-->
Receptor
PDB id Resolution Class Description Source Keywords
3WG4 1.6 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF AGROCYBE CYLINDRACEA GALECTIN MUTANT (N BLOOD TYPE A ANTIGEN TETRAOSE AGROCYBE CYLINDRACEA GALECTIN GALACTOSE BINDING SUGAR BINDING PROTEIN
Ref.: CONFORMATIONAL CHANGE OF A UNIQUE SEQUENCE IN A FUN GALECTIN FROM AGROCYBE CYLINDRACEA CONTROLS GLYCAN LIGAND-BINDING SPECIFICITY. FEBS LETT. V. 587 3620 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PEG B:201;
Invalid;
none;
submit data
106.12 C4 H10 O3 C(COC...
A2G GAL NAG FUC A:201;
B:202;
Valid;
Valid;
none;
none;
submit data
732.686 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3WG3 1.35 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF AGROCYBE CYLINDRACEA GALECTIN WITH BLOO ANTIGEN TETRAOSE AGROCYBE CYLINDRACEA GALECTIN GALACTOSE BINDING SUGAR BINDING PROTEIN
Ref.: CONFORMATIONAL CHANGE OF A UNIQUE SEQUENCE IN A FUN GALECTIN FROM AGROCYBE CYLINDRACEA CONTROLS GLYCAN LIGAND-BINDING SPECIFICITY. FEBS LETT. V. 587 3620 2013
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 3WG4 - A2G GAL NAG FUC n/a n/a
2 3WG3 - A2G GAL NAG FUC n/a n/a
3 3WG1 - LAT C12 H22 O11 C([C@@H]1[....
70% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2ZGN - GAL C6 H12 O6 C([C@@H]1[....
2 3M3O Kd = 250.63 uM GAL A2G NPO n/a n/a
3 3M3E Kd = 37.45 uM GAL A2G NPO n/a n/a
4 3M3Q - GAL NGA GAL BGC SIA n/a n/a
5 3AFK Kd = 251.89 uM GAL A2G THR n/a n/a
6 3M3C Kd = 86.21 uM GAL A2G NPO n/a n/a
7 2ZGM - LAT C12 H22 O11 C([C@@H]1[....
8 2ZGO - LAT C12 H22 O11 C([C@@H]1[....
9 3WG4 - A2G GAL NAG FUC n/a n/a
10 3WG3 - A2G GAL NAG FUC n/a n/a
11 3WG1 - LAT C12 H22 O11 C([C@@H]1[....
12 1WW4 - GLA GLC SIA n/a n/a
13 1WW6 - GAL BGC n/a n/a
14 1WW5 - SGA BGC n/a n/a
50% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2ZGN - GAL C6 H12 O6 C([C@@H]1[....
2 3M3O Kd = 250.63 uM GAL A2G NPO n/a n/a
3 3M3E Kd = 37.45 uM GAL A2G NPO n/a n/a
4 3M3Q - GAL NGA GAL BGC SIA n/a n/a
5 3AFK Kd = 251.89 uM GAL A2G THR n/a n/a
6 3M3C Kd = 86.21 uM GAL A2G NPO n/a n/a
7 2ZGM - LAT C12 H22 O11 C([C@@H]1[....
8 2ZGO - LAT C12 H22 O11 C([C@@H]1[....
9 3WG4 - A2G GAL NAG FUC n/a n/a
10 3WG3 - A2G GAL NAG FUC n/a n/a
11 3WG1 - LAT C12 H22 O11 C([C@@H]1[....
12 1WW4 - GLA GLC SIA n/a n/a
13 1WW6 - GAL BGC n/a n/a
14 1WW5 - SGA BGC n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: A2G GAL NAG FUC; Similar ligands found: 169
No: Ligand ECFP6 Tc MDL keys Tc
1 A2G GAL NAG FUC 1 1
2 FUC GAL NAG A2G 1 1
3 A2G GAL BGC FUC 0.809524 0.938776
4 FUC GAL NAG A2G FUC 0.770115 1
5 NAG GAL FUC FUC A2G 0.770115 1
6 GLC FUC GAL FUC A2G 0.755814 0.959184
7 BGC FUC GAL FUC A2G 0.755814 0.959184
8 FUC GAL NDG 0.703704 0.938776
9 DR2 0.703704 0.938776
10 FUL GAL NAG 0.703704 0.938776
11 FUC GAL NAG 0.703704 0.938776
12 NAG GAL FUC 0.703704 0.938776
13 NDG GAL FUC 0.703704 0.938776
14 GAL NAG FUC 0.703704 0.938776
15 GLC GAL NAG GAL FUC A2G 0.683673 1
16 A2G GAL NAG FUC GAL GLC 0.683673 1
17 NAG GDL 0.675325 0.979592
18 CBS CBS 0.675325 0.979592
19 NDG NAG 0.675325 0.979592
20 CBS 0.675325 0.979592
21 FUC GLA A2G 0.674699 0.938776
22 FUC GAL A2G 0.674699 0.938776
23 A2G GAL FUC 0.674699 0.938776
24 A2G GLA FUC 0.674699 0.938776
25 NGA GAL FUC 0.674699 0.938776
26 NAG FUC 0.662338 0.897959
27 NAG GAL NAG 0.647059 0.979592
28 NAG NAG NAG NDG 0.641975 1
29 NAG NAG NAG NAG NAG 0.641975 1
30 NAG NAG NAG NAG NDG 0.641975 1
31 NAG NAG NAG NAG NAG NAG 0.641975 1
32 NDG NAG NAG 0.641975 1
33 NDG NAG NAG NDG 0.641975 1
34 NAG NAG NDG NAG 0.641975 1
35 NAG NAG NDG 0.641975 1
36 NAG NAG NAG NAG NAG NAG NAG NAG 0.641975 1
37 CTO 0.641975 1
38 NDG NAG NAG NAG 0.641975 1
39 BGA 0.62766 0.824561
40 FUC BGC GAL NAG 0.595745 0.938776
41 GLA GAL NAG FUC GAL GLC 0.584158 0.938776
42 BGC GLA GAL FUC 0.579545 0.693878
43 NLC 0.555556 0.918367
44 NDG GAL 0.555556 0.918367
45 GAL NDG 0.555556 0.918367
46 NAG GAL GAL NAG 0.554348 0.979592
47 GAL NAG GAL NAG GAL NAG 0.554348 1
48 NAG BMA NAG MAN MAN NAG NAG 0.537736 1
49 MAN BMA NAG 0.534091 0.918367
50 GLA GAL NAG 0.534091 0.918367
51 FUC NDG GAL FUC 0.532609 0.959184
52 GAL NAG FUC FUC 0.532609 0.959184
53 BDZ 0.532609 0.959184
54 FUC GAL NAG FUC 0.532609 0.959184
55 BCW 0.532609 0.959184
56 FUC GAL NDG FUC 0.532609 0.959184
57 FUC NAG GAL FUC 0.532609 0.959184
58 GAL NDG FUC FUC 0.532609 0.959184
59 NAG MAN BMA NDG MAN NAG GAL 0.53211 1
60 FUC BGC GAL NAG GAL 0.529412 0.938776
61 DR3 0.527473 0.938776
62 NAG NAG BMA MAN MAN NAG GAL NAG 0.527273 1
63 M5G 0.527273 0.979592
64 FUC GAL NAG GAL BGC 0.519608 0.938776
65 GLC NAG GAL GAL FUC 0.519608 0.938776
66 GAL GLC NAG GAL FUC 0.519608 0.938776
67 SN5 SN5 0.511628 0.811321
68 NGA GAL BGC 0.511111 0.918367
69 FUC NDG GAL 0.505495 0.938776
70 GAL NDG FUC 0.505495 0.938776
71 NAG MAN BMA 0.505495 0.918367
72 NAG GAL BGC 0.505376 0.918367
73 NAG A2G 0.5 0.979592
74 TCG 0.5 0.844828
75 NAG NGA 0.5 0.979592
76 NGA GLA GAL BGC 0.494845 0.918367
77 BGC GAL FUC 0.488636 0.693878
78 FUC GAL GLC 0.488636 0.693878
79 8B7 0.488636 0.693878
80 GLC GAL FUC 0.488636 0.693878
81 LAT FUC 0.488636 0.693878
82 GAL NAG 0.488372 0.918367
83 NAG GAL 0.488372 0.918367
84 NAG MAN MAN MAN NAG GAL NAG GAL 0.486239 1
85 MAN BMA NAG NAG MAN NAG GAL GAL 0.486239 1
86 BGC GAL NAG GAL FUC FUC 0.485981 0.959184
87 GLC GAL NAG GAL FUC FUC 0.485981 0.959184
88 FUC GAL NAG GAL FUC 0.485149 0.959184
89 NAG MAN MMA 0.483871 0.92
90 GAL NGA A2G 0.483516 0.979592
91 A2G MBG 0.477273 0.92
92 MBG A2G 0.477273 0.92
93 MAN MAN NAG 0.473684 0.882353
94 NAG NAG BMA MAN MAN 0.471698 0.979592
95 G6S NAG 0.468085 0.707692
96 FUC NAG 0.466667 0.849057
97 NAG MBG 0.465909 0.92
98 NAG MAN MAN MAN NAG 0.465347 0.979592
99 NAG AMU 0.463918 0.98
100 NAG MUB 0.463918 0.98
101 NAG MAN BMA MAN NAG GAL 0.463636 0.979592
102 GLA NAG GAL FUC 0.46 0.938776
103 GAL NAG GAL FUC 0.46 0.938776
104 NAG NAG NAG 0.458333 0.924528
105 NAG NAG NAG NAG 0.458333 0.924528
106 NGA GAL 0.455556 0.862745
107 GLA GLA FUC 0.454545 0.693878
108 GAL GAL FUC 0.454545 0.693878
109 LAT NAG GAL 0.454545 0.918367
110 FUC GLA GLA 0.454545 0.693878
111 GLA GAL FUC 0.454545 0.693878
112 GLC GAL NAG GAL 0.454545 0.918367
113 FUC GAL GLA 0.454545 0.693878
114 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.452991 0.979592
115 NAG BDP NAG BDP NAG BDP NAG 0.451923 0.98
116 NAG NDG 0.445652 0.886792
117 NAG NAG 0.445652 0.886792
118 BMA NAG MAN MAN MAN MAN MAN MAN MAN 0.445455 0.918367
119 NAG GAL GAL NAG GAL 0.444444 0.979592
120 MAG FUC GAL 0.442105 0.94
121 GAL NAG MAN 0.442105 0.918367
122 EAG RAM RAM GLC RAM NAG RAM RAM GLC RAM 0.440367 0.98
123 FUC C4W NAG BMA MAN MAN NAG NAG 0.44 0.942308
124 Z4S NAG NAG 0.44 0.924528
125 NAG MAN MAN 0.438776 0.918367
126 UNU GAL NAG 0.435644 0.96
127 FUC BGC GAL 0.433333 0.693878
128 3QL 0.431579 0.90566
129 FUC C4W NAG BMA 0.431193 0.942308
130 DLD 0.43 0.813559
131 NAG BMA MAN MAN MAN MAN 0.429907 0.918367
132 FUC C4W NAG BMA MAN NAG 0.429752 0.942308
133 MMA MAN NAG MAN NAG NAG 0.428571 0.98
134 GAL NAG GAL BGC 0.427184 0.882353
135 NOJ NAG NAG 0.425743 0.857143
136 NOJ NAG NAG NAG 0.425743 0.875
137 BGB 0.424242 0.614035
138 GAL BGC NAG GAL 0.424242 0.918367
139 GAL NAG GAL 0.424242 0.882353
140 NAG MAN 0.423913 0.959184
141 FUC C4W NAG BMA MAN 0.422414 0.942308
142 BGC GAL NAG GAL 0.42 0.918367
143 GAL NAG GAL GLC 0.42 0.918367
144 FUC NAG TA5 0.419048 0.691176
145 FUC NAG GAL 0.418367 0.867925
146 NAG AMU NAG AMV 0.415094 0.960784
147 FUC NAG GLA GAL 0.415094 0.92
148 KPM 0.415094 0.923077
149 NAG NM9 0.414141 0.960784
150 NAG NAG NGT 0.413462 0.830508
151 BMA Z4Y NAG 0.413462 0.9
152 6Y2 0.413462 0.765625
153 HS2 0.412371 0.882353
154 FUC C4W NAG BMA MAN MAN NAG 0.410853 0.942308
155 NGT NAG 0.41 0.813559
156 WZ5 0.409091 0.92
157 NAG NAG BMA 0.405941 0.90566
158 AH0 NAG 0.405941 0.907407
159 NAG NDG BMA 0.405941 0.90566
160 NAG A2G GAL 0.405941 0.979592
161 NAG NAG BMA MAN MAN NAG NAG 0.404959 0.924528
162 GAL NGA GLA BGC GAL 0.403846 0.918367
163 NAG AMU ALA DGL 0.401709 0.907407
164 A2G GAL 0.4 0.918367
165 BEK GAL NAG 0.4 0.859649
166 GAL NGA 0.4 0.918367
167 8VZ 0.4 0.96
168 GAL A2G 0.4 0.918367
169 LEC NGA 0.4 0.765625
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3WG3; Ligand: A2G GAL NAG FUC; Similar sites found with APoc: 362
This union binding pocket(no: 1) in the query (biounit: 3wg3.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5DRB 5FJ None
2 1QKQ MAN None
3 4NV7 COA None
4 2BOS GLA GAL GLC None
5 2BOS GLA GAL None
6 1GP6 SIN None
7 1GP6 QUE None
8 1GP6 DH2 None
9 3LXK MI1 None
10 2UX9 FMN None
11 5TBM 79A None
12 4MNS 2AX None
13 2CM4 RCL None
14 6GWR FEW None
15 2HZQ STR None
16 2G37 FAD None
17 2Z77 HE7 None
18 3Q60 ATP None
19 1KGI T4A None
20 4JH6 FCN None
21 3KV8 FAH None
22 1QIN GIP 1.1236
23 3BZ3 YAM 1.1236
24 3STD MQ0 1.21212
25 3TAY MN0 1.22699
26 5A89 FMN 1.28205
27 5A89 ADP 1.28205
28 5XVG 8FX 1.68539
29 1ZM1 BGC BGC BGC 1.68539
30 6BXI ANP 1.68539
31 4BVA T3 1.68539
32 5UBG PRT 2.21239
33 6GNO XDI 2.22222
34 6D61 4AA 2.24719
35 2G30 ALA ALA PHE 2.24719
36 4N70 2HX 2.24719
37 3TDV GDP 2.24719
38 5LRT ADP 2.24719
39 5W4W 9WG 2.24719
40 6BU0 IHP 2.29008
41 1QY1 PRZ 2.29885
42 2HKA C3S 2.30769
43 4ZSI 4R1 2.33918
44 3TCT 3MI 2.3622
45 1TT8 PHB 2.43902
46 5HA0 LTD 2.5641
47 4ZU4 4TG 2.7027
48 5W1E PHB 2.80899
49 6C1S EFV 2.80899
50 1UNB PN1 2.80899
51 1UNB AKG 2.80899
52 2WA4 069 2.80899
53 5DQ8 FLF 2.80899
54 4RFR RHN 2.80899
55 5OX6 A1Z 2.80899
56 4NW6 2NS 2.80899
57 5VC5 96M 2.80899
58 4HWS 1B3 2.80899
59 2CET PGI 2.80899
60 3NZ1 3NY 2.80899
61 1UU6 BGC BGC BGC BGC 2.80899
62 5A65 TPP 2.80899
63 5YBN AKG 2.80899
64 3P7N FMN 2.80899
65 5SVV FMN 2.91971
66 3T50 FMN 3.125
67 3ZO7 K6H 3.19149
68 2XMY CDK 3.37079
69 5IH9 6BF 3.37079
70 2A1L PCW 3.37079
71 4J36 FAD 3.37079
72 4J36 1HR 3.37079
73 4GJ3 0XP 3.37079
74 4X3R 686 3.37079
75 3PFG TLO 3.37079
76 3PFG SAM 3.37079
77 2VFT SOR 3.37079
78 4QMN DB8 3.37079
79 3IGO ANP 3.37079
80 3LXN MI1 3.37079
81 1Y7P RIP 3.37079
82 5KJW 53C 3.37079
83 4E1Z 0MX 3.37079
84 3LVW GSH 3.37079
85 4OTH DRN 3.37079
86 2B9F ADP 3.37079
87 5LI9 ACP 3.37079
88 5DXT 5H5 3.37079
89 2B9J ADP 3.37079
90 6C0T EE4 3.37079
91 5LI1 ANP 3.37079
92 3FP0 FP0 3.37079
93 2B9H ADP 3.37079
94 1IIU RTL 3.44828
95 6ALW BNV 3.47222
96 6ALW BMJ 3.47222
97 3KFF ZBT 3.7037
98 3KFF XBT 3.7037
99 5F6U 5VK 3.82166
100 2XK9 XK9 3.93258
101 3OV6 MK0 3.93258
102 3TTI KBI 3.93258
103 1ZB6 GST 3.93258
104 1ZB6 DIN 3.93258
105 1IA9 ANP 3.93258
106 1S4M LUM 3.93258
107 5UR1 YY9 3.93258
108 5HCY 60D 3.93258
109 5UR6 8KM 3.93258
110 4MP8 MLI 3.93258
111 4MP8 NAD 3.93258
112 3RGA LSB 3.93258
113 1EWF PC1 3.93258
114 1ERB ETR 3.93258
115 3IES M24 3.93258
116 5UIU 8CG 3.93258
117 4RF7 ARG 3.93258
118 2GQS C2R 3.93258
119 5E70 RCD 3.93258
120 2ZYI STE 3.93258
121 1TQP ATP 3.93258
122 3V8S 0HD 3.93258
123 5OM2 DXT 3.93258
124 1X7D ORN 3.93258
125 3T64 DU3 3.93258
126 4WW8 VD9 3.93258
127 4QDC ASD 3.93258
128 3DJV C3P 4.03226
129 5C9J STE 4.0404
130 5U98 1KX 4.0404
131 2E56 MYR 4.16667
132 4R38 RBF 4.28571
133 4WN5 MVC 4.34783
134 1DZK PRZ 4.4586
135 3MF2 AMP 4.49438
136 5EOB 5QQ 4.49438
137 4H2V AMP 4.49438
138 4WVO 3UZ 4.49438
139 5WL1 D3D 4.49438
140 5WL1 CUY 4.49438
141 5MZI FYK 4.49438
142 5MZI FAD 4.49438
143 3K4Z CBI 4.49438
144 5E2N V14 4.49438
145 2CWH PYC 4.49438
146 2CWH NDP 4.49438
147 3M3R BCD 4.49438
148 6MPT C30 4.49438
149 3PG7 PTY 4.49438
150 4U0W 16G 4.49438
151 4QA8 PJZ 4.49438
152 4U03 GTP 4.49438
153 4FE2 AIR 4.49438
154 2WSI FAD 4.49438
155 1SQI 869 4.49438
156 3N0Y APC 4.49438
157 1GQG DCD 4.49438
158 4ZTE 4RL 4.49438
159 5NKB 8ZT 4.49438
160 5VCV 1N1 4.49438
161 4H3P ANP 4.49438
162 1OFL NGK GCD 4.49438
163 1BHX ASP PHE GLU GLU ILE 4.7619
164 5OO5 UUA 4.83871
165 4IPH 1FJ 4.87805
166 5IXH OTP 4.96894
167 5Y72 DST 5.05618
168 4BJZ P3A 5.05618
169 4BJZ FAD 5.05618
170 5MU6 KFK 5.05618
171 5MU6 MYA 5.05618
172 4F7E 0SH 5.05618
173 4L3L 5FI 5.05618
174 5W10 CMP 5.05618
175 3E2M E2M 5.05618
176 3L8W XAN 5.05618
177 2ART LPA AMP 5.05618
178 5TA6 79D 5.05618
179 5YJS SAL 5.05618
180 3QRC SCR 5.09554
181 2YG2 FLC 5.23256
182 2YG2 S1P 5.23256
183 5FPX GLY SER SER HIS HIS HIS HIS HIS 5.30973
184 5DKK FMN 5.51724
185 1SDW IYT 5.61798
186 6E08 NAP 5.61798
187 3L9R L9R 5.61798
188 3L9R L9Q 5.61798
189 5FBN 5WF 5.61798
190 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 5.61798
191 4KYS VIB 5.61798
192 3FW4 CAQ 5.61798
193 1U0A BGC BGC BGC BGC 5.61798
194 2VQ5 HBA 5.61798
195 3QXQ CE5 5.61798
196 4QDF 30Q 5.61798
197 5FI4 5XV 5.61798
198 3FYS PLM 5.61798
199 5FU3 BGC BGC BGC 5.66038
200 4WUJ FMN 6.12245
201 4YZC STU 6.17978
202 3PE2 E1B 6.17978
203 4P8K FAD 6.17978
204 4P8K 38C 6.17978
205 5FXD H7Y 6.17978
206 3ILR SGN 6.17978
207 3ILR IXD 6.17978
208 1VA6 ADP 6.17978
209 4ITH RCM 6.17978
210 4EE7 PIS 6.17978
211 4P25 FUC GAL NAG FUC 6.17978
212 2OJW ADP 6.17978
213 4DXD 9PC 6.17978
214 4IZY 1J2 6.17978
215 1VA6 P2S 6.17978
216 5HV0 AKG 6.17978
217 4FG8 ATP 6.17978
218 3GC8 B45 6.17978
219 3OZ2 OZ2 6.17978
220 1KHZ ADV 6.17978
221 4RYV ZEA 6.45161
222 4FFG 0U8 6.74157
223 5NEA 8V8 6.74157
224 4QCK ASD 6.74157
225 2YNE YNE 6.74157
226 2YNE NHW 6.74157
227 4CJN QNZ 6.74157
228 5X1M THG 6.74157
229 5W75 SUC 6.74157
230 2YKL NLD 6.74157
231 6GVZ CHO 6.74157
232 2Q4H AMP 6.74157
233 5X1M DHB 6.74157
234 4HWT 1B2 6.74157
235 4NS0 PIO 6.76692
236 5HZX 2GE 6.81818
237 4WUP 3UF 7.30337
238 4UWJ 7L5 7.30337
239 4UWJ MYA 7.30337
240 2ZQ0 ACR 7.30337
241 3T1A 5MA 7.30337
242 4D5B ACX 7.30337
243 5FP3 3JI 7.30337
244 3E85 BSU 7.59494
245 5FYR INS 7.86517
246 6CDO ALA VAL GLY ILE GLY ALA VAL PHE 7.86517
247 2R5V HHH 7.86517
248 1S5O 152 7.86517
249 2J3M PRI 7.86517
250 2J3M ATP 7.86517
251 6GBV FMN 8.21918
252 3RWP ABQ 8.42697
253 3QUZ QUV 8.42697
254 4OPC PGT 8.42697
255 3G08 FEE 8.42697
256 4OPC FDA 8.42697
257 3DLG GWE 8.42697
258 5J75 6GQ 8.42697
259 5FKP 6UL 8.42697
260 4LA7 A1O 8.42697
261 5AXH GLC GLC GLC GLC 8.42697
262 3RUG DB6 8.42697
263 5OCG 9R5 8.42697
264 4L9I 8PR 8.42697
265 6FA4 D1W 8.67052
266 1GT4 UNA 8.80503
267 5DEY 59T 8.98876
268 4IAW LIZ 8.98876
269 5AE2 FYC 8.98876
270 5DZT AMP 8.98876
271 6FE1 V14 8.98876
272 4YGF AZM 8.98876
273 4WOE ADP 8.98876
274 3GLC R5P 8.98876
275 1CLU DBG 9.03614
276 1OGX EQU 9.16031
277 3MTX PGT 9.27152
278 2YAK OSV 9.55056
279 2WSA 646 9.55056
280 2WSA MYA 9.55056
281 3PQB VGP 9.55056
282 2WKQ FMN 9.55056
283 3RI1 3RH 9.55056
284 4FHD 0TT 9.55056
285 4FHD EEM 9.55056
286 3HUJ AGH 10.1124
287 4WO4 JLS 10.1124
288 1YFS ALA 10.1124
289 5VNF VAL THR SER VAL VAL 10.1124
290 5FQK 6NT 10.1124
291 1MJJ HAL 10.1124
292 4K3H 1OM 10.1695
293 2E27 AB0 10.3175
294 1OUK 084 10.6742
295 4LOO SB4 10.6742
296 1VJY 460 10.6742
297 5UKL SIX 10.6742
298 1TFZ 869 10.6742
299 3PVW QRX 10.6742
300 2AG4 LP3 10.9756
301 2AG4 OLA 10.9756
302 3VQ2 LP4 LP5 MYR DAO 11.1111
303 4XIZ LPP 11.1765
304 4IGH 1EA 11.236
305 4IGH ORO 11.236
306 4IGH FMN 11.236
307 4BVM VCA 11.2782
308 2V0U FMN 11.6438
309 5DJU FMN 11.7241
310 5A5W GUO 11.7978
311 5X7Q ACR 11.7978
312 4GCZ FMN 11.7978
313 4QTB 38Z 11.7978
314 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 11.7978
315 2WBV SIA 11.7978
316 1M15 ADP 11.7978
317 1M15 ARG 11.7978
318 2GU8 796 12.3596
319 5N87 N66 12.3596
320 2CDO GAL AAL GAL AAL GAL AAL 12.3596
321 1YKD CMP 12.3596
322 2QIA U20 12.3596
323 1Z2I NAD 12.3596
324 2RDE C2E 12.3596
325 5C3R AKG 12.828
326 5C3R HMU 12.828
327 4K55 H6P 12.9032
328 1I82 BGC BGC 12.9213
329 6A1G 9OL 12.9213
330 5INJ 6C7 12.9213
331 4ZH7 FUC GAL NAG GAL FUC 12.9213
332 2I6A 5I5 12.9213
333 1UYY BGC BGC 12.9771
334 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 14.0449
335 2JDR L20 14.0449
336 1ODM ASV 14.6067
337 3G6K FAD 14.6067
338 4EES FMN 14.7826
339 2P7Q GG6 15.0376
340 5FUI APY 15.1515
341 1N5S ADL 15.1786
342 4WW7 AMP 15.7303
343 3KYG 5GP 5GP 15.7303
344 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 16.2921
345 1OGZ EQU 16.8
346 3MVH WFE 16.8539
347 2JLD AG1 17.9775
348 1UMZ BGC BGC XYS BGC XYS GAL 19.1011
349 2IO8 ADP 19.1011
350 5KEW 6SB 19.1489
351 4CS4 AXZ 19.6629
352 5KD6 LBU 20.2247
353 5KD6 6C7 20.2247
354 1MH5 HAL 20.2247
355 5H9P TD2 21.519
356 4H2X G5A 21.9101
357 4H2W AMP 21.9101
358 4H2W 5GP 21.9101
359 5EPQ OLA 21.9512
360 5NBW 8SK 23.0337
361 5NCF 8T5 30.9735
362 3VV1 GAL FUC 35.625
Pocket No.: 2; Query (leader) PDB : 3WG3; Ligand: A2G GAL NAG FUC; Similar sites found with APoc: 250
This union binding pocket(no: 2) in the query (biounit: 3wg3.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 5F3I 5UJ None
2 5N2F 8HW None
3 2QX0 PH2 None
4 1J3R 6PG None
5 2HRL SIA GAL SIA BGC NGA CEQ None
6 2FXD DR7 None
7 5KO1 6UY None
8 5TO8 7FM None
9 5NIU 8YZ None
10 1SU2 ATP None
11 5H2U 1N1 None
12 6D6L FY4 None
13 2YJ0 420 None
14 3S43 478 None
15 6ES0 BW8 1.1236
16 1QD1 FON 1.1236
17 3VNM SDD 1.1236
18 2Y6O 1N1 1.68539
19 4NJH SAM 1.68539
20 4NJH 2K8 1.68539
21 2Y3S TIR 1.68539
22 4P42 PEE 1.68539
23 5YU3 NAD 1.68539
24 5YU3 PRO 1.68539
25 4NST ADP 1.68539
26 3B1Q NOS 1.68539
27 4HIA FMN 1.70455
28 2AGC DAO 1.85185
29 6GG9 FMN 1.85185
30 5Y80 IRE 2.02703
31 4KBA 1QM 2.24719
32 4NAO AKG 2.24719
33 3VHE 42Q 2.24719
34 4J7Q B7N 2.24719
35 4HSJ 6PC 2.29885
36 4ZSI GLP 2.33918
37 3GZ8 APR 2.46914
38 4NFN 2KC 2.80899
39 3IU9 T07 2.80899
40 4RFM 3P6 2.80899
41 1TOI HCI 2.80899
42 4ZS4 ATP 2.80899
43 3BXO UPP 2.80899
44 1RP7 TZD 2.80899
45 4B1M FRU FRU 2.80899
46 5A3T MMK 2.80899
47 1Y2F WAI 2.8777
48 4B1L FRU 3.0303
49 3G5D 1N1 3.37079
50 4EWH T77 3.37079
51 3QP8 HL0 3.37079
52 2C49 ADN 3.37079
53 5I0U DCY 3.37079
54 5LIA 6XN 3.37079
55 5HMR FDZ 3.37079
56 5N5U 7N8 3.37079
57 5QIN J2V 3.37079
58 5XQW 8EU 3.37079
59 4UXL 5P8 3.37079
60 5MY8 RXZ 3.37079
61 5IVE 6E8 3.37079
62 1H4H XYP XYS XYP 3.37079
63 5XEG AKG 3.37079
64 3AKK ADP 3.37079
65 1I7E IBS 3.37079
66 2C49 ANP 3.37079
67 5ISY NAD 3.37079
68 1N9L FMN 3.66972
69 5AYT L6Y 3.77358
70 2Z6C FMN 3.87597
71 3FW9 SLX 3.93258
72 1DY4 SNP 3.93258
73 2OBD 2OB 3.93258
74 4WHZ 3NL 3.93258
75 1RJW ETF 3.93258
76 3EKK GS2 3.93258
77 1OJJ GLC GAL 3.93258
78 1OJK GLC BGC 3.93258
79 3RFA SAM 3.93258
80 4MLO PAM 3.93258
81 3RE4 TO1 3.93258
82 5H5A 6OU 3.93258
83 1ZP9 ATP 3.93258
84 4E93 GUI 3.93258
85 1VRP ADP 3.93258
86 4GQP B40 4.41767
87 1OPB RET 4.47761
88 5BVE 4VG 4.49438
89 2XVD AS6 4.49438
90 5EW9 5VC 4.49438
91 3ZXR P3S 4.49438
92 3ZXR IQ1 4.49438
93 2RG0 CTT 4.49438
94 4U03 TLL 4.49438
95 5KBF CMP 4.49438
96 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 4.49438
97 4J7H TLO 4.49438
98 1PVN MZP 4.49438
99 4XCB HY0 4.49438
100 4U98 ACP 4.49438
101 5DX9 T6P 4.49438
102 5VAD PRO 4.49438
103 2PR5 FMN 4.54545
104 4J6W CTP 4.87805
105 2ZMF CMP 5.05618
106 2HK5 1BM 5.05618
107 2OVW CBI 5.05618
108 1PN0 IPH 5.05618
109 2C78 PUL 5.05618
110 3FON VAL ASN ASP ILE PHE GLU ALA ILE 5.05618
111 4S3F 43W 5.05618
112 3FC2 IBI 5.05618
113 4PXL NAD 5.05618
114 1Z03 OCH 5.05618
115 2XCG XCG 5.05618
116 3LGS SAH 5.05618
117 3LGS ADE 5.05618
118 3PUR 2HG 5.05618
119 2IFW ACE PHE LYS PHE PSA LEU AAR 5.33981
120 6CZI 38E 5.35714
121 2GJ5 VD3 5.55556
122 3E8N VRA 5.61798
123 3E8N ATP 5.61798
124 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 5.61798
125 5JSP DQY 5.61798
126 3SLS ANP 5.61798
127 5EYP LOC 5.61798
128 5F2T PLM 5.61798
129 1HKK NAA NAA AMI 5.61798
130 5DS8 GLY 5CT GLY ALA 5.61798
131 4RLT FSE 5.6962
132 3JRS A8S 5.76923
133 3IS2 FAD 5.84416
134 3D72 FAD 6.04027
135 5GP0 GPP 6.04027
136 3SXS PP2 6.17978
137 3E7O 35F 6.17978
138 5H9Y BGC BGC BGC BGC 6.17978
139 4H6B 10X 6.17978
140 4H6B 10Y 6.17978
141 3QT6 2P0 6.17978
142 2Y88 2ER 6.17978
143 1ZZ7 S0H 6.17978
144 2Q0D ATP 6.17978
145 2GVJ DGB 6.17978
146 6G9I CXX 6.54762
147 5ML3 DL3 6.71141
148 5AE9 OKO 6.74157
149 4CQE CQE 6.74157
150 2ET1 GLV 6.74157
151 4WNK 453 6.74157
152 6EZ6 C5Z 6.74157
153 2GC0 PAN 6.74157
154 2TPI ILE VAL 6.89655
155 3A6T 8OG 6.97674
156 5TUF TDC 7.30337
157 1LOR BMP 7.30337
158 6FUL E7Z 7.30337
159 3WDX BGC BGC GLC 7.30337
160 4C2V YJA 7.30337
161 2GMH UQ5 7.30337
162 3A5Z KAA 7.30337
163 5Z46 8XL 7.86517
164 6CC0 EWM 7.86517
165 4BG4 ADP 7.86517
166 4KS7 X4Z 7.86517
167 2VRQ XYP XYP AHR 7.86517
168 1OLM VTQ 8.42697
169 4IGQ THR M3L GLN 8.42697
170 4MOB ADP 8.42697
171 3THR C2F 8.42697
172 1PZO CBT 8.42697
173 2Z6D FMN 8.46154
174 3BJK CIT 8.49673
175 5TFZ 7BC 8.66667
176 4X6F 3XU 8.98876
177 4P5Z Q7M 8.98876
178 5AE2 FAD 8.98876
179 3Q8G PEE 8.98876
180 5NBP BGC BGC BGC 8.98876
181 4RD0 GDP 8.98876
182 6CQF F97 8.98876
183 3C2O NTM 8.98876
184 3H0L ADP 8.98876
185 4IEN GDP 9.20245
186 2QL9 CIT 9.24856
187 4M1U A2G MBG 9.55056
188 2JEN GLC GLC BGC XYS BGC XYS 9.55056
189 1F52 ADP 9.55056
190 1KQW RTL 9.70149
191 4CVZ TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 10.1124
192 1DMY AZM 10.1124
193 3AMN CBK 10.1124
194 3AMN CBI 10.1124
195 6GR0 F8W 10.3448
196 2DIO EOD 10.6742
197 1HXD BTN 10.6742
198 3E9I XAH 10.6742
199 4ONA UW1 11.236
200 5T8O 76Z 11.236
201 3H5N ATP 11.236
202 5EZU MYR 11.236
203 3VMG 9CA 11.3043
204 5BU3 4W9 11.413
205 4RT1 C2E 11.6071
206 5EFW FMN 11.7241
207 5DJT FMN 11.7241
208 1REQ DCA 11.7978
209 5X7Q GLC GLC GLC GLC GLC 11.7978
210 5EH0 5NW 11.7978
211 5IXG OTP 11.8343
212 1EWJ BLM 11.9048
213 6GIN IR2 12.3596
214 5H2D ERG 12.3596
215 3HMO STU 12.3596
216 1RE8 BD2 12.3596
217 4NMC FAD 12.3596
218 4NMC 2OP 12.3596
219 3FW3 ETS 12.9213
220 2WQN ADP 12.9213
221 3MHA Z69 12.9213
222 3TKI S25 13.4831
223 3UH0 TSB 14.0449
224 1LFO OLA 14.0625
225 4NG2 OHN 14.1593
226 2QZT PLM 14.4144
227 5LUN OGA 14.6067
228 1U6R ADP 14.6067
229 3DAK ANP 14.6067
230 6GW1 CHO 15.1685
231 3B00 16A 15.1685
232 5K21 6QF 15.6028
233 1O97 AMP 15.7303
234 1NYW DAU 15.7303
235 1XIM XYL 16.2921
236 2QK4 ATP 16.8539
237 1Q11 TYE 16.8539
238 5K8S CMP 16.8919
239 5CJF 520 17.4157
240 1NJJ ORX 17.4157
241 4R3U 3HC 18.5393
242 4R3U 3KK 18.5393
243 5ZM4 AKG 18.5393
244 5DYO FLU 18.8679
245 5HES 032 19.1011
246 5FP4 YC8 19.1011
247 4OCX MT1 19.4444
248 4IE6 UN9 19.6629
249 4CS4 ANP 19.6629
250 3T4L ZEA 20.7865
APoc FAQ
Feedback