Receptor
PDB id Resolution Class Description Source Keywords
3WV0 2.3 Å EC: 1.14.13.39 O-GLYCAN ATTACHED TO HERPES SIMPLEX VIRUS TYPE 1 GLYCOPROTEI RECOGNIZED BY THE IG V-SET DOMAIN OF HUMAN PAIRED IMMUNOGLOT YPE 2 RECEPTOR ALPHA HOMO SAPIENS IMMUNOGLOBULIN-LIKE IMMUNOLOGICAL RECEPTOR MEMBRANE MEMBRPROTEIN
Ref.: STRUCTURAL BASIS FOR SIMULTANEOUS RECOGNITION OF AN AND ITS ATTACHED PEPTIDE OF MUCIN FAMILY BY IMMUNE PILR ALPHA PROC.NATL.ACAD.SCI.USA V. 111 8877 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 A:202;
B:205;
B:202;
B:203;
A:203;
B:204;
B:201;
A:201;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
 submit data
96.063 O4 S [O-]S...
GLY PRO ALA THR PRO ALA PRO A2G SIA Y:51;
X:50;
 Valid;
Valid;
 none;
none;
 submit data
1103.12 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5XOF 1.96 Å EC: 1.14.13.39 CRYSTAL STRUCTURE OF HUMAN PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 ALPHA WITH SYNTHESIZED GLYCOPEPTIDE I HOMO SAPIENS MEMBRANE PROTEIN IMMUNE RECEPTOR VIRAL ENTRY INHIBITOR GLYCOPEPTIDE IMMUNE SYSTEM
Ref.: STRUCTURAL AND THERMODYNAMIC ANALYSES REVEAL CRITIC FEATURES OF GLYCOPEPTIDE RECOGNITION BY THE HUMAN P IMMUNE CELL RECEPTOR. J. BIOL. CHEM. V. 292 21128 2017
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 5XOF Kd = 120.6 uM GLY PRO ALA THR PRO ALA PRO NDG SIA n/a n/a
2 3WV0 - GLY PRO ALA THR PRO ALA PRO A2G SIA n/a n/a
3 5XO2 Kd = 97.1 uM GLY PRO ALA THR PRO ALA PRO 8B9 SIA n/a n/a
4 4NFD - SIA C11 H19 N O9 CC(=O)N[C@....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 5XOF Kd = 120.6 uM GLY PRO ALA THR PRO ALA PRO NDG SIA n/a n/a
2 3WV0 - GLY PRO ALA THR PRO ALA PRO A2G SIA n/a n/a
3 5XO2 Kd = 97.1 uM GLY PRO ALA THR PRO ALA PRO 8B9 SIA n/a n/a
4 4NFD - SIA C11 H19 N O9 CC(=O)N[C@....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 5XOF Kd = 120.6 uM GLY PRO ALA THR PRO ALA PRO NDG SIA n/a n/a
2 3WV0 - GLY PRO ALA THR PRO ALA PRO A2G SIA n/a n/a
3 5XO2 Kd = 97.1 uM GLY PRO ALA THR PRO ALA PRO 8B9 SIA n/a n/a
4 4NFD - SIA C11 H19 N O9 CC(=O)N[C@....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GLY PRO ALA THR PRO ALA PRO A2G SIA; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 GLY PRO ALA THR PRO ALA PRO A2G SIA 1 1
2 GLY PRO ALA THR PRO ALA PRO 8B9 SIA 0.701863 1
3 A2G THR ALA PRO GLY GLY NAG SIA 0.524324 1
4 ASP SER THR THR PRO ALA PRO THR NGA 0.460227 0.971014
5 BGC GAL SIA 0.417722 0.73913
6 GAL SIA 0.406897 0.724638
7 GAL NAG GAL SIA 0.4 0.768116
Similar Ligands (3D)
Ligand no: 1; Ligand: GLY PRO ALA THR PRO ALA PRO A2G SIA; Similar ligands found: 1
No: Ligand Similarity coefficient
1 GLY PRO ALA THR PRO ALA PRO NDG SIA 0.9240
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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