WW4 ADP 5.30035
160 2GDJ ANP 5.30303
161 4IEE AGS 5.31915
162 1D8C GLV 5.31915
163 1P7T PYR 5.31915
164 2J5V PCA 5.31915
165 1ION ADP 5.34979
166 5G6U TRP 5.36398
167 1MH1 GNP 5.37634
168 4HDO GNP 5.38922
169 3X1Z GNP 5.38922
170 1IN4 ADP 5.38922
171 4NE2 SH2 5.38922
172 4NE2 ADP 5.38922
173 1BH2 GSP 5.39683
174 2X7I CIT 5.51948
175 1FZQ GDP 5.52486
176 2G77 GDP 5.55556
177 1TAD GDP 5.55556
178 1TAD ALF 5.55556
179 2G77 AF3 5.55556
180 1SVM ATP 5.57029
181 4TTQ ATP 5.5814
182 5YV5 ADP 5.58511
183 4R43 GDP 5.58511
184 3RC3 ANP 5.58511
185 2O0J ADP 5.58511
186 2GKS ADP 5.58511
187 2Y8E GNP 5.58659
188 4YJ1 ADP 5.59284
189 1OYY AGS 5.59284
190 2FJU GSP 5.61798
191 3AB4 THR 5.61798
192 6B8B ADP 5.62249
193 2IYL GDP 5.6338
194 4QOS ADP 5.66038
195 5E5U MLI 5.68182
196 1NRJ GTP 5.6962
197 1KO8 6PG 5.71429
198 5JCP GDP ALF 5.72792
199 1Z0A GDP 5.74713
200 3TNF GNP 5.74713
201 4LHW GNP 5.74713
202 1A4R GNH 5.75916
203 1A4R GDP 5.75916
204 5A9A UTP 5.76132
205 5KSP GDP 5.78947
206 1VG8 GNP 5.7971
207 1VG0 GDP 5.7971
208 3E7S AT2 5.81656
209 1Z06 GNP 5.82011
210 5OCG GNP 5.82011
211 5IRR GSP 5.84416
212 4HSE ADP 5.85106
213 5IFS ADP 5.85106
214 3HU3 AGS 5.85106
215 2FNA ADP 5.88235
216 4L9Z OXL 5.8997
217 2CBZ ATP 5.90717
218 1HE1 GDP 5.92593
219 1HE1 AF3 5.92593
220 1H65 GDP 5.92593
221 4FRZ ADP 5.95855
222 1W7J ADP BEF 5.96026
223 1FWV SGA MAG FUC 5.97015
224 1Y63 ADP 5.97826
225 1ZIN AP5 5.99078
226 1KY3 GDP 6.04396
227 4OI4 ATP 6.08696
228 2B8W ALF 5GP 6.09756
229 5M04 GDP 6.11111
230 2NCD ADP 6.11702
231 5ZXD ATP 6.11702
232 4ZDJ UTP 6.11702
233 3GJ7 GDP 6.12245
234 4PVR ASP 6.12903
235 4WEI GLC GAL 6.13718
236 4U00 ADP 6.14754
237 3PCR GTP 6.17284
238 4LJ9 ACP 6.19469
239 1K6M AGS 6.25
240 3RWO GDP 6.26398
241 5G41 AP5 6.27803
242 2ODE ALF GDP 6.28571
243 2RGX AP5 6.31068
244 1WF3 GNP 6.31229
245 5J1J ANP 6.31579
246 1XPJ TLA 6.34921
247 3FWY ADP 6.36943
248 2OZE AGS 6.37584
249 5WC2 ADP 6.38298
250 1P9B GDP 6.38298
251 1P9B HDA 6.38298
252 4QDI ATP 6.38298
253 5WDR GNP 6.43275
254 1S3G AP5 6.45161
255 1VG1 GDP 6.48649
256 1VG9 GDP 6.48649
257 4PX9 ADP 6.50685
258 3RAB GNP 6.50888
259 1NN5 2DT 6.51163
260 1NN5 ANP 6.51163
261 2ZEJ GDP 6.52174
262 3EWA ANP 6.52174
263 3DZD ADP 6.52174
264 3Q9L ATP 6.53846
265 4X8O AP5 6.54206
266 4XFR CIT 6.55738
267 3B5J 12D 6.58436
268 6D5E GNP 6.58683
269 6D5G GNP 6.58683
270 6D5J GNP 6.58683
271 6D5H GNP 6.58683
272 6BVJ GNP 6.58683
273 6BVK GNP 6.58683
274 6D55 GNP 6.58683
275 6D56 GNP 6.58683
276 6D59 GNP 6.58683
277 6D5L GNP 6.58683
278 6BVL GNP 6.58683
279 6BVI GNP 6.58683
280 6D5M GNP 6.58683
281 6BVM GNP 6.58683
282 6D5V GNP 6.58683
283 2ZR9 DTP 6.59026
284 2J0V GDP 6.60377
285 1NVV GNP 6.62651
286 1CLU DBG 6.62651
287 1WQ1 GDP 6.62651
288 1WQ1 AF3 6.62651
289 2EFE GNH 6.62983
290 4LPS GDP 6.64894
291 4XGU ADP 6.64894
292 5VGR GDP 6.64894
293 1LVK MNT BEF 6.64894
294 2ZJ5 ADP 6.64894
295 2O66 FLC 6.66667
296 4LX0 BEF GDP 6.71141
297 1OIV GDP 6.71141
298 1Z6T ADP 6.71141
299 3CPJ GDP 6.72646
300 5F1V 3VN 6.73401
301 2A5F GTP 6.73575
302 4FCW ADP 6.75241
303 3N5C GDP 6.79012
304 5MVR ADP 6.79012
305 5Z2M GTP 6.81818
306 1AKY AP5 6.81818
307 2WMO GTP 6.84211
308 2QEN ADP 6.85714
309 3W5J GDP 6.86275
310 1OW3 GDP 6.91489
311 1YZN GNP 6.93512
312 5TAR GDP 6.93512
313 2BCG GDP 6.93512
314 1FNN ADP 6.94087
315 1E2K TMC 6.94864
316 4XZ3 ACP 6.95652
317 2GJ8 ALF GDP 6.97674
318 2BEK ATP 7.00389
319 1XMV ADP 7.02247
320 4D0N GDP 7.02703
321 6BC0 GSP 7.02703
322 3LXR GDP 7.02703
323 1KMQ GNP 7.06522
324 2AWN ADP 7.08661
325 1I4D GDP 7.14286
326 2WHX ADP 7.18085
327 2JLR ANP 7.18085
328 1KK8 BEF ADP 7.19424
329 1NJF AGS 7.2
330 1NJF ADP 7.2
331 5XQL C2E 7.2165
332 4XOI GTP 7.22222
333 3T34 GDP 7.22222
334 1L2T ATP 7.23404
335 1Z0F GDP 7.26257
336 1G6O ADP 7.27273
337 5L3R GCP 7.30897
338 1G4U GDP 7.31071
339 1G4U AF3 7.31071
340 5MZN ADP 7.44681
341 5H67 ATP 7.44681
342 5BN3 ADP 7.45192
343 5UIV ADP 7.48899
344 2CHG ANP 7.52212
345 1SQL GUN 7.53425
346 6CRK GDP 7.53623
347 2QG6 NMN 7.53769
348 4K81 GTP 7.60234
349 4DDY DN6 7.60456
350 1M7B GTP 7.6087
351 1G16 GDP 7.64706
352 1GOT GDP 7.64706
353 5KDO GDP 7.64706
354 1GP2 GDP 7.64706
355 1B7T ADP 7.69231
356 5JCZ GDP 7.71277
357 4PJ3 ANP 7.71277
358 4KVG GTP 7.7381
359 3IIJ ADP 7.77778
360 1YZG GDP 7.82123
361 2WIC GNP 7.86517
362 3O7J 2AL 7.93651
363 2HF9 GSP 7.9646
364 4CP8 MLI 7.97872
365 1YRB GDP 8.01527
366 1ZJ6 G3D 8.02139
367 1D5C GDP 8.02469
368 3FIU POP 8.03213
369 4R98 GNH 8.11808
370 2QTV GNP 8.16327
371 2OFW ADX 8.17308
372 2FFQ GSP 8.18713
373 3PQC GDP 8.20513
374 2VB6 ADP BEF 8.24468
375 4PFO ADP 8.24468
376 3KJI ADP 8.26772
377 5NM7 GLY 8.27068
378 1T5C ADP 8.2774
379 5TSH ANP 8.2774
380 5TSH ADP 8.2774
381 4E3Q PMP 8.2774
382 3Q85 GNP 8.28402
383 4NU0 AP5 8.29493
384 4YMU ATP 8.33333
385 5BQ5 ADP BEF 8.46561
386 2CDC XYS 8.46994
387 1CS4 GSP 8.49057
388 5FTB ANP 8.51064
389 5FHD ADP ALF 8.51064
390 5GVR LMR 8.54701
391 4R2I ANP 8.57143
392 4Q1A UDP 8.57143
393 4Q1A 2XZ 8.57143
394 1FP6 ADP 8.65052
395 5BXQ GDP 8.66142
396 5TB5 GDP 8.66667
397 2C5L GTP 8.67052
398 3EC1 GDP 8.67209
399 4XSH GSP 8.6758
400 3E70 GDP 8.72483
401 2QQ0 ANP 8.72483
402 2QQ0 TMP 8.72483
403 2QQ0 ADP 8.72483
404 2WOJ ADP ALF 8.75706
405 4XTR ATP 8.75706
406 4XVU ATP 8.75706
407 4XTR ADP 8.75706
408 1VKJ A3P 8.77193
409 2QZ4 ADP 8.77863
410 3T5G GDP 8.83978
411 3H4S ADP 8.88889
412 1ZUI SKM 8.92857
413 4U5X GNP 8.98876
414 3E5H GNP 8.98876
415 6BSX GDP 8.98876
416 6BSX E7S 8.98876
417 5KUT GDP 8.99471
418 5HPY GDP 9.05172
419 4WZA ACP 9.05797
420 4WZA ADP 9.05797
421 1UJ2 ADP 9.12698
422 1UJ2 C5P 9.12698
423 3CNL GNP 9.16031
424 5M7P ADP 9.17226
425 3TKL GTP 9.18367
426 3QBT GNP 9.28571
427 2CE7 ADP 9.30851
428 1TU3 GNP 9.35672
429 1R2Q GNP 9.41177
430 4DCT GDP 9.42982
431 2EW1 GNP 9.45274
432 3NHB ADP 9.47712
433 4ZNL BEF ADP 9.48905
434 5XKT GNP 9.5
435 3MJH GTP 9.52381
436 5N69 ADP 9.54774
437 2IXE ATP 9.5941
438 2UZI GTP 9.61539
439 4YDS ATP 9.64912
440 2BME GNP 9.67742
441 4DKX GDP 9.72222
442 1SVI GDP 9.74359
443 4WOP CTP 9.77778
444 3AQ4 GDP 9.78261
445 5UWP GNP 9.79021
446 6CIT GNP 9.79021
447 5DHF GNP 9.79021
448 5UWQ GNP 9.79021
449 5UWT GNP 9.79021
450 5UWH GNP 9.79021
451 5DIF GNP 9.79021
452 5UWW GNP 9.79021
453 5UWI GNP 9.79021
454 5UWJ GNP 9.79021
455 5UWR GNP 9.79021
456 5DI9 GNP 9.79021
457 3RLF ANP 9.84043
458 1GXU 2HP 9.89011
459 4KAX GTP 9.93789
460 3SFV GDP 9.94475
461 1MR3 G3D 9.94475
462 1OIX GDP 9.94764
463 5O74 GDP 10
464 4HAT GNP 10
465 3QF7 ANP 10
466 3UIE ANP 10
467 3ITJ CIT 10.0592
468 1Z2A GDP 10.119
469 5L3W GDP 10.1307
470 1Z0J GTP 10.1695
471 4BQS ADP 10.2273
472 4BQS K2Q 10.2273
473 1GWN GTP 10.2439
474 6BCB GSP 10.274
475 3NKV GNP 10.2857
476 1RJ9 GCP 10.3333
477 6AU6 GDP 10.3448
478 4KFU ACP 10.3774
479 1GOJ ADP 10.4225
480 1G8S MET 10.4348
481 2GCO GNP 10.4478
482 2GCN GDP 10.4478
483 5L3S GNP 10.473
484 5L3S G 10.473
485 3M1I GTP 10.5023
486 3WYF GTP 10.5023
487 4ZI2 GNP 10.5263
488 3ZS9 ADP ALF 10.5263
489 4HI0 GDP 10.5528
490 1G41 ADP 10.5856
491 5U32 GDP 10.5932
492 1APZ ASP 10.6383
493 1D2N ANP 10.6383
494 1QHG ATP 10.6383
495 4KBF AMP 10.6849
496 3DEF GDP 10.687
497 1Z83 AP5 10.7143
498 4P4T GDP 10.7383
499 1F2U ATP 10.7383
500 1JJ7 ADP 10.7692
501 2VWT PYR 10.8614
502 3GJ8 GDP 10.8696
503 3IO3 ADP 10.9195
504 1RE0 GDP 10.9756
505 1S9D GDP 10.9756
506 2A5J GDP 10.9948
507 5SZH GNP 11.1111
508 5UQW GDP 11.1111
509 4ZG4 VO4 ADP 11.1702
510 6A20 ADP 11.2128
511 4C4P GNP 11.215
512 2A9K GDP 11.2299
513 2XTZ GSP 11.2994
514 1KAO GDP 11.3772
515 2CJW GDP 11.4583
516 1VHT BA3 11.4679
517 5OEC GDP 11.4754
518 3LN9 FLC 11.5108
519 4CVN ADP 11.5183
520 4MKG AP5 11.5207
521 3CH5 GDP 11.5385
522 2XTN GTP 11.5385
523 6C90 ADP 11.5385
524 1UPT GTP 11.6667
525 1C9K 5GP 11.6667
526 1ZD9 GDP 11.7021
527 2BO4 FLC 11.7021
528 2PEZ DAT 11.7318
529 2PEZ GGZ 11.7318
530 5WLB GNP 11.7647
531 1YZQ GNP 11.7647
532 1Z08 GNP 11.7647
533 1UAD GNP 12
534 4ITR GDP 12.0419
535 2NGR GDP 12.0419
536 2NGR AF3 12.0419
537 2VHJ ADP 12.0846
538 5LEF GTP 12.1212
539 1W0J ADP 12.234
540 1W0J ADP BEF 12.234
541 3DDC GNP 12.2699
542 3SBD GNP 12.2995
543 1TE2 PGA 12.3894
544 4DID GDP 12.4352
545 2CDN ADP 12.4378
546 2HV8 GTP 12.5
547 1U8Z GDP 12.5
548 5AK0 8V1 12.5
549 3BFX A3P 12.5
550 6BCA GSP 12.5828
551 2HT6 GDP 12.6437
552 1HTW ADP 12.6582
553 4Y4V DAL 12.6844
554 2Q37 3AL 12.7072
555 3KTA AP5 12.7168
556 4M9Q GNP 12.7753
557 1GRN GDP 12.8079
558 1GRN AF3 12.8079
559 3R7F CP 12.8289
560 5Z69 AGS 12.9032
561 1R0X ATP 12.9754
562 2W83 GTP 12.987
563 2V7Q ADP 13.0137
564 2CK3 ANP 13.0137
565 2V7Q ATP 13.0137
566 2CK3 ADP 13.0137
567 5ZBR ANP 13.0667
568 1TX4 ALF GDP 13.1313
569 5O2J 2PO 13.1868
570 3Q72 GNP 13.253
571 2J59 GTP 13.253
572 1O3Y GTP 13.253
573 2GK6 ADP 13.2979
574 2YOH WMJ 13.3333
575 4NTX AMR 13.3333
576 3REF GDP 13.4021
577 4E03 ADP 13.5922
578 5XC5 GTP 13.6364
579 5ZB0 ADP 13.6364
580 5ZB0 TYD 13.6364
581 3A4M ADP 13.8462
582 1OXV ANP 13.881
583 2KIN ADP 14
584 4YC7 GNP 14.0957
585 4PU6 ASP 14.2132
586 4QRH 0O2 14.2857
587 1WDT GTP 14.3177
588 5X40 ACP 14.3836
589 5E95 GDP 14.433
590 5H9I XAN 14.5833
591 1DAR GDP 14.7651
592 1GUA GNP 14.8148
593 3KUD GDP 14.8148
594 5DI3 GNP 14.8289
595 5IRC GDP 14.9254
596 1FQJ ALF 14.966
597 1FQK ALF 14.966
598 1FQJ GDP 14.966
599 1FQK GDP 14.966
600 3H86 AP5 15.1042
601 4QM7 GTP 15.2047
602 3BC1 GNP 15.2542
603 2W2X GSP 15.3226
604 2FH5 GTP 15.4206
605 3AB3 GDP 15.4696
606 1ZCB GDP 15.4696
607 1OFH ADP 15.4839
608 5EE5 GTP 15.493
609 1KSH GDP 15.5914
610 3CX8 GSP 15.9763
611 4NON GDP 16.1538
612 3DKP ADP 16.3265
613 3ZIA ATP 16.3934
614 3ZIA ADP 16.3934
615 1E96 GTP 16.6667
616 1EK0 GNP 17.0588
617 4BAS GNP 17.0854
618 4D0G GTP 17.3913
619 2X77 GDP 17.4603
620 4GOJ GNP 17.5
621 1QF9 C5P 18.0412
622 1QF9 ADP 18.0412
623 1QF9 ALF 18.0412
624 1LFD GNP 18.3908
625 2P7Q GG6 18.797
626 5IRN ADP 18.883
627 2D7C GTP 19.0476
628 4YLG GDP 19.0751
629 1MKY GDP 19.1344
630 3TD3 GLY 19.5122
631 5H7K GDP 19.6809
632 2WJG GDP 19.6809
633 5H7J GCP 19.6809
634 4LC1 GDP 19.8813
635 5UWO GNP 20
636 1X1R GDP 20.2247
637 1Z0K GTP 20.2899
638 1DS6 GDP 20.3125
639 1ZC3 GNP 20.354
640 3A1S GDP 20.5426
641 2F9L GDP 20.603
642 2WJH FLC 21.0843
643 2WJH GDP 21.0843
644 1BG2 ADP 21.2308
645 3ZQ6 ADP ALF 21.2963
646 1R4A GNP 21.5686
647 5J1S ATP 21.9512
648 1J2J GTP 22.2222
649 1NF3 GNP 22.6562
650 1F6B GDP 22.7273
651 5UWS GNP 22.7273
652 3T12 GDP ALF 22.7273
653 3T1O GDP 22.7273
654 5O2T GSP 22.9947
655 3DOE GTP 23.6364
656 3CYI ATP 23.6364
657 1YVD GNP 23.6686
658 3WYG GTP 23.6842
659 4RD0 GDP 23.8554
660 1G7S GDP 23.9374
661 5UWU GNP 25
662 5UPK GNP 25
663 2ZTS ADP 25.8964
664 4NCN GTP 26.3982
665 4TMZ GSP 26.3982
666 4HDQ GNP 26.9231
667 1CXZ GSP 27.907
668 5FG3 GDP 29.9776
669 4ZKD GDP 30.4251
670 4V0K GDP 32.5444
671 2VOH CIT 34.6154
672 4B47 GDP 34.7107
673 5YT0 GDP 35.989
674 1Y3A GDP 37.5
675 1KK1 GNP 38.5366
676 4J0Q GDP 47.1132
Pocket No.: 2; Query (leader) PDB : 3WXM; Ligand: GTP; Similar sites found with APoc: 26
This union binding pocket(no: 2) in the query (biounit: 3wxm.bio4) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 2OAT PFM 2.05011
2 3VSV XYP 2.65957
3 4NZ6 DGL 2.8754
4 1Z5U CMP 3.27103
5 3FSY SCA 3.91566
6 3EF0 ALF 4.03226
7 3OCP CMP 4.31655
8 3PNA CMP 4.54545
9 5KGS 6SR 5.58511
10 4TL6 ANP 5.59284
11 5JVB 2PO 5.71429
12 1UKZ ADP 5.91133
13 4FBL SPD 6.04982
14 1QXA GLY GLY GLY 6.38298
15 2UVO NAG 6.43275
16 3TMK T5A 7.87037
17 6ACS CIT 8.13953
18 2V2G BEZ 8.15451
19 2QQ0 THM 8.72483
20 1INN MET 9.03614
21 1DNP MHF 9.04255
22 4O48 ASP 11.1446
23 5KBF CMP 11.9601
24 4CQM NAP 13.0268
25 3KPB SAM 13.1148
26 3BY9 SIN 15
Pocket No.: 3; Query (leader) PDB : 3WXM; Ligand: GTP; Similar sites found with APoc: 15
This union binding pocket(no: 3) in the query (biounit: 3wxm.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 1MLY ACZ PLP 2.7972
2 4ADC PLP 2.95567
3 3ZL8 ADP 3.43249
4 6EGU 43Y 3.45745
5 1IZC PYR 4.12979
6 4UOX PUT 4.28266
7 4UOX PLP 4.28266
8 1W4R TTP 5.12821
9 1IGW PYR 5.52995
10 1AQU A3P 7.07071
11 1GJW GLC 7.15884
12 3VPD BUA 7.47331
13 4GN8 ASO 13.3779
14 1RJW ETF 15.3392
15 4UXH T5A 23.913
Pocket No.: 4; Query (leader) PDB : 3WXM; Ligand: GTP; Similar sites found with APoc: 15
This union binding pocket(no: 4) in the query (biounit: 3wxm.bio3) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 2X1L ADN 2.48092
2 4GYS MLI 2.65957
3 1T9D P22 2.92553
4 2FYF PLP 3.45745
5 6HL7 CP 4.31034
6 2RNF UM3 5.05319
7 1PJS SAH 5.31915
8 1NST A3P 5.84615
9 3IUY AMP 6.14035
10 2ZX2 RAM 7.17949
11 3LA3 2FT 9.0535
12 3FJG 3PG 9.56175
13 2XOM GAL GAL GAL 10.5263
14 2IL4 COA 10.6796
15 5CSS G3P 12.8319
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